469382:HBOR RS10920
gene id: 469382:HBOR_RS10920
uniprot id: E4NQF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS11615
gene id: 469382:HBOR_RS11615
uniprot id: E4NRC2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

469382:HBOR RS13820
gene id: 469382:HBOR_RS13820
uniprot id: E4NLV1
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS09880
gene id: 469382:HBOR_RS09880
uniprot id: E4NP74
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS12020
gene id: 469382:HBOR_RS12020
uniprot id: E4NRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

469382:HBOR RS14985
gene id: 469382:HBOR_RS14985
uniprot id: E4NUC1
names: Similarity
messages: Belongs to the AOR/FOR family.

469382:HBOR RS09105
gene id: 469382:HBOR_RS09105
uniprot id: E4NNB9
names: Similarity
messages: Belongs to the SDO1/SBDS family.

469382:HBOR RS02765
gene id: 469382:HBOR_RS02765
uniprot id: E4NML8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

469382:HBOR RS05550
gene id: 469382:HBOR_RS05550
uniprot id: L9V1M4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS05360
gene id: 469382:HBOR_RS05360
uniprot id: L9UZ33
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS01785
gene id: 469382:HBOR_RS01785
uniprot id: E4NKS8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS13650
gene id: 469382:HBOR_RS13650
uniprot id: E4NLR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

469382:HBOR RS18025
gene id: 469382:HBOR_RS18025
uniprot id: E4NW46
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

469382:HBOR RS14835
gene id: 469382:HBOR_RS14835
uniprot id: E4NU90
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS02845
gene id: 469382:HBOR_RS02845
uniprot id: E4NMN4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS04895
gene id: 469382:HBOR_RS04895
uniprot id: E4NQ48
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS10860
gene id: 469382:HBOR_RS10860
uniprot id: E4NQD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS13800
gene id: 469382:HBOR_RS13800
uniprot id: E4NLU7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

469382:HBOR RS00065
gene id: 469382:HBOR_RS00065
uniprot id: E4NR00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

469382:HBOR RS02565
gene id: 469382:HBOR_RS02565
uniprot id: E4NM34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

469382:HBOR RS12440
gene id: 469382:HBOR_RS12440
uniprot id: E4NSN8
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS05400
gene id: 469382:HBOR_RS05400
uniprot id: L9V1J7
names: Caution
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS13715
gene id: 469382:HBOR_RS13715
uniprot id: E4NLS9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS06895
gene id: 469382:HBOR_RS06895
uniprot id: L9UYJ8
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14515
gene id: 469382:HBOR_RS14515
uniprot id: E4NU23
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS00950
gene id: 469382:HBOR_RS00950
uniprot id: E4NSS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

469382:HBOR RS10390
gene id: 469382:HBOR_RS10390
uniprot id: E4NPP7
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS00180
gene id: 469382:HBOR_RS00180
uniprot id: E4NRH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

469382:HBOR RS02610
gene id: 469382:HBOR_RS02610
uniprot id: E4NM43
names: Similarity
messages: Belongs to the SUI1 family.

469382:HBOR RS07600
gene id: 469382:HBOR_RS07600
uniprot id: E4NKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

469382:HBOR RS01905
gene id: 469382:HBOR_RS01905
uniprot id: E4NKV3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

469382:HBOR RS06065
gene id: 469382:HBOR_RS06065
uniprot id: E4NRQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

469382:HBOR RS13755
gene id: 469382:HBOR_RS13755
uniprot id: E4NLT7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS13750
gene id: 469382:HBOR_RS13750
uniprot id: E4NLT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

469382:HBOR RS13705
gene id: 469382:HBOR_RS13705
uniprot id: E4NLS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

469382:HBOR RS03940
gene id: 469382:HBOR_RS03940
uniprot id: E4NNY2
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

469382:HBOR RS04885
gene id: 469382:HBOR_RS04885
uniprot id: E4NQ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

469382:HBOR RS05175
gene id: 469382:HBOR_RS05175
uniprot id: E4NLQ1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

469382:HBOR RS09970
gene id: 469382:HBOR_RS09970
uniprot id: E4NP93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

469382:HBOR RS09875
gene id: 469382:HBOR_RS09875
uniprot id: E4NP73
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS17250
gene id: 469382:HBOR_RS17250
uniprot id: L9UWT5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS13790
gene id: 469382:HBOR_RS13790
uniprot id: E4NLU5
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

469382:HBOR RS13610
gene id: 469382:HBOR_RS13610
uniprot id: E4NLB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

469382:HBOR RS09610
gene id: 469382:HBOR_RS09610
uniprot id: E4NNU6
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS02905
gene id: 469382:HBOR_RS02905
uniprot id: E4NMP5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469382:HBOR RS02050
gene id: 469382:HBOR_RS02050
uniprot id: E4NLD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

469382:HBOR RS15480
gene id: 469382:HBOR_RS15480
uniprot id: E4NUM6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS11645
gene id: 469382:HBOR_RS11645
uniprot id: E4NRC8
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

469382:HBOR RS01925
gene id: 469382:HBOR_RS01925
uniprot id: E4NKV7
names: Similarity
messages: Belongs to the thioesterase PaaI family.

469382:HBOR RS12075
gene id: 469382:HBOR_RS12075
uniprot id: E4NS10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

469382:HBOR RS12110
gene id: 469382:HBOR_RS12110
uniprot id: E4NS17
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

469382:HBOR RS00465
gene id: 469382:HBOR_RS00465
uniprot id: E4NRN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

469382:HBOR RS01230
gene id: 469382:HBOR_RS01230
uniprot id: E4NSX9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

469382:HBOR RS11355
gene id: 469382:HBOR_RS11355
uniprot id: E4NQW4
names: Similarity
messages: Belongs to the glutamate synthase family.

469382:HBOR RS15775
gene id: 469382:HBOR_RS15775
uniprot id: E4NUT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS10355
gene id: 469382:HBOR_RS10355
uniprot id: E4NPP0
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

469382:HBOR RS10590
gene id: 469382:HBOR_RS10590
uniprot id: E4NQ12
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS05605
gene id: 469382:HBOR_RS05605
uniprot id: E4NQR3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

469382:HBOR RS04330
gene id: 469382:HBOR_RS04330
uniprot id: E4NPD9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

469382:HBOR RS04890
gene id: 469382:HBOR_RS04890
uniprot id: E4NQ47
names: Similarity
messages: Belongs to the UPF0045 family.

469382:HBOR RS07375
gene id: 469382:HBOR_RS07375
uniprot id: E4NTP8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

469382:HBOR RS18420
gene id: 469382:HBOR_RS18420
uniprot id: E4NWC7
names: Similarity
messages: Belongs to the thioesterase PaaI family.

469382:HBOR RS03195
gene id: 469382:HBOR_RS03195
uniprot id: E4NN31
names: Similarity
messages: Belongs to the Ahb/Nir family.

469382:HBOR RS18870
gene id: 469382:HBOR_RS18870
uniprot id: E4NWM4
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS12725
gene id: 469382:HBOR_RS12725
uniprot id: L9UKQ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS02415
gene id: 469382:HBOR_RS02415
uniprot id: E4NM03
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

469382:HBOR RS18175
gene id: 469382:HBOR_RS18175
uniprot id: E4NW77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

469382:HBOR RS03665
gene id: 469382:HBOR_RS03665
uniprot id: E4NNK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

469382:HBOR RS12870
gene id: 469382:HBOR_RS12870
uniprot id: E4NTC0
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS17135
gene id: 469382:HBOR_RS17135
uniprot id: E4NV93
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

469382:HBOR RS12455
gene id: 469382:HBOR_RS12455
uniprot id: E4NSP2
names: Similarity
messages: Belongs to the peptidase S8 family.

469382:HBOR RS07390
gene id: 469382:HBOR_RS07390
uniprot id: E4NTQ1
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS03815
gene id: 469382:HBOR_RS03815
uniprot id: E4NNV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS16080
gene id: 469382:HBOR_RS16080
uniprot id: E4NVI4
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS01395
gene id: 469382:HBOR_RS01395
uniprot id: E4NTF3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

469382:HBOR RS09745
gene id: 469382:HBOR_RS09745
uniprot id: E4NP47
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS12820
gene id: 469382:HBOR_RS12820
uniprot id: L9UIQ3
names: Caution
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS11100
gene id: 469382:HBOR_RS11100
uniprot id: E4NQI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

469382:HBOR RS02250
gene id: 469382:HBOR_RS02250
uniprot id: E4NLH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS04935
gene id: 469382:HBOR_RS04935
uniprot id: E4NQ54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

469382:HBOR RS15110
gene id: 469382:HBOR_RS15110
uniprot id: L9UKL1
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS11405
gene id: 469382:HBOR_RS11405
uniprot id: E4NQX3
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

469382:HBOR RS15785
gene id: 469382:HBOR_RS15785
uniprot id: E4NUT8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

469382:HBOR RS10445
gene id: 469382:HBOR_RS10445
uniprot id: L9UG39
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS03865
gene id: 469382:HBOR_RS03865
uniprot id: E4NNW7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

469382:HBOR RS15570
gene id: 469382:HBOR_RS15570
uniprot id: E4NUP5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS08145
gene id: 469382:HBOR_RS08145
uniprot id: E4NLQ1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

469382:HBOR RS13255
gene id: 469382:HBOR_RS13255
uniprot id: E4NTY3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

469382:HBOR RS12085
gene id: 469382:HBOR_RS12085
uniprot id: E4NS12
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS07915
gene id: 469382:HBOR_RS07915
uniprot id: L9UYG1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS06365
gene id: 469382:HBOR_RS06365
uniprot id: L9V066
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS11920
gene id: 469382:HBOR_RS11920
uniprot id: E4NRY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

469382:HBOR RS07610
gene id: 469382:HBOR_RS07610
uniprot id: E4NKZ3
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS05765
gene id: 469382:HBOR_RS05765
uniprot id: E4NR47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

469382:HBOR RS10325
gene id: 469382:HBOR_RS10325
uniprot id: E4NPN4
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS04385
gene id: 469382:HBOR_RS04385
uniprot id: E4NPF0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469382:HBOR RS00915
gene id: 469382:HBOR_RS00915
uniprot id: E4NSR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS10110
gene id: 469382:HBOR_RS10110
uniprot id: E4NPJ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

469382:HBOR RS04980
gene id: 469382:HBOR_RS04980
uniprot id: E4NQ63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

469382:HBOR RS00330
gene id: 469382:HBOR_RS00330
uniprot id: E4NRK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

469382:HBOR RS02215
gene id: 469382:HBOR_RS02215
uniprot id: E4NLG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

469382:HBOR RS03770
gene id: 469382:HBOR_RS03770
uniprot id: E4NNM5
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS13635
gene id: 469382:HBOR_RS13635
uniprot id: E4NLB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

469382:HBOR RS13795
gene id: 469382:HBOR_RS13795
uniprot id: E4NLU6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

469382:HBOR RS00825
gene id: 469382:HBOR_RS00825
uniprot id: E4NS99
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

469382:HBOR RS11620
gene id: 469382:HBOR_RS11620
uniprot id: E4NRC3
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

469382:HBOR RS10910
gene id: 469382:HBOR_RS10910
uniprot id: E4NQE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS04410
gene id: 469382:HBOR_RS04410
uniprot id: E4NPF5
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS15760
gene id: 469382:HBOR_RS15760
uniprot id: E4NUT3
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS08665
gene id: 469382:HBOR_RS08665
uniprot id: E4NMV5
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS02245
gene id: 469382:HBOR_RS02245
uniprot id: E4NLH3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS09220
gene id: 469382:HBOR_RS09220
uniprot id: E4NNE3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469382:HBOR RS02400
gene id: 469382:HBOR_RS02400
uniprot id: E4NM00
names: Similarity
messages: Belongs to the HAM1 NTPase family.

469382:HBOR RS15490
gene id: 469382:HBOR_RS15490
uniprot id: E4NUM8
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

469382:HBOR RS08605
gene id: 469382:HBOR_RS08605
uniprot id: E4NMU2
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

469382:HBOR RS13425
gene id: 469382:HBOR_RS13425
uniprot id: E4NL75
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS18565
gene id: 469382:HBOR_RS18565
uniprot id: E4NWG0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

469382:HBOR RS02590
gene id: 469382:HBOR_RS02590
uniprot id: E4NM39
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

469382:HBOR RS12465
gene id: 469382:HBOR_RS12465
uniprot id: E4NSP4
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS05865
gene id: 469382:HBOR_RS05865
uniprot id: E4NR69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

469382:HBOR RS05595
gene id: 469382:HBOR_RS05595
uniprot id: E4NQR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

469382:HBOR RS09565
gene id: 469382:HBOR_RS09565
uniprot id: E4NNT7
names: Similarity
messages: Belongs to the glutaredoxin family.

469382:HBOR RS09435
gene id: 469382:HBOR_RS09435
uniprot id: E4NNR0
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

469382:HBOR RS01095
gene id: 469382:HBOR_RS01095
uniprot id: E4NSV2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

469382:HBOR RS05200
gene id: 469382:HBOR_RS05200
uniprot id: E4NQA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

469382:HBOR RS11755
gene id: 469382:HBOR_RS11755
uniprot id: E4NRF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

469382:HBOR RS10730
gene id: 469382:HBOR_RS10730
uniprot id: E4NQ40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

469382:HBOR RS08960
gene id: 469382:HBOR_RS08960
uniprot id: E4NN90
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

469382:HBOR RS05545
gene id: 469382:HBOR_RS05545
uniprot id: E4NQQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS11825
gene id: 469382:HBOR_RS11825
uniprot id: E4NRG5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

469382:HBOR RS08710
gene id: 469382:HBOR_RS08710
uniprot id: E4NMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

469382:HBOR RS04690
gene id: 469382:HBOR_RS04690
uniprot id: L9V0E7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS20395
gene id: 469382:HBOR_RS20395
uniprot id: L9UXD4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS02085
gene id: 469382:HBOR_RS02085
uniprot id: E4NLD9
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS15710
gene id: 469382:HBOR_RS15710
uniprot id: E4NUS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Cytoplasm
messages: Gas vesicle
messages: Vesicle

469382:HBOR RS12905
gene id: 469382:HBOR_RS12905
uniprot id: E4NTR9
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS03310
gene id: 469382:HBOR_RS03310
uniprot id: E4NN55
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS08510
gene id: 469382:HBOR_RS08510
uniprot id: E4NMC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

469382:HBOR RS08015
gene id: 469382:HBOR_RS08015
uniprot id: E4NLM5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

469382:HBOR RS11150
gene id: 469382:HBOR_RS11150
uniprot id: E4NQS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the halobacterial S-layer protein family.
messages: Cell membrane
messages: Membrane
messages: S-layer

469382:HBOR RS13200
gene id: 469382:HBOR_RS13200
uniprot id: E4NTX2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

469382:HBOR RS07350
gene id: 469382:HBOR_RS07350
uniprot id: L9UY52
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS02690
gene id: 469382:HBOR_RS02690
uniprot id: L9URH4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS11140
gene id: 469382:HBOR_RS11140
uniprot id: E4NQS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

469382:HBOR RS03435
gene id: 469382:HBOR_RS03435
uniprot id: E4NN81
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

469382:HBOR RS00165
gene id: 469382:HBOR_RS00165
uniprot id: E4NRH3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

469382:HBOR RS06980
gene id: 469382:HBOR_RS06980
uniprot id: E4NT34
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

469382:HBOR RS05345
gene id: 469382:HBOR_RS05345
uniprot id: E4NQL0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

469382:HBOR RS06540
gene id: 469382:HBOR_RS06540
uniprot id: E4NSE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

469382:HBOR RS10790
gene id: 469382:HBOR_RS10790
uniprot id: E4NQC4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

469382:HBOR RS11450
gene id: 469382:HBOR_RS11450
uniprot id: E4NQY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

469382:HBOR RS10405
gene id: 469382:HBOR_RS10405
uniprot id: E4NPX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

469382:HBOR RS12765
gene id: 469382:HBOR_RS12765
uniprot id: E4NT99
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

469382:HBOR RS04995
gene id: 469382:HBOR_RS04995
uniprot id: E4NQ66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

469382:HBOR RS12305
gene id: 469382:HBOR_RS12305
uniprot id: E4NSL0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS08880
gene id: 469382:HBOR_RS08880
uniprot id: E4NMZ9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

469382:HBOR RS06875
gene id: 469382:HBOR_RS06875
uniprot id: E4NT12
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

469382:HBOR RS09885
gene id: 469382:HBOR_RS09885
uniprot id: E4NP75
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS08130
gene id: 469382:HBOR_RS08130
uniprot id: E4NLP8
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS15370
gene id: 469382:HBOR_RS15370
uniprot id: E4NUK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

469382:HBOR RS04680
gene id: 469382:HBOR_RS04680
uniprot id: E4NPT2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

469382:HBOR RS00870
gene id: 469382:HBOR_RS00870
uniprot id: E4NSA8
names: Similarity
messages: Belongs to the cytochrome P450 family.

469382:HBOR RS10410
gene id: 469382:HBOR_RS10410
uniprot id: E4NPX6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

469382:HBOR RS04930
gene id: 469382:HBOR_RS04930
uniprot id: E4NQ53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

469382:HBOR RS17335
gene id: 469382:HBOR_RS17335
uniprot id: E4NVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS11035
gene id: 469382:HBOR_RS11035
uniprot id: E4NQH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS18795
gene id: 469382:HBOR_RS18795
uniprot id: L9UM54
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS11480
gene id: 469382:HBOR_RS11480
uniprot id: E4NR95
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS05435
gene id: 469382:HBOR_RS05435
uniprot id: E4NQM8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

469382:HBOR RS15505
gene id: 469382:HBOR_RS15505
uniprot id: E4NUN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS01725
gene id: 469382:HBOR_RS01725
uniprot id: E4NKR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

469382:HBOR RS19785
gene id: 469382:HBOR_RS19785
uniprot id: L9UEJ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS07520
gene id: 469382:HBOR_RS07520
uniprot id: L9UXK9
names: Caution
names: Similarity
messages: Belongs to the peptidase S9A family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS17070
gene id: 469382:HBOR_RS17070
uniprot id: E4NV81
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469382:HBOR RS11540
gene id: 469382:HBOR_RS11540
uniprot id: E4NRA7
names: Similarity
messages: Belongs to the peptidase S9C family.

469382:HBOR RS16055
gene id: 469382:HBOR_RS16055
uniprot id: E4NVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS06030
gene id: 469382:HBOR_RS06030
uniprot id: E4NRQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

469382:HBOR RS12640
gene id: 469382:HBOR_RS12640
uniprot id: E4NT74
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

469382:HBOR RS02425
gene id: 469382:HBOR_RS02425
uniprot id: E4NM05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

469382:HBOR RS05210
gene id: 469382:HBOR_RS05210
uniprot id: E4NQA8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS07095
gene id: 469382:HBOR_RS07095
uniprot id: E4NT52
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

469382:HBOR RS14715
gene id: 469382:HBOR_RS14715
uniprot id: L9UKX3
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS04515
gene id: 469382:HBOR_RS04515
uniprot id: E4NPP8
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

469382:HBOR RS08760
gene id: 469382:HBOR_RS08760
uniprot id: E4NMX3
names: Subcellular Location Annotation
messages: Cytoplasm

469382:HBOR RS14440
gene id: 469382:HBOR_RS14440
uniprot id: E4NU06
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS03460
gene id: 469382:HBOR_RS03460
uniprot id: E4NNG2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

469382:HBOR RS13350
gene id: 469382:HBOR_RS13350
uniprot id: E4NL59
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

469382:HBOR RS02420
gene id: 469382:HBOR_RS02420
uniprot id: E4NM04
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

469382:HBOR RS19035
gene id: 469382:HBOR_RS19035
uniprot id: E4NWQ9
names: Similarity
messages: Belongs to the GbsR family.

469382:HBOR RS00530
gene id: 469382:HBOR_RS00530
uniprot id: E4NS37
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

469382:HBOR RS08670
gene id: 469382:HBOR_RS08670
uniprot id: E4NMV6
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS18315
gene id: 469382:HBOR_RS18315
uniprot id: L9UND8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS04610
gene id: 469382:HBOR_RS04610
uniprot id: E4NPR8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469382:HBOR RS02095
gene id: 469382:HBOR_RS02095
uniprot id: E4NLE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

469382:HBOR RS12900
gene id: 469382:HBOR_RS12900
uniprot id: E4NTR8
names: Similarity
messages: Belongs to the peptidase C15 family.

469382:HBOR RS10045
gene id: 469382:HBOR_RS10045
uniprot id: L9UGA8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS16690
gene id: 469382:HBOR_RS16690
uniprot id: E4NV04
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

469382:HBOR RS11745
gene id: 469382:HBOR_RS11745
uniprot id: E4NRE8
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

469382:HBOR RS10540
gene id: 469382:HBOR_RS10540
uniprot id: E4NQ02
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS12015
gene id: 469382:HBOR_RS12015
uniprot id: E4NRZ8
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS18205
gene id: 469382:HBOR_RS18205
uniprot id: E4NW83
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

469382:HBOR RS18460
gene id: 469382:HBOR_RS18460
uniprot id: E4NWD8
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

469382:HBOR RS16635
gene id: 469382:HBOR_RS16635
uniprot id: E4NUZ3
names: Subcellular Location Annotation
messages: Cytoplasm

469382:HBOR RS07455
gene id: 469382:HBOR_RS07455
uniprot id: E4NTR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

469382:HBOR RS02225
gene id: 469382:HBOR_RS02225
uniprot id: L9URE4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS16345
gene id: 469382:HBOR_RS16345
uniprot id: E4NVN8
names: Subcellular Location Annotation
messages: Cell membrane

469382:HBOR RS10160
gene id: 469382:HBOR_RS10160
uniprot id: E4NPK0
names: Similarity
messages: Belongs to the peptidase S45 family.

469382:HBOR RS10580
gene id: 469382:HBOR_RS10580
uniprot id: E4NQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

469382:HBOR RS05415
gene id: 469382:HBOR_RS05415
uniprot id: E4NQM4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

469382:HBOR RS11200
gene id: 469382:HBOR_RS11200
uniprot id: E4NQT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

469382:HBOR RS01170
gene id: 469382:HBOR_RS01170
uniprot id: E4NSW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

469382:HBOR RS09265
gene id: 469382:HBOR_RS09265
uniprot id: E4NNF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

469382:HBOR RS04790
gene id: 469382:HBOR_RS04790
uniprot id: E4NPV4
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

469382:HBOR RS07300
gene id: 469382:HBOR_RS07300
uniprot id: E4NTN4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

469382:HBOR RS06740
gene id: 469382:HBOR_RS06740
uniprot id: E4NSY5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469382:HBOR RS12240
gene id: 469382:HBOR_RS12240
uniprot id: L9UJK0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS15330
gene id: 469382:HBOR_RS15330
uniprot id: E4NUJ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS04695
gene id: 469382:HBOR_RS04695
uniprot id: E4NPT5
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS04905
gene id: 469382:HBOR_RS04905
uniprot id: E4NQ50
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS01065
gene id: 469382:HBOR_RS01065
uniprot id: E4NSU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

469382:HBOR RS07020
gene id: 469382:HBOR_RS07020
uniprot id: E4NT41
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS00815
gene id: 469382:HBOR_RS00815
uniprot id: E4NS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

469382:HBOR RS15650
gene id: 469382:HBOR_RS15650
uniprot id: L9ULN7
names: Caution
names: Similarity
messages: Belongs to the gas vesicle GvpA family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS11380
gene id: 469382:HBOR_RS11380
uniprot id: E4NQW8
names: Similarity
messages: Belongs to the DtxR/MntR family.

469382:HBOR RS09820
gene id: 469382:HBOR_RS09820
uniprot id: E4NP62
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

469382:HBOR RS02560
gene id: 469382:HBOR_RS02560
uniprot id: E4NM33
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

469382:HBOR RS08505
gene id: 469382:HBOR_RS08505
uniprot id: L9UUY6
names: Caution
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS18950
gene id: 469382:HBOR_RS18950
uniprot id: E4NWP1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS09295
gene id: 469382:HBOR_RS09295
uniprot id: E4NNF8
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

469382:HBOR RS05970
gene id: 469382:HBOR_RS05970
uniprot id: E4NR90
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS08585
gene id: 469382:HBOR_RS08585
uniprot id: E4NMT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

469382:HBOR RS11715
gene id: 469382:HBOR_RS11715
uniprot id: E4NRE2
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

469382:HBOR RS09795
gene id: 469382:HBOR_RS09795
uniprot id: E4NP57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

469382:HBOR RS08330
gene id: 469382:HBOR_RS08330
uniprot id: L9UUE9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS10845
gene id: 469382:HBOR_RS10845
uniprot id: E4NQD5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS11740
gene id: 469382:HBOR_RS11740
uniprot id: E4NRE7
names: Similarity
messages: Belongs to the TrpC family.

469382:HBOR RS05325
gene id: 469382:HBOR_RS05325
uniprot id: E4NQK5
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS00570
gene id: 469382:HBOR_RS00570
uniprot id: E4NS45
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

469382:HBOR RS16265
gene id: 469382:HBOR_RS16265
uniprot id: E4NVM3
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS04375
gene id: 469382:HBOR_RS04375
uniprot id: E4NPE8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS08170
gene id: 469382:HBOR_RS08170
uniprot id: E4NLQ8
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

469382:HBOR RS08895
gene id: 469382:HBOR_RS08895
uniprot id: E4NN03
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469382:HBOR RS10975
gene id: 469382:HBOR_RS10975
uniprot id: E4NQG1
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

469382:HBOR RS13160
gene id: 469382:HBOR_RS13160
uniprot id: E4NTW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS01605
gene id: 469382:HBOR_RS01605
uniprot id: E4NTJ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS04875
gene id: 469382:HBOR_RS04875
uniprot id: E4NQ44
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

469382:HBOR RS03740
gene id: 469382:HBOR_RS03740
uniprot id: L9V238
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS10870
gene id: 469382:HBOR_RS10870
uniprot id: E4NQE0
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS00840
gene id: 469382:HBOR_RS00840
uniprot id: E4NSA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

469382:HBOR RS04990
gene id: 469382:HBOR_RS04990
uniprot id: E4NQ65
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

469382:HBOR RS10395
gene id: 469382:HBOR_RS10395
uniprot id: E4NPX3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS11005
gene id: 469382:HBOR_RS11005
uniprot id: E4NQG8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

469382:HBOR RS12260
gene id: 469382:HBOR_RS12260
uniprot id: E4NSK1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS05830
gene id: 469382:HBOR_RS05830
uniprot id: E4NR62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

469382:HBOR RS08370
gene id: 469382:HBOR_RS08370
uniprot id: E4NM98
names: Function
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

469382:HBOR RS06925
gene id: 469382:HBOR_RS06925
uniprot id: E4NT23
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

469382:HBOR RS00100
gene id: 469382:HBOR_RS00100
uniprot id: E4NR10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

469382:HBOR RS04580
gene id: 469382:HBOR_RS04580
uniprot id: E4NPR1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS13375
gene id: 469382:HBOR_RS13375
uniprot id: E4NL64
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS17090
gene id: 469382:HBOR_RS17090
uniprot id: E4NV85
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS10095
gene id: 469382:HBOR_RS10095
uniprot id: L9UG10
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS18465
gene id: 469382:HBOR_RS18465
uniprot id: L9UQ04
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS18435
gene id: 469382:HBOR_RS18435
uniprot id: L9UNF9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS07905
gene id: 469382:HBOR_RS07905
uniprot id: E4NLK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS08875
gene id: 469382:HBOR_RS08875
uniprot id: E4NMZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

469382:HBOR RS00850
gene id: 469382:HBOR_RS00850
uniprot id: E4NSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

469382:HBOR RS10895
gene id: 469382:HBOR_RS10895
uniprot id: E4NQE5
uniprot id: L9UF04
names: Caution
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS18190
gene id: 469382:HBOR_RS18190
uniprot id: E4NW80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS02720
gene id: 469382:HBOR_RS02720
uniprot id: E4NMK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

469382:HBOR RS13250
gene id: 469382:HBOR_RS13250
uniprot id: E4NTY2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS01405
gene id: 469382:HBOR_RS01405
uniprot id: L9URU6
names: Caution
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS01330
gene id: 469382:HBOR_RS01330
uniprot id: E4NTE1
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS07580
gene id: 469382:HBOR_RS07580
uniprot id: E4NKY7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

469382:HBOR RS02470
gene id: 469382:HBOR_RS02470
uniprot id: E4NM15
names: Similarity
messages: Belongs to the AAA ATPase family.

469382:HBOR RS11725
gene id: 469382:HBOR_RS11725
uniprot id: E4NRE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

469382:HBOR RS12580
gene id: 469382:HBOR_RS12580
uniprot id: E4NT62
names: Similarity
messages: Belongs to the AOR/FOR family.

469382:HBOR RS15940
gene id: 469382:HBOR_RS15940
uniprot id: E4NVF6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

469382:HBOR RS16695
gene id: 469382:HBOR_RS16695
uniprot id: E4NV05
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

469382:HBOR RS06040
gene id: 469382:HBOR_RS06040
uniprot id: E4NRQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

469382:HBOR RS07470
gene id: 469382:HBOR_RS07470
uniprot id: E4NTR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

469382:HBOR RS05015
gene id: 469382:HBOR_RS05015
uniprot id: E4NQ70
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

469382:HBOR RS08385
gene id: 469382:HBOR_RS08385
uniprot id: E4NMA1
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.

469382:HBOR RS14795
gene id: 469382:HBOR_RS14795
uniprot id: E4NU82
names: Function
messages: Part of a potassium transport system.

469382:HBOR RS02505
gene id: 469382:HBOR_RS02505
uniprot id: E4NM22
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

469382:HBOR RS02295
gene id: 469382:HBOR_RS02295
uniprot id: E4NLI3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

469382:HBOR RS01180
gene id: 469382:HBOR_RS01180
uniprot id: E4NSW9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

469382:HBOR RS13965
gene id: 469382:HBOR_RS13965
uniprot id: E4NLY0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

469382:HBOR RS18170
gene id: 469382:HBOR_RS18170
uniprot id: E4NW76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

469382:HBOR RS15035
gene id: 469382:HBOR_RS15035
uniprot id: E4NUD3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS07945
gene id: 469382:HBOR_RS07945
uniprot id: E4NLL2
names: Subcellular Location Annotation
messages: Cytoplasm

469382:HBOR RS10025
gene id: 469382:HBOR_RS10025
uniprot id: E4NPA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

469382:HBOR RS00265
gene id: 469382:HBOR_RS00265
uniprot id: E4NRJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

469382:HBOR RS04015
gene id: 469382:HBOR_RS04015
uniprot id: E4NNZ7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

469382:HBOR RS13240
gene id: 469382:HBOR_RS13240
uniprot id: L9UKG0
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS09080
gene id: 469382:HBOR_RS09080
uniprot id: E4NNB4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS05820
gene id: 469382:HBOR_RS05820
uniprot id: E4NR60
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

469382:HBOR RS00660
gene id: 469382:HBOR_RS00660
uniprot id: E4NS65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

469382:HBOR RS01510
gene id: 469382:HBOR_RS01510
uniprot id: E4NTH7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

469382:HBOR RS15125
gene id: 469382:HBOR_RS15125
uniprot id: E4NUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the halobacterial S-layer protein family.
messages: Cell membrane
messages: Membrane
messages: S-layer

469382:HBOR RS05320
gene id: 469382:HBOR_RS05320
uniprot id: E4NQK4
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS11115
gene id: 469382:HBOR_RS11115
uniprot id: E4NQR6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

469382:HBOR RS02915
gene id: 469382:HBOR_RS02915
uniprot id: E4NMP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

469382:HBOR RS08750
gene id: 469382:HBOR_RS08750
uniprot id: E4NMX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

469382:HBOR RS09465
gene id: 469382:HBOR_RS09465
uniprot id: E4NNR7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

469382:HBOR RS00275
gene id: 469382:HBOR_RS00275
uniprot id: E4NRJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

469382:HBOR RS07460
gene id: 469382:HBOR_RS07460
uniprot id: E4NTR4
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.

469382:HBOR RS13295
gene id: 469382:HBOR_RS13295
uniprot id: E4NL47
names: Similarity
messages: Belongs to the UPF0215 family.

469382:HBOR RS12245
gene id: 469382:HBOR_RS12245
uniprot id: E4NSJ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

469382:HBOR RS13630
gene id: 469382:HBOR_RS13630
uniprot id: E4NLB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

469382:HBOR RS05980
gene id: 469382:HBOR_RS05980
uniprot id: E4NR92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

469382:HBOR RS01050
gene id: 469382:HBOR_RS01050
uniprot id: E4NSU3
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

469382:HBOR RS04595
gene id: 469382:HBOR_RS04595
uniprot id: E4NPR5
names: Similarity
messages: Belongs to the PEPCase type 1 family.

469382:HBOR RS05655
gene id: 469382:HBOR_RS05655
uniprot id: L9UZ86
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS00585
gene id: 469382:HBOR_RS00585
uniprot id: E4NS48
names: Similarity
messages: Belongs to the UPF0175 family.

469382:HBOR RS16955
gene id: 469382:HBOR_RS16955
uniprot id: E4NV58
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS01465
gene id: 469382:HBOR_RS01465
uniprot id: E4NTG8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

469382:HBOR RS07680
gene id: 469382:HBOR_RS07680
uniprot id: E4NL07
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

469382:HBOR RS09085
gene id: 469382:HBOR_RS09085
uniprot id: E4NNB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

469382:HBOR RS06245
gene id: 469382:HBOR_RS06245
uniprot id: E4NRU0
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

469382:HBOR RS16475
gene id: 469382:HBOR_RS16475
uniprot id: E4NUW0
names: Similarity
messages: Belongs to the citrate synthase family.

469382:HBOR RS17410
gene id: 469382:HBOR_RS17410
uniprot id: E4NVS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

469382:HBOR RS13860
gene id: 469382:HBOR_RS13860
uniprot id: E4NLV9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

469382:HBOR RS14770
gene id: 469382:HBOR_RS14770
uniprot id: E4NU75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

469382:HBOR RS05285
gene id: 469382:HBOR_RS05285
uniprot id: E4NQJ6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469382:HBOR RS17470
gene id: 469382:HBOR_RS17470
uniprot id: E4NVT3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469382:HBOR RS08540
gene id: 469382:HBOR_RS08540
uniprot id: E4NMD3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

469382:HBOR RS09995
gene id: 469382:HBOR_RS09995
uniprot id: E4NP98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

469382:HBOR RS00160
gene id: 469382:HBOR_RS00160
uniprot id: E4NRH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

469382:HBOR RS05885
gene id: 469382:HBOR_RS05885
uniprot id: L9UZX8
names: Caution
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS13740
gene id: 469382:HBOR_RS13740
uniprot id: E4NLT4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

469382:HBOR RS12570
gene id: 469382:HBOR_RS12570
uniprot id: E4NT60
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

469382:HBOR RS12065
gene id: 469382:HBOR_RS12065
uniprot id: E4NS08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

469382:HBOR RS18500
gene id: 469382:HBOR_RS18500
uniprot id: E4NWE7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

469382:HBOR RS09285
gene id: 469382:HBOR_RS09285
uniprot id: L9UG24
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS07320
gene id: 469382:HBOR_RS07320
uniprot id: L9UY48
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS00185
gene id: 469382:HBOR_RS00185
uniprot id: E4NRH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

469382:HBOR RS03110
gene id: 469382:HBOR_RS03110
uniprot id: E4NN14
names: Similarity
messages: Belongs to the thymidylate kinase family.

469382:HBOR RS17205
gene id: 469382:HBOR_RS17205
uniprot id: L9UWU7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS20260
gene id: 469382:HBOR_RS20260
uniprot id: L9USL3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS16015
gene id: 469382:HBOR_RS16015
uniprot id: L9UVE1
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14945
gene id: 469382:HBOR_RS14945
uniprot id: E4NUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS16185
gene id: 469382:HBOR_RS16185
uniprot id: E4NVK5
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS03610
gene id: 469382:HBOR_RS03610
uniprot id: E4NNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

469382:HBOR RS04575
gene id: 469382:HBOR_RS04575
uniprot id: E4NPR0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

469382:HBOR RS08160
gene id: 469382:HBOR_RS08160
uniprot id: E4NLQ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

469382:HBOR RS14235
gene id: 469382:HBOR_RS14235
uniprot id: E4NMI7
names: Similarity
messages: Belongs to the threonine aldolase family.

469382:HBOR RS11730
gene id: 469382:HBOR_RS11730
uniprot id: E4NRE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

469382:HBOR RS11495
gene id: 469382:HBOR_RS11495
uniprot id: L9UHN4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS20025
gene id: 469382:HBOR_RS20025
uniprot id: L9UHK8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS08250
gene id: 469382:HBOR_RS08250
uniprot id: E4NM73
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS06680
gene id: 469382:HBOR_RS06680
uniprot id: E4NSH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

469382:HBOR RS13360
gene id: 469382:HBOR_RS13360
uniprot id: E4NL61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

469382:HBOR RS12335
gene id: 469382:HBOR_RS12335
uniprot id: E4NSL6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

469382:HBOR RS09235
gene id: 469382:HBOR_RS09235
uniprot id: E4NNE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469382:HBOR RS08945
gene id: 469382:HBOR_RS08945
uniprot id: E4NN87
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

469382:HBOR RS06210
gene id: 469382:HBOR_RS06210
uniprot id: E4NRT3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS10820
gene id: 469382:HBOR_RS10820
uniprot id: E4NQD0
names: Function
messages: Part of a potassium transport system.

469382:HBOR RS06820
gene id: 469382:HBOR_RS06820
uniprot id: E4NT00
names: Similarity
messages: Belongs to the Nth/MutY family.

469382:HBOR RS10915
gene id: 469382:HBOR_RS10915
uniprot id: E4NQE9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS09190
gene id: 469382:HBOR_RS09190
uniprot id: E4NND7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

469382:HBOR RS05870
gene id: 469382:HBOR_RS05870
uniprot id: E4NR70
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

469382:HBOR RS12185
gene id: 469382:HBOR_RS12185
uniprot id: E4NS33
names: Subunit
messages: Homodimer.

469382:HBOR RS13595
gene id: 469382:HBOR_RS13595
uniprot id: E4NLA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

469382:HBOR RS10800
gene id: 469382:HBOR_RS10800
uniprot id: E4NQC6
names: Function
messages: Part of a potassium transport system.

469382:HBOR RS09735
gene id: 469382:HBOR_RS09735
uniprot id: E4NP45
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

469382:HBOR RS01120
gene id: 469382:HBOR_RS01120
uniprot id: E4NSV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

469382:HBOR RS11505
gene id: 469382:HBOR_RS11505
uniprot id: E4NRA0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

469382:HBOR RS00785
gene id: 469382:HBOR_RS00785
uniprot id: E4NS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

469382:HBOR RS14205
gene id: 469382:HBOR_RS14205
uniprot id: E4NMI1
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS18750
gene id: 469382:HBOR_RS18750
uniprot id: E4NWJ8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

469382:HBOR RS13625
gene id: 469382:HBOR_RS13625
uniprot id: E4NLB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

469382:HBOR RS13865
gene id: 469382:HBOR_RS13865
uniprot id: E4NLW0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

469382:HBOR RS03275
gene id: 469382:HBOR_RS03275
uniprot id: L9UU88
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS18665
gene id: 469382:HBOR_RS18665
uniprot id: E4NWI1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

469382:HBOR RS05250
gene id: 469382:HBOR_RS05250
uniprot id: E4NQB5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

469382:HBOR RS07200
gene id: 469382:HBOR_RS07200
uniprot id: E4NTL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

469382:HBOR RS17925
gene id: 469382:HBOR_RS17925
uniprot id: E4NW25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS10145
gene id: 469382:HBOR_RS10145
uniprot id: E4NPJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS04970
gene id: 469382:HBOR_RS04970
uniprot id: E4NQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

469382:HBOR RS09355
gene id: 469382:HBOR_RS09355
uniprot id: E4NNP5
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

469382:HBOR RS01060
gene id: 469382:HBOR_RS01060
uniprot id: E4NSU4
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

469382:HBOR RS09850
gene id: 469382:HBOR_RS09850
uniprot id: E4NP68
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469382:HBOR RS13070
gene id: 469382:HBOR_RS13070
uniprot id: E4NTU7
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

469382:HBOR RS07430
gene id: 469382:HBOR_RS07430
uniprot id: L9UY47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14265
gene id: 469382:HBOR_RS14265
uniprot id: E4NMJ4
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS07835
gene id: 469382:HBOR_RS07835
uniprot id: E4NL39
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

469382:HBOR RS03100
gene id: 469382:HBOR_RS03100
uniprot id: E4NN12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

469382:HBOR RS18050
gene id: 469382:HBOR_RS18050
uniprot id: L9V425
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS02410
gene id: 469382:HBOR_RS02410
uniprot id: E4NM02
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

469382:HBOR RS18060
gene id: 469382:HBOR_RS18060
uniprot id: E4NW53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

469382:HBOR RS18515
gene id: 469382:HBOR_RS18515
uniprot id: E4NWF0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

469382:HBOR RS05905
gene id: 469382:HBOR_RS05905
uniprot id: E4NR77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

469382:HBOR RS11690
gene id: 469382:HBOR_RS11690
uniprot id: E4NRD7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

469382:HBOR RS18960
gene id: 469382:HBOR_RS18960
uniprot id: E4NWP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS18805
gene id: 469382:HBOR_RS18805
uniprot id: E4NWL0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

469382:HBOR RS05935
gene id: 469382:HBOR_RS05935
uniprot id: E4NR83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Homodimer.

469382:HBOR RS03535
gene id: 469382:HBOR_RS03535
uniprot id: E4NNH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

469382:HBOR RS12190
gene id: 469382:HBOR_RS12190
uniprot id: E4NSI7
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS17465
gene id: 469382:HBOR_RS17465
uniprot id: E4NVT2
names: Similarity
messages: Belongs to the glutamine synthetase family.

469382:HBOR RS08840
gene id: 469382:HBOR_RS08840
uniprot id: E4NMZ0
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS04975
gene id: 469382:HBOR_RS04975
uniprot id: E4NQ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

469382:HBOR RS08255
gene id: 469382:HBOR_RS08255
uniprot id: E4NM74
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS08600
gene id: 469382:HBOR_RS08600
uniprot id: E4NMU1
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

469382:HBOR RS13580
gene id: 469382:HBOR_RS13580
uniprot id: E4NLA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

469382:HBOR RS16525
gene id: 469382:HBOR_RS16525
uniprot id: E4NUX0
names: Cofactor
messages: Binds 1 copper ion per subunit.

469382:HBOR RS02900
gene id: 469382:HBOR_RS02900
uniprot id: L9URH2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS08365
gene id: 469382:HBOR_RS08365
uniprot id: E4NM97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

469382:HBOR RS00070
gene id: 469382:HBOR_RS00070
uniprot id: E4NR02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

469382:HBOR RS11585
gene id: 469382:HBOR_RS11585
uniprot id: E4NRB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

469382:HBOR RS02760
gene id: 469382:HBOR_RS02760
uniprot id: E4NML7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

469382:HBOR RS15790
gene id: 469382:HBOR_RS15790
uniprot id: E4NUT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS09785
gene id: 469382:HBOR_RS09785
uniprot id: E4NP55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

469382:HBOR RS16565
gene id: 469382:HBOR_RS16565
uniprot id: E4NUX9
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

469382:HBOR RS05005
gene id: 469382:HBOR_RS05005
uniprot id: E4NQ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

469382:HBOR RS17565
gene id: 469382:HBOR_RS17565
uniprot id: E4NVV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS04080
gene id: 469382:HBOR_RS04080
uniprot id: E4NP11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

469382:HBOR RS06020
gene id: 469382:HBOR_RS06020
uniprot id: E4NRP9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

469382:HBOR RS07860
gene id: 469382:HBOR_RS07860
uniprot id: E4NLJ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

469382:HBOR RS04350
gene id: 469382:HBOR_RS04350
uniprot id: E4NPE3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

469382:HBOR RS08120
gene id: 469382:HBOR_RS08120
uniprot id: E4NLP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

469382:HBOR RS01480
gene id: 469382:HBOR_RS01480
uniprot id: E4NTH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

469382:HBOR RS15000
gene id: 469382:HBOR_RS15000
uniprot id: E4NUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS07605
gene id: 469382:HBOR_RS07605
uniprot id: E4NKZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

469382:HBOR RS12915
gene id: 469382:HBOR_RS12915
uniprot id: L9UID7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS01890
gene id: 469382:HBOR_RS01890
uniprot id: E4NKV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS07135
gene id: 469382:HBOR_RS07135
uniprot id: L9UXE8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS12290
gene id: 469382:HBOR_RS12290
uniprot id: E4NSK7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS04475
gene id: 469382:HBOR_RS04475
uniprot id: E4NPG8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS02520
gene id: 469382:HBOR_RS02520
uniprot id: E4NM25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS00905
gene id: 469382:HBOR_RS00905
uniprot id: L9UPZ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS18000
gene id: 469382:HBOR_RS18000
uniprot id: E4NW41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

469382:HBOR RS02190
gene id: 469382:HBOR_RS02190
uniprot id: E4NLG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

469382:HBOR RS07970
gene id: 469382:HBOR_RS07970
uniprot id: E4NLL6
names: Similarity
messages: Belongs to the arginase family.

469382:HBOR RS14890
gene id: 469382:HBOR_RS14890
uniprot id: E4NUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

469382:HBOR RS14525
gene id: 469382:HBOR_RS14525
uniprot id: E4NU25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS03545
gene id: 469382:HBOR_RS03545
uniprot id: E4NNH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

469382:HBOR RS16085
gene id: 469382:HBOR_RS16085
uniprot id: E4NVI5
names: Similarity
messages: Belongs to the RutC family.

469382:HBOR RS07855
gene id: 469382:HBOR_RS07855
uniprot id: E4NLJ2
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

469382:HBOR RS18395
gene id: 469382:HBOR_RS18395
uniprot id: E4NWC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS00755
gene id: 469382:HBOR_RS00755
uniprot id: E4NS84
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

469382:HBOR RS12955
gene id: 469382:HBOR_RS12955
uniprot id: E4NTS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

469382:HBOR RS10235
gene id: 469382:HBOR_RS10235
uniprot id: E4NPL5
names: Subcellular Location Annotation
messages: Cytoplasm

469382:HBOR RS13080
gene id: 469382:HBOR_RS13080
uniprot id: E4NTU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

469382:HBOR RS07815
gene id: 469382:HBOR_RS07815
uniprot id: E4NL35
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

469382:HBOR RS09165
gene id: 469382:HBOR_RS09165
uniprot id: E4NND2
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

469382:HBOR RS10785
gene id: 469382:HBOR_RS10785
uniprot id: E4NQC3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

469382:HBOR RS14240
gene id: 469382:HBOR_RS14240
uniprot id: E4NMI8
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS16355
gene id: 469382:HBOR_RS16355
uniprot id: L9UW08
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS05930
gene id: 469382:HBOR_RS05930
uniprot id: L9V002
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS07975
gene id: 469382:HBOR_RS07975
uniprot id: E4NLL7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

469382:HBOR RS11945
gene id: 469382:HBOR_RS11945
uniprot id: E4NRY3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

469382:HBOR RS09340
gene id: 469382:HBOR_RS09340
uniprot id: E4NNP2
names: Similarity
messages: Belongs to the peptidase C56 family.

469382:HBOR RS00405
gene id: 469382:HBOR_RS00405
uniprot id: E4NRM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

469382:HBOR RS08055
gene id: 469382:HBOR_RS08055
uniprot id: E4NLN3
names: Similarity
messages: Belongs to the UPF0212 family.

469382:HBOR RS17450
gene id: 469382:HBOR_RS17450
uniprot id: E4NVS9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS12340
gene id: 469382:HBOR_RS12340
uniprot id: E4NSL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

469382:HBOR RS12345
gene id: 469382:HBOR_RS12345
uniprot id: E4NSL8
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

469382:HBOR RS05915
gene id: 469382:HBOR_RS05915
uniprot id: E4NR79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

469382:HBOR RS11705
gene id: 469382:HBOR_RS11705
uniprot id: E4NRE0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS10545
gene id: 469382:HBOR_RS10545
uniprot id: E4NQ03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS19020
gene id: 469382:HBOR_RS19020
uniprot id: E4NWQ6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

469382:HBOR RS11110
gene id: 469382:HBOR_RS11110
uniprot id: E4NQI9
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

469382:HBOR RS08075
gene id: 469382:HBOR_RS08075
uniprot id: E4NLN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

469382:HBOR RS01210
gene id: 469382:HBOR_RS01210
uniprot id: E4NSX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

469382:HBOR RS05610
gene id: 469382:HBOR_RS05610
uniprot id: E4NQR4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS12755
gene id: 469382:HBOR_RS12755
uniprot id: E4NT97
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

469382:HBOR RS04250
gene id: 469382:HBOR_RS04250
uniprot id: E4NPC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

469382:HBOR RS02030
gene id: 469382:HBOR_RS02030
uniprot id: L9URI4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS01710
gene id: 469382:HBOR_RS01710
uniprot id: E4NKR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

469382:HBOR RS07290
gene id: 469382:HBOR_RS07290
uniprot id: L9UXH0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS00555
gene id: 469382:HBOR_RS00555
uniprot id: E4NS42
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

469382:HBOR RS18685
gene id: 469382:HBOR_RS18685
uniprot id: E4NWI5
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS16505
gene id: 469382:HBOR_RS16505
uniprot id: L9UWJ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS11055
gene id: 469382:HBOR_RS11055
uniprot id: E4NQH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

469382:HBOR RS19000
gene id: 469382:HBOR_RS19000
uniprot id: E4NWQ1
names: Similarity
messages: Belongs to the Dps family.

469382:HBOR RS16740
gene id: 469382:HBOR_RS16740
uniprot id: E4NV14
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS02940
gene id: 469382:HBOR_RS02940
uniprot id: E4NMQ2
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

469382:HBOR RS08995
gene id: 469382:HBOR_RS08995
uniprot id: E4NN97
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

469382:HBOR RS13855
gene id: 469382:HBOR_RS13855
uniprot id: L9V2D8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14730
gene id: 469382:HBOR_RS14730
uniprot id: E4NU67
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

469382:HBOR RS13320
gene id: 469382:HBOR_RS13320
uniprot id: E4NL53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

469382:HBOR RS16885
gene id: 469382:HBOR_RS16885
uniprot id: E4NV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS03525
gene id: 469382:HBOR_RS03525
uniprot id: E4NNH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS13615
gene id: 469382:HBOR_RS13615
uniprot id: E4NLB2
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

469382:HBOR RS00010
gene id: 469382:HBOR_RS00010
uniprot id: L9USK0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS02450
gene id: 469382:HBOR_RS02450
uniprot id: L9UR53
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS09290
gene id: 469382:HBOR_RS09290
uniprot id: E4NNF7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

469382:HBOR RS06215
gene id: 469382:HBOR_RS06215
uniprot id: E4NRT4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

469382:HBOR RS06090
gene id: 469382:HBOR_RS06090
uniprot id: E4NRR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

469382:HBOR RS01895
gene id: 469382:HBOR_RS01895
uniprot id: E4NKV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS12160
gene id: 469382:HBOR_RS12160
uniprot id: E4NS26
names: Similarity
messages: Belongs to the eIF-2-alpha family.

469382:HBOR RS03890
gene id: 469382:HBOR_RS03890
uniprot id: L9V447
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14285
gene id: 469382:HBOR_RS14285
uniprot id: E4NMJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS06055
gene id: 469382:HBOR_RS06055
uniprot id: E4NRQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

469382:HBOR RS15685
gene id: 469382:HBOR_RS15685
uniprot id: E4NUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

469382:HBOR RS07715
gene id: 469382:HBOR_RS07715
uniprot id: E4NL14
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

469382:HBOR RS08285
gene id: 469382:HBOR_RS08285
uniprot id: E4NM81
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS07405
gene id: 469382:HBOR_RS07405
uniprot id: E4NTQ4
names: Similarity
messages: Belongs to the UPF0212 family.

469382:HBOR RS07760
gene id: 469382:HBOR_RS07760
uniprot id: E4NL23
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

469382:HBOR RS04945
gene id: 469382:HBOR_RS04945
uniprot id: E4NQ56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

469382:HBOR RS08175
gene id: 469382:HBOR_RS08175
uniprot id: E4NLQ9
names: Similarity
messages: Belongs to the CutA family.

469382:HBOR RS17105
gene id: 469382:HBOR_RS17105
uniprot id: E4NV87
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

469382:HBOR RS15720
gene id: 469382:HBOR_RS15720
uniprot id: E4NUS5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

469382:HBOR RS12880
gene id: 469382:HBOR_RS12880
uniprot id: E4NTC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

469382:HBOR RS04950
gene id: 469382:HBOR_RS04950
uniprot id: E4NQ57
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

469382:HBOR RS00115
gene id: 469382:HBOR_RS00115
uniprot id: E4NR13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

469382:HBOR RS06085
gene id: 469382:HBOR_RS06085
uniprot id: E4NRR0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS15385
gene id: 469382:HBOR_RS15385
uniprot id: E4NUK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS12630
gene id: 469382:HBOR_RS12630
uniprot id: E4NT72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

469382:HBOR RS00435
gene id: 469382:HBOR_RS00435
uniprot id: L9USA2
names: Caution
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14695
gene id: 469382:HBOR_RS14695
uniprot id: E4NU60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

469382:HBOR RS14950
gene id: 469382:HBOR_RS14950
uniprot id: E4NUB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS14230
gene id: 469382:HBOR_RS14230
uniprot id: E4NMI6
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS18755
gene id: 469382:HBOR_RS18755
uniprot id: E4NWJ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469382:HBOR RS10315
gene id: 469382:HBOR_RS10315
uniprot id: E4NPN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

469382:HBOR RS04425
gene id: 469382:HBOR_RS04425
uniprot id: E4NPF8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469382:HBOR RS09695
gene id: 469382:HBOR_RS09695
uniprot id: E4NP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

469382:HBOR RS09710
gene id: 469382:HBOR_RS09710
uniprot id: E4NP40
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS17695
gene id: 469382:HBOR_RS17695
uniprot id: E4NVX6
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

469382:HBOR RS12615
gene id: 469382:HBOR_RS12615
uniprot id: E4NT69
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

469382:HBOR RS07935
gene id: 469382:HBOR_RS07935
uniprot id: E4NLL0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

469382:HBOR RS02730
gene id: 469382:HBOR_RS02730
uniprot id: E4NML1
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS00280
gene id: 469382:HBOR_RS00280
uniprot id: E4NRJ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

469382:HBOR RS03900
gene id: 469382:HBOR_RS03900
uniprot id: E4NNX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

469382:HBOR RS10190
gene id: 469382:HBOR_RS10190
uniprot id: E4NPK6
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.

469382:HBOR RS00765
gene id: 469382:HBOR_RS00765
uniprot id: E4NS86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

469382:HBOR RS04840
gene id: 469382:HBOR_RS04840
uniprot id: E4NPW5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

469382:HBOR RS13370
gene id: 469382:HBOR_RS13370
uniprot id: E4NL63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

469382:HBOR RS10500
gene id: 469382:HBOR_RS10500
uniprot id: E4NPZ3
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS08200
gene id: 469382:HBOR_RS08200
uniprot id: E4NLR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

469382:HBOR RS00495
gene id: 469382:HBOR_RS00495
uniprot id: L9UQB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS03230
gene id: 469382:HBOR_RS03230
uniprot id: E4NN38
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

469382:HBOR RS17795
gene id: 469382:HBOR_RS17795
uniprot id: E4NVZ8
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS12835
gene id: 469382:HBOR_RS12835
uniprot id: E4NTB3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

469382:HBOR RS00500
gene id: 469382:HBOR_RS00500
uniprot id: E4NRP0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

469382:HBOR RS00645
gene id: 469382:HBOR_RS00645
uniprot id: E4NS62
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS18955
gene id: 469382:HBOR_RS18955
uniprot id: E4NWP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS11580
gene id: 469382:HBOR_RS11580
uniprot id: E4NRB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

469382:HBOR RS01015
gene id: 469382:HBOR_RS01015
uniprot id: E4NST6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

469382:HBOR RS08035
gene id: 469382:HBOR_RS08035
uniprot id: E4NLM9
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

469382:HBOR RS03425
gene id: 469382:HBOR_RS03425
uniprot id: E4NN79
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

469382:HBOR RS01720
gene id: 469382:HBOR_RS01720
uniprot id: E4NKR3
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS04210
gene id: 469382:HBOR_RS04210
uniprot id: E4NPB5
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

469382:HBOR RS15655
gene id: 469382:HBOR_RS15655
uniprot id: E4NUR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

469382:HBOR RS05920
gene id: 469382:HBOR_RS05920
uniprot id: E4NR80
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

469382:HBOR RS13190
gene id: 469382:HBOR_RS13190
uniprot id: E4NTX0
names: Similarity
messages: Belongs to the citrate synthase family.

469382:HBOR RS17065
gene id: 469382:HBOR_RS17065
uniprot id: E4NV80
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

469382:HBOR RS14615
gene id: 469382:HBOR_RS14615
uniprot id: E4NU44
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS16895
gene id: 469382:HBOR_RS16895
uniprot id: E4NV46
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS06905
gene id: 469382:HBOR_RS06905
uniprot id: E4NT19
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

469382:HBOR RS07880
gene id: 469382:HBOR_RS07880
uniprot id: E4NLJ9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

469382:HBOR RS05000
gene id: 469382:HBOR_RS05000
uniprot id: E4NQ67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

469382:HBOR RS15020
gene id: 469382:HBOR_RS15020
uniprot id: E4NUC8
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS14510
gene id: 469382:HBOR_RS14510
uniprot id: E4NU22
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS12800
gene id: 469382:HBOR_RS12800
uniprot id: E4NTA6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

469382:HBOR RS04640
gene id: 469382:HBOR_RS04640
uniprot id: E4NPS4
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

469382:HBOR RS05660
gene id: 469382:HBOR_RS05660
uniprot id: E4NR27
names: Similarity
messages: Belongs to the archease family.

469382:HBOR RS11095
gene id: 469382:HBOR_RS11095
uniprot id: E4NQI6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

469382:HBOR RS04185
gene id: 469382:HBOR_RS04185
uniprot id: E4NPA9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS12585
gene id: 469382:HBOR_RS12585
uniprot id: E4NT63
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS01445
gene id: 469382:HBOR_RS01445
uniprot id: E4NTG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

469382:HBOR RS11810
gene id: 469382:HBOR_RS11810
uniprot id: L9UHA1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS03975
gene id: 469382:HBOR_RS03975
uniprot id: E4NNY9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

469382:HBOR RS02220
gene id: 469382:HBOR_RS02220
uniprot id: L9URA6
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS13205
gene id: 469382:HBOR_RS13205
uniprot id: E4NTX3
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS14570
gene id: 469382:HBOR_RS14570
uniprot id: E4NU34
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469382:HBOR RS10780
gene id: 469382:HBOR_RS10780
uniprot id: E4NQC2
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

469382:HBOR RS05025
gene id: 469382:HBOR_RS05025
uniprot id: E4NQ72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

469382:HBOR RS09095
gene id: 469382:HBOR_RS09095
uniprot id: E4NNB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

469382:HBOR RS00640
gene id: 469382:HBOR_RS00640
uniprot id: E4NS61
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

469382:HBOR RS02815
gene id: 469382:HBOR_RS02815
uniprot id: E4NMM8
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS03930
gene id: 469382:HBOR_RS03930
uniprot id: E4NNY0
names: Similarity
messages: Belongs to the LarC family.

469382:HBOR RS17330
gene id: 469382:HBOR_RS17330
uniprot id: E4NVQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS04940
gene id: 469382:HBOR_RS04940
uniprot id: E4NQ55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

469382:HBOR RS17600
gene id: 469382:HBOR_RS17600
uniprot id: L9V5T7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS06575
gene id: 469382:HBOR_RS06575
uniprot id: E4NSF5
names: Similarity
messages: Belongs to the UPF0179 family.

469382:HBOR RS05740
gene id: 469382:HBOR_RS05740
uniprot id: E4NR42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

469382:HBOR RS10700
gene id: 469382:HBOR_RS10700
uniprot id: L9UFD0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS02675
gene id: 469382:HBOR_RS02675
uniprot id: E4NM56
names: Similarity
messages: Belongs to the PdaD family.

469382:HBOR RS12195
gene id: 469382:HBOR_RS12195
uniprot id: E4NSI8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

469382:HBOR RS15375
gene id: 469382:HBOR_RS15375
uniprot id: E4NUK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

469382:HBOR RS16480
gene id: 469382:HBOR_RS16480
uniprot id: E4NUW1
names: Subunit
messages: Homotrimer.

469382:HBOR RS18880
gene id: 469382:HBOR_RS18880
uniprot id: L9UMC5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS16830
gene id: 469382:HBOR_RS16830
uniprot id: E4NV33
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS05305
gene id: 469382:HBOR_RS05305
uniprot id: E4NQK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

469382:HBOR RS18910
gene id: 469382:HBOR_RS18910
uniprot id: E4NWN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS18115
gene id: 469382:HBOR_RS18115
uniprot id: E4NW65
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS07160
gene id: 469382:HBOR_RS07160
uniprot id: E4NTK6
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS12125
gene id: 469382:HBOR_RS12125
uniprot id: E4NS19
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS08070
gene id: 469382:HBOR_RS08070
uniprot id: E4NLN6
names: Similarity
messages: Belongs to the cytochrome P450 family.

469382:HBOR RS12785
gene id: 469382:HBOR_RS12785
uniprot id: E4NTA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS05665
gene id: 469382:HBOR_RS05665
uniprot id: E4NR28
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS08225
gene id: 469382:HBOR_RS08225
uniprot id: E4NM68
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS15420
gene id: 469382:HBOR_RS15420
uniprot id: E4NUL6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS09040
gene id: 469382:HBOR_RS09040
uniprot id: E4NNA6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

469382:HBOR RS09330
gene id: 469382:HBOR_RS09330
uniprot id: L9UFT1
names: Caution
names: Similarity
messages: Belongs to the UPF0173 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS08735
gene id: 469382:HBOR_RS08735
uniprot id: E4NMW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS06145
gene id: 469382:HBOR_RS06145
uniprot id: E4NRS1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS03430
gene id: 469382:HBOR_RS03430
uniprot id: L9USL6
names: Caution
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS16675
gene id: 469382:HBOR_RS16675
uniprot id: E4NV01
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

469382:HBOR RS01305
gene id: 469382:HBOR_RS01305
uniprot id: E4NTD6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

469382:HBOR RS10705
gene id: 469382:HBOR_RS10705
uniprot id: L9UH54
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS00830
gene id: 469382:HBOR_RS00830
uniprot id: E4NSA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS02230
gene id: 469382:HBOR_RS02230
uniprot id: E4NLH0
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS15510
gene id: 469382:HBOR_RS15510
uniprot id: E4NUN2
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS20180
gene id: 469382:HBOR_RS20180
uniprot id: L9UUW9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS11555
gene id: 469382:HBOR_RS11555
uniprot id: E4NRB0
names: Cofactor
messages: The crystal structure with reduced Cu(1+) has also been determined.

469382:HBOR RS10130
gene id: 469382:HBOR_RS10130
uniprot id: L9UFC2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14300
gene id: 469382:HBOR_RS14300
uniprot id: E4NMK1
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS03440
gene id: 469382:HBOR_RS03440
uniprot id: E4NN82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

469382:HBOR RS08820
gene id: 469382:HBOR_RS08820
uniprot id: E4NMY6
names: Similarity
messages: Belongs to the acylphosphatase family.

469382:HBOR RS05575
gene id: 469382:HBOR_RS05575
uniprot id: E4NQQ7
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

469382:HBOR RS16735
gene id: 469382:HBOR_RS16735
uniprot id: E4NV13
names: Subcellular Location Annotation
messages: Cytoplasm

469382:HBOR RS03030
gene id: 469382:HBOR_RS03030
uniprot id: E4NMS3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

469382:HBOR RS12060
gene id: 469382:HBOR_RS12060
uniprot id: L9UJI0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS04750
gene id: 469382:HBOR_RS04750
uniprot id: L9V0Y7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14780
gene id: 469382:HBOR_RS14780
uniprot id: E4NU79
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

469382:HBOR RS01600
gene id: 469382:HBOR_RS01600
uniprot id: E4NTJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS07980
gene id: 469382:HBOR_RS07980
uniprot id: E4NLL8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

469382:HBOR RS04675
gene id: 469382:HBOR_RS04675
uniprot id: E4NPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

469382:HBOR RS02555
gene id: 469382:HBOR_RS02555
uniprot id: E4NM32
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

469382:HBOR RS16720
gene id: 469382:HBOR_RS16720
uniprot id: E4NV10
names: Similarity
messages: Belongs to the peptidase S8 family.

469382:HBOR RS15135
gene id: 469382:HBOR_RS15135
uniprot id: E4NUF4
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS00470
gene id: 469382:HBOR_RS00470
uniprot id: E4NRN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

469382:HBOR RS03035
gene id: 469382:HBOR_RS03035
uniprot id: L9URE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS13215
gene id: 469382:HBOR_RS13215
uniprot id: E4NTX5
names: Similarity
messages: Belongs to the RutC family.

469382:HBOR RS08975
gene id: 469382:HBOR_RS08975
uniprot id: L9UEI7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS00810
gene id: 469382:HBOR_RS00810
uniprot id: E4NS96
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS11795
gene id: 469382:HBOR_RS11795
uniprot id: L9UGL1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS10005
gene id: 469382:HBOR_RS10005
uniprot id: E4NPA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

469382:HBOR RS10575
gene id: 469382:HBOR_RS10575
uniprot id: E4NQ09
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

469382:HBOR RS13290
gene id: 469382:HBOR_RS13290
uniprot id: E4NL46
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

469382:HBOR RS13235
gene id: 469382:HBOR_RS13235
uniprot id: L9UIF9
names: Caution
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14595
gene id: 469382:HBOR_RS14595
uniprot id: E4NU39
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469382:HBOR RS10020
gene id: 469382:HBOR_RS10020
uniprot id: E4NPA3
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS00205
gene id: 469382:HBOR_RS00205
uniprot id: L9US48
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS07745
gene id: 469382:HBOR_RS07745
uniprot id: E4NL20
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS06060
gene id: 469382:HBOR_RS06060
uniprot id: E4NRQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

469382:HBOR RS17110
gene id: 469382:HBOR_RS17110
uniprot id: E4NV88
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

469382:HBOR RS05115
gene id: 469382:HBOR_RS05115
uniprot id: E4NQ90
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

469382:HBOR RS02040
gene id: 469382:HBOR_RS02040
uniprot id: E4NLD0
names: Cofactor
messages: The crystal structure with reduced Cu(1+) has also been determined.

469382:HBOR RS14590
gene id: 469382:HBOR_RS14590
uniprot id: E4NU38
names: Similarity
messages: Belongs to the leucine-binding protein family.

469382:HBOR RS05515
gene id: 469382:HBOR_RS05515
uniprot id: E4NQP4
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

469382:HBOR RS01815
gene id: 469382:HBOR_RS01815
uniprot id: E4NKT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
messages: Homotetramer.

469382:HBOR RS18780
gene id: 469382:HBOR_RS18780
uniprot id: E4NWK4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469382:HBOR RS08535
gene id: 469382:HBOR_RS08535
uniprot id: E4NMD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

469382:HBOR RS14255
gene id: 469382:HBOR_RS14255
uniprot id: E4NMJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

469382:HBOR RS12945
gene id: 469382:HBOR_RS12945
uniprot id: E4NTS5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

469382:HBOR RS09870
gene id: 469382:HBOR_RS09870
uniprot id: E4NP72
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS14940
gene id: 469382:HBOR_RS14940
uniprot id: E4NUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS01145
gene id: 469382:HBOR_RS01145
uniprot id: E4NSW2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS05690
gene id: 469382:HBOR_RS05690
uniprot id: E4NR33
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469382:HBOR RS01495
gene id: 469382:HBOR_RS01495
uniprot id: E4NTH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

469382:HBOR RS15440
gene id: 469382:HBOR_RS15440
uniprot id: L9UKT0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS13415
gene id: 469382:HBOR_RS13415
uniprot id: E4NL73
names: Similarity
messages: Belongs to the peptidase M24B family.

469382:HBOR RS00865
gene id: 469382:HBOR_RS00865
uniprot id: L9UPD5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS04825
gene id: 469382:HBOR_RS04825
uniprot id: E4NPW2
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

469382:HBOR RS06645
gene id: 469382:HBOR_RS06645
uniprot id: E4NSG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

469382:HBOR RS17340
gene id: 469382:HBOR_RS17340
uniprot id: E4NVQ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS13815
gene id: 469382:HBOR_RS13815
uniprot id: E4NLV0
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

469382:HBOR RS12215
gene id: 469382:HBOR_RS12215
uniprot id: E4NSJ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

469382:HBOR RS14520
gene id: 469382:HBOR_RS14520
uniprot id: E4NU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS13670
gene id: 469382:HBOR_RS13670
uniprot id: E4NLS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

469382:HBOR RS10880
gene id: 469382:HBOR_RS10880
uniprot id: E4NQE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS06070
gene id: 469382:HBOR_RS06070
uniprot id: E4NRQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

469382:HBOR RS11090
gene id: 469382:HBOR_RS11090
uniprot id: E4NQI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

469382:HBOR RS00210
gene id: 469382:HBOR_RS00210
uniprot id: E4NRI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

469382:HBOR RS01630
gene id: 469382:HBOR_RS01630
uniprot id: E4NKP5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

469382:HBOR RS12530
gene id: 469382:HBOR_RS12530
uniprot id: E4NSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

469382:HBOR RS06780
gene id: 469382:HBOR_RS06780
uniprot id: E4NSZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

469382:HBOR RS04365
gene id: 469382:HBOR_RS04365
uniprot id: E4NPE6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

469382:HBOR RS00475
gene id: 469382:HBOR_RS00475
uniprot id: E4NRN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

469382:HBOR RS11700
gene id: 469382:HBOR_RS11700
uniprot id: E4NRD9
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

469382:HBOR RS10905
gene id: 469382:HBOR_RS10905
uniprot id: E4NQE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS05780
gene id: 469382:HBOR_RS05780
uniprot id: L9UZB3
names: Caution
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS04850
gene id: 469382:HBOR_RS04850
uniprot id: E4NPW7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

469382:HBOR RS13055
gene id: 469382:HBOR_RS13055
uniprot id: L9UIY8
names: Caution
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS07570
gene id: 469382:HBOR_RS07570
uniprot id: E4NKY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS04545
gene id: 469382:HBOR_RS04545
uniprot id: E4NPQ4
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

469382:HBOR RS17850
gene id: 469382:HBOR_RS17850
uniprot id: E4NW10
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS10740
gene id: 469382:HBOR_RS10740
uniprot id: E4NQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

469382:HBOR RS04565
gene id: 469382:HBOR_RS04565
uniprot id: E4NPQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

469382:HBOR RS03555
gene id: 469382:HBOR_RS03555
uniprot id: E4NNI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

469382:HBOR RS04445
gene id: 469382:HBOR_RS04445
uniprot id: E4NPG3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

469382:HBOR RS01260
gene id: 469382:HBOR_RS01260
uniprot id: E4NTC7
names: Similarity
messages: Belongs to the IMPACT family.

469382:HBOR RS05540
gene id: 469382:HBOR_RS05540
uniprot id: E4NQP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS08695
gene id: 469382:HBOR_RS08695
uniprot id: E4NMW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

469382:HBOR RS08800
gene id: 469382:HBOR_RS08800
uniprot id: E4NMY2
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS07415
gene id: 469382:HBOR_RS07415
uniprot id: E4NTQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

469382:HBOR RS13520
gene id: 469382:HBOR_RS13520
uniprot id: E4NL94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS16290
gene id: 469382:HBOR_RS16290
uniprot id: L9UVU0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS07025
gene id: 469382:HBOR_RS07025
uniprot id: E4NT42
names: Similarity
messages: Belongs to the arginase family.

469382:HBOR RS07985
gene id: 469382:HBOR_RS07985
uniprot id: E4NLL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

469382:HBOR RS08755
gene id: 469382:HBOR_RS08755
uniprot id: E4NMX2
names: Similarity
messages: Belongs to the BtpA family.

469382:HBOR RS07260
gene id: 469382:HBOR_RS07260
uniprot id: E4NTM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS10360
gene id: 469382:HBOR_RS10360
uniprot id: E4NPP1
names: Similarity
messages: Belongs to the complex I subunit 3 family.

469382:HBOR RS03150
gene id: 469382:HBOR_RS03150
uniprot id: E4NN22
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469382:HBOR RS05900
gene id: 469382:HBOR_RS05900
uniprot id: E4NR76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

469382:HBOR RS14095
gene id: 469382:HBOR_RS14095
uniprot id: E4NMF7
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

469382:HBOR RS08465
gene id: 469382:HBOR_RS08465
uniprot id: E4NMB8
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

469382:HBOR RS18195
gene id: 469382:HBOR_RS18195
uniprot id: E4NW81
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

469382:HBOR RS07495
gene id: 469382:HBOR_RS07495
uniprot id: E4NKX0
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

469382:HBOR RS01500
gene id: 469382:HBOR_RS01500
uniprot id: E4NTH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

469382:HBOR RS02090
gene id: 469382:HBOR_RS02090
uniprot id: E4NLE0
names: Subcellular Location Annotation
messages: Cytoplasm

469382:HBOR RS02850
gene id: 469382:HBOR_RS02850
uniprot id: E4NMN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS15150
gene id: 469382:HBOR_RS15150
uniprot id: L9UKZ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS07030
gene id: 469382:HBOR_RS07030
uniprot id: E4NT43
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS18385
gene id: 469382:HBOR_RS18385
uniprot id: E4NWC0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

469382:HBOR RS12150
gene id: 469382:HBOR_RS12150
uniprot id: E4NS24
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

469382:HBOR RS05060
gene id: 469382:HBOR_RS05060
uniprot id: E4NQ79
names: Similarity
messages: Belongs to the FabD family.

469382:HBOR RS09230
gene id: 469382:HBOR_RS09230
uniprot id: E4NNE5
names: Similarity
messages: Belongs to the peptidase M24B family.

469382:HBOR RS14980
gene id: 469382:HBOR_RS14980
uniprot id: E4NUC0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

469382:HBOR RS16700
gene id: 469382:HBOR_RS16700
uniprot id: E4NV06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

469382:HBOR RS00510
gene id: 469382:HBOR_RS00510
uniprot id: E4NRP2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

469382:HBOR RS18335
gene id: 469382:HBOR_RS18335
uniprot id: E4NWA9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

469382:HBOR RS05365
gene id: 469382:HBOR_RS05365
uniprot id: E4NQL4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS11445
gene id: 469382:HBOR_RS11445
uniprot id: E4NQY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

469382:HBOR RS01700
gene id: 469382:HBOR_RS01700
uniprot id: E4NKQ9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

469382:HBOR RS05085
gene id: 469382:HBOR_RS05085
uniprot id: L9V315
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS06945
gene id: 469382:HBOR_RS06945
uniprot id: E4NT27
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

469382:HBOR RS12790
gene id: 469382:HBOR_RS12790
uniprot id: E4NTA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS08925
gene id: 469382:HBOR_RS08925
uniprot id: E4NN83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

469382:HBOR RS04115
gene id: 469382:HBOR_RS04115
uniprot id: E4NP18
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

469382:HBOR RS03810
gene id: 469382:HBOR_RS03810
uniprot id: L9V251
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS15665
gene id: 469382:HBOR_RS15665
uniprot id: E4NUR3
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

469382:HBOR RS01190
gene id: 469382:HBOR_RS01190
uniprot id: E4NSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

469382:HBOR RS14270
gene id: 469382:HBOR_RS14270
uniprot id: E4NMJ5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

469382:HBOR RS00505
gene id: 469382:HBOR_RS00505
uniprot id: E4NRP1
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

469382:HBOR RS16705
gene id: 469382:HBOR_RS16705
uniprot id: E4NV07
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS02570
gene id: 469382:HBOR_RS02570
uniprot id: E4NM35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the oxidation of methyl-H(4)MPT to methylene-H(4)MPT.
messages: Cytoplasm

469382:HBOR RS08045
gene id: 469382:HBOR_RS08045
uniprot id: E4NLN1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

469382:HBOR RS00050
gene id: 469382:HBOR_RS00050
uniprot id: E4NQZ7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

469382:HBOR RS09475
gene id: 469382:HBOR_RS09475
uniprot id: L9UGD5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS13270
gene id: 469382:HBOR_RS13270
uniprot id: E4NTY6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

469382:HBOR RS06125
gene id: 469382:HBOR_RS06125
uniprot id: E4NRR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

469382:HBOR RS01185
gene id: 469382:HBOR_RS01185
uniprot id: E4NSX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

469382:HBOR RS10460
gene id: 469382:HBOR_RS10460
uniprot id: E4NPY6
names: Similarity
messages: Belongs to the peptidase S9C family.

469382:HBOR RS15050
gene id: 469382:HBOR_RS15050
uniprot id: E4NUD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

469382:HBOR RS18400
gene id: 469382:HBOR_RS18400
uniprot id: E4NWC3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS03755
gene id: 469382:HBOR_RS03755
uniprot id: E4NNM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

469382:HBOR RS00515
gene id: 469382:HBOR_RS00515
uniprot id: E4NS34
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

469382:HBOR RS01360
gene id: 469382:HBOR_RS01360
uniprot id: E4NTE6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

469382:HBOR RS17315
gene id: 469382:HBOR_RS17315
uniprot id: E4NVQ1
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS14065
gene id: 469382:HBOR_RS14065
uniprot id: L9UT55
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS01695
gene id: 469382:HBOR_RS01695
uniprot id: E4NKQ8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

469382:HBOR RS06855
gene id: 469382:HBOR_RS06855
uniprot id: E4NT08
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS03500
gene id: 469382:HBOR_RS03500
uniprot id: E4NNH0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

469382:HBOR RS09480
gene id: 469382:HBOR_RS09480
uniprot id: L9UGL0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS04965
gene id: 469382:HBOR_RS04965
uniprot id: E4NQ60
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

469382:HBOR RS13050
gene id: 469382:HBOR_RS13050
uniprot id: E4NTU3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469382:HBOR RS17430
gene id: 469382:HBOR_RS17430
uniprot id: E4NVS5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469382:HBOR RS07890
gene id: 469382:HBOR_RS07890
uniprot id: E4NLK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS04040
gene id: 469382:HBOR_RS04040
uniprot id: E4NP03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

469382:HBOR RS15700
gene id: 469382:HBOR_RS15700
uniprot id: E4NUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

469382:HBOR RS16370
gene id: 469382:HBOR_RS16370
uniprot id: E4NVP2
names: Similarity
messages: Belongs to the peptidase S8 family.

469382:HBOR RS18470
gene id: 469382:HBOR_RS18470
uniprot id: E4NWE0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

469382:HBOR RS12845
gene id: 469382:HBOR_RS12845
uniprot id: E4NTB5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

469382:HBOR RS06640
gene id: 469382:HBOR_RS06640
uniprot id: E4NSG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

469382:HBOR RS05850
gene id: 469382:HBOR_RS05850
uniprot id: E4NR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

469382:HBOR RS10805
gene id: 469382:HBOR_RS10805
uniprot id: E4NQC7
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS06935
gene id: 469382:HBOR_RS06935
uniprot id: E4NT25
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

469382:HBOR RS01580
gene id: 469382:HBOR_RS01580
uniprot id: E4NTI6
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

469382:HBOR RS10385
gene id: 469382:HBOR_RS10385
uniprot id: E4NPP6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

469382:HBOR RS04955
gene id: 469382:HBOR_RS04955
uniprot id: E4NQ58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

469382:HBOR RS17945
gene id: 469382:HBOR_RS17945
uniprot id: E4NW30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

469382:HBOR RS12275
gene id: 469382:HBOR_RS12275
uniprot id: E4NSK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

469382:HBOR RS02700
gene id: 469382:HBOR_RS02700
uniprot id: E4NM61
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

469382:HBOR RS09430
gene id: 469382:HBOR_RS09430
uniprot id: E4NNQ9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

469382:HBOR RS11025
gene id: 469382:HBOR_RS11025
uniprot id: E4NQH2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

469382:HBOR RS14540
gene id: 469382:HBOR_RS14540
uniprot id: E4NU28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS11020
gene id: 469382:HBOR_RS11020
uniprot id: E4NQH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

469382:HBOR RS08195
gene id: 469382:HBOR_RS08195
uniprot id: E4NLR4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

469382:HBOR RS04180
gene id: 469382:HBOR_RS04180
uniprot id: E4NPA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

469382:HBOR RS14920
gene id: 469382:HBOR_RS14920
uniprot id: E4NUA8
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS06715
gene id: 469382:HBOR_RS06715
uniprot id: E4NSI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

469382:HBOR RS18735
gene id: 469382:HBOR_RS18735
uniprot id: E4NWJ5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469382:HBOR RS09595
gene id: 469382:HBOR_RS09595
uniprot id: E4NNU3
names: Similarity
messages: Belongs to the SCO1/2 family.

469382:HBOR RS12775
gene id: 469382:HBOR_RS12775
uniprot id: E4NTA1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS08825
gene id: 469382:HBOR_RS08825
uniprot id: E4NMY7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

469382:HBOR RS00195
gene id: 469382:HBOR_RS00195
uniprot id: E4NRH9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

469382:HBOR RS12885
gene id: 469382:HBOR_RS12885
uniprot id: L9UJ99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS15930
gene id: 469382:HBOR_RS15930
uniprot id: E4NVF4
names: Subcellular Location Annotation
messages: Cytoplasm

469382:HBOR RS05560
gene id: 469382:HBOR_RS05560
uniprot id: E4NQQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

469382:HBOR RS12070
gene id: 469382:HBOR_RS12070
uniprot id: E4NS09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

469382:HBOR RS11735
gene id: 469382:HBOR_RS11735
uniprot id: E4NRE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

469382:HBOR RS10365
gene id: 469382:HBOR_RS10365
uniprot id: E4NPP2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

469382:HBOR RS05205
gene id: 469382:HBOR_RS05205
uniprot id: E4NQA7
names: Similarity
messages: Belongs to the TrpF family.

469382:HBOR RS13045
gene id: 469382:HBOR_RS13045
uniprot id: E4NTU2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

469382:HBOR RS07380
gene id: 469382:HBOR_RS07380
uniprot id: E4NTP9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

469382:HBOR RS10040
gene id: 469382:HBOR_RS10040
uniprot id: E4NPH7
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS07875
gene id: 469382:HBOR_RS07875
uniprot id: E4NLJ6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

469382:HBOR RS12390
gene id: 469382:HBOR_RS12390
uniprot id: E4NSM7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

469382:HBOR RS00680
gene id: 469382:HBOR_RS00680
uniprot id: E4NS69
names: Similarity
messages: Belongs to the HMBS family.

469382:HBOR RS13645
gene id: 469382:HBOR_RS13645
uniprot id: E4NLR7
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

469382:HBOR RS03600
gene id: 469382:HBOR_RS03600
uniprot id: E4NNJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

469382:HBOR RS00490
gene id: 469382:HBOR_RS00490
uniprot id: E4NRN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

469382:HBOR RS02810
gene id: 469382:HBOR_RS02810
uniprot id: E4NMM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS02930
gene id: 469382:HBOR_RS02930
uniprot id: E4NMQ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

469382:HBOR RS13430
gene id: 469382:HBOR_RS13430
uniprot id: L9UIC6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14550
gene id: 469382:HBOR_RS14550
uniprot id: E4NU30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS06975
gene id: 469382:HBOR_RS06975
uniprot id: E4NT33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS18150
gene id: 469382:HBOR_RS18150
uniprot id: E4NW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

469382:HBOR RS17130
gene id: 469382:HBOR_RS17130
uniprot id: L9UXG7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS08215
gene id: 469382:HBOR_RS08215
uniprot id: E4NM66
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

469382:HBOR RS09835
gene id: 469382:HBOR_RS09835
uniprot id: E4NP65
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

469382:HBOR RS13805
gene id: 469382:HBOR_RS13805
uniprot id: E4NLU8
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

469382:HBOR RS04960
gene id: 469382:HBOR_RS04960
uniprot id: E4NQ59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

469382:HBOR RS12355
gene id: 469382:HBOR_RS12355
uniprot id: E4NSM0
names: Similarity
messages: Belongs to the UPF0440 family.

469382:HBOR RS05520
gene id: 469382:HBOR_RS05520
uniprot id: E4NQP5
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

469382:HBOR RS10420
gene id: 469382:HBOR_RS10420
uniprot id: E4NPX8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

469382:HBOR RS18585
gene id: 469382:HBOR_RS18585
uniprot id: E4NWG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the halobacterial S-layer protein family.
messages: Cell membrane
messages: Membrane
messages: S-layer

469382:HBOR RS00370
gene id: 469382:HBOR_RS00370
uniprot id: E4NRL5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

469382:HBOR RS10345
gene id: 469382:HBOR_RS10345
uniprot id: E4NPN8
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS00170
gene id: 469382:HBOR_RS00170
uniprot id: E4NRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

469382:HBOR RS07900
gene id: 469382:HBOR_RS07900
uniprot id: E4NLK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS10370
gene id: 469382:HBOR_RS10370
uniprot id: E4NPP3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS04435
gene id: 469382:HBOR_RS04435
uniprot id: E4NPG1
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS15450
gene id: 469382:HBOR_RS15450
uniprot id: L9ULC8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS12370
gene id: 469382:HBOR_RS12370
uniprot id: E4NSM3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

469382:HBOR RS06865
gene id: 469382:HBOR_RS06865
uniprot id: E4NT10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS05010
gene id: 469382:HBOR_RS05010
uniprot id: E4NQ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

469382:HBOR RS03495
gene id: 469382:HBOR_RS03495
uniprot id: E4NNG9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

469382:HBOR RS06665
gene id: 469382:HBOR_RS06665
uniprot id: E4NSH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

469382:HBOR RS05760
gene id: 469382:HBOR_RS05760
uniprot id: E4NR46
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

469382:HBOR RS04190
gene id: 469382:HBOR_RS04190
uniprot id: E4NPB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS10220
gene id: 469382:HBOR_RS10220
uniprot id: E4NPL2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

469382:HBOR RS05730
gene id: 469382:HBOR_RS05730
uniprot id: E4NR40
names: Cofactor
messages: Binds 1 copper ion per subunit.

469382:HBOR RS00450
gene id: 469382:HBOR_RS00450
uniprot id: E4NRN0
names: Similarity
messages: Belongs to the UPF0200 family.

469382:HBOR RS12270
gene id: 469382:HBOR_RS12270
uniprot id: E4NSK3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

469382:HBOR RS03905
gene id: 469382:HBOR_RS03905
uniprot id: E4NNX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

469382:HBOR RS12500
gene id: 469382:HBOR_RS12500
uniprot id: L9UJ98
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS04705
gene id: 469382:HBOR_RS04705
uniprot id: E4NPT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

469382:HBOR RS13040
gene id: 469382:HBOR_RS13040
uniprot id: L9UIB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS06845
gene id: 469382:HBOR_RS06845
uniprot id: E4NT05
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469382:HBOR RS16175
gene id: 469382:HBOR_RS16175
uniprot id: E4NVK3
names: Function
messages: Part of a potassium transport system.

469382:HBOR RS06250
gene id: 469382:HBOR_RS06250
uniprot id: E4NRU1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

469382:HBOR RS00090
gene id: 469382:HBOR_RS00090
uniprot id: L9USY2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS09100
gene id: 469382:HBOR_RS09100
uniprot id: E4NNB8
names: Similarity
messages: Belongs to the FUN14 family.

469382:HBOR RS05465
gene id: 469382:HBOR_RS05465
uniprot id: E4NQN4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

469382:HBOR RS02475
gene id: 469382:HBOR_RS02475
uniprot id: E4NM16
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

469382:HBOR RS11770
gene id: 469382:HBOR_RS11770
uniprot id: L9UGL4
names: Caution
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS16920
gene id: 469382:HBOR_RS16920
uniprot id: L9UZA7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS15750
gene id: 469382:HBOR_RS15750
uniprot id: E4NUT1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

469382:HBOR RS08350
gene id: 469382:HBOR_RS08350
uniprot id: E4NM94
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

469382:HBOR RS13315
gene id: 469382:HBOR_RS13315
uniprot id: E4NL52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

469382:HBOR RS00035
gene id: 469382:HBOR_RS00035
uniprot id: E4NQZ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS07155
gene id: 469382:HBOR_RS07155
uniprot id: E4NTK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS15950
gene id: 469382:HBOR_RS15950
uniprot id: E4NVF8
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

469382:HBOR RS02445
gene id: 469382:HBOR_RS02445
uniprot id: L9URQ8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS13060
gene id: 469382:HBOR_RS13060
uniprot id: E4NTU5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

469382:HBOR RS18850
gene id: 469382:HBOR_RS18850
uniprot id: E4NWM0
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS07425
gene id: 469382:HBOR_RS07425
uniprot id: E4NTQ8
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

469382:HBOR RS05240
gene id: 469382:HBOR_RS05240
uniprot id: E4NQB3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS05170
gene id: 469382:HBOR_RS05170
uniprot id: L9UZU3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS13450
gene id: 469382:HBOR_RS13450
uniprot id: E4NL80
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

469382:HBOR RS17035
gene id: 469382:HBOR_RS17035
uniprot id: L9UXI6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS16200
gene id: 469382:HBOR_RS16200
uniprot id: E4NVK9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

469382:HBOR RS09965
gene id: 469382:HBOR_RS09965
uniprot id: E4NP92
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

469382:HBOR RS14315
gene id: 469382:HBOR_RS14315
uniprot id: E4NMK4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

469382:HBOR RS18405
gene id: 469382:HBOR_RS18405
uniprot id: E4NWC4
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS03005
gene id: 469382:HBOR_RS03005
uniprot id: E4NMR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

469382:HBOR RS05040
gene id: 469382:HBOR_RS05040
uniprot id: E4NQ75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

469382:HBOR RS12025
gene id: 469382:HBOR_RS12025
uniprot id: E4NS00
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

469382:HBOR RS01650
gene id: 469382:HBOR_RS01650
uniprot id: E4NKP9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

469382:HBOR RS00245
gene id: 469382:HBOR_RS00245
uniprot id: E4NRJ0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

469382:HBOR RS18760
gene id: 469382:HBOR_RS18760
uniprot id: L9UMK5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS07085
gene id: 469382:HBOR_RS07085
uniprot id: E4NT50
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS11330
gene id: 469382:HBOR_RS11330
uniprot id: E4NQV9
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

469382:HBOR RS00325
gene id: 469382:HBOR_RS00325
uniprot id: E4NRK6
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

469382:HBOR RS15400
gene id: 469382:HBOR_RS15400
uniprot id: E4NUL2
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

469382:HBOR RS03220
gene id: 469382:HBOR_RS03220
uniprot id: L9UST6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS15350
gene id: 469382:HBOR_RS15350
uniprot id: E4NUK2
names: Similarity
messages: Belongs to the cytochrome P450 family.

469382:HBOR RS15780
gene id: 469382:HBOR_RS15780
uniprot id: L9ULT5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A 'suicide' enzyme that participates in biotin synthesis. Catalyzes the formation of (S)-8-amino-7-oxononanoate (DAN-carbamic acid) from (7R,8S)-8-amino-7-(carboxyamino)nonanoate (DAN), a function equivalent to the cannonical BioA reaction and the first half-reaction of BioD. The cellular requirement for biotin is thought be low enough that this single turnover enzyme supplies a sufficient amount of the cofactor. Overall it catalyzes three reactions: formation of a covalent linkage with 8-amino-7-oxononanoate to yield a BioU-DAN conjugate at the epsilon-amino group of Lys124 of BioU using NAD(P)H, carboxylation of the conjugate to form BioU-DAN-carbamic acid, and release of DAN-carbamic acid using NAD(P)+.
messages: Belongs to the BioU family.
messages: In cannonical biotin synthesis a pimeloyl-conjugate is transformed into biotin by the subsequent action of BioF, BioA, BioD and BioB. This enzyme replaces BioA and performs the first half-reaction of BioD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS06990
gene id: 469382:HBOR_RS06990
uniprot id: E4NT36
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

469382:HBOR RS10185
gene id: 469382:HBOR_RS10185
uniprot id: E4NPK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

469382:HBOR RS06860
gene id: 469382:HBOR_RS06860
uniprot id: E4NT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS16625
gene id: 469382:HBOR_RS16625
uniprot id: E4NUZ1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

469382:HBOR RS02840
gene id: 469382:HBOR_RS02840
uniprot id: E4NMN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS10965
gene id: 469382:HBOR_RS10965
uniprot id: E4NQF9
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

469382:HBOR RS04160
gene id: 469382:HBOR_RS04160
uniprot id: L9V491
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14735
gene id: 469382:HBOR_RS14735
uniprot id: L9ULK6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS17140
gene id: 469382:HBOR_RS17140
uniprot id: E4NV94
names: Similarity
messages: Belongs to the PrpD family.

469382:HBOR RS05910
gene id: 469382:HBOR_RS05910
uniprot id: E4NR78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

469382:HBOR RS17360
gene id: 469382:HBOR_RS17360
uniprot id: E4NVR0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469382:HBOR RS01610
gene id: 469382:HBOR_RS01610
uniprot id: E4NTJ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS13175
gene id: 469382:HBOR_RS13175
uniprot id: E4NTW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

469382:HBOR RS10135
gene id: 469382:HBOR_RS10135
uniprot id: L9UFL2
names: Caution
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS13665
gene id: 469382:HBOR_RS13665
uniprot id: E4NLR9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

469382:HBOR RS04255
gene id: 469382:HBOR_RS04255
uniprot id: E4NPC4
names: Similarity
messages: Belongs to the asparaginase 1 family.

469382:HBOR RS13280
gene id: 469382:HBOR_RS13280
uniprot id: E4NL44
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS05030
gene id: 469382:HBOR_RS05030
uniprot id: E4NQ73
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

469382:HBOR RS02965
gene id: 469382:HBOR_RS02965
uniprot id: L9USY0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS00420
gene id: 469382:HBOR_RS00420
uniprot id: E4NRM5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

469382:HBOR RS10655
gene id: 469382:HBOR_RS10655
uniprot id: L9UFQ7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS09425
gene id: 469382:HBOR_RS09425
uniprot id: E4NNQ8
names: Similarity
messages: Belongs to the selenium-binding protein family.

469382:HBOR RS16750
gene id: 469382:HBOR_RS16750
uniprot id: E4NV16
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

469382:HBOR RS04325
gene id: 469382:HBOR_RS04325
uniprot id: E4NPD8
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS02545
gene id: 469382:HBOR_RS02545
uniprot id: E4NM30
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

469382:HBOR RS18590
gene id: 469382:HBOR_RS18590
uniprot id: L9UMH4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS10970
gene id: 469382:HBOR_RS10970
uniprot id: E4NQG0
names: Caution
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS09485
gene id: 469382:HBOR_RS09485
uniprot id: E4NNS1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS05790
gene id: 469382:HBOR_RS05790
uniprot id: E4NR53
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

469382:HBOR RS05185
gene id: 469382:HBOR_RS05185
uniprot id: E4NQA3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

469382:HBOR RS17055
gene id: 469382:HBOR_RS17055
uniprot id: E4NV78
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

469382:HBOR RS07105
gene id: 469382:HBOR_RS07105
uniprot id: E4NTJ5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

469382:HBOR RS16915
gene id: 469382:HBOR_RS16915
uniprot id: E4NV50
names: Similarity
messages: Belongs to the TPP enzyme family.

469382:HBOR RS06155
gene id: 469382:HBOR_RS06155
uniprot id: E4NRS3
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS13180
gene id: 469382:HBOR_RS13180
uniprot id: E4NTW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Homodimer.

469382:HBOR RS15475
gene id: 469382:HBOR_RS15475
uniprot id: E4NUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS10825
gene id: 469382:HBOR_RS10825
uniprot id: E4NQD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

469382:HBOR RS11350
gene id: 469382:HBOR_RS11350
uniprot id: E4NQW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

469382:HBOR RS01805
gene id: 469382:HBOR_RS01805
uniprot id: L9UFZ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS12675
gene id: 469382:HBOR_RS12675
uniprot id: E4NT80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

469382:HBOR RS00845
gene id: 469382:HBOR_RS00845
uniprot id: E4NSA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

469382:HBOR RS12230
gene id: 469382:HBOR_RS12230
uniprot id: E4NSJ5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

469382:HBOR RS13605
gene id: 469382:HBOR_RS13605
uniprot id: E4NLB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

469382:HBOR RS06880
gene id: 469382:HBOR_RS06880
uniprot id: E4NT14
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

469382:HBOR RS00835
gene id: 469382:HBOR_RS00835
uniprot id: E4NSA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS16840
gene id: 469382:HBOR_RS16840
uniprot id: E4NV35
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

469382:HBOR RS09245
gene id: 469382:HBOR_RS09245
uniprot id: E4NNE8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

469382:HBOR RS17145
gene id: 469382:HBOR_RS17145
uniprot id: L9UX25
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS08450
gene id: 469382:HBOR_RS08450
uniprot id: E4NMB5
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS01285
gene id: 469382:HBOR_RS01285
uniprot id: E4NTD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

469382:HBOR RS11105
gene id: 469382:HBOR_RS11105
uniprot id: E4NQI8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS00005
gene id: 469382:HBOR_RS00005
uniprot id: E4NQY8
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

469382:HBOR RS16140
gene id: 469382:HBOR_RS16140
uniprot id: E4NVJ6
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

469382:HBOR RS14820
gene id: 469382:HBOR_RS14820
uniprot id: E4NU87
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS04225
gene id: 469382:HBOR_RS04225
uniprot id: E4NPB8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

469382:HBOR RS17800
gene id: 469382:HBOR_RS17800
uniprot id: E4NVZ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS02970
gene id: 469382:HBOR_RS02970
uniprot id: E4NMQ8
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

469382:HBOR RS03405
gene id: 469382:HBOR_RS03405
uniprot id: E4NN75
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

469382:HBOR RS18010
gene id: 469382:HBOR_RS18010
uniprot id: E4NW43
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

469382:HBOR RS13720
gene id: 469382:HBOR_RS13720
uniprot id: E4NLT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

469382:HBOR RS11395
gene id: 469382:HBOR_RS11395
uniprot id: E4NQX1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

469382:HBOR RS05825
gene id: 469382:HBOR_RS05825
uniprot id: E4NR61
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

469382:HBOR RS11550
gene id: 469382:HBOR_RS11550
uniprot id: E4NRA9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

469382:HBOR RS02345
gene id: 469382:HBOR_RS02345
uniprot id: E4NLZ0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469382:HBOR RS08545
gene id: 469382:HBOR_RS08545
uniprot id: E4NMD4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

469382:HBOR RS14120
gene id: 469382:HBOR_RS14120
uniprot id: L9USJ7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS11570
gene id: 469382:HBOR_RS11570
uniprot id: E4NRB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

469382:HBOR RS05070
gene id: 469382:HBOR_RS05070
uniprot id: E4NQ81
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

469382:HBOR RS13925
gene id: 469382:HBOR_RS13925
uniprot id: L9V2V0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS10815
gene id: 469382:HBOR_RS10815
uniprot id: E4NQC9
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS14210
gene id: 469382:HBOR_RS14210
uniprot id: E4NMI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

469382:HBOR RS06380
gene id: 469382:HBOR_RS06380
uniprot id: E4NSB4
names: Similarity
messages: Belongs to the TBP family.

469382:HBOR RS06140
gene id: 469382:HBOR_RS06140
uniprot id: E4NRS0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS02480
gene id: 469382:HBOR_RS02480
uniprot id: E4NM17
names: Function
messages: Part of a potassium transport system.

469382:HBOR RS14435
gene id: 469382:HBOR_RS14435
uniprot id: E4NU05
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS11990
gene id: 469382:HBOR_RS11990
uniprot id: E4NRZ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

469382:HBOR RS11050
gene id: 469382:HBOR_RS11050
uniprot id: E4NQH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

469382:HBOR RS17905
gene id: 469382:HBOR_RS17905
uniprot id: E4NW21
names: Similarity
messages: Belongs to the UPF0045 family.

469382:HBOR RS16065
gene id: 469382:HBOR_RS16065
uniprot id: E4NVI1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS01165
gene id: 469382:HBOR_RS01165
uniprot id: E4NSW6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

469382:HBOR RS01880
gene id: 469382:HBOR_RS01880
uniprot id: E4NKU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS15155
gene id: 469382:HBOR_RS15155
uniprot id: E4NUF8
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS03045
gene id: 469382:HBOR_RS03045
uniprot id: E4NMS6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

469382:HBOR RS00480
gene id: 469382:HBOR_RS00480
uniprot id: E4NRN6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

469382:HBOR RS03875
gene id: 469382:HBOR_RS03875
uniprot id: L9V1P9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS08135
gene id: 469382:HBOR_RS08135
uniprot id: E4NLP9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

469382:HBOR RS10310
gene id: 469382:HBOR_RS10310
uniprot id: E4NPN1
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS10350
gene id: 469382:HBOR_RS10350
uniprot id: E4NPN9
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

469382:HBOR RS05855
gene id: 469382:HBOR_RS05855
uniprot id: E4NR67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

469382:HBOR RS03925
gene id: 469382:HBOR_RS03925
uniprot id: E4NNX9
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

469382:HBOR RS02060
gene id: 469382:HBOR_RS02060
uniprot id: E4NLD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

469382:HBOR RS04985
gene id: 469382:HBOR_RS04985
uniprot id: E4NQ64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

469382:HBOR RS00550
gene id: 469382:HBOR_RS00550
uniprot id: L9UQ79
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS00060
gene id: 469382:HBOR_RS00060
uniprot id: E4NQZ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS07165
gene id: 469382:HBOR_RS07165
uniprot id: E4NTK7
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS00525
gene id: 469382:HBOR_RS00525
uniprot id: E4NS36
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

469382:HBOR RS11425
gene id: 469382:HBOR_RS11425
uniprot id: E4NQX7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

469382:HBOR RS01150
gene id: 469382:HBOR_RS01150
uniprot id: E4NSW3
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS12830
gene id: 469382:HBOR_RS12830
uniprot id: E4NTB2
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

469382:HBOR RS07515
gene id: 469382:HBOR_RS07515
uniprot id: E4NKX4
names: Similarity
messages: Belongs to the GARS family.

469382:HBOR RS07310
gene id: 469382:HBOR_RS07310
uniprot id: E4NTN6
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS17475
gene id: 469382:HBOR_RS17475
uniprot id: E4NVT4
names: Similarity
messages: Belongs to the group II decarboxylase family.

469382:HBOR RS07015
gene id: 469382:HBOR_RS07015
uniprot id: E4NT40
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

469382:HBOR RS03090
gene id: 469382:HBOR_RS03090
uniprot id: E4NN10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

469382:HBOR RS02380
gene id: 469382:HBOR_RS02380
uniprot id: E4NLZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Membrane

469382:HBOR RS08550
gene id: 469382:HBOR_RS08550
uniprot id: E4NMD5
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS09300
gene id: 469382:HBOR_RS09300
uniprot id: E4NNN3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

469382:HBOR RS02170
gene id: 469382:HBOR_RS02170
uniprot id: E4NLF8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

469382:HBOR RS13810
gene id: 469382:HBOR_RS13810
uniprot id: E4NLU9
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

469382:HBOR RS17830
gene id: 469382:HBOR_RS17830
uniprot id: L9V3G1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS12760
gene id: 469382:HBOR_RS12760
uniprot id: E4NT98
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

469382:HBOR RS10375
gene id: 469382:HBOR_RS10375
uniprot id: E4NPP4
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS12680
gene id: 469382:HBOR_RS12680
uniprot id: E4NT81
names: Cofactor
messages: The crystal structure with reduced Cu(1+) has also been determined.

469382:HBOR RS10630
gene id: 469382:HBOR_RS10630
uniprot id: E4NQ20
names: Similarity
messages: Belongs to the Dps family.

469382:HBOR RS17095
gene id: 469382:HBOR_RS17095
uniprot id: E4NV86
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS05020
gene id: 469382:HBOR_RS05020
uniprot id: E4NQ71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

469382:HBOR RS17955
gene id: 469382:HBOR_RS17955
uniprot id: E4NW32
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

469382:HBOR RS11530
gene id: 469382:HBOR_RS11530
uniprot id: E4NRA5
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

469382:HBOR RS12250
gene id: 469382:HBOR_RS12250
uniprot id: E4NSJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

469382:HBOR RS14895
gene id: 469382:HBOR_RS14895
uniprot id: L9UKX8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS02430
gene id: 469382:HBOR_RS02430
uniprot id: E4NM06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

469382:HBOR RS08025
gene id: 469382:HBOR_RS08025
uniprot id: E4NLM7
names: Subcellular Location Annotation
messages: Cell membrane

469382:HBOR RS16870
gene id: 469382:HBOR_RS16870
uniprot id: E4NV41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

469382:HBOR RS13685
gene id: 469382:HBOR_RS13685
uniprot id: E4NLS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

469382:HBOR RS10755
gene id: 469382:HBOR_RS10755
uniprot id: E4NQB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

469382:HBOR RS01155
gene id: 469382:HBOR_RS01155
uniprot id: L9UPP5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS00920
gene id: 469382:HBOR_RS00920
uniprot id: E4NSR6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

469382:HBOR RS08980
gene id: 469382:HBOR_RS08980
uniprot id: E4NN94
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469382:HBOR RS02340
gene id: 469382:HBOR_RS02340
uniprot id: E4NLY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

469382:HBOR RS13575
gene id: 469382:HBOR_RS13575
uniprot id: E4NLA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

469382:HBOR RS14225
gene id: 469382:HBOR_RS14225
uniprot id: E4NMI5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

469382:HBOR RS14915
gene id: 469382:HBOR_RS14915
uniprot id: E4NUA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

469382:HBOR RS13760
gene id: 469382:HBOR_RS13760
uniprot id: E4NLT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

469382:HBOR RS02985
gene id: 469382:HBOR_RS02985
uniprot id: E4NMR2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

469382:HBOR RS03135
gene id: 469382:HBOR_RS03135
uniprot id: E4NN19
names: Function
messages: Part of a potassium transport system.

469382:HBOR RS00230
gene id: 469382:HBOR_RS00230
uniprot id: E4NRI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

469382:HBOR RS05410
gene id: 469382:HBOR_RS05410
uniprot id: L9UZ42
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS08010
gene id: 469382:HBOR_RS08010
uniprot id: E4NLM4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

469382:HBOR RS03085
gene id: 469382:HBOR_RS03085
uniprot id: E4NN09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

469382:HBOR RS03950
gene id: 469382:HBOR_RS03950
uniprot id: E4NNY4
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS07585
gene id: 469382:HBOR_RS07585
uniprot id: E4NKY8
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

469382:HBOR RS13355
gene id: 469382:HBOR_RS13355
uniprot id: E4NL60
names: Similarity
messages: Belongs to the UPF0146 family.

469382:HBOR RS06730
gene id: 469382:HBOR_RS06730
uniprot id: E4NSY3
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

469382:HBOR RS04845
gene id: 469382:HBOR_RS04845
uniprot id: E4NPW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

469382:HBOR RS08640
gene id: 469382:HBOR_RS08640
uniprot id: E4NMU9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS07465
gene id: 469382:HBOR_RS07465
uniprot id: L9UXK1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS00410
gene id: 469382:HBOR_RS00410
uniprot id: L9UQ99
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS03880
gene id: 469382:HBOR_RS03880
uniprot id: E4NNX0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

469382:HBOR RS06045
gene id: 469382:HBOR_RS06045
uniprot id: E4NRQ4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

469382:HBOR RS09275
gene id: 469382:HBOR_RS09275
uniprot id: E4NNF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

469382:HBOR RS07190
gene id: 469382:HBOR_RS07190
uniprot id: E4NTL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

469382:HBOR RS16645
gene id: 469382:HBOR_RS16645
uniprot id: E4NUZ5
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

469382:HBOR RS09115
gene id: 469382:HBOR_RS09115
uniprot id: E4NNC1
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

469382:HBOR RS10670
gene id: 469382:HBOR_RS10670
uniprot id: E4NQ28
names: Subcellular Location Annotation
messages: Cytoplasm

469382:HBOR RS02405
gene id: 469382:HBOR_RS02405
uniprot id: L9URA7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS10530
gene id: 469382:HBOR_RS10530
uniprot id: E4NQ00
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

469382:HBOR RS13770
gene id: 469382:HBOR_RS13770
uniprot id: E4NLU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

469382:HBOR RS05045
gene id: 469382:HBOR_RS05045
uniprot id: E4NQ76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

469382:HBOR RS06420
gene id: 469382:HBOR_RS06420
uniprot id: L9V005
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS13015
gene id: 469382:HBOR_RS13015
uniprot id: E4NTT7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

469382:HBOR RS11255
gene id: 469382:HBOR_RS11255
uniprot id: E4NQU4
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS06775
gene id: 469382:HBOR_RS06775
uniprot id: E4NSZ2
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS01270
gene id: 469382:HBOR_RS01270
uniprot id: E4NTC9
names: Similarity
messages: Belongs to the peptidase S9C family.

469382:HBOR RS04390
gene id: 469382:HBOR_RS04390
uniprot id: E4NPF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

469382:HBOR RS17535
gene id: 469382:HBOR_RS17535
uniprot id: E4NVU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

469382:HBOR RS00960
gene id: 469382:HBOR_RS00960
uniprot id: E4NSS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS18230
gene id: 469382:HBOR_RS18230
uniprot id: E4NW88
names: Similarity
messages: Belongs to the UPF0145 family.

469382:HBOR RS11760
gene id: 469382:HBOR_RS11760
uniprot id: E4NRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

469382:HBOR RS18325
gene id: 469382:HBOR_RS18325
uniprot id: E4NWA7
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS02670
gene id: 469382:HBOR_RS02670
uniprot id: E4NM55
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

469382:HBOR RS01025
gene id: 469382:HBOR_RS01025
uniprot id: E4NST8
names: Similarity
messages: Belongs to the aspartokinase family.

469382:HBOR RS04085
gene id: 469382:HBOR_RS04085
uniprot id: E4NP12
names: Similarity
messages: Belongs to the peptidase S8 family.

469382:HBOR RS10245
gene id: 469382:HBOR_RS10245
uniprot id: E4NPL7
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS06460
gene id: 469382:HBOR_RS06460
uniprot id: L9V085
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS16890
gene id: 469382:HBOR_RS16890
uniprot id: E4NV45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS04290
gene id: 469382:HBOR_RS04290
uniprot id: E4NPD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the halobacterial S-layer protein family.
messages: Cell membrane
messages: Membrane
messages: S-layer

469382:HBOR RS01410
gene id: 469382:HBOR_RS01410
uniprot id: E4NTF6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

469382:HBOR RS11010
gene id: 469382:HBOR_RS11010
uniprot id: E4NQG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

469382:HBOR RS01830
gene id: 469382:HBOR_RS01830
uniprot id: E4NKT7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

469382:HBOR RS11430
gene id: 469382:HBOR_RS11430
uniprot id: E4NQX8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

469382:HBOR RS01425
gene id: 469382:HBOR_RS01425
uniprot id: E4NTF9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

469382:HBOR RS05810
gene id: 469382:HBOR_RS05810
uniprot id: E4NR58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

469382:HBOR RS02865
gene id: 469382:HBOR_RS02865
uniprot id: E4NMN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

469382:HBOR RS18815
gene id: 469382:HBOR_RS18815
uniprot id: E4NWL3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

469382:HBOR RS00455
gene id: 469382:HBOR_RS00455
uniprot id: E4NRN1
names: Similarity
messages: Belongs to the UPF0201 family.

469382:HBOR RS15530
gene id: 469382:HBOR_RS15530
uniprot id: E4NUN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

469382:HBOR RS00650
gene id: 469382:HBOR_RS00650
uniprot id: E4NS63
names: Similarity
messages: Belongs to the P(II) protein family.

469382:HBOR RS13260
gene id: 469382:HBOR_RS13260
uniprot id: E4NTY4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

469382:HBOR RS05755
gene id: 469382:HBOR_RS05755
uniprot id: E4NR45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

469382:HBOR RS10380
gene id: 469382:HBOR_RS10380
uniprot id: E4NPP5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

469382:HBOR RS02185
gene id: 469382:HBOR_RS02185
uniprot id: E4NLG1
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS10680
gene id: 469382:HBOR_RS10680
uniprot id: E4NQ30
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS02855
gene id: 469382:HBOR_RS02855
uniprot id: E4NMN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS05035
gene id: 469382:HBOR_RS05035
uniprot id: E4NQ74
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

469382:HBOR RS10320
gene id: 469382:HBOR_RS10320
uniprot id: E4NPN3
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS12505
gene id: 469382:HBOR_RS12505
uniprot id: E4NSQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

469382:HBOR RS08660
gene id: 469382:HBOR_RS08660
uniprot id: E4NMV4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS08845
gene id: 469382:HBOR_RS08845
uniprot id: E4NMZ1
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS16105
gene id: 469382:HBOR_RS16105
uniprot id: E4NVI9
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

469382:HBOR RS11985
gene id: 469382:HBOR_RS11985
uniprot id: E4NRZ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS06745
gene id: 469382:HBOR_RS06745
uniprot id: E4NSY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

469382:HBOR RS00415
gene id: 469382:HBOR_RS00415
uniprot id: E4NRM4
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

469382:HBOR RS12090
gene id: 469382:HBOR_RS12090
uniprot id: L9UI48
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS00340
gene id: 469382:HBOR_RS00340
uniprot id: E4NRK9
names: Subcellular Location Annotation
messages: Nucleus

469382:HBOR RS08415
gene id: 469382:HBOR_RS08415
uniprot id: E4NMA8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469382:HBOR RS03015
gene id: 469382:HBOR_RS03015
uniprot id: E4NMR9
names: Similarity
messages: Belongs to the AOR/FOR family.

469382:HBOR RS20435
gene id: 469382:HBOR_RS20435
uniprot id: E4NR07
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

469382:HBOR RS01245
gene id: 469382:HBOR_RS01245
uniprot id: E4NSY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

469382:HBOR RS17920
gene id: 469382:HBOR_RS17920
uniprot id: E4NW24
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS14670
gene id: 469382:HBOR_RS14670
uniprot id: E4NU55
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

469382:HBOR RS08910
gene id: 469382:HBOR_RS08910
uniprot id: E4NN06
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

469382:HBOR RS19075
gene id: 469382:HBOR_RS19075
uniprot id: L9UMU3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS12320
gene id: 469382:HBOR_RS12320
uniprot id: E4NSL3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

469382:HBOR RS07845
gene id: 469382:HBOR_RS07845
uniprot id: E4NL41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

469382:HBOR RS04860
gene id: 469382:HBOR_RS04860
uniprot id: E4NPX0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

469382:HBOR RS18215
gene id: 469382:HBOR_RS18215
uniprot id: E4NW85
names: Similarity
messages: Belongs to the RutC family.

469382:HBOR RS04020
gene id: 469382:HBOR_RS04020
uniprot id: E4NNZ8
names: Similarity
messages: Belongs to the SUI1 family.

469382:HBOR RS08970
gene id: 469382:HBOR_RS08970
uniprot id: E4NN92
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

469382:HBOR RS03915
gene id: 469382:HBOR_RS03915
uniprot id: E4NNX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

469382:HBOR RS12635
gene id: 469382:HBOR_RS12635
uniprot id: E4NT73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

469382:HBOR RS02790
gene id: 469382:HBOR_RS02790
uniprot id: E4NMM3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

469382:HBOR RS14910
gene id: 469382:HBOR_RS14910
uniprot id: E4NUA6
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS01520
gene id: 469382:HBOR_RS01520
uniprot id: E4NTH9
names: Similarity
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.

469382:HBOR RS02780
gene id: 469382:HBOR_RS02780
uniprot id: E4NMM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

469382:HBOR RS07810
gene id: 469382:HBOR_RS07810
uniprot id: E4NL33
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

469382:HBOR RS01760
gene id: 469382:HBOR_RS01760
uniprot id: E4NKS2
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS15550
gene id: 469382:HBOR_RS15550
uniprot id: L9ULC5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS11525
gene id: 469382:HBOR_RS11525
uniprot id: E4NRA4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

469382:HBOR RS12860
gene id: 469382:HBOR_RS12860
uniprot id: E4NTB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

469382:HBOR RS01005
gene id: 469382:HBOR_RS01005
uniprot id: E4NST4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

469382:HBOR RS11685
gene id: 469382:HBOR_RS11685
uniprot id: E4NRD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

469382:HBOR RS15140
gene id: 469382:HBOR_RS15140
uniprot id: E4NUF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS04400
gene id: 469382:HBOR_RS04400
uniprot id: E4NPF3
names: Similarity
messages: Belongs to the HypE family.

469382:HBOR RS15200
gene id: 469382:HBOR_RS15200
uniprot id: E4NUG7
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS04525
gene id: 469382:HBOR_RS04525
uniprot id: E4NPQ0
names: Similarity
messages: Belongs to the PspA/IM30 family.

469382:HBOR RS09790
gene id: 469382:HBOR_RS09790
uniprot id: E4NP56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

469382:HBOR RS15390
gene id: 469382:HBOR_RS15390
uniprot id: E4NUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469382:HBOR RS03510
gene id: 469382:HBOR_RS03510
uniprot id: E4NNH2
names: Similarity
messages: Belongs to the Ahb/Nir family.

469382:HBOR RS12080
gene id: 469382:HBOR_RS12080
uniprot id: E4NS11
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS10565
gene id: 469382:HBOR_RS10565
uniprot id: L9UG18
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS12310
gene id: 469382:HBOR_RS12310
uniprot id: E4NSL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

469382:HBOR RS10120
gene id: 469382:HBOR_RS10120
uniprot id: E4NPJ2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

469382:HBOR RS04215
gene id: 469382:HBOR_RS04215
uniprot id: E4NPB6
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS09950
gene id: 469382:HBOR_RS09950
uniprot id: L9UFP0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS14330
gene id: 469382:HBOR_RS14330
uniprot id: E4NMK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

469382:HBOR RS05815
gene id: 469382:HBOR_RS05815
uniprot id: L9V1S4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS17005
gene id: 469382:HBOR_RS17005
uniprot id: E4NV68
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469382:HBOR RS13395
gene id: 469382:HBOR_RS13395
uniprot id: E4NL68
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

469382:HBOR RS06675
gene id: 469382:HBOR_RS06675
uniprot id: E4NSH5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469382:HBOR RS13935
gene id: 469382:HBOR_RS13935
uniprot id: L9V2Z0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS07185
gene id: 469382:HBOR_RS07185
uniprot id: E4NTL1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS01235
gene id: 469382:HBOR_RS01235
uniprot id: E4NSY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

469382:HBOR RS09635
gene id: 469382:HBOR_RS09635
uniprot id: E4NNV1
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

469382:HBOR RS08590
gene id: 469382:HBOR_RS08590
uniprot id: E4NMT9
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

469382:HBOR RS02045
gene id: 469382:HBOR_RS02045
uniprot id: L9URZ5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS01810
gene id: 469382:HBOR_RS01810
uniprot id: E4NKT2
names: Similarity
messages: Belongs to the 2Fe2S plant-type ferredoxin family.

469382:HBOR RS14850
gene id: 469382:HBOR_RS14850
uniprot id: E4NU94
names: Similarity
messages: Belongs to the UPF0047 family.

469382:HBOR RS08345
gene id: 469382:HBOR_RS08345
uniprot id: E4NM93
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

469382:HBOR RS18080
gene id: 469382:HBOR_RS18080
uniprot id: E4NW57
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS13325
gene id: 469382:HBOR_RS13325
uniprot id: E4NL54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

469382:HBOR RS02585
gene id: 469382:HBOR_RS02585
uniprot id: E4NM38
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

469382:HBOR RS08955
gene id: 469382:HBOR_RS08955
uniprot id: E4NN89
names: Similarity
messages: Belongs to the UPF0145 family.

469382:HBOR RS10875
gene id: 469382:HBOR_RS10875
uniprot id: E4NQE1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS06035
gene id: 469382:HBOR_RS06035
uniprot id: E4NRQ2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

469382:HBOR RS01530
gene id: 469382:HBOR_RS01530
uniprot id: E4NTI1
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

469382:HBOR RS08525
gene id: 469382:HBOR_RS08525
uniprot id: E4NMD0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS17585
gene id: 469382:HBOR_RS17585
uniprot id: L9V3E1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS02210
gene id: 469382:HBOR_RS02210
uniprot id: E4NLG6
names: Similarity
messages: Belongs to the PDCD5 family.

469382:HBOR RS04440
gene id: 469382:HBOR_RS04440
uniprot id: E4NPG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

469382:HBOR RS16275
gene id: 469382:HBOR_RS16275
uniprot id: E4NVM5
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS12620
gene id: 469382:HBOR_RS12620
uniprot id: E4NT70
names: Similarity
messages: Belongs to the UPF0284 family.

469382:HBOR RS06015
gene id: 469382:HBOR_RS06015
uniprot id: E4NRP8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

469382:HBOR RS11635
gene id: 469382:HBOR_RS11635
uniprot id: E4NRC7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS06150
gene id: 469382:HBOR_RS06150
uniprot id: E4NRS2
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS07940
gene id: 469382:HBOR_RS07940
uniprot id: E4NLL1
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

469382:HBOR RS03645
gene id: 469382:HBOR_RS03645
uniprot id: E4NNK0
names: Subcellular Location Annotation
messages: Cytoplasm

469382:HBOR RS02775
gene id: 469382:HBOR_RS02775
uniprot id: E4NMM0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

469382:HBOR RS01595
gene id: 469382:HBOR_RS01595
uniprot id: E4NTI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469382:HBOR RS01140
gene id: 469382:HBOR_RS01140
uniprot id: E4NSW1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

469382:HBOR RS01355
gene id: 469382:HBOR_RS01355
uniprot id: L9URT5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

469382:HBOR RS11145
gene id: 469382:HBOR_RS11145
uniprot id: E4NQS2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS04200
gene id: 469382:HBOR_RS04200
uniprot id: E4NPB3
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS18925
gene id: 469382:HBOR_RS18925
uniprot id: E4NWN6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS04035
gene id: 469382:HBOR_RS04035
uniprot id: E4NP02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

469382:HBOR RS07990
gene id: 469382:HBOR_RS07990
uniprot id: E4NLM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

469382:HBOR RS12155
gene id: 469382:HBOR_RS12155
uniprot id: E4NS25
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

469382:HBOR RS18945
gene id: 469382:HBOR_RS18945
uniprot id: E4NWP0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS09205
gene id: 469382:HBOR_RS09205
uniprot id: E4NNE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

469382:HBOR RS08355
gene id: 469382:HBOR_RS08355
uniprot id: E4NM95
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469382:HBOR RS05670
gene id: 469382:HBOR_RS05670
uniprot id: E4NR29
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

469382:HBOR RS13640
gene id: 469382:HBOR_RS13640
uniprot id: E4NLB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

469382:HBOR RS15645
gene id: 469382:HBOR_RS15645
uniprot id: E4NUQ9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

469382:HBOR RS06670
gene id: 469382:HBOR_RS06670
uniprot id: E4NSH4
names: Subcellular Location Annotation
messages: Membrane

469382:HBOR RS12010
gene id: 469382:HBOR_RS12010
uniprot id: E4NRZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

469382:HBOR RS01430
gene id: 469382:HBOR_RS01430
uniprot id: E4NTG0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

469382:HBOR RS04615
gene id: 469382:HBOR_RS04615
uniprot id: E4NPR9
names: Similarity
messages: Belongs to the MoaD family.

469382:HBOR RS05300
gene id: 469382:HBOR_RS05300
uniprot id: E4NQJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

469382:HBOR RS15565
gene id: 469382:HBOR_RS15565
uniprot id: E4NUP3
names: Similarity
messages: Belongs to the peptidase S8 family.

469382:HBOR RS10855
gene id: 469382:HBOR_RS10855
uniprot id: E4NQD7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

469382:HBOR RS04835
gene id: 469382:HBOR_RS04835
uniprot id: E4NPW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

469382:HBOR RS09780
gene id: 469382:HBOR_RS09780
uniprot id: E4NP54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

469382:HBOR RS13825
gene id: 469382:HBOR_RS13825
uniprot id: E4NLV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane