455488:A2CP1 RS11375
gene id: 455488:A2CP1_RS11375
uniprot id: B8JA82
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

455488:A2CP1 RS11865
gene id: 455488:A2CP1_RS11865
uniprot id: B8JB72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

455488:A2CP1 RS12650
gene id: 455488:A2CP1_RS12650
uniprot id: B8JCA9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.

455488:A2CP1 RS13085
gene id: 455488:A2CP1_RS13085
uniprot id: B8JD85
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

455488:A2CP1 RS11855
gene id: 455488:A2CP1_RS11855
uniprot id: B8JB70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

455488:A2CP1 RS09755
gene id: 455488:A2CP1_RS09755
uniprot id: B8J795
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

455488:A2CP1 RS08080
gene id: 455488:A2CP1_RS08080
uniprot id: B8J598
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS21235
gene id: 455488:A2CP1_RS21235
uniprot id: B8JAN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

455488:A2CP1 RS08790
gene id: 455488:A2CP1_RS08790
uniprot id: B8J6B2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS19085
gene id: 455488:A2CP1_RS19085
uniprot id: B8J7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

455488:A2CP1 RS15170
gene id: 455488:A2CP1_RS15170
uniprot id: B8JFG7
names: Similarity
messages: Belongs to the GSP E family.

455488:A2CP1 RS19830
gene id: 455488:A2CP1_RS19830
uniprot id: B8J8H2
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS12025
gene id: 455488:A2CP1_RS12025
uniprot id: B8JB99
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

455488:A2CP1 RS03670
gene id: 455488:A2CP1_RS03670
uniprot id: B8JD64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

455488:A2CP1 RS06850
gene id: 455488:A2CP1_RS06850
uniprot id: B8JGN6
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS10300
gene id: 455488:A2CP1_RS10300
uniprot id: B8J893
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

455488:A2CP1 RS11655
gene id: 455488:A2CP1_RS11655
uniprot id: B8JAD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

455488:A2CP1 RS05710
gene id: 455488:A2CP1_RS05710
uniprot id: B8JFQ1
names: Similarity
messages: Belongs to the TrbI/VirB10 family.

455488:A2CP1 RS11505
gene id: 455488:A2CP1_RS11505
uniprot id: B8JAA8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

455488:A2CP1 RS11295
gene id: 455488:A2CP1_RS11295
uniprot id: B8JA66
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

455488:A2CP1 RS22395
gene id: 455488:A2CP1_RS22395
uniprot id: B8JCQ3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

455488:A2CP1 RS12880
gene id: 455488:A2CP1_RS12880
uniprot id: B8JCF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

455488:A2CP1 RS11810
gene id: 455488:A2CP1_RS11810
uniprot id: B8JB61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

455488:A2CP1 RS09775
gene id: 455488:A2CP1_RS09775
uniprot id: B8J799
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

455488:A2CP1 RS12735
gene id: 455488:A2CP1_RS12735
uniprot id: B8JCC6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

455488:A2CP1 RS21365
gene id: 455488:A2CP1_RS21365
uniprot id: B8JAR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

455488:A2CP1 RS18155
gene id: 455488:A2CP1_RS18155
uniprot id: B8J638
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

455488:A2CP1 RS11940
gene id: 455488:A2CP1_RS11940
uniprot id: B8JB82
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

455488:A2CP1 RS21230
gene id: 455488:A2CP1_RS21230
uniprot id: B8JAN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

455488:A2CP1 RS07985
gene id: 455488:A2CP1_RS07985
uniprot id: B8J579
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS15415
gene id: 455488:A2CP1_RS15415
uniprot id: B8JFL7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

455488:A2CP1 RS12940
gene id: 455488:A2CP1_RS12940
uniprot id: B8JCG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

455488:A2CP1 RS00730
gene id: 455488:A2CP1_RS00730
uniprot id: B8J812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

455488:A2CP1 RS14055
gene id: 455488:A2CP1_RS14055
uniprot id: B8JE59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

455488:A2CP1 RS22845
gene id: 455488:A2CP1_RS22845
uniprot id: B8J7E6
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS19605
gene id: 455488:A2CP1_RS19605
uniprot id: B8J7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

455488:A2CP1 RS07805
gene id: 455488:A2CP1_RS07805
uniprot id: B8J543
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS17875
gene id: 455488:A2CP1_RS17875
uniprot id: B8J5Y0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

455488:A2CP1 RS12640
gene id: 455488:A2CP1_RS12640
uniprot id: B8JCA7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

455488:A2CP1 RS14520
gene id: 455488:A2CP1_RS14520
uniprot id: B8JES0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

455488:A2CP1 RS22215
gene id: 455488:A2CP1_RS22215
uniprot id: B8JCL2
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS22340
gene id: 455488:A2CP1_RS22340
uniprot id: B8JCP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

455488:A2CP1 RS07280
gene id: 455488:A2CP1_RS07280
uniprot id: B8JH91
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

455488:A2CP1 RS02045
gene id: 455488:A2CP1_RS02045
uniprot id: B8JAV9
names: Similarity
messages: Belongs to the LEA type 2 family.

455488:A2CP1 RS21830
gene id: 455488:A2CP1_RS21830
uniprot id: B8JBP6
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00750
gene id: 455488:A2CP1_RS00750
uniprot id: B8J8R0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

455488:A2CP1 RS12605
gene id: 455488:A2CP1_RS12605
uniprot id: B8JCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

455488:A2CP1 RS16230
gene id: 455488:A2CP1_RS16230
uniprot id: B8JGR9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

455488:A2CP1 RS07215
gene id: 455488:A2CP1_RS07215
uniprot id: B8JH79
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

455488:A2CP1 RS04930
gene id: 455488:A2CP1_RS04930
uniprot id: B8JEL5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

455488:A2CP1 RS01450
gene id: 455488:A2CP1_RS01450
uniprot id: B8J9U8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

455488:A2CP1 RS06945
gene id: 455488:A2CP1_RS06945
uniprot id: B8JH24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS18760
gene id: 455488:A2CP1_RS18760
uniprot id: B8J6S7
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

455488:A2CP1 RS10590
gene id: 455488:A2CP1_RS10590
uniprot id: B8J943
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

455488:A2CP1 RS02185
gene id: 455488:A2CP1_RS02185
uniprot id: B8JAY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

455488:A2CP1 RS02785
gene id: 455488:A2CP1_RS02785
uniprot id: B8JBZ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS22350
gene id: 455488:A2CP1_RS22350
uniprot id: B8JCP3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

455488:A2CP1 RS03750
gene id: 455488:A2CP1_RS03750
uniprot id: B8JDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

455488:A2CP1 RS16715
gene id: 455488:A2CP1_RS16715
uniprot id: B8JHE3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS12315
gene id: 455488:A2CP1_RS12315
uniprot id: B8JBF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS13955
gene id: 455488:A2CP1_RS13955
uniprot id: B8JE44
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS06880
gene id: 455488:A2CP1_RS06880
uniprot id: B8JH11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

455488:A2CP1 RS16840
gene id: 455488:A2CP1_RS16840
uniprot id: B8JHG7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

455488:A2CP1 RS21695
gene id: 455488:A2CP1_RS21695
uniprot id: B8JBL9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS03055
gene id: 455488:A2CP1_RS03055
uniprot id: B8JC48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

455488:A2CP1 RS17330
gene id: 455488:A2CP1_RS17330
uniprot id: B8J5B0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

455488:A2CP1 RS10265
gene id: 455488:A2CP1_RS10265
uniprot id: B8J886
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

455488:A2CP1 RS21785
gene id: 455488:A2CP1_RS21785
uniprot id: B8JBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

455488:A2CP1 RS19395
gene id: 455488:A2CP1_RS19395
uniprot id: B8J7J3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS04750
gene id: 455488:A2CP1_RS04750
uniprot id: B8JEI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

455488:A2CP1 RS01155
gene id: 455488:A2CP1_RS01155
uniprot id: B8J8Z4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

455488:A2CP1 RS10195
gene id: 455488:A2CP1_RS10195
uniprot id: B8J872
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

455488:A2CP1 RS05915
gene id: 455488:A2CP1_RS05915
uniprot id: B8JFU1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

455488:A2CP1 RS11305
gene id: 455488:A2CP1_RS11305
uniprot id: B8JA68
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

455488:A2CP1 RS07535
gene id: 455488:A2CP1_RS07535
uniprot id: B8J4Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

455488:A2CP1 RS18865
gene id: 455488:A2CP1_RS18865
uniprot id: B8J6U8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

455488:A2CP1 RS19255
gene id: 455488:A2CP1_RS19255
uniprot id: B8J7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

455488:A2CP1 RS13155
gene id: 455488:A2CP1_RS13155
uniprot id: B8JD99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

455488:A2CP1 RS07860
gene id: 455488:A2CP1_RS07860
uniprot id: B8J554
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

455488:A2CP1 RS07675
gene id: 455488:A2CP1_RS07675
uniprot id: B8J517
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS16525
gene id: 455488:A2CP1_RS16525
uniprot id: B8JGX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

455488:A2CP1 RS19690
gene id: 455488:A2CP1_RS19690
uniprot id: B8J8E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

455488:A2CP1 RS13840
gene id: 455488:A2CP1_RS13840
uniprot id: B8JE20
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

455488:A2CP1 RS11665
gene id: 455488:A2CP1_RS11665
uniprot id: B8JAE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

455488:A2CP1 RS10290
gene id: 455488:A2CP1_RS10290
uniprot id: B8J891
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

455488:A2CP1 RS22535
gene id: 455488:A2CP1_RS22535
uniprot id: B8JCT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

455488:A2CP1 RS11130
gene id: 455488:A2CP1_RS11130
uniprot id: B8J9E6
names: Similarity
messages: Belongs to the threonine synthase family.

455488:A2CP1 RS06900
gene id: 455488:A2CP1_RS06900
uniprot id: B8JH15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS08060
gene id: 455488:A2CP1_RS08060
uniprot id: B8J594
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

455488:A2CP1 RS14025
gene id: 455488:A2CP1_RS14025
uniprot id: B8JE58
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS13485
gene id: 455488:A2CP1_RS13485
uniprot id: B8JDG5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

455488:A2CP1 RS05025
gene id: 455488:A2CP1_RS05025
uniprot id: B8JF03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

455488:A2CP1 RS05680
gene id: 455488:A2CP1_RS05680
uniprot id: B8JFP4
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

455488:A2CP1 RS18165
gene id: 455488:A2CP1_RS18165
uniprot id: B8J641
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

455488:A2CP1 RS21585
gene id: 455488:A2CP1_RS21585
uniprot id: B8JBJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

455488:A2CP1 RS22000
gene id: 455488:A2CP1_RS22000
uniprot id: B8JBT1
names: Similarity
messages: Belongs to the ArsC family.

455488:A2CP1 RS13995
gene id: 455488:A2CP1_RS13995
uniprot id: B8JE52
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

455488:A2CP1 RS15250
gene id: 455488:A2CP1_RS15250
uniprot id: B8JFI3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS01060
gene id: 455488:A2CP1_RS01060
uniprot id: B8J8X4
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

455488:A2CP1 RS12625
gene id: 455488:A2CP1_RS12625
uniprot id: B8JCA4
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

455488:A2CP1 RS13410
gene id: 455488:A2CP1_RS13410
uniprot id: B8JDF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

455488:A2CP1 RS01265
gene id: 455488:A2CP1_RS01265
uniprot id: B8J916
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

455488:A2CP1 RS01790
gene id: 455488:A2CP1_RS01790
uniprot id: B8JA17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

455488:A2CP1 RS00710
gene id: 455488:A2CP1_RS00710
uniprot id: B8J808
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

455488:A2CP1 RS12895
gene id: 455488:A2CP1_RS12895
uniprot id: B8JCF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

455488:A2CP1 RS02050
gene id: 455488:A2CP1_RS02050
uniprot id: B8JAW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

455488:A2CP1 RS05095
gene id: 455488:A2CP1_RS05095
uniprot id: B8JF18
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

455488:A2CP1 RS21885
gene id: 455488:A2CP1_RS21885
uniprot id: B8JBQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

455488:A2CP1 RS00665
gene id: 455488:A2CP1_RS00665
uniprot id: B8J7Z9
names: Similarity
messages: Belongs to the peptidase S9C family.

455488:A2CP1 RS04315
gene id: 455488:A2CP1_RS04315
uniprot id: B8JDX6
names: Similarity
messages: Belongs to the glutamate synthase family.

455488:A2CP1 RS21570
gene id: 455488:A2CP1_RS21570
uniprot id: B8JBJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

455488:A2CP1 RS12350
gene id: 455488:A2CP1_RS12350
uniprot id: B8JBG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

455488:A2CP1 RS07695
gene id: 455488:A2CP1_RS07695
uniprot id: B8J521
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS05115
gene id: 455488:A2CP1_RS05115
uniprot id: B8JF22
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

455488:A2CP1 RS04550
gene id: 455488:A2CP1_RS04550
uniprot id: B8JEE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

455488:A2CP1 RS17860
gene id: 455488:A2CP1_RS17860
uniprot id: B8J5X7
names: Similarity
messages: Belongs to the peptidase S66 family.

455488:A2CP1 RS22065
gene id: 455488:A2CP1_RS22065
uniprot id: B8JBU4
names: Subcellular Location Annotation
messages: Cytoplasm

455488:A2CP1 RS02105
gene id: 455488:A2CP1_RS02105
uniprot id: B8JAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

455488:A2CP1 RS05015
gene id: 455488:A2CP1_RS05015
uniprot id: B8JF01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

455488:A2CP1 RS21085
gene id: 455488:A2CP1_RS21085
uniprot id: B8JAK5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

455488:A2CP1 RS22180
gene id: 455488:A2CP1_RS22180
uniprot id: B8JCK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

455488:A2CP1 RS18085
gene id: 455488:A2CP1_RS18085
uniprot id: B8J623
names: Similarity
messages: Belongs to the histone deacetylase family.

455488:A2CP1 RS03805
gene id: 455488:A2CP1_RS03805
uniprot id: B8JDM2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS00015
gene id: 455488:A2CP1_RS00015
uniprot id: B8J6Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

455488:A2CP1 RS14210
gene id: 455488:A2CP1_RS14210
uniprot id: B8JE91
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

455488:A2CP1 RS19745
gene id: 455488:A2CP1_RS19745
uniprot id: B8J8F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

455488:A2CP1 RS09345
gene id: 455488:A2CP1_RS09345
uniprot id: B8J714
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

455488:A2CP1 RS10380
gene id: 455488:A2CP1_RS10380
uniprot id: B8J8A9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS07715
gene id: 455488:A2CP1_RS07715
uniprot id: B8J525
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

455488:A2CP1 RS01525
gene id: 455488:A2CP1_RS01525
uniprot id: B8J9W3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS11050
gene id: 455488:A2CP1_RS11050
uniprot id: B8J9D0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

455488:A2CP1 RS06165
gene id: 455488:A2CP1_RS06165
uniprot id: B8JFZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

455488:A2CP1 RS22310
gene id: 455488:A2CP1_RS22310
uniprot id: B8JCN1
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS11875
gene id: 455488:A2CP1_RS11875
uniprot id: B8JB74
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

455488:A2CP1 RS00595
gene id: 455488:A2CP1_RS00595
uniprot id: B8J7Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

455488:A2CP1 RS11410
gene id: 455488:A2CP1_RS11410
uniprot id: B8JA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

455488:A2CP1 RS10030
gene id: 455488:A2CP1_RS10030
uniprot id: B8J839
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

455488:A2CP1 RS21435
gene id: 455488:A2CP1_RS21435
uniprot id: B8JAS6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS01480
gene id: 455488:A2CP1_RS01480
uniprot id: B8J9V4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS13480
gene id: 455488:A2CP1_RS13480
uniprot id: B8JDG4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

455488:A2CP1 RS22770
gene id: 455488:A2CP1_RS22770
uniprot id: B8JFA2
names: Similarity
messages: Belongs to the ParB family.

455488:A2CP1 RS21280
gene id: 455488:A2CP1_RS21280
uniprot id: B8JAP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

455488:A2CP1 RS17830
gene id: 455488:A2CP1_RS17830
uniprot id: B8J5K4
names: Similarity
messages: Belongs to the histone deacetylase family.

455488:A2CP1 RS07075
gene id: 455488:A2CP1_RS07075
uniprot id: B8JH50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

455488:A2CP1 RS17735
gene id: 455488:A2CP1_RS17735
uniprot id: B8J5I5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

455488:A2CP1 RS21710
gene id: 455488:A2CP1_RS21710
uniprot id: B8JBM2
names: Similarity
messages: Belongs to the peptidase A31 family.

455488:A2CP1 RS14530
gene id: 455488:A2CP1_RS14530
uniprot id: B8JES2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

455488:A2CP1 RS10945
gene id: 455488:A2CP1_RS10945
uniprot id: B8J9B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS04405
gene id: 455488:A2CP1_RS04405
uniprot id: B8JEB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS04330
gene id: 455488:A2CP1_RS04330
uniprot id: B8JDX9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS16275
gene id: 455488:A2CP1_RS16275
uniprot id: B8JGS9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

455488:A2CP1 RS03740
gene id: 455488:A2CP1_RS03740
uniprot id: B8JDL1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

455488:A2CP1 RS00520
gene id: 455488:A2CP1_RS00520
uniprot id: B8J7X0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

455488:A2CP1 RS13795
gene id: 455488:A2CP1_RS13795
uniprot id: B8JE12
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

455488:A2CP1 RS00685
gene id: 455488:A2CP1_RS00685
uniprot id: B8J803
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

455488:A2CP1 RS06125
gene id: 455488:A2CP1_RS06125
uniprot id: B8JFY2
names: Similarity
messages: Belongs to the TlyA family.

455488:A2CP1 RS07930
gene id: 455488:A2CP1_RS07930
uniprot id: B8J568
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS06015
gene id: 455488:A2CP1_RS06015
uniprot id: B8JFW1
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

455488:A2CP1 RS22630
gene id: 455488:A2CP1_RS22630
uniprot id: B8JCV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

455488:A2CP1 RS06910
gene id: 455488:A2CP1_RS06910
uniprot id: B8JH17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS10305
gene id: 455488:A2CP1_RS10305
uniprot id: B8J894
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

455488:A2CP1 RS07110
gene id: 455488:A2CP1_RS07110
uniprot id: B8JH57
names: Similarity
messages: Belongs to the RecJ family.

455488:A2CP1 RS02795
gene id: 455488:A2CP1_RS02795
uniprot id: B8JBZ7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

455488:A2CP1 RS09400
gene id: 455488:A2CP1_RS09400
uniprot id: B8J724
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

455488:A2CP1 RS11570
gene id: 455488:A2CP1_RS11570
uniprot id: B8JAC1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

455488:A2CP1 RS04630
gene id: 455488:A2CP1_RS04630
uniprot id: B8JEF7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

455488:A2CP1 RS12260
gene id: 455488:A2CP1_RS12260
uniprot id: B8JBE5
names: Similarity
messages: Belongs to the peptidase S49 family.

455488:A2CP1 RS06885
gene id: 455488:A2CP1_RS06885
uniprot id: B8JH12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

455488:A2CP1 RS06895
gene id: 455488:A2CP1_RS06895
uniprot id: B8JH14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS07390
gene id: 455488:A2CP1_RS07390
uniprot id: B8JHB3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

455488:A2CP1 RS22610
gene id: 455488:A2CP1_RS22610
uniprot id: B8JCU6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS10165
gene id: 455488:A2CP1_RS10165
uniprot id: B8J866
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

455488:A2CP1 RS21705
gene id: 455488:A2CP1_RS21705
uniprot id: B8JBM1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

455488:A2CP1 RS10515
gene id: 455488:A2CP1_RS10515
uniprot id: B8J8D6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

455488:A2CP1 RS07750
gene id: 455488:A2CP1_RS07750
uniprot id: B8J532
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS05305
gene id: 455488:A2CP1_RS05305
uniprot id: B8JF59
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS17635
gene id: 455488:A2CP1_RS17635
uniprot id: B8J5H0
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS20460
gene id: 455488:A2CP1_RS20460
uniprot id: B8J9J3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS11565
gene id: 455488:A2CP1_RS11565
uniprot id: B8JAC0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

455488:A2CP1 RS14765
gene id: 455488:A2CP1_RS14765
uniprot id: B8JEW7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

455488:A2CP1 RS10885
gene id: 455488:A2CP1_RS10885
uniprot id: B8J999
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

455488:A2CP1 RS12180
gene id: 455488:A2CP1_RS12180
uniprot id: B8JBD0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

455488:A2CP1 RS18065
gene id: 455488:A2CP1_RS18065
uniprot id: B8J619
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00565
gene id: 455488:A2CP1_RS00565
uniprot id: B8J7X9
names: Similarity
messages: Belongs to the UPF0234 family.

455488:A2CP1 RS16330
gene id: 455488:A2CP1_RS16330
uniprot id: B8JGU0
names: Similarity
messages: Belongs to the DEAD box helicase family.

455488:A2CP1 RS21420
gene id: 455488:A2CP1_RS21420
uniprot id: B8JAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

455488:A2CP1 RS06335
gene id: 455488:A2CP1_RS06335
uniprot id: B8JGE0
names: Similarity
messages: Belongs to the peptidase S49 family.

455488:A2CP1 RS05005
gene id: 455488:A2CP1_RS05005
uniprot id: B8JEZ9
names: Similarity
messages: Belongs to the archease family.

455488:A2CP1 RS21875
gene id: 455488:A2CP1_RS21875
uniprot id: B8JBQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

455488:A2CP1 RS17235
gene id: 455488:A2CP1_RS17235
uniprot id: B8JHN9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

455488:A2CP1 RS11300
gene id: 455488:A2CP1_RS11300
uniprot id: B8JA67
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

455488:A2CP1 RS01195
gene id: 455488:A2CP1_RS01195
uniprot id: B8J902
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

455488:A2CP1 RS01570
gene id: 455488:A2CP1_RS01570
uniprot id: B8J9X2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

455488:A2CP1 RS19335
gene id: 455488:A2CP1_RS19335
uniprot id: B8J7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

455488:A2CP1 RS20120
gene id: 455488:A2CP1_RS20120
uniprot id: B8J8M9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

455488:A2CP1 RS08885
gene id: 455488:A2CP1_RS08885
uniprot id: B8J6D1
names: Similarity
messages: Belongs to the leucine-binding protein family.

455488:A2CP1 RS09955
gene id: 455488:A2CP1_RS09955
uniprot id: B8J824
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

455488:A2CP1 RS07745
gene id: 455488:A2CP1_RS07745
uniprot id: B8J531
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS19710
gene id: 455488:A2CP1_RS19710
uniprot id: B8J8E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

455488:A2CP1 RS19130
gene id: 455488:A2CP1_RS19130
uniprot id: B8J7E0
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS14500
gene id: 455488:A2CP1_RS14500
uniprot id: B8JER6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

455488:A2CP1 RS04690
gene id: 455488:A2CP1_RS04690
uniprot id: B8JEG8
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS02525
gene id: 455488:A2CP1_RS02525
uniprot id: B8JB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

455488:A2CP1 RS01315
gene id: 455488:A2CP1_RS01315
uniprot id: B8J926
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS04215
gene id: 455488:A2CP1_RS04215
uniprot id: B8JDV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

455488:A2CP1 RS18525
gene id: 455488:A2CP1_RS18525
uniprot id: B8J6N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

455488:A2CP1 RS06840
gene id: 455488:A2CP1_RS06840
uniprot id: B8JGN4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

455488:A2CP1 RS11880
gene id: 455488:A2CP1_RS11880
uniprot id: B8JB75
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

455488:A2CP1 RS06080
gene id: 455488:A2CP1_RS06080
uniprot id: B8JFX3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS17145
gene id: 455488:A2CP1_RS17145
uniprot id: B8JHM5
names: Similarity
messages: Belongs to the peptidase M24B family.

455488:A2CP1 RS09965
gene id: 455488:A2CP1_RS09965
uniprot id: B8J826
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

455488:A2CP1 RS13035
gene id: 455488:A2CP1_RS13035
uniprot id: B8JCI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

455488:A2CP1 RS19280
gene id: 455488:A2CP1_RS19280
uniprot id: B8J7H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

455488:A2CP1 RS22660
gene id: 455488:A2CP1_RS22660
uniprot id: B8JCV6
names: Similarity
messages: Belongs to the ParB family.

455488:A2CP1 RS01435
gene id: 455488:A2CP1_RS01435
uniprot id: B8J9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

455488:A2CP1 RS13985
gene id: 455488:A2CP1_RS13985
uniprot id: B8JE50
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS09450
gene id: 455488:A2CP1_RS09450
uniprot id: B8J734
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

455488:A2CP1 RS03245
gene id: 455488:A2CP1_RS03245
uniprot id: B8JCY0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

455488:A2CP1 RS01505
gene id: 455488:A2CP1_RS01505
uniprot id: B8J9V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

455488:A2CP1 RS19520
gene id: 455488:A2CP1_RS19520
uniprot id: B8J7L7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

455488:A2CP1 RS12965
gene id: 455488:A2CP1_RS12965
uniprot id: B8JCH0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS16390
gene id: 455488:A2CP1_RS16390
uniprot id: B8JGV2
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

455488:A2CP1 RS12020
gene id: 455488:A2CP1_RS12020
uniprot id: B8JB98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

455488:A2CP1 RS13860
gene id: 455488:A2CP1_RS13860
uniprot id: B8JE25
names: Similarity
messages: Belongs to the AHA1 family.

455488:A2CP1 RS14705
gene id: 455488:A2CP1_RS14705
uniprot id: B8JEV5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

455488:A2CP1 RS10630
gene id: 455488:A2CP1_RS10630
uniprot id: B8J950
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

455488:A2CP1 RS14745
gene id: 455488:A2CP1_RS14745
uniprot id: B8JEW3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

455488:A2CP1 RS00385
gene id: 455488:A2CP1_RS00385
uniprot id: B8J7U3
names: Subcellular Location Annotation
messages: Nucleus

455488:A2CP1 RS19835
gene id: 455488:A2CP1_RS19835
uniprot id: B8J8H3
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

455488:A2CP1 RS20745
gene id: 455488:A2CP1_RS20745
uniprot id: B8J9Q0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

455488:A2CP1 RS12840
gene id: 455488:A2CP1_RS12840
uniprot id: B8JCE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

455488:A2CP1 RS01575
gene id: 455488:A2CP1_RS01575
uniprot id: B8J9X3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

455488:A2CP1 RS21900
gene id: 455488:A2CP1_RS21900
uniprot id: B8JBR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS07880
gene id: 455488:A2CP1_RS07880
uniprot id: B8J558
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

455488:A2CP1 RS09750
gene id: 455488:A2CP1_RS09750
uniprot id: B8J794
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

455488:A2CP1 RS20680
gene id: 455488:A2CP1_RS20680
uniprot id: B8J9N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

455488:A2CP1 RS05880
gene id: 455488:A2CP1_RS05880
uniprot id: B8JFT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

455488:A2CP1 RS21095
gene id: 455488:A2CP1_RS21095
uniprot id: B8JAK7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

455488:A2CP1 RS13105
gene id: 455488:A2CP1_RS13105
uniprot id: B8JD89
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

455488:A2CP1 RS18530
gene id: 455488:A2CP1_RS18530
uniprot id: B8J6N4
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

455488:A2CP1 RS20875
gene id: 455488:A2CP1_RS20875
uniprot id: B8J9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

455488:A2CP1 RS06620
gene id: 455488:A2CP1_RS06620
uniprot id: B8JGJ6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

455488:A2CP1 RS04755
gene id: 455488:A2CP1_RS04755
uniprot id: B8JEI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

455488:A2CP1 RS08440
gene id: 455488:A2CP1_RS08440
uniprot id: B8J5S7
names: Similarity
messages: Belongs to the ketopantoate reductase family.

455488:A2CP1 RS21730
gene id: 455488:A2CP1_RS21730
uniprot id: B8JBM6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

455488:A2CP1 RS14775
gene id: 455488:A2CP1_RS14775
uniprot id: B8JEW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS17500
gene id: 455488:A2CP1_RS17500
uniprot id: B8J5E4
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

455488:A2CP1 RS11885
gene id: 455488:A2CP1_RS11885
uniprot id: B8JB76
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS11540
gene id: 455488:A2CP1_RS11540
uniprot id: B8JAB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

455488:A2CP1 RS14430
gene id: 455488:A2CP1_RS14430
uniprot id: B8JEQ2
names: Similarity
messages: Belongs to the universal stress protein A family.

455488:A2CP1 RS03995
gene id: 455488:A2CP1_RS03995
uniprot id: B8JDR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

455488:A2CP1 RS21745
gene id: 455488:A2CP1_RS21745
uniprot id: B8JBM9
names: Similarity
messages: Belongs to the sigma-54 factor family.

455488:A2CP1 RS00875
gene id: 455488:A2CP1_RS00875
uniprot id: B8J8T5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

455488:A2CP1 RS09990
gene id: 455488:A2CP1_RS09990
uniprot id: B8J831
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

455488:A2CP1 RS20505
gene id: 455488:A2CP1_RS20505
uniprot id: B8J9K2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

455488:A2CP1 RS13520
gene id: 455488:A2CP1_RS13520
uniprot id: B8JDH2
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS03065
gene id: 455488:A2CP1_RS03065
uniprot id: B8JC50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

455488:A2CP1 RS02500
gene id: 455488:A2CP1_RS02500
uniprot id: B8JB48
names: Similarity
messages: Belongs to the HypD family.

455488:A2CP1 RS04780
gene id: 455488:A2CP1_RS04780
uniprot id: B8JEI6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

455488:A2CP1 RS13905
gene id: 455488:A2CP1_RS13905
uniprot id: B8JE34
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

455488:A2CP1 RS15350
gene id: 455488:A2CP1_RS15350
uniprot id: B8JFK3
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

455488:A2CP1 RS17870
gene id: 455488:A2CP1_RS17870
uniprot id: B8J5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

455488:A2CP1 RS08805
gene id: 455488:A2CP1_RS08805
uniprot id: B8J6B5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS03005
gene id: 455488:A2CP1_RS03005
uniprot id: B8JC38
names: Similarity
messages: Belongs to the peptidase M16 family.

455488:A2CP1 RS02135
gene id: 455488:A2CP1_RS02135
uniprot id: B8JAX7
names: Similarity
messages: Belongs to the pirin family.

455488:A2CP1 RS18130
gene id: 455488:A2CP1_RS18130
uniprot id: B8J632
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

455488:A2CP1 RS16695
gene id: 455488:A2CP1_RS16695
uniprot id: B8JHD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

455488:A2CP1 RS04865
gene id: 455488:A2CP1_RS04865
uniprot id: B8JEK2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS09125
gene id: 455488:A2CP1_RS09125
uniprot id: B8J6I0
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS13220
gene id: 455488:A2CP1_RS13220
uniprot id: B8JDB2
names: Similarity
messages: Belongs to the universal stress protein A family.

455488:A2CP1 RS18200
gene id: 455488:A2CP1_RS18200
uniprot id: B8J648
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

455488:A2CP1 RS18720
gene id: 455488:A2CP1_RS18720
uniprot id: B8J6R9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

455488:A2CP1 RS12630
gene id: 455488:A2CP1_RS12630
uniprot id: B8JCA5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

455488:A2CP1 RS07570
gene id: 455488:A2CP1_RS07570
uniprot id: B8J4Z6
names: Similarity
messages: Belongs to the peptidase S58 family.

455488:A2CP1 RS04440
gene id: 455488:A2CP1_RS04440
uniprot id: B8JEB9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

455488:A2CP1 RS00270
gene id: 455488:A2CP1_RS00270
uniprot id: B8J7S0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

455488:A2CP1 RS16505
gene id: 455488:A2CP1_RS16505
uniprot id: B8JGX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

455488:A2CP1 RS14990
gene id: 455488:A2CP1_RS14990
uniprot id: B8JFD0
names: Similarity
messages: Belongs to the asparagine synthetase family.

455488:A2CP1 RS00840
gene id: 455488:A2CP1_RS00840
uniprot id: B8J8S8
names: Subcellular Location Annotation
messages: Cytoplasm

455488:A2CP1 RS10200
gene id: 455488:A2CP1_RS10200
uniprot id: B8J873
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

455488:A2CP1 RS09795
gene id: 455488:A2CP1_RS09795
uniprot id: B8J7A3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

455488:A2CP1 RS22640
gene id: 455488:A2CP1_RS22640
uniprot id: B8JCV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

455488:A2CP1 RS07560
gene id: 455488:A2CP1_RS07560
uniprot id: B8J4Z4
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS15065
gene id: 455488:A2CP1_RS15065
uniprot id: B8JFE6
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

455488:A2CP1 RS00205
gene id: 455488:A2CP1_RS00205
uniprot id: B8J7Q8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS01330
gene id: 455488:A2CP1_RS01330
uniprot id: B8J929
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

455488:A2CP1 RS05405
gene id: 455488:A2CP1_RS05405
uniprot id: B8JF77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS14385
gene id: 455488:A2CP1_RS14385
uniprot id: B8JEP4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

455488:A2CP1 RS13145
gene id: 455488:A2CP1_RS13145
uniprot id: B8JD97
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

455488:A2CP1 RS03465
gene id: 455488:A2CP1_RS03465
uniprot id: B8JD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

455488:A2CP1 RS01490
gene id: 455488:A2CP1_RS01490
uniprot id: B8J9V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

455488:A2CP1 RS19910
gene id: 455488:A2CP1_RS19910
uniprot id: B8J8I8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS15700
gene id: 455488:A2CP1_RS15700
uniprot id: B8JG49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS02655
gene id: 455488:A2CP1_RS02655
uniprot id: B8JBW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

455488:A2CP1 RS07000
gene id: 455488:A2CP1_RS07000
uniprot id: B8JH35
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS17935
gene id: 455488:A2CP1_RS17935
uniprot id: B8J5Z3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

455488:A2CP1 RS15535
gene id: 455488:A2CP1_RS15535
uniprot id: B8JG15
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS11845
gene id: 455488:A2CP1_RS11845
uniprot id: B8JB68
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

455488:A2CP1 RS01865
gene id: 455488:A2CP1_RS01865
uniprot id: B8JA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

455488:A2CP1 RS05920
gene id: 455488:A2CP1_RS05920
uniprot id: B8JFU2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

455488:A2CP1 RS17570
gene id: 455488:A2CP1_RS17570
uniprot id: B8J5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS13490
gene id: 455488:A2CP1_RS13490
uniprot id: B8JDG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

455488:A2CP1 RS20500
gene id: 455488:A2CP1_RS20500
uniprot id: B8J9K1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

455488:A2CP1 RS15950
gene id: 455488:A2CP1_RS15950
uniprot id: B8JGA0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

455488:A2CP1 RS19670
gene id: 455488:A2CP1_RS19670
uniprot id: B8J8E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

455488:A2CP1 RS21790
gene id: 455488:A2CP1_RS21790
uniprot id: B8JBN8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

455488:A2CP1 RS10485
gene id: 455488:A2CP1_RS10485
uniprot id: B8J8C9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

455488:A2CP1 RS06145
gene id: 455488:A2CP1_RS06145
uniprot id: B8JFY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

455488:A2CP1 RS08705
gene id: 455488:A2CP1_RS08705
uniprot id: B8J695
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS07330
gene id: 455488:A2CP1_RS07330
uniprot id: B8JHA1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

455488:A2CP1 RS18295
gene id: 455488:A2CP1_RS18295
uniprot id: B8J667
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

455488:A2CP1 RS06305
gene id: 455488:A2CP1_RS06305
uniprot id: B8JGD4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

455488:A2CP1 RS19715
gene id: 455488:A2CP1_RS19715
uniprot id: B8J8E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

455488:A2CP1 RS19000
gene id: 455488:A2CP1_RS19000
uniprot id: B8J6X4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

455488:A2CP1 RS22020
gene id: 455488:A2CP1_RS22020
uniprot id: B8JBT5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

455488:A2CP1 RS12660
gene id: 455488:A2CP1_RS12660
uniprot id: B8JCB1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS18175
gene id: 455488:A2CP1_RS18175
uniprot id: B8J643
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS12335
gene id: 455488:A2CP1_RS12335
uniprot id: B8JBG0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

455488:A2CP1 RS13325
gene id: 455488:A2CP1_RS13325
uniprot id: B8JDD3
names: Subcellular Location Annotation
messages: Cytoplasm

455488:A2CP1 RS06960
gene id: 455488:A2CP1_RS06960
uniprot id: B8JH27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS21950
gene id: 455488:A2CP1_RS21950
uniprot id: B8JBS1
names: Similarity
messages: Belongs to the neutral ceramidase family.

455488:A2CP1 RS00770
gene id: 455488:A2CP1_RS00770
uniprot id: B8J8R4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

455488:A2CP1 RS04295
gene id: 455488:A2CP1_RS04295
uniprot id: B8JDX2
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS08645
gene id: 455488:A2CP1_RS08645
uniprot id: B8J5W7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

455488:A2CP1 RS22355
gene id: 455488:A2CP1_RS22355
uniprot id: B8JCP4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS20580
gene id: 455488:A2CP1_RS20580
uniprot id: B8J9L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

455488:A2CP1 RS04450
gene id: 455488:A2CP1_RS04450
uniprot id: B8JEC1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

455488:A2CP1 RS11535
gene id: 455488:A2CP1_RS11535
uniprot id: B8JAB4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

455488:A2CP1 RS04345
gene id: 455488:A2CP1_RS04345
uniprot id: B8JDY2
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

455488:A2CP1 RS18305
gene id: 455488:A2CP1_RS18305
uniprot id: B8J669
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

455488:A2CP1 RS00880
gene id: 455488:A2CP1_RS00880
uniprot id: B8J8T6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

455488:A2CP1 RS09020
gene id: 455488:A2CP1_RS09020
uniprot id: B8J6F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

455488:A2CP1 RS02015
gene id: 455488:A2CP1_RS02015
uniprot id: B8JAV3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

455488:A2CP1 RS16265
gene id: 455488:A2CP1_RS16265
uniprot id: B8JGS6
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS05085
gene id: 455488:A2CP1_RS05085
uniprot id: B8JF15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

455488:A2CP1 RS19235
gene id: 455488:A2CP1_RS19235
uniprot id: B8J7G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS03700
gene id: 455488:A2CP1_RS03700
uniprot id: B8JD70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

455488:A2CP1 RS16745
gene id: 455488:A2CP1_RS16745
uniprot id: B8JHE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

455488:A2CP1 RS08310
gene id: 455488:A2CP1_RS08310
uniprot id: B8J5Q0
names: Similarity
messages: Belongs to the peptidase S33 family.

455488:A2CP1 RS03410
gene id: 455488:A2CP1_RS03410
uniprot id: B8JD13
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

455488:A2CP1 RS22185
gene id: 455488:A2CP1_RS22185
uniprot id: B8JCK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS03000
gene id: 455488:A2CP1_RS03000
uniprot id: B8JC37
names: Similarity
messages: Belongs to the hemerythrin family.

455488:A2CP1 RS20495
gene id: 455488:A2CP1_RS20495
uniprot id: B8J9K0
names: Similarity
messages: Belongs to the FPG family.

455488:A2CP1 RS04725
gene id: 455488:A2CP1_RS04725
uniprot id: B8JEH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS16660
gene id: 455488:A2CP1_RS16660
uniprot id: B8JHD1
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS16315
gene id: 455488:A2CP1_RS16315
uniprot id: B8JGT7
names: Similarity
messages: Belongs to the peptidase C56 family.

455488:A2CP1 RS10490
gene id: 455488:A2CP1_RS10490
uniprot id: B8J8D0
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS18215
gene id: 455488:A2CP1_RS18215
uniprot id: B8J651
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

455488:A2CP1 RS21680
gene id: 455488:A2CP1_RS21680
uniprot id: B8JBL6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

455488:A2CP1 RS06100
gene id: 455488:A2CP1_RS06100
uniprot id: B8JFX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

455488:A2CP1 RS06135
gene id: 455488:A2CP1_RS06135
uniprot id: B8JFY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

455488:A2CP1 RS17720
gene id: 455488:A2CP1_RS17720
uniprot id: B8J5I2
names: Similarity
messages: Belongs to the GSP E family.

455488:A2CP1 RS10665
gene id: 455488:A2CP1_RS10665
uniprot id: B8J957
names: Similarity
messages: Belongs to the heat shock protein 70 family.

455488:A2CP1 RS06105
gene id: 455488:A2CP1_RS06105
uniprot id: B8JFX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

455488:A2CP1 RS10155
gene id: 455488:A2CP1_RS10155
uniprot id: B8J864
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

455488:A2CP1 RS10940
gene id: 455488:A2CP1_RS10940
uniprot id: B8J9B0
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

455488:A2CP1 RS00920
gene id: 455488:A2CP1_RS00920
uniprot id: B8J8U5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS09825
gene id: 455488:A2CP1_RS09825
uniprot id: B8J7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

455488:A2CP1 RS21450
gene id: 455488:A2CP1_RS21450
uniprot id: B8JAS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS10250
gene id: 455488:A2CP1_RS10250
uniprot id: B8J883
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

455488:A2CP1 RS21400
gene id: 455488:A2CP1_RS21400
uniprot id: B8JAR9
names: Similarity
messages: Belongs to the arginase family.

455488:A2CP1 RS08015
gene id: 455488:A2CP1_RS08015
uniprot id: B8J585
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

455488:A2CP1 RS13930
gene id: 455488:A2CP1_RS13930
uniprot id: B8JE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

455488:A2CP1 RS21580
gene id: 455488:A2CP1_RS21580
uniprot id: B8JBJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

455488:A2CP1 RS01040
gene id: 455488:A2CP1_RS01040
uniprot id: B8J8X0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

455488:A2CP1 RS20610
gene id: 455488:A2CP1_RS20610
uniprot id: B8J9M4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

455488:A2CP1 RS07990
gene id: 455488:A2CP1_RS07990
uniprot id: B8J580
names: Similarity
messages: Belongs to the band 7/mec-2 family.

455488:A2CP1 RS12330
gene id: 455488:A2CP1_RS12330
uniprot id: B8JBF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

455488:A2CP1 RS14795
gene id: 455488:A2CP1_RS14795
uniprot id: B8JEX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

455488:A2CP1 RS22285
gene id: 455488:A2CP1_RS22285
uniprot id: B8JCM6
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS21245
gene id: 455488:A2CP1_RS21245
uniprot id: B8JAN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

455488:A2CP1 RS09120
gene id: 455488:A2CP1_RS09120
uniprot id: B8J6H9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS05945
gene id: 455488:A2CP1_RS05945
uniprot id: B8JFU7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

455488:A2CP1 RS06070
gene id: 455488:A2CP1_RS06070
uniprot id: B8JFX1
names: Similarity
messages: Belongs to the UPF0235 family.

455488:A2CP1 RS01545
gene id: 455488:A2CP1_RS01545
uniprot id: B8J9W7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

455488:A2CP1 RS21260
gene id: 455488:A2CP1_RS21260
uniprot id: B8JAP1
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

455488:A2CP1 RS08515
gene id: 455488:A2CP1_RS08515
uniprot id: B8J5U2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

455488:A2CP1 RS19660
gene id: 455488:A2CP1_RS19660
uniprot id: B8J7P4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

455488:A2CP1 RS19145
gene id: 455488:A2CP1_RS19145
uniprot id: B8J7E3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS05380
gene id: 455488:A2CP1_RS05380
uniprot id: B8JF73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

455488:A2CP1 RS08020
gene id: 455488:A2CP1_RS08020
uniprot id: B8J586
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

455488:A2CP1 RS04030
gene id: 455488:A2CP1_RS04030
uniprot id: B8JDR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

455488:A2CP1 RS04185
gene id: 455488:A2CP1_RS04185
uniprot id: B8JDV0
names: Similarity
messages: Belongs to the peptidase S9C family.

455488:A2CP1 RS17025
gene id: 455488:A2CP1_RS17025
uniprot id: B8JHK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS11700
gene id: 455488:A2CP1_RS11700
uniprot id: B8JAE7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

455488:A2CP1 RS13365
gene id: 455488:A2CP1_RS13365
uniprot id: B8JDE1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

455488:A2CP1 RS10005
gene id: 455488:A2CP1_RS10005
uniprot id: B8J834
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

455488:A2CP1 RS13900
gene id: 455488:A2CP1_RS13900
uniprot id: B8JE33
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

455488:A2CP1 RS11580
gene id: 455488:A2CP1_RS11580
uniprot id: B8JAC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

455488:A2CP1 RS11870
gene id: 455488:A2CP1_RS11870
uniprot id: B8JB73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

455488:A2CP1 RS11060
gene id: 455488:A2CP1_RS11060
uniprot id: B8J9D2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

455488:A2CP1 RS14135
gene id: 455488:A2CP1_RS14135
uniprot id: B8JE76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS07475
gene id: 455488:A2CP1_RS07475
uniprot id: B8JHD0
names: Similarity
messages: Belongs to the GARS family.

455488:A2CP1 RS15560
gene id: 455488:A2CP1_RS15560
uniprot id: B8JG20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

455488:A2CP1 RS03800
gene id: 455488:A2CP1_RS03800
uniprot id: B8JDM1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

455488:A2CP1 RS11525
gene id: 455488:A2CP1_RS11525
uniprot id: B8JAB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS20650
gene id: 455488:A2CP1_RS20650
uniprot id: B8J9N2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS06430
gene id: 455488:A2CP1_RS06430
uniprot id: B8JGF9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

455488:A2CP1 RS11035
gene id: 455488:A2CP1_RS11035
uniprot id: B8J9C7
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS10130
gene id: 455488:A2CP1_RS10130
uniprot id: B8J859
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

455488:A2CP1 RS00470
gene id: 455488:A2CP1_RS00470
uniprot id: B8J7W0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS13965
gene id: 455488:A2CP1_RS13965
uniprot id: B8JE46
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

455488:A2CP1 RS12285
gene id: 455488:A2CP1_RS12285
uniprot id: B8JBF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

455488:A2CP1 RS09740
gene id: 455488:A2CP1_RS09740
uniprot id: B8J792
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

455488:A2CP1 RS15890
gene id: 455488:A2CP1_RS15890
uniprot id: B8JG88
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

455488:A2CP1 RS22430
gene id: 455488:A2CP1_RS22430
uniprot id: B8JCR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

455488:A2CP1 RS12125
gene id: 455488:A2CP1_RS12125
uniprot id: B8JBB8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

455488:A2CP1 RS06155
gene id: 455488:A2CP1_RS06155
uniprot id: B8JFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

455488:A2CP1 RS14475
gene id: 455488:A2CP1_RS14475
uniprot id: B8JER1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

455488:A2CP1 RS18895
gene id: 455488:A2CP1_RS18895
uniprot id: B8J6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

455488:A2CP1 RS10230
gene id: 455488:A2CP1_RS10230
uniprot id: B8J879
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

455488:A2CP1 RS09765
gene id: 455488:A2CP1_RS09765
uniprot id: B8J797
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS13620
gene id: 455488:A2CP1_RS13620
uniprot id: B8JDJ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

455488:A2CP1 RS09900
gene id: 455488:A2CP1_RS09900
uniprot id: B8J814
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

455488:A2CP1 RS03525
gene id: 455488:A2CP1_RS03525
uniprot id: B8JD35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

455488:A2CP1 RS13515
gene id: 455488:A2CP1_RS13515
uniprot id: B8JDH1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS14170
gene id: 455488:A2CP1_RS14170
uniprot id: B8JE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS19755
gene id: 455488:A2CP1_RS19755
uniprot id: B8J8F7
names: Similarity
messages: Belongs to the AHA1 family.

455488:A2CP1 RS17565
gene id: 455488:A2CP1_RS17565
uniprot id: B8J5F7
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

455488:A2CP1 RS20050
gene id: 455488:A2CP1_RS20050
uniprot id: B8J8L5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS21395
gene id: 455488:A2CP1_RS21395
uniprot id: B8JAR8
names: Similarity
messages: Belongs to the hemerythrin family.

455488:A2CP1 RS21155
gene id: 455488:A2CP1_RS21155
uniprot id: B8JAL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

455488:A2CP1 RS06170
gene id: 455488:A2CP1_RS06170
uniprot id: B8JFZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

455488:A2CP1 RS03190
gene id: 455488:A2CP1_RS03190
uniprot id: B8JCW8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

455488:A2CP1 RS16675
gene id: 455488:A2CP1_RS16675
uniprot id: B8JHD4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS09465
gene id: 455488:A2CP1_RS09465
uniprot id: B8J737
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

455488:A2CP1 RS11105
gene id: 455488:A2CP1_RS11105
uniprot id: B8J9E1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

455488:A2CP1 RS22670
gene id: 455488:A2CP1_RS22670
uniprot id: B8JDK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

455488:A2CP1 RS01930
gene id: 455488:A2CP1_RS01930
uniprot id: B8JAT6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

455488:A2CP1 RS12900
gene id: 455488:A2CP1_RS12900
uniprot id: B8JCF7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

455488:A2CP1 RS12890
gene id: 455488:A2CP1_RS12890
uniprot id: B8JCF5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

455488:A2CP1 RS04415
gene id: 455488:A2CP1_RS04415
uniprot id: B8JEB4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

455488:A2CP1 RS13000
gene id: 455488:A2CP1_RS13000
uniprot id: B8JCH7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

455488:A2CP1 RS11405
gene id: 455488:A2CP1_RS11405
uniprot id: B8JA88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

455488:A2CP1 RS08740
gene id: 455488:A2CP1_RS08740
uniprot id: B8J6A2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

455488:A2CP1 RS00440
gene id: 455488:A2CP1_RS00440
uniprot id: B8J7V4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS00070
gene id: 455488:A2CP1_RS00070
uniprot id: B8J6Z2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

455488:A2CP1 RS17070
gene id: 455488:A2CP1_RS17070
uniprot id: B8JHL2
names: Similarity
messages: Belongs to the UPF0166 family.

455488:A2CP1 RS12095
gene id: 455488:A2CP1_RS12095
uniprot id: B8JBB2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

455488:A2CP1 RS07485
gene id: 455488:A2CP1_RS07485
uniprot id: B8J4X9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS08005
gene id: 455488:A2CP1_RS08005
uniprot id: B8J583
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

455488:A2CP1 RS04200
gene id: 455488:A2CP1_RS04200
uniprot id: B8JDV3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS05300
gene id: 455488:A2CP1_RS05300
uniprot id: B8JF58
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00705
gene id: 455488:A2CP1_RS00705
uniprot id: B8J807
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

455488:A2CP1 RS01420
gene id: 455488:A2CP1_RS01420
uniprot id: B8J9U2
names: Similarity
messages: Belongs to the class-I fumarase family.

455488:A2CP1 RS13670
gene id: 455488:A2CP1_RS13670
uniprot id: B8JDY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

455488:A2CP1 RS05965
gene id: 455488:A2CP1_RS05965
uniprot id: B8JFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

455488:A2CP1 RS06130
gene id: 455488:A2CP1_RS06130
uniprot id: B8JFY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

455488:A2CP1 RS03810
gene id: 455488:A2CP1_RS03810
uniprot id: B8JDM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

455488:A2CP1 RS21425
gene id: 455488:A2CP1_RS21425
uniprot id: B8JAS4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

455488:A2CP1 RS11635
gene id: 455488:A2CP1_RS11635
uniprot id: B8JAD4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

455488:A2CP1 RS09770
gene id: 455488:A2CP1_RS09770
uniprot id: B8J798
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS08700
gene id: 455488:A2CP1_RS08700
uniprot id: B8J694
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS19850
gene id: 455488:A2CP1_RS19850
uniprot id: B8J8H6
names: Similarity
messages: Belongs to the peptidase S41A family.

455488:A2CP1 RS07420
gene id: 455488:A2CP1_RS07420
uniprot id: B8JHB9
names: Similarity
messages: Belongs to the phosphopentomutase family.

455488:A2CP1 RS08335
gene id: 455488:A2CP1_RS08335
uniprot id: B8J5Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

455488:A2CP1 RS12695
gene id: 455488:A2CP1_RS12695
uniprot id: B8JCB8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

455488:A2CP1 RS16895
gene id: 455488:A2CP1_RS16895
uniprot id: B8JHH8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS05980
gene id: 455488:A2CP1_RS05980
uniprot id: B8JFV4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

455488:A2CP1 RS13330
gene id: 455488:A2CP1_RS13330
uniprot id: B8JDD4
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

455488:A2CP1 RS01725
gene id: 455488:A2CP1_RS01725
uniprot id: B8JA03
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

455488:A2CP1 RS11725
gene id: 455488:A2CP1_RS11725
uniprot id: B8JAF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

455488:A2CP1 RS10660
gene id: 455488:A2CP1_RS10660
uniprot id: B8J956
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

455488:A2CP1 RS22760
gene id: 455488:A2CP1_RS22760
uniprot id: B8JF97
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

455488:A2CP1 RS15970
gene id: 455488:A2CP1_RS15970
uniprot id: B8JGA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

455488:A2CP1 RS12455
gene id: 455488:A2CP1_RS12455
uniprot id: B8JC71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS18715
gene id: 455488:A2CP1_RS18715
uniprot id: B8J6R8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS00080
gene id: 455488:A2CP1_RS00080
uniprot id: B8J6Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

455488:A2CP1 RS13555
gene id: 455488:A2CP1_RS13555
uniprot id: B8JDH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

455488:A2CP1 RS03745
gene id: 455488:A2CP1_RS03745
uniprot id: B8JDL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

455488:A2CP1 RS06785
gene id: 455488:A2CP1_RS06785
uniprot id: B8JGM3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

455488:A2CP1 RS13065
gene id: 455488:A2CP1_RS13065
uniprot id: B8JD81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

455488:A2CP1 RS08900
gene id: 455488:A2CP1_RS08900
uniprot id: B8J6D4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

455488:A2CP1 RS03490
gene id: 455488:A2CP1_RS03490
uniprot id: B8JD28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

455488:A2CP1 RS13160
gene id: 455488:A2CP1_RS13160
uniprot id: B8JDA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

455488:A2CP1 RS17355
gene id: 455488:A2CP1_RS17355
uniprot id: B8J5B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

455488:A2CP1 RS19070
gene id: 455488:A2CP1_RS19070
uniprot id: B8J7C8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

455488:A2CP1 RS13440
gene id: 455488:A2CP1_RS13440
uniprot id: B8JDF6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

455488:A2CP1 RS00590
gene id: 455488:A2CP1_RS00590
uniprot id: B8J7Y4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

455488:A2CP1 RS00845
gene id: 455488:A2CP1_RS00845
uniprot id: B8J8S9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS06905
gene id: 455488:A2CP1_RS06905
uniprot id: B8JH16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

455488:A2CP1 RS21820
gene id: 455488:A2CP1_RS21820
uniprot id: B8JBP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

455488:A2CP1 RS07890
gene id: 455488:A2CP1_RS07890
uniprot id: B8J560
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

455488:A2CP1 RS17680
gene id: 455488:A2CP1_RS17680
uniprot id: B8J5H4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

455488:A2CP1 RS01485
gene id: 455488:A2CP1_RS01485
uniprot id: B8J9V5
names: Similarity
messages: Belongs to the FPG family.

455488:A2CP1 RS19720
gene id: 455488:A2CP1_RS19720
uniprot id: B8J8F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

455488:A2CP1 RS08410
gene id: 455488:A2CP1_RS08410
uniprot id: B8J5S1
names: Similarity
messages: Belongs to the SCO1/2 family.

455488:A2CP1 RS05280
gene id: 455488:A2CP1_RS05280
uniprot id: B8JF54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

455488:A2CP1 RS18275
gene id: 455488:A2CP1_RS18275
uniprot id: B8J663
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

455488:A2CP1 RS15740
gene id: 455488:A2CP1_RS15740
uniprot id: B8JG57
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

455488:A2CP1 RS19975
gene id: 455488:A2CP1_RS19975
uniprot id: B8J8K0
names: Similarity
messages: Belongs to the UPF0758 family.

455488:A2CP1 RS22335
gene id: 455488:A2CP1_RS22335
uniprot id: B8JCP0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

455488:A2CP1 RS06415
gene id: 455488:A2CP1_RS06415
uniprot id: B8JGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

455488:A2CP1 RS03575
gene id: 455488:A2CP1_RS03575
uniprot id: B8JD45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS12410
gene id: 455488:A2CP1_RS12410
uniprot id: B8JBH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS02710
gene id: 455488:A2CP1_RS02710
uniprot id: B8JBY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

455488:A2CP1 RS06875
gene id: 455488:A2CP1_RS06875
uniprot id: B8JH10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS05045
gene id: 455488:A2CP1_RS05045
uniprot id: B8JF07
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

455488:A2CP1 RS18765
gene id: 455488:A2CP1_RS18765
uniprot id: B8J6S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

455488:A2CP1 RS18970
gene id: 455488:A2CP1_RS18970
uniprot id: B8J6W9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

455488:A2CP1 RS01660
gene id: 455488:A2CP1_RS01660
uniprot id: B8J9Z0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS14510
gene id: 455488:A2CP1_RS14510
uniprot id: B8JER8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

455488:A2CP1 RS18000
gene id: 455488:A2CP1_RS18000
uniprot id: B8J606
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

455488:A2CP1 RS09935
gene id: 455488:A2CP1_RS09935
uniprot id: B8J821
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

455488:A2CP1 RS11090
gene id: 455488:A2CP1_RS11090
uniprot id: B8J9D8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

455488:A2CP1 RS20885
gene id: 455488:A2CP1_RS20885
uniprot id: B8J9S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS16780
gene id: 455488:A2CP1_RS16780
uniprot id: B8JHF5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

455488:A2CP1 RS12200
gene id: 455488:A2CP1_RS12200
uniprot id: B8JBD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

455488:A2CP1 RS11750
gene id: 455488:A2CP1_RS11750
uniprot id: B8JAF7
names: Similarity
messages: Belongs to the RecA family.

455488:A2CP1 RS09160
gene id: 455488:A2CP1_RS09160
uniprot id: B8J6I7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

455488:A2CP1 RS21460
gene id: 455488:A2CP1_RS21460
uniprot id: B8JAT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

455488:A2CP1 RS14095
gene id: 455488:A2CP1_RS14095
uniprot id: B8JE68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

455488:A2CP1 RS05320
gene id: 455488:A2CP1_RS05320
uniprot id: B8JF62
names: Similarity
messages: Belongs to the YciI family.

455488:A2CP1 RS19510
gene id: 455488:A2CP1_RS19510
uniprot id: B8J7L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

455488:A2CP1 RS03720
gene id: 455488:A2CP1_RS03720
uniprot id: B8JD74
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS15335
gene id: 455488:A2CP1_RS15335
uniprot id: B8JFK0
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS12355
gene id: 455488:A2CP1_RS12355
uniprot id: B8JBG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS09915
gene id: 455488:A2CP1_RS09915
uniprot id: B8J817
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

455488:A2CP1 RS12140
gene id: 455488:A2CP1_RS12140
uniprot id: B8JBC1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS00335
gene id: 455488:A2CP1_RS00335
uniprot id: B8J7T2
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

455488:A2CP1 RS03585
gene id: 455488:A2CP1_RS03585
uniprot id: B8JD47
names: Similarity
messages: Belongs to the GSP E family.

455488:A2CP1 RS13350
gene id: 455488:A2CP1_RS13350
uniprot id: B8JDD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

455488:A2CP1 RS18030
gene id: 455488:A2CP1_RS18030
uniprot id: B8J612
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

455488:A2CP1 RS03405
gene id: 455488:A2CP1_RS03405
uniprot id: B8JD12
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

455488:A2CP1 RS13055
gene id: 455488:A2CP1_RS13055
uniprot id: B8JD79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

455488:A2CP1 RS02020
gene id: 455488:A2CP1_RS02020
uniprot id: B8JAV4
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00510
gene id: 455488:A2CP1_RS00510
uniprot id: B8J7W8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS20560
gene id: 455488:A2CP1_RS20560
uniprot id: B8J9L4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

455488:A2CP1 RS19695
gene id: 455488:A2CP1_RS19695
uniprot id: B8J8E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

455488:A2CP1 RS19725
gene id: 455488:A2CP1_RS19725
uniprot id: B8J8F1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

455488:A2CP1 RS03140
gene id: 455488:A2CP1_RS03140
uniprot id: B8JCV8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

455488:A2CP1 RS03825
gene id: 455488:A2CP1_RS03825
uniprot id: B8JDM6
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

455488:A2CP1 RS01250
gene id: 455488:A2CP1_RS01250
uniprot id: B8J913
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS20140
gene id: 455488:A2CP1_RS20140
uniprot id: B8J8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

455488:A2CP1 RS02535
gene id: 455488:A2CP1_RS02535
uniprot id: B8JB55
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

455488:A2CP1 RS00295
gene id: 455488:A2CP1_RS00295
uniprot id: B8J7S5
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

455488:A2CP1 RS10240
gene id: 455488:A2CP1_RS10240
uniprot id: B8J881
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS11545
gene id: 455488:A2CP1_RS11545
uniprot id: B8JAB6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

455488:A2CP1 RS14640
gene id: 455488:A2CP1_RS14640
uniprot id: B8JEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS02520
gene id: 455488:A2CP1_RS02520
uniprot id: B8JB52
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

455488:A2CP1 RS06915
gene id: 455488:A2CP1_RS06915
uniprot id: B8JH18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS10115
gene id: 455488:A2CP1_RS10115
uniprot id: B8J856
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

455488:A2CP1 RS09165
gene id: 455488:A2CP1_RS09165
uniprot id: B8J6I8
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

455488:A2CP1 RS02030
gene id: 455488:A2CP1_RS02030
uniprot id: B8JAV6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS10145
gene id: 455488:A2CP1_RS10145
uniprot id: B8J862
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

455488:A2CP1 RS20100
gene id: 455488:A2CP1_RS20100
uniprot id: B8J8M5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

455488:A2CP1 RS12530
gene id: 455488:A2CP1_RS12530
uniprot id: B8JC85
names: Similarity
messages: Belongs to the YciI family.

455488:A2CP1 RS18660
gene id: 455488:A2CP1_RS18660
uniprot id: B8J6Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

455488:A2CP1 RS10040
gene id: 455488:A2CP1_RS10040
uniprot id: B8J841
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

455488:A2CP1 RS13180
gene id: 455488:A2CP1_RS13180
uniprot id: B8JDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

455488:A2CP1 RS01320
gene id: 455488:A2CP1_RS01320
uniprot id: B8J927
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS04180
gene id: 455488:A2CP1_RS04180
uniprot id: B8JDU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

455488:A2CP1 RS19780
gene id: 455488:A2CP1_RS19780
uniprot id: B8J8G2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

455488:A2CP1 RS00825
gene id: 455488:A2CP1_RS00825
uniprot id: B8J8S5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

455488:A2CP1 RS20575
gene id: 455488:A2CP1_RS20575
uniprot id: B8J9L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

455488:A2CP1 RS01595
gene id: 455488:A2CP1_RS01595
uniprot id: B8J9X7
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS13915
gene id: 455488:A2CP1_RS13915
uniprot id: B8JE36
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

455488:A2CP1 RS09225
gene id: 455488:A2CP1_RS09225
uniprot id: B8J6K0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

455488:A2CP1 RS14060
gene id: 455488:A2CP1_RS14060
uniprot id: B8JE60
names: Similarity
messages: Belongs to the YicC/YloC family.

455488:A2CP1 RS22580
gene id: 455488:A2CP1_RS22580
uniprot id: B8JCU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

455488:A2CP1 RS13730
gene id: 455488:A2CP1_RS13730
uniprot id: B8JDZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

455488:A2CP1 RS02055
gene id: 455488:A2CP1_RS02055
uniprot id: B8JAW1
names: Similarity
messages: Belongs to the peptidase S1C family.

455488:A2CP1 RS03735
gene id: 455488:A2CP1_RS03735
uniprot id: B8JDL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

455488:A2CP1 RS21905
gene id: 455488:A2CP1_RS21905
uniprot id: B8JBR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS19700
gene id: 455488:A2CP1_RS19700
uniprot id: B8J8E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

455488:A2CP1 RS08105
gene id: 455488:A2CP1_RS08105
uniprot id: B8J5L1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

455488:A2CP1 RS22300
gene id: 455488:A2CP1_RS22300
uniprot id: B8JCM9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

455488:A2CP1 RS13845
gene id: 455488:A2CP1_RS13845
uniprot id: B8JE21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

455488:A2CP1 RS12515
gene id: 455488:A2CP1_RS12515
uniprot id: B8JC83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

455488:A2CP1 RS09550
gene id: 455488:A2CP1_RS09550
uniprot id: B8J754
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

455488:A2CP1 RS19290
gene id: 455488:A2CP1_RS19290
uniprot id: B8J7H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

455488:A2CP1 RS21655
gene id: 455488:A2CP1_RS21655
uniprot id: B8JBL1
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

455488:A2CP1 RS01460
gene id: 455488:A2CP1_RS01460
uniprot id: B8J9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

455488:A2CP1 RS13595
gene id: 455488:A2CP1_RS13595
uniprot id: B8JDI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

455488:A2CP1 RS01985
gene id: 455488:A2CP1_RS01985
uniprot id: B8JAU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

455488:A2CP1 RS16215
gene id: 455488:A2CP1_RS16215
uniprot id: B8JGR7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

455488:A2CP1 RS12155
gene id: 455488:A2CP1_RS12155
uniprot id: B8JBC5
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

455488:A2CP1 RS19440
gene id: 455488:A2CP1_RS19440
uniprot id: B8J7K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

455488:A2CP1 RS10605
gene id: 455488:A2CP1_RS10605
uniprot id: B8J946
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00260
gene id: 455488:A2CP1_RS00260
uniprot id: B8J7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

455488:A2CP1 RS05425
gene id: 455488:A2CP1_RS05425
uniprot id: B8JF81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS11215
gene id: 455488:A2CP1_RS11215
uniprot id: B8JA50
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

455488:A2CP1 RS03580
gene id: 455488:A2CP1_RS03580
uniprot id: B8JD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

455488:A2CP1 RS08800
gene id: 455488:A2CP1_RS08800
uniprot id: B8J6B4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

455488:A2CP1 RS13665
gene id: 455488:A2CP1_RS13665
uniprot id: B8JDY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

455488:A2CP1 RS09480
gene id: 455488:A2CP1_RS09480
uniprot id: B8J740
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

455488:A2CP1 RS06310
gene id: 455488:A2CP1_RS06310
uniprot id: B8JGD5
names: Similarity
messages: Belongs to the CutA family.

455488:A2CP1 RS21835
gene id: 455488:A2CP1_RS21835
uniprot id: B8JBP7
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS06120
gene id: 455488:A2CP1_RS06120
uniprot id: B8JFY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

455488:A2CP1 RS06795
gene id: 455488:A2CP1_RS06795
uniprot id: B8JGM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS09485
gene id: 455488:A2CP1_RS09485
uniprot id: B8J741
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

455488:A2CP1 RS01140
gene id: 455488:A2CP1_RS01140
uniprot id: B8J8Z1
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS01965
gene id: 455488:A2CP1_RS01965
uniprot id: B8JAU3
names: Similarity
messages: Belongs to the GbsR family.

455488:A2CP1 RS20600
gene id: 455488:A2CP1_RS20600
uniprot id: B8J9M2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

455488:A2CP1 RS02460
gene id: 455488:A2CP1_RS02460
uniprot id: B8JB40
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS05100
gene id: 455488:A2CP1_RS05100
uniprot id: B8JF19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS19155
gene id: 455488:A2CP1_RS19155
uniprot id: B8J7E5
names: Similarity
messages: Belongs to the FrhG family.

455488:A2CP1 RS15245
gene id: 455488:A2CP1_RS15245
uniprot id: B8JFI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

455488:A2CP1 RS00505
gene id: 455488:A2CP1_RS00505
uniprot id: B8J7W7
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS21505
gene id: 455488:A2CP1_RS21505
uniprot id: B8JBI1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

455488:A2CP1 RS22455
gene id: 455488:A2CP1_RS22455
uniprot id: B8JCR5
names: Similarity
messages: Belongs to the LarC family.

455488:A2CP1 RS10840
gene id: 455488:A2CP1_RS10840
uniprot id: B8J991
names: Similarity
messages: Belongs to the Nudix hydrolase family.

455488:A2CP1 RS14770
gene id: 455488:A2CP1_RS14770
uniprot id: B8JEW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

455488:A2CP1 RS02550
gene id: 455488:A2CP1_RS02550
uniprot id: B8JBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

455488:A2CP1 RS09300
gene id: 455488:A2CP1_RS09300
uniprot id: B8J6L3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS16635
gene id: 455488:A2CP1_RS16635
uniprot id: B8JH01
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

455488:A2CP1 RS04445
gene id: 455488:A2CP1_RS04445
uniprot id: B8JEC0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

455488:A2CP1 RS16190
gene id: 455488:A2CP1_RS16190
uniprot id: B8JGR3
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

455488:A2CP1 RS17685
gene id: 455488:A2CP1_RS17685
uniprot id: B8J5H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

455488:A2CP1 RS12325
gene id: 455488:A2CP1_RS12325
uniprot id: B8JBF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

455488:A2CP1 RS19365
gene id: 455488:A2CP1_RS19365
uniprot id: B8J7I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

455488:A2CP1 RS05985
gene id: 455488:A2CP1_RS05985
uniprot id: B8JFV5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

455488:A2CP1 RS06810
gene id: 455488:A2CP1_RS06810
uniprot id: B8JGM8
names: Similarity
messages: Belongs to the MEMO1 family.

455488:A2CP1 RS10210
gene id: 455488:A2CP1_RS10210
uniprot id: B8J875
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

455488:A2CP1 RS12185
gene id: 455488:A2CP1_RS12185
uniprot id: B8JBD1
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

455488:A2CP1 RS20540
gene id: 455488:A2CP1_RS20540
uniprot id: B8J9L0
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS13505
gene id: 455488:A2CP1_RS13505
uniprot id: B8JDG9
names: Subcellular Location Annotation
messages: Cytoplasm

455488:A2CP1 RS10120
gene id: 455488:A2CP1_RS10120
uniprot id: B8J857
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

455488:A2CP1 RS02590
gene id: 455488:A2CP1_RS02590
uniprot id: B8JBV5
names: Similarity
messages: Belongs to the hemerythrin family.

455488:A2CP1 RS01495
gene id: 455488:A2CP1_RS01495
uniprot id: B8J9V7
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

455488:A2CP1 RS09365
gene id: 455488:A2CP1_RS09365
uniprot id: B8J718
names: Similarity
messages: Belongs to the FPG family.

455488:A2CP1 RS15860
gene id: 455488:A2CP1_RS15860
uniprot id: B8JG81
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

455488:A2CP1 RS00950
gene id: 455488:A2CP1_RS00950
uniprot id: B8J8V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

455488:A2CP1 RS15955
gene id: 455488:A2CP1_RS15955
uniprot id: B8JGA1
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS22415
gene id: 455488:A2CP1_RS22415
uniprot id: B8JCQ7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

455488:A2CP1 RS12210
gene id: 455488:A2CP1_RS12210
uniprot id: B8JBD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS04700
gene id: 455488:A2CP1_RS04700
uniprot id: B8JEH0
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS18820
gene id: 455488:A2CP1_RS18820
uniprot id: B8J6T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

455488:A2CP1 RS22795
gene id: 455488:A2CP1_RS22795
uniprot id: B8JGH7
names: Similarity
messages: Belongs to the peptidase S14 family.

455488:A2CP1 RS03250
gene id: 455488:A2CP1_RS03250
uniprot id: B8JCY1
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

455488:A2CP1 RS07185
gene id: 455488:A2CP1_RS07185
uniprot id: B8JH73
names: Similarity
messages: Belongs to the Dps family.

455488:A2CP1 RS10015
gene id: 455488:A2CP1_RS10015
uniprot id: B8J836
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

455488:A2CP1 RS09670
gene id: 455488:A2CP1_RS09670
uniprot id: B8J778
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

455488:A2CP1 RS14015
gene id: 455488:A2CP1_RS14015
uniprot id: B8JE56
names: Similarity
messages: Belongs to the Nudix hydrolase family.

455488:A2CP1 RS14270
gene id: 455488:A2CP1_RS14270
uniprot id: B8JEA3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS20775
gene id: 455488:A2CP1_RS20775
uniprot id: B8J9Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

455488:A2CP1 RS13125
gene id: 455488:A2CP1_RS13125
uniprot id: B8JD93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

455488:A2CP1 RS11670
gene id: 455488:A2CP1_RS11670
uniprot id: B8JAE1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

455488:A2CP1 RS11140
gene id: 455488:A2CP1_RS11140
uniprot id: B8J9E8
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

455488:A2CP1 RS10125
gene id: 455488:A2CP1_RS10125
uniprot id: B8J858
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

455488:A2CP1 RS03635
gene id: 455488:A2CP1_RS03635
uniprot id: B8JD57
names: Similarity
messages: Belongs to the acylphosphatase family.

455488:A2CP1 RS16710
gene id: 455488:A2CP1_RS16710
uniprot id: B8JHE1
names: Similarity
messages: Belongs to the YciI family.

455488:A2CP1 RS04035
gene id: 455488:A2CP1_RS04035
uniprot id: B8JDR9
names: Similarity
messages: Belongs to the universal stress protein A family.

455488:A2CP1 RS12615
gene id: 455488:A2CP1_RS12615
uniprot id: B8JCA2
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS03105
gene id: 455488:A2CP1_RS03105
uniprot id: B8JC57
names: Similarity
messages: Belongs to the heat shock protein 70 family.

455488:A2CP1 RS17725
gene id: 455488:A2CP1_RS17725
uniprot id: B8J5I3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS04980
gene id: 455488:A2CP1_RS04980
uniprot id: B8JEZ4
names: Function
names: Similarity
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.

455488:A2CP1 RS15160
gene id: 455488:A2CP1_RS15160
uniprot id: B8JFG5
names: Similarity
messages: Belongs to the bacterial secretin family.

455488:A2CP1 RS19030
gene id: 455488:A2CP1_RS19030
uniprot id: B8J6Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

455488:A2CP1 RS19930
gene id: 455488:A2CP1_RS19930
uniprot id: B8J8J2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

455488:A2CP1 RS04625
gene id: 455488:A2CP1_RS04625
uniprot id: B8JEF6
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS07045
gene id: 455488:A2CP1_RS07045
uniprot id: B8JH44
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

455488:A2CP1 RS19320
gene id: 455488:A2CP1_RS19320
uniprot id: B8J7H8
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS19740
gene id: 455488:A2CP1_RS19740
uniprot id: B8J8F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

455488:A2CP1 RS20890
gene id: 455488:A2CP1_RS20890
uniprot id: B8J9S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

455488:A2CP1 RS08585
gene id: 455488:A2CP1_RS08585
uniprot id: B8J5V5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

455488:A2CP1 RS21430
gene id: 455488:A2CP1_RS21430
uniprot id: B8JAS5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

455488:A2CP1 RS14435
gene id: 455488:A2CP1_RS14435
uniprot id: B8JEQ3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

455488:A2CP1 RS20975
gene id: 455488:A2CP1_RS20975
uniprot id: B8JAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

455488:A2CP1 RS08875
gene id: 455488:A2CP1_RS08875
uniprot id: B8J6C9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS21120
gene id: 455488:A2CP1_RS21120
uniprot id: B8JAL2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

455488:A2CP1 RS06330
gene id: 455488:A2CP1_RS06330
uniprot id: B8JGD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS16150
gene id: 455488:A2CP1_RS16150
uniprot id: B8JGQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

455488:A2CP1 RS20000
gene id: 455488:A2CP1_RS20000
uniprot id: B8J8K5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

455488:A2CP1 RS11815
gene id: 455488:A2CP1_RS11815
uniprot id: B8JB62
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

455488:A2CP1 RS07700
gene id: 455488:A2CP1_RS07700
uniprot id: B8J522
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS13715
gene id: 455488:A2CP1_RS13715
uniprot id: B8JDZ6
names: Subcellular Location Annotation
messages: Cytoplasm

455488:A2CP1 RS14220
gene id: 455488:A2CP1_RS14220
uniprot id: B8JE93
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS09395
gene id: 455488:A2CP1_RS09395
uniprot id: B8J723
names: Subcellular Location Annotation
messages: Cytoplasm

455488:A2CP1 RS05165
gene id: 455488:A2CP1_RS05165
uniprot id: B8JF32
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS22435
gene id: 455488:A2CP1_RS22435
uniprot id: B8JCR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

455488:A2CP1 RS02570
gene id: 455488:A2CP1_RS02570
uniprot id: B8JBV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

455488:A2CP1 RS11555
gene id: 455488:A2CP1_RS11555
uniprot id: B8JAB8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

455488:A2CP1 RS09265
gene id: 455488:A2CP1_RS09265
uniprot id: B8J6K6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

455488:A2CP1 RS00300
gene id: 455488:A2CP1_RS00300
uniprot id: B8J7S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

455488:A2CP1 RS11860
gene id: 455488:A2CP1_RS11860
uniprot id: B8JB71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

455488:A2CP1 RS21725
gene id: 455488:A2CP1_RS21725
uniprot id: B8JBM5
names: Similarity
messages: Belongs to the HdrA family.

455488:A2CP1 RS17785
gene id: 455488:A2CP1_RS17785
uniprot id: B8J5J5
names: Similarity
messages: Belongs to the GST superfamily.

455488:A2CP1 RS13590
gene id: 455488:A2CP1_RS13590
uniprot id: B8JDI6
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

455488:A2CP1 RS08160
gene id: 455488:A2CP1_RS08160
uniprot id: B8J5M2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

455488:A2CP1 RS14790
gene id: 455488:A2CP1_RS14790
uniprot id: B8JEX2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

455488:A2CP1 RS02325
gene id: 455488:A2CP1_RS02325
uniprot id: B8JB15
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS15645
gene id: 455488:A2CP1_RS15645
uniprot id: B8JG37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

455488:A2CP1 RS20655
gene id: 455488:A2CP1_RS20655
uniprot id: B8J9N3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

455488:A2CP1 RS02910
gene id: 455488:A2CP1_RS02910
uniprot id: B8JC21
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS03590
gene id: 455488:A2CP1_RS03590
uniprot id: B8JD48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

455488:A2CP1 RS06160
gene id: 455488:A2CP1_RS06160
uniprot id: B8JFY9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

455488:A2CP1 RS13460
gene id: 455488:A2CP1_RS13460
uniprot id: B8JDG0
names: Similarity
messages: Belongs to the GSP E family.

455488:A2CP1 RS06665
gene id: 455488:A2CP1_RS06665
uniprot id: B8JGK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

455488:A2CP1 RS18115
gene id: 455488:A2CP1_RS18115
uniprot id: B8J629
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS19230
gene id: 455488:A2CP1_RS19230
uniprot id: B8J7G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

455488:A2CP1 RS02060
gene id: 455488:A2CP1_RS02060
uniprot id: B8JAW2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

455488:A2CP1 RS10090
gene id: 455488:A2CP1_RS10090
uniprot id: B8J851
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

455488:A2CP1 RS08065
gene id: 455488:A2CP1_RS08065
uniprot id: B8J595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

455488:A2CP1 RS14780
gene id: 455488:A2CP1_RS14780
uniprot id: B8JEX0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

455488:A2CP1 RS06925
gene id: 455488:A2CP1_RS06925
uniprot id: B8JH20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

455488:A2CP1 RS16925
gene id: 455488:A2CP1_RS16925
uniprot id: B8JHI4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS21240
gene id: 455488:A2CP1_RS21240
uniprot id: B8JAN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

455488:A2CP1 RS07340
gene id: 455488:A2CP1_RS07340
uniprot id: B8JHA3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

455488:A2CP1 RS02165
gene id: 455488:A2CP1_RS02165
uniprot id: B8JAY3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

455488:A2CP1 RS05450
gene id: 455488:A2CP1_RS05450
uniprot id: B8JF86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS15580
gene id: 455488:A2CP1_RS15580
uniprot id: B8JG24
names: Similarity
messages: Belongs to the cytochrome c-552 family.

455488:A2CP1 RS01275
gene id: 455488:A2CP1_RS01275
uniprot id: B8J918
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

455488:A2CP1 RS20080
gene id: 455488:A2CP1_RS20080
uniprot id: B8J8M1
names: Similarity
messages: Belongs to the peptidase U62 family.

455488:A2CP1 RS19940
gene id: 455488:A2CP1_RS19940
uniprot id: B8J8J4
names: Similarity
messages: Belongs to the AHA1 family.

455488:A2CP1 RS13920
gene id: 455488:A2CP1_RS13920
uniprot id: B8JE37
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

455488:A2CP1 RS13495
gene id: 455488:A2CP1_RS13495
uniprot id: B8JDG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

455488:A2CP1 RS07815
gene id: 455488:A2CP1_RS07815
uniprot id: B8J545
names: Subcellular Location Annotation
messages: Periplasm

455488:A2CP1 RS08030
gene id: 455488:A2CP1_RS08030
uniprot id: B8J588
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS04240
gene id: 455488:A2CP1_RS04240
uniprot id: B8JDW1
names: Similarity
messages: Belongs to the SCO1/2 family.

455488:A2CP1 RS12425
gene id: 455488:A2CP1_RS12425
uniprot id: B8JC65
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

455488:A2CP1 RS17615
gene id: 455488:A2CP1_RS17615
uniprot id: B8J5G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

455488:A2CP1 RS11100
gene id: 455488:A2CP1_RS11100
uniprot id: B8J9E0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS04880
gene id: 455488:A2CP1_RS04880
uniprot id: B8JEK5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

455488:A2CP1 RS20895
gene id: 455488:A2CP1_RS20895
uniprot id: B8JAG6
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

455488:A2CP1 RS19385
gene id: 455488:A2CP1_RS19385
uniprot id: B8J7J1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

455488:A2CP1 RS07840
gene id: 455488:A2CP1_RS07840
uniprot id: B8J550
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS01950
gene id: 455488:A2CP1_RS01950
uniprot id: B8JAU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

455488:A2CP1 RS04540
gene id: 455488:A2CP1_RS04540
uniprot id: B8JED9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

455488:A2CP1 RS00360
gene id: 455488:A2CP1_RS00360
uniprot id: B8J7T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

455488:A2CP1 RS16900
gene id: 455488:A2CP1_RS16900
uniprot id: B8JHH9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

455488:A2CP1 RS10255
gene id: 455488:A2CP1_RS10255
uniprot id: B8J884
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

455488:A2CP1 RS13280
gene id: 455488:A2CP1_RS13280
uniprot id: B8JDC4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

455488:A2CP1 RS06920
gene id: 455488:A2CP1_RS06920
uniprot id: B8JH19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS08860
gene id: 455488:A2CP1_RS08860
uniprot id: B8J6C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

455488:A2CP1 RS06940
gene id: 455488:A2CP1_RS06940
uniprot id: B8JH23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS03325
gene id: 455488:A2CP1_RS03325
uniprot id: B8JCZ6
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS21140
gene id: 455488:A2CP1_RS21140
uniprot id: B8JAL6
names: Similarity
messages: Belongs to the TrpC family.

455488:A2CP1 RS14550
gene id: 455488:A2CP1_RS14550
uniprot id: B8JES6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

455488:A2CP1 RS21840
gene id: 455488:A2CP1_RS21840
uniprot id: B8JBP8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

455488:A2CP1 RS09470
gene id: 455488:A2CP1_RS09470
uniprot id: B8J738
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS10385
gene id: 455488:A2CP1_RS10385
uniprot id: B8J8B0
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

455488:A2CP1 RS05605
gene id: 455488:A2CP1_RS05605
uniprot id: B8JFB0
names: Similarity
messages: Belongs to the UPF0758 family.

455488:A2CP1 RS22695
gene id: 455488:A2CP1_RS22695
uniprot id: B8JDK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

455488:A2CP1 RS00865
gene id: 455488:A2CP1_RS00865
uniprot id: B8J8T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

455488:A2CP1 RS18800
gene id: 455488:A2CP1_RS18800
uniprot id: B8J6T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

455488:A2CP1 RS10595
gene id: 455488:A2CP1_RS10595
uniprot id: B8J944
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Belongs to the Nudix hydrolase family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

455488:A2CP1 RS10560
gene id: 455488:A2CP1_RS10560
uniprot id: B8J937
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

455488:A2CP1 RS14580
gene id: 455488:A2CP1_RS14580
uniprot id: B8JET2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS10245
gene id: 455488:A2CP1_RS10245
uniprot id: B8J882
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

455488:A2CP1 RS13885
gene id: 455488:A2CP1_RS13885
uniprot id: B8JE30
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

455488:A2CP1 RS22685
gene id: 455488:A2CP1_RS22685
uniprot id: B8JDK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

455488:A2CP1 RS09645
gene id: 455488:A2CP1_RS09645
uniprot id: B8J773
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS13755
gene id: 455488:A2CP1_RS13755
uniprot id: B8JE04
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS03085
gene id: 455488:A2CP1_RS03085
uniprot id: B8JC53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

455488:A2CP1 RS08745
gene id: 455488:A2CP1_RS08745
uniprot id: B8J6A3
names: Similarity
messages: Belongs to the pirin family.

455488:A2CP1 RS13215
gene id: 455488:A2CP1_RS13215
uniprot id: B8JDB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

455488:A2CP1 RS22490
gene id: 455488:A2CP1_RS22490
uniprot id: B8JCS2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

455488:A2CP1 RS04970
gene id: 455488:A2CP1_RS04970
uniprot id: B8JEZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

455488:A2CP1 RS02605
gene id: 455488:A2CP1_RS02605
uniprot id: B8JBV8
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS06045
gene id: 455488:A2CP1_RS06045
uniprot id: B8JFW6
names: Similarity
messages: Belongs to the Skp family.

455488:A2CP1 RS18055
gene id: 455488:A2CP1_RS18055
uniprot id: B8J617
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

455488:A2CP1 RS08100
gene id: 455488:A2CP1_RS08100
uniprot id: B8J5L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS14810
gene id: 455488:A2CP1_RS14810
uniprot id: B8JEX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

455488:A2CP1 RS16235
gene id: 455488:A2CP1_RS16235
uniprot id: B8JGS0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

455488:A2CP1 RS00500
gene id: 455488:A2CP1_RS00500
uniprot id: B8J7W6
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS14440
gene id: 455488:A2CP1_RS14440
uniprot id: B8JEQ4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

455488:A2CP1 RS04245
gene id: 455488:A2CP1_RS04245
uniprot id: B8JDW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

455488:A2CP1 RS07780
gene id: 455488:A2CP1_RS07780
uniprot id: B8J538
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

455488:A2CP1 RS19820
gene id: 455488:A2CP1_RS19820
uniprot id: B8J8H0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

455488:A2CP1 RS00495
gene id: 455488:A2CP1_RS00495
uniprot id: B8J7W5
names: Similarity
messages: Belongs to the LEA type 2 family.

455488:A2CP1 RS13675
gene id: 455488:A2CP1_RS13675
uniprot id: B8JDY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

455488:A2CP1 RS12465
gene id: 455488:A2CP1_RS12465
uniprot id: B8JC73
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

455488:A2CP1 RS20010
gene id: 455488:A2CP1_RS20010
uniprot id: B8J8K7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

455488:A2CP1 RS06935
gene id: 455488:A2CP1_RS06935
uniprot id: B8JH22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS18455
gene id: 455488:A2CP1_RS18455
uniprot id: B8J6L9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS00245
gene id: 455488:A2CP1_RS00245
uniprot id: B8J7R4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

455488:A2CP1 RS22075
gene id: 455488:A2CP1_RS22075
uniprot id: B8JBU6
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

455488:A2CP1 RS21625
gene id: 455488:A2CP1_RS21625
uniprot id: B8JBK5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS13175
gene id: 455488:A2CP1_RS13175
uniprot id: B8JDA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

455488:A2CP1 RS11605
gene id: 455488:A2CP1_RS11605
uniprot id: B8JAC8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

455488:A2CP1 RS19810
gene id: 455488:A2CP1_RS19810
uniprot id: B8J8G8
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS12390
gene id: 455488:A2CP1_RS12390
uniprot id: B8JBH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

455488:A2CP1 RS21480
gene id: 455488:A2CP1_RS21480
uniprot id: B8JBH6
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

455488:A2CP1 RS01355
gene id: 455488:A2CP1_RS01355
uniprot id: B8J9S9
names: Subcellular Location Annotation
messages: Cytoplasm

455488:A2CP1 RS09885
gene id: 455488:A2CP1_RS09885
uniprot id: B8J7C1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

455488:A2CP1 RS22645
gene id: 455488:A2CP1_RS22645
uniprot id: B8JCV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

455488:A2CP1 RS00850
gene id: 455488:A2CP1_RS00850
uniprot id: B8J8T0
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00830
gene id: 455488:A2CP1_RS00830
uniprot id: B8J8S6
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

455488:A2CP1 RS01035
gene id: 455488:A2CP1_RS01035
uniprot id: B8J8W9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

455488:A2CP1 RS00515
gene id: 455488:A2CP1_RS00515
uniprot id: B8J7W9
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

455488:A2CP1 RS03655
gene id: 455488:A2CP1_RS03655
uniprot id: B8JD61
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

455488:A2CP1 RS09350
gene id: 455488:A2CP1_RS09350
uniprot id: B8J715
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

455488:A2CP1 RS13910
gene id: 455488:A2CP1_RS13910
uniprot id: B8JE35
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

455488:A2CP1 RS14165
gene id: 455488:A2CP1_RS14165
uniprot id: B8JE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS13080
gene id: 455488:A2CP1_RS13080
uniprot id: B8JD84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

455488:A2CP1 RS12865
gene id: 455488:A2CP1_RS12865
uniprot id: B8JCF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

455488:A2CP1 RS07285
gene id: 455488:A2CP1_RS07285
uniprot id: B8JH92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

455488:A2CP1 RS06115
gene id: 455488:A2CP1_RS06115
uniprot id: B8JFY0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

455488:A2CP1 RS06705
gene id: 455488:A2CP1_RS06705
uniprot id: B8JGL4
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

455488:A2CP1 RS05385
gene id: 455488:A2CP1_RS05385
uniprot id: B8JF74
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

455488:A2CP1 RS03385
gene id: 455488:A2CP1_RS03385
uniprot id: B8JD08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

455488:A2CP1 RS17310
gene id: 455488:A2CP1_RS17310
uniprot id: B8J5A6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

455488:A2CP1 RS00760
gene id: 455488:A2CP1_RS00760
uniprot id: B8J8R2
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS06055
gene id: 455488:A2CP1_RS06055
uniprot id: B8JFW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

455488:A2CP1 RS18815
gene id: 455488:A2CP1_RS18815
uniprot id: B8J6T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

455488:A2CP1 RS16205
gene id: 455488:A2CP1_RS16205
uniprot id: B8JGR5
names: Similarity
messages: Belongs to the hemerythrin family.

455488:A2CP1 RS22590
gene id: 455488:A2CP1_RS22590
uniprot id: B8JCU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

455488:A2CP1 RS04340
gene id: 455488:A2CP1_RS04340
uniprot id: B8JDY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

455488:A2CP1 RS16945
gene id: 455488:A2CP1_RS16945
uniprot id: B8JHI8
names: Subcellular Location Annotation
messages: Cytoplasm

455488:A2CP1 RS12950
gene id: 455488:A2CP1_RS12950
uniprot id: B8JCG7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

455488:A2CP1 RS21910
gene id: 455488:A2CP1_RS21910
uniprot id: B8JBR3
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

455488:A2CP1 RS08915
gene id: 455488:A2CP1_RS08915
uniprot id: B8J6D7
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS03835
gene id: 455488:A2CP1_RS03835
uniprot id: B8JDM8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

455488:A2CP1 RS05445
gene id: 455488:A2CP1_RS05445
uniprot id: B8JF85
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS04260
gene id: 455488:A2CP1_RS04260
uniprot id: B8JDW5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS12115
gene id: 455488:A2CP1_RS12115
uniprot id: B8JBB6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

455488:A2CP1 RS22270
gene id: 455488:A2CP1_RS22270
uniprot id: B8JCM3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS21380
gene id: 455488:A2CP1_RS21380
uniprot id: B8JAR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

455488:A2CP1 RS12690
gene id: 455488:A2CP1_RS12690
uniprot id: B8JCB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS00375
gene id: 455488:A2CP1_RS00375
uniprot id: B8J7U1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS10830
gene id: 455488:A2CP1_RS10830
uniprot id: B8J989
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS15305
gene id: 455488:A2CP1_RS15305
uniprot id: B8JFJ4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

455488:A2CP1 RS16785
gene id: 455488:A2CP1_RS16785
uniprot id: B8JHF6
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS04140
gene id: 455488:A2CP1_RS04140
uniprot id: B8JDU1
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

455488:A2CP1 RS00680
gene id: 455488:A2CP1_RS00680
uniprot id: B8J802
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

455488:A2CP1 RS18890
gene id: 455488:A2CP1_RS18890
uniprot id: B8J6V3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

455488:A2CP1 RS16580
gene id: 455488:A2CP1_RS16580
uniprot id: B8JGZ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

455488:A2CP1 RS01305
gene id: 455488:A2CP1_RS01305
uniprot id: B8J924
names: Similarity
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.

455488:A2CP1 RS02875
gene id: 455488:A2CP1_RS02875
uniprot id: B8JC14
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS20115
gene id: 455488:A2CP1_RS20115
uniprot id: B8J8M8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS15520
gene id: 455488:A2CP1_RS15520
uniprot id: B8JG12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS18495
gene id: 455488:A2CP1_RS18495
uniprot id: B8J6M7
names: Similarity
messages: Belongs to the CarB family.

455488:A2CP1 RS06240
gene id: 455488:A2CP1_RS06240
uniprot id: B8JGC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

455488:A2CP1 RS07130
gene id: 455488:A2CP1_RS07130
uniprot id: B8JH61
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

455488:A2CP1 RS20945
gene id: 455488:A2CP1_RS20945
uniprot id: B8JAH7
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS03760
gene id: 455488:A2CP1_RS03760
uniprot id: B8JDL4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

455488:A2CP1 RS11085
gene id: 455488:A2CP1_RS11085
uniprot id: B8J9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

455488:A2CP1 RS15340
gene id: 455488:A2CP1_RS15340
uniprot id: B8JFK1
names: Similarity
messages: Belongs to the peptidase A31 family.

455488:A2CP1 RS14920
gene id: 455488:A2CP1_RS14920
uniprot id: B8JFB6
names: Similarity
messages: Belongs to the asparagine synthetase family.

455488:A2CP1 RS04175
gene id: 455488:A2CP1_RS04175
uniprot id: B8JDU8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

455488:A2CP1 RS04190
gene id: 455488:A2CP1_RS04190
uniprot id: B8JDV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

455488:A2CP1 RS00395
gene id: 455488:A2CP1_RS00395
uniprot id: B8J7U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

455488:A2CP1 RS20590
gene id: 455488:A2CP1_RS20590
uniprot id: B8J9M0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS00390
gene id: 455488:A2CP1_RS00390
uniprot id: B8J7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

455488:A2CP1 RS07845
gene id: 455488:A2CP1_RS07845
uniprot id: B8J551
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS08710
gene id: 455488:A2CP1_RS08710
uniprot id: B8J696
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS08255
gene id: 455488:A2CP1_RS08255
uniprot id: B8J5N9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

455488:A2CP1 RS16355
gene id: 455488:A2CP1_RS16355
uniprot id: B8JGU5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

455488:A2CP1 RS06060
gene id: 455488:A2CP1_RS06060
uniprot id: B8JFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

455488:A2CP1 RS13990
gene id: 455488:A2CP1_RS13990
uniprot id: B8JE51
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS06345
gene id: 455488:A2CP1_RS06345
uniprot id: B8JGE2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

455488:A2CP1 RS08890
gene id: 455488:A2CP1_RS08890
uniprot id: B8J6D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS09385
gene id: 455488:A2CP1_RS09385
uniprot id: B8J721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

455488:A2CP1 RS12380
gene id: 455488:A2CP1_RS12380
uniprot id: B8JBG9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

455488:A2CP1 RS21675
gene id: 455488:A2CP1_RS21675
uniprot id: B8JBL5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

455488:A2CP1 RS09950
gene id: 455488:A2CP1_RS09950
uniprot id: B8J823
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS12365
gene id: 455488:A2CP1_RS12365
uniprot id: B8JBG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

455488:A2CP1 RS10220
gene id: 455488:A2CP1_RS10220
uniprot id: B8J877
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

455488:A2CP1 RS02375
gene id: 455488:A2CP1_RS02375
uniprot id: B8JB24
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.

455488:A2CP1 RS12305
gene id: 455488:A2CP1_RS12305
uniprot id: B8JBF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

455488:A2CP1 RS05180
gene id: 455488:A2CP1_RS05180
uniprot id: B8JF35
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

455488:A2CP1 RS15175
gene id: 455488:A2CP1_RS15175
uniprot id: B8JFG8
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS09700
gene id: 455488:A2CP1_RS09700
uniprot id: B8J784
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS03110
gene id: 455488:A2CP1_RS03110
uniprot id: B8JC58
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

455488:A2CP1 RS12930
gene id: 455488:A2CP1_RS12930
uniprot id: B8JCG3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

455488:A2CP1 RS20770
gene id: 455488:A2CP1_RS20770
uniprot id: B8J9Q5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS03480
gene id: 455488:A2CP1_RS03480
uniprot id: B8JD26
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

455488:A2CP1 RS04500
gene id: 455488:A2CP1_RS04500
uniprot id: B8JED1
names: Similarity
messages: Belongs to the peptidase S1C family.

455488:A2CP1 RS03270
gene id: 455488:A2CP1_RS03270
uniprot id: B8JCY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

455488:A2CP1 RS19980
gene id: 455488:A2CP1_RS19980
uniprot id: B8J8K1
names: Similarity
messages: Belongs to the peptidase C69 family.

455488:A2CP1 RS02730
gene id: 455488:A2CP1_RS02730
uniprot id: B8JBY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

455488:A2CP1 RS05030
gene id: 455488:A2CP1_RS05030
uniprot id: B8JF04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

455488:A2CP1 RS20370
gene id: 455488:A2CP1_RS20370
uniprot id: B8J9H5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS01890
gene id: 455488:A2CP1_RS01890
uniprot id: B8JA37
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

455488:A2CP1 RS16055
gene id: 455488:A2CP1_RS16055
uniprot id: B8JGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

455488:A2CP1 RS06340
gene id: 455488:A2CP1_RS06340
uniprot id: B8JGE1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS14625
gene id: 455488:A2CP1_RS14625
uniprot id: B8JEU0
names: Similarity
messages: Belongs to the GSP E family.

455488:A2CP1 RS03495
gene id: 455488:A2CP1_RS03495
uniprot id: B8JD29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

455488:A2CP1 RS10295
gene id: 455488:A2CP1_RS10295
uniprot id: B8J892
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

455488:A2CP1 RS03555
gene id: 455488:A2CP1_RS03555
uniprot id: B8JD41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS21690
gene id: 455488:A2CP1_RS21690
uniprot id: B8JBL8
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS10845
gene id: 455488:A2CP1_RS10845
uniprot id: B8J992
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

455488:A2CP1 RS02715
gene id: 455488:A2CP1_RS02715
uniprot id: B8JBY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS11465
gene id: 455488:A2CP1_RS11465
uniprot id: B8JAA0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

455488:A2CP1 RS12485
gene id: 455488:A2CP1_RS12485
uniprot id: B8JC77
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

455488:A2CP1 RS10205
gene id: 455488:A2CP1_RS10205
uniprot id: B8J874
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

455488:A2CP1 RS02200
gene id: 455488:A2CP1_RS02200
uniprot id: B8JAZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS11730
gene id: 455488:A2CP1_RS11730
uniprot id: B8JAF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

455488:A2CP1 RS09975
gene id: 455488:A2CP1_RS09975
uniprot id: B8J828
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

455488:A2CP1 RS21135
gene id: 455488:A2CP1_RS21135
uniprot id: B8JAL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

455488:A2CP1 RS00020
gene id: 455488:A2CP1_RS00020
uniprot id: B8J6Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

455488:A2CP1 RS12925
gene id: 455488:A2CP1_RS12925
uniprot id: B8JCG2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

455488:A2CP1 RS09275
gene id: 455488:A2CP1_RS09275
uniprot id: B8J6K8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

455488:A2CP1 RS13355
gene id: 455488:A2CP1_RS13355
uniprot id: B8JDD9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

455488:A2CP1 RS00370
gene id: 455488:A2CP1_RS00370
uniprot id: B8J7U0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

455488:A2CP1 RS07665
gene id: 455488:A2CP1_RS07665
uniprot id: B8J515
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

455488:A2CP1 RS08500
gene id: 455488:A2CP1_RS08500
uniprot id: B8J5T9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS19135
gene id: 455488:A2CP1_RS19135
uniprot id: B8J7E1
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00380
gene id: 455488:A2CP1_RS00380
uniprot id: B8J7U2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS19795
gene id: 455488:A2CP1_RS19795
uniprot id: B8J8G5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS05285
gene id: 455488:A2CP1_RS05285
uniprot id: B8JF55
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

455488:A2CP1 RS07505
gene id: 455488:A2CP1_RS07505
uniprot id: B8J4Y3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

455488:A2CP1 RS03660
gene id: 455488:A2CP1_RS03660
uniprot id: B8JD62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

455488:A2CP1 RS04380
gene id: 455488:A2CP1_RS04380
uniprot id: B8JEA7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

455488:A2CP1 RS14805
gene id: 455488:A2CP1_RS14805
uniprot id: B8JEX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

455488:A2CP1 RS19400
gene id: 455488:A2CP1_RS19400
uniprot id: B8J7J4
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS12635
gene id: 455488:A2CP1_RS12635
uniprot id: B8JCA6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS18150
gene id: 455488:A2CP1_RS18150
uniprot id: B8J637
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

455488:A2CP1 RS00425
gene id: 455488:A2CP1_RS00425
uniprot id: B8J7V1
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

455488:A2CP1 RS18790
gene id: 455488:A2CP1_RS18790
uniprot id: B8J6T3
names: Similarity
messages: Belongs to the aspartokinase family.

455488:A2CP1 RS16830
gene id: 455488:A2CP1_RS16830
uniprot id: B8JHG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

455488:A2CP1 RS20565
gene id: 455488:A2CP1_RS20565
uniprot id: B8J9L5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

455488:A2CP1 RS06265
gene id: 455488:A2CP1_RS06265
uniprot id: B8JGC7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

455488:A2CP1 RS01955
gene id: 455488:A2CP1_RS01955
uniprot id: B8JAU1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

455488:A2CP1 RS08420
gene id: 455488:A2CP1_RS08420
uniprot id: B8J5S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

455488:A2CP1 RS09540
gene id: 455488:A2CP1_RS09540
uniprot id: B8J752
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS01730
gene id: 455488:A2CP1_RS01730
uniprot id: B8JA04
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

455488:A2CP1 RS05175
gene id: 455488:A2CP1_RS05175
uniprot id: B8JF34
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

455488:A2CP1 RS09100
gene id: 455488:A2CP1_RS09100
uniprot id: B8J6H5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS14570
gene id: 455488:A2CP1_RS14570
uniprot id: B8JET0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

455488:A2CP1 RS07615
gene id: 455488:A2CP1_RS07615
uniprot id: B8J505
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS21895
gene id: 455488:A2CP1_RS21895
uniprot id: B8JBR0
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS21815
gene id: 455488:A2CP1_RS21815
uniprot id: B8JBP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

455488:A2CP1 RS12190
gene id: 455488:A2CP1_RS12190
uniprot id: B8JBD2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

455488:A2CP1 RS11895
gene id: 455488:A2CP1_RS11895
uniprot id: B8JB77
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

455488:A2CP1 RS08365
gene id: 455488:A2CP1_RS08365
uniprot id: B8J5R2
names: PTM
messages: Binds 1 heme c group covalently per subunit.

455488:A2CP1 RS07025
gene id: 455488:A2CP1_RS07025
uniprot id: B8JH40
names: Similarity
messages: Belongs to the UPF0045 family.

455488:A2CP1 RS13435
gene id: 455488:A2CP1_RS13435
uniprot id: B8JDF5
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

455488:A2CP1 RS16200
gene id: 455488:A2CP1_RS16200
uniprot id: B8JGR4
names: Similarity
messages: Belongs to the hemerythrin family.

455488:A2CP1 RS20350
gene id: 455488:A2CP1_RS20350
uniprot id: B8J9H1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

455488:A2CP1 RS00490
gene id: 455488:A2CP1_RS00490
uniprot id: B8J7W4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

455488:A2CP1 RS11850
gene id: 455488:A2CP1_RS11850
uniprot id: B8JB69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

455488:A2CP1 RS03985
gene id: 455488:A2CP1_RS03985
uniprot id: B8JDQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS08170
gene id: 455488:A2CP1_RS08170
uniprot id: B8J5M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS08415
gene id: 455488:A2CP1_RS08415
uniprot id: B8J5S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

455488:A2CP1 RS03275
gene id: 455488:A2CP1_RS03275
uniprot id: B8JCY6
names: Similarity
messages: Belongs to the GSP E family.

455488:A2CP1 RS22125
gene id: 455488:A2CP1_RS22125
uniprot id: B8JCJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS00700
gene id: 455488:A2CP1_RS00700
uniprot id: B8J806
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

455488:A2CP1 RS18340
gene id: 455488:A2CP1_RS18340
uniprot id: B8J676
names: Similarity
messages: Belongs to the pirin family.

455488:A2CP1 RS17370
gene id: 455488:A2CP1_RS17370
uniprot id: B8J5B8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

455488:A2CP1 RS20455
gene id: 455488:A2CP1_RS20455
uniprot id: B8J9J2
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS19370
gene id: 455488:A2CP1_RS19370
uniprot id: B8J7I8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS21605
gene id: 455488:A2CP1_RS21605
uniprot id: B8JBK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

455488:A2CP1 RS22625
gene id: 455488:A2CP1_RS22625
uniprot id: B8JCU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

455488:A2CP1 RS09995
gene id: 455488:A2CP1_RS09995
uniprot id: B8J832
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

455488:A2CP1 RS20330
gene id: 455488:A2CP1_RS20330
uniprot id: B8J9G7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

455488:A2CP1 RS01870
gene id: 455488:A2CP1_RS01870
uniprot id: B8JA33
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS02415
gene id: 455488:A2CP1_RS02415
uniprot id: B8JB32
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

455488:A2CP1 RS21775
gene id: 455488:A2CP1_RS21775
uniprot id: B8JBN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

455488:A2CP1 RS05850
gene id: 455488:A2CP1_RS05850
uniprot id: B8JFS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS13310
gene id: 455488:A2CP1_RS13310
uniprot id: B8JDD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

455488:A2CP1 RS01030
gene id: 455488:A2CP1_RS01030
uniprot id: B8J8W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

455488:A2CP1 RS05375
gene id: 455488:A2CP1_RS05375
uniprot id: B8JF72
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

455488:A2CP1 RS20670
gene id: 455488:A2CP1_RS20670
uniprot id: B8J9N6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

455488:A2CP1 RS19865
gene id: 455488:A2CP1_RS19865
uniprot id: B8J8H9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

455488:A2CP1 RS15880
gene id: 455488:A2CP1_RS15880
uniprot id: B8JG86
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00585
gene id: 455488:A2CP1_RS00585
uniprot id: B8J7Y3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

455488:A2CP1 RS14815
gene id: 455488:A2CP1_RS14815
uniprot id: B8JEX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

455488:A2CP1 RS19205
gene id: 455488:A2CP1_RS19205
uniprot id: B8J7F5
names: Similarity
messages: Belongs to the citrate synthase family.

455488:A2CP1 RS03610
gene id: 455488:A2CP1_RS03610
uniprot id: B8JD52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

455488:A2CP1 RS17715
gene id: 455488:A2CP1_RS17715
uniprot id: B8J5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

455488:A2CP1 RS07470
gene id: 455488:A2CP1_RS07470
uniprot id: B8JHC9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

455488:A2CP1 RS14785
gene id: 455488:A2CP1_RS14785
uniprot id: B8JEX1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

455488:A2CP1 RS19125
gene id: 455488:A2CP1_RS19125
uniprot id: B8J7D9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS16495
gene id: 455488:A2CP1_RS16495
uniprot id: B8JGX3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

455488:A2CP1 RS01980
gene id: 455488:A2CP1_RS01980
uniprot id: B8JAU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

455488:A2CP1 RS18685
gene id: 455488:A2CP1_RS18685
uniprot id: B8J6R2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS04965
gene id: 455488:A2CP1_RS04965
uniprot id: B8JEM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

455488:A2CP1 RS19635
gene id: 455488:A2CP1_RS19635
uniprot id: B8J7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

455488:A2CP1 RS07085
gene id: 455488:A2CP1_RS07085
uniprot id: B8JH52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

455488:A2CP1 RS06955
gene id: 455488:A2CP1_RS06955
uniprot id: B8JH26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

455488:A2CP1 RS07435
gene id: 455488:A2CP1_RS07435
uniprot id: B8JHC2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

455488:A2CP1 RS17945
gene id: 455488:A2CP1_RS17945
uniprot id: B8J5Z5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS16910
gene id: 455488:A2CP1_RS16910
uniprot id: B8JHI1
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS07600
gene id: 455488:A2CP1_RS07600
uniprot id: B8J502
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

455488:A2CP1 RS03850
gene id: 455488:A2CP1_RS03850
uniprot id: B8JDN1
names: Similarity
messages: Belongs to the peptidase C40 family.

455488:A2CP1 RS09985
gene id: 455488:A2CP1_RS09985
uniprot id: B8J830
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

455488:A2CP1 RS11975
gene id: 455488:A2CP1_RS11975
uniprot id: B8JB89
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS20710
gene id: 455488:A2CP1_RS20710
uniprot id: B8J9P4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

455488:A2CP1 RS08510
gene id: 455488:A2CP1_RS08510
uniprot id: B8J5U1
names: Similarity
messages: Belongs to the peptidase S33 family.

455488:A2CP1 RS14750
gene id: 455488:A2CP1_RS14750
uniprot id: B8JEW4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

455488:A2CP1 RS09340
gene id: 455488:A2CP1_RS09340
uniprot id: B8J713
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

455488:A2CP1 RS07550
gene id: 455488:A2CP1_RS07550
uniprot id: B8J4Z2
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

455488:A2CP1 RS09710
gene id: 455488:A2CP1_RS09710
uniprot id: B8J786
names: Similarity
messages: Belongs to the phosphohexose mutase family.

455488:A2CP1 RS21035
gene id: 455488:A2CP1_RS21035
uniprot id: B8JAJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

455488:A2CP1 RS13875
gene id: 455488:A2CP1_RS13875
uniprot id: B8JE28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS10180
gene id: 455488:A2CP1_RS10180
uniprot id: B8J869
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

455488:A2CP1 RS18240
gene id: 455488:A2CP1_RS18240
uniprot id: B8J656
names: Similarity
messages: Belongs to the UDPGP type 2 family.

455488:A2CP1 RS10825
gene id: 455488:A2CP1_RS10825
uniprot id: B8J988
names: Cofactor
messages: Binds 1 zinc ion per subunit.

455488:A2CP1 RS12165
gene id: 455488:A2CP1_RS12165
uniprot id: B8JBC7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

455488:A2CP1 RS01500
gene id: 455488:A2CP1_RS01500
uniprot id: B8J9V8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS14240
gene id: 455488:A2CP1_RS14240
uniprot id: B8JE97
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

455488:A2CP1 RS13680
gene id: 455488:A2CP1_RS13680
uniprot id: B8JDY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

455488:A2CP1 RS13735
gene id: 455488:A2CP1_RS13735
uniprot id: B8JE00
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

455488:A2CP1 RS22345
gene id: 455488:A2CP1_RS22345
uniprot id: B8JCP2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

455488:A2CP1 RS00330
gene id: 455488:A2CP1_RS00330
uniprot id: B8J7T1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

455488:A2CP1 RS16270
gene id: 455488:A2CP1_RS16270
uniprot id: B8JGS8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

455488:A2CP1 RS01110
gene id: 455488:A2CP1_RS01110
uniprot id: B8J8Y5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS20535
gene id: 455488:A2CP1_RS20535
uniprot id: B8J9K9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00280
gene id: 455488:A2CP1_RS00280
uniprot id: B8J7S2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

455488:A2CP1 RS02720
gene id: 455488:A2CP1_RS02720
uniprot id: B8JBY2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

455488:A2CP1 RS00580
gene id: 455488:A2CP1_RS00580
uniprot id: B8J7Y2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

455488:A2CP1 RS14005
gene id: 455488:A2CP1_RS14005
uniprot id: B8JE54
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

455488:A2CP1 RS10320
gene id: 455488:A2CP1_RS10320
uniprot id: B8J897
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

455488:A2CP1 RS14925
gene id: 455488:A2CP1_RS14925
uniprot id: B8JFB7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS20085
gene id: 455488:A2CP1_RS20085
uniprot id: B8J8M2
names: Similarity
messages: Belongs to the peptidase U62 family.

455488:A2CP1 RS03965
gene id: 455488:A2CP1_RS03965
uniprot id: B8JDQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

455488:A2CP1 RS08425
gene id: 455488:A2CP1_RS08425
uniprot id: B8J5S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS19595
gene id: 455488:A2CP1_RS19595
uniprot id: B8J7N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

455488:A2CP1 RS03345
gene id: 455488:A2CP1_RS03345
uniprot id: B8JD00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

455488:A2CP1 RS21650
gene id: 455488:A2CP1_RS21650
uniprot id: B8JBL0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

455488:A2CP1 RS17530
gene id: 455488:A2CP1_RS17530
uniprot id: B8J5F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

455488:A2CP1 RS06975
gene id: 455488:A2CP1_RS06975
uniprot id: B8JH30
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS18490
gene id: 455488:A2CP1_RS18490
uniprot id: B8J6M6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS22690
gene id: 455488:A2CP1_RS22690
uniprot id: B8JDK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

455488:A2CP1 RS21770
gene id: 455488:A2CP1_RS21770
uniprot id: B8JBN4
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

455488:A2CP1 RS22220
gene id: 455488:A2CP1_RS22220
uniprot id: B8JCL3
names: Similarity
messages: Belongs to the leucine-binding protein family.

455488:A2CP1 RS04520
gene id: 455488:A2CP1_RS04520
uniprot id: B8JED5
names: Similarity
messages: Belongs to the SUI1 family.

455488:A2CP1 RS21930
gene id: 455488:A2CP1_RS21930
uniprot id: B8JBR7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

455488:A2CP1 RS17755
gene id: 455488:A2CP1_RS17755
uniprot id: B8J5I9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS11715
gene id: 455488:A2CP1_RS11715
uniprot id: B8JAF0
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

455488:A2CP1 RS01325
gene id: 455488:A2CP1_RS01325
uniprot id: B8J928
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

455488:A2CP1 RS12600
gene id: 455488:A2CP1_RS12600
uniprot id: B8JC99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

455488:A2CP1 RS05235
gene id: 455488:A2CP1_RS05235
uniprot id: B8JF46
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

455488:A2CP1 RS13655
gene id: 455488:A2CP1_RS13655
uniprot id: B8JDK0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS06030
gene id: 455488:A2CP1_RS06030
uniprot id: B8JFW3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS12995
gene id: 455488:A2CP1_RS12995
uniprot id: B8JCH6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS19685
gene id: 455488:A2CP1_RS19685
uniprot id: B8J8E3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS02825
gene id: 455488:A2CP1_RS02825
uniprot id: B8JC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

455488:A2CP1 RS13120
gene id: 455488:A2CP1_RS13120
uniprot id: B8JD92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

455488:A2CP1 RS18565
gene id: 455488:A2CP1_RS18565
uniprot id: B8J6P1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

455488:A2CP1 RS08765
gene id: 455488:A2CP1_RS08765
uniprot id: B8J6A7
names: Similarity
messages: Belongs to the thioredoxin family.

455488:A2CP1 RS16980
gene id: 455488:A2CP1_RS16980
uniprot id: B8JHJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

455488:A2CP1 RS12360
gene id: 455488:A2CP1_RS12360
uniprot id: B8JBG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

455488:A2CP1 RS03680
gene id: 455488:A2CP1_RS03680
uniprot id: B8JD66
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Membrane

455488:A2CP1 RS17995
gene id: 455488:A2CP1_RS17995
uniprot id: B8J605
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

455488:A2CP1 RS10270
gene id: 455488:A2CP1_RS10270
uniprot id: B8J887
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

455488:A2CP1 RS05845
gene id: 455488:A2CP1_RS05845
uniprot id: B8JFS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

455488:A2CP1 RS18770
gene id: 455488:A2CP1_RS18770
uniprot id: B8J6S9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

455488:A2CP1 RS02760
gene id: 455488:A2CP1_RS02760
uniprot id: B8JBZ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS14800
gene id: 455488:A2CP1_RS14800
uniprot id: B8JEX4
names: Similarity
messages: Belongs to the fabD family.

455488:A2CP1 RS14460
gene id: 455488:A2CP1_RS14460
uniprot id: B8JEQ8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

455488:A2CP1 RS20705
gene id: 455488:A2CP1_RS20705
uniprot id: B8J9P3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

455488:A2CP1 RS18590
gene id: 455488:A2CP1_RS18590
uniprot id: B8J502
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

455488:A2CP1 RS00445
gene id: 455488:A2CP1_RS00445
uniprot id: B8J7V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS09920
gene id: 455488:A2CP1_RS09920
uniprot id: B8J818
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS02280
gene id: 455488:A2CP1_RS02280
uniprot id: B8JB06
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

455488:A2CP1 RS06615
gene id: 455488:A2CP1_RS06615
uniprot id: B8JGJ5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS01370
gene id: 455488:A2CP1_RS01370
uniprot id: B8J9T2
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

455488:A2CP1 RS19505
gene id: 455488:A2CP1_RS19505
uniprot id: B8J7L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

455488:A2CP1 RS07310
gene id: 455488:A2CP1_RS07310
uniprot id: B8JH97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

455488:A2CP1 RS10185
gene id: 455488:A2CP1_RS10185
uniprot id: B8J870
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

455488:A2CP1 RS11110
gene id: 455488:A2CP1_RS11110
uniprot id: B8J9E2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

455488:A2CP1 RS09960
gene id: 455488:A2CP1_RS09960
uniprot id: B8J825
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

455488:A2CP1 RS13075
gene id: 455488:A2CP1_RS13075
uniprot id: B8JD83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

455488:A2CP1 RS14680
gene id: 455488:A2CP1_RS14680
uniprot id: B8JEV0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

455488:A2CP1 RS16655
gene id: 455488:A2CP1_RS16655
uniprot id: B8JH05
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS10225
gene id: 455488:A2CP1_RS10225
uniprot id: B8J878
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

455488:A2CP1 RS08640
gene id: 455488:A2CP1_RS08640
uniprot id: B8J5W6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

455488:A2CP1 RS10460
gene id: 455488:A2CP1_RS10460
uniprot id: B8J8C4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

455488:A2CP1 RS22575
gene id: 455488:A2CP1_RS22575
uniprot id: B8JCT9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

455488:A2CP1 RS06085
gene id: 455488:A2CP1_RS06085
uniprot id: B8JFX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

455488:A2CP1 RS02160
gene id: 455488:A2CP1_RS02160
uniprot id: B8JAY2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

455488:A2CP1 RS15555
gene id: 455488:A2CP1_RS15555
uniprot id: B8JG19
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

455488:A2CP1 RS02000
gene id: 455488:A2CP1_RS02000
uniprot id: B8JAV0
names: Similarity
messages: Belongs to the UbiD family.

455488:A2CP1 RS11400
gene id: 455488:A2CP1_RS11400
uniprot id: B8JA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS14690
gene id: 455488:A2CP1_RS14690
uniprot id: B8JEV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS07620
gene id: 455488:A2CP1_RS07620
uniprot id: B8J506
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

455488:A2CP1 RS07090
gene id: 455488:A2CP1_RS07090
uniprot id: B8JH53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

455488:A2CP1 RS03260
gene id: 455488:A2CP1_RS03260
uniprot id: B8JCY3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

455488:A2CP1 RS19705
gene id: 455488:A2CP1_RS19705
uniprot id: B8J8E7
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS03455
gene id: 455488:A2CP1_RS03455
uniprot id: B8JD21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

455488:A2CP1 RS04270
gene id: 455488:A2CP1_RS04270
uniprot id: B8JDW7
names: Similarity
messages: Belongs to the TPP enzyme family.

455488:A2CP1 RS16810
gene id: 455488:A2CP1_RS16810
uniprot id: B8JHG1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS14130
gene id: 455488:A2CP1_RS14130
uniprot id: B8JE75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS17775
gene id: 455488:A2CP1_RS17775
uniprot id: B8J5J3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS07480
gene id: 455488:A2CP1_RS07480
uniprot id: B8J4X8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

455488:A2CP1 RS18875
gene id: 455488:A2CP1_RS18875
uniprot id: B8J6V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

455488:A2CP1 RS08560
gene id: 455488:A2CP1_RS08560
uniprot id: B8J5V0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS06095
gene id: 455488:A2CP1_RS06095
uniprot id: B8JFX6
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

455488:A2CP1 RS04455
gene id: 455488:A2CP1_RS04455
uniprot id: B8JEC2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

455488:A2CP1 RS11055
gene id: 455488:A2CP1_RS11055
uniprot id: B8J9D1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

455488:A2CP1 RS20055
gene id: 455488:A2CP1_RS20055
uniprot id: B8J8L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

455488:A2CP1 RS11600
gene id: 455488:A2CP1_RS11600
uniprot id: B8JAC7
names: Similarity
messages: Belongs to the FBPase class 2 family.

455488:A2CP1 RS22210
gene id: 455488:A2CP1_RS22210
uniprot id: B8JCL1
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS10315
gene id: 455488:A2CP1_RS10315
uniprot id: B8J896
names: Similarity
messages: Belongs to the UPF0102 family.

455488:A2CP1 RS08110
gene id: 455488:A2CP1_RS08110
uniprot id: B8J5L2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

455488:A2CP1 RS02965
gene id: 455488:A2CP1_RS02965
uniprot id: B8JC30
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

455488:A2CP1 RS20800
gene id: 455488:A2CP1_RS20800
uniprot id: B8J9R1
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS18675
gene id: 455488:A2CP1_RS18675
uniprot id: B8J6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

455488:A2CP1 RS02190
gene id: 455488:A2CP1_RS02190
uniprot id: B8JAY8
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS21210
gene id: 455488:A2CP1_RS21210
uniprot id: B8JAN0
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

455488:A2CP1 RS16045
gene id: 455488:A2CP1_RS16045
uniprot id: B8JGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

455488:A2CP1 RS12885
gene id: 455488:A2CP1_RS12885
uniprot id: B8JCF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

455488:A2CP1 RS09625
gene id: 455488:A2CP1_RS09625
uniprot id: B8J769
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS02615
gene id: 455488:A2CP1_RS02615
uniprot id: B8JBW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

455488:A2CP1 RS14020
gene id: 455488:A2CP1_RS14020
uniprot id: B8JE57
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

455488:A2CP1 RS17740
gene id: 455488:A2CP1_RS17740
uniprot id: B8J5I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

455488:A2CP1 RS07490
gene id: 455488:A2CP1_RS07490
uniprot id: B8J4Y0
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS05220
gene id: 455488:A2CP1_RS05220
uniprot id: B8JF43
names: Subcellular Location Annotation
messages: Cytoplasm

455488:A2CP1 RS01085
gene id: 455488:A2CP1_RS01085
uniprot id: B8J8X9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

455488:A2CP1 RS14325
gene id: 455488:A2CP1_RS14325
uniprot id: B8JEN3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS07195
gene id: 455488:A2CP1_RS07195
uniprot id: B8JH75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

455488:A2CP1 RS09980
gene id: 455488:A2CP1_RS09980
uniprot id: B8J829
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

455488:A2CP1 RS03530
gene id: 455488:A2CP1_RS03530
uniprot id: B8JD36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

455488:A2CP1 RS08430
gene id: 455488:A2CP1_RS08430
uniprot id: B8J5S5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS14525
gene id: 455488:A2CP1_RS14525
uniprot id: B8JES1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

455488:A2CP1 RS14515
gene id: 455488:A2CP1_RS14515
uniprot id: B8JER9
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

455488:A2CP1 RS02565
gene id: 455488:A2CP1_RS02565
uniprot id: B8JBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

455488:A2CP1 RS18420
gene id: 455488:A2CP1_RS18420
uniprot id: B8J689
names: Similarity
messages: Belongs to the YciI family.

455488:A2CP1 RS12745
gene id: 455488:A2CP1_RS12745
uniprot id: B8JCC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

455488:A2CP1 RS14695
gene id: 455488:A2CP1_RS14695
uniprot id: B8JEV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS03675
gene id: 455488:A2CP1_RS03675
uniprot id: B8JD65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

455488:A2CP1 RS08115
gene id: 455488:A2CP1_RS08115
uniprot id: B8J5L3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

455488:A2CP1 RS22360
gene id: 455488:A2CP1_RS22360
uniprot id: B8JCP5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS03940
gene id: 455488:A2CP1_RS03940
uniprot id: B8JDQ0
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

455488:A2CP1 RS15940
gene id: 455488:A2CP1_RS15940
uniprot id: B8JG98
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS02455
gene id: 455488:A2CP1_RS02455
uniprot id: B8JB39
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS03630
gene id: 455488:A2CP1_RS03630
uniprot id: B8JD56
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

455488:A2CP1 RS11660
gene id: 455488:A2CP1_RS11660
uniprot id: B8JAD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

455488:A2CP1 RS05860
gene id: 455488:A2CP1_RS05860
uniprot id: B8JFT0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

455488:A2CP1 RS19630
gene id: 455488:A2CP1_RS19630
uniprot id: B8J7N8
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

455488:A2CP1 RS01875
gene id: 455488:A2CP1_RS01875
uniprot id: B8JA34
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

455488:A2CP1 RS11250
gene id: 455488:A2CP1_RS11250
uniprot id: B8JA57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

455488:A2CP1 RS08910
gene id: 455488:A2CP1_RS08910
uniprot id: B8J6D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS15530
gene id: 455488:A2CP1_RS15530
uniprot id: B8JG14
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS01960
gene id: 455488:A2CP1_RS01960
uniprot id: B8JAU2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

455488:A2CP1 RS08385
gene id: 455488:A2CP1_RS08385
uniprot id: B8J5R6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

455488:A2CP1 RS11360
gene id: 455488:A2CP1_RS11360
uniprot id: B8JA79
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

455488:A2CP1 RS08680
gene id: 455488:A2CP1_RS08680
uniprot id: B8J5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS12245
gene id: 455488:A2CP1_RS12245
uniprot id: B8JBE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS19265
gene id: 455488:A2CP1_RS19265
uniprot id: B8J7G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

455488:A2CP1 RS21145
gene id: 455488:A2CP1_RS21145
uniprot id: B8JAL7
names: Similarity
messages: Belongs to the TrpF family.

455488:A2CP1 RS22425
gene id: 455488:A2CP1_RS22425
uniprot id: B8JCQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

455488:A2CP1 RS07295
gene id: 455488:A2CP1_RS07295
uniprot id: B8JH94
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

455488:A2CP1 RS22525
gene id: 455488:A2CP1_RS22525
uniprot id: B8JCS9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

455488:A2CP1 RS07940
gene id: 455488:A2CP1_RS07940
uniprot id: B8J570
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS03400
gene id: 455488:A2CP1_RS03400
uniprot id: B8JD11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

455488:A2CP1 RS08930
gene id: 455488:A2CP1_RS08930
uniprot id: B8J6E0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

455488:A2CP1 RS03730
gene id: 455488:A2CP1_RS03730
uniprot id: B8JDK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

455488:A2CP1 RS13530
gene id: 455488:A2CP1_RS13530
uniprot id: B8JDH4
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS10360
gene id: 455488:A2CP1_RS10360
uniprot id: B8J8A5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

455488:A2CP1 RS03265
gene id: 455488:A2CP1_RS03265
uniprot id: B8JCY4
names: Similarity
messages: Belongs to the ribF family.

455488:A2CP1 RS16625
gene id: 455488:A2CP1_RS16625
uniprot id: B8JGZ9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

455488:A2CP1 RS00955
gene id: 455488:A2CP1_RS00955
uniprot id: B8J8V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

455488:A2CP1 RS11705
gene id: 455488:A2CP1_RS11705
uniprot id: B8JAE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

455488:A2CP1 RS13610
gene id: 455488:A2CP1_RS13610
uniprot id: B8JDJ1
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

455488:A2CP1 RS18740
gene id: 455488:A2CP1_RS18740
uniprot id: B8J6S3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

455488:A2CP1 RS06050
gene id: 455488:A2CP1_RS06050
uniprot id: B8JFW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

455488:A2CP1 RS13710
gene id: 455488:A2CP1_RS13710
uniprot id: B8JDZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

455488:A2CP1 RS08580
gene id: 455488:A2CP1_RS08580
uniprot id: B8J5V4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

455488:A2CP1 RS07095
gene id: 455488:A2CP1_RS07095
uniprot id: B8JH54
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

455488:A2CP1 RS17610
gene id: 455488:A2CP1_RS17610
uniprot id: B8J5G6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

455488:A2CP1 RS03100
gene id: 455488:A2CP1_RS03100
uniprot id: B8JC56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

455488:A2CP1 RS10150
gene id: 455488:A2CP1_RS10150
uniprot id: B8J863
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

455488:A2CP1 RS22540
gene id: 455488:A2CP1_RS22540
uniprot id: B8JCT2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

455488:A2CP1 RS07335
gene id: 455488:A2CP1_RS07335
uniprot id: B8JHA2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

455488:A2CP1 RS17605
gene id: 455488:A2CP1_RS17605
uniprot id: B8J5G5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

455488:A2CP1 RS09030
gene id: 455488:A2CP1_RS09030
uniprot id: B8J6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS01225
gene id: 455488:A2CP1_RS01225
uniprot id: B8J908
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

455488:A2CP1 RS10235
gene id: 455488:A2CP1_RS10235
uniprot id: B8J880
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

455488:A2CP1 RS14145
gene id: 455488:A2CP1_RS14145
uniprot id: B8JE78
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

455488:A2CP1 RS10170
gene id: 455488:A2CP1_RS10170
uniprot id: B8J867
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

455488:A2CP1 RS02935
gene id: 455488:A2CP1_RS02935
uniprot id: B8JC26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

455488:A2CP1 RS11645
gene id: 455488:A2CP1_RS11645
uniprot id: B8JAD6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

455488:A2CP1 RS21445
gene id: 455488:A2CP1_RS21445
uniprot id: B8JAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS11740
gene id: 455488:A2CP1_RS11740
uniprot id: B8JAF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

455488:A2CP1 RS16690
gene id: 455488:A2CP1_RS16690
uniprot id: B8JHD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

455488:A2CP1 RS10190
gene id: 455488:A2CP1_RS10190
uniprot id: B8J871
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

455488:A2CP1 RS01425
gene id: 455488:A2CP1_RS01425
uniprot id: B8J9U3
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

455488:A2CP1 RS12710
gene id: 455488:A2CP1_RS12710
uniprot id: B8JCC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

455488:A2CP1 RS01990
gene id: 455488:A2CP1_RS01990
uniprot id: B8JAU8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS03910
gene id: 455488:A2CP1_RS03910
uniprot id: B8JDP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

455488:A2CP1 RS06930
gene id: 455488:A2CP1_RS06930
uniprot id: B8JH21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

455488:A2CP1 RS03505
gene id: 455488:A2CP1_RS03505
uniprot id: B8JD31
names: Similarity
messages: Belongs to the peptidase S41A family.

455488:A2CP1 RS07885
gene id: 455488:A2CP1_RS07885
uniprot id: B8J559
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

455488:A2CP1 RS15200
gene id: 455488:A2CP1_RS15200
uniprot id: B8JFH3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS02110
gene id: 455488:A2CP1_RS02110
uniprot id: B8JAX2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

455488:A2CP1 RS02490
gene id: 455488:A2CP1_RS02490
uniprot id: B8JB46
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

455488:A2CP1 RS17405
gene id: 455488:A2CP1_RS17405
uniprot id: B8J5C5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

455488:A2CP1 RS07080
gene id: 455488:A2CP1_RS07080
uniprot id: B8JH51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

455488:A2CP1 RS08295
gene id: 455488:A2CP1_RS08295
uniprot id: B8J5P7
names: Subcellular Location Annotation
messages: Secreted

455488:A2CP1 RS06695
gene id: 455488:A2CP1_RS06695
uniprot id: B8JGL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

455488:A2CP1 RS03280
gene id: 455488:A2CP1_RS03280
uniprot id: B8JCY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS22440
gene id: 455488:A2CP1_RS22440
uniprot id: B8JCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

455488:A2CP1 RS21985
gene id: 455488:A2CP1_RS21985
uniprot id: B8JBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

455488:A2CP1 RS05035
gene id: 455488:A2CP1_RS05035
uniprot id: B8JF05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

455488:A2CP1 RS09530
gene id: 455488:A2CP1_RS09530
uniprot id: B8J750
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

455488:A2CP1 RS21850
gene id: 455488:A2CP1_RS21850
uniprot id: B8JBQ0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

455488:A2CP1 RS03425
gene id: 455488:A2CP1_RS03425
uniprot id: B8JD15
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS21855
gene id: 455488:A2CP1_RS21855
uniprot id: B8JBQ1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

455488:A2CP1 RS20640
gene id: 455488:A2CP1_RS20640
uniprot id: B8J9N0
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

455488:A2CP1 RS20645
gene id: 455488:A2CP1_RS20645
uniprot id: B8J9N1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

455488:A2CP1 RS20980
gene id: 455488:A2CP1_RS20980
uniprot id: B8JAI4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

455488:A2CP1 RS21780
gene id: 455488:A2CP1_RS21780
uniprot id: B8JBN6
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

455488:A2CP1 RS04360
gene id: 455488:A2CP1_RS04360
uniprot id: B8JDY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

455488:A2CP1 RS10285
gene id: 455488:A2CP1_RS10285
uniprot id: B8J890
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

455488:A2CP1 RS07970
gene id: 455488:A2CP1_RS07970
uniprot id: B8J576
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS01430
gene id: 455488:A2CP1_RS01430
uniprot id: B8J9U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

455488:A2CP1 RS09085
gene id: 455488:A2CP1_RS09085
uniprot id: B8J6H2
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS15000
gene id: 455488:A2CP1_RS15000
uniprot id: B8JFD2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

455488:A2CP1 RS10855
gene id: 455488:A2CP1_RS10855
uniprot id: B8J994
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

455488:A2CP1 RS06350
gene id: 455488:A2CP1_RS06350
uniprot id: B8JGE3
names: Similarity
messages: Belongs to the peptidase M13 family.

455488:A2CP1 RS19050
gene id: 455488:A2CP1_RS19050
uniprot id: B8J7C4
names: Similarity
messages: Belongs to the intimin/invasin family.

455488:A2CP1 RS11900
gene id: 455488:A2CP1_RS11900
uniprot id: B8J859
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

455488:A2CP1 RS05975
gene id: 455488:A2CP1_RS05975
uniprot id: B8JFV3
names: Similarity
messages: Belongs to the UPF0173 family.

455488:A2CP1 RS05700
gene id: 455488:A2CP1_RS05700
uniprot id: B8JFP9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS17375
gene id: 455488:A2CP1_RS17375
uniprot id: B8J5B9
names: Similarity
messages: Belongs to the MEMO1 family.

455488:A2CP1 RS00765
gene id: 455488:A2CP1_RS00765
uniprot id: B8J8R3
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

455488:A2CP1 RS04660
gene id: 455488:A2CP1_RS04660
uniprot id: B8JEG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

455488:A2CP1 RS11520
gene id: 455488:A2CP1_RS11520
uniprot id: B8JAB1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

455488:A2CP1 RS09435
gene id: 455488:A2CP1_RS09435
uniprot id: B8J731
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

455488:A2CP1 RS16145
gene id: 455488:A2CP1_RS16145
uniprot id: B8JGQ4
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

455488:A2CP1 RS19565
gene id: 455488:A2CP1_RS19565
uniprot id: B8J7M6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

455488:A2CP1 RS02410
gene id: 455488:A2CP1_RS02410
uniprot id: B8JB31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

455488:A2CP1 RS15035
gene id: 455488:A2CP1_RS15035
uniprot id: B8JFE0
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS13390
gene id: 455488:A2CP1_RS13390
uniprot id: B8JDE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS17820
gene id: 455488:A2CP1_RS17820
uniprot id: B8J5K2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

455488:A2CP1 RS12945
gene id: 455488:A2CP1_RS12945
uniprot id: B8JCG6
names: Similarity
messages: Belongs to the MotB family.

455488:A2CP1 RS11675
gene id: 455488:A2CP1_RS11675
uniprot id: B8JAE2
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

455488:A2CP1 RS19575
gene id: 455488:A2CP1_RS19575
uniprot id: B8J7M8
names: Similarity
messages: Belongs to the thioesterase PaaI family.

455488:A2CP1 RS12395
gene id: 455488:A2CP1_RS12395
uniprot id: B8JBH2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

455488:A2CP1 RS12495
gene id: 455488:A2CP1_RS12495
uniprot id: B8JC79
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

455488:A2CP1 RS21810
gene id: 455488:A2CP1_RS21810
uniprot id: B8JBP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS07910
gene id: 455488:A2CP1_RS07910
uniprot id: B8J564
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

455488:A2CP1 RS01820
gene id: 455488:A2CP1_RS01820
uniprot id: B8JA23
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS20425
gene id: 455488:A2CP1_RS20425
uniprot id: B8J9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS00895
gene id: 455488:A2CP1_RS00895
uniprot id: B8J8T9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

455488:A2CP1 RS12670
gene id: 455488:A2CP1_RS12670
uniprot id: B8JCB3
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

455488:A2CP1 RS19585
gene id: 455488:A2CP1_RS19585
uniprot id: B8J7N0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

455488:A2CP1 RS06090
gene id: 455488:A2CP1_RS06090
uniprot id: B8JFX5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS22190
gene id: 455488:A2CP1_RS22190
uniprot id: B8JCK7
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS12595
gene id: 455488:A2CP1_RS12595
uniprot id: B8JC98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

455488:A2CP1 RS19175
gene id: 455488:A2CP1_RS19175
uniprot id: B8J7E9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

455488:A2CP1 RS00860
gene id: 455488:A2CP1_RS00860
uniprot id: B8J8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

455488:A2CP1 RS10100
gene id: 455488:A2CP1_RS10100
uniprot id: B8J853
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

455488:A2CP1 RS10575
gene id: 455488:A2CP1_RS10575
uniprot id: B8J940
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

455488:A2CP1 RS12295
gene id: 455488:A2CP1_RS12295
uniprot id: B8JBF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

455488:A2CP1 RS21030
gene id: 455488:A2CP1_RS21030
uniprot id: B8JAJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

455488:A2CP1 RS22130
gene id: 455488:A2CP1_RS22130
uniprot id: B8JCJ5
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS11530
gene id: 455488:A2CP1_RS11530
uniprot id: B8JAB3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

455488:A2CP1 RS01050
gene id: 455488:A2CP1_RS01050
uniprot id: B8J8X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

455488:A2CP1 RS03060
gene id: 455488:A2CP1_RS03060
uniprot id: B8JC49
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

455488:A2CP1 RS11610
gene id: 455488:A2CP1_RS11610
uniprot id: B8JAC9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

455488:A2CP1 RS10275
gene id: 455488:A2CP1_RS10275
uniprot id: B8J888
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

455488:A2CP1 RS12385
gene id: 455488:A2CP1_RS12385
uniprot id: B8JBH0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

455488:A2CP1 RS01650
gene id: 455488:A2CP1_RS01650
uniprot id: B8J9Y8
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

455488:A2CP1 RS01670
gene id: 455488:A2CP1_RS01670
uniprot id: B8J9Z2
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

455488:A2CP1 RS03650
gene id: 455488:A2CP1_RS03650
uniprot id: B8JD60
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS12205
gene id: 455488:A2CP1_RS12205
uniprot id: B8JBD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

455488:A2CP1 RS13560
gene id: 455488:A2CP1_RS13560
uniprot id: B8JDI0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

455488:A2CP1 RS04095
gene id: 455488:A2CP1_RS04095
uniprot id: B8JDT2
names: Similarity
messages: Belongs to the Lgt family.

455488:A2CP1 RS19020
gene id: 455488:A2CP1_RS19020
uniprot id: B8J6X8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

455488:A2CP1 RS21700
gene id: 455488:A2CP1_RS21700
uniprot id: B8JBM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

455488:A2CP1 RS13605
gene id: 455488:A2CP1_RS13605
uniprot id: B8JDJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

455488:A2CP1 RS20060
gene id: 455488:A2CP1_RS20060
uniprot id: B8J8L7
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

455488:A2CP1 RS04745
gene id: 455488:A2CP1_RS04745
uniprot id: B8JEH9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

455488:A2CP1 RS05360
gene id: 455488:A2CP1_RS05360
uniprot id: B8JF69
names: Similarity
messages: Belongs to the TPP enzyme family.

455488:A2CP1 RS00290
gene id: 455488:A2CP1_RS00290
uniprot id: B8J7S4
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

455488:A2CP1 RS05150
gene id: 455488:A2CP1_RS05150
uniprot id: B8JF29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

455488:A2CP1 RS19110
gene id: 455488:A2CP1_RS19110
uniprot id: B8J7D6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS01945
gene id: 455488:A2CP1_RS01945
uniprot id: B8JAT9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

455488:A2CP1 RS03560
gene id: 455488:A2CP1_RS03560
uniprot id: B8JD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

455488:A2CP1 RS18755
gene id: 455488:A2CP1_RS18755
uniprot id: B8J6S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

455488:A2CP1 RS18310
gene id: 455488:A2CP1_RS18310
uniprot id: B8J670
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

455488:A2CP1 RS08205
gene id: 455488:A2CP1_RS08205
uniprot id: B8J5N0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

455488:A2CP1 RS14105
gene id: 455488:A2CP1_RS14105
uniprot id: B8JE70
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS22715
gene id: 455488:A2CP1_RS22715
uniprot id: B8J7S7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

455488:A2CP1 RS22585
gene id: 455488:A2CP1_RS22585
uniprot id: B8JCU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

455488:A2CP1 RS08325
gene id: 455488:A2CP1_RS08325
uniprot id: B8J5Q3
names: Similarity
messages: Belongs to the AHA1 family.

455488:A2CP1 RS01835
gene id: 455488:A2CP1_RS01835
uniprot id: B8JA26
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS05040
gene id: 455488:A2CP1_RS05040
uniprot id: B8JF06
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS10175
gene id: 455488:A2CP1_RS10175
uniprot id: B8J868
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

455488:A2CP1 RS21860
gene id: 455488:A2CP1_RS21860
uniprot id: B8JBQ2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

455488:A2CP1 RS14310
gene id: 455488:A2CP1_RS14310
uniprot id: B8JEN0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

455488:A2CP1 RS08010
gene id: 455488:A2CP1_RS08010
uniprot id: B8J584
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

455488:A2CP1 RS09305
gene id: 455488:A2CP1_RS09305
uniprot id: B8J6L4
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS02195
gene id: 455488:A2CP1_RS02195
uniprot id: B8JAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

455488:A2CP1 RS11175
gene id: 455488:A2CP1_RS11175
uniprot id: B8J9F5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

455488:A2CP1 RS22635
gene id: 455488:A2CP1_RS22635
uniprot id: B8JCV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

455488:A2CP1 RS12215
gene id: 455488:A2CP1_RS12215
uniprot id: B8JBD6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

455488:A2CP1 RS22650
gene id: 455488:A2CP1_RS22650
uniprot id: B8JCV4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

455488:A2CP1 RS16095
gene id: 455488:A2CP1_RS16095
uniprot id: B8JGP5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

455488:A2CP1 RS20245
gene id: 455488:A2CP1_RS20245
uniprot id: B8J8Q1
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

455488:A2CP1 RS22295
gene id: 455488:A2CP1_RS22295
uniprot id: B8JCM8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

455488:A2CP1 RS10215
gene id: 455488:A2CP1_RS10215
uniprot id: B8J876
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

455488:A2CP1 RS16040
gene id: 455488:A2CP1_RS16040
uniprot id: B8JGB8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

455488:A2CP1 RS02040
gene id: 455488:A2CP1_RS02040
uniprot id: B8JAV8
names: Similarity
messages: Belongs to the hemerythrin family.

455488:A2CP1 RS10140
gene id: 455488:A2CP1_RS10140
uniprot id: B8J861
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

455488:A2CP1 RS01125
gene id: 455488:A2CP1_RS01125
uniprot id: B8J8Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

455488:A2CP1 RS13005
gene id: 455488:A2CP1_RS13005
uniprot id: B8JCH8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

455488:A2CP1 RS20715
gene id: 455488:A2CP1_RS20715
uniprot id: B8J9P5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS14540
gene id: 455488:A2CP1_RS14540
uniprot id: B8JES4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

455488:A2CP1 RS02495
gene id: 455488:A2CP1_RS02495
uniprot id: B8JB47
names: Similarity
messages: Belongs to the HypE family.

455488:A2CP1 RS16120
gene id: 455488:A2CP1_RS16120
uniprot id: B8JGP9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

455488:A2CP1 RS04790
gene id: 455488:A2CP1_RS04790
uniprot id: B8JEI8
names: Similarity
messages: Belongs to the cytochrome c-552 family.

455488:A2CP1 RS07895
gene id: 455488:A2CP1_RS07895
uniprot id: B8J561
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS01440
gene id: 455488:A2CP1_RS01440
uniprot id: B8J9U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

455488:A2CP1 RS12320
gene id: 455488:A2CP1_RS12320
uniprot id: B8JBF7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

455488:A2CP1 RS01170
gene id: 455488:A2CP1_RS01170
uniprot id: B8J8Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

455488:A2CP1 RS21150
gene id: 455488:A2CP1_RS21150
uniprot id: B8JAL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

455488:A2CP1 RS00655
gene id: 455488:A2CP1_RS00655
uniprot id: B8J7Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

455488:A2CP1 RS07205
gene id: 455488:A2CP1_RS07205
uniprot id: B8JH77
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS07500
gene id: 455488:A2CP1_RS07500
uniprot id: B8J4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS00690
gene id: 455488:A2CP1_RS00690
uniprot id: B8J804
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

455488:A2CP1 RS11070
gene id: 455488:A2CP1_RS11070
uniprot id: B8J9D4
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

455488:A2CP1 RS20400
gene id: 455488:A2CP1_RS20400
uniprot id: B8J9I1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

455488:A2CP1 RS11460
gene id: 455488:A2CP1_RS11460
uniprot id: B8JA99
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

455488:A2CP1 RS18400
gene id: 455488:A2CP1_RS18400
uniprot id: B8J685
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

455488:A2CP1 RS10995
gene id: 455488:A2CP1_RS10995
uniprot id: B8J9C1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

455488:A2CP1 RS04920
gene id: 455488:A2CP1_RS04920
uniprot id: B8JEL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS04255
gene id: 455488:A2CP1_RS04255
uniprot id: B8JDW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS13640
gene id: 455488:A2CP1_RS13640
uniprot id: B8JDJ7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

455488:A2CP1 RS02515
gene id: 455488:A2CP1_RS02515
uniprot id: B8JB51
names: Similarity
messages: Belongs to the peptidase A31 family.

455488:A2CP1 RS08070
gene id: 455488:A2CP1_RS08070
uniprot id: B8J596
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

455488:A2CP1 RS01640
gene id: 455488:A2CP1_RS01640
uniprot id: B8J9Y6
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS10405
gene id: 455488:A2CP1_RS10405
uniprot id: B8J8B4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

455488:A2CP1 RS00235
gene id: 455488:A2CP1_RS00235
uniprot id: B8J7R3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS00030
gene id: 455488:A2CP1_RS00030
uniprot id: B8J6Y5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

455488:A2CP1 RS11470
gene id: 455488:A2CP1_RS11470
uniprot id: B8JAA1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

455488:A2CP1 RS08050
gene id: 455488:A2CP1_RS08050
uniprot id: B8J592
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Belongs to the TonB-dependent receptor family.
messages: Cell inner membrane
messages: Cell outer membrane
messages: Membrane

455488:A2CP1 RS03565
gene id: 455488:A2CP1_RS03565
uniprot id: B8JD43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Membrane

455488:A2CP1 RS15675
gene id: 455488:A2CP1_RS15675
uniprot id: B8JG43
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS04495
gene id: 455488:A2CP1_RS04495
uniprot id: B8JED0
names: Similarity
messages: Belongs to the peptidase S1C family.

455488:A2CP1 RS03690
gene id: 455488:A2CP1_RS03690
uniprot id: B8JD68
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

455488:A2CP1 RS11125
gene id: 455488:A2CP1_RS11125
uniprot id: B8J9E5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

455488:A2CP1 RS15240
gene id: 455488:A2CP1_RS15240
uniprot id: B8JFI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

455488:A2CP1 RS19025
gene id: 455488:A2CP1_RS19025
uniprot id: B8J6X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

455488:A2CP1 RS13820
gene id: 455488:A2CP1_RS13820
uniprot id: B8JE17
names: Similarity
messages: Belongs to the UPF0162 family.

455488:A2CP1 RS05020
gene id: 455488:A2CP1_RS05020
uniprot id: B8JF02
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS22090
gene id: 455488:A2CP1_RS22090
uniprot id: B8JCI7
names: Similarity
messages: Belongs to the pyruvate kinase family.

455488:A2CP1 RS06180
gene id: 455488:A2CP1_RS06180
uniprot id: B8JFZ3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

455488:A2CP1 RS02505
gene id: 455488:A2CP1_RS02505
uniprot id: B8JB49
names: Similarity
messages: Belongs to the HupF/HypC family.

455488:A2CP1 RS11395
gene id: 455488:A2CP1_RS11395
uniprot id: B8JA86
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

455488:A2CP1 RS14250
gene id: 455488:A2CP1_RS14250
uniprot id: B8JE99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

455488:A2CP1 RS05155
gene id: 455488:A2CP1_RS05155
uniprot id: B8JF30
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS00695
gene id: 455488:A2CP1_RS00695
uniprot id: B8J805
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

455488:A2CP1 RS20465
gene id: 455488:A2CP1_RS20465
uniprot id: B8J9J4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

455488:A2CP1 RS06175
gene id: 455488:A2CP1_RS06175
uniprot id: B8JFZ2
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

455488:A2CP1 RS17175
gene id: 455488:A2CP1_RS17175
uniprot id: B8JHN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

455488:A2CP1 RS06280
gene id: 455488:A2CP1_RS06280
uniprot id: B8JGC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

455488:A2CP1 RS19180
gene id: 455488:A2CP1_RS19180
uniprot id: B8J7F0
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

455488:A2CP1 RS07405
gene id: 455488:A2CP1_RS07405
uniprot id: B8JHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

455488:A2CP1 RS20430
gene id: 455488:A2CP1_RS20430
uniprot id: B8J9I7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

455488:A2CP1 RS20335
gene id: 455488:A2CP1_RS20335
uniprot id: B8J9G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

455488:A2CP1 RS09260
gene id: 455488:A2CP1_RS09260
uniprot id: B8J6K5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS09150
gene id: 455488:A2CP1_RS09150
uniprot id: B8J6I5
names: Subcellular Location Annotation
messages: Cytoplasm

455488:A2CP1 RS07125
gene id: 455488:A2CP1_RS07125
uniprot id: B8JH60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS09320
gene id: 455488:A2CP1_RS09320
uniprot id: B8J708
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

455488:A2CP1 RS06860
gene id: 455488:A2CP1_RS06860
uniprot id: B8JH07
names: Similarity
messages: Belongs to the arginase family.

455488:A2CP1 RS02835
gene id: 455488:A2CP1_RS02835
uniprot id: B8JC06
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS13690
gene id: 455488:A2CP1_RS13690
uniprot id: B8JDZ1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

455488:A2CP1 RS21805
gene id: 455488:A2CP1_RS21805
uniprot id: B8JBP1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS21350
gene id: 455488:A2CP1_RS21350
uniprot id: B8JAQ9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS11585
gene id: 455488:A2CP1_RS11585
uniprot id: B8JAC4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

455488:A2CP1 RS12725
gene id: 455488:A2CP1_RS12725
uniprot id: B8JCC4
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS21205
gene id: 455488:A2CP1_RS21205
uniprot id: B8JAM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

455488:A2CP1 RS08395
gene id: 455488:A2CP1_RS08395
uniprot id: B8J5R8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

455488:A2CP1 RS10565
gene id: 455488:A2CP1_RS10565
uniprot id: B8J938
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

455488:A2CP1 RS00675
gene id: 455488:A2CP1_RS00675
uniprot id: B8J801
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

455488:A2CP1 RS10135
gene id: 455488:A2CP1_RS10135
uniprot id: B8J860
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

455488:A2CP1 RS08855
gene id: 455488:A2CP1_RS08855
uniprot id: B8J6C5
names: Function
names: Similarity
messages: Belongs to the NifW family.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

455488:A2CP1 RS09570
gene id: 455488:A2CP1_RS09570
uniprot id: B8J758
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

455488:A2CP1 RS16070
gene id: 455488:A2CP1_RS16070
uniprot id: B8JGP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

455488:A2CP1 RS17750
gene id: 455488:A2CP1_RS17750
uniprot id: B8J5I8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

455488:A2CP1 RS01025
gene id: 455488:A2CP1_RS01025
uniprot id: B8J8W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

455488:A2CP1 RS20865
gene id: 455488:A2CP1_RS20865
uniprot id: B8J9S1
names: Similarity
messages: Belongs to the peptidase C40 family.

455488:A2CP1 RS02670
gene id: 455488:A2CP1_RS02670
uniprot id: B8JBX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

455488:A2CP1 RS00560
gene id: 455488:A2CP1_RS00560
uniprot id: B8J7X8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

455488:A2CP1 RS00225
gene id: 455488:A2CP1_RS00225
uniprot id: B8J7R1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS07350
gene id: 455488:A2CP1_RS07350
uniprot id: B8JHA5
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

455488:A2CP1 RS13205
gene id: 455488:A2CP1_RS13205
uniprot id: B8JDA9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

455488:A2CP1 RS08845
gene id: 455488:A2CP1_RS08845
uniprot id: B8J6C3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS03795
gene id: 455488:A2CP1_RS03795
uniprot id: B8JDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

455488:A2CP1 RS22060
gene id: 455488:A2CP1_RS22060
uniprot id: B8JBU3
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS02975
gene id: 455488:A2CP1_RS02975
uniprot id: B8JC32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

455488:A2CP1 RS18905
gene id: 455488:A2CP1_RS18905
uniprot id: B8J6V6
names: Similarity
messages: Belongs to the CinA family.

455488:A2CP1 RS06195
gene id: 455488:A2CP1_RS06195
uniprot id: B8JFZ6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

455488:A2CP1 RS15935
gene id: 455488:A2CP1_RS15935
uniprot id: B8JG97
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

455488:A2CP1 RS19355
gene id: 455488:A2CP1_RS19355
uniprot id: B8J7I5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

455488:A2CP1 RS11350
gene id: 455488:A2CP1_RS11350
uniprot id: B8JA77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

455488:A2CP1 RS16475
gene id: 455488:A2CP1_RS16475
uniprot id: B8JGW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

455488:A2CP1 RS09940
gene id: 455488:A2CP1_RS09940
uniprot id: B8J822
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

455488:A2CP1 RS07065
gene id: 455488:A2CP1_RS07065
uniprot id: B8JH48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

455488:A2CP1 RS09290
gene id: 455488:A2CP1_RS09290
uniprot id: B8J6L1
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS11325
gene id: 455488:A2CP1_RS11325
uniprot id: B8JA72
names: Activity Regulation
names: Caution
names: Domain
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

455488:A2CP1 RS00405
gene id: 455488:A2CP1_RS00405
uniprot id: B8J7U7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

455488:A2CP1 RS06025
gene id: 455488:A2CP1_RS06025
uniprot id: B8JFW2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

455488:A2CP1 RS20340
gene id: 455488:A2CP1_RS20340
uniprot id: B8J9G9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS02260
gene id: 455488:A2CP1_RS02260
uniprot id: B8JB02
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

455488:A2CP1 RS01925
gene id: 455488:A2CP1_RS01925
uniprot id: B8JAT5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

455488:A2CP1 RS02890
gene id: 455488:A2CP1_RS02890
uniprot id: B8JC17
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00415
gene id: 455488:A2CP1_RS00415
uniprot id: B8J7U9
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00250
gene id: 455488:A2CP1_RS00250
uniprot id: B8J7R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

455488:A2CP1 RS22515
gene id: 455488:A2CP1_RS22515
uniprot id: B8JCS7
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS00075
gene id: 455488:A2CP1_RS00075
uniprot id: B8J6Z3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

455488:A2CP1 RS09760
gene id: 455488:A2CP1_RS09760
uniprot id: B8J796
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

455488:A2CP1 RS04250
gene id: 455488:A2CP1_RS04250
uniprot id: B8JDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

455488:A2CP1 RS11420
gene id: 455488:A2CP1_RS11420
uniprot id: B8JA91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

455488:A2CP1 RS12540
gene id: 455488:A2CP1_RS12540
uniprot id: B8JC87
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS01270
gene id: 455488:A2CP1_RS01270
uniprot id: B8J917
names: Similarity
messages: Belongs to the peptidase S8 family.

455488:A2CP1 RS17620
gene id: 455488:A2CP1_RS17620
uniprot id: B8J5G8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

455488:A2CP1 RS20720
gene id: 455488:A2CP1_RS20720
uniprot id: B8J9P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

455488:A2CP1 RS08685
gene id: 455488:A2CP1_RS08685
uniprot id: B8J5X5
names: Similarity
messages: Belongs to the P(II) protein family.

455488:A2CP1 RS16575
gene id: 455488:A2CP1_RS16575
uniprot id: B8JGY9
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

455488:A2CP1 RS02345
gene id: 455488:A2CP1_RS02345
uniprot id: B8JB18
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS15090
gene id: 455488:A2CP1_RS15090
uniprot id: B8JFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

455488:A2CP1 RS08760
gene id: 455488:A2CP1_RS08760
uniprot id: B8J6A6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

455488:A2CP1 RS21740
gene id: 455488:A2CP1_RS21740
uniprot id: B8JBM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

455488:A2CP1 RS19140
gene id: 455488:A2CP1_RS19140
uniprot id: B8J7E2
names: Subcellular Location Annotation
messages: Membrane

455488:A2CP1 RS05890
gene id: 455488:A2CP1_RS05890
uniprot id: B8JFT6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

455488:A2CP1 RS14085
gene id: 455488:A2CP1_RS14085
uniprot id: B8JE66
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

455488:A2CP1 RS03535
gene id: 455488:A2CP1_RS03535
uniprot id: B8JD37
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

455488:A2CP1 RS04680
gene id: 455488:A2CP1_RS04680
uniprot id: B8JEG6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

455488:A2CP1 RS07315
gene id: 455488:A2CP1_RS07315
uniprot id: B8JH98
names: Similarity
messages: Belongs to the thioredoxin family.