474394:OCU74 RS05800
gene id: 474394:OCU74_RS05800
uniprot id: A0A1Y6ISP6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

474394:OCU74 RS01635
gene id: 474394:OCU74_RS01635
uniprot id: A0A1Y6IWQ4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

474394:OCU74 RS02275
gene id: 474394:OCU74_RS02275
uniprot id: A0A1Y6IXS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

474394:OCU74 RS14325
gene id: 474394:OCU74_RS14325
uniprot id: A0A1Y6IXB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

474394:OCU74 RS14300
gene id: 474394:OCU74_RS14300
uniprot id: A0A1Y6IXD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

474394:OCU74 RS14365
gene id: 474394:OCU74_RS14365
uniprot id: A0A1Y6IXC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

474394:OCU74 RS14400
gene id: 474394:OCU74_RS14400
uniprot id: A0A1Y6IX86
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

474394:OCU74 RS14415
gene id: 474394:OCU74_RS14415
uniprot id: A0A1Y6IXA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

474394:OCU74 RS03565
gene id: 474394:OCU74_RS03565
uniprot id: A0A1Y6IRF4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

474394:OCU74 RS09890
gene id: 474394:OCU74_RS09890
uniprot id: A0A1Y6IPI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

474394:OCU74 RS05775
gene id: 474394:OCU74_RS05775
uniprot id: A0A1Y6IX81
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

474394:OCU74 RS02190
gene id: 474394:OCU74_RS02190
uniprot id: A0A1Y6IXQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

474394:OCU74 RS01875
gene id: 474394:OCU74_RS01875
uniprot id: A0A1Y6IUV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

474394:OCU74 RS01835
gene id: 474394:OCU74_RS01835
uniprot id: A0A1Y6IUW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

474394:OCU74 RS01840
gene id: 474394:OCU74_RS01840
uniprot id: A0A1Y6IUS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

474394:OCU74 RS14395
gene id: 474394:OCU74_RS14395
uniprot id: A0A1Y6IZM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

474394:OCU74 RS14425
gene id: 474394:OCU74_RS14425
uniprot id: A0A1Y6IX98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

474394:OCU74 RS21210
gene id: 474394:OCU74_RS21210
uniprot id: A0A1Y6IY97
names: Subcellular Location Annotation
messages: Cytoplasm

474394:OCU74 RS14765
gene id: 474394:OCU74_RS14765
uniprot id: A0A1Y6IZ07
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

474394:OCU74 RS19325
gene id: 474394:OCU74_RS19325
uniprot id: A0A1Y6IWK2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

474394:OCU74 RS14370
gene id: 474394:OCU74_RS14370
uniprot id: A0A1Y6IX84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

474394:OCU74 RS14380
gene id: 474394:OCU74_RS14380
uniprot id: A0A1Y6J1T6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

474394:OCU74 RS16305
gene id: 474394:OCU74_RS16305
uniprot id: A0A1Y6IYG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

474394:OCU74 RS14305
gene id: 474394:OCU74_RS14305
uniprot id: A0A1Y6IXB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

474394:OCU74 RS01065
gene id: 474394:OCU74_RS01065
uniprot id: A0A1Y6IZW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

474394:OCU74 RS03220
gene id: 474394:OCU74_RS03220
uniprot id: A0A1Y6IUI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

474394:OCU74 RS12895
gene id: 474394:OCU74_RS12895
uniprot id: A0A1Y6IUI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

474394:OCU74 RS01060
gene id: 474394:OCU74_RS01060
uniprot id: A0A1Y6IV79
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

474394:OCU74 RS01775
gene id: 474394:OCU74_RS01775
uniprot id: A0A1Y6IUX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

474394:OCU74 RS06730
gene id: 474394:OCU74_RS06730
uniprot id: A0A1Y6IMQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

474394:OCU74 RS14785
gene id: 474394:OCU74_RS14785
uniprot id: A0A1Y6J3J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

474394:OCU74 RS14290
gene id: 474394:OCU74_RS14290
uniprot id: A0A1Y6IZP7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

474394:OCU74 RS19330
gene id: 474394:OCU74_RS19330
uniprot id: A0A1Y6IYY2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.