465721:ACG33 RS05090
gene id: 465721:ACG33_RS05090
uniprot id: A0A127F7R3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

465721:ACG33 RS07735
gene id: 465721:ACG33_RS07735
uniprot id: A0A127FBL3
names: Similarity
messages: Belongs to the fabD family.

465721:ACG33 RS07120
gene id: 465721:ACG33_RS07120
uniprot id: A0A127FB57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

465721:ACG33 RS09855
gene id: 465721:ACG33_RS09855
uniprot id: A0A127FAF4
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

465721:ACG33 RS03730
gene id: 465721:ACG33_RS03730
uniprot id: A0A127F9J5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS08240
gene id: 465721:ACG33_RS08240
uniprot id: A0A127F9J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

465721:ACG33 RS06560
gene id: 465721:ACG33_RS06560
uniprot id: A0A127F8L1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

465721:ACG33 RS05280
gene id: 465721:ACG33_RS05280
uniprot id: A0A127FAE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

465721:ACG33 RS05345
gene id: 465721:ACG33_RS05345
uniprot id: A0A127F7W3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

465721:ACG33 RS01205
gene id: 465721:ACG33_RS01205
uniprot id: A0A127F5P3
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

465721:ACG33 RS09515
gene id: 465721:ACG33_RS09515
uniprot id: A0A127FCM9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

465721:ACG33 RS00535
gene id: 465721:ACG33_RS00535
uniprot id: A0A127F5A3
names: Similarity
messages: Belongs to the Smg family.

465721:ACG33 RS15200
gene id: 465721:ACG33_RS15200
uniprot id: A0A127FDJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

465721:ACG33 RS00670
gene id: 465721:ACG33_RS00670
uniprot id: A0A127F7W2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465721:ACG33 RS11690
gene id: 465721:ACG33_RS11690
uniprot id: A0A127FBF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

465721:ACG33 RS11305
gene id: 465721:ACG33_RS11305
uniprot id: A0A127FDG8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

465721:ACG33 RS14810
gene id: 465721:ACG33_RS14810
uniprot id: A0A127FD73
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

465721:ACG33 RS00270
gene id: 465721:ACG33_RS00270
uniprot id: A0A127F7F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS14070
gene id: 465721:ACG33_RS14070
uniprot id: A0A127FCR6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS14795
gene id: 465721:ACG33_RS14795
uniprot id: A0A127FD71
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

465721:ACG33 RS09285
gene id: 465721:ACG33_RS09285
uniprot id: A0A127FA39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

465721:ACG33 RS00540
gene id: 465721:ACG33_RS00540
uniprot id: A0A127F594
names: Similarity
messages: Belongs to the DprA/Smf family.

465721:ACG33 RS02035
gene id: 465721:ACG33_RS02035
uniprot id: A0A127F8H5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS12670
gene id: 465721:ACG33_RS12670
uniprot id: A0A127FDX7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

465721:ACG33 RS05685
gene id: 465721:ACG33_RS05685
uniprot id: A0A127FAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

465721:ACG33 RS05590
gene id: 465721:ACG33_RS05590
uniprot id: A0A127FAE9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

465721:ACG33 RS07705
gene id: 465721:ACG33_RS07705
uniprot id: A0A127F991
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS01435
gene id: 465721:ACG33_RS01435
uniprot id: A0A127F5T0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

465721:ACG33 RS10310
gene id: 465721:ACG33_RS10310
uniprot id: A0A127FAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS15310
gene id: 465721:ACG33_RS15310
uniprot id: A0A127FDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

465721:ACG33 RS16470
gene id: 465721:ACG33_RS16470
uniprot id: A0A127F843
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

465721:ACG33 RS11190
gene id: 465721:ACG33_RS11190
uniprot id: A0A127FB55
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

465721:ACG33 RS09735
gene id: 465721:ACG33_RS09735
uniprot id: A0A127FAC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

465721:ACG33 RS08875
gene id: 465721:ACG33_RS08875
uniprot id: A0A127F9W1
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

465721:ACG33 RS02095
gene id: 465721:ACG33_RS02095
uniprot id: A0A127F688
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

465721:ACG33 RS13005
gene id: 465721:ACG33_RS13005
uniprot id: A0A127FDX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

465721:ACG33 RS00725
gene id: 465721:ACG33_RS00725
uniprot id: A0A127F7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS02325
gene id: 465721:ACG33_RS02325
uniprot id: A0A127F6A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

465721:ACG33 RS07250
gene id: 465721:ACG33_RS07250
uniprot id: A0A127FBC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

465721:ACG33 RS13550
gene id: 465721:ACG33_RS13550
uniprot id: A0A127FCI4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465721:ACG33 RS06780
gene id: 465721:ACG33_RS06780
uniprot id: A0A127F8R7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS14990
gene id: 465721:ACG33_RS14990
uniprot id: A0A127FDB8
names: Similarity
messages: Belongs to the DEAD box helicase family.

465721:ACG33 RS03550
gene id: 465721:ACG33_RS03550
uniprot id: A0A127F6Z5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS07760
gene id: 465721:ACG33_RS07760
uniprot id: A0A127F9A6
names: Subunit
messages: Homodimer.

465721:ACG33 RS10485
gene id: 465721:ACG33_RS10485
uniprot id: A0A127FAS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

465721:ACG33 RS11000
gene id: 465721:ACG33_RS11000
uniprot id: A0A127FDC4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

465721:ACG33 RS05075
gene id: 465721:ACG33_RS05075
uniprot id: A0A127F7Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS03040
gene id: 465721:ACG33_RS03040
uniprot id: A0A127F960
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

465721:ACG33 RS09805
gene id: 465721:ACG33_RS09805
uniprot id: A0A127FAE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465721:ACG33 RS14075
gene id: 465721:ACG33_RS14075
uniprot id: A0A127FEB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

465721:ACG33 RS09750
gene id: 465721:ACG33_RS09750
uniprot id: A0A127FCP3
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

465721:ACG33 RS07080
gene id: 465721:ACG33_RS07080
uniprot id: A0A127F8V5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

465721:ACG33 RS07245
gene id: 465721:ACG33_RS07245
uniprot id: A0A127F8Z2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

465721:ACG33 RS08445
gene id: 465721:ACG33_RS08445
uniprot id: A0A127FBY7
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

465721:ACG33 RS06825
gene id: 465721:ACG33_RS06825
uniprot id: A0A127F8Q4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS12125
gene id: 465721:ACG33_RS12125
uniprot id: A0A127FDR5
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

465721:ACG33 RS00475
gene id: 465721:ACG33_RS00475
uniprot id: A0A127F7K6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS08195
gene id: 465721:ACG33_RS08195
uniprot id: A0A127FBU0
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

465721:ACG33 RS03330
gene id: 465721:ACG33_RS03330
uniprot id: A0A127F6S2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS00360
gene id: 465721:ACG33_RS00360
uniprot id: A0A127F7R2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS04110
gene id: 465721:ACG33_RS04110
uniprot id: A0A127F773
names: Similarity
messages: Belongs to the GSP E family.

465721:ACG33 RS10330
gene id: 465721:ACG33_RS10330
uniprot id: A0A127FAN8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

465721:ACG33 RS09040
gene id: 465721:ACG33_RS09040
uniprot id: A0A127F9Y9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

465721:ACG33 RS11545
gene id: 465721:ACG33_RS11545
uniprot id: A0A127FDI4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

465721:ACG33 RS14850
gene id: 465721:ACG33_RS14850
uniprot id: A0A127FD89
names: Similarity
messages: Belongs to the TrpF family.

465721:ACG33 RS11285
gene id: 465721:ACG33_RS11285
uniprot id: A0A127FDF1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

465721:ACG33 RS09340
gene id: 465721:ACG33_RS09340
uniprot id: A0A127FA46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

465721:ACG33 RS14790
gene id: 465721:ACG33_RS14790
uniprot id: A0A127FD88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

465721:ACG33 RS10505
gene id: 465721:ACG33_RS10505
uniprot id: A0A127FD38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

465721:ACG33 RS04695
gene id: 465721:ACG33_RS04695
uniprot id: A0A127F7L1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

465721:ACG33 RS01740
gene id: 465721:ACG33_RS01740
uniprot id: A0A127F5Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

465721:ACG33 RS09370
gene id: 465721:ACG33_RS09370
uniprot id: A0A127FCJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

465721:ACG33 RS01530
gene id: 465721:ACG33_RS01530
uniprot id: A0A127F872
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

465721:ACG33 RS12280
gene id: 465721:ACG33_RS12280
uniprot id: A0A127FBR9
names: Similarity
messages: Belongs to the autoinducer synthase family.

465721:ACG33 RS10690
gene id: 465721:ACG33_RS10690
uniprot id: A0A127FAW2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

465721:ACG33 RS06975
gene id: 465721:ACG33_RS06975
uniprot id: A0A127F8U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

465721:ACG33 RS12475
gene id: 465721:ACG33_RS12475
uniprot id: A0A127FBV2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

465721:ACG33 RS12085
gene id: 465721:ACG33_RS12085
uniprot id: A0A127FBN2
names: Similarity
messages: Belongs to the CutA family.

465721:ACG33 RS06795
gene id: 465721:ACG33_RS06795
uniprot id: A0A127FB27
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

465721:ACG33 RS01480
gene id: 465721:ACG33_RS01480
uniprot id: A0A127F5T3
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

465721:ACG33 RS13955
gene id: 465721:ACG33_RS13955
uniprot id: A0A127FCS5
names: Similarity
messages: Belongs to the peptidase M16 family.

465721:ACG33 RS15405
gene id: 465721:ACG33_RS15405
uniprot id: A0A127FDN0
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS09715
gene id: 465721:ACG33_RS09715
uniprot id: A0A127FCQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

465721:ACG33 RS10230
gene id: 465721:ACG33_RS10230
uniprot id: A0A127FAM0
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

465721:ACG33 RS13665
gene id: 465721:ACG33_RS13665
uniprot id: A0A127FE93
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

465721:ACG33 RS09605
gene id: 465721:ACG33_RS09605
uniprot id: A0A127FAA3
names: Subcellular Location Annotation
messages: Cytoplasm

465721:ACG33 RS04250
gene id: 465721:ACG33_RS04250
uniprot id: A0A127F9R6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

465721:ACG33 RS10270
gene id: 465721:ACG33_RS10270
uniprot id: A0A127FD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

465721:ACG33 RS04385
gene id: 465721:ACG33_RS04385
uniprot id: A0A127F7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

465721:ACG33 RS04415
gene id: 465721:ACG33_RS04415
uniprot id: A0A127F9U8
names: Similarity
messages: Belongs to the PrpD family.

465721:ACG33 RS14745
gene id: 465721:ACG33_RS14745
uniprot id: A0A127FD58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS01670
gene id: 465721:ACG33_RS01670
uniprot id: A0A127F5W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

465721:ACG33 RS11265
gene id: 465721:ACG33_RS11265
uniprot id: A0A127FB82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

465721:ACG33 RS08865
gene id: 465721:ACG33_RS08865
uniprot id: A0A127FC45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

465721:ACG33 RS07630
gene id: 465721:ACG33_RS07630
uniprot id: A0A127FBJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

465721:ACG33 RS06925
gene id: 465721:ACG33_RS06925
uniprot id: A0A127FB61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465721:ACG33 RS03865
gene id: 465721:ACG33_RS03865
uniprot id: A0A127F754
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS00340
gene id: 465721:ACG33_RS00340
uniprot id: A0A127F7K2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS02345
gene id: 465721:ACG33_RS02345
uniprot id: A0A127F6F0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

465721:ACG33 RS00745
gene id: 465721:ACG33_RS00745
uniprot id: A0A127F7S7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465721:ACG33 RS01420
gene id: 465721:ACG33_RS01420
uniprot id: A0A127F5R4
names: Similarity
messages: Belongs to the GSP E family.

465721:ACG33 RS08145
gene id: 465721:ACG33_RS08145
uniprot id: A0A127FBT4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

465721:ACG33 RS13980
gene id: 465721:ACG33_RS13980
uniprot id: A0A127FCR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465721:ACG33 RS09185
gene id: 465721:ACG33_RS09185
uniprot id: A0A127FA21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

465721:ACG33 RS02560
gene id: 465721:ACG33_RS02560
uniprot id: A0A127F6J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

465721:ACG33 RS03140
gene id: 465721:ACG33_RS03140
uniprot id: A0A127F980
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS09420
gene id: 465721:ACG33_RS09420
uniprot id: A0A127FCK6
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

465721:ACG33 RS06880
gene id: 465721:ACG33_RS06880
uniprot id: A0A127F8R6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465721:ACG33 RS00735
gene id: 465721:ACG33_RS00735
uniprot id: A0A127F5F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

465721:ACG33 RS09520
gene id: 465721:ACG33_RS09520
uniprot id: A0A127FCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

465721:ACG33 RS14325
gene id: 465721:ACG33_RS14325
uniprot id: A0A127FCW9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

465721:ACG33 RS13625
gene id: 465721:ACG33_RS13625
uniprot id: A0A127FE75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS02540
gene id: 465721:ACG33_RS02540
uniprot id: A0A127F6F8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

465721:ACG33 RS02150
gene id: 465721:ACG33_RS02150
uniprot id: A0A127F8J7
names: Similarity
messages: Belongs to the XFP family.

465721:ACG33 RS03745
gene id: 465721:ACG33_RS03745
uniprot id: A0A127F701
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS00465
gene id: 465721:ACG33_RS00465
uniprot id: A0A127F7T5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

465721:ACG33 RS08970
gene id: 465721:ACG33_RS08970
uniprot id: A0A127F9X8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

465721:ACG33 RS03100
gene id: 465721:ACG33_RS03100
uniprot id: A0A127F8Z9
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

465721:ACG33 RS05195
gene id: 465721:ACG33_RS05195
uniprot id: A0A127F7T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

465721:ACG33 RS06515
gene id: 465721:ACG33_RS06515
uniprot id: A0A127FAY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

465721:ACG33 RS00570
gene id: 465721:ACG33_RS00570
uniprot id: A0A127F7U5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

465721:ACG33 RS06255
gene id: 465721:ACG33_RS06255
uniprot id: A0A127F8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

465721:ACG33 RS08690
gene id: 465721:ACG33_RS08690
uniprot id: A0A127FC25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

465721:ACG33 RS04265
gene id: 465721:ACG33_RS04265
uniprot id: A0A127F7B5
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS10490
gene id: 465721:ACG33_RS10490
uniprot id: A0A127FD41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

465721:ACG33 RS00790
gene id: 465721:ACG33_RS00790
uniprot id: A0A127F5E1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

465721:ACG33 RS01130
gene id: 465721:ACG33_RS01130
uniprot id: A0A127F853
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

465721:ACG33 RS13465
gene id: 465721:ACG33_RS13465
uniprot id: A0A127FE57
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

465721:ACG33 RS05900
gene id: 465721:ACG33_RS05900
uniprot id: A0A127FAR9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

465721:ACG33 RS13445
gene id: 465721:ACG33_RS13445
uniprot id: A0A127FCE8
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS04185
gene id: 465721:ACG33_RS04185
uniprot id: A0A127F7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

465721:ACG33 RS08065
gene id: 465721:ACG33_RS08065
uniprot id: A0A127FBU4
names: Cofactor
messages: Can also use Mn(2+) ion.

465721:ACG33 RS06875
gene id: 465721:ACG33_RS06875
uniprot id: A0A127FB51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465721:ACG33 RS01895
gene id: 465721:ACG33_RS01895
uniprot id: A0A127F629
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

465721:ACG33 RS00985
gene id: 465721:ACG33_RS00985
uniprot id: A0A127F5I0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

465721:ACG33 RS05225
gene id: 465721:ACG33_RS05225
uniprot id: A0A127FA79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

465721:ACG33 RS13795
gene id: 465721:ACG33_RS13795
uniprot id: A0A127FE91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465721:ACG33 RS04455
gene id: 465721:ACG33_RS04455
uniprot id: A0A127F9T6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465721:ACG33 RS14170
gene id: 465721:ACG33_RS14170
uniprot id: A0A127FCU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

465721:ACG33 RS08435
gene id: 465721:ACG33_RS08435
uniprot id: A0A127F9N6
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS11370
gene id: 465721:ACG33_RS11370
uniprot id: A0A127FB99
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS06545
gene id: 465721:ACG33_RS06545
uniprot id: A0A127FAU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

465721:ACG33 RS00225
gene id: 465721:ACG33_RS00225
uniprot id: A0A127F539
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS09045
gene id: 465721:ACG33_RS09045
uniprot id: A0A127F9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

465721:ACG33 RS00955
gene id: 465721:ACG33_RS00955
uniprot id: A0A127F5H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

465721:ACG33 RS12985
gene id: 465721:ACG33_RS12985
uniprot id: A0A127FC68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

465721:ACG33 RS04085
gene id: 465721:ACG33_RS04085
uniprot id: A0A127F7C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

465721:ACG33 RS09160
gene id: 465721:ACG33_RS09160
uniprot id: A0A127FCF1
names: Caution
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

465721:ACG33 RS10320
gene id: 465721:ACG33_RS10320
uniprot id: A0A127FD04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

465721:ACG33 RS05830
gene id: 465721:ACG33_RS05830
uniprot id: A0A127FAK5
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

465721:ACG33 RS02350
gene id: 465721:ACG33_RS02350
uniprot id: A0A127F8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

465721:ACG33 RS15195
gene id: 465721:ACG33_RS15195
uniprot id: A0A127FET4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

465721:ACG33 RS09660
gene id: 465721:ACG33_RS09660
uniprot id: A0A127FAB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

465721:ACG33 RS14390
gene id: 465721:ACG33_RS14390
uniprot id: A0A127FCY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS00895
gene id: 465721:ACG33_RS00895
uniprot id: A0A127F5G6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS13785
gene id: 465721:ACG33_RS13785
uniprot id: A0A127FE95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance.
messages: Periplasm

465721:ACG33 RS06765
gene id: 465721:ACG33_RS06765
uniprot id: A0A127F8Q2
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

465721:ACG33 RS09015
gene id: 465721:ACG33_RS09015
uniprot id: A0A127FC66
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

465721:ACG33 RS04605
gene id: 465721:ACG33_RS04605
uniprot id: A0A127F7L5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

465721:ACG33 RS05450
gene id: 465721:ACG33_RS05450
uniprot id: A0A127F7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS08885
gene id: 465721:ACG33_RS08885
uniprot id: A0A127FC83
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS11730
gene id: 465721:ACG33_RS11730
uniprot id: A0A127FBF5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465721:ACG33 RS11800
gene id: 465721:ACG33_RS11800
uniprot id: A0A127FDS2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS06735
gene id: 465721:ACG33_RS06735
uniprot id: A0A127FB68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

465721:ACG33 RS07825
gene id: 465721:ACG33_RS07825
uniprot id: A0A127F8U7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

465721:ACG33 RS08605
gene id: 465721:ACG33_RS08605
uniprot id: A0A127FC14
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

465721:ACG33 RS05740
gene id: 465721:ACG33_RS05740
uniprot id: A0A127FAI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

465721:ACG33 RS00195
gene id: 465721:ACG33_RS00195
uniprot id: A0A127F522
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

465721:ACG33 RS03165
gene id: 465721:ACG33_RS03165
uniprot id: A0A127F6S8
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

465721:ACG33 RS01745
gene id: 465721:ACG33_RS01745
uniprot id: A0A127F5Z7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

465721:ACG33 RS01395
gene id: 465721:ACG33_RS01395
uniprot id: A0A127F8A2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

465721:ACG33 RS07855
gene id: 465721:ACG33_RS07855
uniprot id: A0A127F9C3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS02870
gene id: 465721:ACG33_RS02870
uniprot id: A0A127F6P9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

465721:ACG33 RS15215
gene id: 465721:ACG33_RS15215
uniprot id: A0A127FES6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

465721:ACG33 RS02255
gene id: 465721:ACG33_RS02255
uniprot id: A0A127F8T1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS09745
gene id: 465721:ACG33_RS09745
uniprot id: A0A127FAC6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

465721:ACG33 RS12180
gene id: 465721:ACG33_RS12180
uniprot id: A0A127FBP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS05315
gene id: 465721:ACG33_RS05315
uniprot id: A0A127F7U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

465721:ACG33 RS04210
gene id: 465721:ACG33_RS04210
uniprot id: A0A127F793
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

465721:ACG33 RS08950
gene id: 465721:ACG33_RS08950
uniprot id: A0A127FCB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

465721:ACG33 RS01375
gene id: 465721:ACG33_RS01375
uniprot id: A0A127F847
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

465721:ACG33 RS08640
gene id: 465721:ACG33_RS08640
uniprot id: A0A127FC19
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

465721:ACG33 RS03195
gene id: 465721:ACG33_RS03195
uniprot id: A0A127F955
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS10940
gene id: 465721:ACG33_RS10940
uniprot id: A0A127FB07
names: Similarity
messages: Belongs to the MlaA family.

465721:ACG33 RS06625
gene id: 465721:ACG33_RS06625
uniprot id: A0A127F8N7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS06395
gene id: 465721:ACG33_RS06395
uniprot id: A0A127F8I1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

465721:ACG33 RS14380
gene id: 465721:ACG33_RS14380
uniprot id: A0A127FCW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465721:ACG33 RS05745
gene id: 465721:ACG33_RS05745
uniprot id: A0A127FAP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

465721:ACG33 RS09655
gene id: 465721:ACG33_RS09655
uniprot id: A0A127FAB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

465721:ACG33 RS11945
gene id: 465721:ACG33_RS11945
uniprot id: A0A127FDR2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

465721:ACG33 RS03065
gene id: 465721:ACG33_RS03065
uniprot id: A0A127F6Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Membrane

465721:ACG33 RS11110
gene id: 465721:ACG33_RS11110
uniprot id: A0A127FB56
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

465721:ACG33 RS04995
gene id: 465721:ACG33_RS04995
uniprot id: A0A127FA38
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS09145
gene id: 465721:ACG33_RS09145
uniprot id: A0A127FA08
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

465721:ACG33 RS05915
gene id: 465721:ACG33_RS05915
uniprot id: A0A127FAJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

465721:ACG33 RS09635
gene id: 465721:ACG33_RS09635
uniprot id: A0A127FAA5
names: Similarity
messages: Belongs to the skp family.

465721:ACG33 RS06535
gene id: 465721:ACG33_RS06535
uniprot id: A0A127FB29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS09080
gene id: 465721:ACG33_RS09080
uniprot id: A0A127F9Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

465721:ACG33 RS15295
gene id: 465721:ACG33_RS15295
uniprot id: A0A127FEV3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

465721:ACG33 RS02490
gene id: 465721:ACG33_RS02490
uniprot id: A0A127F6E7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

465721:ACG33 RS09210
gene id: 465721:ACG33_RS09210
uniprot id: A0A127FCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

465721:ACG33 RS12860
gene id: 465721:ACG33_RS12860
uniprot id: A0A127FE06
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

465721:ACG33 RS08350
gene id: 465721:ACG33_RS08350
uniprot id: A0A127F9K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

465721:ACG33 RS15020
gene id: 465721:ACG33_RS15020
uniprot id: A0A127FET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

465721:ACG33 RS06215
gene id: 465721:ACG33_RS06215
uniprot id: A0A127F8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS04175
gene id: 465721:ACG33_RS04175
uniprot id: A0A127F9N8
names: Similarity
messages: Belongs to the acylphosphatase family.

465721:ACG33 RS04310
gene id: 465721:ACG33_RS04310
uniprot id: A0A127F7B2
names: Similarity
messages: Belongs to the DprA/Smf family.

465721:ACG33 RS05215
gene id: 465721:ACG33_RS05215
uniprot id: A0A127F7T2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

465721:ACG33 RS02265
gene id: 465721:ACG33_RS02265
uniprot id: A0A127F8I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

465721:ACG33 RS10400
gene id: 465721:ACG33_RS10400
uniprot id: A0A127FCU4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

465721:ACG33 RS12210
gene id: 465721:ACG33_RS12210
uniprot id: A0A127FDV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

465721:ACG33 RS05725
gene id: 465721:ACG33_RS05725
uniprot id: A0A127F844
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

465721:ACG33 RS05230
gene id: 465721:ACG33_RS05230
uniprot id: A0A127FAD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

465721:ACG33 RS05645
gene id: 465721:ACG33_RS05645
uniprot id: A0A127FAK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

465721:ACG33 RS05575
gene id: 465721:ACG33_RS05575
uniprot id: A0A127FAE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

465721:ACG33 RS09305
gene id: 465721:ACG33_RS09305
uniprot id: A0A127FA41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

465721:ACG33 RS06080
gene id: 465721:ACG33_RS06080
uniprot id: A0A127FAL8
names: Subcellular Location Annotation
messages: Nucleus

465721:ACG33 RS07130
gene id: 465721:ACG33_RS07130
uniprot id: A0A127F8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

465721:ACG33 RS01965
gene id: 465721:ACG33_RS01965
uniprot id: A0A127F8C7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

465721:ACG33 RS09535
gene id: 465721:ACG33_RS09535
uniprot id: A0A127FA86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

465721:ACG33 RS07745
gene id: 465721:ACG33_RS07745
uniprot id: A0A127FBL2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

465721:ACG33 RS00355
gene id: 465721:ACG33_RS00355
uniprot id: A0A127F7K5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465721:ACG33 RS04565
gene id: 465721:ACG33_RS04565
uniprot id: A0A127FA01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

465721:ACG33 RS12495
gene id: 465721:ACG33_RS12495
uniprot id: A0A127FDW9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS10480
gene id: 465721:ACG33_RS10480
uniprot id: A0A127FAS1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

465721:ACG33 RS06335
gene id: 465721:ACG33_RS06335
uniprot id: A0A127FAU3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

465721:ACG33 RS10590
gene id: 465721:ACG33_RS10590
uniprot id: A0A127FAU0
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

465721:ACG33 RS07340
gene id: 465721:ACG33_RS07340
uniprot id: A0A127FB96
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS15165
gene id: 465721:ACG33_RS15165
uniprot id: A0A127FER8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS08185
gene id: 465721:ACG33_RS08185
uniprot id: A0A127F9I8
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

465721:ACG33 RS14150
gene id: 465721:ACG33_RS14150
uniprot id: A0A127FEB7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

465721:ACG33 RS05285
gene id: 465721:ACG33_RS05285
uniprot id: A0A127FAA1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

465721:ACG33 RS01695
gene id: 465721:ACG33_RS01695
uniprot id: A0A127F5Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS15390
gene id: 465721:ACG33_RS15390
uniprot id: A0A127FEV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

465721:ACG33 RS00525
gene id: 465721:ACG33_RS00525
uniprot id: A0A127F7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

465721:ACG33 RS12980
gene id: 465721:ACG33_RS12980
uniprot id: A0A127FE10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

465721:ACG33 RS06630
gene id: 465721:ACG33_RS06630
uniprot id: A0A127FAZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS15455
gene id: 465721:ACG33_RS15455
uniprot id: A0A127FDP1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

465721:ACG33 RS01720
gene id: 465721:ACG33_RS01720
uniprot id: A0A127F5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

465721:ACG33 RS05180
gene id: 465721:ACG33_RS05180
uniprot id: A0A127FAC1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS06540
gene id: 465721:ACG33_RS06540
uniprot id: A0A127FAY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

465721:ACG33 RS01450
gene id: 465721:ACG33_RS01450
uniprot id: A0A127F8B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

465721:ACG33 RS05255
gene id: 465721:ACG33_RS05255
uniprot id: A0A127F7W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

465721:ACG33 RS07620
gene id: 465721:ACG33_RS07620
uniprot id: A0A127F972
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

465721:ACG33 RS06380
gene id: 465721:ACG33_RS06380
uniprot id: A0A127FB05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

465721:ACG33 RS06500
gene id: 465721:ACG33_RS06500
uniprot id: A0A127F8J2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS03980
gene id: 465721:ACG33_RS03980
uniprot id: A0A127F7A1
names: Similarity
messages: Belongs to the universal stress protein A family.

465721:ACG33 RS14195
gene id: 465721:ACG33_RS14195
uniprot id: A0A127FEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

465721:ACG33 RS05290
gene id: 465721:ACG33_RS05290
uniprot id: A0A127FA66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

465721:ACG33 RS01600
gene id: 465721:ACG33_RS01600
uniprot id: A0A127F8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

465721:ACG33 RS00550
gene id: 465721:ACG33_RS00550
uniprot id: A0A127F592
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

465721:ACG33 RS12800
gene id: 465721:ACG33_RS12800
uniprot id: A0A127FDZ5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

465721:ACG33 RS15010
gene id: 465721:ACG33_RS15010
uniprot id: A0A127FDC1
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

465721:ACG33 RS12575
gene id: 465721:ACG33_RS12575
uniprot id: A0A127FBY2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

465721:ACG33 RS13610
gene id: 465721:ACG33_RS13610
uniprot id: A0A127FE89
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

465721:ACG33 RS03255
gene id: 465721:ACG33_RS03255
uniprot id: A0A127F6R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

465721:ACG33 RS07980
gene id: 465721:ACG33_RS07980
uniprot id: A0A127FBR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

465721:ACG33 RS07635
gene id: 465721:ACG33_RS07635
uniprot id: A0A127FBP0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

465721:ACG33 RS04405
gene id: 465721:ACG33_RS04405
uniprot id: A0A127F9T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

465721:ACG33 RS09260
gene id: 465721:ACG33_RS09260
uniprot id: A0A127FA36
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

465721:ACG33 RS15220
gene id: 465721:ACG33_RS15220
uniprot id: A0A127FDG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

465721:ACG33 RS02285
gene id: 465721:ACG33_RS02285
uniprot id: A0A127F8M5
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

465721:ACG33 RS08615
gene id: 465721:ACG33_RS08615
uniprot id: A0A127F9R5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

465721:ACG33 RS01110
gene id: 465721:ACG33_RS01110
uniprot id: A0A127F800
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

465721:ACG33 RS12110
gene id: 465721:ACG33_RS12110
uniprot id: A0A127FDU8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

465721:ACG33 RS02005
gene id: 465721:ACG33_RS02005
uniprot id: A0A127F8N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465721:ACG33 RS00555
gene id: 465721:ACG33_RS00555
uniprot id: A0A127F5B8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

465721:ACG33 RS01645
gene id: 465721:ACG33_RS01645
uniprot id: A0A127F887
names: Similarity
messages: Belongs to the UPF0102 family.

465721:ACG33 RS00190
gene id: 465721:ACG33_RS00190
uniprot id: A0A127F7H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

465721:ACG33 RS08015
gene id: 465721:ACG33_RS08015
uniprot id: A0A127FBN3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465721:ACG33 RS06785
gene id: 465721:ACG33_RS06785
uniprot id: A0A127FB25
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

465721:ACG33 RS06150
gene id: 465721:ACG33_RS06150
uniprot id: A0A127F8C5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

465721:ACG33 RS03545
gene id: 465721:ACG33_RS03545
uniprot id: A0A127F6X4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS12170
gene id: 465721:ACG33_RS12170
uniprot id: A0A127FDL7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

465721:ACG33 RS02175
gene id: 465721:ACG33_RS02175
uniprot id: A0A127F687
names: Subcellular Location Annotation
messages: Cell inner membrane

465721:ACG33 RS15140
gene id: 465721:ACG33_RS15140
uniprot id: A0A127FEL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465721:ACG33 RS04100
gene id: 465721:ACG33_RS04100
uniprot id: A0A127F9N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

465721:ACG33 RS09430
gene id: 465721:ACG33_RS09430
uniprot id: A0A127FCG4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

465721:ACG33 RS14180
gene id: 465721:ACG33_RS14180
uniprot id: A0A127FEC5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

465721:ACG33 RS15320
gene id: 465721:ACG33_RS15320
uniprot id: A0A127FDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS15435
gene id: 465721:ACG33_RS15435
uniprot id: A0A127FF25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

465721:ACG33 RS00585
gene id: 465721:ACG33_RS00585
uniprot id: A0A127F5B1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

465721:ACG33 RS06445
gene id: 465721:ACG33_RS06445
uniprot id: A0A127F8J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

465721:ACG33 RS15130
gene id: 465721:ACG33_RS15130
uniprot id: A0A127FEW2
names: Similarity
messages: Belongs to the CobT family.

465721:ACG33 RS05435
gene id: 465721:ACG33_RS05435
uniprot id: A0A127FAD0
names: Similarity
messages: Belongs to the PhoH family.

465721:ACG33 RS08440
gene id: 465721:ACG33_RS08440
uniprot id: A0A127F9N0
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS14430
gene id: 465721:ACG33_RS14430
uniprot id: A0A127FCX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS14755
gene id: 465721:ACG33_RS14755
uniprot id: A0A127FEJ5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

465721:ACG33 RS13245
gene id: 465721:ACG33_RS13245
uniprot id: A0A127FCB5
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

465721:ACG33 RS11320
gene id: 465721:ACG33_RS11320
uniprot id: A0A127FB89
names: Similarity
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.

465721:ACG33 RS09665
gene id: 465721:ACG33_RS09665
uniprot id: A0A127FCQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

465721:ACG33 RS12680
gene id: 465721:ACG33_RS12680
uniprot id: A0A127FBZ5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465721:ACG33 RS14860
gene id: 465721:ACG33_RS14860
uniprot id: A0A127FD83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS03345
gene id: 465721:ACG33_RS03345
uniprot id: A0A127F984
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

465721:ACG33 RS14600
gene id: 465721:ACG33_RS14600
uniprot id: A0A127FD28
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

465721:ACG33 RS13020
gene id: 465721:ACG33_RS13020
uniprot id: A0A127FC80
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

465721:ACG33 RS00665
gene id: 465721:ACG33_RS00665
uniprot id: A0A127F7X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

465721:ACG33 RS04040
gene id: 465721:ACG33_RS04040
uniprot id: A0A127F9K1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

465721:ACG33 RS10565
gene id: 465721:ACG33_RS10565
uniprot id: A0A127FAT6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

465721:ACG33 RS06260
gene id: 465721:ACG33_RS06260
uniprot id: A0A127FAT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

465721:ACG33 RS13905
gene id: 465721:ACG33_RS13905
uniprot id: A0A127FCS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

465721:ACG33 RS05935
gene id: 465721:ACG33_RS05935
uniprot id: A0A127FAM3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

465721:ACG33 RS12220
gene id: 465721:ACG33_RS12220
uniprot id: A0A127FDN1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

465721:ACG33 RS02245
gene id: 465721:ACG33_RS02245
uniprot id: A0A127F6C8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

465721:ACG33 RS10840
gene id: 465721:ACG33_RS10840
uniprot id: A0A127FAY3
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.

465721:ACG33 RS09820
gene id: 465721:ACG33_RS09820
uniprot id: A0A127FCT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS10060
gene id: 465721:ACG33_RS10060
uniprot id: A0A127FAI3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

465721:ACG33 RS04895
gene id: 465721:ACG33_RS04895
uniprot id: A0A127FA35
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

465721:ACG33 RS13325
gene id: 465721:ACG33_RS13325
uniprot id: A0A127F8U7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

465721:ACG33 RS09850
gene id: 465721:ACG33_RS09850
uniprot id: A0A127FCQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

465721:ACG33 RS15365
gene id: 465721:ACG33_RS15365
uniprot id: A0A127FDK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

465721:ACG33 RS12105
gene id: 465721:ACG33_RS12105
uniprot id: A0A127FBM9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

465721:ACG33 RS11165
gene id: 465721:ACG33_RS11165
uniprot id: A0A127FDI7
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS14710
gene id: 465721:ACG33_RS14710
uniprot id: A0A127FD52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

465721:ACG33 RS03740
gene id: 465721:ACG33_RS03740
uniprot id: A0A127F9B8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS05025
gene id: 465721:ACG33_RS05025
uniprot id: A0A127F7S6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465721:ACG33 RS05855
gene id: 465721:ACG33_RS05855
uniprot id: A0A127FAL4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

465721:ACG33 RS05630
gene id: 465721:ACG33_RS05630
uniprot id: A0A127F816
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

465721:ACG33 RS01990
gene id: 465721:ACG33_RS01990
uniprot id: A0A127F627
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS13010
gene id: 465721:ACG33_RS13010
uniprot id: A0A127FE17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

465721:ACG33 RS05400
gene id: 465721:ACG33_RS05400
uniprot id: A0A127F7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

465721:ACG33 RS10960
gene id: 465721:ACG33_RS10960
uniprot id: A0A127FB28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

465721:ACG33 RS11070
gene id: 465721:ACG33_RS11070
uniprot id: A0A127FDD5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

465721:ACG33 RS00785
gene id: 465721:ACG33_RS00785
uniprot id: A0A127F5G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

465721:ACG33 RS01290
gene id: 465721:ACG33_RS01290
uniprot id: A0A127F822
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

465721:ACG33 RS15500
gene id: 465721:ACG33_RS15500
uniprot id: A0A127FEX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

465721:ACG33 RS01815
gene id: 465721:ACG33_RS01815
uniprot id: A0A127F896
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

465721:ACG33 RS08735
gene id: 465721:ACG33_RS08735
uniprot id: A0A127FC62
names: Subcellular Location Annotation
messages: Cytoplasm

465721:ACG33 RS06450
gene id: 465721:ACG33_RS06450
uniprot id: A0A127F8H9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

465721:ACG33 RS05295
gene id: 465721:ACG33_RS05295
uniprot id: A0A127F7V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

465721:ACG33 RS15470
gene id: 465721:ACG33_RS15470
uniprot id: A0A127FDM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

465721:ACG33 RS13040
gene id: 465721:ACG33_RS13040
uniprot id: A0A127FC74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS06225
gene id: 465721:ACG33_RS06225
uniprot id: A0A127FAR6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

465721:ACG33 RS02230
gene id: 465721:ACG33_RS02230
uniprot id: A0A127F683
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465721:ACG33 RS00750
gene id: 465721:ACG33_RS00750
uniprot id: A0A127F5D2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

465721:ACG33 RS13695
gene id: 465721:ACG33_RS13695
uniprot id: A0A127FCK7
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS08585
gene id: 465721:ACG33_RS08585
uniprot id: A0A127F9R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

465721:ACG33 RS05495
gene id: 465721:ACG33_RS05495
uniprot id: A0A127FAA2
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

465721:ACG33 RS06790
gene id: 465721:ACG33_RS06790
uniprot id: A0A127FB78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS14270
gene id: 465721:ACG33_RS14270
uniprot id: A0A127FCY2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

465721:ACG33 RS05220
gene id: 465721:ACG33_RS05220
uniprot id: A0A127F7X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

465721:ACG33 RS04915
gene id: 465721:ACG33_RS04915
uniprot id: A0A127F7Q7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

465721:ACG33 RS11980
gene id: 465721:ACG33_RS11980
uniprot id: A0A127FBK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

465721:ACG33 RS08450
gene id: 465721:ACG33_RS08450
uniprot id: A0A127F9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

465721:ACG33 RS13570
gene id: 465721:ACG33_RS13570
uniprot id: A0A127FE20
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS03585
gene id: 465721:ACG33_RS03585
uniprot id: A0A127F987
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465721:ACG33 RS06210
gene id: 465721:ACG33_RS06210
uniprot id: A0A127FAS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

465721:ACG33 RS09700
gene id: 465721:ACG33_RS09700
uniprot id: A0A127FCP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

465721:ACG33 RS09725
gene id: 465721:ACG33_RS09725
uniprot id: A0A127FCH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

465721:ACG33 RS09415
gene id: 465721:ACG33_RS09415
uniprot id: A0A127FCL0
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

465721:ACG33 RS09450
gene id: 465721:ACG33_RS09450
uniprot id: A0A127FCI6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS02545
gene id: 465721:ACG33_RS02545
uniprot id: A0A127F8S3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

465721:ACG33 RS15490
gene id: 465721:ACG33_RS15490
uniprot id: A0A127FF36
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

465721:ACG33 RS05110
gene id: 465721:ACG33_RS05110
uniprot id: A0A127FA72
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

465721:ACG33 RS08930
gene id: 465721:ACG33_RS08930
uniprot id: A0A127F9X2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

465721:ACG33 RS07650
gene id: 465721:ACG33_RS07650
uniprot id: A0A127F977
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

465721:ACG33 RS00200
gene id: 465721:ACG33_RS00200
uniprot id: A0A127F546
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

465721:ACG33 RS05365
gene id: 465721:ACG33_RS05365
uniprot id: A0A127F7V8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

465721:ACG33 RS14275
gene id: 465721:ACG33_RS14275
uniprot id: A0A127FCW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

465721:ACG33 RS02900
gene id: 465721:ACG33_RS02900
uniprot id: A0A127F6K8
names: Similarity
messages: Belongs to the glutamine synthetase family.

465721:ACG33 RS00005
gene id: 465721:ACG33_RS00005
uniprot id: A0A127F7D4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS02300
gene id: 465721:ACG33_RS02300
uniprot id: A0A127F8M9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

465721:ACG33 RS09495
gene id: 465721:ACG33_RS09495
uniprot id: A0A127FA80
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

465721:ACG33 RS11725
gene id: 465721:ACG33_RS11725
uniprot id: A0A127FBF8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

465721:ACG33 RS02530
gene id: 465721:ACG33_RS02530
uniprot id: A0A127F6A9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

465721:ACG33 RS06015
gene id: 465721:ACG33_RS06015
uniprot id: A0A127FAK7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

465721:ACG33 RS05305
gene id: 465721:ACG33_RS05305
uniprot id: A0A127F7X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

465721:ACG33 RS03005
gene id: 465721:ACG33_RS03005
uniprot id: A0A127F6L5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

465721:ACG33 RS04260
gene id: 465721:ACG33_RS04260
uniprot id: A0A127F7A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

465721:ACG33 RS00950
gene id: 465721:ACG33_RS00950
uniprot id: A0A127F7W9
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

465721:ACG33 RS13015
gene id: 465721:ACG33_RS13015
uniprot id: A0A127FC53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

465721:ACG33 RS09030
gene id: 465721:ACG33_RS09030
uniprot id: A0A127F9Z2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

465721:ACG33 RS10350
gene id: 465721:ACG33_RS10350
uniprot id: A0A127FD01
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS06070
gene id: 465721:ACG33_RS06070
uniprot id: A0A127FAU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

465721:ACG33 RS09135
gene id: 465721:ACG33_RS09135
uniprot id: A0A127FA11
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

465721:ACG33 RS01330
gene id: 465721:ACG33_RS01330
uniprot id: A0A127F5P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

465721:ACG33 RS07470
gene id: 465721:ACG33_RS07470
uniprot id: A0A127F9T9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

465721:ACG33 RS01910
gene id: 465721:ACG33_RS01910
uniprot id: A0A127F8J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

465721:ACG33 RS12865
gene id: 465721:ACG33_RS12865
uniprot id: A0A127FC16
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

465721:ACG33 RS03505
gene id: 465721:ACG33_RS03505
uniprot id: A0A127F9B2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465721:ACG33 RS06610
gene id: 465721:ACG33_RS06610
uniprot id: A0A127F8M3
names: Similarity
messages: Belongs to the YfgM family.

465721:ACG33 RS08655
gene id: 465721:ACG33_RS08655
uniprot id: A0A127F9S0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS04685
gene id: 465721:ACG33_RS04685
uniprot id: A0A127F7I5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

465721:ACG33 RS12040
gene id: 465721:ACG33_RS12040
uniprot id: A0A127FBL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

465721:ACG33 RS08595
gene id: 465721:ACG33_RS08595
uniprot id: A0A127F9R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

465721:ACG33 RS09410
gene id: 465721:ACG33_RS09410
uniprot id: A0A127FA63
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465721:ACG33 RS11295
gene id: 465721:ACG33_RS11295
uniprot id: A0A127FB72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

465721:ACG33 RS14510
gene id: 465721:ACG33_RS14510
uniprot id: A0A127FED1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS05695
gene id: 465721:ACG33_RS05695
uniprot id: A0A127FAI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

465721:ACG33 RS08405
gene id: 465721:ACG33_RS08405
uniprot id: A0A127F9M8
names: Similarity
messages: Belongs to the GSP E family.

465721:ACG33 RS05705
gene id: 465721:ACG33_RS05705
uniprot id: A0A127F849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS04580
gene id: 465721:ACG33_RS04580
uniprot id: A0A127F9S8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

465721:ACG33 RS04120
gene id: 465721:ACG33_RS04120
uniprot id: A0A127F7A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

465721:ACG33 RS00500
gene id: 465721:ACG33_RS00500
uniprot id: A0A127F583
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

465721:ACG33 RS14520
gene id: 465721:ACG33_RS14520
uniprot id: A0A127FD26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

465721:ACG33 RS06360
gene id: 465721:ACG33_RS06360
uniprot id: A0A127FAV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

465721:ACG33 RS01430
gene id: 465721:ACG33_RS01430
uniprot id: A0A127F5S4
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

465721:ACG33 RS13875
gene id: 465721:ACG33_RS13875
uniprot id: A0A127FCN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

465721:ACG33 RS06845
gene id: 465721:ACG33_RS06845
uniprot id: A0A127FB38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

465721:ACG33 RS05270
gene id: 465721:ACG33_RS05270
uniprot id: A0A127F7Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

465721:ACG33 RS01145
gene id: 465721:ACG33_RS01145
uniprot id: A0A127F5L3
names: Subcellular Location Annotation
messages: Mitochondrion

465721:ACG33 RS07175
gene id: 465721:ACG33_RS07175
uniprot id: A0A127F8Y7
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS04165
gene id: 465721:ACG33_RS04165
uniprot id: A0A127F795
names: Similarity
messages: Belongs to the WrbA family.

465721:ACG33 RS09355
gene id: 465721:ACG33_RS09355
uniprot id: A0A127FA50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

465721:ACG33 RS15015
gene id: 465721:ACG33_RS15015
uniprot id: A0A127FDD3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

465721:ACG33 RS03200
gene id: 465721:ACG33_RS03200
uniprot id: A0A127F918
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

465721:ACG33 RS03115
gene id: 465721:ACG33_RS03115
uniprot id: A0A127F6R8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465721:ACG33 RS08020
gene id: 465721:ACG33_RS08020
uniprot id: A0A127F9F3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

465721:ACG33 RS04535
gene id: 465721:ACG33_RS04535
uniprot id: A0A127F7I7
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

465721:ACG33 RS09265
gene id: 465721:ACG33_RS09265
uniprot id: A0A127FCI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

465721:ACG33 RS12795
gene id: 465721:ACG33_RS12795
uniprot id: A0A127FE19
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

465721:ACG33 RS05600
gene id: 465721:ACG33_RS05600
uniprot id: A0A127FAF8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

465721:ACG33 RS04010
gene id: 465721:ACG33_RS04010
uniprot id: A0A127F766
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS12340
gene id: 465721:ACG33_RS12340
uniprot id: A0A127FBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

465721:ACG33 RS00900
gene id: 465721:ACG33_RS00900
uniprot id: A0A127F7V9
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

465721:ACG33 RS00125
gene id: 465721:ACG33_RS00125
uniprot id: A0A127F514
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

465721:ACG33 RS02610
gene id: 465721:ACG33_RS02610
uniprot id: A0A127F6K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

465721:ACG33 RS04725
gene id: 465721:ACG33_RS04725
uniprot id: A0A127FA34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

465721:ACG33 RS13920
gene id: 465721:ACG33_RS13920
uniprot id: A0A127FE97
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS15240
gene id: 465721:ACG33_RS15240
uniprot id: A0A127FEN4
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

465721:ACG33 RS08460
gene id: 465721:ACG33_RS08460
uniprot id: A0A127FC07
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS03440
gene id: 465721:ACG33_RS03440
uniprot id: A0A127F6U1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS08890
gene id: 465721:ACG33_RS08890
uniprot id: A0A127F9V8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

465721:ACG33 RS06850
gene id: 465721:ACG33_RS06850
uniprot id: A0A127FB06
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

465721:ACG33 RS14295
gene id: 465721:ACG33_RS14295
uniprot id: A0A127FCV9
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

465721:ACG33 RS12715
gene id: 465721:ACG33_RS12715
uniprot id: A0A127FBZ9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465721:ACG33 RS10930
gene id: 465721:ACG33_RS10930
uniprot id: A0A127FDB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS04350
gene id: 465721:ACG33_RS04350
uniprot id: A0A127F9R8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS16165
gene id: 465721:ACG33_RS16165
uniprot id: A0A127FAP7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS02460
gene id: 465721:ACG33_RS02460
uniprot id: A0A127F8Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

465721:ACG33 RS00110
gene id: 465721:ACG33_RS00110
uniprot id: A0A127F7L9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

465721:ACG33 RS07220
gene id: 465721:ACG33_RS07220
uniprot id: A0A127FBG2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS01170
gene id: 465721:ACG33_RS01170
uniprot id: A0A127F5N5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

465721:ACG33 RS03090
gene id: 465721:ACG33_RS03090
uniprot id: A0A127F971
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS00805
gene id: 465721:ACG33_RS00805
uniprot id: A0A127F5G7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465721:ACG33 RS02570
gene id: 465721:ACG33_RS02570
uniprot id: A0A127F8Z6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

465721:ACG33 RS05595
gene id: 465721:ACG33_RS05595
uniprot id: A0A127FAJ9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

465721:ACG33 RS02410
gene id: 465721:ACG33_RS02410
uniprot id: A0A127F8W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

465721:ACG33 RS01445
gene id: 465721:ACG33_RS01445
uniprot id: A0A127F8B3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

465721:ACG33 RS05960
gene id: 465721:ACG33_RS05960
uniprot id: A0A127FAN2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

465721:ACG33 RS09365
gene id: 465721:ACG33_RS09365
uniprot id: A0A127FCK3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

465721:ACG33 RS15355
gene id: 465721:ACG33_RS15355
uniprot id: A0A127FDL5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

465721:ACG33 RS09860
gene id: 465721:ACG33_RS09860
uniprot id: A0A127FAF1
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS10970
gene id: 465721:ACG33_RS10970
uniprot id: A0A127FDC3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

465721:ACG33 RS02875
gene id: 465721:ACG33_RS02875
uniprot id: A0A127F8Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

465721:ACG33 RS11150
gene id: 465721:ACG33_RS11150
uniprot id: A0A127FDE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS10470
gene id: 465721:ACG33_RS10470
uniprot id: A0A127FAR7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

465721:ACG33 RS11045
gene id: 465721:ACG33_RS11045
uniprot id: A0A127FB19
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

465721:ACG33 RS05500
gene id: 465721:ACG33_RS05500
uniprot id: A0A127F7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

465721:ACG33 RS04280
gene id: 465721:ACG33_RS04280
uniprot id: A0A127F7B6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS04870
gene id: 465721:ACG33_RS04870
uniprot id: A0A127F7Q9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

465721:ACG33 RS00620
gene id: 465721:ACG33_RS00620
uniprot id: A0A127F7V4
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

465721:ACG33 RS05785
gene id: 465721:ACG33_RS05785
uniprot id: A0A127F890
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

465721:ACG33 RS02215
gene id: 465721:ACG33_RS02215
uniprot id: A0A127F8H6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

465721:ACG33 RS06590
gene id: 465721:ACG33_RS06590
uniprot id: A0A127FAZ0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

465721:ACG33 RS07015
gene id: 465721:ACG33_RS07015
uniprot id: A0A127FB74
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS05955
gene id: 465721:ACG33_RS05955
uniprot id: A0A127FAS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

465721:ACG33 RS10515
gene id: 465721:ACG33_RS10515
uniprot id: A0A127FAS7
names: Similarity
messages: Belongs to the histone deacetylase family.

465721:ACG33 RS06430
gene id: 465721:ACG33_RS06430
uniprot id: A0A127FB14
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465721:ACG33 RS07205
gene id: 465721:ACG33_RS07205
uniprot id: A0A127F8Z5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

465721:ACG33 RS09290
gene id: 465721:ACG33_RS09290
uniprot id: A0A127FA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

465721:ACG33 RS10870
gene id: 465721:ACG33_RS10870
uniprot id: A0A127FDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

465721:ACG33 RS09830
gene id: 465721:ACG33_RS09830
uniprot id: A0A127FCP1
names: Similarity
messages: Belongs to the MobA/MobL family.

465721:ACG33 RS12235
gene id: 465721:ACG33_RS12235
uniprot id: A0A127FBR4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

465721:ACG33 RS00095
gene id: 465721:ACG33_RS00095
uniprot id: A0A127F4Z7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

465721:ACG33 RS02140
gene id: 465721:ACG33_RS02140
uniprot id: A0A127F653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS15480
gene id: 465721:ACG33_RS15480
uniprot id: A0A127FDL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

465721:ACG33 RS01730
gene id: 465721:ACG33_RS01730
uniprot id: A0A127F5X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

465721:ACG33 RS03810
gene id: 465721:ACG33_RS03810
uniprot id: A0A127F724
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

465721:ACG33 RS10985
gene id: 465721:ACG33_RS10985
uniprot id: A0A127FB21
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

465721:ACG33 RS01505
gene id: 465721:ACG33_RS01505
uniprot id: A0A127F8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

465721:ACG33 RS11260
gene id: 465721:ACG33_RS11260
uniprot id: A0A127FB81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

465721:ACG33 RS10365
gene id: 465721:ACG33_RS10365
uniprot id: A0A127FAP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

465721:ACG33 RS03735
gene id: 465721:ACG33_RS03735
uniprot id: A0A127F9G1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS13160
gene id: 465721:ACG33_RS13160
uniprot id: A0A127FE38
names: Similarity
messages: Belongs to the LOG family.

465721:ACG33 RS05455
gene id: 465721:ACG33_RS05455
uniprot id: A0A127F808
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS02190
gene id: 465721:ACG33_RS02190
uniprot id: A0A127F663
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS04435
gene id: 465721:ACG33_RS04435
uniprot id: A0A127F7G7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465721:ACG33 RS11050
gene id: 465721:ACG33_RS11050
uniprot id: A0A127FDD2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

465721:ACG33 RS04560
gene id: 465721:ACG33_RS04560
uniprot id: A0A127F9V6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

465721:ACG33 RS07575
gene id: 465721:ACG33_RS07575
uniprot id: A0A127F973
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS00100
gene id: 465721:ACG33_RS00100
uniprot id: A0A127F524
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

465721:ACG33 RS06480
gene id: 465721:ACG33_RS06480
uniprot id: A0A127FB20
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465721:ACG33 RS03025
gene id: 465721:ACG33_RS03025
uniprot id: A0A127F6L2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

465721:ACG33 RS06470
gene id: 465721:ACG33_RS06470
uniprot id: A0A127F8K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS05135
gene id: 465721:ACG33_RS05135
uniprot id: A0A127FA62
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

465721:ACG33 RS02335
gene id: 465721:ACG33_RS02335
uniprot id: A0A127F8N5
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS09780
gene id: 465721:ACG33_RS09780
uniprot id: A0A127FCM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465721:ACG33 RS15000
gene id: 465721:ACG33_RS15000
uniprot id: A0A127FDC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

465721:ACG33 RS11420
gene id: 465721:ACG33_RS11420
uniprot id: A0A127FBA9
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS11820
gene id: 465721:ACG33_RS11820
uniprot id: A0A127FBI3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS05125
gene id: 465721:ACG33_RS05125
uniprot id: A0A127F7R7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

465721:ACG33 RS11275
gene id: 465721:ACG33_RS11275
uniprot id: A0A127FDH9
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

465721:ACG33 RS04030
gene id: 465721:ACG33_RS04030
uniprot id: A0A127F7A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

465721:ACG33 RS13820
gene id: 465721:ACG33_RS13820
uniprot id: A0A127FE90
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465721:ACG33 RS12730
gene id: 465721:ACG33_RS12730
uniprot id: A0A127FC04
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

465721:ACG33 RS15275
gene id: 465721:ACG33_RS15275
uniprot id: A0A127FDJ6
names: Similarity
messages: Belongs to the RutC family.

465721:ACG33 RS04555
gene id: 465721:ACG33_RS04555
uniprot id: A0A127F7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

465721:ACG33 RS08635
gene id: 465721:ACG33_RS08635
uniprot id: A0A127FC18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

465721:ACG33 RS16545
gene id: 465721:ACG33_RS16545
uniprot id: A0A127FCK4
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

465721:ACG33 RS10825
gene id: 465721:ACG33_RS10825
uniprot id: A0A127FD96
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

465721:ACG33 RS15380
gene id: 465721:ACG33_RS15380
uniprot id: A0A127FDL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS08630
gene id: 465721:ACG33_RS08630
uniprot id: A0A127FC44
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

465721:ACG33 RS12940
gene id: 465721:ACG33_RS12940
uniprot id: A0A127FC37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

465721:ACG33 RS06175
gene id: 465721:ACG33_RS06175
uniprot id: A0A127FAQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

465721:ACG33 RS00945
gene id: 465721:ACG33_RS00945
uniprot id: A0A127F5H1
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

465721:ACG33 RS16715
gene id: 465721:ACG33_RS16715
uniprot id: A0A127FB44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465721:ACG33 RS02980
gene id: 465721:ACG33_RS02980
uniprot id: A0A127F902
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

465721:ACG33 RS06950
gene id: 465721:ACG33_RS06950
uniprot id: A0A127FBB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

465721:ACG33 RS04140
gene id: 465721:ACG33_RS04140
uniprot id: A0A127F9M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

465721:ACG33 RS14900
gene id: 465721:ACG33_RS14900
uniprot id: A0A127FDA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

465721:ACG33 RS03185
gene id: 465721:ACG33_RS03185
uniprot id: A0A127F943
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

465721:ACG33 RS02565
gene id: 465721:ACG33_RS02565
uniprot id: A0A127F8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

465721:ACG33 RS01680
gene id: 465721:ACG33_RS01680
uniprot id: A0A127F5W9
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

465721:ACG33 RS13850
gene id: 465721:ACG33_RS13850
uniprot id: A0A127FE98
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

465721:ACG33 RS14620
gene id: 465721:ACG33_RS14620
uniprot id: A0A127FEI0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465721:ACG33 RS04200
gene id: 465721:ACG33_RS04200
uniprot id: A0A127F9Q6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS08925
gene id: 465721:ACG33_RS08925
uniprot id: A0A127F9X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

465721:ACG33 RS06425
gene id: 465721:ACG33_RS06425
uniprot id: A0A127FAV5
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

465721:ACG33 RS02040
gene id: 465721:ACG33_RS02040
uniprot id: A0A127F636
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS05120
gene id: 465721:ACG33_RS05120
uniprot id: A0A127F7S5
names: Similarity
messages: Belongs to the peptidase S49 family.

465721:ACG33 RS05420
gene id: 465721:ACG33_RS05420
uniprot id: A0A127F818
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

465721:ACG33 RS08130
gene id: 465721:ACG33_RS08130
uniprot id: A0A127F9H0
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

465721:ACG33 RS06170
gene id: 465721:ACG33_RS06170
uniprot id: A0A127F8F2
names: Function
names: Subcellular Location Annotation
messages: Nuclear serine protease which mediates apoptosis.
messages: Nucleus

465721:ACG33 RS06120
gene id: 465721:ACG33_RS06120
uniprot id: A0A127F8E1
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

465721:ACG33 RS14110
gene id: 465721:ACG33_RS14110
uniprot id: A0A127FCV1
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS06855
gene id: 465721:ACG33_RS06855
uniprot id: A0A127F8S2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

465721:ACG33 RS00215
gene id: 465721:ACG33_RS00215
uniprot id: A0A127F7L0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS12350
gene id: 465721:ACG33_RS12350
uniprot id: A0A127FDU9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

465721:ACG33 RS13865
gene id: 465721:ACG33_RS13865
uniprot id: A0A127FCN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

465721:ACG33 RS05625
gene id: 465721:ACG33_RS05625
uniprot id: A0A127FAF6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

465721:ACG33 RS00075
gene id: 465721:ACG33_RS00075
uniprot id: A0A127F503
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465721:ACG33 RS13675
gene id: 465721:ACG33_RS13675
uniprot id: A0A127FE87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

465721:ACG33 RS08570
gene id: 465721:ACG33_RS08570
uniprot id: A0A127FC33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS03510
gene id: 465721:ACG33_RS03510
uniprot id: A0A127F6V7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

465721:ACG33 RS09425
gene id: 465721:ACG33_RS09425
uniprot id: A0A127FCD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS10005
gene id: 465721:ACG33_RS10005
uniprot id: A0A127FAH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

465721:ACG33 RS02750
gene id: 465721:ACG33_RS02750
uniprot id: A0A127F6H5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

465721:ACG33 RS08090
gene id: 465721:ACG33_RS08090
uniprot id: A0A127F9F9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS10255
gene id: 465721:ACG33_RS10255
uniprot id: A0A127FCZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS11950
gene id: 465721:ACG33_RS11950
uniprot id: A0A127FBK5
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS09235
gene id: 465721:ACG33_RS09235
uniprot id: A0A127FA27
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

465721:ACG33 RS14065
gene id: 465721:ACG33_RS14065
uniprot id: A0A127FCR1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

465721:ACG33 RS14815
gene id: 465721:ACG33_RS14815
uniprot id: A0A127FD84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

465721:ACG33 RS03460
gene id: 465721:ACG33_RS03460
uniprot id: A0A127F6U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS06960
gene id: 465721:ACG33_RS06960
uniprot id: A0A127FB26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

465721:ACG33 RS01400
gene id: 465721:ACG33_RS01400
uniprot id: A0A127F8A3
names: Similarity
messages: Belongs to the YggT family.

465721:ACG33 RS09360
gene id: 465721:ACG33_RS09360
uniprot id: A0A127FA54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

465721:ACG33 RS05555
gene id: 465721:ACG33_RS05555
uniprot id: A0A127F806
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

465721:ACG33 RS15055
gene id: 465721:ACG33_RS15055
uniprot id: A0A127FEQ7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

465721:ACG33 RS01490
gene id: 465721:ACG33_RS01490
uniprot id: A0A127F858
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

465721:ACG33 RS03665
gene id: 465721:ACG33_RS03665
uniprot id: A0A127F739
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.

465721:ACG33 RS05320
gene id: 465721:ACG33_RS05320
uniprot id: A0A127F802
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

465721:ACG33 RS00030
gene id: 465721:ACG33_RS00030
uniprot id: A0A127F4Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

465721:ACG33 RS10455
gene id: 465721:ACG33_RS10455
uniprot id: A0A127FD20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

465721:ACG33 RS05425
gene id: 465721:ACG33_RS05425
uniprot id: A0A127FAB8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

465721:ACG33 RS04530
gene id: 465721:ACG33_RS04530
uniprot id: A0A127F7G4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

465721:ACG33 RS09050
gene id: 465721:ACG33_RS09050
uniprot id: A0A127FCE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

465721:ACG33 RS03050
gene id: 465721:ACG33_RS03050
uniprot id: A0A127F8Y8
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

465721:ACG33 RS02085
gene id: 465721:ACG33_RS02085
uniprot id: A0A127F8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

465721:ACG33 RS06530
gene id: 465721:ACG33_RS06530
uniprot id: A0A127FAX6
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS05300
gene id: 465721:ACG33_RS05300
uniprot id: A0A127F7V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

465721:ACG33 RS08520
gene id: 465721:ACG33_RS08520
uniprot id: A0A127FBZ4
names: Similarity
messages: Belongs to the threonine synthase family.

465721:ACG33 RS07395
gene id: 465721:ACG33_RS07395
uniprot id: A0A127F917
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

465721:ACG33 RS08360
gene id: 465721:ACG33_RS08360
uniprot id: A0A127FBZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465721:ACG33 RS02360
gene id: 465721:ACG33_RS02360
uniprot id: A0A127F8T0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

465721:ACG33 RS05265
gene id: 465721:ACG33_RS05265
uniprot id: A0A127F7T9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

465721:ACG33 RS14835
gene id: 465721:ACG33_RS14835
uniprot id: A0A127FEM1
names: Similarity
messages: Belongs to the LOG family.

465721:ACG33 RS14300
gene id: 465721:ACG33_RS14300
uniprot id: A0A127FEF7
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

465721:ACG33 RS10030
gene id: 465721:ACG33_RS10030
uniprot id: A0A127FCW0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

465721:ACG33 RS08745
gene id: 465721:ACG33_RS08745
uniprot id: A0A127FC28
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

465721:ACG33 RS09180
gene id: 465721:ACG33_RS09180
uniprot id: A0A127FA17
names: Similarity
messages: Belongs to the Dps family.

465721:ACG33 RS02205
gene id: 465721:ACG33_RS02205
uniprot id: A0A127F8S1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

465721:ACG33 RS15475
gene id: 465721:ACG33_RS15475
uniprot id: A0A127FEX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

465721:ACG33 RS13270
gene id: 465721:ACG33_RS13270
uniprot id: A0A127FE43
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS10510
gene id: 465721:ACG33_RS10510
uniprot id: A0A127FAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS14160
gene id: 465721:ACG33_RS14160
uniprot id: A0A127FEC7
names: Similarity
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

465721:ACG33 RS07660
gene id: 465721:ACG33_RS07660
uniprot id: A0A127F986
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

465721:ACG33 RS05340
gene id: 465721:ACG33_RS05340
uniprot id: A0A127FA77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

465721:ACG33 RS08940
gene id: 465721:ACG33_RS08940
uniprot id: A0A127F9W9
names: Similarity
messages: Belongs to the GSP C family.

465721:ACG33 RS12580
gene id: 465721:ACG33_RS12580
uniprot id: A0A127FDZ2
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

465721:ACG33 RS07115
gene id: 465721:ACG33_RS07115
uniprot id: A0A127FB91
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

465721:ACG33 RS04425
gene id: 465721:ACG33_RS04425
uniprot id: A0A127F7D1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465721:ACG33 RS12030
gene id: 465721:ACG33_RS12030
uniprot id: A0A127FBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS08385
gene id: 465721:ACG33_RS08385
uniprot id: A0A127F9M5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465721:ACG33 RS06655
gene id: 465721:ACG33_RS06655
uniprot id: A0A127F8M0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

465721:ACG33 RS05895
gene id: 465721:ACG33_RS05895
uniprot id: A0A127FAL0
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

465721:ACG33 RS02865
gene id: 465721:ACG33_RS02865
uniprot id: A0A127F6I1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

465721:ACG33 RS08210
gene id: 465721:ACG33_RS08210
uniprot id: A0A127FBV4
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

465721:ACG33 RS13910
gene id: 465721:ACG33_RS13910
uniprot id: A0A127FCN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

465721:ACG33 RS05810
gene id: 465721:ACG33_RS05810
uniprot id: A0A127F866
names: Similarity
messages: Belongs to the type III secretion exporter family.

465721:ACG33 RS06465
gene id: 465721:ACG33_RS06465
uniprot id: A0A127F8I9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465721:ACG33 RS15340
gene id: 465721:ACG33_RS15340
uniprot id: A0A127FEQ6
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS14615
gene id: 465721:ACG33_RS14615
uniprot id: A0A127FEE1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

465721:ACG33 RS10755
gene id: 465721:ACG33_RS10755
uniprot id: A0A127FAX0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS12035
gene id: 465721:ACG33_RS12035
uniprot id: A0A127FBM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

465721:ACG33 RS09485
gene id: 465721:ACG33_RS09485
uniprot id: A0A127FA78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

465721:ACG33 RS15150
gene id: 465721:ACG33_RS15150
uniprot id: A0A127FDH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

465721:ACG33 RS04440
gene id: 465721:ACG33_RS04440
uniprot id: A0A127F9T4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465721:ACG33 RS11960
gene id: 465721:ACG33_RS11960
uniprot id: A0A127FDT5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

465721:ACG33 RS07950
gene id: 465721:ACG33_RS07950
uniprot id: A0A127FBT3
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

465721:ACG33 RS15035
gene id: 465721:ACG33_RS15035
uniprot id: A0A127FEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

465721:ACG33 RS02935
gene id: 465721:ACG33_RS02935
uniprot id: A0A127F921
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

465721:ACG33 RS04850
gene id: 465721:ACG33_RS04850
uniprot id: A0A127F7P3
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

465721:ACG33 RS07750
gene id: 465721:ACG33_RS07750
uniprot id: A0A127FBH5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

465721:ACG33 RS04255
gene id: 465721:ACG33_RS04255
uniprot id: A0A127F9M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

465721:ACG33 RS06145
gene id: 465721:ACG33_RS06145
uniprot id: A0A127F8C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

465721:ACG33 RS06245
gene id: 465721:ACG33_RS06245
uniprot id: A0A127F8E7
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

465721:ACG33 RS11925
gene id: 465721:ACG33_RS11925
uniprot id: A0A127FDP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS12695
gene id: 465721:ACG33_RS12695
uniprot id: A0A127FDU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465721:ACG33 RS07690
gene id: 465721:ACG33_RS07690
uniprot id: A0A127FBQ0
names: Similarity
messages: Belongs to the GSP N family.

465721:ACG33 RS07890
gene id: 465721:ACG33_RS07890
uniprot id: A0A127FBT0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

465721:ACG33 RS09115
gene id: 465721:ACG33_RS09115
uniprot id: A0A127FC84
names: Similarity
messages: Belongs to the catalase family.

465721:ACG33 RS07100
gene id: 465721:ACG33_RS07100
uniprot id: A0A127F8X1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

465721:ACG33 RS10610
gene id: 465721:ACG33_RS10610
uniprot id: A0A127FD57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465721:ACG33 RS08910
gene id: 465721:ACG33_RS08910
uniprot id: A0A127FC48
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

465721:ACG33 RS09675
gene id: 465721:ACG33_RS09675
uniprot id: A0A127FCG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

465721:ACG33 RS12875
gene id: 465721:ACG33_RS12875
uniprot id: A0A127FC35
names: Subcellular Location Annotation
messages: Cell inner membrane

465721:ACG33 RS13950
gene id: 465721:ACG33_RS13950
uniprot id: A0A127FEA8
names: Similarity
messages: Belongs to the peptidase M16 family.

465721:ACG33 RS11280
gene id: 465721:ACG33_RS11280
uniprot id: A0A127FD95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

465721:ACG33 RS14925
gene id: 465721:ACG33_RS14925
uniprot id: A0A127FEL7
names: Similarity
messages: Belongs to the UPF0234 family.

465721:ACG33 RS00165
gene id: 465721:ACG33_RS00165
uniprot id: A0A127F7K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

465721:ACG33 RS16635
gene id: 465721:ACG33_RS16635
uniprot id: A0A127F5K0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

465721:ACG33 RS06760
gene id: 465721:ACG33_RS06760
uniprot id: A0A127F8P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

465721:ACG33 RS10325
gene id: 465721:ACG33_RS10325
uniprot id: A0A127FAN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465721:ACG33 RS10360
gene id: 465721:ACG33_RS10360
uniprot id: A0A127FAN9
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

465721:ACG33 RS05095
gene id: 465721:ACG33_RS05095
uniprot id: A0A127F7V2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

465721:ACG33 RS00590
gene id: 465721:ACG33_RS00590
uniprot id: A0A127F5A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

465721:ACG33 RS02920
gene id: 465721:ACG33_RS02920
uniprot id: A0A127F6Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465721:ACG33 RS10530
gene id: 465721:ACG33_RS10530
uniprot id: A0A127FAT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

465721:ACG33 RS00530
gene id: 465721:ACG33_RS00530
uniprot id: A0A127F598
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

465721:ACG33 RS14825
gene id: 465721:ACG33_RS14825
uniprot id: A0A127FEK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS14630
gene id: 465721:ACG33_RS14630
uniprot id: A0A127FD33
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

465721:ACG33 RS01040
gene id: 465721:ACG33_RS01040
uniprot id: A0A127F5L0
names: Similarity
messages: Belongs to the GST superfamily.

465721:ACG33 RS11195
gene id: 465721:ACG33_RS11195
uniprot id: A0A127FB52
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

465721:ACG33 RS02585
gene id: 465721:ACG33_RS02585
uniprot id: A0A127F6D0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465721:ACG33 RS03340
gene id: 465721:ACG33_RS03340
uniprot id: A0A127F6V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

465721:ACG33 RS07075
gene id: 465721:ACG33_RS07075
uniprot id: A0A127F8W8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

465721:ACG33 RS07390
gene id: 465721:ACG33_RS07390
uniprot id: A0A127FBA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS11300
gene id: 465721:ACG33_RS11300
uniprot id: A0A127FB75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

465721:ACG33 RS01590
gene id: 465721:ACG33_RS01590
uniprot id: A0A127F5W1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

465721:ACG33 RS10385
gene id: 465721:ACG33_RS10385
uniprot id: A0A127FAP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

465721:ACG33 RS12075
gene id: 465721:ACG33_RS12075
uniprot id: A0A127FDQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

465721:ACG33 RS05355
gene id: 465721:ACG33_RS05355
uniprot id: A0A127F7Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

465721:ACG33 RS15370
gene id: 465721:ACG33_RS15370
uniprot id: A0A127FEV6
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

465721:ACG33 RS05200
gene id: 465721:ACG33_RS05200
uniprot id: A0A127F7T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

465721:ACG33 RS06010
gene id: 465721:ACG33_RS06010
uniprot id: A0A127FAP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

465721:ACG33 RS04240
gene id: 465721:ACG33_RS04240
uniprot id: A0A127F9P6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

465721:ACG33 RS05715
gene id: 465721:ACG33_RS05715
uniprot id: A0A127F862
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

465721:ACG33 RS05205
gene id: 465721:ACG33_RS05205
uniprot id: A0A127F7V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

465721:ACG33 RS10915
gene id: 465721:ACG33_RS10915
uniprot id: A0A127FDC2
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS10460
gene id: 465721:ACG33_RS10460
uniprot id: A0A127FAR2
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

465721:ACG33 RS03600
gene id: 465721:ACG33_RS03600
uniprot id: A0A127F707
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

465721:ACG33 RS04070
gene id: 465721:ACG33_RS04070
uniprot id: A0A127F797
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS13885
gene id: 465721:ACG33_RS13885
uniprot id: A0A127FEB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

465721:ACG33 RS15135
gene id: 465721:ACG33_RS15135
uniprot id: A0A127FEQ2
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

465721:ACG33 RS13965
gene id: 465721:ACG33_RS13965
uniprot id: A0A127FCP7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

465721:ACG33 RS13860
gene id: 465721:ACG33_RS13860
uniprot id: A0A127FCM2
names: Similarity
messages: Belongs to the UPF0758 family.

465721:ACG33 RS06410
gene id: 465721:ACG33_RS06410
uniprot id: A0A127FAW6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

465721:ACG33 RS14090
gene id: 465721:ACG33_RS14090
uniprot id: A0A127FED8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

465721:ACG33 RS10520
gene id: 465721:ACG33_RS10520
uniprot id: A0A127FAS5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

465721:ACG33 RS05720
gene id: 465721:ACG33_RS05720
uniprot id: A0A127FAI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

465721:ACG33 RS03160
gene id: 465721:ACG33_RS03160
uniprot id: A0A127F6Q9
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

465721:ACG33 RS06605
gene id: 465721:ACG33_RS06605
uniprot id: A0A127F8L4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS05170
gene id: 465721:ACG33_RS05170
uniprot id: A0A127FA68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

465721:ACG33 RS00135
gene id: 465721:ACG33_RS00135
uniprot id: A0A127F509
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

465721:ACG33 RS04015
gene id: 465721:ACG33_RS04015
uniprot id: A0A127F783
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS08115
gene id: 465721:ACG33_RS08115
uniprot id: A0A127FBU5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

465721:ACG33 RS03855
gene id: 465721:ACG33_RS03855
uniprot id: A0A127F719
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS15450
gene id: 465721:ACG33_RS15450
uniprot id: A0A127FEY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

465721:ACG33 RS05385
gene id: 465721:ACG33_RS05385
uniprot id: A0A127FAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

465721:ACG33 RS02910
gene id: 465721:ACG33_RS02910
uniprot id: A0A127F8Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

465721:ACG33 RS04855
gene id: 465721:ACG33_RS04855
uniprot id: A0A127FA14
names: Similarity
messages: Belongs to the phosphohexose mutase family.

465721:ACG33 RS15395
gene id: 465721:ACG33_RS15395
uniprot id: A0A127FER1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

465721:ACG33 RS01760
gene id: 465721:ACG33_RS01760
uniprot id: A0A127F8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

465721:ACG33 RS04365
gene id: 465721:ACG33_RS04365
uniprot id: A0A127F9U1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

465721:ACG33 RS07400
gene id: 465721:ACG33_RS07400
uniprot id: A0A127F940
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS05325
gene id: 465721:ACG33_RS05325
uniprot id: A0A127FA99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

465721:ACG33 RS06905
gene id: 465721:ACG33_RS06905
uniprot id: A0A127FB17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465721:ACG33 RS05210
gene id: 465721:ACG33_RS05210
uniprot id: A0A127FA76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

465721:ACG33 RS06745
gene id: 465721:ACG33_RS06745
uniprot id: A0A127FAZ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465721:ACG33 RS13590
gene id: 465721:ACG33_RS13590
uniprot id: A0A127FCI8
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

465721:ACG33 RS08525
gene id: 465721:ACG33_RS08525
uniprot id: A0A127FC00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

465721:ACG33 RS08105
gene id: 465721:ACG33_RS08105
uniprot id: A0A127F9G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

465721:ACG33 RS04660
gene id: 465721:ACG33_RS04660
uniprot id: A0A127F9X6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

465721:ACG33 RS12855
gene id: 465721:ACG33_RS12855
uniprot id: A0A127FDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

465721:ACG33 RS15225
gene id: 465721:ACG33_RS15225
uniprot id: A0A127FDI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

465721:ACG33 RS10580
gene id: 465721:ACG33_RS10580
uniprot id: A0A127FD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS05850
gene id: 465721:ACG33_RS05850
uniprot id: A0A127FAR1
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

465721:ACG33 RS07105
gene id: 465721:ACG33_RS07105
uniprot id: A0A127FB88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465721:ACG33 RS06805
gene id: 465721:ACG33_RS06805
uniprot id: A0A127F8R2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

465721:ACG33 RS09730
gene id: 465721:ACG33_RS09730
uniprot id: A0A127FCL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

465721:ACG33 RS11270
gene id: 465721:ACG33_RS11270
uniprot id: A0A127FDK7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

465721:ACG33 RS14930
gene id: 465721:ACG33_RS14930
uniprot id: A0A127FEH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465721:ACG33 RS15505
gene id: 465721:ACG33_RS15505
uniprot id: A0A127FES4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

465721:ACG33 RS07535
gene id: 465721:ACG33_RS07535
uniprot id: A0A127FBH2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

465721:ACG33 RS10760
gene id: 465721:ACG33_RS10760
uniprot id: A0A127FD81
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS13000
gene id: 465721:ACG33_RS13000
uniprot id: A0A127FE21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

465721:ACG33 RS13095
gene id: 465721:ACG33_RS13095
uniprot id: A0A127FC93
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465721:ACG33 RS03350
gene id: 465721:ACG33_RS03350
uniprot id: A0A127F6S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS15100
gene id: 465721:ACG33_RS15100
uniprot id: A0A127FDG5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

465721:ACG33 RS05440
gene id: 465721:ACG33_RS05440
uniprot id: A0A127FA92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

465721:ACG33 RS09625
gene id: 465721:ACG33_RS09625
uniprot id: A0A127FCG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

465721:ACG33 RS11155
gene id: 465721:ACG33_RS11155
uniprot id: A0A127FB60
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

465721:ACG33 RS11145
gene id: 465721:ACG33_RS11145
uniprot id: A0A127FB42
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

465721:ACG33 RS00920
gene id: 465721:ACG33_RS00920
uniprot id: A0A127F817
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

465721:ACG33 RS02595
gene id: 465721:ACG33_RS02595
uniprot id: A0A127F6G7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

465721:ACG33 RS01825
gene id: 465721:ACG33_RS01825
uniprot id: A0A127F605
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

465721:ACG33 RS14500
gene id: 465721:ACG33_RS14500
uniprot id: A0A127FEJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

465721:ACG33 RS05405
gene id: 465721:ACG33_RS05405
uniprot id: A0A127F7Z3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

465721:ACG33 RS09375
gene id: 465721:ACG33_RS09375
uniprot id: A0A127FCD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

465721:ACG33 RS07230
gene id: 465721:ACG33_RS07230
uniprot id: A0A127FB76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

465721:ACG33 RS06930
gene id: 465721:ACG33_RS06930
uniprot id: A0A127F8S9
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS15385
gene id: 465721:ACG33_RS15385
uniprot id: A0A127FF16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

465721:ACG33 RS00130
gene id: 465721:ACG33_RS00130
uniprot id: A0A127F505
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

465721:ACG33 RS06140
gene id: 465721:ACG33_RS06140
uniprot id: A0A127FAM6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

465721:ACG33 RS04690
gene id: 465721:ACG33_RS04690
uniprot id: A0A127F7J2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

465721:ACG33 RS03955
gene id: 465721:ACG33_RS03955
uniprot id: A0A127F741
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS01920
gene id: 465721:ACG33_RS01920
uniprot id: A0A127F614
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

465721:ACG33 RS14035
gene id: 465721:ACG33_RS14035
uniprot id: A0A127FCS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

465721:ACG33 RS01865
gene id: 465721:ACG33_RS01865
uniprot id: A0A127F8A5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

465721:ACG33 RS11160
gene id: 465721:ACG33_RS11160
uniprot id: A0A127FB63
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

465721:ACG33 RS05660
gene id: 465721:ACG33_RS05660
uniprot id: A0A127F840
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

465721:ACG33 RS06370
gene id: 465721:ACG33_RS06370
uniprot id: A0A127F8J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

465721:ACG33 RS02010
gene id: 465721:ACG33_RS02010
uniprot id: A0A127F8L3
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

465721:ACG33 RS06585
gene id: 465721:ACG33_RS06585
uniprot id: A0A127FB39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

465721:ACG33 RS09945
gene id: 465721:ACG33_RS09945
uniprot id: A0A127FAG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

465721:ACG33 RS05250
gene id: 465721:ACG33_RS05250
uniprot id: A0A127F7U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

465721:ACG33 RS13855
gene id: 465721:ACG33_RS13855
uniprot id: A0A127FCN4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS05310
gene id: 465721:ACG33_RS05310
uniprot id: A0A127FA97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

465721:ACG33 RS08395
gene id: 465721:ACG33_RS08395
uniprot id: A0A127FBX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

465721:ACG33 RS08420
gene id: 465721:ACG33_RS08420
uniprot id: A0A127FBX7
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

465721:ACG33 RS00345
gene id: 465721:ACG33_RS00345
uniprot id: A0A127F548
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS05360
gene id: 465721:ACG33_RS05360
uniprot id: A0A127FAA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

465721:ACG33 RS08490
gene id: 465721:ACG33_RS08490
uniprot id: A0A127F9N7
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

465721:ACG33 RS02810
gene id: 465721:ACG33_RS02810
uniprot id: A0A127F8X3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465721:ACG33 RS12570
gene id: 465721:ACG33_RS12570
uniprot id: A0A127FBX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

465721:ACG33 RS15040
gene id: 465721:ACG33_RS15040
uniprot id: A0A127FDE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS06305
gene id: 465721:ACG33_RS06305
uniprot id: A0A127F8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

465721:ACG33 RS06885
gene id: 465721:ACG33_RS06885
uniprot id: A0A127F8T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465721:ACG33 RS06700
gene id: 465721:ACG33_RS06700
uniprot id: A0A127F8P0
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

465721:ACG33 RS00730
gene id: 465721:ACG33_RS00730
uniprot id: A0A127F5D3
names: Similarity
messages: Belongs to the P(II) protein family.

465721:ACG33 RS09270
gene id: 465721:ACG33_RS09270
uniprot id: A0A127FCF9
names: Similarity
messages: Belongs to the UPF0434 family.

465721:ACG33 RS08030
gene id: 465721:ACG33_RS08030
uniprot id: A0A127F9E7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

465721:ACG33 RS02525
gene id: 465721:ACG33_RS02525
uniprot id: A0A127F8N8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

465721:ACG33 RS03535
gene id: 465721:ACG33_RS03535
uniprot id: A0A127F979
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS11410
gene id: 465721:ACG33_RS11410
uniprot id: A0A127FDI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS03935
gene id: 465721:ACG33_RS03935
uniprot id: A0A127F9H6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS15050
gene id: 465721:ACG33_RS15050
uniprot id: A0A127FDD4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

465721:ACG33 RS11290
gene id: 465721:ACG33_RS11290
uniprot id: A0A127FB80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

465721:ACG33 RS08045
gene id: 465721:ACG33_RS08045
uniprot id: A0A127FBR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

465721:ACG33 RS03145
gene id: 465721:ACG33_RS03145
uniprot id: A0A127F946
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

465721:ACG33 RS12215
gene id: 465721:ACG33_RS12215
uniprot id: A0A127FDV4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

465721:ACG33 RS06920
gene id: 465721:ACG33_RS06920
uniprot id: A0A127F8T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465721:ACG33 RS02930
gene id: 465721:ACG33_RS02930
uniprot id: A0A127F941
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

465721:ACG33 RS11765
gene id: 465721:ACG33_RS11765
uniprot id: A0A127FDM0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

465721:ACG33 RS08100
gene id: 465721:ACG33_RS08100
uniprot id: A0A127F9F5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

465721:ACG33 RS00875
gene id: 465721:ACG33_RS00875
uniprot id: A0A127F7Z9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

465721:ACG33 RS04065
gene id: 465721:ACG33_RS04065
uniprot id: A0A127F777
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

465721:ACG33 RS16940
gene id: 465721:ACG33_RS16940
uniprot id: A0A127F864
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

465721:ACG33 RS13705
gene id: 465721:ACG33_RS13705
uniprot id: A0A127FCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS01945
gene id: 465721:ACG33_RS01945
uniprot id: A0A127F638
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

465721:ACG33 RS13555
gene id: 465721:ACG33_RS13555
uniprot id: A0A127FCH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

465721:ACG33 RS09610
gene id: 465721:ACG33_RS09610
uniprot id: A0A127FAA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

465721:ACG33 RS04630
gene id: 465721:ACG33_RS04630
uniprot id: A0A127F7H4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

465721:ACG33 RS02195
gene id: 465721:ACG33_RS02195
uniprot id: A0A127F6A4
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS12710
gene id: 465721:ACG33_RS12710
uniprot id: A0A127FC32
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS09390
gene id: 465721:ACG33_RS09390
uniprot id: A0A127FA57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

465721:ACG33 RS04845
gene id: 465721:ACG33_RS04845
uniprot id: A0A127F7M5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

465721:ACG33 RS00365
gene id: 465721:ACG33_RS00365
uniprot id: A0A127F7P6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS05105
gene id: 465721:ACG33_RS05105
uniprot id: A0A127FAB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

465721:ACG33 RS08650
gene id: 465721:ACG33_RS08650
uniprot id: A0A127F9S4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS05970
gene id: 465721:ACG33_RS05970
uniprot id: A0A127F895
names: Similarity
messages: Belongs to the peptidase U62 family.

465721:ACG33 RS01725
gene id: 465721:ACG33_RS01725
uniprot id: A0A127F5Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

465721:ACG33 RS07665
gene id: 465721:ACG33_RS07665
uniprot id: A0A127F978
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

465721:ACG33 RS13530
gene id: 465721:ACG33_RS13530
uniprot id: A0A127FCG6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465721:ACG33 RS08540
gene id: 465721:ACG33_RS08540
uniprot id: A0A127F9P8
names: Similarity
messages: Belongs to the pirin family.

465721:ACG33 RS06415
gene id: 465721:ACG33_RS06415
uniprot id: A0A127F8I0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

465721:ACG33 RS14490
gene id: 465721:ACG33_RS14490
uniprot id: A0A127FCZ5
names: Similarity
messages: Belongs to the citrate synthase family.

465721:ACG33 RS06935
gene id: 465721:ACG33_RS06935
uniprot id: A0A127F8U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

465721:ACG33 RS01255
gene id: 465721:ACG33_RS01255
uniprot id: A0A127F5N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS11250
gene id: 465721:ACG33_RS11250
uniprot id: A0A127FDG6
names: Cofactor
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

465721:ACG33 RS01515
gene id: 465721:ACG33_RS01515
uniprot id: A0A127F5T7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

465721:ACG33 RS05330
gene id: 465721:ACG33_RS05330
uniprot id: A0A127FAF3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

465721:ACG33 RS11620
gene id: 465721:ACG33_RS11620
uniprot id: A0A127FBD5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

465721:ACG33 RS05235
gene id: 465721:ACG33_RS05235
uniprot id: A0A127FA68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

465721:ACG33 RS14515
gene id: 465721:ACG33_RS14515
uniprot id: A0A127FEG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

465721:ACG33 RS10025
gene id: 465721:ACG33_RS10025
uniprot id: A0A127FAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

465721:ACG33 RS05790
gene id: 465721:ACG33_RS05790
uniprot id: A0A127FAJ3
names: Similarity
messages: Belongs to the MotB family.

465721:ACG33 RS13135
gene id: 465721:ACG33_RS13135
uniprot id: A0A127FC73
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS06385
gene id: 465721:ACG33_RS06385
uniprot id: A0A127FAV6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

465721:ACG33 RS10345
gene id: 465721:ACG33_RS10345
uniprot id: A0A127FCT6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS13205
gene id: 465721:ACG33_RS13205
uniprot id: A0A127FE61
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465721:ACG33 RS06290
gene id: 465721:ACG33_RS06290
uniprot id: A0A127FAQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

465721:ACG33 RS08610
gene id: 465721:ACG33_RS08610
uniprot id: A0A127F9Q5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

465721:ACG33 RS05245
gene id: 465721:ACG33_RS05245
uniprot id: A0A127F7U1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

465721:ACG33 RS05240
gene id: 465721:ACG33_RS05240
uniprot id: A0A127FA55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

465721:ACG33 RS13060
gene id: 465721:ACG33_RS13060
uniprot id: A0A127FDY0
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

465721:ACG33 RS09765
gene id: 465721:ACG33_RS09765
uniprot id: A0A127FCR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

465721:ACG33 RS15280
gene id: 465721:ACG33_RS15280
uniprot id: A0A127FEZ8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

465721:ACG33 RS05580
gene id: 465721:ACG33_RS05580
uniprot id: A0A127F803
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

465721:ACG33 RS03630
gene id: 465721:ACG33_RS03630
uniprot id: A0A127F9E1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

465721:ACG33 RS07025
gene id: 465721:ACG33_RS07025
uniprot id: A0A127F8V6
names: Similarity
messages: Belongs to the BolA/IbaG family.

465721:ACG33 RS09810
gene id: 465721:ACG33_RS09810
uniprot id: A0A127FAE4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465721:ACG33 RS09615
gene id: 465721:ACG33_RS09615
uniprot id: A0A127FCQ1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

465721:ACG33 RS04125
gene id: 465721:ACG33_RS04125
uniprot id: A0A127F9M7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS06365
gene id: 465721:ACG33_RS06365
uniprot id: A0A127F8H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

465721:ACG33 RS07200
gene id: 465721:ACG33_RS07200
uniprot id: A0A127F8X6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

465721:ACG33 RS05770
gene id: 465721:ACG33_RS05770
uniprot id: A0A127F873
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

465721:ACG33 RS03295
gene id: 465721:ACG33_RS03295
uniprot id: A0A127F976
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS06155
gene id: 465721:ACG33_RS06155
uniprot id: A0A127F8D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

465721:ACG33 RS12050
gene id: 465721:ACG33_RS12050
uniprot id: A0A127FBM6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

465721:ACG33 RS08010
gene id: 465721:ACG33_RS08010
uniprot id: A0A127FBQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

465721:ACG33 RS06810
gene id: 465721:ACG33_RS06810
uniprot id: A0A127F8Q1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

465721:ACG33 RS03015
gene id: 465721:ACG33_RS03015
uniprot id: A0A127F6P7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

465721:ACG33 RS14595
gene id: 465721:ACG33_RS14595
uniprot id: A0A127FD24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

465721:ACG33 RS11210
gene id: 465721:ACG33_RS11210
uniprot id: A0A127FB73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

465721:ACG33 RS00350
gene id: 465721:ACG33_RS00350
uniprot id: A0A127F576
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465721:ACG33 RS02480
gene id: 465721:ACG33_RS02480
uniprot id: A0A127F6A5
names: Similarity
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.

465721:ACG33 RS04375
gene id: 465721:ACG33_RS04375
uniprot id: A0A127F7C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

465721:ACG33 RS12355
gene id: 465721:ACG33_RS12355
uniprot id: A0A127FBT6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

465721:ACG33 RS06840
gene id: 465721:ACG33_RS06840
uniprot id: A0A127FB87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

465721:ACG33 RS00905
gene id: 465721:ACG33_RS00905
uniprot id: A0A127F5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

465721:ACG33 RS12455
gene id: 465721:ACG33_RS12455
uniprot id: A0A127FBY5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

465721:ACG33 RS06800
gene id: 465721:ACG33_RS06800
uniprot id: A0A127FAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

465721:ACG33 RS09995
gene id: 465721:ACG33_RS09995
uniprot id: A0A127FCT1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

465721:ACG33 RS09240
gene id: 465721:ACG33_RS09240
uniprot id: A0A127FA31
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

465721:ACG33 RS02555
gene id: 465721:ACG33_RS02555
uniprot id: A0A127F6A2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

465721:ACG33 RS02435
gene id: 465721:ACG33_RS02435
uniprot id: A0A127F6C7
names: Similarity
messages: Belongs to the PhzF family.

465721:ACG33 RS01785
gene id: 465721:ACG33_RS01785
uniprot id: A0A127F8C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

465721:ACG33 RS11225
gene id: 465721:ACG33_RS11225
uniprot id: A0A127FD87
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

465721:ACG33 RS05260
gene id: 465721:ACG33_RS05260
uniprot id: A0A127FA88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

465721:ACG33 RS11675
gene id: 465721:ACG33_RS11675
uniprot id: A0A127FBE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

465721:ACG33 RS06830
gene id: 465721:ACG33_RS06830
uniprot id: A0A127F8S4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

465721:ACG33 RS02200
gene id: 465721:ACG33_RS02200
uniprot id: A0A127F8K7
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS10440
gene id: 465721:ACG33_RS10440
uniprot id: A0A127FD32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

465721:ACG33 RS07235
gene id: 465721:ACG33_RS07235
uniprot id: A0A127F904
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

465721:ACG33 RS10890
gene id: 465721:ACG33_RS10890
uniprot id: A0A127FAZ8
names: Similarity
messages: Belongs to the ModE family.

465721:ACG33 RS08955
gene id: 465721:ACG33_RS08955
uniprot id: A0A127FCA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

465721:ACG33 RS03110
gene id: 465721:ACG33_RS03110
uniprot id: A0A127F6P8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

465721:ACG33 RS05865
gene id: 465721:ACG33_RS05865
uniprot id: A0A127F877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

465721:ACG33 RS02670
gene id: 465721:ACG33_RS02670
uniprot id: A0A127F8U7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

465721:ACG33 RS04575
gene id: 465721:ACG33_RS04575
uniprot id: A0A127F9X9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

465721:ACG33 RS07695
gene id: 465721:ACG33_RS07695
uniprot id: A0A127FBK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS09525
gene id: 465721:ACG33_RS09525
uniprot id: A0A127FCF2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS14750
gene id: 465721:ACG33_RS14750
uniprot id: A0A127FD66
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

465721:ACG33 RS05350
gene id: 465721:ACG33_RS05350
uniprot id: A0A127F7W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

465721:ACG33 RS13145
gene id: 465721:ACG33_RS13145
uniprot id: A0A127FCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

465721:ACG33 RS03970
gene id: 465721:ACG33_RS03970
uniprot id: A0A127F9J9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

465721:ACG33 RS06580
gene id: 465721:ACG33_RS06580
uniprot id: A0A127FAY5
names: Similarity
messages: Belongs to the HesB/IscA family.

465721:ACG33 RS10410
gene id: 465721:ACG33_RS10410
uniprot id: A0A127FAQ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

465721:ACG33 RS01765
gene id: 465721:ACG33_RS01765
uniprot id: A0A127F886
names: Similarity
messages: Belongs to the Nudix hydrolase family.

465721:ACG33 RS09865
gene id: 465721:ACG33_RS09865
uniprot id: A0A127FCU0
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS09460
gene id: 465721:ACG33_RS09460
uniprot id: A0A127FA73
names: Similarity
messages: Belongs to the RecJ family.

465721:ACG33 RS02125
gene id: 465721:ACG33_RS02125
uniprot id: A0A127F669
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS09530
gene id: 465721:ACG33_RS09530
uniprot id: A0A127FCI1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

465721:ACG33 RS00935
gene id: 465721:ACG33_RS00935
uniprot id: A0A127F5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

465721:ACG33 RS14190
gene id: 465721:ACG33_RS14190
uniprot id: A0A127FCU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

465721:ACG33 RS07715
gene id: 465721:ACG33_RS07715
uniprot id: A0A127F990
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

465721:ACG33 RS11170
gene id: 465721:ACG33_RS11170
uniprot id: A0A127FDF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS03215
gene id: 465721:ACG33_RS03215
uniprot id: A0A127F6T7
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

465721:ACG33 RS09645
gene id: 465721:ACG33_RS09645
uniprot id: A0A127FAA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

465721:ACG33 RS07005
gene id: 465721:ACG33_RS07005
uniprot id: A0A127FB67
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

465721:ACG33 RS03880
gene id: 465721:ACG33_RS03880
uniprot id: A0A127F781
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS06565
gene id: 465721:ACG33_RS06565
uniprot id: A0A127FAZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS13840
gene id: 465721:ACG33_RS13840
uniprot id: A0A127FE96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

465721:ACG33 RS07985
gene id: 465721:ACG33_RS07985
uniprot id: A0A127F9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

465721:ACG33 RS13585
gene id: 465721:ACG33_RS13585
uniprot id: A0A127FCH2
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

465721:ACG33 RS10865
gene id: 465721:ACG33_RS10865
uniprot id: A0A127FDA2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

465721:ACG33 RS01925
gene id: 465721:ACG33_RS01925
uniprot id: A0A127F628
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

465721:ACG33 RS02485
gene id: 465721:ACG33_RS02485
uniprot id: A0A127F6D3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

465721:ACG33 RS13975
gene id: 465721:ACG33_RS13975
uniprot id: A0A127FCP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

465721:ACG33 RS01300
gene id: 465721:ACG33_RS01300
uniprot id: A0A127F879
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

465721:ACG33 RS04800
gene id: 465721:ACG33_RS04800
uniprot id: A0A127F7N0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

465721:ACG33 RS04080
gene id: 465721:ACG33_RS04080
uniprot id: A0A127F778
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

465721:ACG33 RS03475
gene id: 465721:ACG33_RS03475
uniprot id: A0A127F9D6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465721:ACG33 RS06955
gene id: 465721:ACG33_RS06955
uniprot id: A0A127FB59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

465721:ACG33 RS14265
gene id: 465721:ACG33_RS14265
uniprot id: A0A127FED9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

465721:ACG33 RS05750
gene id: 465721:ACG33_RS05750
uniprot id: A0A127FAJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

465721:ACG33 RS01975
gene id: 465721:ACG33_RS01975
uniprot id: A0A127F640
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

465721:ACG33 RS12135
gene id: 465721:ACG33_RS12135
uniprot id: A0A127FBP2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

465721:ACG33 RS06110
gene id: 465721:ACG33_RS06110
uniprot id: A0A127FAQ3
names: Similarity
messages: Belongs to the peptidase M24B family.

465721:ACG33 RS06775
gene id: 465721:ACG33_RS06775
uniprot id: A0A127F8P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

465721:ACG33 RS01735
gene id: 465721:ACG33_RS01735
uniprot id: A0A127F8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

465721:ACG33 RS11040
gene id: 465721:ACG33_RS11040
uniprot id: A0A127FB24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the PduL family.
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

465721:ACG33 RS05185
gene id: 465721:ACG33_RS05185
uniprot id: A0A127FA81
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

465721:ACG33 RS02225
gene id: 465721:ACG33_RS02225
uniprot id: A0A127F692
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS10595
gene id: 465721:ACG33_RS10595
uniprot id: A0A127FD49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

465721:ACG33 RS01415
gene id: 465721:ACG33_RS01415
uniprot id: A0A127F5S5
names: Similarity
messages: Belongs to the GSP E family.

465721:ACG33 RS11790
gene id: 465721:ACG33_RS11790
uniprot id: A0A127FBH6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

465721:ACG33 RS03265
gene id: 465721:ACG33_RS03265
uniprot id: A0A127F6U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

465721:ACG33 RS00740
gene id: 465721:ACG33_RS00740
uniprot id: A0A127F5D4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

465721:ACG33 RS15210
gene id: 465721:ACG33_RS15210
uniprot id: A0A127FDH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

465721:ACG33 RS03300
gene id: 465721:ACG33_RS03300
uniprot id: A0A127F932
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS04340
gene id: 465721:ACG33_RS04340
uniprot id: A0A127F7C6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

465721:ACG33 RS04820
gene id: 465721:ACG33_RS04820
uniprot id: A0A127FA09
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

465721:ACG33 RS03280
gene id: 465721:ACG33_RS03280
uniprot id: A0A127F6X8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

465721:ACG33 RS04990
gene id: 465721:ACG33_RS04990
uniprot id: A0A127F7S9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

465721:ACG33 RS08945
gene id: 465721:ACG33_RS08945
uniprot id: A0A127F9X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

465721:ACG33 RS14435
gene id: 465721:ACG33_RS14435
uniprot id: A0A127FEF0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

465721:ACG33 RS12790
gene id: 465721:ACG33_RS12790
uniprot id: A0A127FC11
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

465721:ACG33 RS14830
gene id: 465721:ACG33_RS14830
uniprot id: A0A127FEG2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

465721:ACG33 RS09555
gene id: 465721:ACG33_RS09555
uniprot id: A0A127FA94
names: Similarity
messages: Belongs to the SUI1 family.

465721:ACG33 RS00845
gene id: 465721:ACG33_RS00845
uniprot id: A0A127F5F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

465721:ACG33 RS04905
gene id: 465721:ACG33_RS04905
uniprot id: A0A127F7M3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

465721:ACG33 RS08935
gene id: 465721:ACG33_RS08935
uniprot id: A0A127FC97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

465721:ACG33 RS05985
gene id: 465721:ACG33_RS05985
uniprot id: A0A127FAN5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

465721:ACG33 RS06095
gene id: 465721:ACG33_RS06095
uniprot id: A0A127F8B2
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

465721:ACG33 RS10735
gene id: 465721:ACG33_RS10735
uniprot id: A0A127FAW8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

465721:ACG33 RS15515
gene id: 465721:ACG33_RS15515
uniprot id: A0A127FDP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

465721:ACG33 RS04055
gene id: 465721:ACG33_RS04055
uniprot id: A0A127F9H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

465721:ACG33 RS06620
gene id: 465721:ACG33_RS06620
uniprot id: A0A127F8L9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

465721:ACG33 RS04020
gene id: 465721:ACG33_RS04020
uniprot id: A0A127F9K7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465721:ACG33 RS08765
gene id: 465721:ACG33_RS08765
uniprot id: A0A127F9T9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

465721:ACG33 RS11200
gene id: 465721:ACG33_RS11200
uniprot id: A0A127FDF2
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

465721:ACG33 RS12140
gene id: 465721:ACG33_RS12140
uniprot id: A0A127FBN7
names: Similarity
messages: Belongs to the GARS family.

465721:ACG33 RS01700
gene id: 465721:ACG33_RS01700
uniprot id: A0A127F898
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

465721:ACG33 RS01625
gene id: 465721:ACG33_RS01625
uniprot id: A0A127F5V2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

465721:ACG33 RS10205
gene id: 465721:ACG33_RS10205
uniprot id: A0A127FAM1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

465721:ACG33 RS07010
gene id: 465721:ACG33_RS07010
uniprot id: A0A127FBC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

465721:ACG33 RS03445
gene id: 465721:ACG33_RS03445
uniprot id: A0A127F6V6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS06770
gene id: 465721:ACG33_RS06770
uniprot id: A0A127FB33
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

465721:ACG33 RS12155
gene id: 465721:ACG33_RS12155
uniprot id: A0A127FBN9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

465721:ACG33 RS14285
gene id: 465721:ACG33_RS14285
uniprot id: A0A127FED5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

465721:ACG33 RS10380
gene id: 465721:ACG33_RS10380
uniprot id: A0A127FAP6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465721:ACG33 RS06115
gene id: 465721:ACG33_RS06115
uniprot id: A0A127F8B4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

465721:ACG33 RS08050
gene id: 465721:ACG33_RS08050
uniprot id: A0A127F9E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

465721:ACG33 RS08700
gene id: 465721:ACG33_RS08700
uniprot id: A0A127F9S9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

465721:ACG33 RS08095
gene id: 465721:ACG33_RS08095
uniprot id: A0A127FBS7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

465721:ACG33 RS09620
gene id: 465721:ACG33_RS09620
uniprot id: A0A127FCP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

465721:ACG33 RS05640
gene id: 465721:ACG33_RS05640
uniprot id: A0A127FAF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

465721:ACG33 RS00765
gene id: 465721:ACG33_RS00765
uniprot id: A0A127F7Z1
names: Similarity
messages: Belongs to the peptidase S9C family.

465721:ACG33 RS09385
gene id: 465721:ACG33_RS09385
uniprot id: A0A127FA59
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465721:ACG33 RS13870
gene id: 465721:ACG33_RS13870
uniprot id: A0A127FE94
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

465721:ACG33 RS00515
gene id: 465721:ACG33_RS00515
uniprot id: A0A127F7U7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

465721:ACG33 RS09300
gene id: 465721:ACG33_RS09300
uniprot id: A0A127FCG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

465721:ACG33 RS14590
gene id: 465721:ACG33_RS14590
uniprot id: A0A127FEG5
names: Subcellular Location Annotation
messages: Membrane

465721:ACG33 RS13650
gene id: 465721:ACG33_RS13650
uniprot id: A0A127FE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

465721:ACG33 RS02885
gene id: 465721:ACG33_RS02885
uniprot id: A0A127F919
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

465721:ACG33 RS06265
gene id: 465721:ACG33_RS06265
uniprot id: A0A127F8F0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

465721:ACG33 RS01120
gene id: 465721:ACG33_RS01120
uniprot id: A0A127F5M5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

465721:ACG33 RS01770
gene id: 465721:ACG33_RS01770
uniprot id: A0A127F5Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

465721:ACG33 RS00480
gene id: 465721:ACG33_RS00480
uniprot id: A0A127F588
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS07110
gene id: 465721:ACG33_RS07110
uniprot id: A0A127FBE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

465721:ACG33 RS13470
gene id: 465721:ACG33_RS13470
uniprot id: A0A127FE15
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

465721:ACG33 RS10795
gene id: 465721:ACG33_RS10795
uniprot id: A0A127FD85
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

465721:ACG33 RS06300
gene id: 465721:ACG33_RS06300
uniprot id: A0A127F8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

465721:ACG33 RS02785
gene id: 465721:ACG33_RS02785
uniprot id: A0A127F906
names: Similarity
messages: Belongs to the thioredoxin family.

465721:ACG33 RS12720
gene id: 465721:ACG33_RS12720
uniprot id: A0A127FDY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

465721:ACG33 RS15190
gene id: 465721:ACG33_RS15190
uniprot id: A0A127FEM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

465721:ACG33 RS12460
gene id: 465721:ACG33_RS12460
uniprot id: A0A127FBW0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

465721:ACG33 RS14530
gene id: 465721:ACG33_RS14530
uniprot id: A0A127FD02
names: Similarity
messages: Belongs to the YicC/YloC family.

465721:ACG33 RS04135
gene id: 465721:ACG33_RS04135
uniprot id: A0A127F7D0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

465721:ACG33 RS15180
gene id: 465721:ACG33_RS15180
uniprot id: A0A127FEX2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

465721:ACG33 RS15250
gene id: 465721:ACG33_RS15250
uniprot id: A0A127FDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

465721:ACG33 RS05335
gene id: 465721:ACG33_RS05335
uniprot id: A0A127FAA8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

465721:ACG33 RS15205
gene id: 465721:ACG33_RS15205
uniprot id: A0A127FDI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

465721:ACG33 RS14185
gene id: 465721:ACG33_RS14185
uniprot id: A0A127FCT9
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

465721:ACG33 RS10550
gene id: 465721:ACG33_RS10550
uniprot id: A0A127FCX6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

465721:ACG33 RS12185
gene id: 465721:ACG33_RS12185
uniprot id: A0A127FBQ3
names: Similarity
messages: Belongs to the thioredoxin family.

465721:ACG33 RS05190
gene id: 465721:ACG33_RS05190
uniprot id: A0A127FA43
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

465721:ACG33 RS14280
gene id: 465721:ACG33_RS14280
uniprot id: A0A127FCU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

465721:ACG33 RS11825
gene id: 465721:ACG33_RS11825
uniprot id: A0A127FBH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465721:ACG33 RS10995
gene id: 465721:ACG33_RS10995
uniprot id: A0A127FB13
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

465721:ACG33 RS00520
gene id: 465721:ACG33_RS00520
uniprot id: A0A127F7T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

465721:ACG33 RS13100
gene id: 465721:ACG33_RS13100
uniprot id: A0A127FC78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465721:ACG33 RS07480
gene id: 465721:ACG33_RS07480
uniprot id: A0A127FBL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

465721:ACG33 RS12655
gene id: 465721:ACG33_RS12655
uniprot id: A0A127FC22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.