469383:CWOE RS18230
gene id: 469383:CWOE_RS18230
uniprot id: D3F195
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS07535
gene id: 469383:CWOE_RS07535
uniprot id: D3EZV9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS18920
gene id: 469383:CWOE_RS18920
uniprot id: D3F2C9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

469383:CWOE RS17485
gene id: 469383:CWOE_RS17485
uniprot id: D3EZF3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS03320
gene id: 469383:CWOE_RS03320
uniprot id: D3F9D3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS17740
gene id: 469383:CWOE_RS17740
uniprot id: D3F0A6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS21460
gene id: 469383:CWOE_RS21460
uniprot id: D3F6P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS07685
gene id: 469383:CWOE_RS07685
uniprot id: D3EZZ0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

469383:CWOE RS20775
gene id: 469383:CWOE_RS20775
uniprot id: D3F4U9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

469383:CWOE RS27320
gene id: 469383:CWOE_RS27320
uniprot id: D3EZK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS21845
gene id: 469383:CWOE_RS21845
uniprot id: D3F6X0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

469383:CWOE RS29510
gene id: 469383:CWOE_RS29510
uniprot id: D3F2Z7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

469383:CWOE RS16490
gene id: 469383:CWOE_RS16490
uniprot id: D3FF04
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS05790
gene id: 469383:CWOE_RS05790
uniprot id: D3FDL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

469383:CWOE RS01760
gene id: 469383:CWOE_RS01760
uniprot id: D3F715
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

469383:CWOE RS08600
gene id: 469383:CWOE_RS08600
uniprot id: D3F174
names: Subcellular Location Annotation
messages: Cell membrane

469383:CWOE RS30765
gene id: 469383:CWOE_RS30765
uniprot id: D3FD39
names: Similarity
messages: Belongs to the ice-binding protein family.

469383:CWOE RS18560
gene id: 469383:CWOE_RS18560
uniprot id: D3F1G2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

469383:CWOE RS01885
gene id: 469383:CWOE_RS01885
uniprot id: D3F740
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS09030
gene id: 469383:CWOE_RS09030
uniprot id: D3F261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

469383:CWOE RS02730
gene id: 469383:CWOE_RS02730
uniprot id: D3F8B0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS00260
gene id: 469383:CWOE_RS00260
uniprot id: D3F405
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

469383:CWOE RS00785
gene id: 469383:CWOE_RS00785
uniprot id: D3F513
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00190
gene id: 469383:CWOE_RS00190
uniprot id: D3F3Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

469383:CWOE RS15520
gene id: 469383:CWOE_RS15520
uniprot id: D3FD16
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS12370
gene id: 469383:CWOE_RS12370
uniprot id: D3F7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

469383:CWOE RS15485
gene id: 469383:CWOE_RS15485
uniprot id: D3FD10
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

469383:CWOE RS01860
gene id: 469383:CWOE_RS01860
uniprot id: D3F735
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

469383:CWOE RS00395
gene id: 469383:CWOE_RS00395
uniprot id: D3F430
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

469383:CWOE RS19055
gene id: 469383:CWOE_RS19055
uniprot id: D3F2F5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

469383:CWOE RS23340
gene id: 469383:CWOE_RS23340
uniprot id: D3F965
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

469383:CWOE RS12420
gene id: 469383:CWOE_RS12420
uniprot id: D3F7Q1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS21475
gene id: 469383:CWOE_RS21475
uniprot id: D3F6P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

469383:CWOE RS05805
gene id: 469383:CWOE_RS05805
uniprot id: D3FDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

469383:CWOE RS18930
gene id: 469383:CWOE_RS18930
uniprot id: D3F2D1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS26250
gene id: 469383:CWOE_RS26250
uniprot id: D3FEE4
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

469383:CWOE RS28480
gene id: 469383:CWOE_RS28480
uniprot id: D3F1P3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS20820
gene id: 469383:CWOE_RS20820
uniprot id: D3F5L6
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

469383:CWOE RS13300
gene id: 469383:CWOE_RS13300
uniprot id: D3F9M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

469383:CWOE RS25425
gene id: 469383:CWOE_RS25425
uniprot id: D3FD85
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS29705
gene id: 469383:CWOE_RS29705
uniprot id: D3F3U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

469383:CWOE RS29195
gene id: 469383:CWOE_RS29195
uniprot id: D3F2T4
names: Similarity
messages: Belongs to the citrate synthase family.

469383:CWOE RS05865
gene id: 469383:CWOE_RS05865
uniprot id: D3FDN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

469383:CWOE RS08075
gene id: 469383:CWOE_RS08075
uniprot id: D3F0X0
names: Similarity
messages: Belongs to the glutamine synthetase family.

469383:CWOE RS26150
gene id: 469383:CWOE_RS26150
uniprot id: D3FEC5
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

469383:CWOE RS00665
gene id: 469383:CWOE_RS00665
uniprot id: D3F4Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS00400
gene id: 469383:CWOE_RS00400
uniprot id: D3F431
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

469383:CWOE RS19935
gene id: 469383:CWOE_RS19935
uniprot id: D3F3M8
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

469383:CWOE RS20440
gene id: 469383:CWOE_RS20440
uniprot id: D3F4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS17575
gene id: 469383:CWOE_RS17575
uniprot id: D3F076
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

469383:CWOE RS23355
gene id: 469383:CWOE_RS23355
uniprot id: D3F9W8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

469383:CWOE RS09270
gene id: 469383:CWOE_RS09270
uniprot id: D3F2B0
names: Function
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).

469383:CWOE RS12475
gene id: 469383:CWOE_RS12475
uniprot id: D3F7R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS20560
gene id: 469383:CWOE_RS20560
uniprot id: D3F4Q6
names: Similarity
messages: Belongs to the TPP enzyme family.

469383:CWOE RS21290
gene id: 469383:CWOE_RS21290
uniprot id: D3F5V7
names: Similarity
messages: Belongs to the glutamine synthetase family.

469383:CWOE RS03940
gene id: 469383:CWOE_RS03940
uniprot id: D3FAF4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

469383:CWOE RS28360
gene id: 469383:CWOE_RS28360
uniprot id: D3F1L9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

469383:CWOE RS32380
gene id: 469383:CWOE_RS32380
uniprot id: D3F500
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

469383:CWOE RS05455
gene id: 469383:CWOE_RS05455
uniprot id: D3FCP9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS33650
gene id: 469383:CWOE_RS33650
uniprot id: D3FB65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS16330
gene id: 469383:CWOE_RS16330
uniprot id: D3FEX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

469383:CWOE RS27710
gene id: 469383:CWOE_RS27710
uniprot id: D3EZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

469383:CWOE RS25450
gene id: 469383:CWOE_RS25450
uniprot id: D3FD90
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS10420
gene id: 469383:CWOE_RS10420
uniprot id: D3F4E3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS18430
gene id: 469383:CWOE_RS18430
uniprot id: D3F1D6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

469383:CWOE RS06015
gene id: 469383:CWOE_RS06015
uniprot id: D3FDQ6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

469383:CWOE RS23825
gene id: 469383:CWOE_RS23825
uniprot id: D3FA60
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

469383:CWOE RS24505
gene id: 469383:CWOE_RS24505
uniprot id: D3FBA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS13380
gene id: 469383:CWOE_RS13380
uniprot id: D3F9P1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS06655
gene id: 469383:CWOE_RS06655
uniprot id: D3FET3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

469383:CWOE RS08550
gene id: 469383:CWOE_RS08550
uniprot id: D3F164
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS13590
gene id: 469383:CWOE_RS13590
uniprot id: D3F9T2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

469383:CWOE RS22970
gene id: 469383:CWOE_RS22970
uniprot id: D3F8Z1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS05695
gene id: 469383:CWOE_RS05695
uniprot id: D3FDJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

469383:CWOE RS26580
gene id: 469383:CWOE_RS26580
uniprot id: D3FFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

469383:CWOE RS23150
gene id: 469383:CWOE_RS23150
uniprot id: D3F927
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

469383:CWOE RS12390
gene id: 469383:CWOE_RS12390
uniprot id: D3F7P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

469383:CWOE RS18805
gene id: 469383:CWOE_RS18805
uniprot id: D3F1L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

469383:CWOE RS29130
gene id: 469383:CWOE_RS29130
uniprot id: D3F2S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS28715
gene id: 469383:CWOE_RS28715
uniprot id: D3F1T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS03280
gene id: 469383:CWOE_RS03280
uniprot id: D3F9C5
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS14160
gene id: 469383:CWOE_RS14160
uniprot id: D3FAU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

469383:CWOE RS18700
gene id: 469383:CWOE_RS18700
uniprot id: D3F1J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469383:CWOE RS04645
gene id: 469383:CWOE_RS04645
uniprot id: D3FBJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS06685
gene id: 469383:CWOE_RS06685
uniprot id: D3FET9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

469383:CWOE RS04995
gene id: 469383:CWOE_RS04995
uniprot id: D3FCF9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

469383:CWOE RS04760
gene id: 469383:CWOE_RS04760
uniprot id: D3FBL6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS04080
gene id: 469383:CWOE_RS04080
uniprot id: D3FAI2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

469383:CWOE RS29345
gene id: 469383:CWOE_RS29345
uniprot id: D3F2W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

469383:CWOE RS12695
gene id: 469383:CWOE_RS12695
uniprot id: D3F8K4
names: Similarity
messages: Belongs to the peptidase A31 family.

469383:CWOE RS19610
gene id: 469383:CWOE_RS19610
uniprot id: D3F3G5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

469383:CWOE RS04025
gene id: 469383:CWOE_RS04025
uniprot id: D3FAH1
names: Similarity
messages: Belongs to the GARS family.

469383:CWOE RS12720
gene id: 469383:CWOE_RS12720
uniprot id: D3F8K9
names: Similarity
messages: Belongs to the AHA1 family.

469383:CWOE RS06755
gene id: 469383:CWOE_RS06755
uniprot id: D3FEV3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

469383:CWOE RS25860
gene id: 469383:CWOE_RS25860
uniprot id: D3FE72
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS03950
gene id: 469383:CWOE_RS03950
uniprot id: D3FAF6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS29760
gene id: 469383:CWOE_RS29760
uniprot id: D3F3V1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS20740
gene id: 469383:CWOE_RS20740
uniprot id: D3F4U2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

469383:CWOE RS23745
gene id: 469383:CWOE_RS23745
uniprot id: D3FA44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

469383:CWOE RS11665
gene id: 469383:CWOE_RS11665
uniprot id: D3F6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

469383:CWOE RS23390
gene id: 469383:CWOE_RS23390
uniprot id: D3F9X5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS20790
gene id: 469383:CWOE_RS20790
uniprot id: D3F5L0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS06570
gene id: 469383:CWOE_RS06570
uniprot id: D3FER6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS15260
gene id: 469383:CWOE_RS15260
uniprot id: D3FCW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

469383:CWOE RS07750
gene id: 469383:CWOE_RS07750
uniprot id: D3F003
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS19140
gene id: 469383:CWOE_RS19140
uniprot id: D3F2H2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

469383:CWOE RS14410
gene id: 469383:CWOE_RS14410
uniprot id: D3FBP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

469383:CWOE RS05145
gene id: 469383:CWOE_RS05145
uniprot id: D3FCI8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

469383:CWOE RS10225
gene id: 469383:CWOE_RS10225
uniprot id: D3F4A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS05825
gene id: 469383:CWOE_RS05825
uniprot id: D3FDM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

469383:CWOE RS01535
gene id: 469383:CWOE_RS01535
uniprot id: D3F668
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469383:CWOE RS29785
gene id: 469383:CWOE_RS29785
uniprot id: D3F3V6
names: Similarity
messages: Belongs to the Ahb/Nir family.

469383:CWOE RS13160
gene id: 469383:CWOE_RS13160
uniprot id: D3F9J6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS07710
gene id: 469383:CWOE_RS07710
uniprot id: D3EZZ5
names: Similarity
messages: Belongs to the CdaR family.

469383:CWOE RS13560
gene id: 469383:CWOE_RS13560
uniprot id: D3F9S6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS30750
gene id: 469383:CWOE_RS30750
uniprot id: D3FCY5
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

469383:CWOE RS08465
gene id: 469383:CWOE_RS08465
uniprot id: D3F147
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS19865
gene id: 469383:CWOE_RS19865
uniprot id: D3F3L5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

469383:CWOE RS19210
gene id: 469383:CWOE_RS19210
uniprot id: D3F2I6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS27325
gene id: 469383:CWOE_RS27325
uniprot id: D3EZK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS13200
gene id: 469383:CWOE_RS13200
uniprot id: D3F9K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

469383:CWOE RS31110
gene id: 469383:CWOE_RS31110
uniprot id: D3F3M5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

469383:CWOE RS23790
gene id: 469383:CWOE_RS23790
uniprot id: D3FA53
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS21945
gene id: 469383:CWOE_RS21945
uniprot id: D3F6Z0
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

469383:CWOE RS23315
gene id: 469383:CWOE_RS23315
uniprot id: D3F960
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

469383:CWOE RS26540
gene id: 469383:CWOE_RS26540
uniprot id: D3FFA1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

469383:CWOE RS06775
gene id: 469383:CWOE_RS06775
uniprot id: D3FEV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

469383:CWOE RS04170
gene id: 469383:CWOE_RS04170
uniprot id: D3FAJ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS23870
gene id: 469383:CWOE_RS23870
uniprot id: D3FA69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

469383:CWOE RS15525
gene id: 469383:CWOE_RS15525
uniprot id: D3FD17
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

469383:CWOE RS27885
gene id: 469383:CWOE_RS27885
uniprot id: D3F0M3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS00730
gene id: 469383:CWOE_RS00730
uniprot id: D3F502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

469383:CWOE RS23190
gene id: 469383:CWOE_RS23190
uniprot id: D3F935
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

469383:CWOE RS03735
gene id: 469383:CWOE_RS03735
uniprot id: D3FAB2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

469383:CWOE RS17905
gene id: 469383:CWOE_RS17905
uniprot id: D3F0D8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

469383:CWOE RS20875
gene id: 469383:CWOE_RS20875
uniprot id: D3F5M7
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

469383:CWOE RS02900
gene id: 469383:CWOE_RS02900
uniprot id: D3F8E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS28130
gene id: 469383:CWOE_RS28130
uniprot id: D3F0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS01460
gene id: 469383:CWOE_RS01460
uniprot id: D3F653
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

469383:CWOE RS12665
gene id: 469383:CWOE_RS12665
uniprot id: D3F8J8
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

469383:CWOE RS05800
gene id: 469383:CWOE_RS05800
uniprot id: D3FDL7
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS14225
gene id: 469383:CWOE_RS14225
uniprot id: D3FAV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469383:CWOE RS06320
gene id: 469383:CWOE_RS06320
uniprot id: D3FEL5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

469383:CWOE RS19825
gene id: 469383:CWOE_RS19825
uniprot id: D3F3K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS31605
gene id: 469383:CWOE_RS31605
uniprot id: D3EZJ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS20720
gene id: 469383:CWOE_RS20720
uniprot id: D3F4T8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

469383:CWOE RS02895
gene id: 469383:CWOE_RS02895
uniprot id: D3F8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS26385
gene id: 469383:CWOE_RS26385
uniprot id: D3FEH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

469383:CWOE RS16135
gene id: 469383:CWOE_RS16135
uniprot id: D3FE34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

469383:CWOE RS04345
gene id: 469383:CWOE_RS04345
uniprot id: D3FBD3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS12835
gene id: 469383:CWOE_RS12835
uniprot id: D3F8N1
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

469383:CWOE RS17505
gene id: 469383:CWOE_RS17505
uniprot id: D3EZF7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

469383:CWOE RS24995
gene id: 469383:CWOE_RS24995
uniprot id: D3FC97
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS13950
gene id: 469383:CWOE_RS13950
uniprot id: D3FAQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

469383:CWOE RS20675
gene id: 469383:CWOE_RS20675
uniprot id: D3F4S9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS18090
gene id: 469383:CWOE_RS18090
uniprot id: D3F0H4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

469383:CWOE RS30450
gene id: 469383:CWOE_RS30450
uniprot id: D3F184
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

469383:CWOE RS23740
gene id: 469383:CWOE_RS23740
uniprot id: D3FA43
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469383:CWOE RS14190
gene id: 469383:CWOE_RS14190
uniprot id: D3FAV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

469383:CWOE RS14275
gene id: 469383:CWOE_RS14275
uniprot id: D3FAW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS02640
gene id: 469383:CWOE_RS02640
uniprot id: D3F892
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS22550
gene id: 469383:CWOE_RS22550
uniprot id: D3F811
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

469383:CWOE RS16925
gene id: 469383:CWOE_RS16925
uniprot id: D3EZ42
names: Similarity
messages: Belongs to the DEAD box helicase family.

469383:CWOE RS06925
gene id: 469383:CWOE_RS06925
uniprot id: D3EYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

469383:CWOE RS13495
gene id: 469383:CWOE_RS13495
uniprot id: D3F9R3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469383:CWOE RS01540
gene id: 469383:CWOE_RS01540
uniprot id: D3F669
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS32420
gene id: 469383:CWOE_RS32420
uniprot id: D3F860
names: Similarity
messages: Belongs to the CdaR family.

469383:CWOE RS04935
gene id: 469383:CWOE_RS04935
uniprot id: D3FCE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS17250
gene id: 469383:CWOE_RS17250
uniprot id: D3EZA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

469383:CWOE RS29410
gene id: 469383:CWOE_RS29410
uniprot id: D3F2X6
names: Similarity
messages: Belongs to the TPP enzyme family.

469383:CWOE RS22900
gene id: 469383:CWOE_RS22900
uniprot id: D3F8X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS03325
gene id: 469383:CWOE_RS03325
uniprot id: D3F9D4
names: Similarity
messages: Belongs to the DSD1 family.

469383:CWOE RS13800
gene id: 469383:CWOE_RS13800
uniprot id: D3FAM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS13275
gene id: 469383:CWOE_RS13275
uniprot id: D3F9M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

469383:CWOE RS24800
gene id: 469383:CWOE_RS24800
uniprot id: D3FC57
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469383:CWOE RS23625
gene id: 469383:CWOE_RS23625
uniprot id: D3FA21
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

469383:CWOE RS10875
gene id: 469383:CWOE_RS10875
uniprot id: D3F5D9
names: Similarity
messages: Belongs to the peptidase M29 family.

469383:CWOE RS15050
gene id: 469383:CWOE_RS15050
uniprot id: D3FCS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS21530
gene id: 469383:CWOE_RS21530
uniprot id: D3F6Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

469383:CWOE RS08405
gene id: 469383:CWOE_RS08405
uniprot id: D3F136
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

469383:CWOE RS04925
gene id: 469383:CWOE_RS04925
uniprot id: D3FCE5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS12580
gene id: 469383:CWOE_RS12580
uniprot id: D3F8I1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS09065
gene id: 469383:CWOE_RS09065
uniprot id: D3F268
names: Similarity
messages: Belongs to the glutamate synthase family.

469383:CWOE RS23805
gene id: 469383:CWOE_RS23805
uniprot id: D3FA56
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

469383:CWOE RS05760
gene id: 469383:CWOE_RS05760
uniprot id: D3FDK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

469383:CWOE RS25835
gene id: 469383:CWOE_RS25835
uniprot id: D3FE67
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS17645
gene id: 469383:CWOE_RS17645
uniprot id: D3F090
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

469383:CWOE RS31450
gene id: 469383:CWOE_RS31450
uniprot id: D3FD52
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS02055
gene id: 469383:CWOE_RS02055
uniprot id: D3F775
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS30875
gene id: 469383:CWOE_RS30875
uniprot id: D3EZ59
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469383:CWOE RS11155
gene id: 469383:CWOE_RS11155
uniprot id: D3F5J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS03980
gene id: 469383:CWOE_RS03980
uniprot id: D3FAG2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

469383:CWOE RS27615
gene id: 469383:CWOE_RS27615
uniprot id: D3EZR4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS06780
gene id: 469383:CWOE_RS06780
uniprot id: D3FEV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

469383:CWOE RS27920
gene id: 469383:CWOE_RS27920
uniprot id: D3F0N0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS04570
gene id: 469383:CWOE_RS04570
uniprot id: D3FBH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS22200
gene id: 469383:CWOE_RS22200
uniprot id: D3F7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS01085
gene id: 469383:CWOE_RS01085
uniprot id: D3F575
names: Similarity
messages: Belongs to the AHA1 family.

469383:CWOE RS19735
gene id: 469383:CWOE_RS19735
uniprot id: D3F3J0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS26955
gene id: 469383:CWOE_RS26955
uniprot id: D3FFI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

469383:CWOE RS27845
gene id: 469383:CWOE_RS27845
uniprot id: D3F0L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

469383:CWOE RS25745
gene id: 469383:CWOE_RS25745
uniprot id: D3FDE9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

469383:CWOE RS27925
gene id: 469383:CWOE_RS27925
uniprot id: D3F0N1
names: Similarity
messages: Belongs to the peptidase S11 family.

469383:CWOE RS28175
gene id: 469383:CWOE_RS28175
uniprot id: D3F0T0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

469383:CWOE RS09995
gene id: 469383:CWOE_RS09995
uniprot id: D3F460
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

469383:CWOE RS19110
gene id: 469383:CWOE_RS19110
uniprot id: D3F2G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

469383:CWOE RS16455
gene id: 469383:CWOE_RS16455
uniprot id: D3FEZ7
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

469383:CWOE RS16100
gene id: 469383:CWOE_RS16100
uniprot id: D3FE27
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

469383:CWOE RS21550
gene id: 469383:CWOE_RS21550
uniprot id: D3F6R1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS14655
gene id: 469383:CWOE_RS14655
uniprot id: D3FBU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS30845
gene id: 469383:CWOE_RS30845
uniprot id: D3FF51
names: Similarity
messages: Belongs to the peptidase S9C family.

469383:CWOE RS02275
gene id: 469383:CWOE_RS02275
uniprot id: D3F7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS06635
gene id: 469383:CWOE_RS06635
uniprot id: D3FET0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

469383:CWOE RS03715
gene id: 469383:CWOE_RS03715
uniprot id: D3FAA8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

469383:CWOE RS17750
gene id: 469383:CWOE_RS17750
uniprot id: D3F0A8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

469383:CWOE RS17565
gene id: 469383:CWOE_RS17565
uniprot id: D3F074
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

469383:CWOE RS27800
gene id: 469383:CWOE_RS27800
uniprot id: D3F0K6
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

469383:CWOE RS34150
gene id: 469383:CWOE_RS34150
uniprot id: D3EZF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

469383:CWOE RS09505
gene id: 469383:CWOE_RS09505
uniprot id: D3F354
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

469383:CWOE RS30740
gene id: 469383:CWOE_RS30740
uniprot id: D3FBZ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS08590
gene id: 469383:CWOE_RS08590
uniprot id: D3F172
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

469383:CWOE RS25680
gene id: 469383:CWOE_RS25680
uniprot id: D3FDD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS12415
gene id: 469383:CWOE_RS12415
uniprot id: D3F7Q0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS08255
gene id: 469383:CWOE_RS08255
uniprot id: D3F106
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Membrane

469383:CWOE RS29790
gene id: 469383:CWOE_RS29790
uniprot id: D3F3V7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

469383:CWOE RS14580
gene id: 469383:CWOE_RS14580
uniprot id: D3FBS6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS17315
gene id: 469383:CWOE_RS17315
uniprot id: D3EZB9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS07790
gene id: 469383:CWOE_RS07790
uniprot id: D3F011
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

469383:CWOE RS03650
gene id: 469383:CWOE_RS03650
uniprot id: D3FA95
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS01920
gene id: 469383:CWOE_RS01920
uniprot id: D3F747
names: Similarity
messages: Belongs to the YciI family.

469383:CWOE RS23100
gene id: 469383:CWOE_RS23100
uniprot id: D3F917
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

469383:CWOE RS27595
gene id: 469383:CWOE_RS27595
uniprot id: D3EZR0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

469383:CWOE RS15490
gene id: 469383:CWOE_RS15490
uniprot id: D3FD11
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

469383:CWOE RS22555
gene id: 469383:CWOE_RS22555
uniprot id: D3F812
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

469383:CWOE RS29110
gene id: 469383:CWOE_RS29110
uniprot id: D3F2R7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

469383:CWOE RS13195
gene id: 469383:CWOE_RS13195
uniprot id: D3F9K4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

469383:CWOE RS01635
gene id: 469383:CWOE_RS01635
uniprot id: D3F688
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

469383:CWOE RS31685
gene id: 469383:CWOE_RS31685
uniprot id: D3F0V5
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS06705
gene id: 469383:CWOE_RS06705
uniprot id: D3FEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

469383:CWOE RS16430
gene id: 469383:CWOE_RS16430
uniprot id: D3FEZ2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS26310
gene id: 469383:CWOE_RS26310
uniprot id: D3FEF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

469383:CWOE RS19785
gene id: 469383:CWOE_RS19785
uniprot id: D3F3K0
names: Subcellular Location Annotation
messages: Cytoplasm

469383:CWOE RS15995
gene id: 469383:CWOE_RS15995
uniprot id: D3FE06
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

469383:CWOE RS21400
gene id: 469383:CWOE_RS21400
uniprot id: D3F5X9
names: Similarity
messages: Belongs to the universal stress protein A family.

469383:CWOE RS15375
gene id: 469383:CWOE_RS15375
uniprot id: D3FCY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS31175
gene id: 469383:CWOE_RS31175
uniprot id: D3F5T8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469383:CWOE RS01380
gene id: 469383:CWOE_RS01380
uniprot id: D3F637
names: Similarity
messages: Belongs to the peptidase S8 family.

469383:CWOE RS08805
gene id: 469383:CWOE_RS08805
uniprot id: D3F214
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS31040
gene id: 469383:CWOE_RS31040
uniprot id: D3F1J5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

469383:CWOE RS21095
gene id: 469383:CWOE_RS21095
uniprot id: D3F5S0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

469383:CWOE RS04365
gene id: 469383:CWOE_RS04365
uniprot id: D3FBD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

469383:CWOE RS28085
gene id: 469383:CWOE_RS28085
uniprot id: D3F0R3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS22750
gene id: 469383:CWOE_RS22750
uniprot id: D3F8U8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

469383:CWOE RS03905
gene id: 469383:CWOE_RS03905
uniprot id: D3FAE6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

469383:CWOE RS28945
gene id: 469383:CWOE_RS28945
uniprot id: D3F1Y4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

469383:CWOE RS05645
gene id: 469383:CWOE_RS05645
uniprot id: D3FDI6
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

469383:CWOE RS16075
gene id: 469383:CWOE_RS16075
uniprot id: D3FE22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

469383:CWOE RS33775
gene id: 469383:CWOE_RS33775
uniprot id: D3FAH2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

469383:CWOE RS12500
gene id: 469383:CWOE_RS12500
uniprot id: D3F8G5
names: Similarity
messages: Belongs to the YciI family.

469383:CWOE RS16815
gene id: 469383:CWOE_RS16815
uniprot id: D3FF69
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

469383:CWOE RS10685
gene id: 469383:CWOE_RS10685
uniprot id: D3F5A1
names: Function
names: Similarity
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

469383:CWOE RS16180
gene id: 469383:CWOE_RS16180
uniprot id: D3FE43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

469383:CWOE RS24410
gene id: 469383:CWOE_RS24410
uniprot id: D3FB82
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS18675
gene id: 469383:CWOE_RS18675
uniprot id: D3F1I5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

469383:CWOE RS31230
gene id: 469383:CWOE_RS31230
uniprot id: D3F6Z4
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS11205
gene id: 469383:CWOE_RS11205
uniprot id: D3F5K5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

469383:CWOE RS07305
gene id: 469383:CWOE_RS07305
uniprot id: D3EZ14
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS23395
gene id: 469383:CWOE_RS23395
uniprot id: D3F9X6
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

469383:CWOE RS23280
gene id: 469383:CWOE_RS23280
uniprot id: D3F953
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

469383:CWOE RS00905
gene id: 469383:CWOE_RS00905
uniprot id: D3F539
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

469383:CWOE RS19720
gene id: 469383:CWOE_RS19720
uniprot id: D3F3I7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

469383:CWOE RS27645
gene id: 469383:CWOE_RS27645
uniprot id: D3EZS0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS23195
gene id: 469383:CWOE_RS23195
uniprot id: D3F936
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

469383:CWOE RS20530
gene id: 469383:CWOE_RS20530
uniprot id: D3F4Q0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS30755
gene id: 469383:CWOE_RS30755
uniprot id: D3FD13
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

469383:CWOE RS14200
gene id: 469383:CWOE_RS14200
uniprot id: D3FAV2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

469383:CWOE RS17220
gene id: 469383:CWOE_RS17220
uniprot id: D3EZA0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

469383:CWOE RS09430
gene id: 469383:CWOE_RS09430
uniprot id: D3F338
names: Subcellular Location Annotation
messages: Cytoplasm

469383:CWOE RS13280
gene id: 469383:CWOE_RS13280
uniprot id: D3F9M2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

469383:CWOE RS16420
gene id: 469383:CWOE_RS16420
uniprot id: D3FEZ0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS01340
gene id: 469383:CWOE_RS01340
uniprot id: D3F629
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

469383:CWOE RS07565
gene id: 469383:CWOE_RS07565
uniprot id: D3EZW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: In the N-terminal section; belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

469383:CWOE RS27865
gene id: 469383:CWOE_RS27865
uniprot id: D3F0L9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS15765
gene id: 469383:CWOE_RS15765
uniprot id: D3FDW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

469383:CWOE RS28930
gene id: 469383:CWOE_RS28930
uniprot id: D3F1Y1
names: Similarity
messages: Belongs to the thioredoxin family.

469383:CWOE RS16275
gene id: 469383:CWOE_RS16275
uniprot id: D3FE61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

469383:CWOE RS14465
gene id: 469383:CWOE_RS14465
uniprot id: D3FBQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

469383:CWOE RS28285
gene id: 469383:CWOE_RS28285
uniprot id: D3F0V1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS02180
gene id: 469383:CWOE_RS02180
uniprot id: D3F7A1
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

469383:CWOE RS03315
gene id: 469383:CWOE_RS03315
uniprot id: D3F9D2
names: Similarity
messages: Belongs to the RutC family.

469383:CWOE RS29355
gene id: 469383:CWOE_RS29355
uniprot id: D3F2W5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

469383:CWOE RS21675
gene id: 469383:CWOE_RS21675
uniprot id: D3F6T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

469383:CWOE RS02330
gene id: 469383:CWOE_RS02330
uniprot id: D3F7D1
names: Similarity
messages: Belongs to the CsoR family.

469383:CWOE RS17780
gene id: 469383:CWOE_RS17780
uniprot id: D3F0B4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS01655
gene id: 469383:CWOE_RS01655
uniprot id: D3F692
names: Similarity
messages: Belongs to the AHA1 family.

469383:CWOE RS08335
gene id: 469383:CWOE_RS08335
uniprot id: D3F122
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

469383:CWOE RS01435
gene id: 469383:CWOE_RS01435
uniprot id: D3F648
names: Similarity
messages: Belongs to the peptidase S33 family.

469383:CWOE RS20160
gene id: 469383:CWOE_RS20160
uniprot id: D3F4I1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

469383:CWOE RS29100
gene id: 469383:CWOE_RS29100
uniprot id: D3F2R5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

469383:CWOE RS01690
gene id: 469383:CWOE_RS01690
uniprot id: D3F699
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS01030
gene id: 469383:CWOE_RS01030
uniprot id: D3F564
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

469383:CWOE RS05795
gene id: 469383:CWOE_RS05795
uniprot id: D3FDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

469383:CWOE RS28425
gene id: 469383:CWOE_RS28425
uniprot id: D3F1N2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS29670
gene id: 469383:CWOE_RS29670
uniprot id: D3F3T4
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

469383:CWOE RS15440
gene id: 469383:CWOE_RS15440
uniprot id: D3FD01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469383:CWOE RS28790
gene id: 469383:CWOE_RS28790
uniprot id: D3F1V3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS17320
gene id: 469383:CWOE_RS17320
uniprot id: D3EZC0
names: Similarity
messages: Belongs to the group II decarboxylase family.

469383:CWOE RS11780
gene id: 469383:CWOE_RS11780
uniprot id: D3F6M1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS22745
gene id: 469383:CWOE_RS22745
uniprot id: D3F8U7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

469383:CWOE RS08420
gene id: 469383:CWOE_RS08420
uniprot id: D3F139
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

469383:CWOE RS12120
gene id: 469383:CWOE_RS12120
uniprot id: D3F7J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS06700
gene id: 469383:CWOE_RS06700
uniprot id: D3FEU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

469383:CWOE RS14795
gene id: 469383:CWOE_RS14795
uniprot id: D3FBX0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

469383:CWOE RS32615
gene id: 469383:CWOE_RS32615
uniprot id: D3F063
names: Similarity
messages: Belongs to the BolA/IbaG family.

469383:CWOE RS19985
gene id: 469383:CWOE_RS19985
uniprot id: D3F3N8
names: Similarity
messages: Belongs to the FGGY kinase family.

469383:CWOE RS24660
gene id: 469383:CWOE_RS24660
uniprot id: D3FC29
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

469383:CWOE RS11595
gene id: 469383:CWOE_RS11595
uniprot id: D3F6I4
names: Similarity
messages: Belongs to the CdaR family.

469383:CWOE RS25720
gene id: 469383:CWOE_RS25720
uniprot id: D3FDE4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS00015
gene id: 469383:CWOE_RS00015
uniprot id: D3EYQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

469383:CWOE RS15875
gene id: 469383:CWOE_RS15875
uniprot id: D3FDY3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

469383:CWOE RS07455
gene id: 469383:CWOE_RS07455
uniprot id: D3EZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS25750
gene id: 469383:CWOE_RS25750
uniprot id: D3FDF0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS31385
gene id: 469383:CWOE_RS31385
uniprot id: D3FC35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

469383:CWOE RS17850
gene id: 469383:CWOE_RS17850
uniprot id: D3F0C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

469383:CWOE RS00465
gene id: 469383:CWOE_RS00465
uniprot id: D3F444
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

469383:CWOE RS22640
gene id: 469383:CWOE_RS22640
uniprot id: D3F828
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS14245
gene id: 469383:CWOE_RS14245
uniprot id: D3FAW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS21280
gene id: 469383:CWOE_RS21280
uniprot id: D3F5V5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

469383:CWOE RS14670
gene id: 469383:CWOE_RS14670
uniprot id: D3FBU5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

469383:CWOE RS28675
gene id: 469383:CWOE_RS28675
uniprot id: D3F1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS22560
gene id: 469383:CWOE_RS22560
uniprot id: D3F813
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

469383:CWOE RS20660
gene id: 469383:CWOE_RS20660
uniprot id: D3F4S6
names: Similarity
messages: Belongs to the CdaR family.

469383:CWOE RS25020
gene id: 469383:CWOE_RS25020
uniprot id: D3FCA2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

469383:CWOE RS06625
gene id: 469383:CWOE_RS06625
uniprot id: D3FES8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

469383:CWOE RS06965
gene id: 469383:CWOE_RS06965
uniprot id: D3EYU5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

469383:CWOE RS01770
gene id: 469383:CWOE_RS01770
uniprot id: D3F717
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS25940
gene id: 469383:CWOE_RS25940
uniprot id: D3FE88
names: Similarity
messages: Belongs to the peptidase S13 family.

469383:CWOE RS10780
gene id: 469383:CWOE_RS10780
uniprot id: D3F5C0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469383:CWOE RS00915
gene id: 469383:CWOE_RS00915
uniprot id: D3F541
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

469383:CWOE RS19520
gene id: 469383:CWOE_RS19520
uniprot id: D3F3E9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS17620
gene id: 469383:CWOE_RS17620
uniprot id: D3F085
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

469383:CWOE RS17725
gene id: 469383:CWOE_RS17725
uniprot id: D3F0A3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

469383:CWOE RS06915
gene id: 469383:CWOE_RS06915
uniprot id: D3EYT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS11025
gene id: 469383:CWOE_RS11025
uniprot id: D3F5G9
names: Similarity
messages: Belongs to the creatininase superfamily.

469383:CWOE RS12065
gene id: 469383:CWOE_RS12065
uniprot id: D3F7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS14825
gene id: 469383:CWOE_RS14825
uniprot id: D3FBX6
names: Similarity
messages: Belongs to the DtxR/MntR family.

469383:CWOE RS13220
gene id: 469383:CWOE_RS13220
uniprot id: D3F9K9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

469383:CWOE RS23245
gene id: 469383:CWOE_RS23245
uniprot id: D3F946
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS05955
gene id: 469383:CWOE_RS05955
uniprot id: D3FDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS12645
gene id: 469383:CWOE_RS12645
uniprot id: D3F8J4
names: Similarity
messages: Belongs to the HupF/HypC family.

469383:CWOE RS29590
gene id: 469383:CWOE_RS29590
uniprot id: D3F3R8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS30925
gene id: 469383:CWOE_RS30925
uniprot id: D3F083
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

469383:CWOE RS02945
gene id: 469383:CWOE_RS02945
uniprot id: D3F8F2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00415
gene id: 469383:CWOE_RS00415
uniprot id: D3F434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UppP family.
messages: Membrane

469383:CWOE RS09390
gene id: 469383:CWOE_RS09390
uniprot id: D3F330
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS08640
gene id: 469383:CWOE_RS08640
uniprot id: D3F182
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

469383:CWOE RS17130
gene id: 469383:CWOE_RS17130
uniprot id: D3EZ83
names: Similarity
messages: Belongs to the type IB topoisomerase family.

469383:CWOE RS03720
gene id: 469383:CWOE_RS03720
uniprot id: D3FAA9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

469383:CWOE RS00350
gene id: 469383:CWOE_RS00350
uniprot id: D3F422
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

469383:CWOE RS00030
gene id: 469383:CWOE_RS00030
uniprot id: D3EYQ8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

469383:CWOE RS26285
gene id: 469383:CWOE_RS26285
uniprot id: D3FEF2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

469383:CWOE RS07725
gene id: 469383:CWOE_RS07725
uniprot id: D3EZZ8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

469383:CWOE RS00440
gene id: 469383:CWOE_RS00440
uniprot id: D3F439
names: Similarity
messages: Belongs to the polysaccharide synthase family.

469383:CWOE RS04500
gene id: 469383:CWOE_RS04500
uniprot id: D3FBG4
names: Similarity
messages: Belongs to the P(II) protein family.

469383:CWOE RS03835
gene id: 469383:CWOE_RS03835
uniprot id: D3FAD2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

469383:CWOE RS11695
gene id: 469383:CWOE_RS11695
uniprot id: D3F6K4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469383:CWOE RS06025
gene id: 469383:CWOE_RS06025
uniprot id: D3FDQ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469383:CWOE RS16595
gene id: 469383:CWOE_RS16595
uniprot id: D3FF25
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS21855
gene id: 469383:CWOE_RS21855
uniprot id: D3F6X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

469383:CWOE RS27355
gene id: 469383:CWOE_RS27355
uniprot id: D3EZL3
names: Similarity
messages: Belongs to the TPP enzyme family.

469383:CWOE RS16480
gene id: 469383:CWOE_RS16480
uniprot id: D3FF02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

469383:CWOE RS17650
gene id: 469383:CWOE_RS17650
uniprot id: D3F091
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

469383:CWOE RS09305
gene id: 469383:CWOE_RS09305
uniprot id: D3F312
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

469383:CWOE RS02120
gene id: 469383:CWOE_RS02120
uniprot id: D3F789
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

469383:CWOE RS23770
gene id: 469383:CWOE_RS23770
uniprot id: D3FA49
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS07605
gene id: 469383:CWOE_RS07605
uniprot id: D3EZX3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS29560
gene id: 469383:CWOE_RS29560
uniprot id: D3F307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS29445
gene id: 469383:CWOE_RS29445
uniprot id: D3F2Y4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

469383:CWOE RS21455
gene id: 469383:CWOE_RS21455
uniprot id: D3F6P1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

469383:CWOE RS30805
gene id: 469383:CWOE_RS30805
uniprot id: D3FE47
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

469383:CWOE RS17580
gene id: 469383:CWOE_RS17580
uniprot id: D3F077
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

469383:CWOE RS08945
gene id: 469383:CWOE_RS08945
uniprot id: D3F243
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

469383:CWOE RS13720
gene id: 469383:CWOE_RS13720
uniprot id: D3F9V8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

469383:CWOE RS25305
gene id: 469383:CWOE_RS25305
uniprot id: D3FD62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS22570
gene id: 469383:CWOE_RS22570
uniprot id: D3F815
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

469383:CWOE RS28870
gene id: 469383:CWOE_RS28870
uniprot id: D3F1W9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS17705
gene id: 469383:CWOE_RS17705
uniprot id: D3F099
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS17655
gene id: 469383:CWOE_RS17655
uniprot id: D3F092
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS23155
gene id: 469383:CWOE_RS23155
uniprot id: D3F928
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

469383:CWOE RS01550
gene id: 469383:CWOE_RS01550
uniprot id: D3F671
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS18985
gene id: 469383:CWOE_RS18985
uniprot id: D3F2E1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

469383:CWOE RS07085
gene id: 469383:CWOE_RS07085
uniprot id: D3EYX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

469383:CWOE RS16115
gene id: 469383:CWOE_RS16115
uniprot id: D3FE30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

469383:CWOE RS18885
gene id: 469383:CWOE_RS18885
uniprot id: D3F2C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

469383:CWOE RS18445
gene id: 469383:CWOE_RS18445
uniprot id: D3F1D9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS14505
gene id: 469383:CWOE_RS14505
uniprot id: D3FBR2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS31770
gene id: 469383:CWOE_RS31770
uniprot id: D3F3V8
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS06300
gene id: 469383:CWOE_RS06300
uniprot id: D3FEL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

469383:CWOE RS04795
gene id: 469383:CWOE_RS04795
uniprot id: D3FBM3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469383:CWOE RS18915
gene id: 469383:CWOE_RS18915
uniprot id: D3F2C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

469383:CWOE RS31285
gene id: 469383:CWOE_RS31285
uniprot id: D3F8Y3
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

469383:CWOE RS17745
gene id: 469383:CWOE_RS17745
uniprot id: D3F0A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

469383:CWOE RS12760
gene id: 469383:CWOE_RS12760
uniprot id: D3F8L6
names: Similarity
messages: Belongs to the peptidase S58 family.

469383:CWOE RS19365
gene id: 469383:CWOE_RS19365
uniprot id: D3F2L7
names: Similarity
messages: Belongs to the CdaR family.

469383:CWOE RS18890
gene id: 469383:CWOE_RS18890
uniprot id: D3F2C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

469383:CWOE RS26300
gene id: 469383:CWOE_RS26300
uniprot id: D3FEF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

469383:CWOE RS13410
gene id: 469383:CWOE_RS13410
uniprot id: D3F9P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

469383:CWOE RS01005
gene id: 469383:CWOE_RS01005
uniprot id: D3F559
names: Similarity
messages: Belongs to the peptidase S51 family.

469383:CWOE RS10545
gene id: 469383:CWOE_RS10545
uniprot id: D3F4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS22420
gene id: 469383:CWOE_RS22420
uniprot id: D3F7Y6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS33885
gene id: 469383:CWOE_RS33885
uniprot id: D3EZ70
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469383:CWOE RS15330
gene id: 469383:CWOE_RS15330
uniprot id: D3FCX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

469383:CWOE RS23250
gene id: 469383:CWOE_RS23250
uniprot id: D3F947
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS31530
gene id: 469383:CWOE_RS31530
uniprot id: D3FEH9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

469383:CWOE RS31455
gene id: 469383:CWOE_RS31455
uniprot id: D3FD67
names: Similarity
messages: Belongs to the peptidase S33 family.

469383:CWOE RS13555
gene id: 469383:CWOE_RS13555
uniprot id: D3F9S5
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS20060
gene id: 469383:CWOE_RS20060
uniprot id: D3F3Q3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469383:CWOE RS30505
gene id: 469383:CWOE_RS30505
uniprot id: D3F294
names: Similarity
messages: Belongs to the SCO1/2 family.

469383:CWOE RS23555
gene id: 469383:CWOE_RS23555
uniprot id: D3FA08
names: Similarity
messages: Belongs to the LacAB/RpiB family.

469383:CWOE RS04060
gene id: 469383:CWOE_RS04060
uniprot id: D3FAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS01000
gene id: 469383:CWOE_RS01000
uniprot id: D3F558
names: Similarity
messages: Belongs to the peptidase S51 family.

469383:CWOE RS20545
gene id: 469383:CWOE_RS20545
uniprot id: D3F4Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS25585
gene id: 469383:CWOE_RS25585
uniprot id: D3FDB7
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS11880
gene id: 469383:CWOE_RS11880
uniprot id: D3F7E6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

469383:CWOE RS27055
gene id: 469383:CWOE_RS27055
uniprot id: D3FFK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

469383:CWOE RS30010
gene id: 469383:CWOE_RS30010
uniprot id: D3F729
names: Similarity
messages: Belongs to the prespore-cell-inducing factor family.

469383:CWOE RS13960
gene id: 469383:CWOE_RS13960
uniprot id: D3FAQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS33840
gene id: 469383:CWOE_RS33840
uniprot id: D3F451
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS05085
gene id: 469383:CWOE_RS05085
uniprot id: D3FCH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS23175
gene id: 469383:CWOE_RS23175
uniprot id: D3F932
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

469383:CWOE RS13690
gene id: 469383:CWOE_RS13690
uniprot id: D3F9V2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS21700
gene id: 469383:CWOE_RS21700
uniprot id: D3F6U1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS25660
gene id: 469383:CWOE_RS25660
uniprot id: D3FDD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS17535
gene id: 469383:CWOE_RS17535
uniprot id: D3F068
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS00935
gene id: 469383:CWOE_RS00935
uniprot id: D3F545
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS23330
gene id: 469383:CWOE_RS23330
uniprot id: D3F963
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS28355
gene id: 469383:CWOE_RS28355
uniprot id: D3F0W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

469383:CWOE RS22175
gene id: 469383:CWOE_RS22175
uniprot id: D3F7T9
names: Similarity
messages: Belongs to the cytochrome P450 family.

469383:CWOE RS10505
gene id: 469383:CWOE_RS10505
uniprot id: D3F4G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS09415
gene id: 469383:CWOE_RS09415
uniprot id: D3F335
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

469383:CWOE RS11805
gene id: 469383:CWOE_RS11805
uniprot id: D3F6M6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS30660
gene id: 469383:CWOE_RS30660
uniprot id: D3F9L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

469383:CWOE RS02095
gene id: 469383:CWOE_RS02095
uniprot id: D3F784
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS15785
gene id: 469383:CWOE_RS15785
uniprot id: D3FDW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

469383:CWOE RS27720
gene id: 469383:CWOE_RS27720
uniprot id: D3EZT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

469383:CWOE RS17950
gene id: 469383:CWOE_RS17950
uniprot id: D3F0E7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

469383:CWOE RS29875
gene id: 469383:CWOE_RS29875
uniprot id: D3F3X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

469383:CWOE RS10610
gene id: 469383:CWOE_RS10610
uniprot id: D3F586
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

469383:CWOE RS00685
gene id: 469383:CWOE_RS00685
uniprot id: D3F4Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

469383:CWOE RS05410
gene id: 469383:CWOE_RS05410
uniprot id: D3FCP0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

469383:CWOE RS12505
gene id: 469383:CWOE_RS12505
uniprot id: D3F8G6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS14260
gene id: 469383:CWOE_RS14260
uniprot id: D3FAW4
names: Similarity
messages: Belongs to the TrpF family.

469383:CWOE RS05080
gene id: 469383:CWOE_RS05080
uniprot id: D3FCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS01520
gene id: 469383:CWOE_RS01520
uniprot id: D3F665
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS16255
gene id: 469383:CWOE_RS16255
uniprot id: D3FE57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469383:CWOE RS03540
gene id: 469383:CWOE_RS03540
uniprot id: D3F9H5
names: Similarity
messages: Belongs to the universal stress protein A family.

469383:CWOE RS02440
gene id: 469383:CWOE_RS02440
uniprot id: D3F852
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS03265
gene id: 469383:CWOE_RS03265
uniprot id: D3F9C2
names: Similarity
messages: Belongs to the arginase family.

469383:CWOE RS03245
gene id: 469383:CWOE_RS03245
uniprot id: D3F9B7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

469383:CWOE RS04065
gene id: 469383:CWOE_RS04065
uniprot id: D3FAH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS13850
gene id: 469383:CWOE_RS13850
uniprot id: D3FAN3
names: Similarity
messages: Belongs to the histone deacetylase family.

469383:CWOE RS11420
gene id: 469383:CWOE_RS11420
uniprot id: D3F6F0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS04545
gene id: 469383:CWOE_RS04545
uniprot id: D3FBH3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

469383:CWOE RS16690
gene id: 469383:CWOE_RS16690
uniprot id: D3FF43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS29965
gene id: 469383:CWOE_RS29965
uniprot id: D3F517
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

469383:CWOE RS28820
gene id: 469383:CWOE_RS28820
uniprot id: D3F1V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

469383:CWOE RS19460
gene id: 469383:CWOE_RS19460
uniprot id: D3F2N6
names: Function
messages: Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.

469383:CWOE RS08610
gene id: 469383:CWOE_RS08610
uniprot id: D3F176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

469383:CWOE RS22320
gene id: 469383:CWOE_RS22320
uniprot id: D3F7W7
names: Similarity
messages: Belongs to the IlvD/Edd family.

469383:CWOE RS03225
gene id: 469383:CWOE_RS03225
uniprot id: D3F9B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

469383:CWOE RS09050
gene id: 469383:CWOE_RS09050
uniprot id: D3F265
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

469383:CWOE RS18480
gene id: 469383:CWOE_RS18480
uniprot id: D3F1E6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

469383:CWOE RS29880
gene id: 469383:CWOE_RS29880
uniprot id: D3F3X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

469383:CWOE RS14145
gene id: 469383:CWOE_RS14145
uniprot id: D3FAU1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

469383:CWOE RS01910
gene id: 469383:CWOE_RS01910
uniprot id: D3F745
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

469383:CWOE RS06690
gene id: 469383:CWOE_RS06690
uniprot id: D3FEU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

469383:CWOE RS15925
gene id: 469383:CWOE_RS15925
uniprot id: D3FDZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

469383:CWOE RS03165
gene id: 469383:CWOE_RS03165
uniprot id: D3F9A1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

469383:CWOE RS19650
gene id: 469383:CWOE_RS19650
uniprot id: D3F3H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

469383:CWOE RS07520
gene id: 469383:CWOE_RS07520
uniprot id: D3EZV6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469383:CWOE RS11515
gene id: 469383:CWOE_RS11515
uniprot id: D3F6G9
names: Similarity
messages: Belongs to the peptidase S9C family.

469383:CWOE RS23140
gene id: 469383:CWOE_RS23140
uniprot id: D3F925
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS05005
gene id: 469383:CWOE_RS05005
uniprot id: D3FCG1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS11040
gene id: 469383:CWOE_RS11040
uniprot id: D3F5H2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00390
gene id: 469383:CWOE_RS00390
uniprot id: D3F429
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

469383:CWOE RS02425
gene id: 469383:CWOE_RS02425
uniprot id: D3F849
names: Similarity
messages: Belongs to the AHA1 family.

469383:CWOE RS14405
gene id: 469383:CWOE_RS14405
uniprot id: D3FBP2
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

469383:CWOE RS06770
gene id: 469383:CWOE_RS06770
uniprot id: D3FEV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

469383:CWOE RS15425
gene id: 469383:CWOE_RS15425
uniprot id: D3FCZ8
names: Similarity
messages: Belongs to the phosphopentomutase family.

469383:CWOE RS06255
gene id: 469383:CWOE_RS06255
uniprot id: D3FEK3
names: Similarity
messages: Belongs to the creatininase superfamily.

469383:CWOE RS10500
gene id: 469383:CWOE_RS10500
uniprot id: D3F4F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS13795
gene id: 469383:CWOE_RS13795
uniprot id: D3FAM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS09335
gene id: 469383:CWOE_RS09335
uniprot id: D3F319
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

469383:CWOE RS09795
gene id: 469383:CWOE_RS09795
uniprot id: D3F3B2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS21090
gene id: 469383:CWOE_RS21090
uniprot id: D3F5R9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS02010
gene id: 469383:CWOE_RS02010
uniprot id: D3F766
names: Similarity
messages: Belongs to the cytochrome P450 family.

469383:CWOE RS13315
gene id: 469383:CWOE_RS13315
uniprot id: D3F9M8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

469383:CWOE RS33685
gene id: 469383:CWOE_RS33685
uniprot id: D3FDB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS27880
gene id: 469383:CWOE_RS27880
uniprot id: D3F0M2
names: Similarity
messages: Belongs to the YciI family.

469383:CWOE RS26440
gene id: 469383:CWOE_RS26440
uniprot id: D3FEI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS24490
gene id: 469383:CWOE_RS24490
uniprot id: D3FB98
names: Similarity
messages: Belongs to the DSD1 family.

469383:CWOE RS09935
gene id: 469383:CWOE_RS09935
uniprot id: D3F447
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS33790
gene id: 469383:CWOE_RS33790
uniprot id: D3FES6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

469383:CWOE RS23085
gene id: 469383:CWOE_RS23085
uniprot id: D3F914
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

469383:CWOE RS10230
gene id: 469383:CWOE_RS10230
uniprot id: D3F4A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS22650
gene id: 469383:CWOE_RS22650
uniprot id: D3F830
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS23300
gene id: 469383:CWOE_RS23300
uniprot id: D3F957
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

469383:CWOE RS11680
gene id: 469383:CWOE_RS11680
uniprot id: D3F6K1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS26520
gene id: 469383:CWOE_RS26520
uniprot id: D3FF97
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

469383:CWOE RS09220
gene id: 469383:CWOE_RS09220
uniprot id: D3F2A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

469383:CWOE RS31740
gene id: 469383:CWOE_RS31740
uniprot id: D3F2Z0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS26500
gene id: 469383:CWOE_RS26500
uniprot id: D3FF93
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

469383:CWOE RS01815
gene id: 469383:CWOE_RS01815
uniprot id: D3F726
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS02175
gene id: 469383:CWOE_RS02175
uniprot id: D3F7A0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

469383:CWOE RS15960
gene id: 469383:CWOE_RS15960
uniprot id: D3FDZ9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

469383:CWOE RS03805
gene id: 469383:CWOE_RS03805
uniprot id: D3FAC6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS14350
gene id: 469383:CWOE_RS14350
uniprot id: D3FAY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

469383:CWOE RS11500
gene id: 469383:CWOE_RS11500
uniprot id: D3F6G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS23165
gene id: 469383:CWOE_RS23165
uniprot id: D3F930
names: Similarity
messages: Belongs to the PGI/PMI family.

469383:CWOE RS30415
gene id: 469383:CWOE_RS30415
uniprot id: D3F065
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS19015
gene id: 469383:CWOE_RS19015
uniprot id: D3F2E7
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

469383:CWOE RS03755
gene id: 469383:CWOE_RS03755
uniprot id: D3FAB6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS28845
gene id: 469383:CWOE_RS28845
uniprot id: D3F1W4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

469383:CWOE RS07395
gene id: 469383:CWOE_RS07395
uniprot id: D3EZ33
names: Similarity
messages: Belongs to the AHA1 family.

469383:CWOE RS13205
gene id: 469383:CWOE_RS13205
uniprot id: D3F9K6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

469383:CWOE RS12480
gene id: 469383:CWOE_RS12480
uniprot id: D3F7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS11955
gene id: 469383:CWOE_RS11955
uniprot id: D3F7G0
names: Caution
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

469383:CWOE RS27445
gene id: 469383:CWOE_RS27445
uniprot id: D3EZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

469383:CWOE RS17715
gene id: 469383:CWOE_RS17715
uniprot id: D3F0A1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

469383:CWOE RS03870
gene id: 469383:CWOE_RS03870
uniprot id: D3FAD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

469383:CWOE RS01660
gene id: 469383:CWOE_RS01660
uniprot id: D3F693
names: Similarity
messages: Belongs to the HSP15 family.

469383:CWOE RS28110
gene id: 469383:CWOE_RS28110
uniprot id: D3F0R7
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS27360
gene id: 469383:CWOE_RS27360
uniprot id: D3EZL4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

469383:CWOE RS02965
gene id: 469383:CWOE_RS02965
uniprot id: D3F8F6
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

469383:CWOE RS15590
gene id: 469383:CWOE_RS15590
uniprot id: D3FD30
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

469383:CWOE RS14290
gene id: 469383:CWOE_RS14290
uniprot id: D3FAX1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

469383:CWOE RS22110
gene id: 469383:CWOE_RS22110
uniprot id: D3F7S6
names: Similarity
messages: Belongs to the glutamine synthetase family.

469383:CWOE RS29145
gene id: 469383:CWOE_RS29145
uniprot id: D3F2S4
names: Similarity
messages: Belongs to the FPG family.

469383:CWOE RS10140
gene id: 469383:CWOE_RS10140
uniprot id: D3F489
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

469383:CWOE RS02185
gene id: 469383:CWOE_RS02185
uniprot id: D3F7A2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS16225
gene id: 469383:CWOE_RS16225
uniprot id: D3FE51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

469383:CWOE RS27945
gene id: 469383:CWOE_RS27945
uniprot id: D3F0N5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

469383:CWOE RS14650
gene id: 469383:CWOE_RS14650
uniprot id: D3FBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS08220
gene id: 469383:CWOE_RS08220
uniprot id: D3F0Z9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS06190
gene id: 469383:CWOE_RS06190
uniprot id: D3FEJ0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS06735
gene id: 469383:CWOE_RS06735
uniprot id: D3FEU9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

469383:CWOE RS25005
gene id: 469383:CWOE_RS25005
uniprot id: D3FC99
names: Similarity
messages: Belongs to the UPF0045 family.

469383:CWOE RS20900
gene id: 469383:CWOE_RS20900
uniprot id: D3F5N1
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

469383:CWOE RS26470
gene id: 469383:CWOE_RS26470
uniprot id: D3FF87
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

469383:CWOE RS20520
gene id: 469383:CWOE_RS20520
uniprot id: D3F4P8
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

469383:CWOE RS08340
gene id: 469383:CWOE_RS08340
uniprot id: D3F123
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

469383:CWOE RS02855
gene id: 469383:CWOE_RS02855
uniprot id: D3F8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS04230
gene id: 469383:CWOE_RS04230
uniprot id: D3FAL0
names: Similarity
messages: Belongs to the cytochrome P450 family.

469383:CWOE RS16845
gene id: 469383:CWOE_RS16845
uniprot id: D3FF74
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

469383:CWOE RS17605
gene id: 469383:CWOE_RS17605
uniprot id: D3F082
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

469383:CWOE RS00495
gene id: 469383:CWOE_RS00495
uniprot id: D3F4V5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

469383:CWOE RS19635
gene id: 469383:CWOE_RS19635
uniprot id: D3F3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.
messages: Cytoplasm

469383:CWOE RS00460
gene id: 469383:CWOE_RS00460
uniprot id: D3F443
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

469383:CWOE RS24840
gene id: 469383:CWOE_RS24840
uniprot id: D3FC65
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS19350
gene id: 469383:CWOE_RS19350
uniprot id: D3F2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS19355
gene id: 469383:CWOE_RS19355
uniprot id: D3F2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS21335
gene id: 469383:CWOE_RS21335
uniprot id: D3F5W6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

469383:CWOE RS10850
gene id: 469383:CWOE_RS10850
uniprot id: D3F5D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS28745
gene id: 469383:CWOE_RS28745
uniprot id: D3F1U4
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS06030
gene id: 469383:CWOE_RS06030
uniprot id: D3FDQ9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS20935
gene id: 469383:CWOE_RS20935
uniprot id: D3F5N8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS21600
gene id: 469383:CWOE_RS21600
uniprot id: D3F6S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

469383:CWOE RS26595
gene id: 469383:CWOE_RS26595
uniprot id: D3FFB2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

469383:CWOE RS08565
gene id: 469383:CWOE_RS08565
uniprot id: D3F167
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

469383:CWOE RS18085
gene id: 469383:CWOE_RS18085
uniprot id: D3F0H3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

469383:CWOE RS08950
gene id: 469383:CWOE_RS08950
uniprot id: D3F244
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

469383:CWOE RS16010
gene id: 469383:CWOE_RS16010
uniprot id: D3FE09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

469383:CWOE RS06555
gene id: 469383:CWOE_RS06555
uniprot id: D3FER3
names: Similarity
messages: Belongs to the fructosamine kinase family.

469383:CWOE RS07385
gene id: 469383:CWOE_RS07385
uniprot id: D3EZ30
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS26795
gene id: 469383:CWOE_RS26795
uniprot id: D3FFF1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS04895
gene id: 469383:CWOE_RS04895
uniprot id: D3FCD9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS29780
gene id: 469383:CWOE_RS29780
uniprot id: D3F3V5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS27340
gene id: 469383:CWOE_RS27340
uniprot id: D3EZL0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

469383:CWOE RS26320
gene id: 469383:CWOE_RS26320
uniprot id: D3FEF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

469383:CWOE RS01010
gene id: 469383:CWOE_RS01010
uniprot id: D3F560
names: Similarity
messages: Belongs to the cytochrome P450 family.

469383:CWOE RS15880
gene id: 469383:CWOE_RS15880
uniprot id: D3FDY4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

469383:CWOE RS20210
gene id: 469383:CWOE_RS20210
uniprot id: D3F4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS04800
gene id: 469383:CWOE_RS04800
uniprot id: D3FBM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS22615
gene id: 469383:CWOE_RS22615
uniprot id: D3F823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

469383:CWOE RS29950
gene id: 469383:CWOE_RS29950
uniprot id: D3F4V7
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

469383:CWOE RS29070
gene id: 469383:CWOE_RS29070
uniprot id: D3F2Q9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

469383:CWOE RS26165
gene id: 469383:CWOE_RS26165
uniprot id: D3FEC8
names: Similarity
messages: Belongs to the UPF0235 family.

469383:CWOE RS01850
gene id: 469383:CWOE_RS01850
uniprot id: D3F733
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS30360
gene id: 469383:CWOE_RS30360
uniprot id: D3EZ13
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

469383:CWOE RS10925
gene id: 469383:CWOE_RS10925
uniprot id: D3F5E9
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

469383:CWOE RS09080
gene id: 469383:CWOE_RS09080
uniprot id: D3F271
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-binding monooxygenase family.
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

469383:CWOE RS05610
gene id: 469383:CWOE_RS05610
uniprot id: D3FDH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS04855
gene id: 469383:CWOE_RS04855
uniprot id: D3FBN5
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS30485
gene id: 469383:CWOE_RS30485
uniprot id: D3F253
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS04000
gene id: 469383:CWOE_RS04000
uniprot id: D3FAG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

469383:CWOE RS01720
gene id: 469383:CWOE_RS01720
uniprot id: D3F6A5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS15930
gene id: 469383:CWOE_RS15930
uniprot id: D3FDZ4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

469383:CWOE RS10865
gene id: 469383:CWOE_RS10865
uniprot id: D3F5D7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

469383:CWOE RS06110
gene id: 469383:CWOE_RS06110
uniprot id: D3FDS4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

469383:CWOE RS09740
gene id: 469383:CWOE_RS09740
uniprot id: D3F3A1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

469383:CWOE RS13310
gene id: 469383:CWOE_RS13310
uniprot id: D3F9M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS00750
gene id: 469383:CWOE_RS00750
uniprot id: D3F506
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS06725
gene id: 469383:CWOE_RS06725
uniprot id: D3FEU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

469383:CWOE RS00865
gene id: 469383:CWOE_RS00865
uniprot id: D3F531
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS31440
gene id: 469383:CWOE_RS31440
uniprot id: D3FD50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

469383:CWOE RS20915
gene id: 469383:CWOE_RS20915
uniprot id: D3F5N4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS05560
gene id: 469383:CWOE_RS05560
uniprot id: D3FDG9
names: Similarity
messages: Belongs to the FPG family.

469383:CWOE RS23075
gene id: 469383:CWOE_RS23075
uniprot id: D3F912
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

469383:CWOE RS31445
gene id: 469383:CWOE_RS31445
uniprot id: D3FD51
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS21555
gene id: 469383:CWOE_RS21555
uniprot id: D3F6R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

469383:CWOE RS21540
gene id: 469383:CWOE_RS21540
uniprot id: D3F6Q9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS26370
gene id: 469383:CWOE_RS26370
uniprot id: D3FEG8
names: Similarity
messages: Belongs to the CdaR family.

469383:CWOE RS22855
gene id: 469383:CWOE_RS22855
uniprot id: D3F8W9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

469383:CWOE RS08860
gene id: 469383:CWOE_RS08860
uniprot id: D3F225
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

469383:CWOE RS26685
gene id: 469383:CWOE_RS26685
uniprot id: D3FFD1
names: Similarity
messages: Belongs to the asparagine synthetase family.

469383:CWOE RS06675
gene id: 469383:CWOE_RS06675
uniprot id: D3FET7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS04495
gene id: 469383:CWOE_RS04495
uniprot id: D3FBG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS29690
gene id: 469383:CWOE_RS29690
uniprot id: D3F3T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

469383:CWOE RS23810
gene id: 469383:CWOE_RS23810
uniprot id: D3FA57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS29320
gene id: 469383:CWOE_RS29320
uniprot id: D3F2V9
names: Similarity
messages: Belongs to the thioredoxin family.

469383:CWOE RS31235
gene id: 469383:CWOE_RS31235
uniprot id: D3F7X7
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

469383:CWOE RS13910
gene id: 469383:CWOE_RS13910
uniprot id: D3FAP5
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS09770
gene id: 469383:CWOE_RS09770
uniprot id: D3F3A7
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00975
gene id: 469383:CWOE_RS00975
uniprot id: D3F553
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469383:CWOE RS06170
gene id: 469383:CWOE_RS06170
uniprot id: D3FDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS14250
gene id: 469383:CWOE_RS14250
uniprot id: D3FAW2
names: Similarity
messages: Belongs to the TrpC family.

469383:CWOE RS01955
gene id: 469383:CWOE_RS01955
uniprot id: D3F754
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

469383:CWOE RS06645
gene id: 469383:CWOE_RS06645
uniprot id: D3FET1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

469383:CWOE RS21230
gene id: 469383:CWOE_RS21230
uniprot id: D3F5U5
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

469383:CWOE RS28530
gene id: 469383:CWOE_RS28530
uniprot id: D3F1Q3
names: Similarity
messages: Belongs to the peptidase S33 family.

469383:CWOE RS14415
gene id: 469383:CWOE_RS14415
uniprot id: D3FBP4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

469383:CWOE RS00160
gene id: 469383:CWOE_RS00160
uniprot id: D3F3Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

469383:CWOE RS20355
gene id: 469383:CWOE_RS20355
uniprot id: D3F4L7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

469383:CWOE RS10860
gene id: 469383:CWOE_RS10860
uniprot id: D3F5D6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

469383:CWOE RS30575
gene id: 469383:CWOE_RS30575
uniprot id: D3F5G3
names: Similarity
messages: Belongs to the CdaR family.

469383:CWOE RS10475
gene id: 469383:CWOE_RS10475
uniprot id: D3F4F4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS20805
gene id: 469383:CWOE_RS20805
uniprot id: D3F5L3
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

469383:CWOE RS13320
gene id: 469383:CWOE_RS13320
uniprot id: D3F9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

469383:CWOE RS16220
gene id: 469383:CWOE_RS16220
uniprot id: D3FE50
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

469383:CWOE RS29185
gene id: 469383:CWOE_RS29185
uniprot id: D3F2T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

469383:CWOE RS26965
gene id: 469383:CWOE_RS26965
uniprot id: D3FFI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS31300
gene id: 469383:CWOE_RS31300
uniprot id: D3F933
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

469383:CWOE RS15865
gene id: 469383:CWOE_RS15865
uniprot id: D3FDY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

469383:CWOE RS11335
gene id: 469383:CWOE_RS11335
uniprot id: D3F6D2
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

469383:CWOE RS12705
gene id: 469383:CWOE_RS12705
uniprot id: D3F8K6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

469383:CWOE RS18695
gene id: 469383:CWOE_RS18695
uniprot id: D3F1I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

469383:CWOE RS00385
gene id: 469383:CWOE_RS00385
uniprot id: D3F428
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

469383:CWOE RS11085
gene id: 469383:CWOE_RS11085
uniprot id: D3F5I1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

469383:CWOE RS22000
gene id: 469383:CWOE_RS22000
uniprot id: D3F700
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

469383:CWOE RS18210
gene id: 469383:CWOE_RS18210
uniprot id: D3F191
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

469383:CWOE RS22195
gene id: 469383:CWOE_RS22195
uniprot id: D3F7U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS17305
gene id: 469383:CWOE_RS17305
uniprot id: D3EZB7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

469383:CWOE RS26235
gene id: 469383:CWOE_RS26235
uniprot id: D3FEE1
names: Similarity
messages: Belongs to the UPF0173 family.

469383:CWOE RS20290
gene id: 469383:CWOE_RS20290
uniprot id: D3F4K6
names: Similarity
messages: Belongs to the TPP enzyme family.

469383:CWOE RS15055
gene id: 469383:CWOE_RS15055
uniprot id: D3FCS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS02035
gene id: 469383:CWOE_RS02035
uniprot id: D3F771
names: Similarity
messages: Belongs to the AIR synthase family.

469383:CWOE RS33910
gene id: 469383:CWOE_RS33910
uniprot id: D3F5U6
names: Similarity
messages: Belongs to the RutC family.

469383:CWOE RS05345
gene id: 469383:CWOE_RS05345
uniprot id: D3FCM7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

469383:CWOE RS22135
gene id: 469383:CWOE_RS22135
uniprot id: D3F7T1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

469383:CWOE RS06935
gene id: 469383:CWOE_RS06935
uniprot id: D3EYU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS21200
gene id: 469383:CWOE_RS21200
uniprot id: D3F5T9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS29905
gene id: 469383:CWOE_RS29905
uniprot id: D3EYQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

469383:CWOE RS26505
gene id: 469383:CWOE_RS26505
uniprot id: D3FF94
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS26415
gene id: 469383:CWOE_RS26415
uniprot id: D3FEH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

469383:CWOE RS25275
gene id: 469383:CWOE_RS25275
uniprot id: D3FD56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS05445
gene id: 469383:CWOE_RS05445
uniprot id: D3FCP7
names: Similarity
messages: Belongs to the citrate synthase family.

469383:CWOE RS01055
gene id: 469383:CWOE_RS01055
uniprot id: D3F569
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

469383:CWOE RS00475
gene id: 469383:CWOE_RS00475
uniprot id: D3F446
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS29710
gene id: 469383:CWOE_RS29710
uniprot id: D3F3U1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

469383:CWOE RS28520
gene id: 469383:CWOE_RS28520
uniprot id: D3F1Q1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS21465
gene id: 469383:CWOE_RS21465
uniprot id: D3F6P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS11860
gene id: 469383:CWOE_RS11860
uniprot id: D3F7E2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

469383:CWOE RS09595
gene id: 469383:CWOE_RS09595
uniprot id: D3F372
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

469383:CWOE RS05775
gene id: 469383:CWOE_RS05775
uniprot id: D3FDL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

469383:CWOE RS09725
gene id: 469383:CWOE_RS09725
uniprot id: D3F398
names: Similarity
messages: Belongs to the cytochrome P450 family.

469383:CWOE RS14220
gene id: 469383:CWOE_RS14220
uniprot id: D3FAV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

469383:CWOE RS15080
gene id: 469383:CWOE_RS15080
uniprot id: D3FCS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

469383:CWOE RS17595
gene id: 469383:CWOE_RS17595
uniprot id: D3F080
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

469383:CWOE RS18440
gene id: 469383:CWOE_RS18440
uniprot id: D3F1D8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

469383:CWOE RS04710
gene id: 469383:CWOE_RS04710
uniprot id: D3FBK6
names: Similarity
messages: Belongs to the universal stress protein A family.

469383:CWOE RS03550
gene id: 469383:CWOE_RS03550
uniprot id: D3F9H7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

469383:CWOE RS14495
gene id: 469383:CWOE_RS14495
uniprot id: D3FBR0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00035
gene id: 469383:CWOE_RS00035
uniprot id: D3EYQ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

469383:CWOE RS27260
gene id: 469383:CWOE_RS27260
uniprot id: D3EZJ3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

469383:CWOE RS10820
gene id: 469383:CWOE_RS10820
uniprot id: D3F5C8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

469383:CWOE RS26715
gene id: 469383:CWOE_RS26715
uniprot id: D3FFD6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

469383:CWOE RS12380
gene id: 469383:CWOE_RS12380
uniprot id: D3F7P3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

469383:CWOE RS25040
gene id: 469383:CWOE_RS25040
uniprot id: D3FCA6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS29080
gene id: 469383:CWOE_RS29080
uniprot id: D3F2R1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

469383:CWOE RS19125
gene id: 469383:CWOE_RS19125
uniprot id: D3F2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS18415
gene id: 469383:CWOE_RS18415
uniprot id: D3F1D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

469383:CWOE RS14875
gene id: 469383:CWOE_RS14875
uniprot id: D3FBY6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00010
gene id: 469383:CWOE_RS00010
uniprot id: D3EYP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

469383:CWOE RS13520
gene id: 469383:CWOE_RS13520
uniprot id: D3F9R8
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

469383:CWOE RS13660
gene id: 469383:CWOE_RS13660
uniprot id: D3F9U6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS05355
gene id: 469383:CWOE_RS05355
uniprot id: D3FCM9
names: Similarity
messages: Belongs to the QNG1 protein family.

469383:CWOE RS14265
gene id: 469383:CWOE_RS14265
uniprot id: D3FAW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

469383:CWOE RS13110
gene id: 469383:CWOE_RS13110
uniprot id: D3F8T4
names: Similarity
messages: Belongs to the YciI family.

469383:CWOE RS31560
gene id: 469383:CWOE_RS31560
uniprot id: D3FFE1
names: Similarity
messages: Belongs to the UPF0502 family.

469383:CWOE RS19075
gene id: 469383:CWOE_RS19075
uniprot id: D3F2F9
names: Similarity
messages: Belongs to the TPP enzyme family.

469383:CWOE RS05835
gene id: 469383:CWOE_RS05835
uniprot id: D3FDM4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

469383:CWOE RS10320
gene id: 469383:CWOE_RS10320
uniprot id: D3F4C5
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

469383:CWOE RS13405
gene id: 469383:CWOE_RS13405
uniprot id: D3F9P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

469383:CWOE RS18545
gene id: 469383:CWOE_RS18545
uniprot id: D3F1F9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

469383:CWOE RS17395
gene id: 469383:CWOE_RS17395
uniprot id: D3EZD5
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

469383:CWOE RS07990
gene id: 469383:CWOE_RS07990
uniprot id: D3F052
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

469383:CWOE RS31025
gene id: 469383:CWOE_RS31025
uniprot id: D3F1E2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

469383:CWOE RS34000
gene id: 469383:CWOE_RS34000
uniprot id: D3F1M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS30200
gene id: 469383:CWOE_RS30200
uniprot id: D3FBI5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

469383:CWOE RS18565
gene id: 469383:CWOE_RS18565
uniprot id: D3F1G3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS09530
gene id: 469383:CWOE_RS09530
uniprot id: D3F359
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS16020
gene id: 469383:CWOE_RS16020
uniprot id: D3FE11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

469383:CWOE RS06730
gene id: 469383:CWOE_RS06730
uniprot id: D3FEU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

469383:CWOE RS05770
gene id: 469383:CWOE_RS05770
uniprot id: D3FDL1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

469383:CWOE RS11990
gene id: 469383:CWOE_RS11990
uniprot id: D3F7G7
names: Similarity
messages: Belongs to the sulfatase family.

469383:CWOE RS14515
gene id: 469383:CWOE_RS14515
uniprot id: D3FBR4
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS10520
gene id: 469383:CWOE_RS10520
uniprot id: D3F4G3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS03130
gene id: 469383:CWOE_RS03130
uniprot id: D3F994
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

469383:CWOE RS14230
gene id: 469383:CWOE_RS14230
uniprot id: D3FAV8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

469383:CWOE RS12700
gene id: 469383:CWOE_RS12700
uniprot id: D3F8K5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

469383:CWOE RS23080
gene id: 469383:CWOE_RS23080
uniprot id: D3F913
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

469383:CWOE RS00340
gene id: 469383:CWOE_RS00340
uniprot id: D3F420
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

469383:CWOE RS14700
gene id: 469383:CWOE_RS14700
uniprot id: D3FBV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS27485
gene id: 469383:CWOE_RS27485
uniprot id: D3EZN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

469383:CWOE RS08535
gene id: 469383:CWOE_RS08535
uniprot id: D3F161
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS06790
gene id: 469383:CWOE_RS06790
uniprot id: D3FEW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

469383:CWOE RS07285
gene id: 469383:CWOE_RS07285
uniprot id: D3EZ10
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

469383:CWOE RS04960
gene id: 469383:CWOE_RS04960
uniprot id: D3FCF2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS18750
gene id: 469383:CWOE_RS18750
uniprot id: D3F1J9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

469383:CWOE RS04095
gene id: 469383:CWOE_RS04095
uniprot id: D3FAI5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

469383:CWOE RS10790
gene id: 469383:CWOE_RS10790
uniprot id: D3F5C3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

469383:CWOE RS14800
gene id: 469383:CWOE_RS14800
uniprot id: D3FBX1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

469383:CWOE RS17470
gene id: 469383:CWOE_RS17470
uniprot id: D3EZF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

469383:CWOE RS12185
gene id: 469383:CWOE_RS12185
uniprot id: D3F7K6
names: Similarity
messages: Belongs to the NodU/CmcH family.

469383:CWOE RS02285
gene id: 469383:CWOE_RS02285
uniprot id: D3F7C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS22075
gene id: 469383:CWOE_RS22075
uniprot id: D3F7R9
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

469383:CWOE RS18800
gene id: 469383:CWOE_RS18800
uniprot id: D3F1K9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

469383:CWOE RS27750
gene id: 469383:CWOE_RS27750
uniprot id: D3F0J6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS05870
gene id: 469383:CWOE_RS05870
uniprot id: D3FDN1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

469383:CWOE RS26555
gene id: 469383:CWOE_RS26555
uniprot id: D3FFA4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

469383:CWOE RS18070
gene id: 469383:CWOE_RS18070
uniprot id: D3F0H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

469383:CWOE RS25340
gene id: 469383:CWOE_RS25340
uniprot id: D3FD69
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS02850
gene id: 469383:CWOE_RS02850
uniprot id: D3F8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS18335
gene id: 469383:CWOE_RS18335
uniprot id: D3F1B7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

469383:CWOE RS25200
gene id: 469383:CWOE_RS25200
uniprot id: D3FD41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS09075
gene id: 469383:CWOE_RS09075
uniprot id: D3F270
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS28040
gene id: 469383:CWOE_RS28040
uniprot id: D3F0Q3
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

469383:CWOE RS15090
gene id: 469383:CWOE_RS15090
uniprot id: D3FCT1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS16460
gene id: 469383:CWOE_RS16460
uniprot id: D3FEZ8
names: Similarity
messages: Belongs to the HIBADH-related family.

469383:CWOE RS12375
gene id: 469383:CWOE_RS12375
uniprot id: D3F7P2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

469383:CWOE RS25885
gene id: 469383:CWOE_RS25885
uniprot id: D3FE77
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS12225
gene id: 469383:CWOE_RS12225
uniprot id: D3F7L4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

469383:CWOE RS00765
gene id: 469383:CWOE_RS00765
uniprot id: D3F509
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

469383:CWOE RS18595
gene id: 469383:CWOE_RS18595
uniprot id: D3F1G9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS15150
gene id: 469383:CWOE_RS15150
uniprot id: D3FCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

469383:CWOE RS25135
gene id: 469383:CWOE_RS25135
uniprot id: D3FCC5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

469383:CWOE RS24680
gene id: 469383:CWOE_RS24680
uniprot id: D3FC33
names: Similarity
messages: Belongs to the universal stress protein A family.

469383:CWOE RS15155
gene id: 469383:CWOE_RS15155
uniprot id: D3FCU4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS12315
gene id: 469383:CWOE_RS12315
uniprot id: D3F7N0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS13890
gene id: 469383:CWOE_RS13890
uniprot id: D3FAP1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

469383:CWOE RS15465
gene id: 469383:CWOE_RS15465
uniprot id: D3FD06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS30900
gene id: 469383:CWOE_RS30900
uniprot id: D3EZ73
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

469383:CWOE RS00345
gene id: 469383:CWOE_RS00345
uniprot id: D3F421
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

469383:CWOE RS23370
gene id: 469383:CWOE_RS23370
uniprot id: D3F9X1
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

469383:CWOE RS00525
gene id: 469383:CWOE_RS00525
uniprot id: D3F4W1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

469383:CWOE RS08425
gene id: 469383:CWOE_RS08425
uniprot id: D3F140
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

469383:CWOE RS19415
gene id: 469383:CWOE_RS19415
uniprot id: D3F2M7
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

469383:CWOE RS16285
gene id: 469383:CWOE_RS16285
uniprot id: D3FE63
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS27135
gene id: 469383:CWOE_RS27135
uniprot id: D3EZH1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS14375
gene id: 469383:CWOE_RS14375
uniprot id: D3FAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

469383:CWOE RS02815
gene id: 469383:CWOE_RS02815
uniprot id: D3F8C6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS25155
gene id: 469383:CWOE_RS25155
uniprot id: D3FCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS02645
gene id: 469383:CWOE_RS02645
uniprot id: D3F893
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS25195
gene id: 469383:CWOE_RS25195
uniprot id: D3FCD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS09955
gene id: 469383:CWOE_RS09955
uniprot id: D3F452
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS17895
gene id: 469383:CWOE_RS17895
uniprot id: D3F0D6
names: Similarity
messages: Belongs to the isochorismate synthase family.

469383:CWOE RS10760
gene id: 469383:CWOE_RS10760
uniprot id: D3F5B6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469383:CWOE RS12520
gene id: 469383:CWOE_RS12520
uniprot id: D3F8G9
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Belongs to the HIBADH-related family.

469383:CWOE RS19965
gene id: 469383:CWOE_RS19965
uniprot id: D3F3N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS05230
gene id: 469383:CWOE_RS05230
uniprot id: D3FCK5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

469383:CWOE RS26305
gene id: 469383:CWOE_RS26305
uniprot id: D3FEF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

469383:CWOE RS27990
gene id: 469383:CWOE_RS27990
uniprot id: D3F0P4
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00580
gene id: 469383:CWOE_RS00580
uniprot id: D3F4X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS14235
gene id: 469383:CWOE_RS14235
uniprot id: D3FAV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

469383:CWOE RS05785
gene id: 469383:CWOE_RS05785
uniprot id: D3FDL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

469383:CWOE RS12270
gene id: 469383:CWOE_RS12270
uniprot id: D3F7M3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS03120
gene id: 469383:CWOE_RS03120
uniprot id: D3F992
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS20170
gene id: 469383:CWOE_RS20170
uniprot id: D3F4I4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

469383:CWOE RS08345
gene id: 469383:CWOE_RS08345
uniprot id: D3F124
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

469383:CWOE RS27790
gene id: 469383:CWOE_RS27790
uniprot id: D3F0K4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

469383:CWOE RS06830
gene id: 469383:CWOE_RS06830
uniprot id: D3EYR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

469383:CWOE RS11410
gene id: 469383:CWOE_RS11410
uniprot id: D3F6E8
names: Similarity
messages: Belongs to the CdaR family.

469383:CWOE RS19150
gene id: 469383:CWOE_RS19150
uniprot id: D3F2H4
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS09395
gene id: 469383:CWOE_RS09395
uniprot id: D3F331
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

469383:CWOE RS00335
gene id: 469383:CWOE_RS00335
uniprot id: D3F419
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

469383:CWOE RS28815
gene id: 469383:CWOE_RS28815
uniprot id: D3F1V8
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

469383:CWOE RS03305
gene id: 469383:CWOE_RS03305
uniprot id: D3F9D0
names: Cofactor
messages: Binds 1 FAD per subunit.

469383:CWOE RS00180
gene id: 469383:CWOE_RS00180
uniprot id: D3F3Y9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

469383:CWOE RS15965
gene id: 469383:CWOE_RS15965
uniprot id: D3FE00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

469383:CWOE RS13375
gene id: 469383:CWOE_RS13375
uniprot id: D3F9P0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS20135
gene id: 469383:CWOE_RS20135
uniprot id: D3F4H6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS08435
gene id: 469383:CWOE_RS08435
uniprot id: D3F142
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

469383:CWOE RS25560
gene id: 469383:CWOE_RS25560
uniprot id: D3FDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS22765
gene id: 469383:CWOE_RS22765
uniprot id: D3F8V1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

469383:CWOE RS25625
gene id: 469383:CWOE_RS25625
uniprot id: D3FDC5
names: Similarity
messages: Belongs to the creatininase superfamily.

469383:CWOE RS08460
gene id: 469383:CWOE_RS08460
uniprot id: D3F146
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

469383:CWOE RS01525
gene id: 469383:CWOE_RS01525
uniprot id: D3F666
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00600
gene id: 469383:CWOE_RS00600
uniprot id: D3F4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

469383:CWOE RS18475
gene id: 469383:CWOE_RS18475
uniprot id: D3F1E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

469383:CWOE RS01750
gene id: 469383:CWOE_RS01750
uniprot id: D3F713
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS03675
gene id: 469383:CWOE_RS03675
uniprot id: D3FAA0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS11875
gene id: 469383:CWOE_RS11875
uniprot id: D3F7E5
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

469383:CWOE RS15350
gene id: 469383:CWOE_RS15350
uniprot id: D3FCY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

469383:CWOE RS25495
gene id: 469383:CWOE_RS25495
uniprot id: D3FD99
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

469383:CWOE RS04040
gene id: 469383:CWOE_RS04040
uniprot id: D3FAH4
names: Similarity
messages: Belongs to the peptidase M20A family.

469383:CWOE RS00135
gene id: 469383:CWOE_RS00135
uniprot id: D3F3X9
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

469383:CWOE RS16195
gene id: 469383:CWOE_RS16195
uniprot id: D3FE46
names: Similarity
messages: Belongs to the CinA family.

469383:CWOE RS29755
gene id: 469383:CWOE_RS29755
uniprot id: D3F3V0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

469383:CWOE RS13115
gene id: 469383:CWOE_RS13115
uniprot id: D3F8T5
names: Similarity
messages: Belongs to the CdaR family.

469383:CWOE RS21850
gene id: 469383:CWOE_RS21850
uniprot id: D3F6X1
names: Subcellular Location Annotation
messages: Mitochondrion

469383:CWOE RS20755
gene id: 469383:CWOE_RS20755
uniprot id: D3F4U5
names: Similarity
messages: Belongs to the peptidase M29 family.

469383:CWOE RS18630
gene id: 469383:CWOE_RS18630
uniprot id: D3F1H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

469383:CWOE RS06245
gene id: 469383:CWOE_RS06245
uniprot id: D3FEK1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS15270
gene id: 469383:CWOE_RS15270
uniprot id: D3FCW7
names: Similarity
messages: Belongs to the peptidase M24B family.

469383:CWOE RS24590
gene id: 469383:CWOE_RS24590
uniprot id: D3FC15
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS16080
gene id: 469383:CWOE_RS16080
uniprot id: D3FE23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

469383:CWOE RS12350
gene id: 469383:CWOE_RS12350
uniprot id: D3F7N7
names: Similarity
messages: Belongs to the AHA1 family.

469383:CWOE RS09925
gene id: 469383:CWOE_RS09925
uniprot id: D3F3D7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS10950
gene id: 469383:CWOE_RS10950
uniprot id: D3F5F4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469383:CWOE RS16920
gene id: 469383:CWOE_RS16920
uniprot id: D3EZ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anti-sigma-factor antagonist family.
messages: Membrane

469383:CWOE RS29330
gene id: 469383:CWOE_RS29330
uniprot id: D3F2W0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS21005
gene id: 469383:CWOE_RS21005
uniprot id: D3F5Q2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS11405
gene id: 469383:CWOE_RS11405
uniprot id: D3F6E7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Heterodimer of an alpha and a beta chain.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS04905
gene id: 469383:CWOE_RS04905
uniprot id: D3FCE1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS11195
gene id: 469383:CWOE_RS11195
uniprot id: D3F5K3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS23145
gene id: 469383:CWOE_RS23145
uniprot id: D3F926
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS03615
gene id: 469383:CWOE_RS03615
uniprot id: D3F9J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

469383:CWOE RS00240
gene id: 469383:CWOE_RS00240
uniprot id: D3F401
names: Similarity
messages: Belongs to the FlgD family.

469383:CWOE RS04400
gene id: 469383:CWOE_RS04400
uniprot id: D3FBE4
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS15820
gene id: 469383:CWOE_RS15820
uniprot id: D3FDX2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

469383:CWOE RS14675
gene id: 469383:CWOE_RS14675
uniprot id: D3FBU6
names: Similarity
messages: Belongs to the DapA family.

469383:CWOE RS28180
gene id: 469383:CWOE_RS28180
uniprot id: D3F0T1
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

469383:CWOE RS18125
gene id: 469383:CWOE_RS18125
uniprot id: D3F0I1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS31020
gene id: 469383:CWOE_RS31020
uniprot id: D3F1D4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

469383:CWOE RS30400
gene id: 469383:CWOE_RS30400
uniprot id: D3F002
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

469383:CWOE RS26985
gene id: 469383:CWOE_RS26985
uniprot id: D3FFI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

469383:CWOE RS07720
gene id: 469383:CWOE_RS07720
uniprot id: D3EZZ7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

469383:CWOE RS06040
gene id: 469383:CWOE_RS06040
uniprot id: D3FDR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS00310
gene id: 469383:CWOE_RS00310
uniprot id: D3F415
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

469383:CWOE RS02985
gene id: 469383:CWOE_RS02985
uniprot id: D3F8G0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS17860
gene id: 469383:CWOE_RS17860
uniprot id: D3F0D0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS18035
gene id: 469383:CWOE_RS18035
uniprot id: D3F0G2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

469383:CWOE RS15780
gene id: 469383:CWOE_RS15780
uniprot id: D3FDW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

469383:CWOE RS18525
gene id: 469383:CWOE_RS18525
uniprot id: D3F1F5
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

469383:CWOE RS13225
gene id: 469383:CWOE_RS13225
uniprot id: D3F9L0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

469383:CWOE RS17870
gene id: 469383:CWOE_RS17870
uniprot id: D3F0D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

469383:CWOE RS21350
gene id: 469383:CWOE_RS21350
uniprot id: D3F5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS04590
gene id: 469383:CWOE_RS04590
uniprot id: D3FBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS24510
gene id: 469383:CWOE_RS24510
uniprot id: D3FBA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS01020
gene id: 469383:CWOE_RS01020
uniprot id: D3F562
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS24380
gene id: 469383:CWOE_RS24380
uniprot id: D3FB76
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS18795
gene id: 469383:CWOE_RS18795
uniprot id: D3F1K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

469383:CWOE RS20860
gene id: 469383:CWOE_RS20860
uniprot id: D3F5M4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

469383:CWOE RS13775
gene id: 469383:CWOE_RS13775
uniprot id: D3FAL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS19185
gene id: 469383:CWOE_RS19185
uniprot id: D3F2I1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

469383:CWOE RS17945
gene id: 469383:CWOE_RS17945
uniprot id: D3F0E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

469383:CWOE RS08940
gene id: 469383:CWOE_RS08940
uniprot id: D3F242
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

469383:CWOE RS21655
gene id: 469383:CWOE_RS21655
uniprot id: D3F6T2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

469383:CWOE RS21075
gene id: 469383:CWOE_RS21075
uniprot id: D3F5R6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

469383:CWOE RS29000
gene id: 469383:CWOE_RS29000
uniprot id: D3F2P5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469383:CWOE RS27995
gene id: 469383:CWOE_RS27995
uniprot id: D3F0P5
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS23765
gene id: 469383:CWOE_RS23765
uniprot id: D3FA48
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS27080
gene id: 469383:CWOE_RS27080
uniprot id: D3FFK5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

469383:CWOE RS16670
gene id: 469383:CWOE_RS16670
uniprot id: D3FF39
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

469383:CWOE RS05875
gene id: 469383:CWOE_RS05875
uniprot id: D3FDN2
names: Similarity
messages: Belongs to the Dps family.

469383:CWOE RS23925
gene id: 469383:CWOE_RS23925
uniprot id: D3FA80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

469383:CWOE RS06825
gene id: 469383:CWOE_RS06825
uniprot id: D3EYR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

469383:CWOE RS06045
gene id: 469383:CWOE_RS06045
uniprot id: D3FDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS03195
gene id: 469383:CWOE_RS03195
uniprot id: D3F9A7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

469383:CWOE RS15380
gene id: 469383:CWOE_RS15380
uniprot id: D3FCY9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

469383:CWOE RS08200
gene id: 469383:CWOE_RS08200
uniprot id: D3F0Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS26525
gene id: 469383:CWOE_RS26525
uniprot id: D3FF98
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

469383:CWOE RS06860
gene id: 469383:CWOE_RS06860
uniprot id: D3EYS5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

469383:CWOE RS15580
gene id: 469383:CWOE_RS15580
uniprot id: D3FD28
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS05280
gene id: 469383:CWOE_RS05280
uniprot id: D3FCL5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS28765
gene id: 469383:CWOE_RS28765
uniprot id: D3F1U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

469383:CWOE RS02680
gene id: 469383:CWOE_RS02680
uniprot id: D3F8A0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS13470
gene id: 469383:CWOE_RS13470
uniprot id: D3F9Q8
names: Similarity
messages: Belongs to the peptidase S45 family.

469383:CWOE RS10555
gene id: 469383:CWOE_RS10555
uniprot id: D3F4H0
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS18425
gene id: 469383:CWOE_RS18425
uniprot id: D3F1D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

469383:CWOE RS29910
gene id: 469383:CWOE_RS29910
uniprot id: D3F3Z0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

469383:CWOE RS04990
gene id: 469383:CWOE_RS04990
uniprot id: D3FCF8
names: Similarity
messages: Belongs to the peptidase S33 family.

469383:CWOE RS29395
gene id: 469383:CWOE_RS29395
uniprot id: D3F2X3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

469383:CWOE RS24665
gene id: 469383:CWOE_RS24665
uniprot id: D3FC30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

469383:CWOE RS17995
gene id: 469383:CWOE_RS17995
uniprot id: D3F0F5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

469383:CWOE RS16260
gene id: 469383:CWOE_RS16260
uniprot id: D3FE58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS19100
gene id: 469383:CWOE_RS19100
uniprot id: D3F2G4
names: Subcellular Location Annotation
messages: Periplasm

469383:CWOE RS25160
gene id: 469383:CWOE_RS25160
uniprot id: D3FCD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS17020
gene id: 469383:CWOE_RS17020
uniprot id: D3EZ61
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

469383:CWOE RS08835
gene id: 469383:CWOE_RS08835
uniprot id: D3F220
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

469383:CWOE RS10480
gene id: 469383:CWOE_RS10480
uniprot id: D3F4F5
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

469383:CWOE RS23015
gene id: 469383:CWOE_RS23015
uniprot id: D3F900
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

469383:CWOE RS16615
gene id: 469383:CWOE_RS16615
uniprot id: D3FF29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS01570
gene id: 469383:CWOE_RS01570
uniprot id: D3F675
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS20125
gene id: 469383:CWOE_RS20125
uniprot id: D3F3R6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS02745
gene id: 469383:CWOE_RS02745
uniprot id: D3F8B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

469383:CWOE RS29815
gene id: 469383:CWOE_RS29815
uniprot id: D3F3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

469383:CWOE RS27840
gene id: 469383:CWOE_RS27840
uniprot id: D3F0L4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

469383:CWOE RS01125
gene id: 469383:CWOE_RS01125
uniprot id: D3F5Y7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS25070
gene id: 469383:CWOE_RS25070
uniprot id: D3FCB2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

469383:CWOE RS16070
gene id: 469383:CWOE_RS16070
uniprot id: D3FE21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

469383:CWOE RS20390
gene id: 469383:CWOE_RS20390
uniprot id: D3F4M2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469383:CWOE RS07835
gene id: 469383:CWOE_RS07835
uniprot id: D3F020
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS16245
gene id: 469383:CWOE_RS16245
uniprot id: D3FE55
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS12280
gene id: 469383:CWOE_RS12280
uniprot id: D3F7M5
names: Similarity
messages: Belongs to the YciI family.

469383:CWOE RS15890
gene id: 469383:CWOE_RS15890
uniprot id: D3FDY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

469383:CWOE RS06070
gene id: 469383:CWOE_RS06070
uniprot id: D3FDR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS02435
gene id: 469383:CWOE_RS02435
uniprot id: D3F851
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

469383:CWOE RS02205
gene id: 469383:CWOE_RS02205
uniprot id: D3F7A6
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

469383:CWOE RS01060
gene id: 469383:CWOE_RS01060
uniprot id: D3F570
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

469383:CWOE RS16740
gene id: 469383:CWOE_RS16740
uniprot id: D3FF53
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

469383:CWOE RS02530
gene id: 469383:CWOE_RS02530
uniprot id: D3F870
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

469383:CWOE RS05750
gene id: 469383:CWOE_RS05750
uniprot id: D3FDK7
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

469383:CWOE RS04305
gene id: 469383:CWOE_RS04305
uniprot id: D3FBC5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS08560
gene id: 469383:CWOE_RS08560
uniprot id: D3F166
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

469383:CWOE RS13770
gene id: 469383:CWOE_RS13770
uniprot id: D3FAL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS16005
gene id: 469383:CWOE_RS16005
uniprot id: D3FE08
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

469383:CWOE RS27870
gene id: 469383:CWOE_RS27870
uniprot id: D3F0M0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS12970
gene id: 469383:CWOE_RS12970
uniprot id: D3F8Q6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS23320
gene id: 469383:CWOE_RS23320
uniprot id: D3F961
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469383:CWOE RS27780
gene id: 469383:CWOE_RS27780
uniprot id: D3F0K2
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

469383:CWOE RS18645
gene id: 469383:CWOE_RS18645
uniprot id: D3F1H9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

469383:CWOE RS18665
gene id: 469383:CWOE_RS18665
uniprot id: D3F1I3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

469383:CWOE RS17730
gene id: 469383:CWOE_RS17730
uniprot id: D3F0A4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

469383:CWOE RS30910
gene id: 469383:CWOE_RS30910
uniprot id: D3EZB0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

469383:CWOE RS07845
gene id: 469383:CWOE_RS07845
uniprot id: D3F023
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

469383:CWOE RS02155
gene id: 469383:CWOE_RS02155
uniprot id: D3F796
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS09465
gene id: 469383:CWOE_RS09465
uniprot id: D3F344
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469383:CWOE RS13190
gene id: 469383:CWOE_RS13190
uniprot id: D3F9K2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

469383:CWOE RS28295
gene id: 469383:CWOE_RS28295
uniprot id: D3F0V3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS31295
gene id: 469383:CWOE_RS31295
uniprot id: D3F915
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS08385
gene id: 469383:CWOE_RS08385
uniprot id: D3F132
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS06545
gene id: 469383:CWOE_RS06545
uniprot id: D3FER1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

469383:CWOE RS24205
gene id: 469383:CWOE_RS24205
uniprot id: D3FB40
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

469383:CWOE RS17930
gene id: 469383:CWOE_RS17930
uniprot id: D3F0E3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

469383:CWOE RS26560
gene id: 469383:CWOE_RS26560
uniprot id: D3FFA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

469383:CWOE RS13235
gene id: 469383:CWOE_RS13235
uniprot id: D3F9L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

469383:CWOE RS29695
gene id: 469383:CWOE_RS29695
uniprot id: D3F3T8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

469383:CWOE RS24215
gene id: 469383:CWOE_RS24215
uniprot id: D3FB42
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

469383:CWOE RS12000
gene id: 469383:CWOE_RS12000
uniprot id: D3F7G9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

469383:CWOE RS25110
gene id: 469383:CWOE_RS25110
uniprot id: D3FCC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

469383:CWOE RS29155
gene id: 469383:CWOE_RS29155
uniprot id: D3F2S6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS06680
gene id: 469383:CWOE_RS06680
uniprot id: D3FET8
names: Similarity
messages: Belongs to the CdaR family.

469383:CWOE RS09165
gene id: 469383:CWOE_RS09165
uniprot id: D3F288
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

469383:CWOE RS29285
gene id: 469383:CWOE_RS29285
uniprot id: D3F2V2
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

469383:CWOE RS11470
gene id: 469383:CWOE_RS11470
uniprot id: D3F6G0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS13305
gene id: 469383:CWOE_RS13305
uniprot id: D3F9M6
names: Similarity
messages: Belongs to the arginase family.

469383:CWOE RS13990
gene id: 469383:CWOE_RS13990
uniprot id: D3FAR1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

469383:CWOE RS17515
gene id: 469383:CWOE_RS17515
uniprot id: D3EZF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

469383:CWOE RS26590
gene id: 469383:CWOE_RS26590
uniprot id: D3FFB1
names: Similarity
messages: Belongs to the asparagine synthetase family.

469383:CWOE RS21595
gene id: 469383:CWOE_RS21595
uniprot id: D3F6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS06270
gene id: 469383:CWOE_RS06270
uniprot id: D3FEK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS08070
gene id: 469383:CWOE_RS08070
uniprot id: D3F0W9
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

469383:CWOE RS28525
gene id: 469383:CWOE_RS28525
uniprot id: D3F1Q2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS23820
gene id: 469383:CWOE_RS23820
uniprot id: D3FA59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS16165
gene id: 469383:CWOE_RS16165
uniprot id: D3FE40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

469383:CWOE RS18390
gene id: 469383:CWOE_RS18390
uniprot id: D3F1C8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

469383:CWOE RS01410
gene id: 469383:CWOE_RS01410
uniprot id: D3F643
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS17450
gene id: 469383:CWOE_RS17450
uniprot id: D3EZE6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

469383:CWOE RS08375
gene id: 469383:CWOE_RS08375
uniprot id: D3F130
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

469383:CWOE RS06765
gene id: 469383:CWOE_RS06765
uniprot id: D3FEV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

469383:CWOE RS11625
gene id: 469383:CWOE_RS11625
uniprot id: D3F6J0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469383:CWOE RS26995
gene id: 469383:CWOE_RS26995
uniprot id: D3FFI8
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS27085
gene id: 469383:CWOE_RS27085
uniprot id: D3EZG1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

469383:CWOE RS09150
gene id: 469383:CWOE_RS09150
uniprot id: D3F285
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

469383:CWOE RS29520
gene id: 469383:CWOE_RS29520
uniprot id: D3F2Z9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

469383:CWOE RS07080
gene id: 469383:CWOE_RS07080
uniprot id: D3EYW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

469383:CWOE RS13325
gene id: 469383:CWOE_RS13325
uniprot id: D3F9N0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

469383:CWOE RS07630
gene id: 469383:CWOE_RS07630
uniprot id: D3EZX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

469383:CWOE RS02345
gene id: 469383:CWOE_RS02345
uniprot id: D3F7D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

469383:CWOE RS04320
gene id: 469383:CWOE_RS04320
uniprot id: D3FBC8
names: Similarity
messages: Belongs to the AHA1 family.

469383:CWOE RS04950
gene id: 469383:CWOE_RS04950
uniprot id: D3FCF0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

469383:CWOE RS08370
gene id: 469383:CWOE_RS08370
uniprot id: D3F129
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS08410
gene id: 469383:CWOE_RS08410
uniprot id: D3F137
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

469383:CWOE RS16840
gene id: 469383:CWOE_RS16840
uniprot id: D3FF73
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

469383:CWOE RS27505
gene id: 469383:CWOE_RS27505
uniprot id: D3EZP2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS04705
gene id: 469383:CWOE_RS04705
uniprot id: D3FBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

469383:CWOE RS10525
gene id: 469383:CWOE_RS10525
uniprot id: D3F4G4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS23285
gene id: 469383:CWOE_RS23285
uniprot id: D3F954
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

469383:CWOE RS18080
gene id: 469383:CWOE_RS18080
uniprot id: D3F0H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

469383:CWOE RS26145
gene id: 469383:CWOE_RS26145
uniprot id: D3FEC4
names: Similarity
messages: Belongs to the TPP enzyme family.

469383:CWOE RS04750
gene id: 469383:CWOE_RS04750
uniprot id: D3FBL4
names: Similarity
messages: Belongs to the cytochrome P450 family.

469383:CWOE RS17300
gene id: 469383:CWOE_RS17300
uniprot id: D3EZB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

469383:CWOE RS26400
gene id: 469383:CWOE_RS26400
uniprot id: D3FEH4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

469383:CWOE RS13915
gene id: 469383:CWOE_RS13915
uniprot id: D3FAP6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS25085
gene id: 469383:CWOE_RS25085
uniprot id: D3FCB5
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

469383:CWOE RS13120
gene id: 469383:CWOE_RS13120
uniprot id: D3F8T6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS09340
gene id: 469383:CWOE_RS09340
uniprot id: D3F320
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

469383:CWOE RS02400
gene id: 469383:CWOE_RS02400
uniprot id: D3F844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

469383:CWOE RS23545
gene id: 469383:CWOE_RS23545
uniprot id: D3FA06
names: Similarity
messages: Belongs to the FBPase class 2 family.

469383:CWOE RS04585
gene id: 469383:CWOE_RS04585
uniprot id: D3FBI1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469383:CWOE RS23890
gene id: 469383:CWOE_RS23890
uniprot id: D3FA73
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS31415
gene id: 469383:CWOE_RS31415
uniprot id: D3FCA8
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS09160
gene id: 469383:CWOE_RS09160
uniprot id: D3F287
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

469383:CWOE RS14400
gene id: 469383:CWOE_RS14400
uniprot id: D3FAZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

469383:CWOE RS09625
gene id: 469383:CWOE_RS09625
uniprot id: D3F378
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS09240
gene id: 469383:CWOE_RS09240
uniprot id: D3F2A4
names: Similarity
messages: Belongs to the peptidase S45 family.

469383:CWOE RS06035
gene id: 469383:CWOE_RS06035
uniprot id: D3FDR0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS09775
gene id: 469383:CWOE_RS09775
uniprot id: D3F3A8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS01890
gene id: 469383:CWOE_RS01890
uniprot id: D3F741
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS12655
gene id: 469383:CWOE_RS12655
uniprot id: D3F8J6
names: Similarity
messages: Belongs to the HypD family.

469383:CWOE RS14305
gene id: 469383:CWOE_RS14305
uniprot id: D3FAX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

469383:CWOE RS29170
gene id: 469383:CWOE_RS29170
uniprot id: D3F2S9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

469383:CWOE RS28920
gene id: 469383:CWOE_RS28920
uniprot id: D3F1X9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS07075
gene id: 469383:CWOE_RS07075
uniprot id: D3EYW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

469383:CWOE RS06695
gene id: 469383:CWOE_RS06695
uniprot id: D3FEU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

469383:CWOE RS15265
gene id: 469383:CWOE_RS15265
uniprot id: D3FCW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

469383:CWOE RS26870
gene id: 469383:CWOE_RS26870
uniprot id: D3FFG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

469383:CWOE RS30580
gene id: 469383:CWOE_RS30580
uniprot id: D3F6D8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

469383:CWOE RS29225
gene id: 469383:CWOE_RS29225
uniprot id: D3F2U0
names: Similarity
messages: Belongs to the arginase family.

469383:CWOE RS15870
gene id: 469383:CWOE_RS15870
uniprot id: D3FDY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

469383:CWOE RS17075
gene id: 469383:CWOE_RS17075
uniprot id: D3EZ71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

469383:CWOE RS00960
gene id: 469383:CWOE_RS00960
uniprot id: D3F550
names: Similarity
messages: Belongs to the asparaginase 1 family.

469383:CWOE RS29340
gene id: 469383:CWOE_RS29340
uniprot id: D3F2W2
names: Similarity
messages: Belongs to the AHA1 family.

469383:CWOE RS06020
gene id: 469383:CWOE_RS06020
uniprot id: D3FDQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469383:CWOE RS08955
gene id: 469383:CWOE_RS08955
uniprot id: D3F245
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

469383:CWOE RS29500
gene id: 469383:CWOE_RS29500
uniprot id: D3F2Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

469383:CWOE RS16140
gene id: 469383:CWOE_RS16140
uniprot id: D3FE35
names: Similarity
messages: Belongs to the peptidase M16 family.

469383:CWOE RS04215
gene id: 469383:CWOE_RS04215
uniprot id: D3FAK7
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

469383:CWOE RS05380
gene id: 469383:CWOE_RS05380
uniprot id: D3FCN4
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

469383:CWOE RS23490
gene id: 469383:CWOE_RS23490
uniprot id: D3F9Z5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

469383:CWOE RS02760
gene id: 469383:CWOE_RS02760
uniprot id: D3F8B6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS14605
gene id: 469383:CWOE_RS14605
uniprot id: D3FBT2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

469383:CWOE RS16905
gene id: 469383:CWOE_RS16905
uniprot id: D3EZ38
names: Similarity
messages: Belongs to the AHA1 family.

469383:CWOE RS25100
gene id: 469383:CWOE_RS25100
uniprot id: D3FCB8
names: Subcellular Location Annotation
messages: Cytoplasm

469383:CWOE RS11585
gene id: 469383:CWOE_RS11585
uniprot id: D3F6I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS30315
gene id: 469383:CWOE_RS30315
uniprot id: D3FEP2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS13740
gene id: 469383:CWOE_RS13740
uniprot id: D3F9W2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

469383:CWOE RS30285
gene id: 469383:CWOE_RS30285
uniprot id: D3FDM8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS19265
gene id: 469383:CWOE_RS19265
uniprot id: D3F2J7
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS28460
gene id: 469383:CWOE_RS28460
uniprot id: D3F1N9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS18620
gene id: 469383:CWOE_RS18620
uniprot id: D3F1H4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS19455
gene id: 469383:CWOE_RS19455
uniprot id: D3F2N5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS18075
gene id: 469383:CWOE_RS18075
uniprot id: D3F0H1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

469383:CWOE RS27810
gene id: 469383:CWOE_RS27810
uniprot id: D3F0K8
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS01555
gene id: 469383:CWOE_RS01555
uniprot id: D3F672
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS21040
gene id: 469383:CWOE_RS21040
uniprot id: D3F5Q9
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

469383:CWOE RS19085
gene id: 469383:CWOE_RS19085
uniprot id: D3F2G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS27170
gene id: 469383:CWOE_RS27170
uniprot id: D3EZH7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

469383:CWOE RS05745
gene id: 469383:CWOE_RS05745
uniprot id: D3FDK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

469383:CWOE RS02245
gene id: 469383:CWOE_RS02245
uniprot id: D3F7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

469383:CWOE RS22720
gene id: 469383:CWOE_RS22720
uniprot id: D3F8U2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

469383:CWOE RS07940
gene id: 469383:CWOE_RS07940
uniprot id: D3F042
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS04830
gene id: 469383:CWOE_RS04830
uniprot id: D3FBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS22080
gene id: 469383:CWOE_RS22080
uniprot id: D3F7S0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS20465
gene id: 469383:CWOE_RS20465
uniprot id: D3F4N7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

469383:CWOE RS20695
gene id: 469383:CWOE_RS20695
uniprot id: D3F4T3
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

469383:CWOE RS22625
gene id: 469383:CWOE_RS22625
uniprot id: D3F825
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

469383:CWOE RS17935
gene id: 469383:CWOE_RS17935
uniprot id: D3F0E4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

469383:CWOE RS18715
gene id: 469383:CWOE_RS18715
uniprot id: D3F1J3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

469383:CWOE RS16000
gene id: 469383:CWOE_RS16000
uniprot id: D3FE07
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS12275
gene id: 469383:CWOE_RS12275
uniprot id: D3F7M4
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS01195
gene id: 469383:CWOE_RS01195
uniprot id: D3F601
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS27300
gene id: 469383:CWOE_RS27300
uniprot id: D3EZK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

469383:CWOE RS08900
gene id: 469383:CWOE_RS08900
uniprot id: D3F233
names: Similarity
messages: Belongs to the PspA/IM30 family.

469383:CWOE RS29845
gene id: 469383:CWOE_RS29845
uniprot id: D3F3W7
names: Similarity
messages: Belongs to the ParB family.

469383:CWOE RS06715
gene id: 469383:CWOE_RS06715
uniprot id: D3FEU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

469383:CWOE RS18935
gene id: 469383:CWOE_RS18935
uniprot id: D3F2D2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS22825
gene id: 469383:CWOE_RS22825
uniprot id: D3F8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

469383:CWOE RS03065
gene id: 469383:CWOE_RS03065
uniprot id: D3F981
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS06880
gene id: 469383:CWOE_RS06880
uniprot id: D3EYS9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

469383:CWOE RS23520
gene id: 469383:CWOE_RS23520
uniprot id: D3FA01
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

469383:CWOE RS17925
gene id: 469383:CWOE_RS17925
uniprot id: D3F0E2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

469383:CWOE RS02295
gene id: 469383:CWOE_RS02295
uniprot id: D3F7C4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

469383:CWOE RS12965
gene id: 469383:CWOE_RS12965
uniprot id: D3F8Q5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS08185
gene id: 469383:CWOE_RS08185
uniprot id: D3F0Z2
names: Similarity
messages: Belongs to the P(II) protein family.

469383:CWOE RS17555
gene id: 469383:CWOE_RS17555
uniprot id: D3F072
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

469383:CWOE RS06650
gene id: 469383:CWOE_RS06650
uniprot id: D3FET2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

469383:CWOE RS24685
gene id: 469383:CWOE_RS24685
uniprot id: D3FC34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

469383:CWOE RS17845
gene id: 469383:CWOE_RS17845
uniprot id: D3F0C7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS08525
gene id: 469383:CWOE_RS08525
uniprot id: D3F159
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS01740
gene id: 469383:CWOE_RS01740
uniprot id: D3F6A9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS16205
gene id: 469383:CWOE_RS16205
uniprot id: D3FE48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

469383:CWOE RS25480
gene id: 469383:CWOE_RS25480
uniprot id: D3FD96
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

469383:CWOE RS17530
gene id: 469383:CWOE_RS17530
uniprot id: D3F067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

469383:CWOE RS12070
gene id: 469383:CWOE_RS12070
uniprot id: D3F7I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS02040
gene id: 469383:CWOE_RS02040
uniprot id: D3F772
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS18265
gene id: 469383:CWOE_RS18265
uniprot id: D3F1A2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS09535
gene id: 469383:CWOE_RS09535
uniprot id: D3F360
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

469383:CWOE RS27660
gene id: 469383:CWOE_RS27660
uniprot id: D3EZS3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

469383:CWOE RS10935
gene id: 469383:CWOE_RS10935
uniprot id: D3F5F1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

469383:CWOE RS22100
gene id: 469383:CWOE_RS22100
uniprot id: D3F7S4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

469383:CWOE RS28455
gene id: 469383:CWOE_RS28455
uniprot id: D3F1N8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS03610
gene id: 469383:CWOE_RS03610
uniprot id: D3F9I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

469383:CWOE RS14665
gene id: 469383:CWOE_RS14665
uniprot id: D3FBU4
names: Similarity
messages: Belongs to the creatininase superfamily.

469383:CWOE RS03545
gene id: 469383:CWOE_RS03545
uniprot id: D3F9H6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS29215
gene id: 469383:CWOE_RS29215
uniprot id: D3F2T8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

469383:CWOE RS14420
gene id: 469383:CWOE_RS14420
uniprot id: D3FBP5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

469383:CWOE RS27100
gene id: 469383:CWOE_RS27100
uniprot id: D3EZG4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

469383:CWOE RS24965
gene id: 469383:CWOE_RS24965
uniprot id: D3FC91
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

469383:CWOE RS18120
gene id: 469383:CWOE_RS18120
uniprot id: D3F0I0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS15140
gene id: 469383:CWOE_RS15140
uniprot id: D3FCU1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

469383:CWOE RS31070
gene id: 469383:CWOE_RS31070
uniprot id: D3F2E9
names: Similarity
messages: Belongs to the terpene synthase family.

469383:CWOE RS19835
gene id: 469383:CWOE_RS19835
uniprot id: D3F3L0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

469383:CWOE RS18540
gene id: 469383:CWOE_RS18540
uniprot id: D3F1F8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

469383:CWOE RS27240
gene id: 469383:CWOE_RS27240
uniprot id: D3EZJ0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

469383:CWOE RS27280
gene id: 469383:CWOE_RS27280
uniprot id: D3EZJ8
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

469383:CWOE RS14185
gene id: 469383:CWOE_RS14185
uniprot id: D3FAU9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

469383:CWOE RS18395
gene id: 469383:CWOE_RS18395
uniprot id: D3F1C9
names: Similarity
messages: Belongs to the UPF0102 family.

469383:CWOE RS14575
gene id: 469383:CWOE_RS14575
uniprot id: D3FBS5
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS17455
gene id: 469383:CWOE_RS17455
uniprot id: D3EZE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS33725
gene id: 469383:CWOE_RS33725
uniprot id: D3F2P6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS23360
gene id: 469383:CWOE_RS23360
uniprot id: D3F9W9
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

469383:CWOE RS10455
gene id: 469383:CWOE_RS10455
uniprot id: D3F4F0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

469383:CWOE RS02335
gene id: 469383:CWOE_RS02335
uniprot id: D3F7D2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS29685
gene id: 469383:CWOE_RS29685
uniprot id: D3F3T6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

469383:CWOE RS01260
gene id: 469383:CWOE_RS01260
uniprot id: D3F613
names: Similarity
messages: Belongs to the AHA1 family.

469383:CWOE RS31265
gene id: 469383:CWOE_RS31265
uniprot id: D3F835
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

469383:CWOE RS18355
gene id: 469383:CWOE_RS18355
uniprot id: D3F1C1
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

469383:CWOE RS24275
gene id: 469383:CWOE_RS24275
uniprot id: D3FB54
names: Caution
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS14840
gene id: 469383:CWOE_RS14840
uniprot id: D3FBX9
names: Similarity
messages: Belongs to the creatininase superfamily.

469383:CWOE RS11650
gene id: 469383:CWOE_RS11650
uniprot id: D3F6J5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS15255
gene id: 469383:CWOE_RS15255
uniprot id: D3FCW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

469383:CWOE RS04765
gene id: 469383:CWOE_RS04765
uniprot id: D3FBL7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

469383:CWOE RS16850
gene id: 469383:CWOE_RS16850
uniprot id: D3FF75
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

469383:CWOE RS14855
gene id: 469383:CWOE_RS14855
uniprot id: D3FBY2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

469383:CWOE RS25655
gene id: 469383:CWOE_RS25655
uniprot id: D3FDD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS08160
gene id: 469383:CWOE_RS08160
uniprot id: D3F0Y7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS08855
gene id: 469383:CWOE_RS08855
uniprot id: D3F224
names: Similarity
messages: Belongs to the XseB family.

469383:CWOE RS21930
gene id: 469383:CWOE_RS21930
uniprot id: D3F6Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS23995
gene id: 469383:CWOE_RS23995
uniprot id: D3FAZ7
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS26465
gene id: 469383:CWOE_RS26465
uniprot id: D3FF86
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

469383:CWOE RS28670
gene id: 469383:CWOE_RS28670
uniprot id: D3F1S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS00285
gene id: 469383:CWOE_RS00285
uniprot id: D3F410
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

469383:CWOE RS05780
gene id: 469383:CWOE_RS05780
uniprot id: D3FDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

469383:CWOE RS22470
gene id: 469383:CWOE_RS22470
uniprot id: D3F7Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

469383:CWOE RS00650
gene id: 469383:CWOE_RS00650
uniprot id: D3F4Y6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

469383:CWOE RS13100
gene id: 469383:CWOE_RS13100
uniprot id: D3F8T2
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

469383:CWOE RS11130
gene id: 469383:CWOE_RS11130
uniprot id: D3F5J0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

469383:CWOE RS23045
gene id: 469383:CWOE_RS23045
uniprot id: D3F906
names: Similarity
messages: Belongs to the peptidase M16 family.

469383:CWOE RS06815
gene id: 469383:CWOE_RS06815
uniprot id: D3EYR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

469383:CWOE RS23560
gene id: 469383:CWOE_RS23560
uniprot id: D3FA09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

469383:CWOE RS23590
gene id: 469383:CWOE_RS23590
uniprot id: D3FA15
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS24545
gene id: 469383:CWOE_RS24545
uniprot id: D3FBA9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

469383:CWOE RS19035
gene id: 469383:CWOE_RS19035
uniprot id: D3F2F1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS13435
gene id: 469383:CWOE_RS13435
uniprot id: D3F9Q2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS10910
gene id: 469383:CWOE_RS10910
uniprot id: D3F5E6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469383:CWOE RS14930
gene id: 469383:CWOE_RS14930
uniprot id: D3FBZ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

469383:CWOE RS19645
gene id: 469383:CWOE_RS19645
uniprot id: D3F3H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS23605
gene id: 469383:CWOE_RS23605
uniprot id: D3FA18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS24715
gene id: 469383:CWOE_RS24715
uniprot id: D3FC40
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS11925
gene id: 469383:CWOE_RS11925
uniprot id: D3F7F5
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS03590
gene id: 469383:CWOE_RS03590
uniprot id: D3F9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS15830
gene id: 469383:CWOE_RS15830
uniprot id: D3FDX4
names: Similarity
messages: Belongs to the LOG family.

469383:CWOE RS28980
gene id: 469383:CWOE_RS28980
uniprot id: D3F2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

469383:CWOE RS13165
gene id: 469383:CWOE_RS13165
uniprot id: D3F9J7
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS16295
gene id: 469383:CWOE_RS16295
uniprot id: D3FEW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS28510
gene id: 469383:CWOE_RS28510
uniprot id: D3F1P9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

469383:CWOE RS20960
gene id: 469383:CWOE_RS20960
uniprot id: D3F5P3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS08125
gene id: 469383:CWOE_RS08125
uniprot id: D3F0Y0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS04865
gene id: 469383:CWOE_RS04865
uniprot id: D3FBN7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

469383:CWOE RS17720
gene id: 469383:CWOE_RS17720
uniprot id: D3F0A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

469383:CWOE RS08430
gene id: 469383:CWOE_RS08430
uniprot id: D3F141
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS14910
gene id: 469383:CWOE_RS14910
uniprot id: D3FBZ3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS22690
gene id: 469383:CWOE_RS22690
uniprot id: D3F837
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

469383:CWOE RS15345
gene id: 469383:CWOE_RS15345
uniprot id: D3FCY2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

469383:CWOE RS18820
gene id: 469383:CWOE_RS18820
uniprot id: D3F1L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

469383:CWOE RS21265
gene id: 469383:CWOE_RS21265
uniprot id: D3F5V2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS28195
gene id: 469383:CWOE_RS28195
uniprot id: D3F0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

469383:CWOE RS09000
gene id: 469383:CWOE_RS09000
uniprot id: D3F254
names: Similarity
messages: Belongs to the type IA topoisomerase family.

469383:CWOE RS10245
gene id: 469383:CWOE_RS10245
uniprot id: D3F4B0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469383:CWOE RS11105
gene id: 469383:CWOE_RS11105
uniprot id: D3F5I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS01120
gene id: 469383:CWOE_RS01120
uniprot id: D3F5Y6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS11505
gene id: 469383:CWOE_RS11505
uniprot id: D3F6G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS18635
gene id: 469383:CWOE_RS18635
uniprot id: D3F1H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

469383:CWOE RS26245
gene id: 469383:CWOE_RS26245
uniprot id: D3FEE3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS06390
gene id: 469383:CWOE_RS06390
uniprot id: D3FEM9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS17640
gene id: 469383:CWOE_RS17640
uniprot id: D3F089
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

469383:CWOE RS22755
gene id: 469383:CWOE_RS22755
uniprot id: D3F8U9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS23565
gene id: 469383:CWOE_RS23565
uniprot id: D3FA10
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

469383:CWOE RS00130
gene id: 469383:CWOE_RS00130
uniprot id: D3F3X8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

469383:CWOE RS18260
gene id: 469383:CWOE_RS18260
uniprot id: D3F1A1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS04880
gene id: 469383:CWOE_RS04880
uniprot id: D3FBP0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00080
gene id: 469383:CWOE_RS00080
uniprot id: D3EYP7
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS21495
gene id: 469383:CWOE_RS21495
uniprot id: D3F6P9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS28230
gene id: 469383:CWOE_RS28230
uniprot id: D3F0U1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS24670
gene id: 469383:CWOE_RS24670
uniprot id: D3FC31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

469383:CWOE RS31565
gene id: 469383:CWOE_RS31565
uniprot id: D3FFG5
names: Similarity
messages: Belongs to the peptidase S8 family.

469383:CWOE RS03990
gene id: 469383:CWOE_RS03990
uniprot id: D3FAG4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

469383:CWOE RS05190
gene id: 469383:CWOE_RS05190
uniprot id: D3FCJ7
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS05840
gene id: 469383:CWOE_RS05840
uniprot id: D3FDM5
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

469383:CWOE RS06720
gene id: 469383:CWOE_RS06720
uniprot id: D3FEU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

469383:CWOE RS12530
gene id: 469383:CWOE_RS12530
uniprot id: D3F8H1
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

469383:CWOE RS00020
gene id: 469383:CWOE_RS00020
uniprot id: D3EYQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

469383:CWOE RS21800
gene id: 469383:CWOE_RS21800
uniprot id: D3F6W1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS23035
gene id: 469383:CWOE_RS23035
uniprot id: D3F904
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

469383:CWOE RS13510
gene id: 469383:CWOE_RS13510
uniprot id: D3F9R6
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS06620
gene id: 469383:CWOE_RS06620
uniprot id: D3FES7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

469383:CWOE RS15910
gene id: 469383:CWOE_RS15910
uniprot id: D3FDZ0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

469383:CWOE RS17100
gene id: 469383:CWOE_RS17100
uniprot id: D3EZ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS07655
gene id: 469383:CWOE_RS07655
uniprot id: D3EZY4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

469383:CWOE RS27335
gene id: 469383:CWOE_RS27335
uniprot id: D3EZK9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

469383:CWOE RS18640
gene id: 469383:CWOE_RS18640
uniprot id: D3F1H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

469383:CWOE RS27305
gene id: 469383:CWOE_RS27305
uniprot id: D3EZK3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS29930
gene id: 469383:CWOE_RS29930
uniprot id: D3F416
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

469383:CWOE RS11825
gene id: 469383:CWOE_RS11825
uniprot id: D3F6N0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS14770
gene id: 469383:CWOE_RS14770
uniprot id: D3FBW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

469383:CWOE RS22980
gene id: 469383:CWOE_RS22980
uniprot id: D3F8Z3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS18505
gene id: 469383:CWOE_RS18505
uniprot id: D3F1F1
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

469383:CWOE RS16565
gene id: 469383:CWOE_RS16565
uniprot id: D3FF19
names: Similarity
messages: Belongs to the peptidase S8 family.

469383:CWOE RS04805
gene id: 469383:CWOE_RS04805
uniprot id: D3FBM5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS27740
gene id: 469383:CWOE_RS27740
uniprot id: D3F0J4
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

469383:CWOE RS03105
gene id: 469383:CWOE_RS03105
uniprot id: D3F989
names: Similarity
messages: Belongs to the LacAB/RpiB family.

469383:CWOE RS17970
gene id: 469383:CWOE_RS17970
uniprot id: D3F0F1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

469383:CWOE RS14270
gene id: 469383:CWOE_RS14270
uniprot id: D3FAW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

469383:CWOE RS26885
gene id: 469383:CWOE_RS26885
uniprot id: D3FFG7
names: Similarity
messages: Belongs to the universal stress protein A family.

469383:CWOE RS23325
gene id: 469383:CWOE_RS23325
uniprot id: D3F962
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

469383:CWOE RS22215
gene id: 469383:CWOE_RS22215
uniprot id: D3F7U7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

469383:CWOE RS23900
gene id: 469383:CWOE_RS23900
uniprot id: D3FA75
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

469383:CWOE RS04890
gene id: 469383:CWOE_RS04890
uniprot id: D3FCD8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

469383:CWOE RS10915
gene id: 469383:CWOE_RS10915
uniprot id: D3F5E7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

469383:CWOE RS06805
gene id: 469383:CWOE_RS06805
uniprot id: D3FEW3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

469383:CWOE RS18270
gene id: 469383:CWOE_RS18270
uniprot id: D3F1A3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00575
gene id: 469383:CWOE_RS00575
uniprot id: D3F4X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS16535
gene id: 469383:CWOE_RS16535
uniprot id: D3FF13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS03275
gene id: 469383:CWOE_RS03275
uniprot id: D3F9C4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS06795
gene id: 469383:CWOE_RS06795
uniprot id: D3FEW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

469383:CWOE RS22030
gene id: 469383:CWOE_RS22030
uniprot id: D3F706
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

469383:CWOE RS11980
gene id: 469383:CWOE_RS11980
uniprot id: D3F7G5
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

469383:CWOE RS03705
gene id: 469383:CWOE_RS03705
uniprot id: D3FAA6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS26585
gene id: 469383:CWOE_RS26585
uniprot id: D3FFB0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS29480
gene id: 469383:CWOE_RS29480
uniprot id: D3F2Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

469383:CWOE RS18100
gene id: 469383:CWOE_RS18100
uniprot id: D3F0H6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

469383:CWOE RS06560
gene id: 469383:CWOE_RS06560
uniprot id: D3FER4
names: Similarity
messages: Belongs to the CFA/CMAS family.

469383:CWOE RS25300
gene id: 469383:CWOE_RS25300
uniprot id: D3FD61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS11290
gene id: 469383:CWOE_RS11290
uniprot id: D3F6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS22440
gene id: 469383:CWOE_RS22440
uniprot id: D3F7Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

469383:CWOE RS24305
gene id: 469383:CWOE_RS24305
uniprot id: D3FB60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

469383:CWOE RS04870
gene id: 469383:CWOE_RS04870
uniprot id: D3FBN8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

469383:CWOE RS04985
gene id: 469383:CWOE_RS04985
uniprot id: D3FCF7
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

469383:CWOE RS16035
gene id: 469383:CWOE_RS16035
uniprot id: D3FE14
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS18470
gene id: 469383:CWOE_RS18470
uniprot id: D3F1E4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

469383:CWOE RS17700
gene id: 469383:CWOE_RS17700
uniprot id: D3F098
names: Similarity
messages: Belongs to the UPF0047 family.

469383:CWOE RS21860
gene id: 469383:CWOE_RS21860
uniprot id: D3F6X3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS04505
gene id: 469383:CWOE_RS04505
uniprot id: D3FBG5
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00100
gene id: 469383:CWOE_RS00100
uniprot id: D3EYQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

469383:CWOE RS22060
gene id: 469383:CWOE_RS22060
uniprot id: D3F7R6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

469383:CWOE RS07800
gene id: 469383:CWOE_RS07800
uniprot id: D3F013
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

469383:CWOE RS10200
gene id: 469383:CWOE_RS10200
uniprot id: D3F4A1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS06100
gene id: 469383:CWOE_RS06100
uniprot id: D3FDS2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS11715
gene id: 469383:CWOE_RS11715
uniprot id: D3F6K8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS29740
gene id: 469383:CWOE_RS29740
uniprot id: D3F3U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

469383:CWOE RS23595
gene id: 469383:CWOE_RS23595
uniprot id: D3FA16
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469383:CWOE RS01170
gene id: 469383:CWOE_RS01170
uniprot id: D3F5Z6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

469383:CWOE RS22780
gene id: 469383:CWOE_RS22780
uniprot id: D3F8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

469383:CWOE RS27905
gene id: 469383:CWOE_RS27905
uniprot id: D3F0M7
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS20005
gene id: 469383:CWOE_RS20005
uniprot id: D3F3P2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS10845
gene id: 469383:CWOE_RS10845
uniprot id: D3F5D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS11355
gene id: 469383:CWOE_RS11355
uniprot id: D3F6D6
names: Similarity
messages: Belongs to the ArsC family.

469383:CWOE RS07865
gene id: 469383:CWOE_RS07865
uniprot id: D3F027
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469383:CWOE RS13245
gene id: 469383:CWOE_RS13245
uniprot id: D3F9L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

469383:CWOE RS08270
gene id: 469383:CWOE_RS08270
uniprot id: D3F110
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS04555
gene id: 469383:CWOE_RS04555
uniprot id: D3FBH5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

469383:CWOE RS23680
gene id: 469383:CWOE_RS23680
uniprot id: D3FA31
names: Subcellular Location Annotation
messages: Cytoplasm

469383:CWOE RS10740
gene id: 469383:CWOE_RS10740
uniprot id: D3F5B2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS09510
gene id: 469383:CWOE_RS09510
uniprot id: D3F355
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

469383:CWOE RS26735
gene id: 469383:CWOE_RS26735
uniprot id: D3FFD9
names: Similarity
messages: Belongs to the peptidase M29 family.

469383:CWOE RS14745
gene id: 469383:CWOE_RS14745
uniprot id: D3FBW0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS05060
gene id: 469383:CWOE_RS05060
uniprot id: D3FCH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

469383:CWOE RS27105
gene id: 469383:CWOE_RS27105
uniprot id: D3EZG5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

469383:CWOE RS29770
gene id: 469383:CWOE_RS29770
uniprot id: D3F3V3
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

469383:CWOE RS13075
gene id: 469383:CWOE_RS13075
uniprot id: D3F8S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS20785
gene id: 469383:CWOE_RS20785
uniprot id: D3F4V1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS18065
gene id: 469383:CWOE_RS18065
uniprot id: D3F0G9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS28135
gene id: 469383:CWOE_RS28135
uniprot id: D3F0S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS22930
gene id: 469383:CWOE_RS22930
uniprot id: D3F8Y4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

469383:CWOE RS16685
gene id: 469383:CWOE_RS16685
uniprot id: D3FF42
names: Similarity
messages: Belongs to the CdaR family.

469383:CWOE RS27760
gene id: 469383:CWOE_RS27760
uniprot id: D3F0J8
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS16110
gene id: 469383:CWOE_RS16110
uniprot id: D3FE29
names: Similarity
messages: Belongs to the ribF family.

469383:CWOE RS02200
gene id: 469383:CWOE_RS02200
uniprot id: D3F7A5
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

469383:CWOE RS28465
gene id: 469383:CWOE_RS28465
uniprot id: D3F1P0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS18030
gene id: 469383:CWOE_RS18030
uniprot id: D3F0G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469383:CWOE RS19885
gene id: 469383:CWOE_RS19885
uniprot id: D3F3L9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS23215
gene id: 469383:CWOE_RS23215
uniprot id: D3F940
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

469383:CWOE RS13610
gene id: 469383:CWOE_RS13610
uniprot id: D3F9T6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

469383:CWOE RS15480
gene id: 469383:CWOE_RS15480
uniprot id: D3FD09
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

469383:CWOE RS27795
gene id: 469383:CWOE_RS27795
uniprot id: D3F0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS02045
gene id: 469383:CWOE_RS02045
uniprot id: D3F773
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

469383:CWOE RS24850
gene id: 469383:CWOE_RS24850
uniprot id: D3FC67
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS06750
gene id: 469383:CWOE_RS06750
uniprot id: D3FEV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

469383:CWOE RS02360
gene id: 469383:CWOE_RS02360
uniprot id: D3F7D7
names: Similarity
messages: Belongs to the YciI family.

469383:CWOE RS05880
gene id: 469383:CWOE_RS05880
uniprot id: D3FDN3
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

469383:CWOE RS06840
gene id: 469383:CWOE_RS06840
uniprot id: D3EYS1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

469383:CWOE RS26395
gene id: 469383:CWOE_RS26395
uniprot id: D3FEH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469383:CWOE RS00175
gene id: 469383:CWOE_RS00175
uniprot id: D3F3Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

469383:CWOE RS05490
gene id: 469383:CWOE_RS05490
uniprot id: D3FCQ6
names: Similarity
messages: Belongs to the DEAD box helicase family.

469383:CWOE RS30595
gene id: 469383:CWOE_RS30595
uniprot id: D3F6K7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS23720
gene id: 469383:CWOE_RS23720
uniprot id: D3FA39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS02255
gene id: 469383:CWOE_RS02255
uniprot id: D3F7B6
names: Similarity
messages: Belongs to the group II decarboxylase family.

469383:CWOE RS16370
gene id: 469383:CWOE_RS16370
uniprot id: D3FEX9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

469383:CWOE RS11775
gene id: 469383:CWOE_RS11775
uniprot id: D3F6M0
names: Similarity
messages: Belongs to the sulfatase family.

469383:CWOE RS24020
gene id: 469383:CWOE_RS24020
uniprot id: D3FB02
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS12245
gene id: 469383:CWOE_RS12245
uniprot id: D3F7L8
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

469383:CWOE RS04565
gene id: 469383:CWOE_RS04565
uniprot id: D3FBH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS11590
gene id: 469383:CWOE_RS11590
uniprot id: D3F6I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS25245
gene id: 469383:CWOE_RS25245
uniprot id: D3FD49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

469383:CWOE RS01925
gene id: 469383:CWOE_RS01925
uniprot id: D3F748
names: Similarity
messages: Belongs to the AHA1 family.

469383:CWOE RS00265
gene id: 469383:CWOE_RS00265
uniprot id: D3F406
names: Similarity
messages: Belongs to the MotB family.

469383:CWOE RS17625
gene id: 469383:CWOE_RS17625
uniprot id: D3F086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

469383:CWOE RS03190
gene id: 469383:CWOE_RS03190
uniprot id: D3F9A6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS20995
gene id: 469383:CWOE_RS20995
uniprot id: D3F5Q0
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

469383:CWOE RS29430
gene id: 469383:CWOE_RS29430
uniprot id: D3F2Y1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

469383:CWOE RS02565
gene id: 469383:CWOE_RS02565
uniprot id: D3F877
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

469383:CWOE RS01200
gene id: 469383:CWOE_RS01200
uniprot id: D3F602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS28935
gene id: 469383:CWOE_RS28935
uniprot id: D3F1Y2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS14180
gene id: 469383:CWOE_RS14180
uniprot id: D3FAU8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

469383:CWOE RS23955
gene id: 469383:CWOE_RS23955
uniprot id: D3FA86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

469383:CWOE RS19960
gene id: 469383:CWOE_RS19960
uniprot id: D3F3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS21605
gene id: 469383:CWOE_RS21605
uniprot id: D3F6S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

469383:CWOE RS06855
gene id: 469383:CWOE_RS06855
uniprot id: D3EYS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

469383:CWOE RS30465
gene id: 469383:CWOE_RS30465
uniprot id: D3F213
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

469383:CWOE RS08915
gene id: 469383:CWOE_RS08915
uniprot id: D3F236
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

469383:CWOE RS15420
gene id: 469383:CWOE_RS15420
uniprot id: D3FCZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

469383:CWOE RS06420
gene id: 469383:CWOE_RS06420
uniprot id: D3FEN5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS05975
gene id: 469383:CWOE_RS05975
uniprot id: D3FDP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS02690
gene id: 469383:CWOE_RS02690
uniprot id: D3F8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

469383:CWOE RS10195
gene id: 469383:CWOE_RS10195
uniprot id: D3F4A0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469383:CWOE RS06785
gene id: 469383:CWOE_RS06785
uniprot id: D3FEV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

469383:CWOE RS27515
gene id: 469383:CWOE_RS27515
uniprot id: D3EZP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS05725
gene id: 469383:CWOE_RS05725
uniprot id: D3FDK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

469383:CWOE RS09730
gene id: 469383:CWOE_RS09730
uniprot id: D3F399
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

469383:CWOE RS17795
gene id: 469383:CWOE_RS17795
uniprot id: D3F0B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

469383:CWOE RS06835
gene id: 469383:CWOE_RS06835
uniprot id: D3EYS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

469383:CWOE RS23200
gene id: 469383:CWOE_RS23200
uniprot id: D3F937
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

469383:CWOE RS22150
gene id: 469383:CWOE_RS22150
uniprot id: D3F7T4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS23835
gene id: 469383:CWOE_RS23835
uniprot id: D3FA62
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS25280
gene id: 469383:CWOE_RS25280
uniprot id: D3FD57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS17815
gene id: 469383:CWOE_RS17815
uniprot id: D3F0C1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS17635
gene id: 469383:CWOE_RS17635
uniprot id: D3F088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

469383:CWOE RS29870
gene id: 469383:CWOE_RS29870
uniprot id: D3F3X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

469383:CWOE RS17965
gene id: 469383:CWOE_RS17965
uniprot id: D3F0F0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

469383:CWOE RS13540
gene id: 469383:CWOE_RS13540
uniprot id: D3F9S2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS23575
gene id: 469383:CWOE_RS23575
uniprot id: D3FA12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

469383:CWOE RS26515
gene id: 469383:CWOE_RS26515
uniprot id: D3FF96
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

469383:CWOE RS29545
gene id: 469383:CWOE_RS29545
uniprot id: D3F304
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

469383:CWOE RS18405
gene id: 469383:CWOE_RS18405
uniprot id: D3F1D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

469383:CWOE RS19820
gene id: 469383:CWOE_RS19820
uniprot id: D3F3K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS17355
gene id: 469383:CWOE_RS17355
uniprot id: D3EZC7
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS16105
gene id: 469383:CWOE_RS16105
uniprot id: D3FE28
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

469383:CWOE RS22685
gene id: 469383:CWOE_RS22685
uniprot id: D3F836
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469383:CWOE RS28240
gene id: 469383:CWOE_RS28240
uniprot id: D3F0U3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS03285
gene id: 469383:CWOE_RS03285
uniprot id: D3F9C6
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00550
gene id: 469383:CWOE_RS00550
uniprot id: D3F4W6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

469383:CWOE RS06600
gene id: 469383:CWOE_RS06600
uniprot id: D3FES2
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

469383:CWOE RS14845
gene id: 469383:CWOE_RS14845
uniprot id: D3FBY0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

469383:CWOE RS25895
gene id: 469383:CWOE_RS25895
uniprot id: D3FE79
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

469383:CWOE RS28915
gene id: 469383:CWOE_RS28915
uniprot id: D3F1X8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

469383:CWOE RS06845
gene id: 469383:CWOE_RS06845
uniprot id: D3EYS2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

469383:CWOE RS19630
gene id: 469383:CWOE_RS19630
uniprot id: D3F3G9
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

469383:CWOE RS00165
gene id: 469383:CWOE_RS00165
uniprot id: D3F3Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

469383:CWOE RS25550
gene id: 469383:CWOE_RS25550
uniprot id: D3FDB0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS23295
gene id: 469383:CWOE_RS23295
uniprot id: D3F956
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

469383:CWOE RS04380
gene id: 469383:CWOE_RS04380
uniprot id: D3FBE0
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS25685
gene id: 469383:CWOE_RS25685
uniprot id: D3FDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS12495
gene id: 469383:CWOE_RS12495
uniprot id: D3F8G4
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

469383:CWOE RS03665
gene id: 469383:CWOE_RS03665
uniprot id: D3FA98
names: Similarity
messages: Belongs to the UPF0145 family.

469383:CWOE RS13715
gene id: 469383:CWOE_RS13715
uniprot id: D3F9V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

469383:CWOE RS14150
gene id: 469383:CWOE_RS14150
uniprot id: D3FAU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

469383:CWOE RS16475
gene id: 469383:CWOE_RS16475
uniprot id: D3FF01
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS16590
gene id: 469383:CWOE_RS16590
uniprot id: D3FF24
names: Similarity
messages: Belongs to the YciI family.

469383:CWOE RS22325
gene id: 469383:CWOE_RS22325
uniprot id: D3F7W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

469383:CWOE RS16645
gene id: 469383:CWOE_RS16645
uniprot id: D3FF35
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS17805
gene id: 469383:CWOE_RS17805
uniprot id: D3F0B9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

469383:CWOE RS01755
gene id: 469383:CWOE_RS01755
uniprot id: D3F714
names: Similarity
messages: Belongs to the YciI family.

469383:CWOE RS18600
gene id: 469383:CWOE_RS18600
uniprot id: D3F1H0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS24135
gene id: 469383:CWOE_RS24135
uniprot id: D3FB26
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS14695
gene id: 469383:CWOE_RS14695
uniprot id: D3FBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS28860
gene id: 469383:CWOE_RS28860
uniprot id: D3F1W7
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

469383:CWOE RS29180
gene id: 469383:CWOE_RS29180
uniprot id: D3F2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

469383:CWOE RS19615
gene id: 469383:CWOE_RS19615
uniprot id: D3F3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

469383:CWOE RS13875
gene id: 469383:CWOE_RS13875
uniprot id: D3FAN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS28900
gene id: 469383:CWOE_RS28900
uniprot id: D3F1X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS22735
gene id: 469383:CWOE_RS22735
uniprot id: D3F8U5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

469383:CWOE RS14340
gene id: 469383:CWOE_RS14340
uniprot id: D3FAY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

469383:CWOE RS17585
gene id: 469383:CWOE_RS17585
uniprot id: D3F078
names: Similarity
messages: Belongs to the YggT family.

469383:CWOE RS00355
gene id: 469383:CWOE_RS00355
uniprot id: D3F423
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

469383:CWOE RS13695
gene id: 469383:CWOE_RS13695
uniprot id: D3F9V3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS29570
gene id: 469383:CWOE_RS29570
uniprot id: D3F309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS26510
gene id: 469383:CWOE_RS26510
uniprot id: D3FF95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

469383:CWOE RS27205
gene id: 469383:CWOE_RS27205
uniprot id: D3EZI4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS29550
gene id: 469383:CWOE_RS29550
uniprot id: D3F305
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

469383:CWOE RS18285
gene id: 469383:CWOE_RS18285
uniprot id: D3F1A6
names: Similarity
messages: Belongs to the MYG1 family.

469383:CWOE RS07755
gene id: 469383:CWOE_RS07755
uniprot id: D3F004
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS18435
gene id: 469383:CWOE_RS18435
uniprot id: D3F1D7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

469383:CWOE RS08355
gene id: 469383:CWOE_RS08355
uniprot id: D3F126
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

469383:CWOE RS03885
gene id: 469383:CWOE_RS03885
uniprot id: D3FAE2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

469383:CWOE RS23115
gene id: 469383:CWOE_RS23115
uniprot id: D3F920
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469383:CWOE RS07340
gene id: 469383:CWOE_RS07340
uniprot id: D3EZ21
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS17480
gene id: 469383:CWOE_RS17480
uniprot id: D3EZF2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS18895
gene id: 469383:CWOE_RS18895
uniprot id: D3F2C5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS28650
gene id: 469383:CWOE_RS28650
uniprot id: D3F1S5
names: Similarity
messages: Belongs to the peptidase C15 family.

469383:CWOE RS12395
gene id: 469383:CWOE_RS12395
uniprot id: D3F7P6
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS22345
gene id: 469383:CWOE_RS22345
uniprot id: D3F7X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS18770
gene id: 469383:CWOE_RS18770
uniprot id: D3F1K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS11755
gene id: 469383:CWOE_RS11755
uniprot id: D3F6L6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469383:CWOE RS13945
gene id: 469383:CWOE_RS13945
uniprot id: D3FAQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

469383:CWOE RS21580
gene id: 469383:CWOE_RS21580
uniprot id: D3F6R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

469383:CWOE RS26135
gene id: 469383:CWOE_RS26135
uniprot id: D3FEC2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

469383:CWOE RS02150
gene id: 469383:CWOE_RS02150
uniprot id: D3F795
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS17000
gene id: 469383:CWOE_RS17000
uniprot id: D3EZ57
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

469383:CWOE RS16160
gene id: 469383:CWOE_RS16160
uniprot id: D3FE39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

469383:CWOE RS15985
gene id: 469383:CWOE_RS15985
uniprot id: D3FE04
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS03670
gene id: 469383:CWOE_RS03670
uniprot id: D3FA99
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS12750
gene id: 469383:CWOE_RS12750
uniprot id: D3F8L4
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS01165
gene id: 469383:CWOE_RS01165
uniprot id: D3F5Z5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS00450
gene id: 469383:CWOE_RS00450
uniprot id: D3F441
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

469383:CWOE RS15845
gene id: 469383:CWOE_RS15845
uniprot id: D3FDX7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

469383:CWOE RS29715
gene id: 469383:CWOE_RS29715
uniprot id: D3F3U2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

469383:CWOE RS07105
gene id: 469383:CWOE_RS07105
uniprot id: D3EYX4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS17365
gene id: 469383:CWOE_RS17365
uniprot id: D3EZC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

469383:CWOE RS03555
gene id: 469383:CWOE_RS03555
uniprot id: D3F9H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

469383:CWOE RS03605
gene id: 469383:CWOE_RS03605
uniprot id: D3F9I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

469383:CWOE RS09275
gene id: 469383:CWOE_RS09275
uniprot id: D3F2B1
names: Similarity
messages: Belongs to the histone deacetylase family.

469383:CWOE RS22655
gene id: 469383:CWOE_RS22655
uniprot id: D3F831
names: Similarity
messages: Belongs to the SUI1 family.

469383:CWOE RS21960
gene id: 469383:CWOE_RS21960
uniprot id: D3F6Z3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS08380
gene id: 469383:CWOE_RS08380
uniprot id: D3F131
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

469383:CWOE RS30375
gene id: 469383:CWOE_RS30375
uniprot id: D3EZV1
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS11215
gene id: 469383:CWOE_RS11215
uniprot id: D3F5K7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469383:CWOE RS18055
gene id: 469383:CWOE_RS18055
uniprot id: D3F0G7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS12030
gene id: 469383:CWOE_RS12030
uniprot id: D3F7H5
names: Similarity
messages: Belongs to the selenium-binding protein family.

469383:CWOE RS06445
gene id: 469383:CWOE_RS06445
uniprot id: D3FEP0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

469383:CWOE RS05195
gene id: 469383:CWOE_RS05195
uniprot id: D3FCJ8
names: Similarity
messages: Belongs to the UPF0047 family.

469383:CWOE RS00410
gene id: 469383:CWOE_RS00410
uniprot id: D3F433
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS28235
gene id: 469383:CWOE_RS28235
uniprot id: D3F0U2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

469383:CWOE RS17125
gene id: 469383:CWOE_RS17125
uniprot id: D3EZ82
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS23210
gene id: 469383:CWOE_RS23210
uniprot id: D3F939
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

469383:CWOE RS03045
gene id: 469383:CWOE_RS03045
uniprot id: D3F976
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS26380
gene id: 469383:CWOE_RS26380
uniprot id: D3FEH0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

469383:CWOE RS29920
gene id: 469383:CWOE_RS29920
uniprot id: D3F3Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS32555
gene id: 469383:CWOE_RS32555
uniprot id: D3EYT9
names: Similarity
messages: Belongs to the peptidase S13 family.

469383:CWOE RS08450
gene id: 469383:CWOE_RS08450
uniprot id: D3F144
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

469383:CWOE RS13265
gene id: 469383:CWOE_RS13265
uniprot id: D3F9L9
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS03185
gene id: 469383:CWOE_RS03185
uniprot id: D3F9A5
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS05810
gene id: 469383:CWOE_RS05810
uniprot id: D3FDL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

469383:CWOE RS03270
gene id: 469383:CWOE_RS03270
uniprot id: D3F9C3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS26680
gene id: 469383:CWOE_RS26680
uniprot id: D3FFD0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS09375
gene id: 469383:CWOE_RS09375
uniprot id: D3F327
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

469383:CWOE RS20095
gene id: 469383:CWOE_RS20095
uniprot id: D3F3R0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469383:CWOE RS29630
gene id: 469383:CWOE_RS29630
uniprot id: D3F3S6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

469383:CWOE RS04915
gene id: 469383:CWOE_RS04915
uniprot id: D3FCE3
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS02725
gene id: 469383:CWOE_RS02725
uniprot id: D3F8A9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469383:CWOE RS11795
gene id: 469383:CWOE_RS11795
uniprot id: D3F6M4
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

469383:CWOE RS08930
gene id: 469383:CWOE_RS08930
uniprot id: D3F240
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

469383:CWOE RS20965
gene id: 469383:CWOE_RS20965
uniprot id: D3F5P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

469383:CWOE RS15980
gene id: 469383:CWOE_RS15980
uniprot id: D3FE03
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

469383:CWOE RS06275
gene id: 469383:CWOE_RS06275
uniprot id: D3FEK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS29125
gene id: 469383:CWOE_RS29125
uniprot id: D3F2S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS29700
gene id: 469383:CWOE_RS29700
uniprot id: D3F3T9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

469383:CWOE RS04100
gene id: 469383:CWOE_RS04100
uniprot id: D3FAI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

469383:CWOE RS23255
gene id: 469383:CWOE_RS23255
uniprot id: D3F948
names: Similarity
messages: Belongs to the LacAB/RpiB family.

469383:CWOE RS17225
gene id: 469383:CWOE_RS17225
uniprot id: D3EZA1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

469383:CWOE RS18365
gene id: 469383:CWOE_RS18365
uniprot id: D3F1C3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469383:CWOE RS02535
gene id: 469383:CWOE_RS02535
uniprot id: D3F871
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

469383:CWOE RS21025
gene id: 469383:CWOE_RS21025
uniprot id: D3F5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS15560
gene id: 469383:CWOE_RS15560
uniprot id: D3FD24
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS24210
gene id: 469383:CWOE_RS24210
uniprot id: D3FB41
names: Similarity
messages: Belongs to the thioesterase PaaI family.

469383:CWOE RS18785
gene id: 469383:CWOE_RS18785
uniprot id: D3F1K6
names: Similarity
messages: Belongs to the cytochrome P450 family.

469383:CWOE RS12860
gene id: 469383:CWOE_RS12860
uniprot id: D3F8N5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

469383:CWOE RS18810
gene id: 469383:CWOE_RS18810
uniprot id: D3F1L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

469383:CWOE RS29725
gene id: 469383:CWOE_RS29725
uniprot id: D3F3U4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469383:CWOE RS06105
gene id: 469383:CWOE_RS06105
uniprot id: D3FDS3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

469383:CWOE RS02715
gene id: 469383:CWOE_RS02715
uniprot id: D3F8A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469383:CWOE RS23225
gene id: 469383:CWOE_RS23225
uniprot id: D3F942
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

469383:CWOE RS18250
gene id: 469383:CWOE_RS18250
uniprot id: D3F199
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

469383:CWOE RS09205
gene id: 469383:CWOE_RS09205
uniprot id: D3F297
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

469383:CWOE RS00270
gene id: 469383:CWOE_RS00270
uniprot id: D3F407
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

469383:CWOE RS28955
gene id: 469383:CWOE_RS28955
uniprot id: D3F1Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

469383:CWOE RS19745
gene id: 469383:CWOE_RS19745
uniprot id: D3F3J2
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS00895
gene id: 469383:CWOE_RS00895
uniprot id: D3F537
names: Similarity
messages: Belongs to the DSD1 family.

469383:CWOE RS22480
gene id: 469383:CWOE_RS22480
uniprot id: D3F7Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

469383:CWOE RS01045
gene id: 469383:CWOE_RS01045
uniprot id: D3F567
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS10550
gene id: 469383:CWOE_RS10550
uniprot id: D3F4G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469383:CWOE RS23855
gene id: 469383:CWOE_RS23855
uniprot id: D3FA66
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

469383:CWOE RS18745
gene id: 469383:CWOE_RS18745
uniprot id: D3F1J8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

469383:CWOE RS05210
gene id: 469383:CWOE_RS05210
uniprot id: D3FCK1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

469383:CWOE RS24395
gene id: 469383:CWOE_RS24395
uniprot id: D3FB79
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS24585
gene id: 469383:CWOE_RS24585
uniprot id: D3FC14
names: Subcellular Location Annotation
messages: Membrane

469383:CWOE RS17150
gene id: 469383:CWOE_RS17150
uniprot id: D3EZ87
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

469383:CWOE RS12545
gene id: 469383:CWOE_RS12545
uniprot id: D3F8H4
names: Subcellular Location Annotation
messages: Membrane