465817:ETA RS18590
gene id: 465817:ETA_RS18590
uniprot id: B2VCB1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS12805
gene id: 465817:ETA_RS12805
uniprot id: B2VBN6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

465817:ETA RS06800
gene id: 465817:ETA_RS06800
uniprot id: B2VJ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

465817:ETA RS09265
gene id: 465817:ETA_RS09265
uniprot id: B2VKP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS18275
gene id: 465817:ETA_RS18275
uniprot id: B2VCH6
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

465817:ETA RS04895
gene id: 465817:ETA_RS04895
uniprot id: B2VD95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

465817:ETA RS17205
gene id: 465817:ETA_RS17205
uniprot id: B2VJW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

465817:ETA RS07890
gene id: 465817:ETA_RS07890
uniprot id: B2VFM2
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

465817:ETA RS17795
gene id: 465817:ETA_RS17795
uniprot id: B2VHE8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

465817:ETA RS17550
gene id: 465817:ETA_RS17550
uniprot id: B2VJR0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS16670
gene id: 465817:ETA_RS16670
uniprot id: B2VKD3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

465817:ETA RS01855
gene id: 465817:ETA_RS01855
uniprot id: B2VI85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

465817:ETA RS06500
gene id: 465817:ETA_RS06500
uniprot id: B2VI18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

465817:ETA RS13385
gene id: 465817:ETA_RS13385
uniprot id: B2VBD7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

465817:ETA RS11165
gene id: 465817:ETA_RS11165
uniprot id: B2VDN2
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS09090
gene id: 465817:ETA_RS09090
uniprot id: B2VKV8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

465817:ETA RS16045
gene id: 465817:ETA_RS16045
uniprot id: B2VCV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

465817:ETA RS06070
gene id: 465817:ETA_RS06070
uniprot id: B2VEB1
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

465817:ETA RS02840
gene id: 465817:ETA_RS02840
uniprot id: B2VGS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465817:ETA RS08520
gene id: 465817:ETA_RS08520
uniprot id: B2VJB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

465817:ETA RS06200
gene id: 465817:ETA_RS06200
uniprot id: B2VE89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

465817:ETA RS10605
gene id: 465817:ETA_RS10605
uniprot id: B2VEH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

465817:ETA RS17860
gene id: 465817:ETA_RS17860
uniprot id: B2VHF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

465817:ETA RS07465
gene id: 465817:ETA_RS07465
uniprot id: B2VIH0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS12440
gene id: 465817:ETA_RS12440
uniprot id: B2VBT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

465817:ETA RS17785
gene id: 465817:ETA_RS17785
uniprot id: B2VHE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

465817:ETA RS15970
gene id: 465817:ETA_RS15970
uniprot id: B2VCW3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

465817:ETA RS12240
gene id: 465817:ETA_RS12240
uniprot id: B2VC12
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

465817:ETA RS03980
gene id: 465817:ETA_RS03980
uniprot id: B2VHA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

465817:ETA RS10775
gene id: 465817:ETA_RS10775
uniprot id: B2VDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

465817:ETA RS15175
gene id: 465817:ETA_RS15175
uniprot id: B2VFS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

465817:ETA RS07485
gene id: 465817:ETA_RS07485
uniprot id: B2VIH4
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS07125
gene id: 465817:ETA_RS07125
uniprot id: B2VIV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

465817:ETA RS12565
gene id: 465817:ETA_RS12565
uniprot id: B2VBT4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

465817:ETA RS14135
gene id: 465817:ETA_RS14135
uniprot id: B2VHN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

465817:ETA RS06405
gene id: 465817:ETA_RS06405
uniprot id: B2VE48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

465817:ETA RS08835
gene id: 465817:ETA_RS08835
uniprot id: B2VJ49
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

465817:ETA RS11230
gene id: 465817:ETA_RS11230
uniprot id: B2VDL0
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

465817:ETA RS02940
gene id: 465817:ETA_RS02940
uniprot id: B2VL34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

465817:ETA RS15795
gene id: 465817:ETA_RS15795
uniprot id: B2VCZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

465817:ETA RS10200
gene id: 465817:ETA_RS10200
uniprot id: B2VEN2
names: Similarity
messages: Belongs to the SufE family.

465817:ETA RS17585
gene id: 465817:ETA_RS17585
uniprot id: B2VJN4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

465817:ETA RS17560
gene id: 465817:ETA_RS17560
uniprot id: B2VJR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

465817:ETA RS10375
gene id: 465817:ETA_RS10375
uniprot id: B2VEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS10000
gene id: 465817:ETA_RS10000
uniprot id: B2VEQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

465817:ETA RS16120
gene id: 465817:ETA_RS16120
uniprot id: B2VL85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

465817:ETA RS16710
gene id: 465817:ETA_RS16710
uniprot id: B2VKA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

465817:ETA RS10310
gene id: 465817:ETA_RS10310
uniprot id: B2VEL4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

465817:ETA RS10550
gene id: 465817:ETA_RS10550
uniprot id: B2VEJ1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS02295
gene id: 465817:ETA_RS02295
uniprot id: B2VFE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

465817:ETA RS16865
gene id: 465817:ETA_RS16865
uniprot id: B2VK94
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

465817:ETA RS01895
gene id: 465817:ETA_RS01895
uniprot id: B2VG82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

465817:ETA RS05470
gene id: 465817:ETA_RS05470
uniprot id: B2VE24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

465817:ETA RS05245
gene id: 465817:ETA_RS05245
uniprot id: B2VD27
names: Similarity
messages: Belongs to the UPF0231 family.

465817:ETA RS02600
gene id: 465817:ETA_RS02600
uniprot id: B2VGW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

465817:ETA RS00295
gene id: 465817:ETA_RS00295
uniprot id: B2VAV2
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

465817:ETA RS06025
gene id: 465817:ETA_RS06025
uniprot id: B2VI47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

465817:ETA RS09165
gene id: 465817:ETA_RS09165
uniprot id: B2VKU2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

465817:ETA RS03070
gene id: 465817:ETA_RS03070
uniprot id: B2VGM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS13805
gene id: 465817:ETA_RS13805
uniprot id: B2VHS4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

465817:ETA RS16915
gene id: 465817:ETA_RS16915
uniprot id: B2VK73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

465817:ETA RS14025
gene id: 465817:ETA_RS14025
uniprot id: B2VHN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

465817:ETA RS05565
gene id: 465817:ETA_RS05565
uniprot id: B2VE18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

465817:ETA RS12795
gene id: 465817:ETA_RS12795
uniprot id: B2VBN4
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS10145
gene id: 465817:ETA_RS10145
uniprot id: B2VEM5
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

465817:ETA RS02080
gene id: 465817:ETA_RS02080
uniprot id: B2VG68
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

465817:ETA RS01480
gene id: 465817:ETA_RS01480
uniprot id: B2VF56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

465817:ETA RS02230
gene id: 465817:ETA_RS02230
uniprot id: B2VI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

465817:ETA RS03505
gene id: 465817:ETA_RS03505
uniprot id: B2VGF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS16965
gene id: 465817:ETA_RS16965
uniprot id: B2VK52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

465817:ETA RS15855
gene id: 465817:ETA_RS15855
uniprot id: B2VD05
names: Similarity
messages: Belongs to the UPF0307 family.

465817:ETA RS09955
gene id: 465817:ETA_RS09955
uniprot id: B2VK14
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS13590
gene id: 465817:ETA_RS13590
uniprot id: B2VHV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

465817:ETA RS18545
gene id: 465817:ETA_RS18545
uniprot id: B2VCC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

465817:ETA RS17400
gene id: 465817:ETA_RS17400
uniprot id: B2VJU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

465817:ETA RS01695
gene id: 465817:ETA_RS01695
uniprot id: B2VGA5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

465817:ETA RS04965
gene id: 465817:ETA_RS04965
uniprot id: B2VD79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

465817:ETA RS07150
gene id: 465817:ETA_RS07150
uniprot id: B2VIN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

465817:ETA RS10745
gene id: 465817:ETA_RS10745
uniprot id: B2VDU0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

465817:ETA RS05590
gene id: 465817:ETA_RS05590
uniprot id: B2VHX9
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

465817:ETA RS11815
gene id: 465817:ETA_RS11815
uniprot id: B2VC76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

465817:ETA RS09600
gene id: 465817:ETA_RS09600
uniprot id: B2VKI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell inner membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.

465817:ETA RS07960
gene id: 465817:ETA_RS07960
uniprot id: B2VFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

465817:ETA RS06805
gene id: 465817:ETA_RS06805
uniprot id: B2VJ05
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

465817:ETA RS14985
gene id: 465817:ETA_RS14985
uniprot id: B2VFU2
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS02050
gene id: 465817:ETA_RS02050
uniprot id: B2VG62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzzB/Cld/Rol family.
messages: Cell inner membrane
messages: Membrane
messages: Modulates the polysaccharide chain length of enterobacterial common antigen (ECA).
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

465817:ETA RS08140
gene id: 465817:ETA_RS08140
uniprot id: B2VFF9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

465817:ETA RS14255
gene id: 465817:ETA_RS14255
uniprot id: B2VHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS02900
gene id: 465817:ETA_RS02900
uniprot id: B2VGP0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

465817:ETA RS07265
gene id: 465817:ETA_RS07265
uniprot id: B2VIM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS11635
gene id: 465817:ETA_RS11635
uniprot id: B2VDE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

465817:ETA RS13720
gene id: 465817:ETA_RS13720
uniprot id: B2VHT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

465817:ETA RS18365
gene id: 465817:ETA_RS18365
uniprot id: B2VCG2
names: Subcellular Location Annotation
messages: Secreted

465817:ETA RS18260
gene id: 465817:ETA_RS18260
uniprot id: B2VCH2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

465817:ETA RS17960
gene id: 465817:ETA_RS17960
uniprot id: B2VJJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

465817:ETA RS13745
gene id: 465817:ETA_RS13745
uniprot id: B2VHU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

465817:ETA RS07910
gene id: 465817:ETA_RS07910
uniprot id: B2VFM6
names: Similarity
messages: Belongs to the UPF0265 family.

465817:ETA RS04610
gene id: 465817:ETA_RS04610
uniprot id: B2VGR0
names: Similarity
messages: Belongs to the threonine synthase family.

465817:ETA RS15415
gene id: 465817:ETA_RS15415
uniprot id: B2VEZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

465817:ETA RS01795
gene id: 465817:ETA_RS01795
uniprot id: B2VG95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

465817:ETA RS13595
gene id: 465817:ETA_RS13595
uniprot id: B2VHV9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

465817:ETA RS11145
gene id: 465817:ETA_RS11145
uniprot id: B2VDM7
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

465817:ETA RS12935
gene id: 465817:ETA_RS12935
uniprot id: B2VBM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

465817:ETA RS15980
gene id: 465817:ETA_RS15980
uniprot id: B2VCW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

465817:ETA RS05100
gene id: 465817:ETA_RS05100
uniprot id: B2VD56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS12985
gene id: 465817:ETA_RS12985
uniprot id: B2VBK4
names: Subcellular Location Annotation
messages: Cytoplasm

465817:ETA RS00710
gene id: 465817:ETA_RS00710
uniprot id: B2VB46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

465817:ETA RS09025
gene id: 465817:ETA_RS09025
uniprot id: B2VKU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

465817:ETA RS01145
gene id: 465817:ETA_RS01145
uniprot id: B2VF99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS05190
gene id: 465817:ETA_RS05190
uniprot id: B2VD40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane

465817:ETA RS14630
gene id: 465817:ETA_RS14630
uniprot id: B2VG15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

465817:ETA RS17080
gene id: 465817:ETA_RS17080
uniprot id: B2VK44
names: Similarity
messages: Belongs to the SlyX family.

465817:ETA RS04660
gene id: 465817:ETA_RS04660
uniprot id: B2VGR5
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

465817:ETA RS12800
gene id: 465817:ETA_RS12800
uniprot id: B2VBN5
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.

465817:ETA RS13530
gene id: 465817:ETA_RS13530
uniprot id: B2VHX3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS06310
gene id: 465817:ETA_RS06310
uniprot id: B2VE66
names: Similarity
messages: Belongs to the GppA/Ppx family.

465817:ETA RS07295
gene id: 465817:ETA_RS07295
uniprot id: B2VIK3
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

465817:ETA RS13410
gene id: 465817:ETA_RS13410
uniprot id: B2VBA8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS00880
gene id: 465817:ETA_RS00880
uniprot id: B2VB61
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

465817:ETA RS04905
gene id: 465817:ETA_RS04905
uniprot id: B2VD67
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

465817:ETA RS12675
gene id: 465817:ETA_RS12675
uniprot id: B2VBS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

465817:ETA RS06040
gene id: 465817:ETA_RS06040
uniprot id: B2VEA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

465817:ETA RS11175
gene id: 465817:ETA_RS11175
uniprot id: B2VDK2
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.

465817:ETA RS04690
gene id: 465817:ETA_RS04690
uniprot id: B2VGP8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

465817:ETA RS16785
gene id: 465817:ETA_RS16785
uniprot id: B2VKB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS14750
gene id: 465817:ETA_RS14750
uniprot id: B2VG07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS06545
gene id: 465817:ETA_RS06545
uniprot id: B2VE34
names: Subcellular Location Annotation
messages: Cytoplasm

465817:ETA RS02670
gene id: 465817:ETA_RS02670
uniprot id: B2VGV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

465817:ETA RS01330
gene id: 465817:ETA_RS01330
uniprot id: B2VF69
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

465817:ETA RS15100
gene id: 465817:ETA_RS15100
uniprot id: B2VFT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

465817:ETA RS13090
gene id: 465817:ETA_RS13090
uniprot id: B2VBJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

465817:ETA RS02655
gene id: 465817:ETA_RS02655
uniprot id: B2VGU7
names: Similarity
messages: Belongs to the glutamate synthase family.

465817:ETA RS11645
gene id: 465817:ETA_RS11645
uniprot id: B2VDE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

465817:ETA RS04705
gene id: 465817:ETA_RS04705
uniprot id: B2VGQ7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

465817:ETA RS07525
gene id: 465817:ETA_RS07525
uniprot id: B2VII2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homomer.

465817:ETA RS07095
gene id: 465817:ETA_RS07095
uniprot id: B2VIV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465817:ETA RS14720
gene id: 465817:ETA_RS14720
uniprot id: B2VG01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

465817:ETA RS15860
gene id: 465817:ETA_RS15860
uniprot id: B2VCY0
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

465817:ETA RS11585
gene id: 465817:ETA_RS11585
uniprot id: B2VDG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

465817:ETA RS08555
gene id: 465817:ETA_RS08555
uniprot id: B2VJ90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS18565
gene id: 465817:ETA_RS18565
uniprot id: B2VCA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

465817:ETA RS05945
gene id: 465817:ETA_RS05945
uniprot id: B2VEC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

465817:ETA RS11195
gene id: 465817:ETA_RS11195
uniprot id: B2VDL7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

465817:ETA RS05595
gene id: 465817:ETA_RS05595
uniprot id: B2VHY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

465817:ETA RS11270
gene id: 465817:ETA_RS11270
uniprot id: B2VIB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

465817:ETA RS16905
gene id: 465817:ETA_RS16905
uniprot id: B2VK71
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

465817:ETA RS12175
gene id: 465817:ETA_RS12175
uniprot id: B2VBZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

465817:ETA RS12415
gene id: 465817:ETA_RS12415
uniprot id: B2VBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

465817:ETA RS17025
gene id: 465817:ETA_RS17025
uniprot id: B2VK65
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

465817:ETA RS02990
gene id: 465817:ETA_RS02990
uniprot id: B2VGM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

465817:ETA RS07250
gene id: 465817:ETA_RS07250
uniprot id: B2VIM5
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

465817:ETA RS16530
gene id: 465817:ETA_RS16530
uniprot id: B2VKE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS03680
gene id: 465817:ETA_RS03680
uniprot id: B2VKY4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.

465817:ETA RS18550
gene id: 465817:ETA_RS18550
uniprot id: B2VCA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

465817:ETA RS07210
gene id: 465817:ETA_RS07210
uniprot id: B2VIL7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

465817:ETA RS12860
gene id: 465817:ETA_RS12860
uniprot id: B2VBL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS11740
gene id: 465817:ETA_RS11740
uniprot id: B2VC95
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

465817:ETA RS11540
gene id: 465817:ETA_RS11540
uniprot id: B2VDG7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465817:ETA RS17810
gene id: 465817:ETA_RS17810
uniprot id: B2VHF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

465817:ETA RS09185
gene id: 465817:ETA_RS09185
uniprot id: B2VKR4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS09890
gene id: 465817:ETA_RS09890
uniprot id: B2VEU6
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS07100
gene id: 465817:ETA_RS07100
uniprot id: B2VIV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465817:ETA RS09870
gene id: 465817:ETA_RS09870
uniprot id: B2VEU2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465817:ETA RS01980
gene id: 465817:ETA_RS01980
uniprot id: B2VI69
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

465817:ETA RS15090
gene id: 465817:ETA_RS15090
uniprot id: B2VFT5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

465817:ETA RS18165
gene id: 465817:ETA_RS18165
uniprot id: B2VCI6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS00405
gene id: 465817:ETA_RS00405
uniprot id: B2VAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

465817:ETA RS04920
gene id: 465817:ETA_RS04920
uniprot id: B2VD75
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

465817:ETA RS06365
gene id: 465817:ETA_RS06365
uniprot id: B2VE77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

465817:ETA RS01885
gene id: 465817:ETA_RS01885
uniprot id: B2VG76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

465817:ETA RS07050
gene id: 465817:ETA_RS07050
uniprot id: B2VIP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS13940
gene id: 465817:ETA_RS13940
uniprot id: B2VIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

465817:ETA RS17115
gene id: 465817:ETA_RS17115
uniprot id: B2VK17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS14120
gene id: 465817:ETA_RS14120
uniprot id: B2VHM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

465817:ETA RS08060
gene id: 465817:ETA_RS08060
uniprot id: B2VFH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS16980
gene id: 465817:ETA_RS16980
uniprot id: B2VK55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

465817:ETA RS03375
gene id: 465817:ETA_RS03375
uniprot id: B2VGH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

465817:ETA RS03360
gene id: 465817:ETA_RS03360
uniprot id: B2VGG0
names: Similarity
messages: Belongs to the group II decarboxylase family.

465817:ETA RS05770
gene id: 465817:ETA_RS05770
uniprot id: B2VDW9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS18480
gene id: 465817:ETA_RS18480
uniprot id: B2VCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS16775
gene id: 465817:ETA_RS16775
uniprot id: B2VKB5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS10300
gene id: 465817:ETA_RS10300
uniprot id: B2VEL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

465817:ETA RS07460
gene id: 465817:ETA_RS07460
uniprot id: B2VIG9
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

465817:ETA RS14700
gene id: 465817:ETA_RS14700
uniprot id: B2VFZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

465817:ETA RS07640
gene id: 465817:ETA_RS07640
uniprot id: B2VFQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

465817:ETA RS01805
gene id: 465817:ETA_RS01805
uniprot id: B2VG97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

465817:ETA RS01610
gene id: 465817:ETA_RS01610
uniprot id: B2VI92
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

465817:ETA RS09895
gene id: 465817:ETA_RS09895
uniprot id: B2VEU8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS02830
gene id: 465817:ETA_RS02830
uniprot id: B2VGT4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

465817:ETA RS09315
gene id: 465817:ETA_RS09315
uniprot id: B2VKQ5
names: Similarity
messages: Belongs to the PspA/IM30 family.

465817:ETA RS07675
gene id: 465817:ETA_RS07675
uniprot id: B2VFR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

465817:ETA RS09260
gene id: 465817:ETA_RS09260
uniprot id: B2VKP5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

465817:ETA RS10455
gene id: 465817:ETA_RS10455
uniprot id: B2VJY8
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

465817:ETA RS17075
gene id: 465817:ETA_RS17075
uniprot id: B2VK43
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

465817:ETA RS11010
gene id: 465817:ETA_RS11010
uniprot id: B2VDR7
names: Similarity
messages: Belongs to the phage antitermination Q type 1 family.

465817:ETA RS06400
gene id: 465817:ETA_RS06400
uniprot id: B2VE62
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS03310
gene id: 465817:ETA_RS03310
uniprot id: B2VGI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

465817:ETA RS10940
gene id: 465817:ETA_RS10940
uniprot id: B2VDR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

465817:ETA RS09620
gene id: 465817:ETA_RS09620
uniprot id: B2VKI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

465817:ETA RS08895
gene id: 465817:ETA_RS08895
uniprot id: B2VJ29
names: Similarity
messages: Belongs to the UPF0229 family.

465817:ETA RS00290
gene id: 465817:ETA_RS00290
uniprot id: B2VAV1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS12510
gene id: 465817:ETA_RS12510
uniprot id: B2VBV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

465817:ETA RS04445
gene id: 465817:ETA_RS04445
uniprot id: B2VH52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

465817:ETA RS12145
gene id: 465817:ETA_RS12145
uniprot id: B2VBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

465817:ETA RS13080
gene id: 465817:ETA_RS13080
uniprot id: B2VBI9
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.

465817:ETA RS07500
gene id: 465817:ETA_RS07500
uniprot id: B2VIH7
names: Similarity
messages: Belongs to the peptidase S8 family.

465817:ETA RS16955
gene id: 465817:ETA_RS16955
uniprot id: B2VK82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

465817:ETA RS18075
gene id: 465817:ETA_RS18075
uniprot id: B2VCK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

465817:ETA RS12640
gene id: 465817:ETA_RS12640
uniprot id: B2VBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

465817:ETA RS07505
gene id: 465817:ETA_RS07505
uniprot id: B2VIH8
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

465817:ETA RS16070
gene id: 465817:ETA_RS16070
uniprot id: B2VCV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

465817:ETA RS02700
gene id: 465817:ETA_RS02700
uniprot id: B2VGV8
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

465817:ETA RS08965
gene id: 465817:ETA_RS08965
uniprot id: B2VKW6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

465817:ETA RS06930
gene id: 465817:ETA_RS06930
uniprot id: B2VIZ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS12910
gene id: 465817:ETA_RS12910
uniprot id: B2VBM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

465817:ETA RS09195
gene id: 465817:ETA_RS09195
uniprot id: B2VKR6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

465817:ETA RS14775
gene id: 465817:ETA_RS14775
uniprot id: B2VFY4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS04525
gene id: 465817:ETA_RS04525
uniprot id: B2VH35
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS01125
gene id: 465817:ETA_RS01125
uniprot id: B2VFA1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS17890
gene id: 465817:ETA_RS17890
uniprot id: B2VHG5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS04755
gene id: 465817:ETA_RS04755
uniprot id: B2VGQ9
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

465817:ETA RS17540
gene id: 465817:ETA_RS17540
uniprot id: B2VJQ8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS11680
gene id: 465817:ETA_RS11680
uniprot id: B2VDF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

465817:ETA RS06900
gene id: 465817:ETA_RS06900
uniprot id: B2VIZ0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

465817:ETA RS13545
gene id: 465817:ETA_RS13545
uniprot id: B2VCL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

465817:ETA RS12635
gene id: 465817:ETA_RS12635
uniprot id: B2VBR1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

465817:ETA RS01195
gene id: 465817:ETA_RS01195
uniprot id: B2VL58
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

465817:ETA RS02665
gene id: 465817:ETA_RS02665
uniprot id: B2VGU8
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

465817:ETA RS14980
gene id: 465817:ETA_RS14980
uniprot id: B2VFU1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

465817:ETA RS09900
gene id: 465817:ETA_RS09900
uniprot id: B2VK03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS10475
gene id: 465817:ETA_RS10475
uniprot id: B2VEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

465817:ETA RS16340
gene id: 465817:ETA_RS16340
uniprot id: B2VCQ6
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

465817:ETA RS07245
gene id: 465817:ETA_RS07245
uniprot id: B2VIM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

465817:ETA RS04730
gene id: 465817:ETA_RS04730
uniprot id: B2VGQ0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

465817:ETA RS02835
gene id: 465817:ETA_RS02835
uniprot id: B2VGT8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

465817:ETA RS01105
gene id: 465817:ETA_RS01105
uniprot id: B2VFC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

465817:ETA RS09400
gene id: 465817:ETA_RS09400
uniprot id: B2VKN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

465817:ETA RS03665
gene id: 465817:ETA_RS03665
uniprot id: B2VKY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

465817:ETA RS07775
gene id: 465817:ETA_RS07775
uniprot id: B2VFM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS00095
gene id: 465817:ETA_RS00095
uniprot id: B2VAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

465817:ETA RS14870
gene id: 465817:ETA_RS14870
uniprot id: B2VFX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

465817:ETA RS06115
gene id: 465817:ETA_RS06115
uniprot id: B2VI24
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS07830
gene id: 465817:ETA_RS07830
uniprot id: B2VFL0
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

465817:ETA RS14760
gene id: 465817:ETA_RS14760
uniprot id: B2VG09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS12700
gene id: 465817:ETA_RS12700
uniprot id: B2VBP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

465817:ETA RS06155
gene id: 465817:ETA_RS06155
uniprot id: B2VI31
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

465817:ETA RS10425
gene id: 465817:ETA_RS10425
uniprot id: B2VJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

465817:ETA RS17280
gene id: 465817:ETA_RS17280
uniprot id: B2VJU8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

465817:ETA RS15155
gene id: 465817:ETA_RS15155
uniprot id: B2VFS0
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

465817:ETA RS09795
gene id: 465817:ETA_RS09795
uniprot id: B2VEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS09115
gene id: 465817:ETA_RS09115
uniprot id: B2VKT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

465817:ETA RS07540
gene id: 465817:ETA_RS07540
uniprot id: B2VIE8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

465817:ETA RS05740
gene id: 465817:ETA_RS05740
uniprot id: B2VDW7
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS11255
gene id: 465817:ETA_RS11255
uniprot id: B2VDL8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

465817:ETA RS17050
gene id: 465817:ETA_RS17050
uniprot id: B2VK38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

465817:ETA RS14820
gene id: 465817:ETA_RS14820
uniprot id: B2VFZ3
names: Subcellular Location Annotation
messages: Cell inner membrane

465817:ETA RS10315
gene id: 465817:ETA_RS10315
uniprot id: B2VEL7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

465817:ETA RS02970
gene id: 465817:ETA_RS02970
uniprot id: B2VL40
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

465817:ETA RS01455
gene id: 465817:ETA_RS01455
uniprot id: B2VL56
names: Subcellular Location Annotation
messages: Cell inner membrane

465817:ETA RS15335
gene id: 465817:ETA_RS15335
uniprot id: B2VF06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

465817:ETA RS08455
gene id: 465817:ETA_RS08455
uniprot id: B2VJA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

465817:ETA RS18520
gene id: 465817:ETA_RS18520
uniprot id: B2VCC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

465817:ETA RS02630
gene id: 465817:ETA_RS02630
uniprot id: B2VGX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

465817:ETA RS11600
gene id: 465817:ETA_RS11600
uniprot id: B2VDH0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

465817:ETA RS11715
gene id: 465817:ETA_RS11715
uniprot id: B2VC90
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS18575
gene id: 465817:ETA_RS18575
uniprot id: B2VCA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

465817:ETA RS06230
gene id: 465817:ETA_RS06230
uniprot id: B2VE96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

465817:ETA RS06160
gene id: 465817:ETA_RS06160
uniprot id: B2VI32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

465817:ETA RS06515
gene id: 465817:ETA_RS06515
uniprot id: B2VE35
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS11700
gene id: 465817:ETA_RS11700
uniprot id: B2VC87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

465817:ETA RS07305
gene id: 465817:ETA_RS07305
uniprot id: B2VIK5
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

465817:ETA RS09915
gene id: 465817:ETA_RS09915
uniprot id: B2VK06
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS11205
gene id: 465817:ETA_RS11205
uniprot id: B2VDK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

465817:ETA RS05785
gene id: 465817:ETA_RS05785
uniprot id: B2VDV1
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

465817:ETA RS01045
gene id: 465817:ETA_RS01045
uniprot id: B2VFB7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS13580
gene id: 465817:ETA_RS13580
uniprot id: B2VHV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465817:ETA RS15270
gene id: 465817:ETA_RS15270
uniprot id: B2VF21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

465817:ETA RS12020
gene id: 465817:ETA_RS12020
uniprot id: B2VC49
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

465817:ETA RS09665
gene id: 465817:ETA_RS09665
uniprot id: B2VKG4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

465817:ETA RS14360
gene id: 465817:ETA_RS14360
uniprot id: B2VIE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0294 family.
messages: Cytoplasm

465817:ETA RS10510
gene id: 465817:ETA_RS10510
uniprot id: B2VEH6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

465817:ETA RS06880
gene id: 465817:ETA_RS06880
uniprot id: B2VIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

465817:ETA RS02035
gene id: 465817:ETA_RS02035
uniprot id: B2VG59
names: Similarity
messages: Belongs to the thioredoxin family.

465817:ETA RS08705
gene id: 465817:ETA_RS08705
uniprot id: B2VJ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

465817:ETA RS15065
gene id: 465817:ETA_RS15065
uniprot id: B2VFT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS05490
gene id: 465817:ETA_RS05490
uniprot id: B2VE28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

465817:ETA RS11245
gene id: 465817:ETA_RS11245
uniprot id: B2VDL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

465817:ETA RS13740
gene id: 465817:ETA_RS13740
uniprot id: B2VHU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

465817:ETA RS12185
gene id: 465817:ETA_RS12185
uniprot id: B2VC01
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

465817:ETA RS05535
gene id: 465817:ETA_RS05535
uniprot id: B2VE10
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS12330
gene id: 465817:ETA_RS12330
uniprot id: B2VBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

465817:ETA RS18145
gene id: 465817:ETA_RS18145
uniprot id: B2VCI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

465817:ETA RS15250
gene id: 465817:ETA_RS15250
uniprot id: B2VF17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

465817:ETA RS06620
gene id: 465817:ETA_RS06620
uniprot id: B2VDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

465817:ETA RS10780
gene id: 465817:ETA_RS10780
uniprot id: B2VDT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 37 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Periplasm
messages: Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.

465817:ETA RS10245
gene id: 465817:ETA_RS10245
uniprot id: B2VK00
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

465817:ETA RS07110
gene id: 465817:ETA_RS07110
uniprot id: B2VIV6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

465817:ETA RS01530
gene id: 465817:ETA_RS01530
uniprot id: B2VER4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

465817:ETA RS09440
gene id: 465817:ETA_RS09440
uniprot id: B2VKL4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS10410
gene id: 465817:ETA_RS10410
uniprot id: B2VJX9
names: Function
names: Similarity
messages: Belongs to the arginine N-succinyltransferase family.
messages: Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.

465817:ETA RS08860
gene id: 465817:ETA_RS08860
uniprot id: B2VJ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

465817:ETA RS05075
gene id: 465817:ETA_RS05075
uniprot id: B2VD64
names: Similarity
messages: Belongs to the Nudix hydrolase family.

465817:ETA RS06350
gene id: 465817:ETA_RS06350
uniprot id: B2VE74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

465817:ETA RS09030
gene id: 465817:ETA_RS09030
uniprot id: B2VKU5
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

465817:ETA RS11385
gene id: 465817:ETA_RS11385
uniprot id: B2VDJ9
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

465817:ETA RS15245
gene id: 465817:ETA_RS15245
uniprot id: B2VF44
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

465817:ETA RS11580
gene id: 465817:ETA_RS11580
uniprot id: B2VDG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmI family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.

465817:ETA RS12880
gene id: 465817:ETA_RS12880
uniprot id: B2VBL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS06550
gene id: 465817:ETA_RS06550
uniprot id: B2VE37
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

465817:ETA RS08125
gene id: 465817:ETA_RS08125
uniprot id: B2VFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

465817:ETA RS09875
gene id: 465817:ETA_RS09875
uniprot id: B2VEU3
names: Similarity
messages: Belongs to the UPF0482 family.

465817:ETA RS13905
gene id: 465817:ETA_RS13905
uniprot id: B2VHR4
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

465817:ETA RS11420
gene id: 465817:ETA_RS11420
uniprot id: B2VDH4
names: Function
names: Similarity
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsC sub-subfamily.
messages: Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE).

465817:ETA RS11800
gene id: 465817:ETA_RS11800
uniprot id: B2VC73
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

465817:ETA RS13000
gene id: 465817:ETA_RS13000
uniprot id: B2VBK7
names: Similarity
messages: Belongs to the hyi family.

465817:ETA RS08390
gene id: 465817:ETA_RS08390
uniprot id: B2VJC7
names: Similarity
messages: Belongs to the peptidase S24 family.

465817:ETA RS02640
gene id: 465817:ETA_RS02640
uniprot id: B2VGV0
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

465817:ETA RS09905
gene id: 465817:ETA_RS09905
uniprot id: B2VK04
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

465817:ETA RS01890
gene id: 465817:ETA_RS01890
uniprot id: B2VG77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS13715
gene id: 465817:ETA_RS13715
uniprot id: B2VHT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

465817:ETA RS10850
gene id: 465817:ETA_RS10850
uniprot id: B2VDS2
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

465817:ETA RS08745
gene id: 465817:ETA_RS08745
uniprot id: B2VJ64
names: Similarity
messages: Belongs to the UPF0053 family.

465817:ETA RS03290
gene id: 465817:ETA_RS03290
uniprot id: B2VGH6
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Homodimer.

465817:ETA RS02550
gene id: 465817:ETA_RS02550
uniprot id: B2VGX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

465817:ETA RS03470
gene id: 465817:ETA_RS03470
uniprot id: B2VGF1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS03670
gene id: 465817:ETA_RS03670
uniprot id: B2VKY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

465817:ETA RS16360
gene id: 465817:ETA_RS16360
uniprot id: B2VCR2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465817:ETA RS01570
gene id: 465817:ETA_RS01570
uniprot id: B2VES3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

465817:ETA RS16010
gene id: 465817:ETA_RS16010
uniprot id: B2VCX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

465817:ETA RS14800
gene id: 465817:ETA_RS14800
uniprot id: B2VFY9
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

465817:ETA RS17430
gene id: 465817:ETA_RS17430
uniprot id: B2VJR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

465817:ETA RS04710
gene id: 465817:ETA_RS04710
uniprot id: B2VGQ8
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

465817:ETA RS12170
gene id: 465817:ETA_RS12170
uniprot id: B2VBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

465817:ETA RS10530
gene id: 465817:ETA_RS10530
uniprot id: B2VEI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

465817:ETA RS06975
gene id: 465817:ETA_RS06975
uniprot id: B2VIW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

465817:ETA RS04850
gene id: 465817:ETA_RS04850
uniprot id: B2VD85
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS04145
gene id: 465817:ETA_RS04145
uniprot id: B2VH73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

465817:ETA RS07515
gene id: 465817:ETA_RS07515
uniprot id: B2VII0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS17175
gene id: 465817:ETA_RS17175
uniprot id: B2VK29
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

465817:ETA RS02070
gene id: 465817:ETA_RS02070
uniprot id: B2VG66
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

465817:ETA RS18120
gene id: 465817:ETA_RS18120
uniprot id: B2VCL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

465817:ETA RS13895
gene id: 465817:ETA_RS13895
uniprot id: B2VHR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

465817:ETA RS11475
gene id: 465817:ETA_RS11475
uniprot id: B2VI99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

465817:ETA RS17040
gene id: 465817:ETA_RS17040
uniprot id: B2VK36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

465817:ETA RS02650
gene id: 465817:ETA_RS02650
uniprot id: B2VGU6
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

465817:ETA RS07030
gene id: 465817:ETA_RS07030
uniprot id: B2VIX7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

465817:ETA RS18585
gene id: 465817:ETA_RS18585
uniprot id: B2VCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

465817:ETA RS03120
gene id: 465817:ETA_RS03120
uniprot id: B2VGL2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465817:ETA RS11425
gene id: 465817:ETA_RS11425
uniprot id: B2VDH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS09470
gene id: 465817:ETA_RS09470
uniprot id: B2VKM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

465817:ETA RS09630
gene id: 465817:ETA_RS09630
uniprot id: B2VKI8
names: Similarity
messages: Belongs to the barstar family.

465817:ETA RS04460
gene id: 465817:ETA_RS04460
uniprot id: B2VH26
names: Similarity
messages: Belongs to the Smp family.

465817:ETA RS07780
gene id: 465817:ETA_RS07780
uniprot id: B2VFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

465817:ETA RS17445
gene id: 465817:ETA_RS17445
uniprot id: B2VJR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS18560
gene id: 465817:ETA_RS18560
uniprot id: B2VCA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

465817:ETA RS01675
gene id: 465817:ETA_RS01675
uniprot id: B2VG99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS08185
gene id: 465817:ETA_RS08185
uniprot id: B2VFG6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

465817:ETA RS05060
gene id: 465817:ETA_RS05060
uniprot id: B2VI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS09140
gene id: 465817:ETA_RS09140
uniprot id: B2VKT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

465817:ETA RS11810
gene id: 465817:ETA_RS11810
uniprot id: B2VC75
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS07950
gene id: 465817:ETA_RS07950
uniprot id: B2VFK5
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

465817:ETA RS11030
gene id: 465817:ETA_RS11030
uniprot id: B2VDN8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

465817:ETA RS12930
gene id: 465817:ETA_RS12930
uniprot id: B2VBM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

465817:ETA RS15025
gene id: 465817:ETA_RS15025
uniprot id: B2VFV0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

465817:ETA RS12480
gene id: 465817:ETA_RS12480
uniprot id: B2VBU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

465817:ETA RS13400
gene id: 465817:ETA_RS13400
uniprot id: B2VBE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

465817:ETA RS17260
gene id: 465817:ETA_RS17260
uniprot id: B2VJX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

465817:ETA RS08250
gene id: 465817:ETA_RS08250
uniprot id: B2VFE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

465817:ETA RS15725
gene id: 465817:ETA_RS15725
uniprot id: B2VDB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

465817:ETA RS06645
gene id: 465817:ETA_RS06645
uniprot id: B2VDY8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

465817:ETA RS05970
gene id: 465817:ETA_RS05970
uniprot id: B2VI36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

465817:ETA RS12685
gene id: 465817:ETA_RS12685
uniprot id: B2VBS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

465817:ETA RS17995
gene id: 465817:ETA_RS17995
uniprot id: B2VJK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

465817:ETA RS08535
gene id: 465817:ETA_RS08535
uniprot id: B2VJC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

465817:ETA RS09325
gene id: 465817:ETA_RS09325
uniprot id: B2VKQ7
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS02005
gene id: 465817:ETA_RS02005
uniprot id: B2VI74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS17670
gene id: 465817:ETA_RS17670
uniprot id: B2VJL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

465817:ETA RS15785
gene id: 465817:ETA_RS15785
uniprot id: B2VDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LpoA family.
messages: Cell outer membrane
messages: Interacts with PBP1a.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).

465817:ETA RS08765
gene id: 465817:ETA_RS08765
uniprot id: B2VJ68
names: Similarity
messages: Belongs to the UPF0181 family.

465817:ETA RS17220
gene id: 465817:ETA_RS17220
uniprot id: B2VJW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

465817:ETA RS06030
gene id: 465817:ETA_RS06030
uniprot id: B2VI48
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

465817:ETA RS04865
gene id: 465817:ETA_RS04865
uniprot id: B2VD89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

465817:ETA RS06180
gene id: 465817:ETA_RS06180
uniprot id: B2VE97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

465817:ETA RS07755
gene id: 465817:ETA_RS07755
uniprot id: B2VFQ0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

465817:ETA RS14665
gene id: 465817:ETA_RS14665
uniprot id: B2VG22
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

465817:ETA RS02540
gene id: 465817:ETA_RS02540
uniprot id: B2VGY3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

465817:ETA RS18175
gene id: 465817:ETA_RS18175
uniprot id: B2VCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

465817:ETA RS05850
gene id: 465817:ETA_RS05850
uniprot id: B2VEE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

465817:ETA RS11660
gene id: 465817:ETA_RS11660
uniprot id: B2VDF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

465817:ETA RS01305
gene id: 465817:ETA_RS01305
uniprot id: B2VF78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

465817:ETA RS15955
gene id: 465817:ETA_RS15955
uniprot id: B2VCW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

465817:ETA RS02580
gene id: 465817:ETA_RS02580
uniprot id: B2VGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Forms an efflux pump with AaeB.

465817:ETA RS17120
gene id: 465817:ETA_RS17120
uniprot id: B2VK18
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS19515
gene id: 465817:ETA_RS19515
uniprot id: B2VCE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

465817:ETA RS12425
gene id: 465817:ETA_RS12425
uniprot id: B2VBX0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS10735
gene id: 465817:ETA_RS10735
uniprot id: B2VIE4
names: Subcellular Location Annotation
messages: Cytoplasm

465817:ETA RS13910
gene id: 465817:ETA_RS13910
uniprot id: B2VHR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

465817:ETA RS08095
gene id: 465817:ETA_RS08095
uniprot id: B2VFH9
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS07575
gene id: 465817:ETA_RS07575
uniprot id: B2VIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane

465817:ETA RS12260
gene id: 465817:ETA_RS12260
uniprot id: B2VBX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

465817:ETA RS16475
gene id: 465817:ETA_RS16475
uniprot id: B2VKF7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS05560
gene id: 465817:ETA_RS05560
uniprot id: B2VE15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

465817:ETA RS11210
gene id: 465817:ETA_RS11210
uniprot id: B2VDK6
names: Similarity
messages: Belongs to the fabD family.

465817:ETA RS12045
gene id: 465817:ETA_RS12045
uniprot id: B2VC14
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

465817:ETA RS02565
gene id: 465817:ETA_RS02565
uniprot id: B2VGW9
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Probable metalloprotease.

465817:ETA RS18490
gene id: 465817:ETA_RS18490
uniprot id: B2VCB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

465817:ETA RS05020
gene id: 465817:ETA_RS05020
uniprot id: B2VI00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS02520
gene id: 465817:ETA_RS02520
uniprot id: B2VGX7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

465817:ETA RS09975
gene id: 465817:ETA_RS09975
uniprot id: B2VER0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.
messages: Homohexamer.

465817:ETA RS15345
gene id: 465817:ETA_RS15345
uniprot id: B2VF08
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

465817:ETA RS11170
gene id: 465817:ETA_RS11170
uniprot id: B2VDN3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

465817:ETA RS13500
gene id: 465817:ETA_RS13500
uniprot id: B2VHX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

465817:ETA RS03240
gene id: 465817:ETA_RS03240
uniprot id: B2VGJ5
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS09340
gene id: 465817:ETA_RS09340
uniprot id: B2VKR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane

465817:ETA RS09655
gene id: 465817:ETA_RS09655
uniprot id: B2VKJ3
names: Similarity
messages: Belongs to the MQO family.

465817:ETA RS09735
gene id: 465817:ETA_RS09735
uniprot id: B2VKH8
names: Similarity
messages: Belongs to the catalase family.

465817:ETA RS10625
gene id: 465817:ETA_RS10625
uniprot id: B2VEE9
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body

465817:ETA RS11040
gene id: 465817:ETA_RS11040
uniprot id: B2VDP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

465817:ETA RS11265
gene id: 465817:ETA_RS11265
uniprot id: B2VIB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

465817:ETA RS04390
gene id: 465817:ETA_RS04390
uniprot id: B2VH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

465817:ETA RS16940
gene id: 465817:ETA_RS16940
uniprot id: B2VK79
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

465817:ETA RS12695
gene id: 465817:ETA_RS12695
uniprot id: B2VBS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

465817:ETA RS17055
gene id: 465817:ETA_RS17055
uniprot id: B2VK39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

465817:ETA RS07005
gene id: 465817:ETA_RS07005
uniprot id: B2VIX2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

465817:ETA RS16350
gene id: 465817:ETA_RS16350
uniprot id: B2VCR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS14540
gene id: 465817:ETA_RS14540
uniprot id: B2VHD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

465817:ETA RS19470
gene id: 465817:ETA_RS19470
uniprot id: B2VK75
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

465817:ETA RS03210
gene id: 465817:ETA_RS03210
uniprot id: B2VGJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

465817:ETA RS04985
gene id: 465817:ETA_RS04985
uniprot id: B2VHZ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465817:ETA RS16335
gene id: 465817:ETA_RS16335
uniprot id: B2VCR4
names: Similarity
messages: Belongs to the group II decarboxylase family.

465817:ETA RS00990
gene id: 465817:ETA_RS00990
uniprot id: B2VFC7
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

465817:ETA RS04035
gene id: 465817:ETA_RS04035
uniprot id: B2VJG2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

465817:ETA RS16535
gene id: 465817:ETA_RS16535
uniprot id: B2VKE2
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.

465817:ETA RS13815
gene id: 465817:ETA_RS13815
uniprot id: B2VHS8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

465817:ETA RS11055
gene id: 465817:ETA_RS11055
uniprot id: B2VDP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

465817:ETA RS02535
gene id: 465817:ETA_RS02535
uniprot id: B2VGY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

465817:ETA RS17610
gene id: 465817:ETA_RS17610
uniprot id: B2VJN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

465817:ETA RS13855
gene id: 465817:ETA_RS13855
uniprot id: B2VHR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS04760
gene id: 465817:ETA_RS04760
uniprot id: B2VDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

465817:ETA RS10220
gene id: 465817:ETA_RS10220
uniprot id: B2VJZ5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

465817:ETA RS02325
gene id: 465817:ETA_RS02325
uniprot id: B2VFE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

465817:ETA RS06885
gene id: 465817:ETA_RS06885
uniprot id: B2VIY7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

465817:ETA RS08440
gene id: 465817:ETA_RS08440
uniprot id: B2VJD7
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

465817:ETA RS17950
gene id: 465817:ETA_RS17950
uniprot id: B2VHH9
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

465817:ETA RS12730
gene id: 465817:ETA_RS12730
uniprot id: B2VBP7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

465817:ETA RS03250
gene id: 465817:ETA_RS03250
uniprot id: B2VGJ8
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

465817:ETA RS08855
gene id: 465817:ETA_RS08855
uniprot id: B2VJ53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

465817:ETA RS08450
gene id: 465817:ETA_RS08450
uniprot id: B2VJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

465817:ETA RS13860
gene id: 465817:ETA_RS13860
uniprot id: B2VHQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

465817:ETA RS14705
gene id: 465817:ETA_RS14705
uniprot id: B2VFZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

465817:ETA RS16015
gene id: 465817:ETA_RS16015
uniprot id: B2VCX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

465817:ETA RS06530
gene id: 465817:ETA_RS06530
uniprot id: B2VE44
names: Subcellular Location Annotation
messages: Cell inner membrane

465817:ETA RS09725
gene id: 465817:ETA_RS09725
uniprot id: B2VKH6
names: Similarity
messages: Belongs to the CmpA/NrtA family.

465817:ETA RS07045
gene id: 465817:ETA_RS07045
uniprot id: B2VIP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

465817:ETA RS01090
gene id: 465817:ETA_RS01090
uniprot id: B2VFB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

465817:ETA RS08270
gene id: 465817:ETA_RS08270
uniprot id: B2VFF2
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

465817:ETA RS06990
gene id: 465817:ETA_RS06990
uniprot id: B2VIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS09995
gene id: 465817:ETA_RS09995
uniprot id: B2VEQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

465817:ETA RS05580
gene id: 465817:ETA_RS05580
uniprot id: B2VHX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

465817:ETA RS13485
gene id: 465817:ETA_RS13485
uniprot id: B2VHW6
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS17225
gene id: 465817:ETA_RS17225
uniprot id: B2VJW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

465817:ETA RS03475
gene id: 465817:ETA_RS03475
uniprot id: B2VGF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

465817:ETA RS11045
gene id: 465817:ETA_RS11045
uniprot id: B2VDP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

465817:ETA RS01735
gene id: 465817:ETA_RS01735
uniprot id: B2VG87
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

465817:ETA RS01740
gene id: 465817:ETA_RS01740
uniprot id: B2VG89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

465817:ETA RS04435
gene id: 465817:ETA_RS04435
uniprot id: B2VH50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

465817:ETA RS10125
gene id: 465817:ETA_RS10125
uniprot id: B2VEP8
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

465817:ETA RS12970
gene id: 465817:ETA_RS12970
uniprot id: B2VBK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

465817:ETA RS11685
gene id: 465817:ETA_RS11685
uniprot id: B2VC84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

465817:ETA RS08400
gene id: 465817:ETA_RS08400
uniprot id: B2VJC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS14955
gene id: 465817:ETA_RS14955
uniprot id: B2VFW3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

465817:ETA RS01765
gene id: 465817:ETA_RS01765
uniprot id: B2VG88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

465817:ETA RS06440
gene id: 465817:ETA_RS06440
uniprot id: B2VE58
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465817:ETA RS05955
gene id: 465817:ETA_RS05955
uniprot id: B2VEC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

465817:ETA RS09500
gene id: 465817:ETA_RS09500
uniprot id: B2VKM7
names: Subcellular Location Annotation
messages: Cell inner membrane

465817:ETA RS07945
gene id: 465817:ETA_RS07945
uniprot id: B2VFK4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

465817:ETA RS06085
gene id: 465817:ETA_RS06085
uniprot id: B2VEB4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

465817:ETA RS03510
gene id: 465817:ETA_RS03510
uniprot id: B2VKZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS01920
gene id: 465817:ETA_RS01920
uniprot id: B2VG81
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

465817:ETA RS18330
gene id: 465817:ETA_RS18330
uniprot id: B2VCF5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

465817:ETA RS11310
gene id: 465817:ETA_RS11310
uniprot id: B2VIB9
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

465817:ETA RS10980
gene id: 465817:ETA_RS10980
uniprot id: B2VDQ9
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

465817:ETA RS07705
gene id: 465817:ETA_RS07705
uniprot id: B2VFP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS19320
gene id: 465817:ETA_RS19320
uniprot id: B2VBU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell inner membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

465817:ETA RS04770
gene id: 465817:ETA_RS04770
uniprot id: B2VD97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

465817:ETA RS17935
gene id: 465817:ETA_RS17935
uniprot id: B2VHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

465817:ETA RS13010
gene id: 465817:ETA_RS13010
uniprot id: B2VBK9
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

465817:ETA RS13775
gene id: 465817:ETA_RS13775
uniprot id: B2VHT0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

465817:ETA RS15620
gene id: 465817:ETA_RS15620
uniprot id: B2VL09
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. It is thought that this protein is a protease that cleaves peptides bond in a small peptide (gene pqqA), providing the glutamate and tyrosine residues which are necessary for the synthesis of PQQ.

465817:ETA RS17525
gene id: 465817:ETA_RS17525
uniprot id: B2VJQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS01040
gene id: 465817:ETA_RS01040
uniprot id: B2VFB6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS07840
gene id: 465817:ETA_RS07840
uniprot id: B2VFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

465817:ETA RS04885
gene id: 465817:ETA_RS04885
uniprot id: B2VD93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

465817:ETA RS16755
gene id: 465817:ETA_RS16755
uniprot id: B2VKB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

465817:ETA RS13675
gene id: 465817:ETA_RS13675
uniprot id: B2VIU5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

465817:ETA RS02255
gene id: 465817:ETA_RS02255
uniprot id: B2VG41
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

465817:ETA RS10010
gene id: 465817:ETA_RS10010
uniprot id: B2VEQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

465817:ETA RS01650
gene id: 465817:ETA_RS01650
uniprot id: B2VGA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M20A family. ArgE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS04310
gene id: 465817:ETA_RS04310
uniprot id: B2VH62
names: Similarity
messages: Belongs to the VgrG protein family.

465817:ETA RS00085
gene id: 465817:ETA_RS00085
uniprot id: B2VAS6
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS10290
gene id: 465817:ETA_RS10290
uniprot id: B2VEL9
names: Similarity
messages: Belongs to the peptidase C40 family.

465817:ETA RS01110
gene id: 465817:ETA_RS01110
uniprot id: B2VFC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

465817:ETA RS07240
gene id: 465817:ETA_RS07240
uniprot id: B2VIM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

465817:ETA RS09100
gene id: 465817:ETA_RS09100
uniprot id: B2VKW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS17565
gene id: 465817:ETA_RS17565
uniprot id: B2VJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

465817:ETA RS11865
gene id: 465817:ETA_RS11865
uniprot id: B2VC54
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465817:ETA RS16380
gene id: 465817:ETA_RS16380
uniprot id: B2VCN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

465817:ETA RS09050
gene id: 465817:ETA_RS09050
uniprot id: B2VKU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

465817:ETA RS11835
gene id: 465817:ETA_RS11835
uniprot id: B2VC80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS09625
gene id: 465817:ETA_RS09625
uniprot id: B2VKI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

465817:ETA RS09910
gene id: 465817:ETA_RS09910
uniprot id: B2VK05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS08055
gene id: 465817:ETA_RS08055
uniprot id: B2VFH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS07990
gene id: 465817:ETA_RS07990
uniprot id: B2VFI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

465817:ETA RS12515
gene id: 465817:ETA_RS12515
uniprot id: B2VBS5
names: Similarity
messages: Belongs to the aldose epimerase family.

465817:ETA RS17765
gene id: 465817:ETA_RS17765
uniprot id: B2VHE2
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS06385
gene id: 465817:ETA_RS06385
uniprot id: B2VE56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

465817:ETA RS07495
gene id: 465817:ETA_RS07495
uniprot id: B2VIH6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS05600
gene id: 465817:ETA_RS05600
uniprot id: B2VHY1
names: Subcellular Location Annotation
messages: Cytoplasm

465817:ETA RS15635
gene id: 465817:ETA_RS15635
uniprot id: B2VL12
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

465817:ETA RS03140
gene id: 465817:ETA_RS03140
uniprot id: B2VL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS15290
gene id: 465817:ETA_RS15290
uniprot id: B2VF25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

465817:ETA RS04740
gene id: 465817:ETA_RS04740
uniprot id: B2VGQ2
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

465817:ETA RS00345
gene id: 465817:ETA_RS00345
uniprot id: B2VAW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

465817:ETA RS16075
gene id: 465817:ETA_RS16075
uniprot id: B2VCV2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

465817:ETA RS12165
gene id: 465817:ETA_RS12165
uniprot id: B2VBZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS01210
gene id: 465817:ETA_RS01210
uniprot id: B2VL61
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
messages: Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.

465817:ETA RS16560
gene id: 465817:ETA_RS16560
uniprot id: B2VKE7
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS01495
gene id: 465817:ETA_RS01495
uniprot id: B2VF61
names: Similarity
messages: Belongs to the PhzF family.

465817:ETA RS12625
gene id: 465817:ETA_RS12625
uniprot id: B2VBQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

465817:ETA RS09455
gene id: 465817:ETA_RS09455
uniprot id: B2VKL7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

465817:ETA RS14425
gene id: 465817:ETA_RS14425
uniprot id: B2VHE0
names: Subcellular Location Annotation
messages: Cytoplasm

465817:ETA RS18555
gene id: 465817:ETA_RS18555
uniprot id: B2VCA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

465817:ETA RS14250
gene id: 465817:ETA_RS14250
uniprot id: B2VHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS15120
gene id: 465817:ETA_RS15120
uniprot id: B2VF45
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS11975
gene id: 465817:ETA_RS11975
uniprot id: B2VC40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

465817:ETA RS07285
gene id: 465817:ETA_RS07285
uniprot id: B2VIK0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

465817:ETA RS11090
gene id: 465817:ETA_RS11090
uniprot id: B2VDQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

465817:ETA RS07850
gene id: 465817:ETA_RS07850
uniprot id: B2VFL4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

465817:ETA RS10620
gene id: 465817:ETA_RS10620
uniprot id: B2VEH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

465817:ETA RS05585
gene id: 465817:ETA_RS05585
uniprot id: B2VHX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

465817:ETA RS09930
gene id: 465817:ETA_RS09930
uniprot id: B2VK09
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

465817:ETA RS06290
gene id: 465817:ETA_RS06290
uniprot id: B2VE80
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS13635
gene id: 465817:ETA_RS13635
uniprot id: B2VIT6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

465817:ETA RS03715
gene id: 465817:ETA_RS03715
uniprot id: B2VGB1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465817:ETA RS11705
gene id: 465817:ETA_RS11705
uniprot id: B2VC88
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.
messages: FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.
messages: Homotetramer.

465817:ETA RS00770
gene id: 465817:ETA_RS00770
uniprot id: B2VB99
names: Similarity
messages: Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family.

465817:ETA RS01020
gene id: 465817:ETA_RS01020
uniprot id: B2VFD4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS01025
gene id: 465817:ETA_RS01025
uniprot id: B2VFD5
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

465817:ETA RS03480
gene id: 465817:ETA_RS03480
uniprot id: B2VGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

465817:ETA RS02735
gene id: 465817:ETA_RS02735
uniprot id: B2VGU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

465817:ETA RS10140
gene id: 465817:ETA_RS10140
uniprot id: B2VEM4
names: Similarity
messages: Belongs to the peptidase C40 family.

465817:ETA RS13790
gene id: 465817:ETA_RS13790
uniprot id: B2VHS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

465817:ETA RS03460
gene id: 465817:ETA_RS03460
uniprot id: B2VGE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

465817:ETA RS07560
gene id: 465817:ETA_RS07560
uniprot id: B2VIF2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

465817:ETA RS15200
gene id: 465817:ETA_RS15200
uniprot id: B2VF35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

465817:ETA RS06360
gene id: 465817:ETA_RS06360
uniprot id: B2VE76
names: Similarity
messages: Belongs to the ArsC family.

465817:ETA RS16140
gene id: 465817:ETA_RS16140
uniprot id: B2VL89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

465817:ETA RS09095
gene id: 465817:ETA_RS09095
uniprot id: B2VKV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

465817:ETA RS05090
gene id: 465817:ETA_RS05090
uniprot id: B2VD54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

465817:ETA RS01230
gene id: 465817:ETA_RS01230
uniprot id: B2VF95
names: Similarity
messages: Belongs to the YjdM family.

465817:ETA RS08615
gene id: 465817:ETA_RS08615
uniprot id: B2VJA2
names: Similarity
messages: Belongs to the pyruvate kinase family.

465817:ETA RS14330
gene id: 465817:ETA_RS14330
uniprot id: B2VHJ2
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

465817:ETA RS01450
gene id: 465817:ETA_RS01450
uniprot id: B2VL55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

465817:ETA RS13445
gene id: 465817:ETA_RS13445
uniprot id: B2VBB6
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS13075
gene id: 465817:ETA_RS13075
uniprot id: B2VBI8
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

465817:ETA RS08575
gene id: 465817:ETA_RS08575
uniprot id: B2VJ94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

465817:ETA RS06020
gene id: 465817:ETA_RS06020
uniprot id: B2VI46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

465817:ETA RS04800
gene id: 465817:ETA_RS04800
uniprot id: B2VDA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

465817:ETA RS14685
gene id: 465817:ETA_RS14685
uniprot id: B2VG26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

465817:ETA RS14730
gene id: 465817:ETA_RS14730
uniprot id: B2VG03
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

465817:ETA RS08410
gene id: 465817:ETA_RS08410
uniprot id: B2VJD1
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

465817:ETA RS08805
gene id: 465817:ETA_RS08805
uniprot id: B2VJ43
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

465817:ETA RS06090
gene id: 465817:ETA_RS06090
uniprot id: B2VEB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

465817:ETA RS18470
gene id: 465817:ETA_RS18470
uniprot id: B2VCE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

465817:ETA RS01130
gene id: 465817:ETA_RS01130
uniprot id: B2VFA4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

465817:ETA RS11610
gene id: 465817:ETA_RS11610
uniprot id: B2VDF2
names: Subcellular Location Annotation
messages: Cell inner membrane

465817:ETA RS17065
gene id: 465817:ETA_RS17065
uniprot id: B2VK41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

465817:ETA RS07470
gene id: 465817:ETA_RS07470
uniprot id: B2VIH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

465817:ETA RS13555
gene id: 465817:ETA_RS13555
uniprot id: B2VHU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS09960
gene id: 465817:ETA_RS09960
uniprot id: B2VK15
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS06210
gene id: 465817:ETA_RS06210
uniprot id: B2VE91
names: Similarity
messages: Belongs to the YfgM family.

465817:ETA RS09830
gene id: 465817:ETA_RS09830
uniprot id: B2VET7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

465817:ETA RS04745
gene id: 465817:ETA_RS04745
uniprot id: B2VGQ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

465817:ETA RS18215
gene id: 465817:ETA_RS18215
uniprot id: B2VCJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

465817:ETA RS05360
gene id: 465817:ETA_RS05360
uniprot id: B2VD18
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

465817:ETA RS10225
gene id: 465817:ETA_RS10225
uniprot id: B2VJZ6
names: Similarity
messages: Belongs to the HesB/IscA family.

465817:ETA RS15010
gene id: 465817:ETA_RS15010
uniprot id: B2VFU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS01655
gene id: 465817:ETA_RS01655
uniprot id: B2VGA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS02020
gene id: 465817:ETA_RS02020
uniprot id: B2VG71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

465817:ETA RS11260
gene id: 465817:ETA_RS11260
uniprot id: B2VIA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

465817:ETA RS15015
gene id: 465817:ETA_RS15015
uniprot id: B2VFU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

465817:ETA RS01515
gene id: 465817:ETA_RS01515
uniprot id: B2VF53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

465817:ETA RS15350
gene id: 465817:ETA_RS15350
uniprot id: B2VF09
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

465817:ETA RS06815
gene id: 465817:ETA_RS06815
uniprot id: B2VJ07
names: Similarity
messages: Belongs to the MlaA family.

465817:ETA RS15230
gene id: 465817:ETA_RS15230
uniprot id: B2VF41
names: Similarity
messages: Belongs to the UPF0149 family.

465817:ETA RS05255
gene id: 465817:ETA_RS05255
uniprot id: B2VD21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cytoplasm
messages: Homodimer or homotetramer.

465817:ETA RS04465
gene id: 465817:ETA_RS04465
uniprot id: B2VH21
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

465817:ETA RS02025
gene id: 465817:ETA_RS02025
uniprot id: B2VG72
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

465817:ETA RS19230
gene id: 465817:ETA_RS19230
uniprot id: B2VKX1
names: Similarity
messages: Belongs to the UPF0225 family.

465817:ETA RS03225
gene id: 465817:ETA_RS03225
uniprot id: B2VGJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

465817:ETA RS18415
gene id: 465817:ETA_RS18415
uniprot id: B2VCD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

465817:ETA RS14695
gene id: 465817:ETA_RS14695
uniprot id: B2VFZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

465817:ETA RS15080
gene id: 465817:ETA_RS15080
uniprot id: B2VFT3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465817:ETA RS09820
gene id: 465817:ETA_RS09820
uniprot id: B2VEW3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

465817:ETA RS14000
gene id: 465817:ETA_RS14000
uniprot id: B2VHP4
names: Subcellular Location Annotation
messages: Cytoplasm

465817:ETA RS14410
gene id: 465817:ETA_RS14410
uniprot id: B2VIQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

465817:ETA RS11095
gene id: 465817:ETA_RS11095
uniprot id: B2VDQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

465817:ETA RS12960
gene id: 465817:ETA_RS12960
uniprot id: B2VBJ9
names: Similarity
messages: Belongs to the UPF0250 family.

465817:ETA RS08220
gene id: 465817:ETA_RS08220
uniprot id: B2VES5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

465817:ETA RS08755
gene id: 465817:ETA_RS08755
uniprot id: B2VJ66
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

465817:ETA RS05335
gene id: 465817:ETA_RS05335
uniprot id: B2VD12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

465817:ETA RS08710
gene id: 465817:ETA_RS08710
uniprot id: B2VJ56
names: Similarity
messages: Belongs to the peptidase S41A family.

465817:ETA RS02375
gene id: 465817:ETA_RS02375
uniprot id: B2VGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS15355
gene id: 465817:ETA_RS15355
uniprot id: B2VF10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

465817:ETA RS02795
gene id: 465817:ETA_RS02795
uniprot id: B2VGT6
names: Subcellular Location Annotation
messages: Cell inner membrane

465817:ETA RS02040
gene id: 465817:ETA_RS02040
uniprot id: B2VG60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

465817:ETA RS01680
gene id: 465817:ETA_RS01680
uniprot id: B2VGA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

465817:ETA RS07760
gene id: 465817:ETA_RS07760
uniprot id: B2VFQ1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

465817:ETA RS07375
gene id: 465817:ETA_RS07375
uniprot id: B2VII6
names: Similarity
messages: Belongs to the UPF0352 family.

465817:ETA RS12500
gene id: 465817:ETA_RS12500
uniprot id: B2VBV0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS15875
gene id: 465817:ETA_RS15875
uniprot id: B2VCY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

465817:ETA RS00785
gene id: 465817:ETA_RS00785
uniprot id: B2VBA2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

465817:ETA RS17620
gene id: 465817:ETA_RS17620
uniprot id: B2VJP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

465817:ETA RS03365
gene id: 465817:ETA_RS03365
uniprot id: B2VGG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

465817:ETA RS05515
gene id: 465817:ETA_RS05515
uniprot id: B2VE17
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

465817:ETA RS10485
gene id: 465817:ETA_RS10485
uniprot id: B2VEI2
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS12965
gene id: 465817:ETA_RS12965
uniprot id: B2VBK0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

465817:ETA RS13365
gene id: 465817:ETA_RS13365
uniprot id: B2VBD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

465817:ETA RS05950
gene id: 465817:ETA_RS05950
uniprot id: B2VEC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

465817:ETA RS16970
gene id: 465817:ETA_RS16970
uniprot id: B2VK53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

465817:ETA RS16025
gene id: 465817:ETA_RS16025
uniprot id: B2VCX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

465817:ETA RS12895
gene id: 465817:ETA_RS12895
uniprot id: B2VBM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS08460
gene id: 465817:ETA_RS08460
uniprot id: B2VJA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

465817:ETA RS13490
gene id: 465817:ETA_RS13490
uniprot id: B2VHW7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

465817:ETA RS02485
gene id: 465817:ETA_RS02485
uniprot id: B2VL75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

465817:ETA RS08145
gene id: 465817:ETA_RS08145
uniprot id: B2VFG0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

465817:ETA RS12100
gene id: 465817:ETA_RS12100
uniprot id: B2VC24
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS04900
gene id: 465817:ETA_RS04900
uniprot id: B2VD96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

465817:ETA RS15055
gene id: 465817:ETA_RS15055
uniprot id: B2VFS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
messages: In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.
messages: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.

465817:ETA RS05055
gene id: 465817:ETA_RS05055
uniprot id: B2VI07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

465817:ETA RS04775
gene id: 465817:ETA_RS04775
uniprot id: B2VD98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

465817:ETA RS04530
gene id: 465817:ETA_RS04530
uniprot id: B2VH36
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS03465
gene id: 465817:ETA_RS03465
uniprot id: B2VGE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS07140
gene id: 465817:ETA_RS07140
uniprot id: B2VIN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465817:ETA RS05930
gene id: 465817:ETA_RS05930
uniprot id: B2VEC2
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

465817:ETA RS13830
gene id: 465817:ETA_RS13830
uniprot id: B2VHT2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

465817:ETA RS15005
gene id: 465817:ETA_RS15005
uniprot id: B2VFU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

465817:ETA RS13765
gene id: 465817:ETA_RS13765
uniprot id: B2VHS5
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS09705
gene id: 465817:ETA_RS09705
uniprot id: B2VKH2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

465817:ETA RS05085
gene id: 465817:ETA_RS05085
uniprot id: B2VD53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

465817:ETA RS14995
gene id: 465817:ETA_RS14995
uniprot id: B2VFU4
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS11350
gene id: 465817:ETA_RS11350
uniprot id: B2VDJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

465817:ETA RS01915
gene id: 465817:ETA_RS01915
uniprot id: B2VG80
names: Similarity
messages: Belongs to the GARS family.

465817:ETA RS02680
gene id: 465817:ETA_RS02680
uniprot id: B2VGV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

465817:ETA RS12300
gene id: 465817:ETA_RS12300
uniprot id: B2VBY4
names: Similarity
messages: Belongs to the CFA/CMAS family.

465817:ETA RS15660
gene id: 465817:ETA_RS15660
uniprot id: B2VDD9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465817:ETA RS15715
gene id: 465817:ETA_RS15715
uniprot id: B2VDB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).

465817:ETA RS16555
gene id: 465817:ETA_RS16555
uniprot id: B2VKE6
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS10985
gene id: 465817:ETA_RS10985
uniprot id: B2VDR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

465817:ETA RS17095
gene id: 465817:ETA_RS17095
uniprot id: B2VK47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

465817:ETA RS02085
gene id: 465817:ETA_RS02085
uniprot id: B2VG48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Membrane
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

465817:ETA RS12605
gene id: 465817:ETA_RS12605
uniprot id: B2VBT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

465817:ETA RS13935
gene id: 465817:ETA_RS13935
uniprot id: B2VIS1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS12350
gene id: 465817:ETA_RS12350
uniprot id: B2VBV5
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS05080
gene id: 465817:ETA_RS05080
uniprot id: B2VD52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

465817:ETA RS08005
gene id: 465817:ETA_RS08005
uniprot id: B2VFI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS10215
gene id: 465817:ETA_RS10215
uniprot id: B2VJZ4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

465817:ETA RS09605
gene id: 465817:ETA_RS09605
uniprot id: B2VKI3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

465817:ETA RS17145
gene id: 465817:ETA_RS17145
uniprot id: B2VK23
names: Similarity
messages: Belongs to the phosphoribulokinase family.

465817:ETA RS07145
gene id: 465817:ETA_RS07145
uniprot id: B2VIN5
names: Subcellular Location Annotation
names: Subunit
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

465817:ETA RS14170
gene id: 465817:ETA_RS14170
uniprot id: B2VIQ7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

465817:ETA RS09120
gene id: 465817:ETA_RS09120
uniprot id: B2VKT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

465817:ETA RS11085
gene id: 465817:ETA_RS11085
uniprot id: B2VDP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

465817:ETA RS13170
gene id: 465817:ETA_RS13170
uniprot id: B2VBH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS05495
gene id: 465817:ETA_RS05495
uniprot id: B2VE29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

465817:ETA RS18540
gene id: 465817:ETA_RS18540
uniprot id: B2VCC8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS10320
gene id: 465817:ETA_RS10320
uniprot id: B2VEL8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

465817:ETA RS06315
gene id: 465817:ETA_RS06315
uniprot id: B2VE67
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

465817:ETA RS12310
gene id: 465817:ETA_RS12310
uniprot id: B2VBY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS15215
gene id: 465817:ETA_RS15215
uniprot id: B2VF38
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

465817:ETA RS08430
gene id: 465817:ETA_RS08430
uniprot id: B2VJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

465817:ETA RS13540
gene id: 465817:ETA_RS13540
uniprot id: B2VCL6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

465817:ETA RS02060
gene id: 465817:ETA_RS02060
uniprot id: B2VG64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

465817:ETA RS13705
gene id: 465817:ETA_RS13705
uniprot id: B2VHU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

465817:ETA RS14970
gene id: 465817:ETA_RS14970
uniprot id: B2VFW6
names: Similarity
messages: Belongs to the arginase family.

465817:ETA RS14935
gene id: 465817:ETA_RS14935
uniprot id: B2VFV9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

465817:ETA RS07565
gene id: 465817:ETA_RS07565
uniprot id: B2VIF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

465817:ETA RS05460
gene id: 465817:ETA_RS05460
uniprot id: B2VE22
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS03585
gene id: 465817:ETA_RS03585
uniprot id: B2VGD4
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS11735
gene id: 465817:ETA_RS11735
uniprot id: B2VC94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS04795
gene id: 465817:ETA_RS04795
uniprot id: B2VDA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

465817:ETA RS14445
gene id: 465817:ETA_RS14445
uniprot id: B2VHD8
names: Similarity
messages: Belongs to the CTP synthase family.

465817:ETA RS10935
gene id: 465817:ETA_RS10935
uniprot id: B2VDQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

465817:ETA RS02870
gene id: 465817:ETA_RS02870
uniprot id: B2VGN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

465817:ETA RS17605
gene id: 465817:ETA_RS17605
uniprot id: B2VJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

465817:ETA RS15775
gene id: 465817:ETA_RS15775
uniprot id: B2VDC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

465817:ETA RS08135
gene id: 465817:ETA_RS08135
uniprot id: B2VFF8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS04805
gene id: 465817:ETA_RS04805
uniprot id: B2VDA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS05480
gene id: 465817:ETA_RS05480
uniprot id: B2VE26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

465817:ETA RS12955
gene id: 465817:ETA_RS12955
uniprot id: B2VBJ8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

465817:ETA RS07430
gene id: 465817:ETA_RS07430
uniprot id: B2VIJ7
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS02220
gene id: 465817:ETA_RS02220
uniprot id: B2VI61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

465817:ETA RS09450
gene id: 465817:ETA_RS09450
uniprot id: B2VKL6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

465817:ETA RS01160
gene id: 465817:ETA_RS01160
uniprot id: B2VFA6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS13125
gene id: 465817:ETA_RS13125
uniprot id: B2VBG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS03545
gene id: 465817:ETA_RS03545
uniprot id: B2VKZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

465817:ETA RS16945
gene id: 465817:ETA_RS16945
uniprot id: B2VK80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

465817:ETA RS10250
gene id: 465817:ETA_RS10250
uniprot id: B2VK01
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

465817:ETA RS18170
gene id: 465817:ETA_RS18170
uniprot id: B2VCI7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS13505
gene id: 465817:ETA_RS13505
uniprot id: B2VHX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS09035
gene id: 465817:ETA_RS09035
uniprot id: B2VKU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

465817:ETA RS05980
gene id: 465817:ETA_RS05980
uniprot id: B2VI38
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465817:ETA RS06195
gene id: 465817:ETA_RS06195
uniprot id: B2VE88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RodZ family.
messages: Cell inner membrane
messages: Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
messages: The helix-turn-helix (HTH) motif in the cytoplasmic domain of the N-terminus is involved in the formation of spirals to maintain the rigid rod shape. As this protein is anchored in the cytoplasmic membrane, the HTH motif may contribute to protein-protein interactions to form the RodZ helix, which is localized beneath the cytoplasmic membrane. The C-terminal domain may be critical for determination of the rod shape by probably interacting with enzymes required for synthesis of the peptidoglycan layer, including PBPs in the periplasm.

465817:ETA RS12395
gene id: 465817:ETA_RS12395
uniprot id: B2VBW4
names: Similarity
messages: Belongs to the MoaD family.

465817:ETA RS02100
gene id: 465817:ETA_RS02100
uniprot id: B2VG52
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

465817:ETA RS10400
gene id: 465817:ETA_RS10400
uniprot id: B2VEK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

465817:ETA RS01065
gene id: 465817:ETA_RS01065
uniprot id: B2VFB4
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS08560
gene id: 465817:ETA_RS08560
uniprot id: B2VJ91
names: Cofactor
names: Similarity
messages: Belongs to the Nudix hydrolase family.
messages: Binds 1 Mg(2+) ion per subunit.

465817:ETA RS01580
gene id: 465817:ETA_RS01580
uniprot id: B2VI86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsN family.
messages: Cell inner membrane
messages: Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
messages: Interacts with FtsA via its N-terminal cytoplasmic domain.

465817:ETA RS18445
gene id: 465817:ETA_RS18445
uniprot id: B2VCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

465817:ETA RS11875
gene id: 465817:ETA_RS11875
uniprot id: B2VC56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

465817:ETA RS08625
gene id: 465817:ETA_RS08625
uniprot id: B2VJA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

465817:ETA RS11665
gene id: 465817:ETA_RS11665
uniprot id: B2VDF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

465817:ETA RS16960
gene id: 465817:ETA_RS16960
uniprot id: B2VK51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

465817:ETA RS13250
gene id: 465817:ETA_RS13250
uniprot id: B2VBE7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS15235
gene id: 465817:ETA_RS15235
uniprot id: B2VF42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

465817:ETA RS13650
gene id: 465817:ETA_RS13650
uniprot id: B2VIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

465817:ETA RS08485
gene id: 465817:ETA_RS08485
uniprot id: B2VJB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

465817:ETA RS12650
gene id: 465817:ETA_RS12650
uniprot id: B2VBR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

465817:ETA RS06635
gene id: 465817:ETA_RS06635
uniprot id: B2VE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

465817:ETA RS14765
gene id: 465817:ETA_RS14765
uniprot id: B2VFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS03770
gene id: 465817:ETA_RS03770
uniprot id: B2VGC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. T3SS SctC subfamily.
messages: Cell outer membrane
messages: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
messages: Membrane
messages: The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.

465817:ETA RS01440
gene id: 465817:ETA_RS01440
uniprot id: B2VL53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

465817:ETA RS06960
gene id: 465817:ETA_RS06960
uniprot id: B2VIW3
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS01785
gene id: 465817:ETA_RS01785
uniprot id: B2VG93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

465817:ETA RS09515
gene id: 465817:ETA_RS09515
uniprot id: B2VKJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

465817:ETA RS17455
gene id: 465817:ETA_RS17455
uniprot id: B2VJS1
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

465817:ETA RS05350
gene id: 465817:ETA_RS05350
uniprot id: B2VD16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS11515
gene id: 465817:ETA_RS11515
uniprot id: B2VIA6
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS10835
gene id: 465817:ETA_RS10835
uniprot id: B2VDT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

465817:ETA RS06420
gene id: 465817:ETA_RS06420
uniprot id: B2VE51
names: Similarity
messages: Belongs to the ArsC family.

465817:ETA RS02860
gene id: 465817:ETA_RS02860
uniprot id: B2VGS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

465817:ETA RS13980
gene id: 465817:ETA_RS13980
uniprot id: B2VIT2
names: Similarity
messages: Belongs to the UPF0178 family.

465817:ETA RS11370
gene id: 465817:ETA_RS11370
uniprot id: B2VDJ1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS11625
gene id: 465817:ETA_RS11625
uniprot id: B2VDE3
names: Caution
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS07920
gene id: 465817:ETA_RS07920
uniprot id: B2VFK0
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

465817:ETA RS11900
gene id: 465817:ETA_RS11900
uniprot id: B2VC61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

465817:ETA RS13670
gene id: 465817:ETA_RS13670
uniprot id: B2VIU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

465817:ETA RS04830
gene id: 465817:ETA_RS04830
uniprot id: B2VDB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

465817:ETA RS09845
gene id: 465817:ETA_RS09845
uniprot id: B2VET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

465817:ETA RS10430
gene id: 465817:ETA_RS10430
uniprot id: B2VJY3
names: Similarity
messages: Belongs to the intimin/invasin family.

465817:ETA RS12405
gene id: 465817:ETA_RS12405
uniprot id: B2VBW6
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

465817:ETA RS06435
gene id: 465817:ETA_RS06435
uniprot id: B2VE54
names: Function
names: Similarity
messages: Belongs to the channel forming colicin family.
messages: Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.
messages: This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.

465817:ETA RS07180
gene id: 465817:ETA_RS07180
uniprot id: B2VIP2
names: Similarity
messages: Belongs to the CinA family.

465817:ETA RS07820
gene id: 465817:ETA_RS07820
uniprot id: B2VFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

465817:ETA RS07035
gene id: 465817:ETA_RS07035
uniprot id: B2VIX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

465817:ETA RS03300
gene id: 465817:ETA_RS03300
uniprot id: B2VGH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

465817:ETA RS11565
gene id: 465817:ETA_RS11565
uniprot id: B2VDG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

465817:ETA RS14020
gene id: 465817:ETA_RS14020
uniprot id: B2VHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

465817:ETA RS02160
gene id: 465817:ETA_RS02160
uniprot id: B2VI49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS12325
gene id: 465817:ETA_RS12325
uniprot id: B2VBZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

465817:ETA RS15850
gene id: 465817:ETA_RS15850
uniprot id: B2VD04
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Probable metalloprotease.

465817:ETA RS05755
gene id: 465817:ETA_RS05755
uniprot id: B2VDX1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS16725
gene id: 465817:ETA_RS16725
uniprot id: B2VKA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

465817:ETA RS14345
gene id: 465817:ETA_RS14345
uniprot id: B2VHJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

465817:ETA RS06610
gene id: 465817:ETA_RS06610
uniprot id: B2VDY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

465817:ETA RS05010
gene id: 465817:ETA_RS05010
uniprot id: B2VHZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

465817:ETA RS09125
gene id: 465817:ETA_RS09125
uniprot id: B2VKT3
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

465817:ETA RS12245
gene id: 465817:ETA_RS12245
uniprot id: B2VBX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

465817:ETA RS01225
gene id: 465817:ETA_RS01225
uniprot id: B2VF86
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS06340
gene id: 465817:ETA_RS06340
uniprot id: B2VE71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

465817:ETA RS07420
gene id: 465817:ETA_RS07420
uniprot id: B2VIJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS05035
gene id: 465817:ETA_RS05035
uniprot id: B2VI03
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

465817:ETA RS02420
gene id: 465817:ETA_RS02420
uniprot id: B2VGZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS01875
gene id: 465817:ETA_RS01875
uniprot id: B2VG74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

465817:ETA RS16095
gene id: 465817:ETA_RS16095
uniprot id: B2VL80
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

465817:ETA RS01995
gene id: 465817:ETA_RS01995
uniprot id: B2VI72
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

465817:ETA RS16880
gene id: 465817:ETA_RS16880
uniprot id: B2VK97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

465817:ETA RS15275
gene id: 465817:ETA_RS15275
uniprot id: B2VF22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

465817:ETA RS09075
gene id: 465817:ETA_RS09075
uniprot id: B2VKV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane

465817:ETA RS04415
gene id: 465817:ETA_RS04415
uniprot id: B2VH43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

465817:ETA RS11150
gene id: 465817:ETA_RS11150
uniprot id: B2VDM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LpoB family.
messages: Cell outer membrane
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

465817:ETA RS10080
gene id: 465817:ETA_RS10080
uniprot id: B2VEN9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465817:ETA RS15105
gene id: 465817:ETA_RS15105
uniprot id: B2VFT8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS09060
gene id: 465817:ETA_RS09060
uniprot id: B2VKV1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS16020
gene id: 465817:ETA_RS16020
uniprot id: B2VCX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

465817:ETA RS11100
gene id: 465817:ETA_RS11100
uniprot id: B2VDM4
names: Function
names: Similarity
messages: Belongs to the RcsA family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes.

465817:ETA RS17420
gene id: 465817:ETA_RS17420
uniprot id: B2VJU6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

465817:ETA RS15400
gene id: 465817:ETA_RS15400
uniprot id: B2VEZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

465817:ETA RS04820
gene id: 465817:ETA_RS04820
uniprot id: B2VDA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

465817:ETA RS09355
gene id: 465817:ETA_RS09355
uniprot id: B2VKN0
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

465817:ETA RS16580
gene id: 465817:ETA_RS16580
uniprot id: B2VKF1
names: Similarity
messages: Belongs to the GST superfamily.

465817:ETA RS09375
gene id: 465817:ETA_RS09375
uniprot id: B2VKN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

465817:ETA RS03530
gene id: 465817:ETA_RS03530
uniprot id: B2VKZ5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

465817:ETA RS13100
gene id: 465817:ETA_RS13100
uniprot id: B2VBJ3
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

465817:ETA RS13800
gene id: 465817:ETA_RS13800
uniprot id: B2VHS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

465817:ETA RS08280
gene id: 465817:ETA_RS08280
uniprot id: B2VFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

465817:ETA RS10405
gene id: 465817:ETA_RS10405
uniprot id: B2VJX8
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

465817:ETA RS11760
gene id: 465817:ETA_RS11760
uniprot id: B2VC99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

465817:ETA RS11065
gene id: 465817:ETA_RS11065
uniprot id: B2VDP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

465817:ETA RS15265
gene id: 465817:ETA_RS15265
uniprot id: B2VF20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell inner membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

465817:ETA RS03575
gene id: 465817:ETA_RS03575
uniprot id: B2VGD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

465817:ETA RS06240
gene id: 465817:ETA_RS06240
uniprot id: B2VEA0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

465817:ETA RS04470
gene id: 465817:ETA_RS04470
uniprot id: B2VH22
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

465817:ETA RS17815
gene id: 465817:ETA_RS17815
uniprot id: B2VHF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family. RNase BN subfamily.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.

465817:ETA RS04855
gene id: 465817:ETA_RS04855
uniprot id: B2VD86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

465817:ETA RS02635
gene id: 465817:ETA_RS02635
uniprot id: B2VGU9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

465817:ETA RS06225
gene id: 465817:ETA_RS06225
uniprot id: B2VE94
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

465817:ETA RS08285
gene id: 465817:ETA_RS08285
uniprot id: B2VFF5
names: Function
names: Similarity
messages: Belongs to the EfeM/EfeO family.
messages: Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component.

465817:ETA RS16135
gene id: 465817:ETA_RS16135
uniprot id: B2VL88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

465817:ETA RS01560
gene id: 465817:ETA_RS01560
uniprot id: B2VES1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

465817:ETA RS02045
gene id: 465817:ETA_RS02045
uniprot id: B2VG61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

465817:ETA RS03595
gene id: 465817:ETA_RS03595
uniprot id: B2VGC5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

465817:ETA RS08275
gene id: 465817:ETA_RS08275
uniprot id: B2VFF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS15295
gene id: 465817:ETA_RS15295
uniprot id: B2VF26
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

465817:ETA RS00305
gene id: 465817:ETA_RS00305
uniprot id: B2VAV4
names: Function
names: Similarity
messages: Belongs to the GSP E family.
messages: Part of the Type IV secretion system.

465817:ETA RS04725
gene id: 465817:ETA_RS04725
uniprot id: B2VGP9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

465817:ETA RS01435
gene id: 465817:ETA_RS01435
uniprot id: B2VL52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

465817:ETA RS01470
gene id: 465817:ETA_RS01470
uniprot id: B2VF60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

465817:ETA RS16575
gene id: 465817:ETA_RS16575
uniprot id: B2VKF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

465817:ETA RS01770
gene id: 465817:ETA_RS01770
uniprot id: B2VG90
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS08230
gene id: 465817:ETA_RS08230
uniprot id: B2VES7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

465817:ETA RS04375
gene id: 465817:ETA_RS04375
uniprot id: B2VH37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS07865
gene id: 465817:ETA_RS07865
uniprot id: B2VFL7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

465817:ETA RS02760
gene id: 465817:ETA_RS02760
uniprot id: B2VGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

465817:ETA RS06980
gene id: 465817:ETA_RS06980
uniprot id: B2VIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

465817:ETA RS14530
gene id: 465817:ETA_RS14530
uniprot id: B2VHD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

465817:ETA RS15220
gene id: 465817:ETA_RS15220
uniprot id: B2VF39
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

465817:ETA RS12945
gene id: 465817:ETA_RS12945
uniprot id: B2VBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

465817:ETA RS17830
gene id: 465817:ETA_RS17830
uniprot id: B2VHF4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465817:ETA RS04860
gene id: 465817:ETA_RS04860
uniprot id: B2VD87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

465817:ETA RS11720
gene id: 465817:ETA_RS11720
uniprot id: B2VC91
names: Similarity
messages: Belongs to the peptidase M1 family.

465817:ETA RS07225
gene id: 465817:ETA_RS07225
uniprot id: B2VIM1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

465817:ETA RS12980
gene id: 465817:ETA_RS12980
uniprot id: B2VBK3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

465817:ETA RS08950
gene id: 465817:ETA_RS08950
uniprot id: B2VKW3
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

465817:ETA RS02030
gene id: 465817:ETA_RS02030
uniprot id: B2VG58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

465817:ETA RS10030
gene id: 465817:ETA_RS10030
uniprot id: B2VER2
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

465817:ETA RS10295
gene id: 465817:ETA_RS10295
uniprot id: B2VEK9
names: Function
names: Similarity
messages: Belongs to the glutathione peroxidase family. BtuE subfamily.
messages: Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.

465817:ETA RS02075
gene id: 465817:ETA_RS02075
uniprot id: B2VG67
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS01205
gene id: 465817:ETA_RS01205
uniprot id: B2VL60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

465817:ETA RS06120
gene id: 465817:ETA_RS06120
uniprot id: B2VI25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS05620
gene id: 465817:ETA_RS05620
uniprot id: B2VHY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

465817:ETA RS16995
gene id: 465817:ETA_RS16995
uniprot id: B2VK58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

465817:ETA RS06135
gene id: 465817:ETA_RS06135
uniprot id: B2VI28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

465817:ETA RS04490
gene id: 465817:ETA_RS04490
uniprot id: B2VH28
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

465817:ETA RS14490
gene id: 465817:ETA_RS14490
uniprot id: B2VHC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

465817:ETA RS02310
gene id: 465817:ETA_RS02310
uniprot id: B2VFE1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

465817:ETA RS06415
gene id: 465817:ETA_RS06415
uniprot id: B2VE50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

465817:ETA RS01100
gene id: 465817:ETA_RS01100
uniprot id: B2VFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS17000
gene id: 465817:ETA_RS17000
uniprot id: B2VK59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

465817:ETA RS06715
gene id: 465817:ETA_RS06715
uniprot id: B2VDX5
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

465817:ETA RS17300
gene id: 465817:ETA_RS17300
uniprot id: B2VJV3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

465817:ETA RS17425
gene id: 465817:ETA_RS17425
uniprot id: B2VJU7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

465817:ETA RS04655
gene id: 465817:ETA_RS04655
uniprot id: B2VGR4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

465817:ETA RS01595
gene id: 465817:ETA_RS01595
uniprot id: B2VI89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

465817:ETA RS05095
gene id: 465817:ETA_RS05095
uniprot id: B2VD55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

465817:ETA RS10255
gene id: 465817:ETA_RS10255
uniprot id: B2VK02
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

465817:ETA RS13060
gene id: 465817:ETA_RS13060
uniprot id: B2VBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

465817:ETA RS04500
gene id: 465817:ETA_RS04500
uniprot id: B2VH30
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

465817:ETA RS14195
gene id: 465817:ETA_RS14195
uniprot id: B2VIR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

465817:ETA RS07165
gene id: 465817:ETA_RS07165
uniprot id: B2VIN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

465817:ETA RS10740
gene id: 465817:ETA_RS10740
uniprot id: B2VIE5
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

465817:ETA RS11960
gene id: 465817:ETA_RS11960
uniprot id: B2VC37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

465817:ETA RS12105
gene id: 465817:ETA_RS12105
uniprot id: B2VC25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

465817:ETA RS01170
gene id: 465817:ETA_RS01170
uniprot id: B2VFA8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

465817:ETA RS05985
gene id: 465817:ETA_RS05985
uniprot id: B2VI39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

465817:ETA RS01120
gene id: 465817:ETA_RS01120
uniprot id: B2VFA0
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

465817:ETA RS11275
gene id: 465817:ETA_RS11275
uniprot id: B2VIB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

465817:ETA RS10345
gene id: 465817:ETA_RS10345
uniprot id: B2VEJ8
names: Similarity
messages: Belongs to the fructosamine kinase family.

465817:ETA RS09010
gene id: 465817:ETA_RS09010
uniprot id: B2VKX4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

465817:ETA RS17350
gene id: 465817:ETA_RS17350
uniprot id: B2VJT1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

465817:ETA RS12645
gene id: 465817:ETA_RS12645
uniprot id: B2VBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS01000
gene id: 465817:ETA_RS01000
uniprot id: B2VFD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

465817:ETA RS13620
gene id: 465817:ETA_RS13620
uniprot id: B2VHW4
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

465817:ETA RS11825
gene id: 465817:ETA_RS11825
uniprot id: B2VC78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

465817:ETA RS12610
gene id: 465817:ETA_RS12610
uniprot id: B2VBT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

465817:ETA RS18595
gene id: 465817:ETA_RS18595
uniprot id: B2VCB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

465817:ETA RS16835
gene id: 465817:ETA_RS16835
uniprot id: B2VK88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

465817:ETA RS16005
gene id: 465817:ETA_RS16005
uniprot id: B2VCX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.
messages: Membrane

465817:ETA RS03705
gene id: 465817:ETA_RS03705
uniprot id: B2VKY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS12780
gene id: 465817:ETA_RS12780
uniprot id: B2VBN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

465817:ETA RS10155
gene id: 465817:ETA_RS10155
uniprot id: B2VEM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS08235
gene id: 465817:ETA_RS08235
uniprot id: B2VES8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

465817:ETA RS14610
gene id: 465817:ETA_RS14610
uniprot id: B2VG11
names: Similarity
messages: Belongs to the LcrH/SycD chaperone family.

465817:ETA RS02135
gene id: 465817:ETA_RS02135
uniprot id: B2VG50
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

465817:ETA RS11285
gene id: 465817:ETA_RS11285
uniprot id: B2VIB4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

465817:ETA RS15000
gene id: 465817:ETA_RS15000
uniprot id: B2VFU5
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS06330
gene id: 465817:ETA_RS06330
uniprot id: B2VE64
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS02715
gene id: 465817:ETA_RS02715
uniprot id: B2VL65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

465817:ETA RS09385
gene id: 465817:ETA_RS09385
uniprot id: B2VKN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane
messages: Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.

465817:ETA RS05665
gene id: 465817:ETA_RS05665
uniprot id: B2VDZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

465817:ETA RS16090
gene id: 465817:ETA_RS16090
uniprot id: B2VCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

465817:ETA RS15430
gene id: 465817:ETA_RS15430
uniprot id: B2VEZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

465817:ETA RS18115
gene id: 465817:ETA_RS18115
uniprot id: B2VCL1
names: Similarity
messages: Belongs to the peptidase M16 family.

465817:ETA RS13560
gene id: 465817:ETA_RS13560
uniprot id: B2VHV0
names: Subcellular Location Annotation
messages: Cell inner membrane

465817:ETA RS03400
gene id: 465817:ETA_RS03400
uniprot id: B2VGG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane

465817:ETA RS15630
gene id: 465817:ETA_RS15630
uniprot id: B2VL11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

465817:ETA RS17030
gene id: 465817:ETA_RS17030
uniprot id: B2VK34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

465817:ETA RS17285
gene id: 465817:ETA_RS17285
uniprot id: B2VJU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

465817:ETA RS12120
gene id: 465817:ETA_RS12120
uniprot id: B2VC28
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS11915
gene id: 465817:ETA_RS11915
uniprot id: B2VC64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

465817:ETA RS06895
gene id: 465817:ETA_RS06895
uniprot id: B2VIY9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

465817:ETA RS05610
gene id: 465817:ETA_RS05610
uniprot id: B2VHY3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

465817:ETA RS17635
gene id: 465817:ETA_RS17635
uniprot id: B2VJP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

465817:ETA RS07175
gene id: 465817:ETA_RS07175
uniprot id: B2VIP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

465817:ETA RS04840
gene id: 465817:ETA_RS04840
uniprot id: B2VD84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

465817:ETA RS12630
gene id: 465817:ETA_RS12630
uniprot id: B2VBR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

465817:ETA RS00325
gene id: 465817:ETA_RS00325
uniprot id: B2VAV8
names: Similarity
messages: Belongs to the bacterial secretin family.

465817:ETA RS15435
gene id: 465817:ETA_RS15435
uniprot id: B2VEZ8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

465817:ETA RS19300
gene id: 465817:ETA_RS19300
uniprot id: B2VDK9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

465817:ETA RS02890
gene id: 465817:ETA_RS02890
uniprot id: B2VGN8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

465817:ETA RS12615
gene id: 465817:ETA_RS12615
uniprot id: B2VBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

465817:ETA RS05655
gene id: 465817:ETA_RS05655
uniprot id: B2VE00
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

465817:ETA RS02245
gene id: 465817:ETA_RS02245
uniprot id: B2VFE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

465817:ETA RS12010
gene id: 465817:ETA_RS12010
uniprot id: B2VC47
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

465817:ETA RS02725
gene id: 465817:ETA_RS02725
uniprot id: B2VL67
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS09070
gene id: 465817:ETA_RS09070
uniprot id: B2VKV3
names: Similarity
messages: Belongs to the UPF0263 family.

465817:ETA RS01660
gene id: 465817:ETA_RS01660
uniprot id: B2VGA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

465817:ETA RS01545
gene id: 465817:ETA_RS01545
uniprot id: B2VER8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

465817:ETA RS02695
gene id: 465817:ETA_RS02695
uniprot id: B2VGV6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

465817:ETA RS07440
gene id: 465817:ETA_RS07440
uniprot id: B2VIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxT phosphotransferase family.
messages: Cell inner membrane
messages: Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P).

465817:ETA RS07255
gene id: 465817:ETA_RS07255
uniprot id: B2VIM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

465817:ETA RS01280
gene id: 465817:ETA_RS01280
uniprot id: B2VF92
names: Similarity
messages: Belongs to the YicC/YloC family.

465817:ETA RS04665
gene id: 465817:ETA_RS04665
uniprot id: B2VGR6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

465817:ETA RS10555
gene id: 465817:ETA_RS10555
uniprot id: B2VEG2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

465817:ETA RS08780
gene id: 465817:ETA_RS08780
uniprot id: B2VJ71
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

465817:ETA RS06185
gene id: 465817:ETA_RS06185
uniprot id: B2VE98
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

465817:ETA RS08735
gene id: 465817:ETA_RS08735
uniprot id: B2VJ62
names: Subcellular Location Annotation
messages: Cytoplasm

465817:ETA RS09080
gene id: 465817:ETA_RS09080
uniprot id: B2VKV6
names: Similarity
messages: Belongs to the YciI family.

465817:ETA RS03205
gene id: 465817:ETA_RS03205
uniprot id: B2VGI9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

465817:ETA RS03235
gene id: 465817:ETA_RS03235
uniprot id: B2VGJ4
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

465817:ETA RS08180
gene id: 465817:ETA_RS08180
uniprot id: B2VFG5
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

465817:ETA RS10800
gene id: 465817:ETA_RS10800
uniprot id: B2VDU4
names: Similarity
messages: Belongs to the peptidase S66 family.

465817:ETA RS12520
gene id: 465817:ETA_RS12520
uniprot id: B2VBS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

465817:ETA RS03260
gene id: 465817:ETA_RS03260
uniprot id: B2VGK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

465817:ETA RS01865
gene id: 465817:ETA_RS01865
uniprot id: B2VG85
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

465817:ETA RS17780
gene id: 465817:ETA_RS17780
uniprot id: B2VHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane

465817:ETA RS04080
gene id: 465817:ETA_RS04080
uniprot id: B2VH87
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS13455
gene id: 465817:ETA_RS13455
uniprot id: B2VBB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

465817:ETA RS09970
gene id: 465817:ETA_RS09970
uniprot id: B2VEQ9
names: Similarity
messages: Belongs to the ribulokinase family.

465817:ETA RS07625
gene id: 465817:ETA_RS07625
uniprot id: B2VIG5
names: Subcellular Location Annotation
messages: Cell inner membrane

465817:ETA RS10275
gene id: 465817:ETA_RS10275
uniprot id: B2VEL1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS00355
gene id: 465817:ETA_RS00355
uniprot id: B2VAY0
names: Similarity
messages: Belongs to the GSP E family.

465817:ETA RS15560
gene id: 465817:ETA_RS15560
uniprot id: B2VEX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

465817:ETA RS06150
gene id: 465817:ETA_RS06150
uniprot id: B2VI30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS18255
gene id: 465817:ETA_RS18255
uniprot id: B2VCH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

465817:ETA RS18510
gene id: 465817:ETA_RS18510
uniprot id: B2VCC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

465817:ETA RS09485
gene id: 465817:ETA_RS09485
uniprot id: B2VKM3
names: Similarity
messages: Belongs to the peptidase S1B family.

465817:ETA RS09020
gene id: 465817:ETA_RS09020
uniprot id: B2VKX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

465817:ETA RS04650
gene id: 465817:ETA_RS04650
uniprot id: B2VH05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

465817:ETA RS12380
gene id: 465817:ETA_RS12380
uniprot id: B2VBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

465817:ETA RS10930
gene id: 465817:ETA_RS10930
uniprot id: B2VID3
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

465817:ETA RS08715
gene id: 465817:ETA_RS08715
uniprot id: B2VJ57
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

465817:ETA RS04835
gene id: 465817:ETA_RS04835
uniprot id: B2VD83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

465817:ETA RS12060
gene id: 465817:ETA_RS12060
uniprot id: B2VC17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

465817:ETA RS02510
gene id: 465817:ETA_RS02510
uniprot id: B2VGX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

465817:ETA RS16545
gene id: 465817:ETA_RS16545
uniprot id: B2VKE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Transports acetate.

465817:ETA RS02010
gene id: 465817:ETA_RS02010
uniprot id: B2VG69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

465817:ETA RS17210
gene id: 465817:ETA_RS17210
uniprot id: B2VJW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

465817:ETA RS06785
gene id: 465817:ETA_RS06785
uniprot id: B2VJ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

465817:ETA RS05505
gene id: 465817:ETA_RS05505
uniprot id: B2VE08
names: Similarity
messages: Belongs to the UPF0325 family.

465817:ETA RS17640
gene id: 465817:ETA_RS17640
uniprot id: B2VJP5
names: Similarity
messages: Belongs to the TPP enzyme family.

465817:ETA RS13785
gene id: 465817:ETA_RS13785
uniprot id: B2VHS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

465817:ETA RS15360
gene id: 465817:ETA_RS15360
uniprot id: B2VF11
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

465817:ETA RS13825
gene id: 465817:ETA_RS13825
uniprot id: B2VHT1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

465817:ETA RS17290
gene id: 465817:ETA_RS17290
uniprot id: B2VJV0
names: Subcellular Location Annotation
messages: Cell inner membrane

465817:ETA RS02620
gene id: 465817:ETA_RS02620
uniprot id: B2VGX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS14755
gene id: 465817:ETA_RS14755
uniprot id: B2VG08
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

465817:ETA RS14795
gene id: 465817:ETA_RS14795
uniprot id: B2VFY8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

465817:ETA RS12160
gene id: 465817:ETA_RS12160
uniprot id: B2VBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS02950
gene id: 465817:ETA_RS02950
uniprot id: B2VL36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

465817:ETA RS06845
gene id: 465817:ETA_RS06845
uniprot id: B2VIX9
names: Similarity
messages: Belongs to the UPF0115 family.

465817:ETA RS14145
gene id: 465817:ETA_RS14145
uniprot id: B2VHN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell inner membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

465817:ETA RS06970
gene id: 465817:ETA_RS06970
uniprot id: B2VIW5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS15870
gene id: 465817:ETA_RS15870
uniprot id: B2VCY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

465817:ETA RS14495
gene id: 465817:ETA_RS14495
uniprot id: B2VHD0
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

465817:ETA RS12555
gene id: 465817:ETA_RS12555
uniprot id: B2VBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

465817:ETA RS14190
gene id: 465817:ETA_RS14190
uniprot id: B2VIR1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

465817:ETA RS00285
gene id: 465817:ETA_RS00285
uniprot id: B2VAV0
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS05365
gene id: 465817:ETA_RS05365
uniprot id: B2VD19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

465817:ETA RS04870
gene id: 465817:ETA_RS04870
uniprot id: B2VD90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

465817:ETA RS04925
gene id: 465817:ETA_RS04925
uniprot id: B2VD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

465817:ETA RS12435
gene id: 465817:ETA_RS12435
uniprot id: B2VBX2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

465817:ETA RS06855
gene id: 465817:ETA_RS06855
uniprot id: B2VIY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

465817:ETA RS08375
gene id: 465817:ETA_RS08375
uniprot id: B2VJC4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

465817:ETA RS01310
gene id: 465817:ETA_RS01310
uniprot id: B2VF80
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

465817:ETA RS17580
gene id: 465817:ETA_RS17580
uniprot id: B2VJN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

465817:ETA RS14225
gene id: 465817:ETA_RS14225
uniprot id: B2VHK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

465817:ETA RS01030
gene id: 465817:ETA_RS01030
uniprot id: B2VFD6
names: Similarity
messages: Belongs to the TPP enzyme family.

465817:ETA RS08725
gene id: 465817:ETA_RS08725
uniprot id: B2VJ59
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

465817:ETA RS11970
gene id: 465817:ETA_RS11970
uniprot id: B2VC39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS02780
gene id: 465817:ETA_RS02780
uniprot id: B2VGT1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

465817:ETA RS10955
gene id: 465817:ETA_RS10955
uniprot id: B2VDQ4
names: Subcellular Location Annotation
messages: Cell inner membrane

465817:ETA RS00310
gene id: 465817:ETA_RS00310
uniprot id: B2VAV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

465817:ETA RS13375
gene id: 465817:ETA_RS13375
uniprot id: B2VBD4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

465817:ETA RS07105
gene id: 465817:ETA_RS07105
uniprot id: B2VIV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465817:ETA RS08945
gene id: 465817:ETA_RS08945
uniprot id: B2VKW2
names: Similarity
messages: Belongs to the peptidase S49 family.

465817:ETA RS14740
gene id: 465817:ETA_RS14740
uniprot id: B2VG05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm

465817:ETA RS13585
gene id: 465817:ETA_RS13585
uniprot id: B2VHV7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

465817:ETA RS16565
gene id: 465817:ETA_RS16565
uniprot id: B2VKE8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS06015
gene id: 465817:ETA_RS06015
uniprot id: B2VI45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

465817:ETA RS08565
gene id: 465817:ETA_RS08565
uniprot id: B2VJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

465817:ETA RS14865
gene id: 465817:ETA_RS14865
uniprot id: B2VFX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS08570
gene id: 465817:ETA_RS08570
uniprot id: B2VJ93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

465817:ETA RS14605
gene id: 465817:ETA_RS14605
uniprot id: B2VG10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctE/SipB/YopB family.
messages: Host membrane

465817:ETA RS01510
gene id: 465817:ETA_RS01510
uniprot id: B2VF52
names: Similarity
messages: Belongs to the MQO family.

465817:ETA RS09585
gene id: 465817:ETA_RS09585
uniprot id: B2VKL0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

465817:ETA RS17435
gene id: 465817:ETA_RS17435
uniprot id: B2VJR7
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.

465817:ETA RS12125
gene id: 465817:ETA_RS12125
uniprot id: B2VC29
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465817:ETA RS17275
gene id: 465817:ETA_RS17275
uniprot id: B2VJX7
names: Similarity
messages: Belongs to the HSP15 family.

465817:ETA RS14615
gene id: 465817:ETA_RS14615
uniprot id: B2VG12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

465817:ETA RS16625
gene id: 465817:ETA_RS16625
uniprot id: B2VKC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

465817:ETA RS01215
gene id: 465817:ETA_RS01215
uniprot id: B2VL62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

465817:ETA RS02810
gene id: 465817:ETA_RS02810
uniprot id: B2VGS5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

465817:ETA RS10525
gene id: 465817:ETA_RS10525
uniprot id: B2VEI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

465817:ETA RS11920
gene id: 465817:ETA_RS11920
uniprot id: B2VC65
names: Similarity
messages: Belongs to the ClpA/ClpB family.

465817:ETA RS14745
gene id: 465817:ETA_RS14745
uniprot id: B2VG06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

465817:ETA RS16700
gene id: 465817:ETA_RS16700
uniprot id: B2VKA0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

465817:ETA RS02275
gene id: 465817:ETA_RS02275
uniprot id: B2VG43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

465817:ETA RS12115
gene id: 465817:ETA_RS12115
uniprot id: B2VC27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS01880
gene id: 465817:ETA_RS01880
uniprot id: B2VG75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

465817:ETA RS07690
gene id: 465817:ETA_RS07690
uniprot id: B2VFR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

465817:ETA RS16620
gene id: 465817:ETA_RS16620
uniprot id: B2VKC4
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

465817:ETA RS02095
gene id: 465817:ETA_RS02095
uniprot id: B2VG51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

465817:ETA RS16650
gene id: 465817:ETA_RS16650
uniprot id: B2VKC9
names: Similarity
messages: Belongs to the UPF0047 family.

465817:ETA RS03525
gene id: 465817:ETA_RS03525
uniprot id: B2VKZ4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

465817:ETA RS03335
gene id: 465817:ETA_RS03335
uniprot id: B2VGI5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

465817:ETA RS06665
gene id: 465817:ETA_RS06665
uniprot id: B2VE32
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS14770
gene id: 465817:ETA_RS14770
uniprot id: B2VFY3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

465817:ETA RS12925
gene id: 465817:ETA_RS12925
uniprot id: B2VBM7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

465817:ETA RS11415
gene id: 465817:ETA_RS11415
uniprot id: B2VDI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family. OpgC subfamily.
messages: Cell membrane
messages: Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.

465817:ETA RS16390
gene id: 465817:ETA_RS16390
uniprot id: B2VCP1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS04815
gene id: 465817:ETA_RS04815
uniprot id: B2VDA8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

465817:ETA RS12655
gene id: 465817:ETA_RS12655
uniprot id: B2VBR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

465817:ETA RS12360
gene id: 465817:ETA_RS12360
uniprot id: B2VBV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

465817:ETA RS18440
gene id: 465817:ETA_RS18440
uniprot id: B2VCE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

465817:ETA RS04570
gene id: 465817:ETA_RS04570
uniprot id: B2VH13
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.

465817:ETA RS03675
gene id: 465817:ETA_RS03675
uniprot id: B2VKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

465817:ETA RS06520
gene id: 465817:ETA_RS06520
uniprot id: B2VE36
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

465817:ETA RS02315
gene id: 465817:ETA_RS02315
uniprot id: B2VFE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

465817:ETA RS13065
gene id: 465817:ETA_RS13065
uniprot id: B2VBI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

465817:ETA RS11295
gene id: 465817:ETA_RS11295
uniprot id: B2VIB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

465817:ETA RS13755
gene id: 465817:ETA_RS13755
uniprot id: B2VHR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

465817:ETA RS06995
gene id: 465817:ETA_RS06995
uniprot id: B2VIX0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

465817:ETA RS16345
gene id: 465817:ETA_RS16345
uniprot id: B2VCQ9
names: Similarity
messages: Belongs to the IucA/IucC family.

465817:ETA RS13180
gene id: 465817:ETA_RS13180
uniprot id: B2VBH3
names: Subunit
messages: Monomer.

465817:ETA RS03380
gene id: 465817:ETA_RS03380
uniprot id: B2VGH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

465817:ETA RS09285
gene id: 465817:ETA_RS09285
uniprot id: B2VKP9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS19315
gene id: 465817:ETA_RS19315
uniprot id: B2VBY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0387 family.
messages: Cell inner membrane

465817:ETA RS13945
gene id: 465817:ETA_RS13945
uniprot id: B2VIS3
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

465817:ETA RS13430
gene id: 465817:ETA_RS13430
uniprot id: B2VBB3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465817:ETA RS10650
gene id: 465817:ETA_RS10650
uniprot id: B2VEF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS05605
gene id: 465817:ETA_RS05605
uniprot id: B2VHY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

465817:ETA RS08585
gene id: 465817:ETA_RS08585
uniprot id: B2VJ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

465817:ETA RS02880
gene id: 465817:ETA_RS02880
uniprot id: B2VGN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

465817:ETA RS11365
gene id: 465817:ETA_RS11365
uniprot id: B2VDJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MSOX/MTOX family. MTOX subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
messages: Monomer.

465817:ETA RS06295
gene id: 465817:ETA_RS06295
uniprot id: B2VE83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

465817:ETA RS11200
gene id: 465817:ETA_RS11200
uniprot id: B2VDK4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

465817:ETA RS02265
gene id: 465817:ETA_RS02265
uniprot id: B2VG47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

465817:ETA RS11570
gene id: 465817:ETA_RS11570
uniprot id: B2VDG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

465817:ETA RS01640
gene id: 465817:ETA_RS01640
uniprot id: B2VI98
names: Similarity
messages: Belongs to the VapB family.

465817:ETA RS11730
gene id: 465817:ETA_RS11730
uniprot id: B2VC93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS01730
gene id: 465817:ETA_RS01730
uniprot id: B2VG86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

465817:ETA RS17015
gene id: 465817:ETA_RS17015
uniprot id: B2VK62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

465817:ETA RS14180
gene id: 465817:ETA_RS14180
uniprot id: B2VIQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

465817:ETA RS13795
gene id: 465817:ETA_RS13795
uniprot id: B2VHS2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

465817:ETA RS06950
gene id: 465817:ETA_RS06950
uniprot id: B2VIW0
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

465817:ETA RS13700
gene id: 465817:ETA_RS13700
uniprot id: B2VHU5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

465817:ETA RS18005
gene id: 465817:ETA_RS18005
uniprot id: B2VJK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

465817:ETA RS05570
gene id: 465817:ETA_RS05570
uniprot id: B2VE20
names: Similarity
messages: Belongs to the skp family.

465817:ETA RS16765
gene id: 465817:ETA_RS16765
uniprot id: B2VKB3
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS05150
gene id: 465817:ETA_RS05150
uniprot id: B2VHZ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

465817:ETA RS05730
gene id: 465817:ETA_RS05730
uniprot id: B2VDW5
names: Similarity
messages: Belongs to the thioredoxin family.

465817:ETA RS05115
gene id: 465817:ETA_RS05115
uniprot id: B2VD61
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

465817:ETA RS07695
gene id: 465817:ETA_RS07695
uniprot id: B2VFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS14825
gene id: 465817:ETA_RS14825
uniprot id: B2VFZ4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

465817:ETA RS15655
gene id: 465817:ETA_RS15655
uniprot id: B2VDD4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

465817:ETA RS18180
gene id: 465817:ETA_RS18180
uniprot id: B2VCI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

465817:ETA RS06335
gene id: 465817:ETA_RS06335
uniprot id: B2VE68
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

465817:ETA RS02390
gene id: 465817:ETA_RS02390
uniprot id: B2VGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

465817:ETA RS02235
gene id: 465817:ETA_RS02235
uniprot id: B2VI65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

465817:ETA RS02825
gene id: 465817:ETA_RS02825
uniprot id: B2VGT3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS01620
gene id: 465817:ETA_RS01620
uniprot id: B2VI93
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

465817:ETA RS07765
gene id: 465817:ETA_RS07765
uniprot id: B2VFQ2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

465817:ETA RS15640
gene id: 465817:ETA_RS15640
uniprot id: B2VDC9
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

465817:ETA RS14815
gene id: 465817:ETA_RS14815
uniprot id: B2VFZ2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

465817:ETA RS02280
gene id: 465817:ETA_RS02280
uniprot id: B2VG44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

465817:ETA RS08240
gene id: 465817:ETA_RS08240
uniprot id: B2VES9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

465817:ETA RS12560
gene id: 465817:ETA_RS12560
uniprot id: B2VBT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

465817:ETA RS05030
gene id: 465817:ETA_RS05030
uniprot id: B2VI02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
messages: Membrane

465817:ETA RS02380
gene id: 465817:ETA_RS02380
uniprot id: B2VH00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS01315
gene id: 465817:ETA_RS01315
uniprot id: B2VF81
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

465817:ETA RS13440
gene id: 465817:ETA_RS13440
uniprot id: B2VBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Membrane

465817:ETA RS12155
gene id: 465817:ETA_RS12155
uniprot id: B2VBZ5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

465817:ETA RS06955
gene id: 465817:ETA_RS06955
uniprot id: B2VIW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

465817:ETA RS09940
gene id: 465817:ETA_RS09940
uniprot id: B2VK11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

465817:ETA RS05280
gene id: 465817:ETA_RS05280
uniprot id: B2VD32
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

465817:ETA RS05810
gene id: 465817:ETA_RS05810
uniprot id: B2VDV3
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

465817:ETA RS04560
gene id: 465817:ETA_RS04560
uniprot id: B2VH09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

465817:ETA RS16770
gene id: 465817:ETA_RS16770
uniprot id: B2VKB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

465817:ETA RS02575
gene id: 465817:ETA_RS02575
uniprot id: B2VGW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

465817:ETA RS11595
gene id: 465817:ETA_RS11595
uniprot id: B2VDG9
names: Similarity
messages: Belongs to the UPF0319 family.

465817:ETA RS12220
gene id: 465817:ETA_RS12220
uniprot id: B2VC08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

465817:ETA RS07860
gene id: 465817:ETA_RS07860
uniprot id: B2VFL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

465817:ETA RS18600
gene id: 465817:ETA_RS18600
uniprot id: B2VCB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

465817:ETA RS16900
gene id: 465817:ETA_RS16900
uniprot id: B2VK70
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

465817:ETA RS07335
gene id: 465817:ETA_RS07335
uniprot id: B2VIL1
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

465817:ETA RS12130
gene id: 465817:ETA_RS12130
uniprot id: B2VC30
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

465817:ETA RS13210
gene id: 465817:ETA_RS13210
uniprot id: B2VBH8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465817:ETA RS11320
gene id: 465817:ETA_RS11320
uniprot id: B2VIC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

465817:ETA RS13600
gene id: 465817:ETA_RS13600
uniprot id: B2VHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

465817:ETA RS06790
gene id: 465817:ETA_RS06790
uniprot id: B2VJ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

465817:ETA RS07480
gene id: 465817:ETA_RS07480
uniprot id: B2VIH3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS12810
gene id: 465817:ETA_RS12810
uniprot id: B2VBN7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

465817:ETA RS07015
gene id: 465817:ETA_RS07015
uniprot id: B2VIX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS14680
gene id: 465817:ETA_RS14680
uniprot id: B2VG25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

465817:ETA RS12400
gene id: 465817:ETA_RS12400
uniprot id: B2VBW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

465817:ETA RS05275
gene id: 465817:ETA_RS05275
uniprot id: B2VD31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

465817:ETA RS03640
gene id: 465817:ETA_RS03640
uniprot id: B2VGE1
names: Function
names: Similarity
messages: Belongs to the class-C beta-lactamase family.
messages: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.

465817:ETA RS10150
gene id: 465817:ETA_RS10150
uniprot id: B2VEN1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS01625
gene id: 465817:ETA_RS01625
uniprot id: B2VI94
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

465817:ETA RS11220
gene id: 465817:ETA_RS11220
uniprot id: B2VDK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

465817:ETA RS10500
gene id: 465817:ETA_RS10500
uniprot id: B2VEI8
names: Similarity
messages: Belongs to the UPF0162 family.

465817:ETA RS06470
gene id: 465817:ETA_RS06470
uniprot id: B2VI12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

465817:ETA RS16490
gene id: 465817:ETA_RS16490
uniprot id: B2VKG0
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

465817:ETA RS16080
gene id: 465817:ETA_RS16080
uniprot id: B2VCV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

465817:ETA RS10755
gene id: 465817:ETA_RS10755
uniprot id: B2VDT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

465817:ETA RS07325
gene id: 465817:ETA_RS07325
uniprot id: B2VIK9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465817:ETA RS03500
gene id: 465817:ETA_RS03500
uniprot id: B2VGF7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

465817:ETA RS11575
gene id: 465817:ETA_RS11575
uniprot id: B2VDG2
names: Similarity
messages: Belongs to the acylphosphatase family.

465817:ETA RS15760
gene id: 465817:ETA_RS15760
uniprot id: B2VDC2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS02920
gene id: 465817:ETA_RS02920
uniprot id: B2VGP4
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

465817:ETA RS04685
gene id: 465817:ETA_RS04685
uniprot id: B2VH06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

465817:ETA RS03805
gene id: 465817:ETA_RS03805
uniprot id: B2VJH5
names: Similarity
messages: Belongs to the polysaccharide lyase 3 family.

465817:ETA RS11075
gene id: 465817:ETA_RS11075
uniprot id: B2VDP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

465817:ETA RS10055
gene id: 465817:ETA_RS10055
uniprot id: B2VEN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

465817:ETA RS01320
gene id: 465817:ETA_RS01320
uniprot id: B2VF83
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

465817:ETA RS05380
gene id: 465817:ETA_RS05380
uniprot id: B2VCL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

465817:ETA RS05195
gene id: 465817:ETA_RS05195
uniprot id: B2VD41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

465817:ETA RS12110
gene id: 465817:ETA_RS12110
uniprot id: B2VC26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

465817:ETA RS01200
gene id: 465817:ETA_RS01200
uniprot id: B2VL59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

465817:ETA RS04605
gene id: 465817:ETA_RS04605
uniprot id: B2VH20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

465817:ETA RS08300
gene id: 465817:ETA_RS08300
uniprot id: B2VJE0
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

465817:ETA RS06965
gene id: 465817:ETA_RS06965
uniprot id: B2VIW4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS14420
gene id: 465817:ETA_RS14420
uniprot id: B2VHD9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

465817:ETA RS07025
gene id: 465817:ETA_RS07025
uniprot id: B2VIX6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

465817:ETA RS01630
gene id: 465817:ETA_RS01630
uniprot id: B2VI95
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

465817:ETA RS11805
gene id: 465817:ETA_RS11805
uniprot id: B2VC74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

465817:ETA RS15780
gene id: 465817:ETA_RS15780
uniprot id: B2VDC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

465817:ETA RS16300
gene id: 465817:ETA_RS16300
uniprot id: B2VCT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS18455
gene id: 465817:ETA_RS18455
uniprot id: B2VCE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

465817:ETA RS02610
gene id: 465817:ETA_RS02610
uniprot id: B2VGW8
names: Similarity
messages: Belongs to the peptidase S1C family.

465817:ETA RS04450
gene id: 465817:ETA_RS04450
uniprot id: B2VH53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

465817:ETA RS12790
gene id: 465817:ETA_RS12790
uniprot id: B2VBN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS16990
gene id: 465817:ETA_RS16990
uniprot id: B2VK57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

465817:ETA RS07845
gene id: 465817:ETA_RS07845
uniprot id: B2VFL3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

465817:ETA RS11775
gene id: 465817:ETA_RS11775
uniprot id: B2VCA2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

465817:ETA RS11060
gene id: 465817:ETA_RS11060
uniprot id: B2VDP4
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

465817:ETA RS17200
gene id: 465817:ETA_RS17200
uniprot id: B2VJW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS13085
gene id: 465817:ETA_RS13085
uniprot id: B2VBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane

465817:ETA RS07370
gene id: 465817:ETA_RS07370
uniprot id: B2VII5
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: To H.influenzae HI_0842.

465817:ETA RS10005
gene id: 465817:ETA_RS10005
uniprot id: B2VEQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

465817:ETA RS05105
gene id: 465817:ETA_RS05105
uniprot id: B2VD57
names: Similarity
messages: Belongs to the GSP E family.

465817:ETA RS12430
gene id: 465817:ETA_RS12430
uniprot id: B2VBX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS02150
gene id: 465817:ETA_RS02150
uniprot id: B2VG55
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

465817:ETA RS01870
gene id: 465817:ETA_RS01870
uniprot id: B2VG83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

465817:ETA RS10995
gene id: 465817:ETA_RS10995
uniprot id: B2VDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

465817:ETA RS18845
gene id: 465817:ETA_RS18845
uniprot id: B2VIC9
names: Subcellular Location Annotation
messages: target cell cytoplasm

465817:ETA RS16100
gene id: 465817:ETA_RS16100
uniprot id: B2VL81
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

465817:ETA RS12550
gene id: 465817:ETA_RS12550
uniprot id: B2VBT1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS10280
gene id: 465817:ETA_RS10280
uniprot id: B2VEL5
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

465817:ETA RS05040
gene id: 465817:ETA_RS05040
uniprot id: B2VI04
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS04455
gene id: 465817:ETA_RS04455
uniprot id: B2VH25
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

465817:ETA RS08750
gene id: 465817:ETA_RS08750
uniprot id: B2VJ65
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

465817:ETA RS15710
gene id: 465817:ETA_RS15710
uniprot id: B2VDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

465817:ETA RS06685
gene id: 465817:ETA_RS06685
uniprot id: B2VDY1
names: Similarity
messages: Belongs to the universal stress protein A family.

465817:ETA RS08940
gene id: 465817:ETA_RS08940
uniprot id: B2VKW1
names: Similarity
messages: Belongs to the asparaginase 1 family.

465817:ETA RS06985
gene id: 465817:ETA_RS06985
uniprot id: B2VIW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

465817:ETA RS12670
gene id: 465817:ETA_RS12670
uniprot id: B2VBR9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

465817:ETA RS12445
gene id: 465817:ETA_RS12445
uniprot id: B2VBT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

465817:ETA RS18320
gene id: 465817:ETA_RS18320
uniprot id: B2VCF3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS11870
gene id: 465817:ETA_RS11870
uniprot id: B2VC55
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

465817:ETA RS14620
gene id: 465817:ETA_RS14620
uniprot id: B2VG13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

465817:ETA RS11935
gene id: 465817:ETA_RS11935
uniprot id: B2VC68
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell inner membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

465817:ETA RS04680
gene id: 465817:ETA_RS04680
uniprot id: B2VH04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

465817:ETA RS08800
gene id: 465817:ETA_RS08800
uniprot id: B2VJ42
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

465817:ETA RS13885
gene id: 465817:ETA_RS13885
uniprot id: B2VHR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

465817:ETA RS18325
gene id: 465817:ETA_RS18325
uniprot id: B2VCF4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

465817:ETA RS02980
gene id: 465817:ETA_RS02980
uniprot id: B2VL42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

465817:ETA RS08590
gene id: 465817:ETA_RS08590
uniprot id: B2VJ97
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS11710
gene id: 465817:ETA_RS11710
uniprot id: B2VC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS03255
gene id: 465817:ETA_RS03255
uniprot id: B2VGJ9
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

465817:ETA RS16975
gene id: 465817:ETA_RS16975
uniprot id: B2VK54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

465817:ETA RS06775
gene id: 465817:ETA_RS06775
uniprot id: B2VJ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

465817:ETA RS05540
gene id: 465817:ETA_RS05540
uniprot id: B2VE11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

465817:ETA RS14245
gene id: 465817:ETA_RS14245
uniprot id: B2VHL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS07635
gene id: 465817:ETA_RS07635
uniprot id: B2VFQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.

465817:ETA RS15195
gene id: 465817:ETA_RS15195
uniprot id: B2VF34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

465817:ETA RS03385
gene id: 465817:ETA_RS03385
uniprot id: B2VGG1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS17615
gene id: 465817:ETA_RS17615
uniprot id: B2VJP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

465817:ETA RS17520
gene id: 465817:ETA_RS17520
uniprot id: B2VJQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

465817:ETA RS10330
gene id: 465817:ETA_RS10330
uniprot id: B2VEM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS04995
gene id: 465817:ETA_RS04995
uniprot id: B2VHZ5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

465817:ETA RS14545
gene id: 465817:ETA_RS14545
uniprot id: B2VHD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

465817:ETA RS05845
gene id: 465817:ETA_RS05845
uniprot id: B2VEE2
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS14890
gene id: 465817:ETA_RS14890
uniprot id: B2VFX9
names: Similarity
messages: Belongs to the SufE family.

465817:ETA RS11125
gene id: 465817:ETA_RS11125
uniprot id: B2VDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

465817:ETA RS15960
gene id: 465817:ETA_RS15960
uniprot id: B2VCW1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

465817:ETA RS16860
gene id: 465817:ETA_RS16860
uniprot id: B2VK93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

465817:ETA RS14900
gene id: 465817:ETA_RS14900
uniprot id: B2VFY1
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

465817:ETA RS17230
gene id: 465817:ETA_RS17230
uniprot id: B2VJW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS17530
gene id: 465817:ETA_RS17530
uniprot id: B2VJQ4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

465817:ETA RS10100
gene id: 465817:ETA_RS10100
uniprot id: B2VEP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS02290
gene id: 465817:ETA_RS02290
uniprot id: B2VG46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

465817:ETA RS04915
gene id: 465817:ETA_RS04915
uniprot id: B2VD72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecM family.
messages: Periplasm
messages: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
messages: cytosol

465817:ETA RS03915
gene id: 465817:ETA_RS03915
uniprot id: B2VHC0
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

465817:ETA RS11945
gene id: 465817:ETA_RS11945
uniprot id: B2VC34
names: Similarity
messages: Belongs to the UPF0145 family.

465817:ETA RS18195
gene id: 465817:ETA_RS18195
uniprot id: B2VCJ1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS13645
gene id: 465817:ETA_RS13645
uniprot id: B2VIT8
names: Similarity
messages: Belongs to the P(II) protein family.

465817:ETA RS02605
gene id: 465817:ETA_RS02605
uniprot id: B2VGW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

465817:ETA RS15255
gene id: 465817:ETA_RS15255
uniprot id: B2VF18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

465817:ETA RS14625
gene id: 465817:ETA_RS14625
uniprot id: B2VG14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

465817:ETA RS13055
gene id: 465817:ETA_RS13055
uniprot id: B2VBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane

465817:ETA RS03315
gene id: 465817:ETA_RS03315
uniprot id: B2VGI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS16030
gene id: 465817:ETA_RS16030
uniprot id: B2VCU8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

465817:ETA RS06655
gene id: 465817:ETA_RS06655
uniprot id: B2VE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

465817:ETA RS07090
gene id: 465817:ETA_RS07090
uniprot id: B2VIV2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS04720
gene id: 465817:ETA_RS04720
uniprot id: B2VGP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

465817:ETA RS07610
gene id: 465817:ETA_RS07610
uniprot id: B2VIG2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

465817:ETA RS15885
gene id: 465817:ETA_RS15885
uniprot id: B2VCX6
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS13390
gene id: 465817:ETA_RS13390
uniprot id: B2VBD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

465817:ETA RS02805
gene id: 465817:ETA_RS02805
uniprot id: B2VGT9
names: Similarity
messages: Belongs to the peptidase S13 family.

465817:ETA RS01410
gene id: 465817:ETA_RS01410
uniprot id: B2VL47
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

465817:ETA RS11770
gene id: 465817:ETA_RS11770
uniprot id: B2VCA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

465817:ETA RS07510
gene id: 465817:ETA_RS07510
uniprot id: B2VIH9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

465817:ETA RS08830
gene id: 465817:ETA_RS08830
uniprot id: B2VJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

465817:ETA RS12390
gene id: 465817:ETA_RS12390
uniprot id: B2VBW3
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

465817:ETA RS05890
gene id: 465817:ETA_RS05890
uniprot id: B2VED2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

465817:ETA RS07790
gene id: 465817:ETA_RS07790
uniprot id: B2VFN1
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

465817:ETA RS08000
gene id: 465817:ETA_RS08000
uniprot id: B2VFI8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS12975
gene id: 465817:ETA_RS12975
uniprot id: B2VBK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

465817:ETA RS05170
gene id: 465817:ETA_RS05170
uniprot id: B2VD36
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

465817:ETA RS07455
gene id: 465817:ETA_RS07455
uniprot id: B2VIG8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

465817:ETA RS04765
gene id: 465817:ETA_RS04765
uniprot id: B2VDA5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS14095
gene id: 465817:ETA_RS14095
uniprot id: B2VHL9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

465817:ETA RS05475
gene id: 465817:ETA_RS05475
uniprot id: B2VE25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS13985
gene id: 465817:ETA_RS13985
uniprot id: B2VIT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

465817:ETA RS04875
gene id: 465817:ETA_RS04875
uniprot id: B2VD91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

465817:ETA RS05555
gene id: 465817:ETA_RS05555
uniprot id: B2VE14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

465817:ETA RS13040
gene id: 465817:ETA_RS13040
uniprot id: B2VBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

465817:ETA RS12680
gene id: 465817:ETA_RS12680
uniprot id: B2VBS1
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

465817:ETA RS14125
gene id: 465817:ETA_RS14125
uniprot id: B2VHM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

465817:ETA RS06540
gene id: 465817:ETA_RS06540
uniprot id: B2VE47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

465817:ETA RS07670
gene id: 465817:ETA_RS07670
uniprot id: B2VFR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

465817:ETA RS02545
gene id: 465817:ETA_RS02545
uniprot id: B2VGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

465817:ETA RS04140
gene id: 465817:ETA_RS04140
uniprot id: B2VH72
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

465817:ETA RS06865
gene id: 465817:ETA_RS06865
uniprot id: B2VIY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

465817:ETA RS04600
gene id: 465817:ETA_RS04600
uniprot id: B2VH19
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

465817:ETA RS16800
gene id: 465817:ETA_RS16800
uniprot id: B2VK85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

465817:ETA RS08990
gene id: 465817:ETA_RS08990
uniprot id: B2VKX0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

465817:ETA RS02710
gene id: 465817:ETA_RS02710
uniprot id: B2VL64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

465817:ETA RS09215
gene id: 465817:ETA_RS09215
uniprot id: B2VKS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

465817:ETA RS11925
gene id: 465817:ETA_RS11925
uniprot id: B2VC66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

465817:ETA RS15320
gene id: 465817:ETA_RS15320
uniprot id: B2VF32
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

465817:ETA RS13725
gene id: 465817:ETA_RS13725
uniprot id: B2VHT8
names: Similarity
messages: Belongs to the BolA/IbaG family.

465817:ETA RS15945
gene id: 465817:ETA_RS15945
uniprot id: B2VCV8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

465817:ETA RS08605
gene id: 465817:ETA_RS08605
uniprot id: B2VJA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
messages: Cell inner membrane

465817:ETA RS14470
gene id: 465817:ETA_RS14470
uniprot id: B2VHI6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

465817:ETA RS11965
gene id: 465817:ETA_RS11965
uniprot id: B2VC38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

465817:ETA RS06565
gene id: 465817:ETA_RS06565
uniprot id: B2VE40
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

465817:ETA RS01790
gene id: 465817:ETA_RS01790
uniprot id: B2VG94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

465817:ETA RS13810
gene id: 465817:ETA_RS13810
uniprot id: B2VHS7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

465817:ETA RS02320
gene id: 465817:ETA_RS02320
uniprot id: B2VFE4
names: Similarity
messages: Belongs to the IMPACT family.

465817:ETA RS01990
gene id: 465817:ETA_RS01990
uniprot id: B2VI71
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

465817:ETA RS02480
gene id: 465817:ETA_RS02480
uniprot id: B2VL74
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

465817:ETA RS00070
gene id: 465817:ETA_RS00070
uniprot id: B2VAS3
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

465817:ETA RS19425
gene id: 465817:ETA_RS19425
uniprot id: B2VDD0
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

465817:ETA RS17135
gene id: 465817:ETA_RS17135
uniprot id: B2VK21
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

465817:ETA RS02155
gene id: 465817:ETA_RS02155
uniprot id: B2VG56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

465817:ETA RS12055
gene id: 465817:ETA_RS12055
uniprot id: B2VC16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

465817:ETA RS16855
gene id: 465817:ETA_RS16855
uniprot id: B2VK92
names: Similarity
messages: Belongs to the DprA/Smf family.

465817:ETA RS09565
gene id: 465817:ETA_RS09565
uniprot id: B2VKK6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

465817:ETA RS01685
gene id: 465817:ETA_RS01685
uniprot id: B2VGA1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

465817:ETA RS11820
gene id: 465817:ETA_RS11820
uniprot id: B2VC77
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

465817:ETA RS10190
gene id: 465817:ETA_RS10190
uniprot id: B2VEM9
names: Similarity
messages: Belongs to the pyruvate kinase family.

465817:ETA RS09290
gene id: 465817:ETA_RS09290
uniprot id: B2VKQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

465817:ETA RS10045
gene id: 465817:ETA_RS10045
uniprot id: B2VET3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

465817:ETA RS11390
gene id: 465817:ETA_RS11390
uniprot id: B2VDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

465817:ETA RS10035
gene id: 465817:ETA_RS10035
uniprot id: B2VET1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

465817:ETA RS02885
gene id: 465817:ETA_RS02885
uniprot id: B2VGN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

465817:ETA RS17575
gene id: 465817:ETA_RS17575
uniprot id: B2VJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

465817:ETA RS15385
gene id: 465817:ETA_RS15385
uniprot id: B2VF16
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465817:ETA RS16040
gene id: 465817:ETA_RS16040
uniprot id: B2VCV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

465817:ETA RS18385
gene id: 465817:ETA_RS18385
uniprot id: B2VCD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS09220
gene id: 465817:ETA_RS09220
uniprot id: B2VKS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

465817:ETA RS10305
gene id: 465817:ETA_RS10305
uniprot id: B2VEL3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

465817:ETA RS10395
gene id: 465817:ETA_RS10395
uniprot id: B2VEK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

465817:ETA RS02200
gene id: 465817:ETA_RS02200
uniprot id: B2VI57
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

465817:ETA RS13690
gene id: 465817:ETA_RS13690
uniprot id: B2VHU2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

465817:ETA RS10165
gene id: 465817:ETA_RS10165
uniprot id: B2VEM6
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

465817:ETA RS18345
gene id: 465817:ETA_RS18345
uniprot id: B2VCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

465817:ETA RS05920
gene id: 465817:ETA_RS05920
uniprot id: B2VEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

465817:ETA RS18200
gene id: 465817:ETA_RS18200
uniprot id: B2VCJ2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

465817:ETA RS01475
gene id: 465817:ETA_RS01475
uniprot id: B2VF62
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

465817:ETA RS05660
gene id: 465817:ETA_RS05660
uniprot id: B2VE02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

465817:ETA RS00340
gene id: 465817:ETA_RS00340
uniprot id: B2VAW1
names: Similarity
messages: Belongs to the GSP E family.

465817:ETA RS05650
gene id: 465817:ETA_RS05650
uniprot id: B2VDZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS14535
gene id: 465817:ETA_RS14535
uniprot id: B2VHD4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

465817:ETA RS07545
gene id: 465817:ETA_RS07545
uniprot id: B2VIE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

465817:ETA RS08475
gene id: 465817:ETA_RS08475
uniprot id: B2VJB0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

465817:ETA RS04440
gene id: 465817:ETA_RS04440
uniprot id: B2VH51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

465817:ETA RS07135
gene id: 465817:ETA_RS07135
uniprot id: B2VIN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465817:ETA RS01700
gene id: 465817:ETA_RS01700
uniprot id: B2VGA6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

465817:ETA RS07395
gene id: 465817:ETA_RS07395
uniprot id: B2VIJ0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

465817:ETA RS06140
gene id: 465817:ETA_RS06140
uniprot id: B2VI29
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

465817:ETA RS11830
gene id: 465817:ETA_RS11830
uniprot id: B2VC79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS06705
gene id: 465817:ETA_RS06705
uniprot id: B2VDX4
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS14175
gene id: 465817:ETA_RS14175
uniprot id: B2VIQ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465817:ETA RS03220
gene id: 465817:ETA_RS03220
uniprot id: B2VGJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

465817:ETA RS08470
gene id: 465817:ETA_RS08470
uniprot id: B2VJA9
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

465817:ETA RS08465
gene id: 465817:ETA_RS08465
uniprot id: B2VJA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS04615
gene id: 465817:ETA_RS04615
uniprot id: B2VGR2
names: Similarity
messages: Belongs to the UPF0246 family.

465817:ETA RS05025
gene id: 465817:ETA_RS05025
uniprot id: B2VI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS14155
gene id: 465817:ETA_RS14155
uniprot id: B2VIQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

465817:ETA RS16920
gene id: 465817:ETA_RS16920
uniprot id: B2VK74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

465817:ETA RS17060
gene id: 465817:ETA_RS17060
uniprot id: B2VK40
names: Similarity
messages: Belongs to the DsrF/TusC family.

465817:ETA RS04515
gene id: 465817:ETA_RS04515
uniprot id: B2VH33
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS02955
gene id: 465817:ETA_RS02955
uniprot id: B2VL37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

465817:ETA RS08905
gene id: 465817:ETA_RS08905
uniprot id: B2VJ31
names: Similarity
messages: Belongs to the MipA/OmpV family.

465817:ETA RS05990
gene id: 465817:ETA_RS05990
uniprot id: B2VI40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

465817:ETA RS15670
gene id: 465817:ETA_RS15670
uniprot id: B2VDD2
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

465817:ETA RS04810
gene id: 465817:ETA_RS04810
uniprot id: B2VDA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS01905
gene id: 465817:ETA_RS01905
uniprot id: B2VG78
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

465817:ETA RS17140
gene id: 465817:ETA_RS17140
uniprot id: B2VK22
names: Similarity
messages: Belongs to the UPF0270 family.

465817:ETA RS03345
gene id: 465817:ETA_RS03345
uniprot id: B2VGI7
names: Subunit
messages: Monomer.

465817:ETA RS12495
gene id: 465817:ETA_RS12495
uniprot id: B2VBU9
names: Similarity
messages: Belongs to the ModE family.

465817:ETA RS10730
gene id: 465817:ETA_RS10730
uniprot id: B2VIE3
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS15915
gene id: 465817:ETA_RS15915
uniprot id: B2VCY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

465817:ETA RS17215
gene id: 465817:ETA_RS17215
uniprot id: B2VJW5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465817:ETA RS08620
gene id: 465817:ETA_RS08620
uniprot id: B2VJA3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS08670
gene id: 465817:ETA_RS08670
uniprot id: B2VJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

465817:ETA RS07400
gene id: 465817:ETA_RS07400
uniprot id: B2VIJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS15625
gene id: 465817:ETA_RS15625
uniprot id: B2VL10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

465817:ETA RS11630
gene id: 465817:ETA_RS11630
uniprot id: B2VDE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer and homodimer.
messages: Required for conjugation with F-type plasmids; probably serves as the mating receptor on recipient cells.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

465817:ETA RS06215
gene id: 465817:ETA_RS06215
uniprot id: B2VE92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

465817:ETA RS04280
gene id: 465817:ETA_RS04280
uniprot id: B2VJF6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

465817:ETA RS06505
gene id: 465817:ETA_RS06505
uniprot id: B2VI19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

465817:ETA RS13120
gene id: 465817:ETA_RS13120
uniprot id: B2VBG1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS14140
gene id: 465817:ETA_RS14140
uniprot id: B2VHN2
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

465817:ETA RS13535
gene id: 465817:ETA_RS13535
uniprot id: B2VHX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

465817:ETA RS07570
gene id: 465817:ETA_RS07570
uniprot id: B2VIF4
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS07685
gene id: 465817:ETA_RS07685
uniprot id: B2VFR4
names: Similarity
messages: Belongs to the UPF0053 family.

465817:ETA RS13900
gene id: 465817:ETA_RS13900
uniprot id: B2VHR3
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

465817:ETA RS05975
gene id: 465817:ETA_RS05975
uniprot id: B2VI37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

465817:ETA RS17600
gene id: 465817:ETA_RS17600
uniprot id: B2VJN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

465817:ETA RS12475
gene id: 465817:ETA_RS12475
uniprot id: B2VBU5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS13970
gene id: 465817:ETA_RS13970
uniprot id: B2VIT0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family. AroL subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.
messages: The LID domain closes over the active site upon ATP binding.

465817:ETA RS10565
gene id: 465817:ETA_RS10565
uniprot id: B2VEG9
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS00230
gene id: 465817:ETA_RS00230
uniprot id: B2VAQ2
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS09255
gene id: 465817:ETA_RS09255
uniprot id: B2VKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

465817:ETA RS07855
gene id: 465817:ETA_RS07855
uniprot id: B2VFL5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

465817:ETA RS08955
gene id: 465817:ETA_RS08955
uniprot id: B2VKW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

465817:ETA RS05765
gene id: 465817:ETA_RS05765
uniprot id: B2VDW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS14030
gene id: 465817:ETA_RS14030
uniprot id: B2VHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS03175
gene id: 465817:ETA_RS03175
uniprot id: B2VL25
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

465817:ETA RS05155
gene id: 465817:ETA_RS05155
uniprot id: B2VHZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

465817:ETA RS15440
gene id: 465817:ETA_RS15440
uniprot id: B2VEZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

465817:ETA RS03280
gene id: 465817:ETA_RS03280
uniprot id: B2VGH5
names: Similarity
messages: Belongs to the UPF0441 family.

465817:ETA RS18095
gene id: 465817:ETA_RS18095
uniprot id: B2VCK7
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS15445
gene id: 465817:ETA_RS15445
uniprot id: B2VF00
names: Similarity
messages: Belongs to the transglycosylase Slt family.

465817:ETA RS08435
gene id: 465817:ETA_RS08435
uniprot id: B2VJD6
names: Similarity
messages: Belongs to the MotB family.

465817:ETA RS15920
gene id: 465817:ETA_RS15920
uniprot id: B2VCY5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

465817:ETA RS01540
gene id: 465817:ETA_RS01540
uniprot id: B2VER7
names: Similarity
messages: Belongs to the FBPase class 2 family.

465817:ETA RS12505
gene id: 465817:ETA_RS12505
uniprot id: B2VBV1
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

465817:ETA RS14235
gene id: 465817:ETA_RS14235
uniprot id: B2VHK9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

465817:ETA RS10945
gene id: 465817:ETA_RS10945
uniprot id: B2VDR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

465817:ETA RS14200
gene id: 465817:ETA_RS14200
uniprot id: B2VIR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

465817:ETA RS15365
gene id: 465817:ETA_RS15365
uniprot id: B2VF12
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

465817:ETA RS10240
gene id: 465817:ETA_RS10240
uniprot id: B2VJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

465817:ETA RS07170
gene id: 465817:ETA_RS07170
uniprot id: B2VIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS16295
gene id: 465817:ETA_RS16295
uniprot id: B2VCS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

465817:ETA RS07330
gene id: 465817:ETA_RS07330
uniprot id: B2VIL0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

465817:ETA RS11885
gene id: 465817:ETA_RS11885
uniprot id: B2VC58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

465817:ETA RS05045
gene id: 465817:ETA_RS05045
uniprot id: B2VI05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane
messages: Type II secretion system is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. Forms homomultimers.

465817:ETA RS05370
gene id: 465817:ETA_RS05370
uniprot id: B2VD20
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

465817:ETA RS07885
gene id: 465817:ETA_RS07885
uniprot id: B2VFM1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS15030
gene id: 465817:ETA_RS15030
uniprot id: B2VFV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

465817:ETA RS06795
gene id: 465817:ETA_RS06795
uniprot id: B2VJ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS13875
gene id: 465817:ETA_RS13875
uniprot id: B2VHQ8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

465817:ETA RS02465
gene id: 465817:ETA_RS02465
uniprot id: B2VL72
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

465817:ETA RS07435
gene id: 465817:ETA_RS07435
uniprot id: B2VIJ8
names: Similarity
messages: Belongs to the peptidase C40 family.

465817:ETA RS14670
gene id: 465817:ETA_RS14670
uniprot id: B2VG23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

465817:ETA RS15110
gene id: 465817:ETA_RS15110
uniprot id: B2VFT9
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS07115
gene id: 465817:ETA_RS07115
uniprot id: B2VIV7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

465817:ETA RS10545
gene id: 465817:ETA_RS10545
uniprot id: B2VEI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

465817:ETA RS05110
gene id: 465817:ETA_RS05110
uniprot id: B2VD58
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS14400
gene id: 465817:ETA_RS14400
uniprot id: B2VIQ0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

465817:ETA RS18450
gene id: 465817:ETA_RS18450
uniprot id: B2VCE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

465817:ETA RS05520
gene id: 465817:ETA_RS05520
uniprot id: B2VE19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

465817:ETA RS08490
gene id: 465817:ETA_RS08490
uniprot id: B2VJB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

465817:ETA RS02185
gene id: 465817:ETA_RS02185
uniprot id: B2VI54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

465817:ETA RS14635
gene id: 465817:ETA_RS14635
uniprot id: B2VG16
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body

465817:ETA RS15395
gene id: 465817:ETA_RS15395
uniprot id: B2VEZ0
names: Similarity
messages: Belongs to the GSP E family.

465817:ETA RS10380
gene id: 465817:ETA_RS10380
uniprot id: B2VEK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

465817:ETA RS18380
gene id: 465817:ETA_RS18380
uniprot id: B2VCD0
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS12345
gene id: 465817:ETA_RS12345
uniprot id: B2VBV4
names: Similarity
messages: Belongs to the peptidase S11 family.

465817:ETA RS08385
gene id: 465817:ETA_RS08385
uniprot id: B2VJC6
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

465817:ETA RS18185
gene id: 465817:ETA_RS18185
uniprot id: B2VCJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

465817:ETA RS02270
gene id: 465817:ETA_RS02270
uniprot id: B2VG39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

465817:ETA RS07130
gene id: 465817:ETA_RS07130
uniprot id: B2VIN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465817:ETA RS10975
gene id: 465817:ETA_RS10975
uniprot id: B2VDQ8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-94 and Arg-97) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

465817:ETA RS13865
gene id: 465817:ETA_RS13865
uniprot id: B2VHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

465817:ETA RS03200
gene id: 465817:ETA_RS03200
uniprot id: B2VL30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

465817:ETA RS15765
gene id: 465817:ETA_RS15765
uniprot id: B2VDC3
names: Similarity
messages: Belongs to the pirin family.

465817:ETA RS01970
gene id: 465817:ETA_RS01970
uniprot id: B2VI67
names: Similarity
messages: Belongs to the UPF0438 family.

465817:ETA RS09570
gene id: 465817:ETA_RS09570
uniprot id: B2VKK7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

465817:ETA RS18150
gene id: 465817:ETA_RS18150
uniprot id: B2VCI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS04750
gene id: 465817:ETA_RS04750
uniprot id: B2VGQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

465817:ETA RS05250
gene id: 465817:ETA_RS05250
uniprot id: B2VD29
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

465817:ETA RS08600
gene id: 465817:ETA_RS08600
uniprot id: B2VJ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

465817:ETA RS07645
gene id: 465817:ETA_RS07645
uniprot id: B2VFQ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC.

465817:ETA RS10415
gene id: 465817:ETA_RS10415
uniprot id: B2VJY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

465817:ETA RS17500
gene id: 465817:ETA_RS17500
uniprot id: B2VJS8
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

465817:ETA RS10020
gene id: 465817:ETA_RS10020
uniprot id: B2VEQ8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

465817:ETA RS06035
gene id: 465817:ETA_RS06035
uniprot id: B2VEA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

465817:ETA RS11330
gene id: 465817:ETA_RS11330
uniprot id: B2VDJ2
names: Similarity
messages: Belongs to the UPF0502 family.

465817:ETA RS17180
gene id: 465817:ETA_RS17180
uniprot id: B2VK30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TsgA family.
messages: Cell inner membrane

465817:ETA RS01645
gene id: 465817:ETA_RS01645
uniprot id: B2VGA2
names: Function
names: Similarity
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

465817:ETA RS10195
gene id: 465817:ETA_RS10195
uniprot id: B2VEN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

465817:ETA RS07415
gene id: 465817:ETA_RS07415
uniprot id: B2VIJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

465817:ETA RS13140
gene id: 465817:ETA_RS13140
uniprot id: B2VBG5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

465817:ETA RS04940
gene id: 465817:ETA_RS04940
uniprot id: B2VD70
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS08130
gene id: 465817:ETA_RS08130
uniprot id: B2VFF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

465817:ETA RS05340
gene id: 465817:ETA_RS05340
uniprot id: B2VD14
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

465817:ETA RS16760
gene id: 465817:ETA_RS16760
uniprot id: B2VKB2
names: Similarity
messages: Belongs to the aspartokinase family.

465817:ETA RS01550
gene id: 465817:ETA_RS01550
uniprot id: B2VER9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS12370
gene id: 465817:ETA_RS12370
uniprot id: B2VBV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

465817:ETA RS01335
gene id: 465817:ETA_RS01335
uniprot id: B2VF70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

465817:ETA RS18435
gene id: 465817:ETA_RS18435
uniprot id: B2VCE0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

465817:ETA RS12900
gene id: 465817:ETA_RS12900
uniprot id: B2VBM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS13395
gene id: 465817:ETA_RS13395
uniprot id: B2VBD9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

465817:ETA RS17990
gene id: 465817:ETA_RS17990
uniprot id: B2VJK1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS16245
gene id: 465817:ETA_RS16245
uniprot id: B2VCS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS14690
gene id: 465817:ETA_RS14690
uniprot id: B2VFZ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

465817:ETA RS05050
gene id: 465817:ETA_RS05050
uniprot id: B2VI06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

465817:ETA RS08610
gene id: 465817:ETA_RS08610
uniprot id: B2VJA1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS02260
gene id: 465817:ETA_RS02260
uniprot id: B2VG42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

465817:ETA RS05745
gene id: 465817:ETA_RS05745
uniprot id: B2VDW8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465817:ETA RS18775
gene id: 465817:ETA_RS18775
uniprot id: B2VH47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

465817:ETA RS13035
gene id: 465817:ETA_RS13035
uniprot id: B2VBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS07750
gene id: 465817:ETA_RS07750
uniprot id: B2VFP9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

465817:ETA RS11300
gene id: 465817:ETA_RS11300
uniprot id: B2VIB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

465817:ETA RS04105
gene id: 465817:ETA_RS04105
uniprot id: B2VH92
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS11985
gene id: 465817:ETA_RS11985
uniprot id: B2VC42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS13880
gene id: 465817:ETA_RS13880
uniprot id: B2VHQ9
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS15240
gene id: 465817:ETA_RS15240
uniprot id: B2VF43
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

465817:ETA RS15135
gene id: 465817:ETA_RS15135
uniprot id: B2VF48
names: Similarity
messages: Belongs to the RecJ family.

465817:ETA RS05355
gene id: 465817:ETA_RS05355
uniprot id: B2VD17
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

465817:ETA RS12485
gene id: 465817:ETA_RS12485
uniprot id: B2VBU7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

465817:ETA RS11905
gene id: 465817:ETA_RS11905
uniprot id: B2VC62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

465817:ETA RS04990
gene id: 465817:ETA_RS04990
uniprot id: B2VHZ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS13070
gene id: 465817:ETA_RS13070
uniprot id: B2VBI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane

465817:ETA RS08290
gene id: 465817:ETA_RS08290
uniprot id: B2VFF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
messages: Periplasm

465817:ETA RS17005
gene id: 465817:ETA_RS17005
uniprot id: B2VK60
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

465817:ETA RS07200
gene id: 465817:ETA_RS07200
uniprot id: B2VIL5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

465817:ETA RS12070
gene id: 465817:ETA_RS12070
uniprot id: B2VC19
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS07410
gene id: 465817:ETA_RS07410
uniprot id: B2VIJ3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS14715
gene id: 465817:ETA_RS14715
uniprot id: B2VG00
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

465817:ETA RS08890
gene id: 465817:ETA_RS08890
uniprot id: B2VJ28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS16105
gene id: 465817:ETA_RS16105
uniprot id: B2VL82
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

465817:ETA RS10060
gene id: 465817:ETA_RS10060
uniprot id: B2VEN5
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

465817:ETA RS13770
gene id: 465817:ETA_RS13770
uniprot id: B2VHS6
names: Similarity
messages: Belongs to the UPF0234 family.

465817:ETA RS12420
gene id: 465817:ETA_RS12420
uniprot id: B2VBW9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

465817:ETA RS15900
gene id: 465817:ETA_RS15900
uniprot id: B2VCX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

465817:ETA RS03515
gene id: 465817:ETA_RS03515
uniprot id: B2VKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS16705
gene id: 465817:ETA_RS16705
uniprot id: B2VKA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

465817:ETA RS10015
gene id: 465817:ETA_RS10015
uniprot id: B2VEQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

465817:ETA RS01590
gene id: 465817:ETA_RS01590
uniprot id: B2VI88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

465817:ETA RS01775
gene id: 465817:ETA_RS01775
uniprot id: B2VG91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

465817:ETA RS02500
gene id: 465817:ETA_RS02500
uniprot id: B2VL78
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

465817:ETA RS09370
gene id: 465817:ETA_RS09370
uniprot id: B2VKN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS03660
gene id: 465817:ETA_RS03660
uniprot id: B2VKY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

465817:ETA RS14160
gene id: 465817:ETA_RS14160
uniprot id: B2VIQ5
names: Similarity
messages: Belongs to the YkuD family.

465817:ETA RS09005
gene id: 465817:ETA_RS09005
uniprot id: B2VKX3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

465817:ETA RS18580
gene id: 465817:ETA_RS18580
uniprot id: B2VCA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

465817:ETA RS17020
gene id: 465817:ETA_RS17020
uniprot id: B2VK63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

465817:ETA RS06205
gene id: 465817:ETA_RS06205
uniprot id: B2VE90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS08925
gene id: 465817:ETA_RS08925
uniprot id: B2VJ36
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

465817:ETA RS15865
gene id: 465817:ETA_RS15865
uniprot id: B2VCY1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

465817:ETA RS05330
gene id: 465817:ETA_RS05330
uniprot id: B2VD09
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

465817:ETA RS13655
gene id: 465817:ETA_RS13655
uniprot id: B2VIU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

465817:ETA RS11305
gene id: 465817:ETA_RS11305
uniprot id: B2VIB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

465817:ETA RS11180
gene id: 465817:ETA_RS11180
uniprot id: B2VDK3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

465817:ETA RS05925
gene id: 465817:ETA_RS05925
uniprot id: B2VEC1
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

465817:ETA RS16240
gene id: 465817:ETA_RS16240
uniprot id: B2VCS6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

465817:ETA RS07080
gene id: 465817:ETA_RS07080
uniprot id: B2VIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS14595
gene id: 465817:ETA_RS14595
uniprot id: B2VG37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the invasin protein D family.
messages: Secreted

465817:ETA RS09415
gene id: 465817:ETA_RS09415
uniprot id: B2VKP2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

465817:ETA RS08065
gene id: 465817:ETA_RS08065
uniprot id: B2VFH3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS09350
gene id: 465817:ETA_RS09350
uniprot id: B2VKM9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

465817:ETA RS11315
gene id: 465817:ETA_RS11315
uniprot id: B2VIC0
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

465817:ETA RS05525
gene id: 465817:ETA_RS05525
uniprot id: B2VE05
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

465817:ETA RS03095
gene id: 465817:ETA_RS03095
uniprot id: B2VGK6
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS12040
gene id: 465817:ETA_RS12040
uniprot id: B2VC13
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS03340
gene id: 465817:ETA_RS03340
uniprot id: B2VGI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

465817:ETA RS15650
gene id: 465817:ETA_RS15650
uniprot id: B2VDD3
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS16460
gene id: 465817:ETA_RS16460
uniprot id: B2VKF4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS17515
gene id: 465817:ETA_RS17515
uniprot id: B2VJQ1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS12875
gene id: 465817:ETA_RS12875
uniprot id: B2VBL7
names: Similarity
messages: Belongs to the UPF0053 family.

465817:ETA RS11850
gene id: 465817:ETA_RS11850
uniprot id: B2VC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

465817:ETA RS01185
gene id: 465817:ETA_RS01185
uniprot id: B2VFB2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

465817:ETA RS07380
gene id: 465817:ETA_RS07380
uniprot id: B2VII7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

465817:ETA RS10515
gene id: 465817:ETA_RS10515
uniprot id: B2VEH7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

465817:ETA RS07120
gene id: 465817:ETA_RS07120
uniprot id: B2VIV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465817:ETA RS15455
gene id: 465817:ETA_RS15455
uniprot id: B2VF02
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

465817:ETA RS15950
gene id: 465817:ETA_RS15950
uniprot id: B2VCV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

465817:ETA RS05965
gene id: 465817:ETA_RS05965
uniprot id: B2VI35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

465817:ETA RS13465
gene id: 465817:ETA_RS13465
uniprot id: B2VBC0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

465817:ETA RS13850
gene id: 465817:ETA_RS13850
uniprot id: B2VHQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

465817:ETA RS11795
gene id: 465817:ETA_RS11795
uniprot id: B2VC72
names: Similarity
messages: Belongs to the UPF0434 family.

465817:ETA RS11755
gene id: 465817:ETA_RS11755
uniprot id: B2VC98
names: Similarity
messages: Belongs to the YkuD family.

465817:ETA RS06580
gene id: 465817:ETA_RS06580
uniprot id: B2VE45
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS08850
gene id: 465817:ETA_RS08850
uniprot id: B2VJ52
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

465817:ETA RS16910
gene id: 465817:ETA_RS16910
uniprot id: B2VK72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

465817:ETA RS15675
gene id: 465817:ETA_RS15675
uniprot id: B2VDD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

465817:ETA RS16780
gene id: 465817:ETA_RS16780
uniprot id: B2VKB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS03035
gene id: 465817:ETA_RS03035
uniprot id: B2VGL8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

465817:ETA RS02505
gene id: 465817:ETA_RS02505
uniprot id: B2VL79
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

465817:ETA RS15340
gene id: 465817:ETA_RS15340
uniprot id: B2VF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

465817:ETA RS17735
gene id: 465817:ETA_RS17735
uniprot id: B2VJM7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

465817:ETA RS11250
gene id: 465817:ETA_RS11250
uniprot id: B2VDL6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

465817:ETA RS14940
gene id: 465817:ETA_RS14940
uniprot id: B2VFW0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

465817:ETA RS02250
gene id: 465817:ETA_RS02250
uniprot id: B2VG40
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

465817:ETA RS17340
gene id: 465817:ETA_RS17340
uniprot id: B2VJW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

465817:ETA RS03745
gene id: 465817:ETA_RS03745
uniprot id: B2VGB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

465817:ETA RS17680
gene id: 465817:ETA_RS17680
uniprot id: B2VJL5
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS06475
gene id: 465817:ETA_RS06475
uniprot id: B2VI13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

465817:ETA RS01430
gene id: 465817:ETA_RS01430
uniprot id: B2VL51
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

465817:ETA RS09180
gene id: 465817:ETA_RS09180
uniprot id: B2VKR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

465817:ETA RS02490
gene id: 465817:ETA_RS02490
uniprot id: B2VL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

465817:ETA RS11080
gene id: 465817:ETA_RS11080
uniprot id: B2VDP8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

465817:ETA RS10025
gene id: 465817:ETA_RS10025
uniprot id: B2VER1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS02385
gene id: 465817:ETA_RS02385
uniprot id: B2VH01
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

465817:ETA RS08865
gene id: 465817:ETA_RS08865
uniprot id: B2VJ23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell inner membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

465817:ETA RS05935
gene id: 465817:ETA_RS05935
uniprot id: B2VEC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

465817:ETA RS11725
gene id: 465817:ETA_RS11725
uniprot id: B2VC92
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

465817:ETA RS14725
gene id: 465817:ETA_RS14725
uniprot id: B2VG02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

465817:ETA RS00090
gene id: 465817:ETA_RS00090
uniprot id: B2VAS7
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

465817:ETA RS04620
gene id: 465817:ETA_RS04620
uniprot id: B2VGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

465817:ETA RS13760
gene id: 465817:ETA_RS13760
uniprot id: B2VHR9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

465817:ETA RS02055
gene id: 465817:ETA_RS02055
uniprot id: B2VG63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS01290
gene id: 465817:ETA_RS01290
uniprot id: B2VF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

465817:ETA RS14455
gene id: 465817:ETA_RS14455
uniprot id: B2VHI1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

465817:ETA RS07155
gene id: 465817:ETA_RS07155
uniprot id: B2VIN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465817:ETA RS09855
gene id: 465817:ETA_RS09855
uniprot id: B2VET9
names: Similarity
messages: Belongs to the FAD-dependent urate hydroxylase family.

465817:ETA RS03785
gene id: 465817:ETA_RS03785
uniprot id: B2VJH1
names: Subcellular Location Annotation
messages: Secreted

465817:ETA RS13470
gene id: 465817:ETA_RS13470
uniprot id: B2VBC1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS09990
gene id: 465817:ETA_RS09990
uniprot id: B2VEQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

465817:ETA RS10390
gene id: 465817:ETA_RS10390
uniprot id: B2VEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

465817:ETA RS01390
gene id: 465817:ETA_RS01390
uniprot id: B2VF67
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS14845
gene id: 465817:ETA_RS14845
uniprot id: B2VFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

465817:ETA RS01800
gene id: 465817:ETA_RS01800
uniprot id: B2VG96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

465817:ETA RS04950
gene id: 465817:ETA_RS04950
uniprot id: B2VD73
names: Similarity
messages: Belongs to the YoeB family.

465817:ETA RS01490
gene id: 465817:ETA_RS01490
uniprot id: B2VF58
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS06780
gene id: 465817:ETA_RS06780
uniprot id: B2VJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

465817:ETA RS16085
gene id: 465817:ETA_RS16085
uniprot id: B2VCV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

465817:ETA RS13710
gene id: 465817:ETA_RS13710
uniprot id: B2VHU8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

465817:ETA RS09835
gene id: 465817:ETA_RS09835
uniprot id: B2VEU7
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

465817:ETA RS14395
gene id: 465817:ETA_RS14395
uniprot id: B2VIP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

465817:ETA RS05675
gene id: 465817:ETA_RS05675
uniprot id: B2VDZ5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS07010
gene id: 465817:ETA_RS07010
uniprot id: B2VIX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS11670
gene id: 465817:ETA_RS11670
uniprot id: B2VDF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

465817:ETA RS07700
gene id: 465817:ETA_RS07700
uniprot id: B2VFN9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

465817:ETA RS01190
gene id: 465817:ETA_RS01190
uniprot id: B2VFB3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS02755
gene id: 465817:ETA_RS02755
uniprot id: B2VGU5
names: Similarity
messages: Belongs to the BolA/IbaG family.

465817:ETA RS01350
gene id: 465817:ETA_RS01350
uniprot id: B2VF73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

465817:ETA RS13495
gene id: 465817:ETA_RS13495
uniprot id: B2VHW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS09295
gene id: 465817:ETA_RS09295
uniprot id: B2VKQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS02065
gene id: 465817:ETA_RS02065
uniprot id: B2VG65
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

465817:ETA RS18850
gene id: 465817:ETA_RS18850
uniprot id: B2VDM5
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

465817:ETA RS05385
gene id: 465817:ETA_RS05385
uniprot id: B2VCM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

465817:ETA RS01180
gene id: 465817:ETA_RS01180
uniprot id: B2VFB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

465817:ETA RS14405
gene id: 465817:ETA_RS14405
uniprot id: B2VIQ1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

465817:ETA RS02985
gene id: 465817:ETA_RS02985
uniprot id: B2VL43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

465817:ETA RS15165
gene id: 465817:ETA_RS15165
uniprot id: B2VFS2
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

465817:ETA RS14335
gene id: 465817:ETA_RS14335
uniprot id: B2VHJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

465817:ETA RS02475
gene id: 465817:ETA_RS02475
uniprot id: B2VL73
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

465817:ETA RS08845
gene id: 465817:ETA_RS08845
uniprot id: B2VJ51
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

465817:ETA RS03795
gene id: 465817:ETA_RS03795
uniprot id: B2VJH3
names: Similarity
messages: Belongs to the acetyltransferase YopJ family.

465817:ETA RS17105
gene id: 465817:ETA_RS17105
uniprot id: B2VK49
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS02875
gene id: 465817:ETA_RS02875
uniprot id: B2VGN4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

465817:ETA RS17835
gene id: 465817:ETA_RS17835
uniprot id: B2VHG1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

465817:ETA RS11240
gene id: 465817:ETA_RS11240
uniprot id: B2VDL2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

465817:ETA RS06830
gene id: 465817:ETA_RS06830
uniprot id: B2VJ10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

465817:ETA RS02145
gene id: 465817:ETA_RS02145
uniprot id: B2VG54
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

465817:ETA RS15405
gene id: 465817:ETA_RS15405
uniprot id: B2VEZ2
names: Similarity
messages: Belongs to the YggT family.

465817:ETA RS17270
gene id: 465817:ETA_RS17270
uniprot id: B2VJX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS11290
gene id: 465817:ETA_RS11290
uniprot id: B2VIB5
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

465817:ETA RS14220
gene id: 465817:ETA_RS14220
uniprot id: B2VHK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

465817:ETA RS14040
gene id: 465817:ETA_RS14040
uniprot id: B2VHP2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS02705
gene id: 465817:ETA_RS02705
uniprot id: B2VL63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

465817:ETA RS17330
gene id: 465817:ETA_RS17330
uniprot id: B2VJV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

465817:ETA RS05125
gene id: 465817:ETA_RS05125
uniprot id: B2VD63
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS02915
gene id: 465817:ETA_RS02915
uniprot id: B2VGP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

465817:ETA RS16930
gene id: 465817:ETA_RS16930
uniprot id: B2VK77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

465817:ETA RS13405
gene id: 465817:ETA_RS13405
uniprot id: B2VBA7
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS17625
gene id: 465817:ETA_RS17625
uniprot id: B2VJP2
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

465817:ETA RS06320
gene id: 465817:ETA_RS06320
uniprot id: B2VE69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS03215
gene id: 465817:ETA_RS03215
uniprot id: B2VGJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

465817:ETA RS18085
gene id: 465817:ETA_RS18085
uniprot id: B2VCK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

465817:ETA RS12690
gene id: 465817:ETA_RS12690
uniprot id: B2VBS3
names: Similarity
messages: Belongs to the citrate synthase family.

465817:ETA RS08190
gene id: 465817:ETA_RS08190
uniprot id: B2VFG7
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

465817:ETA RS17405
gene id: 465817:ETA_RS17405
uniprot id: B2VJU3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

465817:ETA RS06220
gene id: 465817:ETA_RS06220
uniprot id: B2VE93
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

465817:ETA RS18570
gene id: 465817:ETA_RS18570
uniprot id: B2VCA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

465817:ETA RS02775
gene id: 465817:ETA_RS02775
uniprot id: B2VGS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

465817:ETA RS03370
gene id: 465817:ETA_RS03370
uniprot id: B2VGG3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

465817:ETA RS02425
gene id: 465817:ETA_RS02425
uniprot id: B2VGY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

465817:ETA RS07810
gene id: 465817:ETA_RS07810
uniprot id: B2VFN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

465817:ETA RS00100
gene id: 465817:ETA_RS00100
uniprot id: B2VAS9
names: Function
names: Similarity
messages: Belongs to the GSP E family.
messages: Part of the Type IV secretion system.

465817:ETA RS16115
gene id: 465817:ETA_RS16115
uniprot id: B2VL84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

465817:ETA RS13845
gene id: 465817:ETA_RS13845
uniprot id: B2VHQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

465817:ETA RS02330
gene id: 465817:ETA_RS02330
uniprot id: B2VGZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Belongs to the flavodoxin family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

465817:ETA RS01825
gene id: 465817:ETA_RS01825
uniprot id: B2VI79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

465817:ETA RS12365
gene id: 465817:ETA_RS12365
uniprot id: B2VBV8
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

465817:ETA RS18245
gene id: 465817:ETA_RS18245
uniprot id: B2VCG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family.
messages: Cell inner membrane
messages: Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.

465817:ETA RS08425
gene id: 465817:ETA_RS08425
uniprot id: B2VJD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

465817:ETA RS01965
gene id: 465817:ETA_RS01965
uniprot id: B2VI66
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

465817:ETA RS06465
gene id: 465817:ETA_RS06465
uniprot id: B2VI11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

465817:ETA RS15995
gene id: 465817:ETA_RS15995
uniprot id: B2VCW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

465817:ETA RS14875
gene id: 465817:ETA_RS14875
uniprot id: B2VFX6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS12025
gene id: 465817:ETA_RS12025
uniprot id: B2VC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

465817:ETA RS00570
gene id: 465817:ETA_RS00570
uniprot id: B2VB05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TraA family.
messages: Cell inner membrane
messages: Membrane
messages: Monomer. Interacts with itself to form filaments; also interacts with TraQ.
messages: Secreted

465817:ETA RS02285
gene id: 465817:ETA_RS02285
uniprot id: B2VG45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS05390
gene id: 465817:ETA_RS05390
uniprot id: B2VCM1
names: Similarity
messages: Belongs to the SfsA family.

465817:ETA RS07490
gene id: 465817:ETA_RS07490
uniprot id: B2VIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

465817:ETA RS10365
gene id: 465817:ETA_RS10365
uniprot id: B2VEJ3
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS05345
gene id: 465817:ETA_RS05345
uniprot id: B2VD15
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS12950
gene id: 465817:ETA_RS12950
uniprot id: B2VBJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

465817:ETA RS10110
gene id: 465817:ETA_RS10110
uniprot id: B2VEP5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS06110
gene id: 465817:ETA_RS06110
uniprot id: B2VI23
names: Similarity
messages: Belongs to the P(II) protein family.

465817:ETA RS10495
gene id: 465817:ETA_RS10495
uniprot id: B2VEI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

465817:ETA RS05640
gene id: 465817:ETA_RS05640
uniprot id: B2VDZ7
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

465817:ETA RS03075
gene id: 465817:ETA_RS03075
uniprot id: B2VGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

465817:ETA RS10205
gene id: 465817:ETA_RS10205
uniprot id: B2VJZ2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

465817:ETA RS10520
gene id: 465817:ETA_RS10520
uniprot id: B2VEH8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

465817:ETA RS02170
gene id: 465817:ETA_RS02170
uniprot id: B2VI51
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

465817:ETA RS09395
gene id: 465817:ETA_RS09395
uniprot id: B2VKN8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

465817:ETA RS12080
gene id: 465817:ETA_RS12080
uniprot id: B2VC21
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

465817:ETA RS05545
gene id: 465817:ETA_RS05545
uniprot id: B2VE12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

465817:ETA RS02730
gene id: 465817:ETA_RS02730
uniprot id: B2VL68
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS11880
gene id: 465817:ETA_RS11880
uniprot id: B2VC57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

465817:ETA RS01340
gene id: 465817:ETA_RS01340
uniprot id: B2VF71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

465817:ETA RS16935
gene id: 465817:ETA_RS16935
uniprot id: B2VK78
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

465817:ETA RS06325
gene id: 465817:ETA_RS06325
uniprot id: B2VE70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS01575
gene id: 465817:ETA_RS01575
uniprot id: B2VF49
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

465817:ETA RS12775
gene id: 465817:ETA_RS12775
uniprot id: B2VBQ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS16130
gene id: 465817:ETA_RS16130
uniprot id: B2VL87
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

465817:ETA RS12665
gene id: 465817:ETA_RS12665
uniprot id: B2VBR8
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

465817:ETA RS11280
gene id: 465817:ETA_RS11280
uniprot id: B2VIB3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

465817:ETA RS07445
gene id: 465817:ETA_RS07445
uniprot id: B2VIG6
names: Similarity
messages: Belongs to the elongation factor P family.

465817:ETA RS12540
gene id: 465817:ETA_RS12540
uniprot id: B2VBS9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

465817:ETA RS13995
gene id: 465817:ETA_RS13995
uniprot id: B2VHN8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Binds 1 sodium ion per monomer.
messages: Binds 2 magnesium ions per monomer.
messages: Homotetramer.

465817:ETA RS10135
gene id: 465817:ETA_RS10135
uniprot id: B2VEQ0
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

465817:ETA RS00030
gene id: 465817:ETA_RS00030
uniprot id: B2VAP5
names: Similarity
messages: Belongs to the MobA/MobL family.

465817:ETA RS01155
gene id: 465817:ETA_RS01155
uniprot id: B2VFA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS18000
gene id: 465817:ETA_RS18000
uniprot id: B2VJK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

465817:ETA RS08295
gene id: 465817:ETA_RS08295
uniprot id: B2VJD9
names: Similarity
messages: Belongs to the PhoH family.

465817:ETA RS01325
gene id: 465817:ETA_RS01325
uniprot id: B2VF68
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

465817:ETA RS11035
gene id: 465817:ETA_RS11035
uniprot id: B2VDN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

465817:ETA RS11910
gene id: 465817:ETA_RS11910
uniprot id: B2VC63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

465817:ETA RS08100
gene id: 465817:ETA_RS08100
uniprot id: B2VFI0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

465817:ETA RS15020
gene id: 465817:ETA_RS15020
uniprot id: B2VFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

465817:ETA RS04675
gene id: 465817:ETA_RS04675
uniprot id: B2VH03
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

465817:ETA RS17465
gene id: 465817:ETA_RS17465
uniprot id: B2VJS3
names: Similarity
messages: Belongs to the pirin family.

465817:ETA RS11070
gene id: 465817:ETA_RS11070
uniprot id: B2VDP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

465817:ETA RS06510
gene id: 465817:ETA_RS06510
uniprot id: B2VI20
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

465817:ETA RS03695
gene id: 465817:ETA_RS03695
uniprot id: B2VKY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

465817:ETA RS05790
gene id: 465817:ETA_RS05790
uniprot id: B2VDW0
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

465817:ETA RS01055
gene id: 465817:ETA_RS01055
uniprot id: B2VFC2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

465817:ETA RS07220
gene id: 465817:ETA_RS07220
uniprot id: B2VIM0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.
messages: Belongs to the RcsC family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
messages: Interacts with RcsD.

465817:ETA RS05670
gene id: 465817:ETA_RS05670
uniprot id: B2VDZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465817:ETA RS09280
gene id: 465817:ETA_RS09280
uniprot id: B2VKP8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS15085
gene id: 465817:ETA_RS15085
uniprot id: B2VFT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

465817:ETA RS03940
gene id: 465817:ETA_RS03940
uniprot id: B2VH95
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

465817:ETA RS01665
gene id: 465817:ETA_RS01665
uniprot id: B2VGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

465817:ETA RS04565
gene id: 465817:ETA_RS04565
uniprot id: B2VH10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

465817:ETA RS11790
gene id: 465817:ETA_RS11790
uniprot id: B2VC71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

465817:ETA RS10990
gene id: 465817:ETA_RS10990
uniprot id: B2VDR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

465817:ETA RS08315
gene id: 465817:ETA_RS08315
uniprot id: B2VJE2
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

465817:ETA RS07205
gene id: 465817:ETA_RS07205
uniprot id: B2VIL6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

465817:ETA RS11430
gene id: 465817:ETA_RS11430
uniprot id: B2VDH8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465817:ETA RS02180
gene id: 465817:ETA_RS02180
uniprot id: B2VI53
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

465817:ETA RS09175
gene id: 465817:ETA_RS09175
uniprot id: B2VKR2
names: Similarity
messages: Belongs to the peptidase S49 family.

465817:ETA RS03755
gene id: 465817:ETA_RS03755
uniprot id: B2VGB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

465817:ETA RS13575
gene id: 465817:ETA_RS13575
uniprot id: B2VHV4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465817:ETA RS05530
gene id: 465817:ETA_RS05530
uniprot id: B2VE09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

465817:ETA RS16425
gene id: 465817:ETA_RS16425
uniprot id: B2VCN9
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

465817:ETA RS06945
gene id: 465817:ETA_RS06945
uniprot id: B2VJ00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

465817:ETA RS15700
gene id: 465817:ETA_RS15700
uniprot id: B2VDE1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

465817:ETA RS05575
gene id: 465817:ETA_RS05575
uniprot id: B2VHX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

465817:ETA RS05180
gene id: 465817:ETA_RS05180
uniprot id: B2VD38
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

465817:ETA RS03635
gene id: 465817:ETA_RS03635
uniprot id: B2VGE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS01140
gene id: 465817:ETA_RS01140
uniprot id: B2VFA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

465817:ETA RS00135
gene id: 465817:ETA_RS00135
uniprot id: B2VAT6
names: Similarity
messages: Belongs to the type IA topoisomerase family.

465817:ETA RS00400
gene id: 465817:ETA_RS00400
uniprot id: B2VAY6
names: Similarity
messages: Belongs to the type IA topoisomerase family.

465817:ETA RS17085
gene id: 465817:ETA_RS17085
uniprot id: B2VK45
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

465817:ETA RS06010
gene id: 465817:ETA_RS06010
uniprot id: B2VI44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

465817:ETA RS15330
gene id: 465817:ETA_RS15330
uniprot id: B2VF05
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

465817:ETA RS10465
gene id: 465817:ETA_RS10465
uniprot id: B2VJZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

465817:ETA RS17685
gene id: 465817:ETA_RS17685
uniprot id: B2VJL6
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS09210
gene id: 465817:ETA_RS09210
uniprot id: B2VKR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS18505
gene id: 465817:ETA_RS18505
uniprot id: B2VCC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

465817:ETA RS02090
gene id: 465817:ETA_RS02090
uniprot id: B2VG49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

465817:ETA RS10160
gene id: 465817:ETA_RS10160
uniprot id: B2VEM3
names: Similarity
messages: Belongs to the CFA/CMAS family.

465817:ETA RS01445
gene id: 465817:ETA_RS01445
uniprot id: B2VL54
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

465817:ETA RS10460
gene id: 465817:ETA_RS10460
uniprot id: B2VJY9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

465817:ETA RS05960
gene id: 465817:ETA_RS05960
uniprot id: B2VED1
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

465817:ETA RS14735
gene id: 465817:ETA_RS14735
uniprot id: B2VG04
names: Similarity
messages: Belongs to the YciI family.

465817:ETA RS04635
gene id: 465817:ETA_RS04635
uniprot id: B2VGR9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

465817:ETA RS12450
gene id: 465817:ETA_RS12450
uniprot id: B2VBU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS09065
gene id: 465817:ETA_RS09065
uniprot id: B2VKV2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

465817:ETA RS09490
gene id: 465817:ETA_RS09490
uniprot id: B2VKM4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asr family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Proteolytic processing gives rise to the active protein.
messages: Required for growth and/or survival at acidic conditions.

465817:ETA RS01465
gene id: 465817:ETA_RS01465
uniprot id: B2VF59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

465817:ETA RS13130
gene id: 465817:ETA_RS13130
uniprot id: B2VBG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

465817:ETA RS02865
gene id: 465817:ETA_RS02865
uniprot id: B2VGN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

465817:ETA RS03330
gene id: 465817:ETA_RS03330
uniprot id: B2VGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

465817:ETA RS02195
gene id: 465817:ETA_RS02195
uniprot id: B2VI56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

465817:ETA RS11190
gene id: 465817:ETA_RS11190
uniprot id: B2VDL5
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

465817:ETA RS16870
gene id: 465817:ETA_RS16870
uniprot id: B2VK95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

465817:ETA RS14860
gene id: 465817:ETA_RS14860
uniprot id: B2VFX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

465817:ETA RS18250
gene id: 465817:ETA_RS18250
uniprot id: B2VCH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

465817:ETA RS09000
gene id: 465817:ETA_RS09000
uniprot id: B2VKX2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

465817:ETA RS17555
gene id: 465817:ETA_RS17555
uniprot id: B2VJR1
names: Similarity
messages: Belongs to the leucine-binding protein family.

465817:ETA RS06395
gene id: 465817:ETA_RS06395
uniprot id: B2VE61
names: Similarity
messages: Belongs to the SAICAR synthetase family.

465817:ETA RS03265
gene id: 465817:ETA_RS03265
uniprot id: B2VGK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

465817:ETA RS15140
gene id: 465817:ETA_RS15140
uniprot id: B2VFR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

465817:ETA RS01565
gene id: 465817:ETA_RS01565
uniprot id: B2VES2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

465817:ETA RS02000
gene id: 465817:ETA_RS02000
uniprot id: B2VI73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

465817:ETA RS12000
gene id: 465817:ETA_RS12000
uniprot id: B2VC45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

465817:ETA RS07260
gene id: 465817:ETA_RS07260
uniprot id: B2VIM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS11215
gene id: 465817:ETA_RS11215
uniprot id: B2VDK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

465817:ETA RS00015
gene id: 465817:ETA_RS00015
uniprot id: B2VAP8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465817:ETA RS15305
gene id: 465817:ETA_RS15305
uniprot id: B2VF28
names: Similarity
messages: Belongs to the clavaminate synthase family.

465817:ETA RS08495
gene id: 465817:ETA_RS08495
uniprot id: B2VJB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

465817:ETA RS01975
gene id: 465817:ETA_RS01975
uniprot id: B2VI68
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

465817:ETA RS00140
gene id: 465817:ETA_RS00140
uniprot id: B2VAT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

465817:ETA RS05840
gene id: 465817:ETA_RS05840
uniprot id: B2VEE1
names: Similarity
messages: Belongs to the autoinducer synthase family.

465817:ETA RS12990
gene id: 465817:ETA_RS12990
uniprot id: B2VBK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.

465817:ETA RS17820
gene id: 465817:ETA_RS17820
uniprot id: B2VHF2
names: Similarity
messages: Belongs to the HsdR family.

465817:ETA RS05510
gene id: 465817:ETA_RS05510
uniprot id: B2VE16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm

465817:ETA RS17045
gene id: 465817:ETA_RS17045
uniprot id: B2VK37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

465817:ETA RS16985
gene id: 465817:ETA_RS16985
uniprot id: B2VK56
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

465817:ETA RS01295
gene id: 465817:ETA_RS01295
uniprot id: B2VF76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

465817:ETA RS16570
gene id: 465817:ETA_RS16570
uniprot id: B2VKE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

465817:ETA RS08810
gene id: 465817:ETA_RS08810
uniprot id: B2VJ44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

465817:ETA RS15720
gene id: 465817:ETA_RS15720
uniprot id: B2VDB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

465817:ETA RS09055
gene id: 465817:ETA_RS09055
uniprot id: B2VKV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

465817:ETA RS14785
gene id: 465817:ETA_RS14785
uniprot id: B2VFY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465817:ETA RS16925
gene id: 465817:ETA_RS16925
uniprot id: B2VK76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

465817:ETA RS16950
gene id: 465817:ETA_RS16950
uniprot id: B2VK81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

465817:ETA RS12715
gene id: 465817:ETA_RS12715
uniprot id: B2VBP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

465817:ETA RS05550
gene id: 465817:ETA_RS05550
uniprot id: B2VE13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

465817:ETA RS05160
gene id: 465817:ETA_RS05160
uniprot id: B2VD45
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS05940
gene id: 465817:ETA_RS05940
uniprot id: B2VEC4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

465817:ETA RS15735
gene id: 465817:ETA_RS15735
uniprot id: B2VDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS09775
gene id: 465817:ETA_RS09775
uniprot id: B2VEV1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS05775
gene id: 465817:ETA_RS05775
uniprot id: B2VDU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

465817:ETA RS17545
gene id: 465817:ETA_RS17545
uniprot id: B2VJQ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS04790
gene id: 465817:ETA_RS04790
uniprot id: B2VDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS16715
gene id: 465817:ETA_RS16715
uniprot id: B2VKA3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell inner membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

465817:ETA RS04640
gene id: 465817:ETA_RS04640
uniprot id: B2VGS0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

465817:ETA RS02820
gene id: 465817:ETA_RS02820
uniprot id: B2VGT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

465817:ETA RS13550
gene id: 465817:ETA_RS13550
uniprot id: B2VHV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

465817:ETA RS08165
gene id: 465817:ETA_RS08165
uniprot id: B2VFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtfA family.
messages: Cytoplasm
messages: Interacts with Mlc.
messages: Involved in the regulation of ptsG expression by binding and inactivating Mlc.

465817:ETA RS00105
gene id: 465817:ETA_RS00105
uniprot id: B2VAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

465817:ETA RS09965
gene id: 465817:ETA_RS09965
uniprot id: B2VK16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

465817:ETA RS16730
gene id: 465817:ETA_RS16730
uniprot id: B2VKA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS08915
gene id: 465817:ETA_RS08915
uniprot id: B2VJ33
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

465817:ETA RS04845
gene id: 465817:ETA_RS04845
uniprot id: B2VD88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

465817:ETA RS03230
gene id: 465817:ETA_RS03230
uniprot id: B2VGJ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

465817:ETA RS14565
gene id: 465817:ETA_RS14565
uniprot id: B2VG29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

465817:ETA RS06935
gene id: 465817:ETA_RS06935
uniprot id: B2VIZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

465817:ETA RS17930
gene id: 465817:ETA_RS17930
uniprot id: B2VHH5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465817:ETA RS12820
gene id: 465817:ETA_RS12820
uniprot id: B2VBN9
names: Similarity
messages: Belongs to the asparagine synthetase family.

465817:ETA RS02625
gene id: 465817:ETA_RS02625
uniprot id: B2VGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

465817:ETA RS16260
gene id: 465817:ETA_RS16260
uniprot id: B2VCR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

465817:ETA RS06835
gene id: 465817:ETA_RS06835
uniprot id: B2VJ11
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

465817:ETA RS01780
gene id: 465817:ETA_RS01780
uniprot id: B2VG92
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

465817:ETA RS13190
gene id: 465817:ETA_RS13190
uniprot id: B2VBH5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS13695
gene id: 465817:ETA_RS13695
uniprot id: B2VHU3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

465817:ETA RS02945
gene id: 465817:ETA_RS02945
uniprot id: B2VL35
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

465817:ETA RS02305
gene id: 465817:ETA_RS02305
uniprot id: B2VFE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

465817:ETA RS05680
gene id: 465817:ETA_RS05680
uniprot id: B2VDZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

465817:ETA RS12890
gene id: 465817:ETA_RS12890
uniprot id: B2VBM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465817:ETA RS13750
gene id: 465817:ETA_RS13750
uniprot id: B2VHU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

465817:ETA RS12660
gene id: 465817:ETA_RS12660
uniprot id: B2VBR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

465817:ETA RS00900
gene id: 465817:ETA_RS00900
uniprot id: B2VB65
names: Similarity
messages: Belongs to the ParB family.

465817:ETA RS18465
gene id: 465817:ETA_RS18465
uniprot id: B2VCE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

465817:ETA RS06640
gene id: 465817:ETA_RS06640
uniprot id: B2VDY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

465817:ETA RS10470
gene id: 465817:ETA_RS10470
uniprot id: B2VJZ1
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS08505
gene id: 465817:ETA_RS08505
uniprot id: B2VJB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS18280
gene id: 465817:ETA_RS18280
uniprot id: B2VCH7
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

465817:ETA RS05825
gene id: 465817:ETA_RS05825
uniprot id: B2VDV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

465817:ETA RS02570
gene id: 465817:ETA_RS02570
uniprot id: B2VGV9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465817:ETA RS14850
gene id: 465817:ETA_RS14850
uniprot id: B2VFX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS09985
gene id: 465817:ETA_RS09985
uniprot id: B2VEQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

465817:ETA RS08355
gene id: 465817:ETA_RS08355
uniprot id: B2VJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

465817:ETA RS15705
gene id: 465817:ETA_RS15705
uniprot id: B2VDE2
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS08340
gene id: 465817:ETA_RS08340
uniprot id: B2VJI8
names: Similarity
messages: Belongs to the CcdB toxin family.

465817:ETA RS07195
gene id: 465817:ETA_RS07195
uniprot id: B2VIP4
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

465817:ETA RS04695
gene id: 465817:ETA_RS04695
uniprot id: B2VGQ3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

465817:ETA RS12735
gene id: 465817:ETA_RS12735
uniprot id: B2VBP8
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

465817:ETA RS10050
gene id: 465817:ETA_RS10050
uniprot id: B2VEN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

465817:ETA RS18500
gene id: 465817:ETA_RS18500
uniprot id: B2VCB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS18090
gene id: 465817:ETA_RS18090
uniprot id: B2VCK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS10040
gene id: 465817:ETA_RS10040
uniprot id: B2VET2
names: Similarity
messages: Belongs to the GST superfamily.

465817:ETA RS02790
gene id: 465817:ETA_RS02790
uniprot id: B2VGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

465817:ETA RS17035
gene id: 465817:ETA_RS17035
uniprot id: B2VK35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

465817:ETA RS12920
gene id: 465817:ETA_RS12920
uniprot id: B2VBM6
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase HolA subunit family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.

465817:ETA RS08685
gene id: 465817:ETA_RS08685
uniprot id: B2VJ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

465817:ETA RS14185
gene id: 465817:ETA_RS14185
uniprot id: B2VIR0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

465817:ETA RS12940
gene id: 465817:ETA_RS12940
uniprot id: B2VBN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

465817:ETA RS15170
gene id: 465817:ETA_RS15170
uniprot id: B2VFS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

465817:ETA RS02370
gene id: 465817:ETA_RS02370
uniprot id: B2VGZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

465817:ETA RS14885
gene id: 465817:ETA_RS14885
uniprot id: B2VFX8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

465817:ETA RS13735
gene id: 465817:ETA_RS13735
uniprot id: B2VHU0
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS07550
gene id: 465817:ETA_RS07550
uniprot id: B2VIF0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465817:ETA RS14215
gene id: 465817:ETA_RS14215
uniprot id: B2VIR6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

465817:ETA RS08580
gene id: 465817:ETA_RS08580
uniprot id: B2VJ95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

465817:ETA RS01535
gene id: 465817:ETA_RS01535
uniprot id: B2VER6
names: Subcellular Location Annotation
messages: Membrane

465817:ETA RS06235
gene id: 465817:ETA_RS06235
uniprot id: B2VE99
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

465817:ETA RS17010
gene id: 465817:ETA_RS17010
uniprot id: B2VK61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

465817:ETA RS01600
gene id: 465817:ETA_RS01600
uniprot id: B2VI90
names: Similarity
messages: Belongs to the peptidase C59 family.

465817:ETA RS17165
gene id: 465817:ETA_RS17165
uniprot id: B2VK27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

465817:ETA RS12465
gene id: 465817:ETA_RS12465
uniprot id: B2VBU3
names: Function
names: Similarity
messages: Belongs to the cycloisomerase 2 family.
messages: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

465817:ETA RS01300
gene id: 465817:ETA_RS01300
uniprot id: B2VF77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

465817:ETA RS07385
gene id: 465817:ETA_RS07385
uniprot id: B2VII8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

465817:ETA RS14810
gene id: 465817:ETA_RS14810
uniprot id: B2VFZ1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

465817:ETA RS02770
gene id: 465817:ETA_RS02770
uniprot id: B2VGS8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

465817:ETA RS12870
gene id: 465817:ETA_RS12870
uniprot id: B2VBL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

465817:ETA RS04890
gene id: 465817:ETA_RS04890
uniprot id: B2VD94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

465817:ETA RS13820
gene id: 465817:ETA_RS13820
uniprot id: B2VHS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

465817:ETA RS11480
gene id: 465817:ETA_RS11480
uniprot id: B2VIA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

465817:ETA RS11405
gene id: 465817:ETA_RS11405
uniprot id: B2VDH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

465817:ETA RS16255
gene id: 465817:ETA_RS16255
uniprot id: B2VCT0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465817:ETA RS10660
gene id: 465817:ETA_RS10660
uniprot id: B2VEF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. T3SS SctC subfamily.
messages: Cell outer membrane
messages: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
messages: Membrane
messages: The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.