479434:STHE RS09965
gene id: 479434:STHE_RS09965
uniprot id: D1C589
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

479434:STHE RS06895
gene id: 479434:STHE_RS06895
uniprot id: D1C3I3
names: Similarity
messages: Belongs to the GARS family.

479434:STHE RS16315
gene id: 479434:STHE_RS16315
uniprot id: D1CA22
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

479434:STHE RS00055
gene id: 479434:STHE_RS00055
uniprot id: D1C5D4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

479434:STHE RS06510
gene id: 479434:STHE_RS06510
uniprot id: D1C3B1
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

479434:STHE RS09845
gene id: 479434:STHE_RS09845
uniprot id: D1C565
names: Similarity
messages: Belongs to the peptidase S9C family.

479434:STHE RS10165
gene id: 479434:STHE_RS10165
uniprot id: D1C5P5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

479434:STHE RS05240
gene id: 479434:STHE_RS05240
uniprot id: D1C2L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

479434:STHE RS00670
gene id: 479434:STHE_RS00670
uniprot id: D1C638
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

479434:STHE RS07195
gene id: 479434:STHE_RS07195
uniprot id: D1C3P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

479434:STHE RS17635
gene id: 479434:STHE_RS17635
uniprot id: D1C665
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

479434:STHE RS04630
gene id: 479434:STHE_RS04630
uniprot id: D1C293
names: Similarity
messages: Belongs to the peptidase C40 family.

479434:STHE RS02840
gene id: 479434:STHE_RS02840
uniprot id: D1C194
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

479434:STHE RS13595
gene id: 479434:STHE_RS13595
uniprot id: D1C8I5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

479434:STHE RS08560
gene id: 479434:STHE_RS08560
uniprot id: D1C4F8
names: Similarity
messages: Belongs to the UPF0235 family.

479434:STHE RS17115
gene id: 479434:STHE_RS17115
uniprot id: D1CAI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS09395
gene id: 479434:STHE_RS09395
uniprot id: D1C4X5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

479434:STHE RS06770
gene id: 479434:STHE_RS06770
uniprot id: D1C3G0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

479434:STHE RS16900
gene id: 479434:STHE_RS16900
uniprot id: D1CAE3
names: Similarity
messages: Belongs to the AOR/FOR family.

479434:STHE RS09380
gene id: 479434:STHE_RS09380
uniprot id: D1C4X2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

479434:STHE RS02190
gene id: 479434:STHE_RS02190
uniprot id: D1C7Q2
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

479434:STHE RS13970
gene id: 479434:STHE_RS13970
uniprot id: D1C8Q8
names: Similarity
messages: Belongs to the peptidase M24B family.

479434:STHE RS05015
gene id: 479434:STHE_RS05015
uniprot id: D1C2G8
names: Cofactor
names: Similarity
messages: Belongs to the cytochrome b560 family.
messages: The heme is bound between the two transmembrane subunits.

479434:STHE RS09640
gene id: 479434:STHE_RS09640
uniprot id: D1C524
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS09200
gene id: 479434:STHE_RS09200
uniprot id: D1C4T6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

479434:STHE RS06550
gene id: 479434:STHE_RS06550
uniprot id: D1C3B9
names: Subcellular Location Annotation
messages: Cytoplasm

479434:STHE RS06400
gene id: 479434:STHE_RS06400
uniprot id: D1C391
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

479434:STHE RS08395
gene id: 479434:STHE_RS08395
uniprot id: D1C4C4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

479434:STHE RS12150
gene id: 479434:STHE_RS12150
uniprot id: D1C7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

479434:STHE RS05755
gene id: 479434:STHE_RS05755
uniprot id: D1C2W6
names: Similarity
messages: Belongs to the FemABX family.

479434:STHE RS01690
gene id: 479434:STHE_RS01690
uniprot id: D1C723
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

479434:STHE RS15485
gene id: 479434:STHE_RS15485
uniprot id: D1C9K2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

479434:STHE RS00705
gene id: 479434:STHE_RS00705
uniprot id: D1C645
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

479434:STHE RS17550
gene id: 479434:STHE_RS17550
uniprot id: D1CAS1
names: Similarity
messages: Belongs to the TPP enzyme family.

479434:STHE RS04030
gene id: 479434:STHE_RS04030
uniprot id: D1C1X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

479434:STHE RS02805
gene id: 479434:STHE_RS02805
uniprot id: D1C186
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

479434:STHE RS11500
gene id: 479434:STHE_RS11500
uniprot id: D1C767
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

479434:STHE RS05820
gene id: 479434:STHE_RS05820
uniprot id: D1C2X7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS04395
gene id: 479434:STHE_RS04395
uniprot id: D1C249
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

479434:STHE RS10745
gene id: 479434:STHE_RS10745
uniprot id: D1C610
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS12195
gene id: 479434:STHE_RS12195
uniprot id: D1C7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

479434:STHE RS11645
gene id: 479434:STHE_RS11645
uniprot id: D1C796
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS14980
gene id: 479434:STHE_RS14980
uniprot id: D1C9A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS05360
gene id: 479434:STHE_RS05360
uniprot id: D1C2N9
names: Similarity
messages: Belongs to the peptidase S58 family.

479434:STHE RS09480
gene id: 479434:STHE_RS09480
uniprot id: D1C4Z2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS13205
gene id: 479434:STHE_RS13205
uniprot id: D1C8A6
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

479434:STHE RS09550
gene id: 479434:STHE_RS09550
uniprot id: D1C506
names: Cofactor
messages: Binds 1 FAD per subunit.

479434:STHE RS08535
gene id: 479434:STHE_RS08535
uniprot id: D1C4F3
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS01650
gene id: 479434:STHE_RS01650
uniprot id: D1C715
names: Function
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).

479434:STHE RS17565
gene id: 479434:STHE_RS17565
uniprot id: D1CAS4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

479434:STHE RS02580
gene id: 479434:STHE_RS02580
uniprot id: D1C141
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS12575
gene id: 479434:STHE_RS12575
uniprot id: D1CAY0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

479434:STHE RS07655
gene id: 479434:STHE_RS07655
uniprot id: D1C3Y6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS08520
gene id: 479434:STHE_RS08520
uniprot id: D1C4F0
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

479434:STHE RS05170
gene id: 479434:STHE_RS05170
uniprot id: D1C2K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

479434:STHE RS14535
gene id: 479434:STHE_RS14535
uniprot id: D1C920
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS00720
gene id: 479434:STHE_RS00720
uniprot id: D1C648
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

479434:STHE RS07375
gene id: 479434:STHE_RS07375
uniprot id: D1C3S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS07030
gene id: 479434:STHE_RS07030
uniprot id: D1C3K8
names: Subunit
messages: Homotetramer.

479434:STHE RS10570
gene id: 479434:STHE_RS10570
uniprot id: D1C5X4
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS01495
gene id: 479434:STHE_RS01495
uniprot id: D1C6Y4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS00455
gene id: 479434:STHE_RS00455
uniprot id: D1C5L6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

479434:STHE RS14385
gene id: 479434:STHE_RS14385
uniprot id: D1C8Z0
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS00815
gene id: 479434:STHE_RS00815
uniprot id: D1C667
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

479434:STHE RS06035
gene id: 479434:STHE_RS06035
uniprot id: D1C320
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

479434:STHE RS12725
gene id: 479434:STHE_RS12725
uniprot id: D1C814
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

479434:STHE RS06420
gene id: 479434:STHE_RS06420
uniprot id: D1C395
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS11840
gene id: 479434:STHE_RS11840
uniprot id: D1C7D5
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS12020
gene id: 479434:STHE_RS12020
uniprot id: D1C7G8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

479434:STHE RS08005
gene id: 479434:STHE_RS08005
uniprot id: D1C449
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

479434:STHE RS14795
gene id: 479434:STHE_RS14795
uniprot id: D1C965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS10245
gene id: 479434:STHE_RS10245
uniprot id: D1C5R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

479434:STHE RS05205
gene id: 479434:STHE_RS05205
uniprot id: D1C2K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

479434:STHE RS06040
gene id: 479434:STHE_RS06040
uniprot id: D1C321
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479434:STHE RS04695
gene id: 479434:STHE_RS04695
uniprot id: D1C2A5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

479434:STHE RS03075
gene id: 479434:STHE_RS03075
uniprot id: D1C1E0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

479434:STHE RS07285
gene id: 479434:STHE_RS07285
uniprot id: D1C3Q9
names: Similarity
messages: Belongs to the UPF0234 family.

479434:STHE RS03625
gene id: 479434:STHE_RS03625
uniprot id: D1C1Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

479434:STHE RS09120
gene id: 479434:STHE_RS09120
uniprot id: D1C4S0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

479434:STHE RS04795
gene id: 479434:STHE_RS04795
uniprot id: D1C2C5
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

479434:STHE RS01735
gene id: 479434:STHE_RS01735
uniprot id: D1C732
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

479434:STHE RS15175
gene id: 479434:STHE_RS15175
uniprot id: D1C9D9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

479434:STHE RS12255
gene id: 479434:STHE_RS12255
uniprot id: D1C7Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

479434:STHE RS13715
gene id: 479434:STHE_RS13715
uniprot id: D1C8K8
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07050
gene id: 479434:STHE_RS07050
uniprot id: D1C3L2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

479434:STHE RS01875
gene id: 479434:STHE_RS01875
uniprot id: D1C7I8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

479434:STHE RS13660
gene id: 479434:STHE_RS13660
uniprot id: D1C8J7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

479434:STHE RS12595
gene id: 479434:STHE_RS12595
uniprot id: D1CAY4
names: Similarity
messages: Belongs to the peptidase S9C family.

479434:STHE RS04890
gene id: 479434:STHE_RS04890
uniprot id: D1C2E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS01255
gene id: 479434:STHE_RS01255
uniprot id: D1C6T2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

479434:STHE RS10010
gene id: 479434:STHE_RS10010
uniprot id: D1C599
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

479434:STHE RS03840
gene id: 479434:STHE_RS03840
uniprot id: D1C1U0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

479434:STHE RS17580
gene id: 479434:STHE_RS17580
uniprot id: D1CAS7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

479434:STHE RS13260
gene id: 479434:STHE_RS13260
uniprot id: D1C8B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

479434:STHE RS16330
gene id: 479434:STHE_RS16330
uniprot id: D1CA25
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS09155
gene id: 479434:STHE_RS09155
uniprot id: D1C4S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS07675
gene id: 479434:STHE_RS07675
uniprot id: D1C3Z0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

479434:STHE RS06000
gene id: 479434:STHE_RS06000
uniprot id: D1C313
names: Similarity
messages: Belongs to the acylphosphatase family.

479434:STHE RS12270
gene id: 479434:STHE_RS12270
uniprot id: D1C7Z4
names: Similarity
messages: Belongs to the UPF0145 family.

479434:STHE RS12460
gene id: 479434:STHE_RS12460
uniprot id: D1CAV6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

479434:STHE RS17250
gene id: 479434:STHE_RS17250
uniprot id: D1CAL1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS04715
gene id: 479434:STHE_RS04715
uniprot id: D1C2A9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

479434:STHE RS05790
gene id: 479434:STHE_RS05790
uniprot id: D1C2X1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS15965
gene id: 479434:STHE_RS15965
uniprot id: D1C9V0
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS09755
gene id: 479434:STHE_RS09755
uniprot id: D1C547
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

479434:STHE RS06600
gene id: 479434:STHE_RS06600
uniprot id: D1C3C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

479434:STHE RS14340
gene id: 479434:STHE_RS14340
uniprot id: D1C8Y1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479434:STHE RS06005
gene id: 479434:STHE_RS06005
uniprot id: D1C314
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

479434:STHE RS06290
gene id: 479434:STHE_RS06290
uniprot id: D1C371
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

479434:STHE RS11000
gene id: 479434:STHE_RS11000
uniprot id: D1C6I6
names: Similarity
messages: Belongs to the peptidase S41A family.

479434:STHE RS16555
gene id: 479434:STHE_RS16555
uniprot id: D1CA70
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS08740
gene id: 479434:STHE_RS08740
uniprot id: D1C4J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

479434:STHE RS02850
gene id: 479434:STHE_RS02850
uniprot id: D1C196
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

479434:STHE RS15640
gene id: 479434:STHE_RS15640
uniprot id: D1C9N4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS09460
gene id: 479434:STHE_RS09460
uniprot id: D1C4Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

479434:STHE RS09180
gene id: 479434:STHE_RS09180
uniprot id: D1C4T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

479434:STHE RS13090
gene id: 479434:STHE_RS13090
uniprot id: D1C883
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: The exact nature of the substrate is currently not known. This entry has been annotated based on its similarity to Actinobacteria.

479434:STHE RS05750
gene id: 479434:STHE_RS05750
uniprot id: D1C2W5
names: Similarity
messages: Belongs to the FemABX family.

479434:STHE RS09470
gene id: 479434:STHE_RS09470
uniprot id: D1C4Z0
names: Similarity
messages: Belongs to the TrpF family.

479434:STHE RS09505
gene id: 479434:STHE_RS09505
uniprot id: D1C4Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS14025
gene id: 479434:STHE_RS14025
uniprot id: D1C8S0
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS13440
gene id: 479434:STHE_RS13440
uniprot id: D1C8F4
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS06130
gene id: 479434:STHE_RS06130
uniprot id: D1C339
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

479434:STHE RS11165
gene id: 479434:STHE_RS11165
uniprot id: D1C6L9
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS03800
gene id: 479434:STHE_RS03800
uniprot id: D1C1T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

479434:STHE RS12400
gene id: 479434:STHE_RS12400
uniprot id: D1CAU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

479434:STHE RS00675
gene id: 479434:STHE_RS00675
uniprot id: D1C639
names: Similarity
messages: Belongs to the peptidase S8 family.

479434:STHE RS03020
gene id: 479434:STHE_RS03020
uniprot id: D1C1C9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479434:STHE RS08135
gene id: 479434:STHE_RS08135
uniprot id: D1C474
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

479434:STHE RS16230
gene id: 479434:STHE_RS16230
uniprot id: D1CA03
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS00470
gene id: 479434:STHE_RS00470
uniprot id: D1C5L9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

479434:STHE RS05490
gene id: 479434:STHE_RS05490
uniprot id: D1C2R4
names: Similarity
messages: Belongs to the TPP enzyme family.

479434:STHE RS03810
gene id: 479434:STHE_RS03810
uniprot id: D1C1T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

479434:STHE RS06065
gene id: 479434:STHE_RS06065
uniprot id: D1C326
names: Similarity
messages: Belongs to the TlyA family.

479434:STHE RS17585
gene id: 479434:STHE_RS17585
uniprot id: D1CAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

479434:STHE RS02045
gene id: 479434:STHE_RS02045
uniprot id: D1C7M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

479434:STHE RS02690
gene id: 479434:STHE_RS02690
uniprot id: D1C163
names: Similarity
messages: Belongs to the FlgD family.

479434:STHE RS08630
gene id: 479434:STHE_RS08630
uniprot id: D1C4H1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07635
gene id: 479434:STHE_RS07635
uniprot id: D1C3Y2
names: Similarity
messages: Belongs to the UPF0173 family.

479434:STHE RS09735
gene id: 479434:STHE_RS09735
uniprot id: D1C543
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

479434:STHE RS05255
gene id: 479434:STHE_RS05255
uniprot id: D1C2L8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

479434:STHE RS03370
gene id: 479434:STHE_RS03370
uniprot id: D1C1J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS15570
gene id: 479434:STHE_RS15570
uniprot id: D1C9M0
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS16790
gene id: 479434:STHE_RS16790
uniprot id: D1CAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479434:STHE RS05145
gene id: 479434:STHE_RS05145
uniprot id: D1C2J6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS12130
gene id: 479434:STHE_RS12130
uniprot id: D1C7W4
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

479434:STHE RS00810
gene id: 479434:STHE_RS00810
uniprot id: D1C666
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

479434:STHE RS04955
gene id: 479434:STHE_RS04955
uniprot id: D1C2F6
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

479434:STHE RS10040
gene id: 479434:STHE_RS10040
uniprot id: D1C5A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

479434:STHE RS00445
gene id: 479434:STHE_RS00445
uniprot id: D1C5L4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

479434:STHE RS09500
gene id: 479434:STHE_RS09500
uniprot id: D1C4Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS09525
gene id: 479434:STHE_RS09525
uniprot id: D1C501
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

479434:STHE RS10965
gene id: 479434:STHE_RS10965
uniprot id: D1C6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479434:STHE RS00550
gene id: 479434:STHE_RS00550
uniprot id: D1C5N5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

479434:STHE RS02340
gene id: 479434:STHE_RS02340
uniprot id: D1C7T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.

479434:STHE RS17490
gene id: 479434:STHE_RS17490
uniprot id: D1CAQ9
names: Similarity
messages: Belongs to the DapA family.

479434:STHE RS07260
gene id: 479434:STHE_RS07260
uniprot id: D1C3Q5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS07555
gene id: 479434:STHE_RS07555
uniprot id: D1C3W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS07840
gene id: 479434:STHE_RS07840
uniprot id: D1C423
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS00310
gene id: 479434:STHE_RS00310
uniprot id: D1C5I6
names: Similarity
messages: Belongs to the universal stress protein A family.

479434:STHE RS11430
gene id: 479434:STHE_RS11430
uniprot id: D1C752
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

479434:STHE RS17110
gene id: 479434:STHE_RS17110
uniprot id: D1CAI3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

479434:STHE RS12215
gene id: 479434:STHE_RS12215
uniprot id: D1C7Y2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

479434:STHE RS15825
gene id: 479434:STHE_RS15825
uniprot id: D1C9S1
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479434:STHE RS11855
gene id: 479434:STHE_RS11855
uniprot id: D1C7D7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

479434:STHE RS17730
gene id: 479434:STHE_RS17730
uniprot id: D1C185
names: Similarity
messages: Belongs to the FlgM family.

479434:STHE RS16430
gene id: 479434:STHE_RS16430
uniprot id: D1CA46
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS11670
gene id: 479434:STHE_RS11670
uniprot id: D1C7A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

479434:STHE RS14680
gene id: 479434:STHE_RS14680
uniprot id: D1C943
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

479434:STHE RS14525
gene id: 479434:STHE_RS14525
uniprot id: D1C918
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

479434:STHE RS05210
gene id: 479434:STHE_RS05210
uniprot id: D1C2K9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

479434:STHE RS12920
gene id: 479434:STHE_RS12920
uniprot id: D1C850
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

479434:STHE RS16820
gene id: 479434:STHE_RS16820
uniprot id: D1CAC7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

479434:STHE RS14790
gene id: 479434:STHE_RS14790
uniprot id: D1C964
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS05175
gene id: 479434:STHE_RS05175
uniprot id: D1C2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

479434:STHE RS05560
gene id: 479434:STHE_RS05560
uniprot id: D1C2S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

479434:STHE RS04845
gene id: 479434:STHE_RS04845
uniprot id: D1C2D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

479434:STHE RS12735
gene id: 479434:STHE_RS12735
uniprot id: D1C816
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07575
gene id: 479434:STHE_RS07575
uniprot id: D1C3X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

479434:STHE RS06740
gene id: 479434:STHE_RS06740
uniprot id: D1C3F3
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS13125
gene id: 479434:STHE_RS13125
uniprot id: D1C890
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

479434:STHE RS04700
gene id: 479434:STHE_RS04700
uniprot id: D1C2A6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS13255
gene id: 479434:STHE_RS13255
uniprot id: D1C8B7
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

479434:STHE RS06655
gene id: 479434:STHE_RS06655
uniprot id: D1C3D9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

479434:STHE RS11760
gene id: 479434:STHE_RS11760
uniprot id: D1C7B9
names: Similarity
messages: Belongs to the threonine aldolase family.

479434:STHE RS06660
gene id: 479434:STHE_RS06660
uniprot id: D1C3E0
names: Similarity
messages: Belongs to the UPF0434 family.

479434:STHE RS06475
gene id: 479434:STHE_RS06475
uniprot id: D1C3A4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

479434:STHE RS11535
gene id: 479434:STHE_RS11535
uniprot id: D1C774
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

479434:STHE RS11540
gene id: 479434:STHE_RS11540
uniprot id: D1C775
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS05180
gene id: 479434:STHE_RS05180
uniprot id: D1C2K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

479434:STHE RS02785
gene id: 479434:STHE_RS02785
uniprot id: D1C182
names: Similarity
messages: Belongs to the bacterial flagellin family.

479434:STHE RS07540
gene id: 479434:STHE_RS07540
uniprot id: D1C3W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

479434:STHE RS09130
gene id: 479434:STHE_RS09130
uniprot id: D1C4S2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

479434:STHE RS01425
gene id: 479434:STHE_RS01425
uniprot id: D1C6X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479434:STHE RS14750
gene id: 479434:STHE_RS14750
uniprot id: D1C955
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

479434:STHE RS11870
gene id: 479434:STHE_RS11870
uniprot id: D1C7E0
names: Similarity
messages: Belongs to the manganese catalase family.

479434:STHE RS02575
gene id: 479434:STHE_RS02575
uniprot id: D1C140
names: Similarity
messages: Belongs to the GSP E family.

479434:STHE RS12585
gene id: 479434:STHE_RS12585
uniprot id: D1CAY2
names: Similarity
messages: Belongs to the peptidase S11 family.

479434:STHE RS09600
gene id: 479434:STHE_RS09600
uniprot id: D1C516
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

479434:STHE RS15555
gene id: 479434:STHE_RS15555
uniprot id: D1C9L6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

479434:STHE RS03315
gene id: 479434:STHE_RS03315
uniprot id: D1C1I9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

479434:STHE RS03855
gene id: 479434:STHE_RS03855
uniprot id: D1C1U2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479434:STHE RS16335
gene id: 479434:STHE_RS16335
uniprot id: D1CA26
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS13455
gene id: 479434:STHE_RS13455
uniprot id: D1C8F7
names: Similarity
messages: Belongs to the threonine synthase family.

479434:STHE RS03595
gene id: 479434:STHE_RS03595
uniprot id: D1C1P4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

479434:STHE RS11880
gene id: 479434:STHE_RS11880
uniprot id: D1C7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

479434:STHE RS11400
gene id: 479434:STHE_RS11400
uniprot id: D1C6R7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07235
gene id: 479434:STHE_RS07235
uniprot id: D1C3P9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

479434:STHE RS13790
gene id: 479434:STHE_RS13790
uniprot id: D1C8M3
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS02295
gene id: 479434:STHE_RS02295
uniprot id: D1C7S2
names: Similarity
messages: Belongs to the ParB family.

479434:STHE RS14440
gene id: 479434:STHE_RS14440
uniprot id: D1C901
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS03950
gene id: 479434:STHE_RS03950
uniprot id: D1C1W0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

479434:STHE RS14690
gene id: 479434:STHE_RS14690
uniprot id: D1C945
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS02740
gene id: 479434:STHE_RS02740
uniprot id: D1C173
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

479434:STHE RS15765
gene id: 479434:STHE_RS15765
uniprot id: D1C9R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479434:STHE RS04455
gene id: 479434:STHE_RS04455
uniprot id: D1C259
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

479434:STHE RS16955
gene id: 479434:STHE_RS16955
uniprot id: D1CAF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS13895
gene id: 479434:STHE_RS13895
uniprot id: D1C8P3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

479434:STHE RS04180
gene id: 479434:STHE_RS04180
uniprot id: D1C207
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

479434:STHE RS09145
gene id: 479434:STHE_RS09145
uniprot id: D1C4S5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

479434:STHE RS06250
gene id: 479434:STHE_RS06250
uniprot id: D1C363
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

479434:STHE RS01470
gene id: 479434:STHE_RS01470
uniprot id: D1C6X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479434:STHE RS08745
gene id: 479434:STHE_RS08745
uniprot id: D1C4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

479434:STHE RS15815
gene id: 479434:STHE_RS15815
uniprot id: D1C9R9
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

479434:STHE RS15110
gene id: 479434:STHE_RS15110
uniprot id: D1C9C7
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

479434:STHE RS08050
gene id: 479434:STHE_RS08050
uniprot id: D1C458
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

479434:STHE RS01915
gene id: 479434:STHE_RS01915
uniprot id: D1C7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

479434:STHE RS13285
gene id: 479434:STHE_RS13285
uniprot id: D1C8C3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

479434:STHE RS02870
gene id: 479434:STHE_RS02870
uniprot id: D1C1A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

479434:STHE RS11090
gene id: 479434:STHE_RS11090
uniprot id: D1C6K4
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS11865
gene id: 479434:STHE_RS11865
uniprot id: D1C7D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

479434:STHE RS11860
gene id: 479434:STHE_RS11860
uniprot id: D1C7D8
names: Similarity
messages: Belongs to the group II decarboxylase family.

479434:STHE RS01430
gene id: 479434:STHE_RS01430
uniprot id: D1C6X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479434:STHE RS11440
gene id: 479434:STHE_RS11440
uniprot id: D1C754
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS03455
gene id: 479434:STHE_RS03455
uniprot id: D1C1L6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS01410
gene id: 479434:STHE_RS01410
uniprot id: D1C6W7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS10265
gene id: 479434:STHE_RS10265
uniprot id: D1C5R6
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

479434:STHE RS14985
gene id: 479434:STHE_RS14985
uniprot id: D1C9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS14595
gene id: 479434:STHE_RS14595
uniprot id: D1C930
names: Similarity
messages: Belongs to the peptidase M29 family.

479434:STHE RS07835
gene id: 479434:STHE_RS07835
uniprot id: D1C422
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

479434:STHE RS02610
gene id: 479434:STHE_RS02610
uniprot id: D1C147
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS05280
gene id: 479434:STHE_RS05280
uniprot id: D1C2M3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

479434:STHE RS00185
gene id: 479434:STHE_RS00185
uniprot id: D1C5G1
names: Similarity
messages: Belongs to the SCO1/2 family.

479434:STHE RS06330
gene id: 479434:STHE_RS06330
uniprot id: D1C379
names: Similarity
messages: Belongs to the ribF family.

479434:STHE RS12505
gene id: 479434:STHE_RS12505
uniprot id: D1CAW6
names: Similarity
messages: Belongs to the HupF/HypC family.

479434:STHE RS09880
gene id: 479434:STHE_RS09880
uniprot id: D1C572
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

479434:STHE RS16325
gene id: 479434:STHE_RS16325
uniprot id: D1CA24
names: Similarity
messages: Belongs to the peptidase A24 family.

479434:STHE RS11140
gene id: 479434:STHE_RS11140
uniprot id: D1C6L4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS02405
gene id: 479434:STHE_RS02405
uniprot id: D1C7U4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

479434:STHE RS03395
gene id: 479434:STHE_RS03395
uniprot id: D1C1K4
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

479434:STHE RS12280
gene id: 479434:STHE_RS12280
uniprot id: D1C7Z6
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS01675
gene id: 479434:STHE_RS01675
uniprot id: D1C720
names: Cofactor
messages: Binds 1 FAD per subunit.

479434:STHE RS04175
gene id: 479434:STHE_RS04175
uniprot id: D1C206
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

479434:STHE RS16285
gene id: 479434:STHE_RS16285
uniprot id: D1CA16
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

479434:STHE RS06855
gene id: 479434:STHE_RS06855
uniprot id: D1C3H5
names: Similarity
messages: Belongs to the peptidase S9C family.

479434:STHE RS03010
gene id: 479434:STHE_RS03010
uniprot id: D1C1C7
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

479434:STHE RS01895
gene id: 479434:STHE_RS01895
uniprot id: D1C7J2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS04515
gene id: 479434:STHE_RS04515
uniprot id: D1C270
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

479434:STHE RS10805
gene id: 479434:STHE_RS10805
uniprot id: D1C6E9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

479434:STHE RS01250
gene id: 479434:STHE_RS01250
uniprot id: D1C6T1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

479434:STHE RS05005
gene id: 479434:STHE_RS05005
uniprot id: D1C2G6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

479434:STHE RS05100
gene id: 479434:STHE_RS05100
uniprot id: D1C2I6
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

479434:STHE RS07640
gene id: 479434:STHE_RS07640
uniprot id: D1C3Y3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

479434:STHE RS00800
gene id: 479434:STHE_RS00800
uniprot id: D1C664
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

479434:STHE RS07600
gene id: 479434:STHE_RS07600
uniprot id: D1C3X5
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS01750
gene id: 479434:STHE_RS01750
uniprot id: D1C735
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

479434:STHE RS08215
gene id: 479434:STHE_RS08215
uniprot id: D1C488
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

479434:STHE RS01290
gene id: 479434:STHE_RS01290
uniprot id: D1C6T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS03920
gene id: 479434:STHE_RS03920
uniprot id: D1C1V4
names: Similarity
messages: Belongs to the threonine synthase family.

479434:STHE RS01960
gene id: 479434:STHE_RS01960
uniprot id: D1C7K5
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS05230
gene id: 479434:STHE_RS05230
uniprot id: D1C2L3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

479434:STHE RS14370
gene id: 479434:STHE_RS14370
uniprot id: D1C8Y7
names: Similarity
messages: Belongs to the glutamine synthetase family.

479434:STHE RS09070
gene id: 479434:STHE_RS09070
uniprot id: D1C4R0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479434:STHE RS04915
gene id: 479434:STHE_RS04915
uniprot id: D1C2E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

479434:STHE RS01450
gene id: 479434:STHE_RS01450
uniprot id: D1C6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479434:STHE RS10205
gene id: 479434:STHE_RS10205
uniprot id: D1C5Q4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

479434:STHE RS12790
gene id: 479434:STHE_RS12790
uniprot id: D1C827
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS08270
gene id: 479434:STHE_RS08270
uniprot id: D1C498
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS16640
gene id: 479434:STHE_RS16640
uniprot id: D1CA88
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

479434:STHE RS00065
gene id: 479434:STHE_RS00065
uniprot id: D1C5D6
names: Similarity
messages: Belongs to the UPF0111 family.

479434:STHE RS00035
gene id: 479434:STHE_RS00035
uniprot id: D1C5D0
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

479434:STHE RS06995
gene id: 479434:STHE_RS06995
uniprot id: D1C3K1
names: Similarity
messages: Belongs to the RecJ family.

479434:STHE RS09730
gene id: 479434:STHE_RS09730
uniprot id: D1C542
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

479434:STHE RS14020
gene id: 479434:STHE_RS14020
uniprot id: D1C8R9
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS04785
gene id: 479434:STHE_RS04785
uniprot id: D1C2C3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

479434:STHE RS08815
gene id: 479434:STHE_RS08815
uniprot id: D1C4K7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS08160
gene id: 479434:STHE_RS08160
uniprot id: D1C478
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

479434:STHE RS16860
gene id: 479434:STHE_RS16860
uniprot id: D1CAD5
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07435
gene id: 479434:STHE_RS07435
uniprot id: D1C3U0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

479434:STHE RS13050
gene id: 479434:STHE_RS13050
uniprot id: D1C875
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS10600
gene id: 479434:STHE_RS10600
uniprot id: D1C5Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

479434:STHE RS07370
gene id: 479434:STHE_RS07370
uniprot id: D1C3S7
names: Similarity
messages: Belongs to the threonine synthase family.

479434:STHE RS15950
gene id: 479434:STHE_RS15950
uniprot id: D1C9U6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

479434:STHE RS08440
gene id: 479434:STHE_RS08440
uniprot id: D1C4D3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

479434:STHE RS16215
gene id: 479434:STHE_RS16215
uniprot id: D1CA00
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

479434:STHE RS05250
gene id: 479434:STHE_RS05250
uniprot id: D1C2L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

479434:STHE RS15780
gene id: 479434:STHE_RS15780
uniprot id: D1C9R3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

479434:STHE RS06780
gene id: 479434:STHE_RS06780
uniprot id: D1C3G2
names: Similarity
messages: Belongs to the HypE family.

479434:STHE RS06805
gene id: 479434:STHE_RS06805
uniprot id: D1C3G7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

479434:STHE RS04090
gene id: 479434:STHE_RS04090
uniprot id: D1C1Y8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

479434:STHE RS01265
gene id: 479434:STHE_RS01265
uniprot id: D1C6T4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

479434:STHE RS09570
gene id: 479434:STHE_RS09570
uniprot id: D1C510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS12005
gene id: 479434:STHE_RS12005
uniprot id: D1C7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

479434:STHE RS11895
gene id: 479434:STHE_RS11895
uniprot id: D1C7E5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

479434:STHE RS07110
gene id: 479434:STHE_RS07110
uniprot id: D1C3M4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

479434:STHE RS07215
gene id: 479434:STHE_RS07215
uniprot id: D1C3P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

479434:STHE RS17695
gene id: 479434:STHE_RS17695
uniprot id: D1C7P5
names: Similarity
messages: Belongs to the peptidase S11 family.

479434:STHE RS05990
gene id: 479434:STHE_RS05990
uniprot id: D1C311
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

479434:STHE RS15885
gene id: 479434:STHE_RS15885
uniprot id: D1C9T3
names: Similarity
messages: Belongs to the NodU/CmcH family.

479434:STHE RS10430
gene id: 479434:STHE_RS10430
uniprot id: D1C5V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

479434:STHE RS03360
gene id: 479434:STHE_RS03360
uniprot id: D1C1J7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS04590
gene id: 479434:STHE_RS04590
uniprot id: D1C285
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

479434:STHE RS12785
gene id: 479434:STHE_RS12785
uniprot id: D1C826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS06370
gene id: 479434:STHE_RS06370
uniprot id: D1C385
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

479434:STHE RS06565
gene id: 479434:STHE_RS06565
uniprot id: D1C3C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

479434:STHE RS12015
gene id: 479434:STHE_RS12015
uniprot id: D1C7G7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS06275
gene id: 479434:STHE_RS06275
uniprot id: D1C368
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

479434:STHE RS04575
gene id: 479434:STHE_RS04575
uniprot id: D1C282
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

479434:STHE RS08785
gene id: 479434:STHE_RS08785
uniprot id: D1C4K1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

479434:STHE RS12950
gene id: 479434:STHE_RS12950
uniprot id: D1C855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

479434:STHE RS05195
gene id: 479434:STHE_RS05195
uniprot id: D1C2K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

479434:STHE RS16985
gene id: 479434:STHE_RS16985
uniprot id: D1CAF9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

479434:STHE RS11960
gene id: 479434:STHE_RS11960
uniprot id: D1C7F6
names: Similarity
messages: Belongs to the AHA1 family.

479434:STHE RS05040
gene id: 479434:STHE_RS05040
uniprot id: D1C2H3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

479434:STHE RS03485
gene id: 479434:STHE_RS03485
uniprot id: D1C1M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

479434:STHE RS01760
gene id: 479434:STHE_RS01760
uniprot id: D1C737
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479434:STHE RS13810
gene id: 479434:STHE_RS13810
uniprot id: D1C8M7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

479434:STHE RS02845
gene id: 479434:STHE_RS02845
uniprot id: D1C195
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

479434:STHE RS01505
gene id: 479434:STHE_RS01505
uniprot id: D1C6Y6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS15630
gene id: 479434:STHE_RS15630
uniprot id: D1C9N2
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS15835
gene id: 479434:STHE_RS15835
uniprot id: D1C9S3
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

479434:STHE RS03600
gene id: 479434:STHE_RS03600
uniprot id: D1C1P5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

479434:STHE RS11495
gene id: 479434:STHE_RS11495
uniprot id: D1C766
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

479434:STHE RS09695
gene id: 479434:STHE_RS09695
uniprot id: D1C535
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

479434:STHE RS06470
gene id: 479434:STHE_RS06470
uniprot id: D1C3A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

479434:STHE RS13850
gene id: 479434:STHE_RS13850
uniprot id: D1C8N5
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS13025
gene id: 479434:STHE_RS13025
uniprot id: D1C870
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS08900
gene id: 479434:STHE_RS08900
uniprot id: D1C4M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

479434:STHE RS15145
gene id: 479434:STHE_RS15145
uniprot id: D1C9D3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

479434:STHE RS13210
gene id: 479434:STHE_RS13210
uniprot id: D1C8A7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

479434:STHE RS01075
gene id: 479434:STHE_RS01075
uniprot id: D1C6B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS00205
gene id: 479434:STHE_RS00205
uniprot id: D1C5G5
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

479434:STHE RS13405
gene id: 479434:STHE_RS13405
uniprot id: D1C8E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS07810
gene id: 479434:STHE_RS07810
uniprot id: D1C417
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

479434:STHE RS15785
gene id: 479434:STHE_RS15785
uniprot id: D1C9R4
names: Similarity
messages: Belongs to the creatininase superfamily.

479434:STHE RS06425
gene id: 479434:STHE_RS06425
uniprot id: D1C396
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS11060
gene id: 479434:STHE_RS11060
uniprot id: D1C6J8
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07870
gene id: 479434:STHE_RS07870
uniprot id: D1C426
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

479434:STHE RS11190
gene id: 479434:STHE_RS11190
uniprot id: D1C6M2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS05835
gene id: 479434:STHE_RS05835
uniprot id: D1C2Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

479434:STHE RS08010
gene id: 479434:STHE_RS08010
uniprot id: D1C450
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

479434:STHE RS13015
gene id: 479434:STHE_RS13015
uniprot id: D1C868
names: Similarity
messages: Belongs to the CapA family.

479434:STHE RS09490
gene id: 479434:STHE_RS09490
uniprot id: D1C4Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

479434:STHE RS05600
gene id: 479434:STHE_RS05600
uniprot id: D1C2T5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

479434:STHE RS09045
gene id: 479434:STHE_RS09045
uniprot id: D1C4Q5
names: Similarity
messages: Belongs to the PrpD family.

479434:STHE RS09825
gene id: 479434:STHE_RS09825
uniprot id: D1C561
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

479434:STHE RS02185
gene id: 479434:STHE_RS02185
uniprot id: D1C7Q1
names: Similarity
messages: Belongs to the peptidase M20A family.

479434:STHE RS18150
gene id: 479434:STHE_RS18150
uniprot id: D1C8D1
names: Similarity
messages: Belongs to the ParB family.

479434:STHE RS07200
gene id: 479434:STHE_RS07200
uniprot id: D1C3P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

479434:STHE RS06530
gene id: 479434:STHE_RS06530
uniprot id: D1C3B5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

479434:STHE RS07190
gene id: 479434:STHE_RS07190
uniprot id: D1C3P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

479434:STHE RS16830
gene id: 479434:STHE_RS16830
uniprot id: D1CAC9
names: Similarity
messages: Belongs to the PrpD family.

479434:STHE RS00870
gene id: 479434:STHE_RS00870
uniprot id: D1C678
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS02520
gene id: 479434:STHE_RS02520
uniprot id: D1C135
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

479434:STHE RS11040
gene id: 479434:STHE_RS11040
uniprot id: D1C6J4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

479434:STHE RS06365
gene id: 479434:STHE_RS06365
uniprot id: D1C384
names: Similarity
messages: Belongs to the peptidase S33 family.

479434:STHE RS11005
gene id: 479434:STHE_RS11005
uniprot id: D1C6I7
names: Similarity
messages: Belongs to the peptidase S1C family.

479434:STHE RS00195
gene id: 479434:STHE_RS00195
uniprot id: D1C5G3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

479434:STHE RS03805
gene id: 479434:STHE_RS03805
uniprot id: D1C1T4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

479434:STHE RS10500
gene id: 479434:STHE_RS10500
uniprot id: D1C5W0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479434:STHE RS13340
gene id: 479434:STHE_RS13340
uniprot id: D1C8D4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS16550
gene id: 479434:STHE_RS16550
uniprot id: D1CA69
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

479434:STHE RS16610
gene id: 479434:STHE_RS16610
uniprot id: D1CA82
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS06060
gene id: 479434:STHE_RS06060
uniprot id: D1C325
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

479434:STHE RS05270
gene id: 479434:STHE_RS05270
uniprot id: D1C2M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

479434:STHE RS08185
gene id: 479434:STHE_RS08185
uniprot id: D1C481
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

479434:STHE RS08890
gene id: 479434:STHE_RS08890
uniprot id: D1C4M3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

479434:STHE RS15180
gene id: 479434:STHE_RS15180
uniprot id: D1C9E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

479434:STHE RS03955
gene id: 479434:STHE_RS03955
uniprot id: D1C1W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

479434:STHE RS09300
gene id: 479434:STHE_RS09300
uniprot id: D1C4V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

479434:STHE RS14420
gene id: 479434:STHE_RS14420
uniprot id: D1C8Z7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

479434:STHE RS03980
gene id: 479434:STHE_RS03980
uniprot id: D1C1W6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

479434:STHE RS10125
gene id: 479434:STHE_RS10125
uniprot id: D1C5C2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

479434:STHE RS12895
gene id: 479434:STHE_RS12895
uniprot id: D1C848
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

479434:STHE RS07750
gene id: 479434:STHE_RS07750
uniprot id: D1C405
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS14270
gene id: 479434:STHE_RS14270
uniprot id: D1C8W7
names: Similarity
messages: Belongs to the creatininase superfamily.

479434:STHE RS00425
gene id: 479434:STHE_RS00425
uniprot id: D1C5L0
names: Similarity
messages: Belongs to the DapA family.

479434:STHE RS05000
gene id: 479434:STHE_RS05000
uniprot id: D1C2G5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

479434:STHE RS03135
gene id: 479434:STHE_RS03135
uniprot id: D1C1F2
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

479434:STHE RS08485
gene id: 479434:STHE_RS08485
uniprot id: D1C4E3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

479434:STHE RS10415
gene id: 479434:STHE_RS10415
uniprot id: D1C5U7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS16485
gene id: 479434:STHE_RS16485
uniprot id: D1CA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS05960
gene id: 479434:STHE_RS05960
uniprot id: D1C305
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS11185
gene id: 479434:STHE_RS11185
uniprot id: D1C6M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

479434:STHE RS05810
gene id: 479434:STHE_RS05810
uniprot id: D1C2X5
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS09020
gene id: 479434:STHE_RS09020
uniprot id: D1C4Q0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

479434:STHE RS18110
gene id: 479434:STHE_RS18110
uniprot id: D1C7Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane

479434:STHE RS03680
gene id: 479434:STHE_RS03680
uniprot id: D1C1R0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

479434:STHE RS04625
gene id: 479434:STHE_RS04625
uniprot id: D1C292
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

479434:STHE RS05245
gene id: 479434:STHE_RS05245
uniprot id: D1C2L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

479434:STHE RS07150
gene id: 479434:STHE_RS07150
uniprot id: D1C3N2
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

479434:STHE RS04245
gene id: 479434:STHE_RS04245
uniprot id: D1C220
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS04655
gene id: 479434:STHE_RS04655
uniprot id: D1C297
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS06120
gene id: 479434:STHE_RS06120
uniprot id: D1C337
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

479434:STHE RS01800
gene id: 479434:STHE_RS01800
uniprot id: D1C745
names: Similarity
messages: Belongs to the PstS family.

479434:STHE RS04970
gene id: 479434:STHE_RS04970
uniprot id: D1C2F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

479434:STHE RS03670
gene id: 479434:STHE_RS03670
uniprot id: D1C1Q8
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS05570
gene id: 479434:STHE_RS05570
uniprot id: D1C2T0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

479434:STHE RS03230
gene id: 479434:STHE_RS03230
uniprot id: D1C1H3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

479434:STHE RS10675
gene id: 479434:STHE_RS10675
uniprot id: D1C5Z6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

479434:STHE RS02630
gene id: 479434:STHE_RS02630
uniprot id: D1C151
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479434:STHE RS06030
gene id: 479434:STHE_RS06030
uniprot id: D1C319
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479434:STHE RS15275
gene id: 479434:STHE_RS15275
uniprot id: D1C9G1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS06795
gene id: 479434:STHE_RS06795
uniprot id: D1C3G5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

479434:STHE RS08175
gene id: 479434:STHE_RS08175
uniprot id: D1C479
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

479434:STHE RS05215
gene id: 479434:STHE_RS05215
uniprot id: D1C2L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

479434:STHE RS15000
gene id: 479434:STHE_RS15000
uniprot id: D1C9A5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

479434:STHE RS00610
gene id: 479434:STHE_RS00610
uniprot id: D1C625
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07940
gene id: 479434:STHE_RS07940
uniprot id: D1C439
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

479434:STHE RS07910
gene id: 479434:STHE_RS07910
uniprot id: D1C434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

479434:STHE RS11485
gene id: 479434:STHE_RS11485
uniprot id: D1C764
names: Similarity
messages: Belongs to the universal stress protein A family.

479434:STHE RS05265
gene id: 479434:STHE_RS05265
uniprot id: D1C2M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

479434:STHE RS08325
gene id: 479434:STHE_RS08325
uniprot id: D1C4A9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

479434:STHE RS01825
gene id: 479434:STHE_RS01825
uniprot id: D1C7H8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

479434:STHE RS07155
gene id: 479434:STHE_RS07155
uniprot id: D1C3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

479434:STHE RS04760
gene id: 479434:STHE_RS04760
uniprot id: D1C2B8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

479434:STHE RS13020
gene id: 479434:STHE_RS13020
uniprot id: D1C869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS04705
gene id: 479434:STHE_RS04705
uniprot id: D1C2A7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS08075
gene id: 479434:STHE_RS08075
uniprot id: D1C463
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

479434:STHE RS04215
gene id: 479434:STHE_RS04215
uniprot id: D1C214
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

479434:STHE RS13240
gene id: 479434:STHE_RS13240
uniprot id: D1C8B4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS12310
gene id: 479434:STHE_RS12310
uniprot id: D1C802
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

479434:STHE RS03615
gene id: 479434:STHE_RS03615
uniprot id: D1C1P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

479434:STHE RS12205
gene id: 479434:STHE_RS12205
uniprot id: D1C7Y0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS06295
gene id: 479434:STHE_RS06295
uniprot id: D1C372
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

479434:STHE RS14315
gene id: 479434:STHE_RS14315
uniprot id: D1C8X6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

479434:STHE RS02635
gene id: 479434:STHE_RS02635
uniprot id: D1C152
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479434:STHE RS12225
gene id: 479434:STHE_RS12225
uniprot id: D1C7Y4
names: Similarity
messages: Belongs to the peptidase S9A family.

479434:STHE RS05275
gene id: 479434:STHE_RS05275
uniprot id: D1C2M2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

479434:STHE RS17725
gene id: 479434:STHE_RS17725
uniprot id: D1C155
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

479434:STHE RS09760
gene id: 479434:STHE_RS09760
uniprot id: D1C548
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

479434:STHE RS08430
gene id: 479434:STHE_RS08430
uniprot id: D1C4D1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

479434:STHE RS02885
gene id: 479434:STHE_RS02885
uniprot id: D1C1A3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

479434:STHE RS05625
gene id: 479434:STHE_RS05625
uniprot id: D1C2U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

479434:STHE RS06410
gene id: 479434:STHE_RS06410
uniprot id: D1C393
names: Similarity
messages: Belongs to the peptidase S58 family.

479434:STHE RS09625
gene id: 479434:STHE_RS09625
uniprot id: D1C521
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

479434:STHE RS11345
gene id: 479434:STHE_RS11345
uniprot id: D1C6Q4
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

479434:STHE RS01190
gene id: 479434:STHE_RS01190
uniprot id: D1C6E2
names: Similarity
messages: Belongs to the SCO1/2 family.

479434:STHE RS09820
gene id: 479434:STHE_RS09820
uniprot id: D1C560
names: Similarity
messages: Belongs to the AlaDH/PNT family.

479434:STHE RS12565
gene id: 479434:STHE_RS12565
uniprot id: D1CAX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS08400
gene id: 479434:STHE_RS08400
uniprot id: D1C4C5
names: Similarity
messages: Belongs to the ArsC family.

479434:STHE RS10335
gene id: 479434:STHE_RS10335
uniprot id: D1C5T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

479434:STHE RS07690
gene id: 479434:STHE_RS07690
uniprot id: D1C3Z3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

479434:STHE RS17210
gene id: 479434:STHE_RS17210
uniprot id: D1CAK4
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS02005
gene id: 479434:STHE_RS02005
uniprot id: D1C7L4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

479434:STHE RS01745
gene id: 479434:STHE_RS01745
uniprot id: D1C734
names: Similarity
messages: Belongs to the OsmC/Ohr family.

479434:STHE RS16585
gene id: 479434:STHE_RS16585
uniprot id: D1CA77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479434:STHE RS10215
gene id: 479434:STHE_RS10215
uniprot id: D1C5Q6
names: Similarity
messages: Belongs to the peptidase M16 family.

479434:STHE RS03035
gene id: 479434:STHE_RS03035
uniprot id: D1C1D2
names: Similarity
messages: Belongs to the peptidase S1C family.

479434:STHE RS02780
gene id: 479434:STHE_RS02780
uniprot id: D1C181
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

479434:STHE RS01080
gene id: 479434:STHE_RS01080
uniprot id: D1C6C0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS14055
gene id: 479434:STHE_RS14055
uniprot id: D1C8S6
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

479434:STHE RS15330
gene id: 479434:STHE_RS15330
uniprot id: D1C9H2
names: Similarity
messages: Belongs to the universal stress protein A family.

479434:STHE RS05720
gene id: 479434:STHE_RS05720
uniprot id: D1C2V9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

479434:STHE RS09245
gene id: 479434:STHE_RS09245
uniprot id: D1C4U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

479434:STHE RS02115
gene id: 479434:STHE_RS02115
uniprot id: D1C7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479434:STHE RS13290
gene id: 479434:STHE_RS13290
uniprot id: D1C8C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

479434:STHE RS14705
gene id: 479434:STHE_RS14705
uniprot id: D1C948
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

479434:STHE RS06785
gene id: 479434:STHE_RS06785
uniprot id: D1C3G3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

479434:STHE RS05225
gene id: 479434:STHE_RS05225
uniprot id: D1C2L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

479434:STHE RS06845
gene id: 479434:STHE_RS06845
uniprot id: D1C3H3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

479434:STHE RS10140
gene id: 479434:STHE_RS10140
uniprot id: D1C5P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

479434:STHE RS03555
gene id: 479434:STHE_RS03555
uniprot id: D1C1N6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

479434:STHE RS04835
gene id: 479434:STHE_RS04835
uniprot id: D1C2D2
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS05155
gene id: 479434:STHE_RS05155
uniprot id: D1C2J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

479434:STHE RS00750
gene id: 479434:STHE_RS00750
uniprot id: D1C654
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

479434:STHE RS00200
gene id: 479434:STHE_RS00200
uniprot id: D1C5G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

479434:STHE RS05985
gene id: 479434:STHE_RS05985
uniprot id: D1C310
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

479434:STHE RS11875
gene id: 479434:STHE_RS11875
uniprot id: D1C7E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

479434:STHE RS16840
gene id: 479434:STHE_RS16840
uniprot id: D1CAD1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS17135
gene id: 479434:STHE_RS17135
uniprot id: D1CAI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

479434:STHE RS13560
gene id: 479434:STHE_RS13560
uniprot id: D1C8H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS02380
gene id: 479434:STHE_RS02380
uniprot id: D1C7T9
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS12160
gene id: 479434:STHE_RS12160
uniprot id: D1C7X0
names: Subcellular Location Annotation
messages: Mitochondrion

479434:STHE RS03815
gene id: 479434:STHE_RS03815
uniprot id: D1C1T6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

479434:STHE RS06415
gene id: 479434:STHE_RS06415
uniprot id: D1C394
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

479434:STHE RS08710
gene id: 479434:STHE_RS08710
uniprot id: D1C4I7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

479434:STHE RS00365
gene id: 479434:STHE_RS00365
uniprot id: D1C5J8
names: Similarity
messages: Belongs to the AHA1 family.

479434:STHE RS08275
gene id: 479434:STHE_RS08275
uniprot id: D1C499
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

479434:STHE RS17350
gene id: 479434:STHE_RS17350
uniprot id: D1CAN1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

479434:STHE RS06215
gene id: 479434:STHE_RS06215
uniprot id: D1C356
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

479434:STHE RS01460
gene id: 479434:STHE_RS01460
uniprot id: D1C6X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

479434:STHE RS18680
gene id: 479434:STHE_RS18680
uniprot id: D1C128
names: Similarity
messages: Belongs to the TPP enzyme family.

479434:STHE RS19290
gene id: 479434:STHE_RS19290
uniprot id: D1C5C6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

479434:STHE RS10930
gene id: 479434:STHE_RS10930
uniprot id: D1C6H4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

479434:STHE RS08665
gene id: 479434:STHE_RS08665
uniprot id: D1C4H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

479434:STHE RS02170
gene id: 479434:STHE_RS02170
uniprot id: D1C7P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

479434:STHE RS09195
gene id: 479434:STHE_RS09195
uniprot id: D1C4T5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

479434:STHE RS11025
gene id: 479434:STHE_RS11025
uniprot id: D1C6J1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS08800
gene id: 479434:STHE_RS08800
uniprot id: D1C4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

479434:STHE RS05305
gene id: 479434:STHE_RS05305
uniprot id: D1C2M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

479434:STHE RS06285
gene id: 479434:STHE_RS06285
uniprot id: D1C370
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

479434:STHE RS03925
gene id: 479434:STHE_RS03925
uniprot id: D1C1V5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

479434:STHE RS06315
gene id: 479434:STHE_RS06315
uniprot id: D1C376
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

479434:STHE RS02145
gene id: 479434:STHE_RS02145
uniprot id: D1C7P2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

479434:STHE RS09205
gene id: 479434:STHE_RS09205
uniprot id: D1C4T7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

479434:STHE RS16085
gene id: 479434:STHE_RS16085
uniprot id: D1C9X4
names: Similarity
messages: Belongs to the peptidase S1C family.

479434:STHE RS00640
gene id: 479434:STHE_RS00640
uniprot id: D1C631
names: Similarity
messages: Belongs to the peptidase M20A family.

479434:STHE RS07040
gene id: 479434:STHE_RS07040
uniprot id: D1C3L0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

479434:STHE RS09405
gene id: 479434:STHE_RS09405
uniprot id: D1C4X7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS03060
gene id: 479434:STHE_RS03060
uniprot id: D1C1D7
names: Similarity
messages: Belongs to the UPF0047 family.

479434:STHE RS07720
gene id: 479434:STHE_RS07720
uniprot id: D1C3Z9
names: Similarity
messages: Belongs to the intimin/invasin family.

479434:STHE RS14310
gene id: 479434:STHE_RS14310
uniprot id: D1C8X5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

479434:STHE RS04235
gene id: 479434:STHE_RS04235
uniprot id: D1C218
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS02420
gene id: 479434:STHE_RS02420
uniprot id: D1C7U8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

479434:STHE RS04345
gene id: 479434:STHE_RS04345
uniprot id: D1C239
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

479434:STHE RS12500
gene id: 479434:STHE_RS12500
uniprot id: D1CAW5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

479434:STHE RS17840
gene id: 479434:STHE_RS17840
uniprot id: D1C2W2
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS08625
gene id: 479434:STHE_RS08625
uniprot id: D1C4H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

479434:STHE RS08505
gene id: 479434:STHE_RS08505
uniprot id: D1C4E7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

479434:STHE RS04895
gene id: 479434:STHE_RS04895
uniprot id: D1C2E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS08920
gene id: 479434:STHE_RS08920
uniprot id: D1C4N0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

479434:STHE RS15045
gene id: 479434:STHE_RS15045
uniprot id: D1C9B4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

479434:STHE RS10870
gene id: 479434:STHE_RS10870
uniprot id: D1C6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

479434:STHE RS10755
gene id: 479434:STHE_RS10755
uniprot id: D1C612
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479434:STHE RS02970
gene id: 479434:STHE_RS02970
uniprot id: D1C1B9
names: Similarity
messages: Belongs to the DinB family.

479434:STHE RS09110
gene id: 479434:STHE_RS09110
uniprot id: D1C4R8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

479434:STHE RS01445
gene id: 479434:STHE_RS01445
uniprot id: D1C6X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

479434:STHE RS06725
gene id: 479434:STHE_RS06725
uniprot id: D1C3F0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

479434:STHE RS07185
gene id: 479434:STHE_RS07185
uniprot id: D1C3N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

479434:STHE RS00795
gene id: 479434:STHE_RS00795
uniprot id: D1C663
names: Similarity
messages: Belongs to the peptidase S8 family.

479434:STHE RS10135
gene id: 479434:STHE_RS10135
uniprot id: D1C5N9
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

479434:STHE RS00145
gene id: 479434:STHE_RS00145
uniprot id: D1C5F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

479434:STHE RS03505
gene id: 479434:STHE_RS03505
uniprot id: D1C1M6
names: Similarity
messages: Belongs to the ycf81 family.

479434:STHE RS09785
gene id: 479434:STHE_RS09785
uniprot id: D1C553
names: Similarity
messages: Belongs to the pyruvate kinase family.

479434:STHE RS02760
gene id: 479434:STHE_RS02760
uniprot id: D1C177
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

479434:STHE RS15235
gene id: 479434:STHE_RS15235
uniprot id: D1C9F2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

479434:STHE RS12840
gene id: 479434:STHE_RS12840
uniprot id: D1C837
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

479434:STHE RS15070
gene id: 479434:STHE_RS15070
uniprot id: D1C9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

479434:STHE RS09675
gene id: 479434:STHE_RS09675
uniprot id: D1C531
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS17175
gene id: 479434:STHE_RS17175
uniprot id: D1CAJ6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

479434:STHE RS17735
gene id: 479434:STHE_RS17735
uniprot id: D1C1A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

479434:STHE RS10300
gene id: 479434:STHE_RS10300
uniprot id: D1C5S3
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

479434:STHE RS02455
gene id: 479434:STHE_RS02455
uniprot id: D1C121
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

479434:STHE RS07175
gene id: 479434:STHE_RS07175
uniprot id: D1C3N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS15100
gene id: 479434:STHE_RS15100
uniprot id: D1C9C5
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

479434:STHE RS08180
gene id: 479434:STHE_RS08180
uniprot id: D1C480
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

479434:STHE RS11545
gene id: 479434:STHE_RS11545
uniprot id: D1C776
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

479434:STHE RS05815
gene id: 479434:STHE_RS05815
uniprot id: D1C2X6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

479434:STHE RS14645
gene id: 479434:STHE_RS14645
uniprot id: D1C936
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

479434:STHE RS17080
gene id: 479434:STHE_RS17080
uniprot id: D1CAH7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

479434:STHE RS04075
gene id: 479434:STHE_RS04075
uniprot id: D1C1Y5
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS05915
gene id: 479434:STHE_RS05915
uniprot id: D1C2Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

479434:STHE RS09925
gene id: 479434:STHE_RS09925
uniprot id: D1C581
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

479434:STHE RS09325
gene id: 479434:STHE_RS09325
uniprot id: D1C4W1
names: Similarity
messages: Belongs to the sigma-54 factor family.

479434:STHE RS12495
gene id: 479434:STHE_RS12495
uniprot id: D1CAW4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

479434:STHE RS14510
gene id: 479434:STHE_RS14510
uniprot id: D1C915
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

479434:STHE RS03605
gene id: 479434:STHE_RS03605
uniprot id: D1C1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

479434:STHE RS07225
gene id: 479434:STHE_RS07225
uniprot id: D1C3P7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS02810
gene id: 479434:STHE_RS02810
uniprot id: D1C187
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

479434:STHE RS16850
gene id: 479434:STHE_RS16850
uniprot id: D1CAD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

479434:STHE RS12430
gene id: 479434:STHE_RS12430
uniprot id: D1CAV1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07625
gene id: 479434:STHE_RS07625
uniprot id: D1C3Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS05950
gene id: 479434:STHE_RS05950
uniprot id: D1C303
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

479434:STHE RS03520
gene id: 479434:STHE_RS03520
uniprot id: D1C1M9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

479434:STHE RS09105
gene id: 479434:STHE_RS09105
uniprot id: D1C4R7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

479434:STHE RS05065
gene id: 479434:STHE_RS05065
uniprot id: D1C2H8
names: Similarity
messages: Belongs to the TPP enzyme family.

479434:STHE RS00280
gene id: 479434:STHE_RS00280
uniprot id: D1C5I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS17380
gene id: 479434:STHE_RS17380
uniprot id: D1CAN7
names: Similarity
messages: Belongs to the citrate synthase family.

479434:STHE RS00235
gene id: 479434:STHE_RS00235
uniprot id: D1C5H1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479434:STHE RS09560
gene id: 479434:STHE_RS09560
uniprot id: D1C508
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS00285
gene id: 479434:STHE_RS00285
uniprot id: D1C5I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS01685
gene id: 479434:STHE_RS01685
uniprot id: D1C722
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

479434:STHE RS14045
gene id: 479434:STHE_RS14045
uniprot id: D1C8S4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479434:STHE RS05295
gene id: 479434:STHE_RS05295
uniprot id: D1C2M6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

479434:STHE RS02685
gene id: 479434:STHE_RS02685
uniprot id: D1C162
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

479434:STHE RS08060
gene id: 479434:STHE_RS08060
uniprot id: D1C460
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

479434:STHE RS09415
gene id: 479434:STHE_RS09415
uniprot id: D1C4X9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

479434:STHE RS07015
gene id: 479434:STHE_RS07015
uniprot id: D1C3K5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

479434:STHE RS17060
gene id: 479434:STHE_RS17060
uniprot id: D1CAH4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

479434:STHE RS17165
gene id: 479434:STHE_RS17165
uniprot id: D1CAJ4
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

479434:STHE RS08455
gene id: 479434:STHE_RS08455
uniprot id: D1C4D6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

479434:STHE RS08125
gene id: 479434:STHE_RS08125
uniprot id: D1C472
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

479434:STHE RS00540
gene id: 479434:STHE_RS00540
uniprot id: D1C5N3
names: Similarity
messages: Belongs to the DinB family.

479434:STHE RS04465
gene id: 479434:STHE_RS04465
uniprot id: D1C261
names: Similarity
messages: Belongs to the CinA family.

479434:STHE RS12760
gene id: 479434:STHE_RS12760
uniprot id: D1C821
names: Similarity
messages: Belongs to the peptidase S8 family.

479434:STHE RS16635
gene id: 479434:STHE_RS16635
uniprot id: D1CA87
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

479434:STHE RS09085
gene id: 479434:STHE_RS09085
uniprot id: D1C4R3
names: Similarity
messages: Belongs to the DSD1 family.

479434:STHE RS04125
gene id: 479434:STHE_RS04125
uniprot id: D1C1Z6
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

479434:STHE RS14965
gene id: 479434:STHE_RS14965
uniprot id: D1C998
names: Subunit
messages: Homodimer.

479434:STHE RS09345
gene id: 479434:STHE_RS09345
uniprot id: D1C4W5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

479434:STHE RS06990
gene id: 479434:STHE_RS06990
uniprot id: D1C3K0
names: Similarity
messages: Belongs to the BtpA family.

479434:STHE RS16020
gene id: 479434:STHE_RS16020
uniprot id: D1C9W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

479434:STHE RS14555
gene id: 479434:STHE_RS14555
uniprot id: D1C924
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479434:STHE RS06745
gene id: 479434:STHE_RS06745
uniprot id: D1C3F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

479434:STHE RS06645
gene id: 479434:STHE_RS06645
uniprot id: D1C3D7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS03130
gene id: 479434:STHE_RS03130
uniprot id: D1C1F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

479434:STHE RS15625
gene id: 479434:STHE_RS15625
uniprot id: D1C9N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

479434:STHE RS00830
gene id: 479434:STHE_RS00830
uniprot id: D1C670
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS08570
gene id: 479434:STHE_RS08570
uniprot id: D1C4G0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

479434:STHE RS17795
gene id: 479434:STHE_RS17795
uniprot id: D1C1U5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

479434:STHE RS16145
gene id: 479434:STHE_RS16145
uniprot id: D1C9Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS05860
gene id: 479434:STHE_RS05860
uniprot id: D1C2Y5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

479434:STHE RS16255
gene id: 479434:STHE_RS16255
uniprot id: D1CA08
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

479434:STHE RS13535
gene id: 479434:STHE_RS13535
uniprot id: D1C8H3
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS14900
gene id: 479434:STHE_RS14900
uniprot id: D1C985
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479434:STHE RS08070
gene id: 479434:STHE_RS08070
uniprot id: D1C462
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

479434:STHE RS10545
gene id: 479434:STHE_RS10545
uniprot id: D1C5W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

479434:STHE RS04745
gene id: 479434:STHE_RS04745
uniprot id: D1C2B5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

479434:STHE RS02325
gene id: 479434:STHE_RS02325
uniprot id: D1C7S8
names: Similarity
messages: Belongs to the UPF0102 family.

479434:STHE RS00860
gene id: 479434:STHE_RS00860
uniprot id: D1C676
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479434:STHE RS12900
gene id: 479434:STHE_RS12900
uniprot id: D1C849
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

479434:STHE RS04025
gene id: 479434:STHE_RS04025
uniprot id: D1C1X5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479434:STHE RS07585
gene id: 479434:STHE_RS07585
uniprot id: D1C3X2
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS03510
gene id: 479434:STHE_RS03510
uniprot id: D1C1M7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

479434:STHE RS01865
gene id: 479434:STHE_RS01865
uniprot id: D1C7I6
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

479434:STHE RS15375
gene id: 479434:STHE_RS15375
uniprot id: D1C9I1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

479434:STHE RS05535
gene id: 479434:STHE_RS05535
uniprot id: D1C2S3
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

479434:STHE RS00710
gene id: 479434:STHE_RS00710
uniprot id: D1C646
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

479434:STHE RS15220
gene id: 479434:STHE_RS15220
uniprot id: D1C9E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS01455
gene id: 479434:STHE_RS01455
uniprot id: D1C6X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479434:STHE RS02280
gene id: 479434:STHE_RS02280
uniprot id: D1C7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

479434:STHE RS13755
gene id: 479434:STHE_RS13755
uniprot id: D1C8L6
names: Similarity
messages: Belongs to the LOG family.

479434:STHE RS03415
gene id: 479434:STHE_RS03415
uniprot id: D1C1K8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

479434:STHE RS10650
gene id: 479434:STHE_RS10650
uniprot id: D1C5Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

479434:STHE RS05320
gene id: 479434:STHE_RS05320
uniprot id: D1C2N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

479434:STHE RS05290
gene id: 479434:STHE_RS05290
uniprot id: D1C2M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

479434:STHE RS08980
gene id: 479434:STHE_RS08980
uniprot id: D1C4P3
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07025
gene id: 479434:STHE_RS07025
uniprot id: D1C3K7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS13185
gene id: 479434:STHE_RS13185
uniprot id: D1C8A2
names: Cofactor
messages: Binds 1 FAD per subunit.

479434:STHE RS09420
gene id: 479434:STHE_RS09420
uniprot id: D1C4Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

479434:STHE RS04740
gene id: 479434:STHE_RS04740
uniprot id: D1C2B4
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

479434:STHE RS05080
gene id: 479434:STHE_RS05080
uniprot id: D1C2I1
names: Similarity
messages: Belongs to the creatininase superfamily.

479434:STHE RS09280
gene id: 479434:STHE_RS09280
uniprot id: D1C4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

479434:STHE RS07975
gene id: 479434:STHE_RS07975
uniprot id: D1C446
names: Similarity
messages: Belongs to the RutC family.

479434:STHE RS06965
gene id: 479434:STHE_RS06965
uniprot id: D1C3J5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

479434:STHE RS11945
gene id: 479434:STHE_RS11945
uniprot id: D1C7F3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

479434:STHE RS05310
gene id: 479434:STHE_RS05310
uniprot id: D1C2M9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

479434:STHE RS15465
gene id: 479434:STHE_RS15465
uniprot id: D1C9J8
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS00400
gene id: 479434:STHE_RS00400
uniprot id: D1C5K4
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

479434:STHE RS11045
gene id: 479434:STHE_RS11045
uniprot id: D1C6J5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

479434:STHE RS04730
gene id: 479434:STHE_RS04730
uniprot id: D1C2B2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

479434:STHE RS06775
gene id: 479434:STHE_RS06775
uniprot id: D1C3G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS17460
gene id: 479434:STHE_RS17460
uniprot id: D1CAQ3
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07180
gene id: 479434:STHE_RS07180
uniprot id: D1C3N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

479434:STHE RS15845
gene id: 479434:STHE_RS15845
uniprot id: D1C9S5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

479434:STHE RS10380
gene id: 479434:STHE_RS10380
uniprot id: D1C5U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

479434:STHE RS04910
gene id: 479434:STHE_RS04910
uniprot id: D1C2E7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

479434:STHE RS08310
gene id: 479434:STHE_RS08310
uniprot id: D1C4A6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS07685
gene id: 479434:STHE_RS07685
uniprot id: D1C3Z2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

479434:STHE RS05555
gene id: 479434:STHE_RS05555
uniprot id: D1C2S7
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

479434:STHE RS08320
gene id: 479434:STHE_RS08320
uniprot id: D1C4A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

479434:STHE RS15545
gene id: 479434:STHE_RS15545
uniprot id: D1C9L4
names: Similarity
messages: Belongs to the ketopantoate reductase family.

479434:STHE RS05690
gene id: 479434:STHE_RS05690
uniprot id: D1C2V3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

479434:STHE RS02560
gene id: 479434:STHE_RS02560
uniprot id: D1C137
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

479434:STHE RS05885
gene id: 479434:STHE_RS05885
uniprot id: D1C2Z0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

479434:STHE RS04410
gene id: 479434:STHE_RS04410
uniprot id: D1C252
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

479434:STHE RS10055
gene id: 479434:STHE_RS10055
uniprot id: D1C5A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

479434:STHE RS16240
gene id: 479434:STHE_RS16240
uniprot id: D1CA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

479434:STHE RS14915
gene id: 479434:STHE_RS14915
uniprot id: D1C988
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

479434:STHE RS16815
gene id: 479434:STHE_RS16815
uniprot id: D1CAC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS00395
gene id: 479434:STHE_RS00395
uniprot id: D1C5K3
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS16575
gene id: 479434:STHE_RS16575
uniprot id: D1CA75
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS05980
gene id: 479434:STHE_RS05980
uniprot id: D1C309
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS10790
gene id: 479434:STHE_RS10790
uniprot id: D1C6E6
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS17760
gene id: 479434:STHE_RS17760
uniprot id: D1C1N8
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS09475
gene id: 479434:STHE_RS09475
uniprot id: D1C4Z1
names: Similarity
messages: Belongs to the TrpC family.

479434:STHE RS14115
gene id: 479434:STHE_RS14115
uniprot id: D1C8T8
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

479434:STHE RS15595
gene id: 479434:STHE_RS15595
uniprot id: D1C9M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

479434:STHE RS15560
gene id: 479434:STHE_RS15560
uniprot id: D1C9L8
names: Similarity
messages: Belongs to the leucine-binding protein family.

479434:STHE RS10050
gene id: 479434:STHE_RS10050
uniprot id: D1C5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

479434:STHE RS00070
gene id: 479434:STHE_RS00070
uniprot id: D1C5D7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS13820
gene id: 479434:STHE_RS13820
uniprot id: D1C8M9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

479434:STHE RS00700
gene id: 479434:STHE_RS00700
uniprot id: D1C644
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS11100
gene id: 479434:STHE_RS11100
uniprot id: D1C6K6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

479434:STHE RS11110
gene id: 479434:STHE_RS11110
uniprot id: D1C6K8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

479434:STHE RS14640
gene id: 479434:STHE_RS14640
uniprot id: D1C935
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479434:STHE RS01700
gene id: 479434:STHE_RS01700
uniprot id: D1C725
names: Similarity
messages: Belongs to the UPF0758 family.

479434:STHE RS00165
gene id: 479434:STHE_RS00165
uniprot id: D1C5F7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

479434:STHE RS03320
gene id: 479434:STHE_RS03320
uniprot id: D1C1J0
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07130
gene id: 479434:STHE_RS07130
uniprot id: D1C3M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

479434:STHE RS13390
gene id: 479434:STHE_RS13390
uniprot id: D1C8E5
names: Similarity
messages: Belongs to the aspartokinase family.

479434:STHE RS01775
gene id: 479434:STHE_RS01775
uniprot id: D1C740
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

479434:STHE RS12600
gene id: 479434:STHE_RS12600
uniprot id: D1CAY5
names: Similarity
messages: Belongs to the peptidase M20A family.

479434:STHE RS08500
gene id: 479434:STHE_RS08500
uniprot id: D1C4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479434:STHE RS05580
gene id: 479434:STHE_RS05580
uniprot id: D1C2T1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

479434:STHE RS01545
gene id: 479434:STHE_RS01545
uniprot id: D1C6Z4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

479434:STHE RS15610
gene id: 479434:STHE_RS15610
uniprot id: D1C9M8
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

479434:STHE RS09750
gene id: 479434:STHE_RS09750
uniprot id: D1C546
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

479434:STHE RS13470
gene id: 479434:STHE_RS13470
uniprot id: D1C8G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

479434:STHE RS05115
gene id: 479434:STHE_RS05115
uniprot id: D1C2I9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

479434:STHE RS07820
gene id: 479434:STHE_RS07820
uniprot id: D1C419
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

479434:STHE RS17520
gene id: 479434:STHE_RS17520
uniprot id: D1CAR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

479434:STHE RS15660
gene id: 479434:STHE_RS15660
uniprot id: D1C9N8
names: Similarity
messages: Belongs to the UPF0111 family.

479434:STHE RS19200
gene id: 479434:STHE_RS19200
uniprot id: D1C3T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS05235
gene id: 479434:STHE_RS05235
uniprot id: D1C2L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

479434:STHE RS10810
gene id: 479434:STHE_RS10810
uniprot id: D1C6F0
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS02855
gene id: 479434:STHE_RS02855
uniprot id: D1C197
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

479434:STHE RS07805
gene id: 479434:STHE_RS07805
uniprot id: D1C416
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

479434:STHE RS02015
gene id: 479434:STHE_RS02015
uniprot id: D1C7L6
names: Similarity
messages: Belongs to the YggT family.

479434:STHE RS03215
gene id: 479434:STHE_RS03215
uniprot id: D1C1H0
names: Similarity
messages: Belongs to the citrate synthase family.

479434:STHE RS03190
gene id: 479434:STHE_RS03190
uniprot id: D1C1G5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

479434:STHE RS11905
gene id: 479434:STHE_RS11905
uniprot id: D1C7E7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

479434:STHE RS13635
gene id: 479434:STHE_RS13635
uniprot id: D1C8J2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

479434:STHE RS16140
gene id: 479434:STHE_RS16140
uniprot id: D1C9Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS12395
gene id: 479434:STHE_RS12395
uniprot id: D1CAU4
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

479434:STHE RS06765
gene id: 479434:STHE_RS06765
uniprot id: D1C3F9
names: Similarity
messages: Belongs to the selenium-binding protein family.

479434:STHE RS05200
gene id: 479434:STHE_RS05200
uniprot id: D1C2K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

479434:STHE RS12365
gene id: 479434:STHE_RS12365
uniprot id: D1CAT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

479434:STHE RS00620
gene id: 479434:STHE_RS00620
uniprot id: D1C627
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

479434:STHE RS00140
gene id: 479434:STHE_RS00140
uniprot id: D1C5F1
names: Similarity
messages: Belongs to the class-I fumarase family.

479434:STHE RS06735
gene id: 479434:STHE_RS06735
uniprot id: D1C3F2
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS12730
gene id: 479434:STHE_RS12730
uniprot id: D1C815
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

479434:STHE RS08870
gene id: 479434:STHE_RS08870
uniprot id: D1C4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

479434:STHE RS05650
gene id: 479434:STHE_RS05650
uniprot id: D1C2U5
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

479434:STHE RS08120
gene id: 479434:STHE_RS08120
uniprot id: D1C471
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

479434:STHE RS10255
gene id: 479434:STHE_RS10255
uniprot id: D1C5R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

479434:STHE RS07265
gene id: 479434:STHE_RS07265
uniprot id: D1C3Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

479434:STHE RS17690
gene id: 479434:STHE_RS17690
uniprot id: D1C7P1
names: Similarity
messages: Belongs to the peptidase S11 family.

479434:STHE RS02440
gene id: 479434:STHE_RS02440
uniprot id: D1C7V2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

479434:STHE RS08545
gene id: 479434:STHE_RS08545
uniprot id: D1C4F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates ribosomal protein L11.

479434:STHE RS14780
gene id: 479434:STHE_RS14780
uniprot id: D1C961
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

479434:STHE RS03470
gene id: 479434:STHE_RS03470
uniprot id: D1C1L9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

479434:STHE RS05300
gene id: 479434:STHE_RS05300
uniprot id: D1C2M7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

479434:STHE RS14715
gene id: 479434:STHE_RS14715
uniprot id: D1C950
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

479434:STHE RS00340
gene id: 479434:STHE_RS00340
uniprot id: D1C5J3
names: Similarity
messages: Belongs to the class-I fumarase family.

479434:STHE RS14505
gene id: 479434:STHE_RS14505
uniprot id: D1C914
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS17820
gene id: 479434:STHE_RS17820
uniprot id: D1C299
names: Similarity
messages: Belongs to the terpene synthase family.

479434:STHE RS15600
gene id: 479434:STHE_RS15600
uniprot id: D1C9M6
names: Subcellular Location Annotation
messages: Cytoplasm

479434:STHE RS05900
gene id: 479434:STHE_RS05900
uniprot id: D1C2Z3
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS15650
gene id: 479434:STHE_RS15650
uniprot id: D1C9N6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479434:STHE RS10075
gene id: 479434:STHE_RS10075
uniprot id: D1C5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

479434:STHE RS12265
gene id: 479434:STHE_RS12265
uniprot id: D1C7Z3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS00330
gene id: 479434:STHE_RS00330
uniprot id: D1C5J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

479434:STHE RS00385
gene id: 479434:STHE_RS00385
uniprot id: D1C5K1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS10670
gene id: 479434:STHE_RS10670
uniprot id: D1C5Z5
names: Similarity
messages: Belongs to the HypE family.

479434:STHE RS12490
gene id: 479434:STHE_RS12490
uniprot id: D1CAW2
names: Similarity
messages: Belongs to the peptidase A31 family.

479434:STHE RS04315
gene id: 479434:STHE_RS04315
uniprot id: D1C233
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

479434:STHE RS15750
gene id: 479434:STHE_RS15750
uniprot id: D1C9Q6
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

479434:STHE RS01790
gene id: 479434:STHE_RS01790
uniprot id: D1C743
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

479434:STHE RS01770
gene id: 479434:STHE_RS01770
uniprot id: D1C739
names: Similarity
messages: Belongs to the YciI family.

479434:STHE RS09340
gene id: 479434:STHE_RS09340
uniprot id: D1C4W4
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS16210
gene id: 479434:STHE_RS16210
uniprot id: D1C9Z9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

479434:STHE RS06455
gene id: 479434:STHE_RS06455
uniprot id: D1C3A0
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS09590
gene id: 479434:STHE_RS09590
uniprot id: D1C514
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

479434:STHE RS08955
gene id: 479434:STHE_RS08955
uniprot id: D1C4N7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

479434:STHE RS17320
gene id: 479434:STHE_RS17320
uniprot id: D1CAM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

479434:STHE RS13445
gene id: 479434:STHE_RS13445
uniprot id: D1C8F5
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS11530
gene id: 479434:STHE_RS11530
uniprot id: D1C773
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

479434:STHE RS11080
gene id: 479434:STHE_RS11080
uniprot id: D1C6K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS04105
gene id: 479434:STHE_RS04105
uniprot id: D1C1Z1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479434:STHE RS10815
gene id: 479434:STHE_RS10815
uniprot id: D1C6F1
names: Similarity
messages: Belongs to the leucine-binding protein family.

479434:STHE RS05345
gene id: 479434:STHE_RS05345
uniprot id: D1C2N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

479434:STHE RS13960
gene id: 479434:STHE_RS13960
uniprot id: D1C8Q6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS09945
gene id: 479434:STHE_RS09945
uniprot id: D1C585
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

479434:STHE RS02835
gene id: 479434:STHE_RS02835
uniprot id: D1C193
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

479434:STHE RS17570
gene id: 479434:STHE_RS17570
uniprot id: D1CAS5
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

479434:STHE RS01555
gene id: 479434:STHE_RS01555
uniprot id: D1C6Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

479434:STHE RS17365
gene id: 479434:STHE_RS17365
uniprot id: D1CAN4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

479434:STHE RS01850
gene id: 479434:STHE_RS01850
uniprot id: D1C7I3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

479434:STHE RS14345
gene id: 479434:STHE_RS14345
uniprot id: D1C8Y2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479434:STHE RS12835
gene id: 479434:STHE_RS12835
uniprot id: D1C836
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS09115
gene id: 479434:STHE_RS09115
uniprot id: D1C4R9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

479434:STHE RS04930
gene id: 479434:STHE_RS04930
uniprot id: D1C2F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

479434:STHE RS09100
gene id: 479434:STHE_RS09100
uniprot id: D1C4R6
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

479434:STHE RS08525
gene id: 479434:STHE_RS08525
uniprot id: D1C4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

479434:STHE RS05840
gene id: 479434:STHE_RS05840
uniprot id: D1C2Y1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS05185
gene id: 479434:STHE_RS05185
uniprot id: D1C2K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

479434:STHE RS06265
gene id: 479434:STHE_RS06265
uniprot id: D1C366
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

479434:STHE RS09865
gene id: 479434:STHE_RS09865
uniprot id: D1C569
names: Similarity
messages: Belongs to the peptidase M20A family.

479434:STHE RS06545
gene id: 479434:STHE_RS06545
uniprot id: D1C3B8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

479434:STHE RS16645
gene id: 479434:STHE_RS16645
uniprot id: D1CA89
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS02255
gene id: 479434:STHE_RS02255
uniprot id: D1C7R4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

479434:STHE RS08130
gene id: 479434:STHE_RS08130
uniprot id: D1C473
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

479434:STHE RS09835
gene id: 479434:STHE_RS09835
uniprot id: D1C563
names: Similarity
messages: Belongs to the peptidase S9C family.

479434:STHE RS06970
gene id: 479434:STHE_RS06970
uniprot id: D1C3J6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

479434:STHE RS05165
gene id: 479434:STHE_RS05165
uniprot id: D1C2K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

479434:STHE RS07290
gene id: 479434:STHE_RS07290
uniprot id: D1C3R0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

479434:STHE RS08635
gene id: 479434:STHE_RS08635
uniprot id: D1C4H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

479434:STHE RS01030
gene id: 479434:STHE_RS01030
uniprot id: D1C6B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

479434:STHE RS03650
gene id: 479434:STHE_RS03650
uniprot id: D1C1Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

479434:STHE RS17785
gene id: 479434:STHE_RS17785
uniprot id: D1C1S6
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS13980
gene id: 479434:STHE_RS13980
uniprot id: D1C8R0
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS08225
gene id: 479434:STHE_RS08225
uniprot id: D1C490
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS09860
gene id: 479434:STHE_RS09860
uniprot id: D1C568
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

479434:STHE RS07815
gene id: 479434:STHE_RS07815
uniprot id: D1C418
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS13375
gene id: 479434:STHE_RS13375
uniprot id: D1C8E1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS02270
gene id: 479434:STHE_RS02270
uniprot id: D1C7R7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

479434:STHE RS01955
gene id: 479434:STHE_RS01955
uniprot id: D1C7K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

479434:STHE RS15495
gene id: 479434:STHE_RS15495
uniprot id: D1C9K5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

479434:STHE RS02060
gene id: 479434:STHE_RS02060
uniprot id: D1C7M5
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS01570
gene id: 479434:STHE_RS01570
uniprot id: D1C6Z9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

479434:STHE RS07325
gene id: 479434:STHE_RS07325
uniprot id: D1C3R8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS03645
gene id: 479434:STHE_RS03645
uniprot id: D1C1Q4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

479434:STHE RS10840
gene id: 479434:STHE_RS10840
uniprot id: D1C6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

479434:STHE RS04135
gene id: 479434:STHE_RS04135
uniprot id: D1C1Z8
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS15115
gene id: 479434:STHE_RS15115
uniprot id: D1C9C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

479434:STHE RS04800
gene id: 479434:STHE_RS04800
uniprot id: D1C2C6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

479434:STHE RS04145
gene id: 479434:STHE_RS04145
uniprot id: D1C200
names: Similarity
messages: Belongs to the peptidase M20A family.

479434:STHE RS05325
gene id: 479434:STHE_RS05325
uniprot id: D1C2N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

479434:STHE RS05025
gene id: 479434:STHE_RS05025
uniprot id: D1C2H0
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

479434:STHE RS01465
gene id: 479434:STHE_RS01465
uniprot id: D1C6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

479434:STHE RS04375
gene id: 479434:STHE_RS04375
uniprot id: D1C245
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

479434:STHE RS13540
gene id: 479434:STHE_RS13540
uniprot id: D1C8H4
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS06300
gene id: 479434:STHE_RS06300
uniprot id: D1C373
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

479434:STHE RS02400
gene id: 479434:STHE_RS02400
uniprot id: D1C7U3
names: Similarity
messages: Belongs to the DapA family.

479434:STHE RS10080
gene id: 479434:STHE_RS10080
uniprot id: D1C5B2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

479434:STHE RS05550
gene id: 479434:STHE_RS05550
uniprot id: D1C2S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

479434:STHE RS17280
gene id: 479434:STHE_RS17280
uniprot id: D1CAL7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS16090
gene id: 479434:STHE_RS16090
uniprot id: D1C9X5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS08950
gene id: 479434:STHE_RS08950
uniprot id: D1C4N6
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS08990
gene id: 479434:STHE_RS08990
uniprot id: D1C4P5
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS02135
gene id: 479434:STHE_RS02135
uniprot id: D1C7P0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

479434:STHE RS05910
gene id: 479434:STHE_RS05910
uniprot id: D1C2Z5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

479434:STHE RS02990
gene id: 479434:STHE_RS02990
uniprot id: D1C1C3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

479434:STHE RS08810
gene id: 479434:STHE_RS08810
uniprot id: D1C4K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

479434:STHE RS13615
gene id: 479434:STHE_RS13615
uniprot id: D1C8I8
names: Similarity
messages: Belongs to the IlvD/Edd family.

479434:STHE RS02730
gene id: 479434:STHE_RS02730
uniprot id: D1C171
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

479434:STHE RS06640
gene id: 479434:STHE_RS06640
uniprot id: D1C3D6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

479434:STHE RS10630
gene id: 479434:STHE_RS10630
uniprot id: D1C5Y6
names: Similarity
messages: Belongs to the intimin/invasin family.

479434:STHE RS06610
gene id: 479434:STHE_RS06610
uniprot id: D1C3D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

479434:STHE RS05445
gene id: 479434:STHE_RS05445
uniprot id: D1C2Q6
names: Similarity
messages: Belongs to the PspA/IM30 family.

479434:STHE RS15085
gene id: 479434:STHE_RS15085
uniprot id: D1C9C2
names: Cofactor
messages: Divalent metal ions. Mg(2+) is the most effective.

479434:STHE RS13150
gene id: 479434:STHE_RS13150
uniprot id: D1C895
names: Similarity
messages: Belongs to the glutamine synthetase family.

479434:STHE RS17095
gene id: 479434:STHE_RS17095
uniprot id: D1CAI0
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

479434:STHE RS11805
gene id: 479434:STHE_RS11805
uniprot id: D1C7C8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479434:STHE RS07395
gene id: 479434:STHE_RS07395
uniprot id: D1C3T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

479434:STHE RS15980
gene id: 479434:STHE_RS15980
uniprot id: D1C9V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

479434:STHE RS08375
gene id: 479434:STHE_RS08375
uniprot id: D1C4B9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479434:STHE RS10355
gene id: 479434:STHE_RS10355
uniprot id: D1C5T5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

479434:STHE RS13610
gene id: 479434:STHE_RS13610
uniprot id: D1C8I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS19020
gene id: 479434:STHE_RS19020
uniprot id: D1C550
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

479434:STHE RS14975
gene id: 479434:STHE_RS14975
uniprot id: D1C9A0
names: Similarity
messages: Belongs to the asparaginase 1 family.

479434:STHE RS02890
gene id: 479434:STHE_RS02890
uniprot id: D1C1A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

479434:STHE RS02660
gene id: 479434:STHE_RS02660
uniprot id: D1C157
names: Similarity
messages: Belongs to the DinB family.

479434:STHE RS00920
gene id: 479434:STHE_RS00920
uniprot id: D1C688
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

479434:STHE RS03465
gene id: 479434:STHE_RS03465
uniprot id: D1C1L8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

479434:STHE RS13480
gene id: 479434:STHE_RS13480
uniprot id: D1C8G2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

479434:STHE RS16925
gene id: 479434:STHE_RS16925
uniprot id: D1CAE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

479434:STHE RS08245
gene id: 479434:STHE_RS08245
uniprot id: D1C494
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

479434:STHE RS00440
gene id: 479434:STHE_RS00440
uniprot id: D1C5L3
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07240
gene id: 479434:STHE_RS07240
uniprot id: D1C3Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

479434:STHE RS04725
gene id: 479434:STHE_RS04725
uniprot id: D1C2B1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

479434:STHE RS08620
gene id: 479434:STHE_RS08620
uniprot id: D1C4G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

479434:STHE RS08725
gene id: 479434:STHE_RS08725
uniprot id: D1C4J0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

479434:STHE RS02330
gene id: 479434:STHE_RS02330
uniprot id: D1C7S9
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

479434:STHE RS15450
gene id: 479434:STHE_RS15450
uniprot id: D1C9J5
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS06480
gene id: 479434:STHE_RS06480
uniprot id: D1C3A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

479434:STHE RS11920
gene id: 479434:STHE_RS11920
uniprot id: D1C7F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

479434:STHE RS09225
gene id: 479434:STHE_RS09225
uniprot id: D1C4U1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

479434:STHE RS12295
gene id: 479434:STHE_RS12295
uniprot id: D1C7Z9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

479434:STHE RS15430
gene id: 479434:STHE_RS15430
uniprot id: D1C9J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

479434:STHE RS03865
gene id: 479434:STHE_RS03865
uniprot id: D1C1U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

479434:STHE RS08360
gene id: 479434:STHE_RS08360
uniprot id: D1C4B6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

479434:STHE RS02040
gene id: 479434:STHE_RS02040
uniprot id: D1C7M1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

479434:STHE RS07205
gene id: 479434:STHE_RS07205
uniprot id: D1C3P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

479434:STHE RS05460
gene id: 479434:STHE_RS05460
uniprot id: D1C2Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

479434:STHE RS02710
gene id: 479434:STHE_RS02710
uniprot id: D1C167
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

479434:STHE RS03880
gene id: 479434:STHE_RS03880
uniprot id: D1C1U7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

479434:STHE RS05710
gene id: 479434:STHE_RS05710
uniprot id: D1C2V7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07880
gene id: 479434:STHE_RS07880
uniprot id: D1C428
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

479434:STHE RS05585
gene id: 479434:STHE_RS05585
uniprot id: D1C2T2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

479434:STHE RS17495
gene id: 479434:STHE_RS17495
uniprot id: D1CAR0
names: Similarity
messages: Belongs to the proline racemase family.

479434:STHE RS08460
gene id: 479434:STHE_RS08460
uniprot id: D1C4D7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

479434:STHE RS11135
gene id: 479434:STHE_RS11135
uniprot id: D1C6L3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS08480
gene id: 479434:STHE_RS08480
uniprot id: D1C4E2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

479434:STHE RS13735
gene id: 479434:STHE_RS13735
uniprot id: D1C8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

479434:STHE RS18270
gene id: 479434:STHE_RS18270
uniprot id: D1C9X8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

479434:STHE RS16750
gene id: 479434:STHE_RS16750
uniprot id: D1CAB3
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS10060
gene id: 479434:STHE_RS10060
uniprot id: D1C5A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS01595
gene id: 479434:STHE_RS01595
uniprot id: D1C704
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

479434:STHE RS11505
gene id: 479434:STHE_RS11505
uniprot id: D1C768
names: Similarity
messages: Belongs to the arginase family.

479434:STHE RS11935
gene id: 479434:STHE_RS11935
uniprot id: D1C7F1
names: Similarity
messages: Belongs to the DEAD box helicase family.

479434:STHE RS03960
gene id: 479434:STHE_RS03960
uniprot id: D1C1W2
names: Similarity
messages: Belongs to the peptidase M24B family.

479434:STHE RS01375
gene id: 479434:STHE_RS01375
uniprot id: D1C6V9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

479434:STHE RS04265
gene id: 479434:STHE_RS04265
uniprot id: D1C224
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

479434:STHE RS08145
gene id: 479434:STHE_RS08145
uniprot id: D1C476
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

479434:STHE RS04610
gene id: 479434:STHE_RS04610
uniprot id: D1C289
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

479434:STHE RS03350
gene id: 479434:STHE_RS03350
uniprot id: D1C1J5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479434:STHE RS04965
gene id: 479434:STHE_RS04965
uniprot id: D1C2F8
names: Similarity
messages: Belongs to the peptidase S9C family.

479434:STHE RS02770
gene id: 479434:STHE_RS02770
uniprot id: D1C179
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

479434:STHE RS14970
gene id: 479434:STHE_RS14970
uniprot id: D1C999
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS02035
gene id: 479434:STHE_RS02035
uniprot id: D1C7M0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

479434:STHE RS13775
gene id: 479434:STHE_RS13775
uniprot id: D1C8M0
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS05870
gene id: 479434:STHE_RS05870
uniprot id: D1C2Y7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

479434:STHE RS15415
gene id: 479434:STHE_RS15415
uniprot id: D1C9I8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS14145
gene id: 479434:STHE_RS14145
uniprot id: D1C8U4
names: Function
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

479434:STHE RS08690
gene id: 479434:STHE_RS08690
uniprot id: D1C4I3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

479434:STHE RS15770
gene id: 479434:STHE_RS15770
uniprot id: D1C9R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479434:STHE RS15120
gene id: 479434:STHE_RS15120
uniprot id: D1C9C9
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS04220
gene id: 479434:STHE_RS04220
uniprot id: D1C215
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

479434:STHE RS05935
gene id: 479434:STHE_RS05935
uniprot id: D1C300
names: Similarity
messages: Belongs to the TPP enzyme family.

479434:STHE RS02860
gene id: 479434:STHE_RS02860
uniprot id: D1C198
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

479434:STHE RS10170
gene id: 479434:STHE_RS10170
uniprot id: D1C5P6
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS02130
gene id: 479434:STHE_RS02130
uniprot id: D1C7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

479434:STHE RS02790
gene id: 479434:STHE_RS02790
uniprot id: D1C183
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

479434:STHE RS15170
gene id: 479434:STHE_RS15170
uniprot id: D1C9D8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS00790
gene id: 479434:STHE_RS00790
uniprot id: D1C662
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS18310
gene id: 479434:STHE_RS18310
uniprot id: D1CA78
names: Similarity
messages: Belongs to the ABC transporter superfamily.

479434:STHE RS01010
gene id: 479434:STHE_RS01010
uniprot id: D1C6A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

479434:STHE RS13410
gene id: 479434:STHE_RS13410
uniprot id: D1C8E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

479434:STHE RS00820
gene id: 479434:STHE_RS00820
uniprot id: D1C668
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS05880
gene id: 479434:STHE_RS05880
uniprot id: D1C2Y9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

479434:STHE RS08660
gene id: 479434:STHE_RS08660
uniprot id: D1C4H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

479434:STHE RS10130
gene id: 479434:STHE_RS10130
uniprot id: D1C5C3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

479434:STHE RS00715
gene id: 479434:STHE_RS00715
uniprot id: D1C647
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

479434:STHE RS07300
gene id: 479434:STHE_RS07300
uniprot id: D1C3R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

479434:STHE RS06840
gene id: 479434:STHE_RS06840
uniprot id: D1C3H2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

479434:STHE RS05940
gene id: 479434:STHE_RS05940
uniprot id: D1C301
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

479434:STHE RS01845
gene id: 479434:STHE_RS01845
uniprot id: D1C7I2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

479434:STHE RS02995
gene id: 479434:STHE_RS02995
uniprot id: D1C1C4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

479434:STHE RS03125
gene id: 479434:STHE_RS03125
uniprot id: D1C1F0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

479434:STHE RS13485
gene id: 479434:STHE_RS13485
uniprot id: D1C8G3
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS02275
gene id: 479434:STHE_RS02275
uniprot id: D1C7R8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

479434:STHE RS07365
gene id: 479434:STHE_RS07365
uniprot id: D1C3S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

479434:STHE RS03175
gene id: 479434:STHE_RS03175
uniprot id: D1C1G1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS14125
gene id: 479434:STHE_RS14125
uniprot id: D1C8U0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

479434:STHE RS01320
gene id: 479434:STHE_RS01320
uniprot id: D1C6U7
names: Subcellular Location Annotation
messages: Cytoplasm

479434:STHE RS11675
gene id: 479434:STHE_RS11675
uniprot id: D1C7A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

479434:STHE RS11195
gene id: 479434:STHE_RS11195
uniprot id: D1C6M3
names: Similarity
messages: Belongs to the CdaR family.

479434:STHE RS01035
gene id: 479434:STHE_RS01035
uniprot id: D1C6B1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

479434:STHE RS08470
gene id: 479434:STHE_RS08470
uniprot id: D1C4E0
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS09320
gene id: 479434:STHE_RS09320
uniprot id: D1C4W0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

479434:STHE RS17660
gene id: 479434:STHE_RS17660
uniprot id: D1C6S2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

479434:STHE RS06505
gene id: 479434:STHE_RS06505
uniprot id: D1C3B0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

479434:STHE RS08020
gene id: 479434:STHE_RS08020
uniprot id: D1C452
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS11085
gene id: 479434:STHE_RS11085
uniprot id: D1C6K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS04035
gene id: 479434:STHE_RS04035
uniprot id: D1C1X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

479434:STHE RS17480
gene id: 479434:STHE_RS17480
uniprot id: D1CAQ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479434:STHE RS14665
gene id: 479434:STHE_RS14665
uniprot id: D1C940
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS10820
gene id: 479434:STHE_RS10820
uniprot id: D1C6F2
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS06325
gene id: 479434:STHE_RS06325
uniprot id: D1C378
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

479434:STHE RS07895
gene id: 479434:STHE_RS07895
uniprot id: D1C431
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

479434:STHE RS09125
gene id: 479434:STHE_RS09125
uniprot id: D1C4S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

479434:STHE RS02735
gene id: 479434:STHE_RS02735
uniprot id: D1C172
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

479434:STHE RS10685
gene id: 479434:STHE_RS10685
uniprot id: D1C5Z8
names: Similarity
messages: Belongs to the peptidase S33 family.

479434:STHE RS09185
gene id: 479434:STHE_RS09185
uniprot id: D1C4T3
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

479434:STHE RS03895
gene id: 479434:STHE_RS03895
uniprot id: D1C1V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

479434:STHE RS12965
gene id: 479434:STHE_RS12965
uniprot id: D1C858
names: Similarity
messages: Belongs to the TPP enzyme family.

479434:STHE RS16505
gene id: 479434:STHE_RS16505
uniprot id: D1CA60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479434:STHE RS05035
gene id: 479434:STHE_RS05035
uniprot id: D1C2H2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS14275
gene id: 479434:STHE_RS14275
uniprot id: D1C8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

479434:STHE RS03550
gene id: 479434:STHE_RS03550
uniprot id: D1C1N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

479434:STHE RS06570
gene id: 479434:STHE_RS06570
uniprot id: D1C3C3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

479434:STHE RS10520
gene id: 479434:STHE_RS10520
uniprot id: D1C5W4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

479434:STHE RS08530
gene id: 479434:STHE_RS08530
uniprot id: D1C4F2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

479434:STHE RS09025
gene id: 479434:STHE_RS09025
uniprot id: D1C4Q1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

479434:STHE RS05285
gene id: 479434:STHE_RS05285
uniprot id: D1C2M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

479434:STHE RS12640
gene id: 479434:STHE_RS12640
uniprot id: D1CAZ3
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

479434:STHE RS08155
gene id: 479434:STHE_RS08155
uniprot id: D1C477
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

479434:STHE RS06930
gene id: 479434:STHE_RS06930
uniprot id: D1C3I9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

479434:STHE RS02085
gene id: 479434:STHE_RS02085
uniprot id: D1C7N0
names: Similarity
messages: Belongs to the arginase family.

479434:STHE RS13505
gene id: 479434:STHE_RS13505
uniprot id: D1C8G7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

479434:STHE RS14480
gene id: 479434:STHE_RS14480
uniprot id: D1C909
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

479434:STHE RS07620
gene id: 479434:STHE_RS07620
uniprot id: D1C3X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS05220
gene id: 479434:STHE_RS05220
uniprot id: D1C2L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

479434:STHE RS09830
gene id: 479434:STHE_RS09830
uniprot id: D1C562
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

479434:STHE RS00005
gene id: 479434:STHE_RS00005
uniprot id: D1C5C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

479434:STHE RS09295
gene id: 479434:STHE_RS09295
uniprot id: D1C4V5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

479434:STHE RS08610
gene id: 479434:STHE_RS08610
uniprot id: D1C4G7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07135
gene id: 479434:STHE_RS07135
uniprot id: D1C3M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

479434:STHE RS14670
gene id: 479434:STHE_RS14670
uniprot id: D1C941
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS11390
gene id: 479434:STHE_RS11390
uniprot id: D1C6R4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

479434:STHE RS07380
gene id: 479434:STHE_RS07380
uniprot id: D1C3S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS05335
gene id: 479434:STHE_RS05335
uniprot id: D1C2N4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

479434:STHE RS09075
gene id: 479434:STHE_RS09075
uniprot id: D1C4R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

479434:STHE RS13935
gene id: 479434:STHE_RS13935
uniprot id: D1C8Q1
names: Similarity
messages: Belongs to the peptidase S9C family.

479434:STHE RS06280
gene id: 479434:STHE_RS06280
uniprot id: D1C369
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

479434:STHE RS05260
gene id: 479434:STHE_RS05260
uniprot id: D1C2L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

479434:STHE RS14280
gene id: 479434:STHE_RS14280
uniprot id: D1C8W9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

479434:STHE RS06235
gene id: 479434:STHE_RS06235
uniprot id: D1C360
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479434:STHE RS11695
gene id: 479434:STHE_RS11695
uniprot id: D1C7A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is likely required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly. In vitro, can also catalyze the release of the q base directly from Q as substrate; however, Q may not be the biologically relevant substrate. Shows a very low activity on queuosine 3',5'-diphosphate, and cannot release q from queuosine 3'-phosphate and from the 5'-nucleotides AMP, UMP, CMP or GMP, indicating specificity for the queuine base.
messages: Monomer.

479434:STHE RS08405
gene id: 479434:STHE_RS08405
uniprot id: D1C4C6
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

479434:STHE RS09315
gene id: 479434:STHE_RS09315
uniprot id: D1C4V9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

479434:STHE RS03985
gene id: 479434:STHE_RS03985
uniprot id: D1C1W7
names: Similarity
messages: Belongs to the TPP enzyme family.

479434:STHE RS16665
gene id: 479434:STHE_RS16665
uniprot id: D1CA93
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS08965
gene id: 479434:STHE_RS08965
uniprot id: D1C4N9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479434:STHE RS00180
gene id: 479434:STHE_RS00180
uniprot id: D1C5G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

479434:STHE RS13060
gene id: 479434:STHE_RS13060
uniprot id: D1C877
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

479434:STHE RS03740
gene id: 479434:STHE_RS03740
uniprot id: D1C1S2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

479434:STHE RS11755
gene id: 479434:STHE_RS11755
uniprot id: D1C7B8
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS07755
gene id: 479434:STHE_RS07755
uniprot id: D1C406
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS04495
gene id: 479434:STHE_RS04495
uniprot id: D1C266
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS14035
gene id: 479434:STHE_RS14035
uniprot id: D1C8S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

479434:STHE RS06875
gene id: 479434:STHE_RS06875
uniprot id: D1C3H9
names: Similarity
messages: Belongs to the DSD1 family.

479434:STHE RS14940
gene id: 479434:STHE_RS14940
uniprot id: D1C993
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

479434:STHE RS00725
gene id: 479434:STHE_RS00725
uniprot id: D1C649
names: Similarity
messages: Belongs to the thioredoxin family.

479434:STHE RS17850
gene id: 479434:STHE_RS17850
uniprot id: D1C2X9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

479434:STHE RS00755
gene id: 479434:STHE_RS00755
uniprot id: D1C655
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS11465
gene id: 479434:STHE_RS11465
uniprot id: D1C759
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

479434:STHE RS16670
gene id: 479434:STHE_RS16670
uniprot id: D1CA94
names: Similarity
messages: Belongs to the peptidase S8 family.

479434:STHE RS01615
gene id: 479434:STHE_RS01615
uniprot id: D1C708
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

479434:STHE RS14935
gene id: 479434:STHE_RS14935
uniprot id: D1C992
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

479434:STHE RS09565
gene id: 479434:STHE_RS09565
uniprot id: D1C509
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS01860
gene id: 479434:STHE_RS01860
uniprot id: D1C7I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

479434:STHE RS05395
gene id: 479434:STHE_RS05395
uniprot id: D1C2P6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479434:STHE RS05315
gene id: 479434:STHE_RS05315
uniprot id: D1C2N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

479434:STHE RS10015
gene id: 479434:STHE_RS10015
uniprot id: D1C5A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

479434:STHE RS06465
gene id: 479434:STHE_RS06465
uniprot id: D1C3A2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS04615
gene id: 479434:STHE_RS04615
uniprot id: D1C290
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

479434:STHE RS08100
gene id: 479434:STHE_RS08100
uniprot id: D1C468
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

479434:STHE RS08655
gene id: 479434:STHE_RS08655
uniprot id: D1C4H6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

479434:STHE RS12250
gene id: 479434:STHE_RS12250
uniprot id: D1C7Z0
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS16510
gene id: 479434:STHE_RS16510
uniprot id: D1CA61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS06085
gene id: 479434:STHE_RS06085
uniprot id: D1C330
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

479434:STHE RS11715
gene id: 479434:STHE_RS11715
uniprot id: D1C7B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

479434:STHE RS07775
gene id: 479434:STHE_RS07775
uniprot id: D1C410
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

479434:STHE RS06490
gene id: 479434:STHE_RS06490
uniprot id: D1C3A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

479434:STHE RS07530
gene id: 479434:STHE_RS07530
uniprot id: D1C3W1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS06070
gene id: 479434:STHE_RS06070
uniprot id: D1C327
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

479434:STHE RS11770
gene id: 479434:STHE_RS11770
uniprot id: D1C7C1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479434:STHE RS16470
gene id: 479434:STHE_RS16470
uniprot id: D1CA53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

479434:STHE RS15410
gene id: 479434:STHE_RS15410
uniprot id: D1C9I7
names: Similarity
messages: Belongs to the histone deacetylase family.

479434:STHE RS04605
gene id: 479434:STHE_RS04605
uniprot id: D1C288
names: Similarity
messages: Belongs to the histone deacetylase family.

479434:STHE RS12540
gene id: 479434:STHE_RS12540
uniprot id: D1CAX3
names: Similarity
messages: Belongs to the universal stress protein A family.

479434:STHE RS04110
gene id: 479434:STHE_RS04110
uniprot id: D1C1Z3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

479434:STHE RS17780
gene id: 479434:STHE_RS17780
uniprot id: D1C1S3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

479434:STHE RS03450
gene id: 479434:STHE_RS03450
uniprot id: D1C1L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

479434:STHE RS13520
gene id: 479434:STHE_RS13520
uniprot id: D1C8H0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

479434:STHE RS15290
gene id: 479434:STHE_RS15290
uniprot id: D1C9G4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

479434:STHE RS09150
gene id: 479434:STHE_RS09150
uniprot id: D1C4S6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

479434:STHE RS03180
gene id: 479434:STHE_RS03180
uniprot id: D1C1G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

479434:STHE RS06495
gene id: 479434:STHE_RS06495
uniprot id: D1C3A8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

479434:STHE RS18055
gene id: 479434:STHE_RS18055
uniprot id: D1C6H5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479434:STHE RS05095
gene id: 479434:STHE_RS05095
uniprot id: D1C2I5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

479434:STHE RS16700
gene id: 479434:STHE_RS16700
uniprot id: D1CAA2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479434:STHE RS09605
gene id: 479434:STHE_RS09605
uniprot id: D1C517
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

479434:STHE RS05470
gene id: 479434:STHE_RS05470
uniprot id: D1C2R1
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

479434:STHE RS01855
gene id: 479434:STHE_RS01855
uniprot id: D1C7I4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

479434:STHE RS05330
gene id: 479434:STHE_RS05330
uniprot id: D1C2N3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

479434:STHE RS16680
gene id: 479434:STHE_RS16680
uniprot id: D1CA96
names: Similarity
messages: Belongs to the FMO family.

479434:STHE RS04365
gene id: 479434:STHE_RS04365
uniprot id: D1C243
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479434:STHE RS06025
gene id: 479434:STHE_RS06025
uniprot id: D1C318
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

479434:STHE RS08940
gene id: 479434:STHE_RS08940
uniprot id: D1C4N4
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS08230
gene id: 479434:STHE_RS08230
uniprot id: D1C491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS09375
gene id: 479434:STHE_RS09375
uniprot id: D1C4X1
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS00925
gene id: 479434:STHE_RS00925
uniprot id: D1C689
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS02875
gene id: 479434:STHE_RS02875
uniprot id: D1C1A1
names: Similarity
messages: Belongs to the MotB family.

479434:STHE RS06750
gene id: 479434:STHE_RS06750
uniprot id: D1C3F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

479434:STHE RS06220
gene id: 479434:STHE_RS06220
uniprot id: D1C357
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

479434:STHE RS09930
gene id: 479434:STHE_RS09930
uniprot id: D1C582
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

479434:STHE RS09545
gene id: 479434:STHE_RS09545
uniprot id: D1C505
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

479434:STHE RS02315
gene id: 479434:STHE_RS02315
uniprot id: D1C7S6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

479434:STHE RS03945
gene id: 479434:STHE_RS03945
uniprot id: D1C1V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

479434:STHE RS03365
gene id: 479434:STHE_RS03365
uniprot id: D1C1J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS13370
gene id: 479434:STHE_RS13370
uniprot id: D1C8E0
names: Similarity
messages: Belongs to the peptidase S16 family.

479434:STHE RS14860
gene id: 479434:STHE_RS14860
uniprot id: D1C978
names: Similarity
messages: Belongs to the YciI family.

479434:STHE RS12200
gene id: 479434:STHE_RS12200
uniprot id: D1C7X9
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

479434:STHE RS04775
gene id: 479434:STHE_RS04775
uniprot id: D1C2C1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS06500
gene id: 479434:STHE_RS06500
uniprot id: D1C3A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

479434:STHE RS01530
gene id: 479434:STHE_RS01530
uniprot id: D1C6Z1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

479434:STHE RS16310
gene id: 479434:STHE_RS16310
uniprot id: D1CA21
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

479434:STHE RS15605
gene id: 479434:STHE_RS15605
uniprot id: D1C9M7
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

479434:STHE RS08550
gene id: 479434:STHE_RS08550
uniprot id: D1C4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

479434:STHE RS06460
gene id: 479434:STHE_RS06460
uniprot id: D1C3A1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS00320
gene id: 479434:STHE_RS00320
uniprot id: D1C5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

479434:STHE RS04070
gene id: 479434:STHE_RS04070
uniprot id: D1C1Y4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS10945
gene id: 479434:STHE_RS10945
uniprot id: D1C6H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

479434:STHE RS09465
gene id: 479434:STHE_RS09465
uniprot id: D1C4Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

479434:STHE RS11455
gene id: 479434:STHE_RS11455
uniprot id: D1C757
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

479434:STHE RS02700
gene id: 479434:STHE_RS02700
uniprot id: D1C165
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

479434:STHE RS02515
gene id: 479434:STHE_RS02515
uniprot id: D1C134
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

479434:STHE RS11105
gene id: 479434:STHE_RS11105
uniprot id: D1C6K7
names: Subcellular Location Annotation
messages: Membrane

479434:STHE RS04120
gene id: 479434:STHE_RS04120
uniprot id: D1C1Z5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

479434:STHE RS03545
gene id: 479434:STHE_RS03545
uniprot id: D1C1N4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

479434:STHE RS02260
gene id: 479434:STHE_RS02260
uniprot id: D1C7R5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS07610
gene id: 479434:STHE_RS07610
uniprot id: D1C3X7
names: Caution
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS04540
gene id: 479434:STHE_RS04540
uniprot id: D1C275
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

479434:STHE RS09440
gene id: 479434:STHE_RS09440
uniprot id: D1C4Y4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

479434:STHE RS04640
gene id: 479434:STHE_RS04640
uniprot id: D1C294
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

479434:STHE RS01285
gene id: 479434:STHE_RS01285
uniprot id: D1C6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479434:STHE RS02010
gene id: 479434:STHE_RS02010
uniprot id: D1C7L5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

479434:STHE RS05340
gene id: 479434:STHE_RS05340
uniprot id: D1C2N5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS04780
gene id: 479434:STHE_RS04780
uniprot id: D1C2C2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

479434:STHE RS12070
gene id: 479434:STHE_RS12070
uniprot id: D1C7H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479434:STHE RS14335
gene id: 479434:STHE_RS14335
uniprot id: D1C8Y0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479434:STHE RS00450
gene id: 479434:STHE_RS00450
uniprot id: D1C5L5
names: Subcellular Location Annotation
messages: Membrane