453304:ATC03 RS03050
gene id: 453304:ATC03_RS03050
uniprot id: A0A191WCA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS15810
gene id: 453304:ATC03_RS15810
uniprot id: A0A191WIF5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS15225
gene id: 453304:ATC03_RS15225
uniprot id: A0A191WHT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

453304:ATC03 RS07280
gene id: 453304:ATC03_RS07280
uniprot id: A0A191WEF3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

453304:ATC03 RS02610
gene id: 453304:ATC03_RS02610
uniprot id: A0A191WCA1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

453304:ATC03 RS14455
gene id: 453304:ATC03_RS14455
uniprot id: A0A191WHN4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

453304:ATC03 RS15065
gene id: 453304:ATC03_RS15065
uniprot id: A0A191WHY5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS19305
gene id: 453304:ATC03_RS19305
uniprot id: A0A191WJX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS11520
gene id: 453304:ATC03_RS11520
uniprot id: A0A191WG77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

453304:ATC03 RS17810
gene id: 453304:ATC03_RS17810
uniprot id: A0A191WJ50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

453304:ATC03 RS03005
gene id: 453304:ATC03_RS03005
uniprot id: A0A191WC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

453304:ATC03 RS12060
gene id: 453304:ATC03_RS12060
uniprot id: A0A191WGF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

453304:ATC03 RS12725
gene id: 453304:ATC03_RS12725
uniprot id: A0A191WGQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

453304:ATC03 RS01670
gene id: 453304:ATC03_RS01670
uniprot id: A0A191WBP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS12585
gene id: 453304:ATC03_RS12585
uniprot id: A0A191WGW9
names: Similarity
messages: Belongs to the group II decarboxylase family.

453304:ATC03 RS00620
gene id: 453304:ATC03_RS00620
uniprot id: A0A191WB52
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

453304:ATC03 RS00935
gene id: 453304:ATC03_RS00935
uniprot id: A0A191WBH4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

453304:ATC03 RS16645
gene id: 453304:ATC03_RS16645
uniprot id: A0A191WIF6
names: Similarity
messages: Belongs to the HsdR family.

453304:ATC03 RS02705
gene id: 453304:ATC03_RS02705
uniprot id: A0A191WKF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

453304:ATC03 RS12640
gene id: 453304:ATC03_RS12640
uniprot id: A0A191WGX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

453304:ATC03 RS19425
gene id: 453304:ATC03_RS19425
uniprot id: A0A191WK38
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

453304:ATC03 RS08395
gene id: 453304:ATC03_RS08395
uniprot id: A0A191WEV6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

453304:ATC03 RS15990
gene id: 453304:ATC03_RS15990
uniprot id: A0A191WII2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

453304:ATC03 RS08465
gene id: 453304:ATC03_RS08465
uniprot id: A0A191WEN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

453304:ATC03 RS11325
gene id: 453304:ATC03_RS11325
uniprot id: A0A191WGC3
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS12595
gene id: 453304:ATC03_RS12595
uniprot id: A0A191WGJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

453304:ATC03 RS08350
gene id: 453304:ATC03_RS08350
uniprot id: A0A191WEW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

453304:ATC03 RS11295
gene id: 453304:ATC03_RS11295
uniprot id: A0A191WGB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS18290
gene id: 453304:ATC03_RS18290
uniprot id: A0A191WJ58
names: Similarity
messages: Belongs to the sulfatase family.

453304:ATC03 RS14145
gene id: 453304:ATC03_RS14145
uniprot id: A0A191WHM3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

453304:ATC03 RS05065
gene id: 453304:ATC03_RS05065
uniprot id: A0A191WD42
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

453304:ATC03 RS07100
gene id: 453304:ATC03_RS07100
uniprot id: A0A191WE24
names: Similarity
messages: Belongs to the FBPase class 2 family.

453304:ATC03 RS09575
gene id: 453304:ATC03_RS09575
uniprot id: A0A191WF71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

453304:ATC03 RS06280
gene id: 453304:ATC03_RS06280
uniprot id: A0A191WDV5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

453304:ATC03 RS02140
gene id: 453304:ATC03_RS02140
uniprot id: A0A191WBV6
names: Similarity
messages: Belongs to the CsoR family.

453304:ATC03 RS01580
gene id: 453304:ATC03_RS01580
uniprot id: A0A191WBL3
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS04170
gene id: 453304:ATC03_RS04170
uniprot id: A0A191WCQ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

453304:ATC03 RS16090
gene id: 453304:ATC03_RS16090
uniprot id: A0A191WI63
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

453304:ATC03 RS08045
gene id: 453304:ATC03_RS08045
uniprot id: A0A191WEL5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

453304:ATC03 RS03870
gene id: 453304:ATC03_RS03870
uniprot id: A0A191WCT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

453304:ATC03 RS15145
gene id: 453304:ATC03_RS15145
uniprot id: A0A191WHV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

453304:ATC03 RS16565
gene id: 453304:ATC03_RS16565
uniprot id: A0A191WIJ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

453304:ATC03 RS15160
gene id: 453304:ATC03_RS15160
uniprot id: A0A191WI50
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

453304:ATC03 RS18645
gene id: 453304:ATC03_RS18645
uniprot id: A0A191WJM0
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS19060
gene id: 453304:ATC03_RS19060
uniprot id: A0A191WJT3
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS14510
gene id: 453304:ATC03_RS14510
uniprot id: A0A191WHT4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

453304:ATC03 RS04130
gene id: 453304:ATC03_RS04130
uniprot id: A0A191WCV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

453304:ATC03 RS17760
gene id: 453304:ATC03_RS17760
uniprot id: A0A191WJ40
names: Similarity
messages: Belongs to the SAICAR synthetase family.

453304:ATC03 RS13275
gene id: 453304:ATC03_RS13275
uniprot id: A0A191WGZ9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

453304:ATC03 RS14180
gene id: 453304:ATC03_RS14180
uniprot id: A0A191WHM7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

453304:ATC03 RS07845
gene id: 453304:ATC03_RS07845
uniprot id: A0A191WED9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

453304:ATC03 RS19285
gene id: 453304:ATC03_RS19285
uniprot id: A0A191WK14
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

453304:ATC03 RS14675
gene id: 453304:ATC03_RS14675
uniprot id: A0A191WHS2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

453304:ATC03 RS00600
gene id: 453304:ATC03_RS00600
uniprot id: A0A191WBB4
names: Similarity
messages: Belongs to the peptidase M13 family.

453304:ATC03 RS00360
gene id: 453304:ATC03_RS00360
uniprot id: A0A191WB18
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

453304:ATC03 RS10105
gene id: 453304:ATC03_RS10105
uniprot id: A0A191WFJ3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

453304:ATC03 RS09395
gene id: 453304:ATC03_RS09395
uniprot id: A0A191WF94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

453304:ATC03 RS10780
gene id: 453304:ATC03_RS10780
uniprot id: A0A191WKV1
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

453304:ATC03 RS09735
gene id: 453304:ATC03_RS09735
uniprot id: A0A191WF99
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

453304:ATC03 RS07390
gene id: 453304:ATC03_RS07390
uniprot id: A0A191WE69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS07655
gene id: 453304:ATC03_RS07655
uniprot id: A0A191WEJ7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

453304:ATC03 RS13295
gene id: 453304:ATC03_RS13295
uniprot id: A0A191WGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

453304:ATC03 RS11495
gene id: 453304:ATC03_RS11495
uniprot id: A0A191WGG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

453304:ATC03 RS19020
gene id: 453304:ATC03_RS19020
uniprot id: A0A191WJG6
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

453304:ATC03 RS00560
gene id: 453304:ATC03_RS00560
uniprot id: A0A191WB68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

453304:ATC03 RS11285
gene id: 453304:ATC03_RS11285
uniprot id: A0A191WG30
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

453304:ATC03 RS09385
gene id: 453304:ATC03_RS09385
uniprot id: A0A191WF37
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

453304:ATC03 RS14350
gene id: 453304:ATC03_RS14350
uniprot id: A0A191WL72
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

453304:ATC03 RS00075
gene id: 453304:ATC03_RS00075
uniprot id: A0A191WAX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

453304:ATC03 RS16875
gene id: 453304:ATC03_RS16875
uniprot id: A0A191WIY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS17130
gene id: 453304:ATC03_RS17130
uniprot id: A0A191WJ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS13595
gene id: 453304:ATC03_RS13595
uniprot id: A0A191WH50
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

453304:ATC03 RS02155
gene id: 453304:ATC03_RS02155
uniprot id: A0A191WC31
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS11300
gene id: 453304:ATC03_RS11300
uniprot id: A0A191WGA5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS13405
gene id: 453304:ATC03_RS13405
uniprot id: A0A191WH58
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

453304:ATC03 RS18730
gene id: 453304:ATC03_RS18730
uniprot id: A0A191WJJ3
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS03980
gene id: 453304:ATC03_RS03980
uniprot id: A0A191WCM7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

453304:ATC03 RS10290
gene id: 453304:ATC03_RS10290
uniprot id: A0A191WFU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

453304:ATC03 RS10895
gene id: 453304:ATC03_RS10895
uniprot id: A0A191WFT9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

453304:ATC03 RS04115
gene id: 453304:ATC03_RS04115
uniprot id: A0A191WCP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS02915
gene id: 453304:ATC03_RS02915
uniprot id: A0A191WCE6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

453304:ATC03 RS16950
gene id: 453304:ATC03_RS16950
uniprot id: A0A191WIZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

453304:ATC03 RS09470
gene id: 453304:ATC03_RS09470
uniprot id: A0A191WFB0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS09130
gene id: 453304:ATC03_RS09130
uniprot id: A0A191WF92
names: Similarity
messages: Belongs to the LacAB/RpiB family.

453304:ATC03 RS14505
gene id: 453304:ATC03_RS14505
uniprot id: A0A191WHT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

453304:ATC03 RS02760
gene id: 453304:ATC03_RS02760
uniprot id: A0A191WC42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

453304:ATC03 RS01815
gene id: 453304:ATC03_RS01815
uniprot id: A0A191WBX1
names: Similarity
messages: Belongs to the UPF0234 family.

453304:ATC03 RS06330
gene id: 453304:ATC03_RS06330
uniprot id: A0A191WDU2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

453304:ATC03 RS08150
gene id: 453304:ATC03_RS08150
uniprot id: A0A191WEN5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

453304:ATC03 RS00850
gene id: 453304:ATC03_RS00850
uniprot id: A0A191WBH1
names: Similarity
messages: Belongs to the PrpD family.

453304:ATC03 RS16925
gene id: 453304:ATC03_RS16925
uniprot id: A0A191WIJ9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

453304:ATC03 RS14590
gene id: 453304:ATC03_RS14590
uniprot id: A0A191WHL8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

453304:ATC03 RS09720
gene id: 453304:ATC03_RS09720
uniprot id: A0A191WFF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

453304:ATC03 RS06295
gene id: 453304:ATC03_RS06295
uniprot id: A0A191WDP2
names: Subcellular Location Annotation
messages: Cytoplasm

453304:ATC03 RS03720
gene id: 453304:ATC03_RS03720
uniprot id: A0A191WCQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

453304:ATC03 RS05505
gene id: 453304:ATC03_RS05505
uniprot id: A0A191WDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS17515
gene id: 453304:ATC03_RS17515
uniprot id: A0A191WJ41
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS14910
gene id: 453304:ATC03_RS14910
uniprot id: A0A191WHV9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

453304:ATC03 RS12540
gene id: 453304:ATC03_RS12540
uniprot id: A0A191WL12
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

453304:ATC03 RS03940
gene id: 453304:ATC03_RS03940
uniprot id: A0A191WCM2
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

453304:ATC03 RS15350
gene id: 453304:ATC03_RS15350
uniprot id: A0A191WI80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

453304:ATC03 RS19260
gene id: 453304:ATC03_RS19260
uniprot id: A0A191WJK9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

453304:ATC03 RS12965
gene id: 453304:ATC03_RS12965
uniprot id: A0A191WGR2
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

453304:ATC03 RS18935
gene id: 453304:ATC03_RS18935
uniprot id: A0A191WJM2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

453304:ATC03 RS16060
gene id: 453304:ATC03_RS16060
uniprot id: A0A191WI58
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

453304:ATC03 RS19275
gene id: 453304:ATC03_RS19275
uniprot id: A0A191WJX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS06665
gene id: 453304:ATC03_RS06665
uniprot id: A0A191WDV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

453304:ATC03 RS11575
gene id: 453304:ATC03_RS11575
uniprot id: A0A191WKN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

453304:ATC03 RS03305
gene id: 453304:ATC03_RS03305
uniprot id: A0A191WCC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

453304:ATC03 RS15855
gene id: 453304:ATC03_RS15855
uniprot id: A0A191WIG1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

453304:ATC03 RS09870
gene id: 453304:ATC03_RS09870
uniprot id: A0A191WFC4
names: Similarity
messages: Belongs to the NDK family.

453304:ATC03 RS15535
gene id: 453304:ATC03_RS15535
uniprot id: A0A191WL86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

453304:ATC03 RS14475
gene id: 453304:ATC03_RS14475
uniprot id: A0A191WHG0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS08600
gene id: 453304:ATC03_RS08600
uniprot id: A0A191WEW3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

453304:ATC03 RS06030
gene id: 453304:ATC03_RS06030
uniprot id: A0A191WDJ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

453304:ATC03 RS05470
gene id: 453304:ATC03_RS05470
uniprot id: A0A191WDB9
names: Similarity
messages: Belongs to the RutC family.

453304:ATC03 RS19350
gene id: 453304:ATC03_RS19350
uniprot id: A0A191WJU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

453304:ATC03 RS12010
gene id: 453304:ATC03_RS12010
uniprot id: A0A191WGI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS08130
gene id: 453304:ATC03_RS08130
uniprot id: A0A191WES5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

453304:ATC03 RS13820
gene id: 453304:ATC03_RS13820
uniprot id: A0A191WHH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS02975
gene id: 453304:ATC03_RS02975
uniprot id: A0A191WC95
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

453304:ATC03 RS18975
gene id: 453304:ATC03_RS18975
uniprot id: A0A191WJX2
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS11470
gene id: 453304:ATC03_RS11470
uniprot id: A0A191WGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS02310
gene id: 453304:ATC03_RS02310
uniprot id: A0A191WKA0
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

453304:ATC03 RS14630
gene id: 453304:ATC03_RS14630
uniprot id: A0A191WHV8
names: Similarity
messages: Belongs to the TPP enzyme family.

453304:ATC03 RS11445
gene id: 453304:ATC03_RS11445
uniprot id: A0A191WGE3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

453304:ATC03 RS03480
gene id: 453304:ATC03_RS03480
uniprot id: A0A191WK43
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

453304:ATC03 RS13590
gene id: 453304:ATC03_RS13590
uniprot id: A0A191WH11
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

453304:ATC03 RS06475
gene id: 453304:ATC03_RS06475
uniprot id: A0A191WDW8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS04195
gene id: 453304:ATC03_RS04195
uniprot id: A0A191WCQ7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

453304:ATC03 RS08485
gene id: 453304:ATC03_RS08485
uniprot id: A0A191WEY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

453304:ATC03 RS09060
gene id: 453304:ATC03_RS09060
uniprot id: A0A191WF08
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

453304:ATC03 RS02560
gene id: 453304:ATC03_RS02560
uniprot id: A0A191WC36
names: Similarity
messages: Belongs to the CdaR family.

453304:ATC03 RS16525
gene id: 453304:ATC03_RS16525
uniprot id: A0A191WID6
names: Similarity
messages: Belongs to the peptidase S33 family.

453304:ATC03 RS01870
gene id: 453304:ATC03_RS01870
uniprot id: A0A191WK46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS15920
gene id: 453304:ATC03_RS15920
uniprot id: A0A191WIC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

453304:ATC03 RS06015
gene id: 453304:ATC03_RS06015
uniprot id: A0A191WDR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS05850
gene id: 453304:ATC03_RS05850
uniprot id: A0A191WDH0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

453304:ATC03 RS06155
gene id: 453304:ATC03_RS06155
uniprot id: A0A191WDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

453304:ATC03 RS19390
gene id: 453304:ATC03_RS19390
uniprot id: A0A191WK50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS03390
gene id: 453304:ATC03_RS03390
uniprot id: A0A191WCL5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

453304:ATC03 RS03485
gene id: 453304:ATC03_RS03485
uniprot id: A0A191WCN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

453304:ATC03 RS14345
gene id: 453304:ATC03_RS14345
uniprot id: A0A191WHQ8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS00925
gene id: 453304:ATC03_RS00925
uniprot id: A0A191WBB3
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS02880
gene id: 453304:ATC03_RS02880
uniprot id: A0A191WCC7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

453304:ATC03 RS00990
gene id: 453304:ATC03_RS00990
uniprot id: A0A191WBJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

453304:ATC03 RS17125
gene id: 453304:ATC03_RS17125
uniprot id: A0A191WJ14
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09570
gene id: 453304:ATC03_RS09570
uniprot id: A0A191WFH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

453304:ATC03 RS16540
gene id: 453304:ATC03_RS16540
uniprot id: A0A191WIN4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

453304:ATC03 RS14950
gene id: 453304:ATC03_RS14950
uniprot id: A0A191WI13
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

453304:ATC03 RS15745
gene id: 453304:ATC03_RS15745
uniprot id: A0A191WLE6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

453304:ATC03 RS04635
gene id: 453304:ATC03_RS04635
uniprot id: A0A191WD43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

453304:ATC03 RS09805
gene id: 453304:ATC03_RS09805
uniprot id: A0A191WFL1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

453304:ATC03 RS08265
gene id: 453304:ATC03_RS08265
uniprot id: A0A191WEK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS02520
gene id: 453304:ATC03_RS02520
uniprot id: A0A191WC12
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

453304:ATC03 RS07040
gene id: 453304:ATC03_RS07040
uniprot id: A0A191WE61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS11330
gene id: 453304:ATC03_RS11330
uniprot id: A0A191WGB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

453304:ATC03 RS01200
gene id: 453304:ATC03_RS01200
uniprot id: A0A191WBL9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS17355
gene id: 453304:ATC03_RS17355
uniprot id: A0A191WJ52
names: Similarity
messages: Belongs to the XFP family.

453304:ATC03 RS01000
gene id: 453304:ATC03_RS01000
uniprot id: A0A191WBC8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09405
gene id: 453304:ATC03_RS09405
uniprot id: A0A191WFE2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

453304:ATC03 RS18035
gene id: 453304:ATC03_RS18035
uniprot id: A0A191WJ24
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS15295
gene id: 453304:ATC03_RS15295
uniprot id: A0A191WI74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

453304:ATC03 RS12535
gene id: 453304:ATC03_RS12535
uniprot id: A0A191WGI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS15315
gene id: 453304:ATC03_RS15315
uniprot id: A0A191WI32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

453304:ATC03 RS08655
gene id: 453304:ATC03_RS08655
uniprot id: A0A191WER9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

453304:ATC03 RS10525
gene id: 453304:ATC03_RS10525
uniprot id: A0A191WFR2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

453304:ATC03 RS18950
gene id: 453304:ATC03_RS18950
uniprot id: A0A191WJX0
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS19580
gene id: 453304:ATC03_RS19580
uniprot id: A0A191WJZ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

453304:ATC03 RS14760
gene id: 453304:ATC03_RS14760
uniprot id: A0A191WHP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

453304:ATC03 RS10400
gene id: 453304:ATC03_RS10400
uniprot id: A0A191WFL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

453304:ATC03 RS00345
gene id: 453304:ATC03_RS00345
uniprot id: A0A191WB34
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS15010
gene id: 453304:ATC03_RS15010
uniprot id: A0A191WHX5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS14865
gene id: 453304:ATC03_RS14865
uniprot id: A0A191WHZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

453304:ATC03 RS17100
gene id: 453304:ATC03_RS17100
uniprot id: A0A191WJ13
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

453304:ATC03 RS10380
gene id: 453304:ATC03_RS10380
uniprot id: A0A191WFN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

453304:ATC03 RS09030
gene id: 453304:ATC03_RS09030
uniprot id: A0A191WEY2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

453304:ATC03 RS05980
gene id: 453304:ATC03_RS05980
uniprot id: A0A191WDI9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

453304:ATC03 RS12405
gene id: 453304:ATC03_RS12405
uniprot id: A0A191WGT3
names: Similarity
messages: Belongs to the TlyA family.

453304:ATC03 RS03860
gene id: 453304:ATC03_RS03860
uniprot id: A0A191WCK7
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

453304:ATC03 RS17835
gene id: 453304:ATC03_RS17835
uniprot id: A0A191WIZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS09360
gene id: 453304:ATC03_RS09360
uniprot id: A0A191WKI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

453304:ATC03 RS18295
gene id: 453304:ATC03_RS18295
uniprot id: A0A191WJC2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

453304:ATC03 RS04580
gene id: 453304:ATC03_RS04580
uniprot id: A0A191WKL6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS07110
gene id: 453304:ATC03_RS07110
uniprot id: A0A191WE71
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS06305
gene id: 453304:ATC03_RS06305
uniprot id: A0A191WDW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

453304:ATC03 RS01405
gene id: 453304:ATC03_RS01405
uniprot id: A0A191WBQ8
names: Similarity
messages: Belongs to the type IB topoisomerase family.

453304:ATC03 RS19415
gene id: 453304:ATC03_RS19415
uniprot id: A0A191WK53
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

453304:ATC03 RS06750
gene id: 453304:ATC03_RS06750
uniprot id: A0A191WDW3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

453304:ATC03 RS17780
gene id: 453304:ATC03_RS17780
uniprot id: A0A191WIY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

453304:ATC03 RS06725
gene id: 453304:ATC03_RS06725
uniprot id: A0A191WDW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

453304:ATC03 RS11235
gene id: 453304:ATC03_RS11235
uniprot id: A0A191WG55
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

453304:ATC03 RS01605
gene id: 453304:ATC03_RS01605
uniprot id: A0A191WKB7
names: Similarity
messages: Belongs to the YciI family.

453304:ATC03 RS15280
gene id: 453304:ATC03_RS15280
uniprot id: A0A191WHU2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

453304:ATC03 RS17380
gene id: 453304:ATC03_RS17380
uniprot id: A0A191WJ56
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

453304:ATC03 RS01515
gene id: 453304:ATC03_RS01515
uniprot id: A0A191WBS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS06660
gene id: 453304:ATC03_RS06660
uniprot id: A0A191WDU9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS13765
gene id: 453304:ATC03_RS13765
uniprot id: A0A191WHG3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

453304:ATC03 RS03475
gene id: 453304:ATC03_RS03475
uniprot id: A0A191WCL9
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

453304:ATC03 RS11580
gene id: 453304:ATC03_RS11580
uniprot id: A0A191WG48
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS17535
gene id: 453304:ATC03_RS17535
uniprot id: A0A191WJ05
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

453304:ATC03 RS15265
gene id: 453304:ATC03_RS15265
uniprot id: A0A191WI22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

453304:ATC03 RS13160
gene id: 453304:ATC03_RS13160
uniprot id: A0A191WGY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

453304:ATC03 RS17285
gene id: 453304:ATC03_RS17285
uniprot id: A0A191WJ42
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS11610
gene id: 453304:ATC03_RS11610
uniprot id: A0A191WG51
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

453304:ATC03 RS01395
gene id: 453304:ATC03_RS01395
uniprot id: A0A191WBK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

453304:ATC03 RS17965
gene id: 453304:ATC03_RS17965
uniprot id: A0A191WJB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

453304:ATC03 RS09370
gene id: 453304:ATC03_RS09370
uniprot id: A0A191WF90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

453304:ATC03 RS02860
gene id: 453304:ATC03_RS02860
uniprot id: A0A191WCD6
names: Similarity
messages: Belongs to the acylphosphatase family.

453304:ATC03 RS03340
gene id: 453304:ATC03_RS03340
uniprot id: A0A191WCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS06950
gene id: 453304:ATC03_RS06950
uniprot id: A0A191WE47
names: Similarity
messages: Belongs to the SsuE family.

453304:ATC03 RS14175
gene id: 453304:ATC03_RS14175
uniprot id: A0A191WL67
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

453304:ATC03 RS09440
gene id: 453304:ATC03_RS09440
uniprot id: A0A191WF68
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

453304:ATC03 RS15180
gene id: 453304:ATC03_RS15180
uniprot id: A0A191WHW0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

453304:ATC03 RS03080
gene id: 453304:ATC03_RS03080
uniprot id: A0A191WCA9
names: Cofactor
messages: Can also use Mn(2+) ion.

453304:ATC03 RS17875
gene id: 453304:ATC03_RS17875
uniprot id: A0A191WIZ8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

453304:ATC03 RS14080
gene id: 453304:ATC03_RS14080
uniprot id: A0A191WHG6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS00005
gene id: 453304:ATC03_RS00005
uniprot id: A0A191WLL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

453304:ATC03 RS07480
gene id: 453304:ATC03_RS07480
uniprot id: A0A191WE76
names: Similarity
messages: Belongs to the DEAD box helicase family.

453304:ATC03 RS08040
gene id: 453304:ATC03_RS08040
uniprot id: A0A191WEG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS10340
gene id: 453304:ATC03_RS10340
uniprot id: A0A191WFV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

453304:ATC03 RS10585
gene id: 453304:ATC03_RS10585
uniprot id: A0A191WFS2
names: Similarity
messages: Belongs to the Dps family.

453304:ATC03 RS06375
gene id: 453304:ATC03_RS06375
uniprot id: A0A191WDQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS03225
gene id: 453304:ATC03_RS03225
uniprot id: A0A191WCH9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS19065
gene id: 453304:ATC03_RS19065
uniprot id: A0A191WJY7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

453304:ATC03 RS13850
gene id: 453304:ATC03_RS13850
uniprot id: A0A191WHH6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS05400
gene id: 453304:ATC03_RS05400
uniprot id: A0A191WDI5
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

453304:ATC03 RS14170
gene id: 453304:ATC03_RS14170
uniprot id: A0A191WHN0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

453304:ATC03 RS14240
gene id: 453304:ATC03_RS14240
uniprot id: A0A191WHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS15165
gene id: 453304:ATC03_RS15165
uniprot id: A0A191WI45
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

453304:ATC03 RS00010
gene id: 453304:ATC03_RS00010
uniprot id: A0A191WK70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

453304:ATC03 RS10195
gene id: 453304:ATC03_RS10195
uniprot id: A0A191WFT1
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS19555
gene id: 453304:ATC03_RS19555
uniprot id: A0A191WK12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS04365
gene id: 453304:ATC03_RS04365
uniprot id: A0A191WD26
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

453304:ATC03 RS06190
gene id: 453304:ATC03_RS06190
uniprot id: A0A191WDU0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS05940
gene id: 453304:ATC03_RS05940
uniprot id: A0A191WDP6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

453304:ATC03 RS06970
gene id: 453304:ATC03_RS06970
uniprot id: A0A191WE05
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS19240
gene id: 453304:ATC03_RS19240
uniprot id: A0A191WJS4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

453304:ATC03 RS00725
gene id: 453304:ATC03_RS00725
uniprot id: A0A191WB79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS05815
gene id: 453304:ATC03_RS05815
uniprot id: A0A191WDK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

453304:ATC03 RS09485
gene id: 453304:ATC03_RS09485
uniprot id: A0A191WF56
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

453304:ATC03 RS00405
gene id: 453304:ATC03_RS00405
uniprot id: A0A191WB15
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS14060
gene id: 453304:ATC03_RS14060
uniprot id: A0A191WH91
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

453304:ATC03 RS04805
gene id: 453304:ATC03_RS04805
uniprot id: A0A191WD05
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

453304:ATC03 RS08205
gene id: 453304:ATC03_RS08205
uniprot id: A0A191WKS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

453304:ATC03 RS08475
gene id: 453304:ATC03_RS08475
uniprot id: A0A191WET7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

453304:ATC03 RS03950
gene id: 453304:ATC03_RS03950
uniprot id: A0A191WCU1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

453304:ATC03 RS17210
gene id: 453304:ATC03_RS17210
uniprot id: A0A191WJ31
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

453304:ATC03 RS08515
gene id: 453304:ATC03_RS08515
uniprot id: A0A191WEZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

453304:ATC03 RS09765
gene id: 453304:ATC03_RS09765
uniprot id: A0A191WFD1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

453304:ATC03 RS03825
gene id: 453304:ATC03_RS03825
uniprot id: A0A191WKE9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

453304:ATC03 RS05275
gene id: 453304:ATC03_RS05275
uniprot id: A0A191WDB8
names: Similarity
messages: Belongs to the hyi family.

453304:ATC03 RS05990
gene id: 453304:ATC03_RS05990
uniprot id: A0A191WDQ5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

453304:ATC03 RS10500
gene id: 453304:ATC03_RS10500
uniprot id: A0A191WFU2
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

453304:ATC03 RS13170
gene id: 453304:ATC03_RS13170
uniprot id: A0A191WH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

453304:ATC03 RS15170
gene id: 453304:ATC03_RS15170
uniprot id: A0A191WHR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

453304:ATC03 RS00635
gene id: 453304:ATC03_RS00635
uniprot id: A0A191WBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS02840
gene id: 453304:ATC03_RS02840
uniprot id: A0A191WKF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

453304:ATC03 RS08360
gene id: 453304:ATC03_RS08360
uniprot id: A0A191WEN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

453304:ATC03 RS08605
gene id: 453304:ATC03_RS08605
uniprot id: A0A191WEZ7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

453304:ATC03 RS06625
gene id: 453304:ATC03_RS06625
uniprot id: A0A191WE48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS11975
gene id: 453304:ATC03_RS11975
uniprot id: A0A191WGE1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

453304:ATC03 RS00450
gene id: 453304:ATC03_RS00450
uniprot id: A0A191WK42
names: Similarity
messages: Belongs to the peptidase S9A family.

453304:ATC03 RS07330
gene id: 453304:ATC03_RS07330
uniprot id: A0A191WEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS09490
gene id: 453304:ATC03_RS09490
uniprot id: A0A191WF81
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS00505
gene id: 453304:ATC03_RS00505
uniprot id: A0A191WB98
names: Similarity
messages: Belongs to the glutathione peroxidase family.

453304:ATC03 RS12870
gene id: 453304:ATC03_RS12870
uniprot id: A0A191WGT1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

453304:ATC03 RS06795
gene id: 453304:ATC03_RS06795
uniprot id: A0A191WE50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

453304:ATC03 RS13620
gene id: 453304:ATC03_RS13620
uniprot id: A0A191WH16
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

453304:ATC03 RS12530
gene id: 453304:ATC03_RS12530
uniprot id: A0A191WGU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS00510
gene id: 453304:ATC03_RS00510
uniprot id: A0A191WBB1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

453304:ATC03 RS17705
gene id: 453304:ATC03_RS17705
uniprot id: A0A191WJ73
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS04005
gene id: 453304:ATC03_RS04005
uniprot id: A0A191WCW5
names: Similarity
messages: Belongs to the AHA1 family.

453304:ATC03 RS10160
gene id: 453304:ATC03_RS10160
uniprot id: A0A191WFS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

453304:ATC03 RS09380
gene id: 453304:ATC03_RS09380
uniprot id: A0A191WFD7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

453304:ATC03 RS05530
gene id: 453304:ATC03_RS05530
uniprot id: A0A191WDB6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

453304:ATC03 RS12555
gene id: 453304:ATC03_RS12555
uniprot id: A0A191WGW4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

453304:ATC03 RS19100
gene id: 453304:ATC03_RS19100
uniprot id: A0A191WJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS11435
gene id: 453304:ATC03_RS11435
uniprot id: A0A191WG60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

453304:ATC03 RS19505
gene id: 453304:ATC03_RS19505
uniprot id: A0A191WK64
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

453304:ATC03 RS01330
gene id: 453304:ATC03_RS01330
uniprot id: A0A191WBN4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

453304:ATC03 RS03350
gene id: 453304:ATC03_RS03350
uniprot id: A0A191WK39
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS19340
gene id: 453304:ATC03_RS19340
uniprot id: A0A191WK25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

453304:ATC03 RS00125
gene id: 453304:ATC03_RS00125
uniprot id: A0A191WB35
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

453304:ATC03 RS18075
gene id: 453304:ATC03_RS18075
uniprot id: A0A191WJ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

453304:ATC03 RS19650
gene id: 453304:ATC03_RS19650
uniprot id: A0A191WJS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

453304:ATC03 RS07585
gene id: 453304:ATC03_RS07585
uniprot id: A0A191WEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

453304:ATC03 RS13350
gene id: 453304:ATC03_RS13350
uniprot id: A0A191WH98
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

453304:ATC03 RS01715
gene id: 453304:ATC03_RS01715
uniprot id: A0A191WBU5
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

453304:ATC03 RS02900
gene id: 453304:ATC03_RS02900
uniprot id: A0A191WC64
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

453304:ATC03 RS09425
gene id: 453304:ATC03_RS09425
uniprot id: A0A191WFD8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

453304:ATC03 RS05095
gene id: 453304:ATC03_RS05095
uniprot id: A0A191WD47
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

453304:ATC03 RS16150
gene id: 453304:ATC03_RS16150
uniprot id: A0A191WIG8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS03770
gene id: 453304:ATC03_RS03770
uniprot id: A0A191WCJ2
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS19385
gene id: 453304:ATC03_RS19385
uniprot id: A0A191WJY4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

453304:ATC03 RS04290
gene id: 453304:ATC03_RS04290
uniprot id: A0A191WD11
names: Subcellular Location Annotation
messages: Cell membrane

453304:ATC03 RS00825
gene id: 453304:ATC03_RS00825
uniprot id: A0A191WBG6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

453304:ATC03 RS03370
gene id: 453304:ATC03_RS03370
uniprot id: A0A191WCD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS17065
gene id: 453304:ATC03_RS17065
uniprot id: A0A191WJ04
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

453304:ATC03 RS18805
gene id: 453304:ATC03_RS18805
uniprot id: A0A191WLG9
names: Similarity
messages: Belongs to the YciI family.

453304:ATC03 RS01690
gene id: 453304:ATC03_RS01690
uniprot id: A0A191WBN2
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS18105
gene id: 453304:ATC03_RS18105
uniprot id: A0A191WJ34
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

453304:ATC03 RS17275
gene id: 453304:ATC03_RS17275
uniprot id: A0A191WIV7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

453304:ATC03 RS09500
gene id: 453304:ATC03_RS09500
uniprot id: A0A191WKS4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

453304:ATC03 RS11860
gene id: 453304:ATC03_RS11860
uniprot id: A0A191WGL2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

453304:ATC03 RS06355
gene id: 453304:ATC03_RS06355
uniprot id: A0A191WKR3
names: Subcellular Location Annotation
messages: Cytoplasm

453304:ATC03 RS04620
gene id: 453304:ATC03_RS04620
uniprot id: A0A191WCX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

453304:ATC03 RS10010
gene id: 453304:ATC03_RS10010
uniprot id: A0A191WFP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS03100
gene id: 453304:ATC03_RS03100
uniprot id: A0A191WCH0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

453304:ATC03 RS19210
gene id: 453304:ATC03_RS19210
uniprot id: A0A191WJK0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

453304:ATC03 RS10180
gene id: 453304:ATC03_RS10180
uniprot id: A0A191WFK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

453304:ATC03 RS00175
gene id: 453304:ATC03_RS00175
uniprot id: A0A191WAY1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

453304:ATC03 RS07515
gene id: 453304:ATC03_RS07515
uniprot id: A0A191WEI5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

453304:ATC03 RS13520
gene id: 453304:ATC03_RS13520
uniprot id: A0A191WH39
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

453304:ATC03 RS19000
gene id: 453304:ATC03_RS19000
uniprot id: A0A191WJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS06735
gene id: 453304:ATC03_RS06735
uniprot id: A0A191WE40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

453304:ATC03 RS11135
gene id: 453304:ATC03_RS11135
uniprot id: A0A191WKY2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

453304:ATC03 RS10465
gene id: 453304:ATC03_RS10465
uniprot id: A0A191WFT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

453304:ATC03 RS06085
gene id: 453304:ATC03_RS06085
uniprot id: A0A191WDV2
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

453304:ATC03 RS01560
gene id: 453304:ATC03_RS01560
uniprot id: A0A191WBM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

453304:ATC03 RS10425
gene id: 453304:ATC03_RS10425
uniprot id: A0A191WFL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

453304:ATC03 RS11565
gene id: 453304:ATC03_RS11565
uniprot id: A0A191WGF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

453304:ATC03 RS17540
gene id: 453304:ATC03_RS17540
uniprot id: A0A191WJ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

453304:ATC03 RS08000
gene id: 453304:ATC03_RS08000
uniprot id: A0A191WEF5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS11840
gene id: 453304:ATC03_RS11840
uniprot id: A0A191WG86
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS08500
gene id: 453304:ATC03_RS08500
uniprot id: A0A191WEU6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

453304:ATC03 RS12390
gene id: 453304:ATC03_RS12390
uniprot id: A0A191WGK6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS14130
gene id: 453304:ATC03_RS14130
uniprot id: A0A191WHD9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

453304:ATC03 RS06685
gene id: 453304:ATC03_RS06685
uniprot id: A0A191WE58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS10005
gene id: 453304:ATC03_RS10005
uniprot id: A0A191WFK4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

453304:ATC03 RS12605
gene id: 453304:ATC03_RS12605
uniprot id: A0A191WGS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

453304:ATC03 RS00950
gene id: 453304:ATC03_RS00950
uniprot id: A0A191WBB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS17120
gene id: 453304:ATC03_RS17120
uniprot id: A0A191WIX6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS04625
gene id: 453304:ATC03_RS04625
uniprot id: A0A191WCY2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

453304:ATC03 RS00285
gene id: 453304:ATC03_RS00285
uniprot id: A0A191WB08
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

453304:ATC03 RS13525
gene id: 453304:ATC03_RS13525
uniprot id: A0A191WH78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

453304:ATC03 RS00025
gene id: 453304:ATC03_RS00025
uniprot id: A0A191WB42
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

453304:ATC03 RS11505
gene id: 453304:ATC03_RS11505
uniprot id: A0A191WGE4
names: Subcellular Location Annotation
messages: Cytoplasm

453304:ATC03 RS15660
gene id: 453304:ATC03_RS15660
uniprot id: A0A191WI01
names: Similarity
messages: Belongs to the proline racemase family.

453304:ATC03 RS06275
gene id: 453304:ATC03_RS06275
uniprot id: A0A191WDT2
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

453304:ATC03 RS09115
gene id: 453304:ATC03_RS09115
uniprot id: A0A191WEZ6
names: Similarity
messages: Belongs to the peptidase M1 family.

453304:ATC03 RS00270
gene id: 453304:ATC03_RS00270
uniprot id: A0A191WB61
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

453304:ATC03 RS01790
gene id: 453304:ATC03_RS01790
uniprot id: A0A191WBP7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

453304:ATC03 RS16720
gene id: 453304:ATC03_RS16720
uniprot id: A0A191WIV8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

453304:ATC03 RS09715
gene id: 453304:ATC03_RS09715
uniprot id: A0A191WFC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

453304:ATC03 RS10125
gene id: 453304:ATC03_RS10125
uniprot id: A0A191WFM4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS15210
gene id: 453304:ATC03_RS15210
uniprot id: A0A191WI11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

453304:ATC03 RS02125
gene id: 453304:ATC03_RS02125
uniprot id: A0A191WC14
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

453304:ATC03 RS03740
gene id: 453304:ATC03_RS03740
uniprot id: A0A191WCI7
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

453304:ATC03 RS10715
gene id: 453304:ATC03_RS10715
uniprot id: A0A191WL00
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

453304:ATC03 RS13905
gene id: 453304:ATC03_RS13905
uniprot id: A0A191WHI4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

453304:ATC03 RS16470
gene id: 453304:ATC03_RS16470
uniprot id: A0A191WIR5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS15305
gene id: 453304:ATC03_RS15305
uniprot id: A0A191WHU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

453304:ATC03 RS07220
gene id: 453304:ATC03_RS07220
uniprot id: A0A191WE37
names: Similarity
messages: Belongs to the FPG family.

453304:ATC03 RS13685
gene id: 453304:ATC03_RS13685
uniprot id: A0A191WH64
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

453304:ATC03 RS19300
gene id: 453304:ATC03_RS19300
uniprot id: A0A191WJT4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

453304:ATC03 RS09690
gene id: 453304:ATC03_RS09690
uniprot id: A0A191WFB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

453304:ATC03 RS09280
gene id: 453304:ATC03_RS09280
uniprot id: A0A191WF43
names: Similarity
messages: Belongs to the SufE family.

453304:ATC03 RS06455
gene id: 453304:ATC03_RS06455
uniprot id: A0A191WE18
names: Similarity
messages: Belongs to the UDPGP type 2 family.

453304:ATC03 RS15090
gene id: 453304:ATC03_RS15090
uniprot id: A0A191WL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

453304:ATC03 RS08650
gene id: 453304:ATC03_RS08650
uniprot id: A0A191WF14
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

453304:ATC03 RS02165
gene id: 453304:ATC03_RS02165
uniprot id: A0A191WBW3
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS18780
gene id: 453304:ATC03_RS18780
uniprot id: A0A191WJN9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

453304:ATC03 RS03060
gene id: 453304:ATC03_RS03060
uniprot id: A0A191WCG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

453304:ATC03 RS20850
gene id: 453304:ATC03_RS20850
uniprot id: A0A191WI79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

453304:ATC03 RS11115
gene id: 453304:ATC03_RS11115
uniprot id: A0A191WFX4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

453304:ATC03 RS13250
gene id: 453304:ATC03_RS13250
uniprot id: A0A191WH33
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS10315
gene id: 453304:ATC03_RS10315
uniprot id: A0A191WFU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

453304:ATC03 RS02500
gene id: 453304:ATC03_RS02500
uniprot id: A0A191WC74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS11245
gene id: 453304:ATC03_RS11245
uniprot id: A0A191WG93
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

453304:ATC03 RS15185
gene id: 453304:ATC03_RS15185
uniprot id: A0A191WI06
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

453304:ATC03 RS11450
gene id: 453304:ATC03_RS11450
uniprot id: A0A191WGC7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

453304:ATC03 RS09065
gene id: 453304:ATC03_RS09065
uniprot id: A0A191WF45
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

453304:ATC03 RS13625
gene id: 453304:ATC03_RS13625
uniprot id: A0A191WH54
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

453304:ATC03 RS00455
gene id: 453304:ATC03_RS00455
uniprot id: A0A191WBA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

453304:ATC03 RS14085
gene id: 453304:ATC03_RS14085
uniprot id: A0A191WHL4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

453304:ATC03 RS13830
gene id: 453304:ATC03_RS13830
uniprot id: A0A191WH51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

453304:ATC03 RS06845
gene id: 453304:ATC03_RS06845
uniprot id: A0A191WDY5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS13740
gene id: 453304:ATC03_RS13740
uniprot id: A0A191WHF7
names: Similarity
messages: Belongs to the peptidase S51 family.

453304:ATC03 RS01785
gene id: 453304:ATC03_RS01785
uniprot id: A0A191WBP6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

453304:ATC03 RS01615
gene id: 453304:ATC03_RS01615
uniprot id: A0A191WBL8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

453304:ATC03 RS16610
gene id: 453304:ATC03_RS16610
uniprot id: A0A191WIF1
names: Similarity
messages: Belongs to the YciI family.

453304:ATC03 RS12395
gene id: 453304:ATC03_RS12395
uniprot id: A0A191WGN9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

453304:ATC03 RS00465
gene id: 453304:ATC03_RS00465
uniprot id: A0A191WB26
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

453304:ATC03 RS12470
gene id: 453304:ATC03_RS12470
uniprot id: A0A191WL06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

453304:ATC03 RS16070
gene id: 453304:ATC03_RS16070
uniprot id: A0A191WIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS15275
gene id: 453304:ATC03_RS15275
uniprot id: A0A191WI65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

453304:ATC03 RS18665
gene id: 453304:ATC03_RS18665
uniprot id: A0A191WLJ0
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS11440
gene id: 453304:ATC03_RS11440
uniprot id: A0A191WG85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

453304:ATC03 RS00580
gene id: 453304:ATC03_RS00580
uniprot id: A0A191WB54
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS17135
gene id: 453304:ATC03_RS17135
uniprot id: A0A191WIM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS08630
gene id: 453304:ATC03_RS08630
uniprot id: A0A191WET0
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

453304:ATC03 RS09550
gene id: 453304:ATC03_RS09550
uniprot id: A0A191WF91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

453304:ATC03 RS05280
gene id: 453304:ATC03_RS05280
uniprot id: A0A191WDE1
names: Similarity
messages: Belongs to the HIBADH-related family.

453304:ATC03 RS09475
gene id: 453304:ATC03_RS09475
uniprot id: A0A191WFE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

453304:ATC03 RS01590
gene id: 453304:ATC03_RS01590
uniprot id: A0A191WBS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

453304:ATC03 RS16745
gene id: 453304:ATC03_RS16745
uniprot id: A0A191WIW1
names: Similarity
messages: Belongs to the YciI family.

453304:ATC03 RS12560
gene id: 453304:ATC03_RS12560
uniprot id: A0A191WGV3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

453304:ATC03 RS02285
gene id: 453304:ATC03_RS02285
uniprot id: A0A191WJY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS08410
gene id: 453304:ATC03_RS08410
uniprot id: A0A191WEP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

453304:ATC03 RS08540
gene id: 453304:ATC03_RS08540
uniprot id: A0A191WEY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

453304:ATC03 RS09640
gene id: 453304:ATC03_RS09640
uniprot id: A0A191WFI0
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

453304:ATC03 RS11345
gene id: 453304:ATC03_RS11345
uniprot id: A0A191WG69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

453304:ATC03 RS19660
gene id: 453304:ATC03_RS19660
uniprot id: A0A191WK27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

453304:ATC03 RS16260
gene id: 453304:ATC03_RS16260
uniprot id: A0A191WII8
names: Subcellular Location Annotation
messages: Cytoplasm

453304:ATC03 RS15300
gene id: 453304:ATC03_RS15300
uniprot id: A0A191WI70
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

453304:ATC03 RS13860
gene id: 453304:ATC03_RS13860
uniprot id: A0A191WH56
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

453304:ATC03 RS09195
gene id: 453304:ATC03_RS09195
uniprot id: A0A191WF28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

453304:ATC03 RS13535
gene id: 453304:ATC03_RS13535
uniprot id: A0A191WHC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

453304:ATC03 RS06210
gene id: 453304:ATC03_RS06210
uniprot id: A0A191WDM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

453304:ATC03 RS05860
gene id: 453304:ATC03_RS05860
uniprot id: A0A191WDL2
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS16270
gene id: 453304:ATC03_RS16270
uniprot id: A0A191WIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS02485
gene id: 453304:ATC03_RS02485
uniprot id: A0A191WC28
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

453304:ATC03 RS01695
gene id: 453304:ATC03_RS01695
uniprot id: A0A191WJW9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09730
gene id: 453304:ATC03_RS09730
uniprot id: A0A191WFK1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS16345
gene id: 453304:ATC03_RS16345
uniprot id: A0A191WIK3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

453304:ATC03 RS13575
gene id: 453304:ATC03_RS13575
uniprot id: A0A191WL35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS11055
gene id: 453304:ATC03_RS11055
uniprot id: A0A191WFZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

453304:ATC03 RS11640
gene id: 453304:ATC03_RS11640
uniprot id: A0A191WG96
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

453304:ATC03 RS19025
gene id: 453304:ATC03_RS19025
uniprot id: A0A191WJN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

453304:ATC03 RS17990
gene id: 453304:ATC03_RS17990
uniprot id: A0A191WJB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

453304:ATC03 RS03830
gene id: 453304:ATC03_RS03830
uniprot id: A0A191WCK2
names: Similarity
messages: Belongs to the YoeB family.

453304:ATC03 RS05510
gene id: 453304:ATC03_RS05510
uniprot id: A0A191WDI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS10310
gene id: 453304:ATC03_RS10310
uniprot id: A0A191WFQ4
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

453304:ATC03 RS08420
gene id: 453304:ATC03_RS08420
uniprot id: A0A191WEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

453304:ATC03 RS15260
gene id: 453304:ATC03_RS15260
uniprot id: A0A191WHX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

453304:ATC03 RS09135
gene id: 453304:ATC03_RS09135
uniprot id: A0A191WFA3
names: Similarity
messages: Belongs to the FPG family.

453304:ATC03 RS05180
gene id: 453304:ATC03_RS05180
uniprot id: A0A191WKN6
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

453304:ATC03 RS09820
gene id: 453304:ATC03_RS09820
uniprot id: A0A191WFE1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

453304:ATC03 RS09250
gene id: 453304:ATC03_RS09250
uniprot id: A0A191WKX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

453304:ATC03 RS12575
gene id: 453304:ATC03_RS12575
uniprot id: A0A191WGN1
names: Similarity
messages: Belongs to the FPG family.

453304:ATC03 RS06535
gene id: 453304:ATC03_RS06535
uniprot id: A0A191WE04
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS05135
gene id: 453304:ATC03_RS05135
uniprot id: A0A191WD65
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

453304:ATC03 RS05565
gene id: 453304:ATC03_RS05565
uniprot id: A0A191WDC3
names: Similarity
messages: Belongs to the thymidine kinase family.

453304:ATC03 RS09590
gene id: 453304:ATC03_RS09590
uniprot id: A0A191WFG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS02480
gene id: 453304:ATC03_RS02480
uniprot id: A0A191WC07
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

453304:ATC03 RS18010
gene id: 453304:ATC03_RS18010
uniprot id: A0A191WJ83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

453304:ATC03 RS12705
gene id: 453304:ATC03_RS12705
uniprot id: A0A191WGX8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS11500
gene id: 453304:ATC03_RS11500
uniprot id: A0A191WL26
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS01665
gene id: 453304:ATC03_RS01665
uniprot id: A0A191WBM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

453304:ATC03 RS07335
gene id: 453304:ATC03_RS07335
uniprot id: A0A191WED7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS02850
gene id: 453304:ATC03_RS02850
uniprot id: A0A191WC75
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

453304:ATC03 RS02325
gene id: 453304:ATC03_RS02325
uniprot id: A0A191WC48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS05305
gene id: 453304:ATC03_RS05305
uniprot id: A0A191WD91
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

453304:ATC03 RS06440
gene id: 453304:ATC03_RS06440
uniprot id: A0A191WDR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

453304:ATC03 RS00700
gene id: 453304:ATC03_RS00700
uniprot id: A0A191WB72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

453304:ATC03 RS18305
gene id: 453304:ATC03_RS18305
uniprot id: A0A191WJL9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

453304:ATC03 RS01040
gene id: 453304:ATC03_RS01040
uniprot id: A0A191WBJ4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

453304:ATC03 RS19235
gene id: 453304:ATC03_RS19235
uniprot id: A0A191WJK4
names: Similarity
messages: Belongs to the catalase family.

453304:ATC03 RS09045
gene id: 453304:ATC03_RS09045
uniprot id: A0A191WF77
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

453304:ATC03 RS18410
gene id: 453304:ATC03_RS18410
uniprot id: A0A191WJE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS10410
gene id: 453304:ATC03_RS10410
uniprot id: A0A191WFS4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

453304:ATC03 RS10260
gene id: 453304:ATC03_RS10260
uniprot id: A0A191WFP4
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS12665
gene id: 453304:ATC03_RS12665
uniprot id: A0A191WGS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

453304:ATC03 RS06205
gene id: 453304:ATC03_RS06205
uniprot id: A0A191WDM1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

453304:ATC03 RS06170
gene id: 453304:ATC03_RS06170
uniprot id: A0A191WDW7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

453304:ATC03 RS21195
gene id: 453304:ATC03_RS21195
uniprot id: A0A191WFJ8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

453304:ATC03 RS09525
gene id: 453304:ATC03_RS09525
uniprot id: A0A191WFC0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS00235
gene id: 453304:ATC03_RS00235
uniprot id: A0A191WAZ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

453304:ATC03 RS15270
gene id: 453304:ATC03_RS15270
uniprot id: A0A191WI69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

453304:ATC03 RS15220
gene id: 453304:ATC03_RS15220
uniprot id: A0A191WI55
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

453304:ATC03 RS05320
gene id: 453304:ATC03_RS05320
uniprot id: A0A191WDE6
names: Similarity
messages: Belongs to the AHA1 family.

453304:ATC03 RS04600
gene id: 453304:ATC03_RS04600
uniprot id: A0A191WK73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS16340
gene id: 453304:ATC03_RS16340
uniprot id: A0A191WIF9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

453304:ATC03 RS09005
gene id: 453304:ATC03_RS09005
uniprot id: A0A191WEZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

453304:ATC03 RS07785
gene id: 453304:ATC03_RS07785
uniprot id: A0A191WEC1
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS02145
gene id: 453304:ATC03_RS02145
uniprot id: A0A191WBX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

453304:ATC03 RS11815
gene id: 453304:ATC03_RS11815
uniprot id: A0A191WGC1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

453304:ATC03 RS00065
gene id: 453304:ATC03_RS00065
uniprot id: A0A191WB25
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

453304:ATC03 RS10765
gene id: 453304:ATC03_RS10765
uniprot id: A0A191WFS0
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS12850
gene id: 453304:ATC03_RS12850
uniprot id: A0A191WL37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

453304:ATC03 RS02640
gene id: 453304:ATC03_RS02640
uniprot id: A0A191WCA6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

453304:ATC03 RS08315
gene id: 453304:ATC03_RS08315
uniprot id: A0A191WEV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

453304:ATC03 RS13300
gene id: 453304:ATC03_RS13300
uniprot id: A0A191WH04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

453304:ATC03 RS13120
gene id: 453304:ATC03_RS13120
uniprot id: A0A191WGX5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS12145
gene id: 453304:ATC03_RS12145
uniprot id: A0A191WGH2
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09620
gene id: 453304:ATC03_RS09620
uniprot id: A0A191WFI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

453304:ATC03 RS08340
gene id: 453304:ATC03_RS08340
uniprot id: A0A191WER3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

453304:ATC03 RS15135
gene id: 453304:ATC03_RS15135
uniprot id: A0A191WI41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

453304:ATC03 RS09460
gene id: 453304:ATC03_RS09460
uniprot id: A0A191WF51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

453304:ATC03 RS18900
gene id: 453304:ATC03_RS18900
uniprot id: A0A191WJE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

453304:ATC03 RS14695
gene id: 453304:ATC03_RS14695
uniprot id: A0A191WHJ9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS17815
gene id: 453304:ATC03_RS17815
uniprot id: A0A191WJ92
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

453304:ATC03 RS15340
gene id: 453304:ATC03_RS15340
uniprot id: A0A191WI37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

453304:ATC03 RS13180
gene id: 453304:ATC03_RS13180
uniprot id: A0A191WGU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS04590
gene id: 453304:ATC03_RS04590
uniprot id: A0A191WKJ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

453304:ATC03 RS05525
gene id: 453304:ATC03_RS05525
uniprot id: A0A191WKM1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

453304:ATC03 RS11190
gene id: 453304:ATC03_RS11190
uniprot id: A0A191WKW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

453304:ATC03 RS11355
gene id: 453304:ATC03_RS11355
uniprot id: A0A191WGB5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

453304:ATC03 RS08105
gene id: 453304:ATC03_RS08105
uniprot id: A0A191WES0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

453304:ATC03 RS06865
gene id: 453304:ATC03_RS06865
uniprot id: A0A191WDY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

453304:ATC03 RS10405
gene id: 453304:ATC03_RS10405
uniprot id: A0A191WFP2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

453304:ATC03 RS10075
gene id: 453304:ATC03_RS10075
uniprot id: A0A191WFF7
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS16845
gene id: 453304:ATC03_RS16845
uniprot id: A0A191WIX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS00275
gene id: 453304:ATC03_RS00275
uniprot id: A0A191WB76
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

453304:ATC03 RS09080
gene id: 453304:ATC03_RS09080
uniprot id: A0A191WKR6
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

453304:ATC03 RS11305
gene id: 453304:ATC03_RS11305
uniprot id: A0A191WKY7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

453304:ATC03 RS06160
gene id: 453304:ATC03_RS06160
uniprot id: A0A191WDR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

453304:ATC03 RS19635
gene id: 453304:ATC03_RS19635
uniprot id: A0A191WK62
names: Similarity
messages: Belongs to the ParB family.

453304:ATC03 RS07015
gene id: 453304:ATC03_RS07015
uniprot id: A0A191WE84
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

453304:ATC03 RS19585
gene id: 453304:ATC03_RS19585
uniprot id: A0A191WK17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

453304:ATC03 RS06605
gene id: 453304:ATC03_RS06605
uniprot id: A0A191WDZ1
names: Similarity
messages: Belongs to the peptidase M18 family.

453304:ATC03 RS11720
gene id: 453304:ATC03_RS11720
uniprot id: A0A191WGH5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

453304:ATC03 RS06425
gene id: 453304:ATC03_RS06425
uniprot id: A0A191WE13
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

453304:ATC03 RS12630
gene id: 453304:ATC03_RS12630
uniprot id: A0A191WGP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

453304:ATC03 RS08385
gene id: 453304:ATC03_RS08385
uniprot id: A0A191WEN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

453304:ATC03 RS16035
gene id: 453304:ATC03_RS16035
uniprot id: A0A191WI53
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

453304:ATC03 RS11550
gene id: 453304:ATC03_RS11550
uniprot id: A0A191WGA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

453304:ATC03 RS04425
gene id: 453304:ATC03_RS04425
uniprot id: A0A191WCU7
names: Function
names: Similarity
messages: Belongs to the chloramphenicol acetyltransferase family.
messages: This enzyme is an effector of chloramphenicol resistance in bacteria.

453304:ATC03 RS10390
gene id: 453304:ATC03_RS10390
uniprot id: A0A191WFW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

453304:ATC03 RS06770
gene id: 453304:ATC03_RS06770
uniprot id: A0A191WE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS06870
gene id: 453304:ATC03_RS06870
uniprot id: A0A191WDZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

453304:ATC03 RS19595
gene id: 453304:ATC03_RS19595
uniprot id: A0A191WK59
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

453304:ATC03 RS01595
gene id: 453304:ATC03_RS01595
uniprot id: A0A191WBT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

453304:ATC03 RS15235
gene id: 453304:ATC03_RS15235
uniprot id: A0A191WHX2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

453304:ATC03 RS02565
gene id: 453304:ATC03_RS02565
uniprot id: A0A191WC83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

453304:ATC03 RS00555
gene id: 453304:ATC03_RS00555
uniprot id: A0A191WB41
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

453304:ATC03 RS09710
gene id: 453304:ATC03_RS09710
uniprot id: A0A191WF95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

453304:ATC03 RS11600
gene id: 453304:ATC03_RS11600
uniprot id: A0A191WGH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

453304:ATC03 RS11930
gene id: 453304:ATC03_RS11930
uniprot id: A0A191WGL0
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

453304:ATC03 RS15495
gene id: 453304:ATC03_RS15495
uniprot id: A0A191WLA4
names: Similarity
messages: Belongs to the GSP E family.

453304:ATC03 RS02845
gene id: 453304:ATC03_RS02845
uniprot id: A0A191WC54
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

453304:ATC03 RS13600
gene id: 453304:ATC03_RS13600
uniprot id: A0A191WH87
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

453304:ATC03 RS19675
gene id: 453304:ATC03_RS19675
uniprot id: A0A191WK80
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

453304:ATC03 RS13075
gene id: 453304:ATC03_RS13075
uniprot id: A0A191WH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

453304:ATC03 RS02530
gene id: 453304:ATC03_RS02530
uniprot id: A0A191WC32
names: Similarity
messages: Belongs to the PstS family.

453304:ATC03 RS06745
gene id: 453304:ATC03_RS06745
uniprot id: A0A191WKS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

453304:ATC03 RS16905
gene id: 453304:ATC03_RS16905
uniprot id: A0A191WIU6
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

453304:ATC03 RS14405
gene id: 453304:ATC03_RS14405
uniprot id: A0A191WHM2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

453304:ATC03 RS14520
gene id: 453304:ATC03_RS14520
uniprot id: A0A191WHK3
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS00220
gene id: 453304:ATC03_RS00220
uniprot id: A0A191WB70
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

453304:ATC03 RS15060
gene id: 453304:ATC03_RS15060
uniprot id: A0A191WHU3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

453304:ATC03 RS19575
gene id: 453304:ATC03_RS19575
uniprot id: A0A191WJR7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

453304:ATC03 RS19615
gene id: 453304:ATC03_RS19615
uniprot id: A0A191WJZ8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

453304:ATC03 RS09840
gene id: 453304:ATC03_RS09840
uniprot id: A0A191WFB9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

453304:ATC03 RS00375
gene id: 453304:ATC03_RS00375
uniprot id: A0A191WB10
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

453304:ATC03 RS11685
gene id: 453304:ATC03_RS11685
uniprot id: A0A191WGG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

453304:ATC03 RS13290
gene id: 453304:ATC03_RS13290
uniprot id: A0A191WH80
names: Similarity
messages: Belongs to the Nth/MutY family.

453304:ATC03 RS07840
gene id: 453304:ATC03_RS07840
uniprot id: A0A191WED0
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09085
gene id: 453304:ATC03_RS09085
uniprot id: A0A191WEZ1
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

453304:ATC03 RS14245
gene id: 453304:ATC03_RS14245
uniprot id: A0A191WHF9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

453304:ATC03 RS12760
gene id: 453304:ATC03_RS12760
uniprot id: A0A191WGZ8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

453304:ATC03 RS14650
gene id: 453304:ATC03_RS14650
uniprot id: A0A191WHR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

453304:ATC03 RS01770
gene id: 453304:ATC03_RS01770
uniprot id: A0A191WBR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

453304:ATC03 RS16145
gene id: 453304:ATC03_RS16145
uniprot id: A0A191WIC5
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

453304:ATC03 RS15790
gene id: 453304:ATC03_RS15790
uniprot id: A0A191WI71
names: Similarity
messages: Belongs to the pirin family.

453304:ATC03 RS17245
gene id: 453304:ATC03_RS17245
uniprot id: A0A191WLF4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

453304:ATC03 RS07710
gene id: 453304:ATC03_RS07710
uniprot id: A0A191WEJ4
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS02270
gene id: 453304:ATC03_RS02270
uniprot id: A0A191WBZ9
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

453304:ATC03 RS07695
gene id: 453304:ATC03_RS07695
uniprot id: A0A191WEA7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

453304:ATC03 RS12805
gene id: 453304:ATC03_RS12805
uniprot id: A0A191WGM9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

453304:ATC03 RS05375
gene id: 453304:ATC03_RS05375
uniprot id: A0A191WD88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

453304:ATC03 RS17800
gene id: 453304:ATC03_RS17800
uniprot id: A0A191WJD2
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS02250
gene id: 453304:ATC03_RS02250
uniprot id: A0A191WBX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

453304:ATC03 RS06235
gene id: 453304:ATC03_RS06235
uniprot id: A0A191WDN2
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS06885
gene id: 453304:ATC03_RS06885
uniprot id: A0A191WKN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

453304:ATC03 RS13065
gene id: 453304:ATC03_RS13065
uniprot id: A0A191WGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

453304:ATC03 RS11540
gene id: 453304:ATC03_RS11540
uniprot id: A0A191WG44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

453304:ATC03 RS07575
gene id: 453304:ATC03_RS07575
uniprot id: A0A191WEE1
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09445
gene id: 453304:ATC03_RS09445
uniprot id: A0A191WFA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

453304:ATC03 RS17330
gene id: 453304:ATC03_RS17330
uniprot id: A0A191WIQ6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS07160
gene id: 453304:ATC03_RS07160
uniprot id: A0A191WE27
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

453304:ATC03 RS11835
gene id: 453304:ATC03_RS11835
uniprot id: A0A191WGI8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS13255
gene id: 453304:ATC03_RS13255
uniprot id: A0A191WH82
names: Similarity
messages: Belongs to the ribF family.

453304:ATC03 RS13680
gene id: 453304:ATC03_RS13680
uniprot id: A0A191WH26
names: Similarity
messages: Belongs to the arginase family.

453304:ATC03 RS14725
gene id: 453304:ATC03_RS14725
uniprot id: A0A191WHX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS14820
gene id: 453304:ATC03_RS14820
uniprot id: A0A191WHQ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

453304:ATC03 RS04120
gene id: 453304:ATC03_RS04120
uniprot id: A0A191WCS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS00980
gene id: 453304:ATC03_RS00980
uniprot id: A0A191WBD9
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

453304:ATC03 RS08455
gene id: 453304:ATC03_RS08455
uniprot id: A0A191WEW7
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

453304:ATC03 RS17895
gene id: 453304:ATC03_RS17895
uniprot id: A0A191WJE6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS10945
gene id: 453304:ATC03_RS10945
uniprot id: A0A191WG62
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

453304:ATC03 RS05795
gene id: 453304:ATC03_RS05795
uniprot id: A0A191WDQ6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

453304:ATC03 RS16365
gene id: 453304:ATC03_RS16365
uniprot id: A0A191WIB1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

453304:ATC03 RS13240
gene id: 453304:ATC03_RS13240
uniprot id: A0A191WGZ5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

453304:ATC03 RS01555
gene id: 453304:ATC03_RS01555
uniprot id: A0A191WBK8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS12650
gene id: 453304:ATC03_RS12650
uniprot id: A0A191WGK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS05975
gene id: 453304:ATC03_RS05975
uniprot id: A0A191WDI2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

453304:ATC03 RS14265
gene id: 453304:ATC03_RS14265
uniprot id: A0A191WHC6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

453304:ATC03 RS15800
gene id: 453304:ATC03_RS15800
uniprot id: A0A191WLB3
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS19590
gene id: 453304:ATC03_RS19590
uniprot id: A0A191WK71
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS12355
gene id: 453304:ATC03_RS12355
uniprot id: A0A191WGG1
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

453304:ATC03 RS15345
gene id: 453304:ATC03_RS15345
uniprot id: A0A191WI86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

453304:ATC03 RS10955
gene id: 453304:ATC03_RS10955
uniprot id: A0A191WFU9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS13640
gene id: 453304:ATC03_RS13640
uniprot id: A0A191WHD7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

453304:ATC03 RS00515
gene id: 453304:ATC03_RS00515
uniprot id: A0A191WB44
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

453304:ATC03 RS09035
gene id: 453304:ATC03_RS09035
uniprot id: A0A191WF03
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS16220
gene id: 453304:ATC03_RS16220
uniprot id: A0A191WIE0
names: Subcellular Location Annotation
messages: Cytoplasm

453304:ATC03 RS16310
gene id: 453304:ATC03_RS16310
uniprot id: A0A191WIJ8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09355
gene id: 453304:ATC03_RS09355
uniprot id: A0A191WF31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

453304:ATC03 RS11710
gene id: 453304:ATC03_RS11710
uniprot id: A0A191WGJ4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

453304:ATC03 RS07310
gene id: 453304:ATC03_RS07310
uniprot id: A0A191WED2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

453304:ATC03 RS15240
gene id: 453304:ATC03_RS15240
uniprot id: A0A191WI17
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

453304:ATC03 RS10485
gene id: 453304:ATC03_RS10485
uniprot id: A0A191WFM6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

453304:ATC03 RS14660
gene id: 453304:ATC03_RS14660
uniprot id: A0A191WHW4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

453304:ATC03 RS17650
gene id: 453304:ATC03_RS17650
uniprot id: A0A191WJ63
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

453304:ATC03 RS18550
gene id: 453304:ATC03_RS18550
uniprot id: A0A191WJQ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

453304:ATC03 RS09555
gene id: 453304:ATC03_RS09555
uniprot id: A0A191WFC5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS11280
gene id: 453304:ATC03_RS11280
uniprot id: A0A191WFZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

453304:ATC03 RS05285
gene id: 453304:ATC03_RS05285
uniprot id: A0A191WDG9
names: Similarity
messages: Belongs to the TPP enzyme family.

453304:ATC03 RS09400
gene id: 453304:ATC03_RS09400
uniprot id: A0A191WFD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

453304:ATC03 RS08480
gene id: 453304:ATC03_RS08480
uniprot id: A0A191WEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

453304:ATC03 RS19310
gene id: 453304:ATC03_RS19310
uniprot id: A0A191WK34
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09910
gene id: 453304:ATC03_RS09910
uniprot id: A0A191WFJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

453304:ATC03 RS05120
gene id: 453304:ATC03_RS05120
uniprot id: A0A191WDE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS09685
gene id: 453304:ATC03_RS09685
uniprot id: A0A191WF89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

453304:ATC03 RS06165
gene id: 453304:ATC03_RS06165
uniprot id: A0A191WDT5
names: Similarity
messages: Belongs to the PstS family.

453304:ATC03 RS13940
gene id: 453304:ATC03_RS13940
uniprot id: A0A191WHI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

453304:ATC03 RS12915
gene id: 453304:ATC03_RS12915
uniprot id: A0A191WGQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

453304:ATC03 RS12720
gene id: 453304:ATC03_RS12720
uniprot id: A0A191WGL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

453304:ATC03 RS10335
gene id: 453304:ATC03_RS10335
uniprot id: A0A191WFQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

453304:ATC03 RS12020
gene id: 453304:ATC03_RS12020
uniprot id: A0A191WGM6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS06310
gene id: 453304:ATC03_RS06310
uniprot id: A0A191WDZ2
names: Similarity
messages: Belongs to the WXG100 family.

453304:ATC03 RS18080
gene id: 453304:ATC03_RS18080
uniprot id: A0A191WJD4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

453304:ATC03 RS12490
gene id: 453304:ATC03_RS12490
uniprot id: A0A191WGV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS14015
gene id: 453304:ATC03_RS14015
uniprot id: A0A191WHF6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

453304:ATC03 RS03585
gene id: 453304:ATC03_RS03585
uniprot id: A0A191WCN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

453304:ATC03 RS10165
gene id: 453304:ATC03_RS10165
uniprot id: A0A191WKT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

453304:ATC03 RS09245
gene id: 453304:ATC03_RS09245
uniprot id: A0A191WF16
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

453304:ATC03 RS09545
gene id: 453304:ATC03_RS09545
uniprot id: A0A191WF66
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS14270
gene id: 453304:ATC03_RS14270
uniprot id: A0A191WL50
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

453304:ATC03 RS01355
gene id: 453304:ATC03_RS01355
uniprot id: A0A191WBN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

453304:ATC03 RS04945
gene id: 453304:ATC03_RS04945
uniprot id: A0A191WD69
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

453304:ATC03 RS11370
gene id: 453304:ATC03_RS11370
uniprot id: A0A191WG74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

453304:ATC03 RS00670
gene id: 453304:ATC03_RS00670
uniprot id: A0A191WB65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

453304:ATC03 RS09700
gene id: 453304:ATC03_RS09700
uniprot id: A0A191WFI9
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

453304:ATC03 RS14495
gene id: 453304:ATC03_RS14495
uniprot id: A0A191WHN9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

453304:ATC03 RS09755
gene id: 453304:ATC03_RS09755
uniprot id: A0A191WFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

453304:ATC03 RS02225
gene id: 453304:ATC03_RS02225
uniprot id: A0A191WBX3
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

453304:ATC03 RS07075
gene id: 453304:ATC03_RS07075
uniprot id: A0A191WE67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

453304:ATC03 RS00645
gene id: 453304:ATC03_RS00645
uniprot id: A0A191WB60
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

453304:ATC03 RS10540
gene id: 453304:ATC03_RS10540
uniprot id: A0A191WFY9
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

453304:ATC03 RS05110
gene id: 453304:ATC03_RS05110
uniprot id: A0A191WDB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

453304:ATC03 RS19050
gene id: 453304:ATC03_RS19050
uniprot id: A0A191WJH1
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

453304:ATC03 RS08405
gene id: 453304:ATC03_RS08405
uniprot id: A0A191WEM9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

453304:ATC03 RS17845
gene id: 453304:ATC03_RS17845
uniprot id: A0A191WJ97
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS14490
gene id: 453304:ATC03_RS14490
uniprot id: A0A191WHJ8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

453304:ATC03 RS05225
gene id: 453304:ATC03_RS05225
uniprot id: A0A191WDG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

453304:ATC03 RS06895
gene id: 453304:ATC03_RS06895
uniprot id: A0A191WE93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

453304:ATC03 RS05830
gene id: 453304:ATC03_RS05830
uniprot id: A0A191WKK9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

453304:ATC03 RS12635
gene id: 453304:ATC03_RS12635
uniprot id: A0A191WGS4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

453304:ATC03 RS13420
gene id: 453304:ATC03_RS13420
uniprot id: A0A191WHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS07305
gene id: 453304:ATC03_RS07305
uniprot id: A0A191WEA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

453304:ATC03 RS09725
gene id: 453304:ATC03_RS09725
uniprot id: A0A191WFJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

453304:ATC03 RS18785
gene id: 453304:ATC03_RS18785
uniprot id: A0A191WJU8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

453304:ATC03 RS15095
gene id: 453304:ATC03_RS15095
uniprot id: A0A191WHU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

453304:ATC03 RS09580
gene id: 453304:ATC03_RS09580
uniprot id: A0A191WF96
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

453304:ATC03 RS08310
gene id: 453304:ATC03_RS08310
uniprot id: A0A191WEU2
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

453304:ATC03 RS08415
gene id: 453304:ATC03_RS08415
uniprot id: A0A191WES7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

453304:ATC03 RS05380
gene id: 453304:ATC03_RS05380
uniprot id: A0A191WDA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

453304:ATC03 RS08010
gene id: 453304:ATC03_RS08010
uniprot id: A0A191WEK9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

453304:ATC03 RS08125
gene id: 453304:ATC03_RS08125
uniprot id: A0A191WER2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS18425
gene id: 453304:ATC03_RS18425
uniprot id: A0A191WJN8
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

453304:ATC03 RS06820
gene id: 453304:ATC03_RS06820
uniprot id: A0A191WE55
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS15875
gene id: 453304:ATC03_RS15875
uniprot id: A0A191WIH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

453304:ATC03 RS14435
gene id: 453304:ATC03_RS14435
uniprot id: A0A191WHS5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

453304:ATC03 RS06545
gene id: 453304:ATC03_RS06545
uniprot id: A0A191WDS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

453304:ATC03 RS12345
gene id: 453304:ATC03_RS12345
uniprot id: A0A191WGS5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

453304:ATC03 RS01540
gene id: 453304:ATC03_RS01540
uniprot id: A0A191WBR4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

453304:ATC03 RS17655
gene id: 453304:ATC03_RS17655
uniprot id: A0A191WJB1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

453304:ATC03 RS19480
gene id: 453304:ATC03_RS19480
uniprot id: A0A191WK61
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

453304:ATC03 RS10305
gene id: 453304:ATC03_RS10305
uniprot id: A0A191WFM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS04485
gene id: 453304:ATC03_RS04485
uniprot id: A0A191WCW2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

453304:ATC03 RS16325
gene id: 453304:ATC03_RS16325
uniprot id: A0A191WIP5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

453304:ATC03 RS10515
gene id: 453304:ATC03_RS10515
uniprot id: A0A191WKU1
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

453304:ATC03 RS00145
gene id: 453304:ATC03_RS00145
uniprot id: A0A191WAY3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

453304:ATC03 RS14045
gene id: 453304:ATC03_RS14045
uniprot id: A0A191WHG1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

453304:ATC03 RS02320
gene id: 453304:ATC03_RS02320
uniprot id: A0A191WKD9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS16895
gene id: 453304:ATC03_RS16895
uniprot id: A0A191WIJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

453304:ATC03 RS03125
gene id: 453304:ATC03_RS03125
uniprot id: A0A191WCH6
names: Similarity
messages: Belongs to the YciI family.

453304:ATC03 RS09795
gene id: 453304:ATC03_RS09795
uniprot id: A0A191WFD6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

453304:ATC03 RS07345
gene id: 453304:ATC03_RS07345
uniprot id: A0A191WE57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

453304:ATC03 RS12735
gene id: 453304:ATC03_RS12735
uniprot id: A0A191WGZ4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

453304:ATC03 RS19105
gene id: 453304:ATC03_RS19105
uniprot id: A0A191WJI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS10025
gene id: 453304:ATC03_RS10025
uniprot id: A0A191WFH8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

453304:ATC03 RS09205
gene id: 453304:ATC03_RS09205
uniprot id: A0A191WF65
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

453304:ATC03 RS15325
gene id: 453304:ATC03_RS15325
uniprot id: A0A191WI76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

453304:ATC03 RS01090
gene id: 453304:ATC03_RS01090
uniprot id: A0A191WBL2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

453304:ATC03 RS09895
gene id: 453304:ATC03_RS09895
uniprot id: A0A191WFN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

453304:ATC03 RS07705
gene id: 453304:ATC03_RS07705
uniprot id: A0A191WEG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

453304:ATC03 RS02110
gene id: 453304:ATC03_RS02110
uniprot id: A0A191WBU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

453304:ATC03 RS15070
gene id: 453304:ATC03_RS15070
uniprot id: A0A191WI35
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS10175
gene id: 453304:ATC03_RS10175
uniprot id: A0A191WFH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS18530
gene id: 453304:ATC03_RS18530
uniprot id: A0A191WJ95
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

453304:ATC03 RS18025
gene id: 453304:ATC03_RS18025
uniprot id: A0A191WJH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

453304:ATC03 RS08155
gene id: 453304:ATC03_RS08155
uniprot id: A0A191WER7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

453304:ATC03 RS11095
gene id: 453304:ATC03_RS11095
uniprot id: A0A191WG33
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

453304:ATC03 RS03630
gene id: 453304:ATC03_RS03630
uniprot id: A0A191WCH2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

453304:ATC03 RS11525
gene id: 453304:ATC03_RS11525
uniprot id: A0A191WGA3
names: Similarity
messages: Belongs to the YggT family.

453304:ATC03 RS10695
gene id: 453304:ATC03_RS10695
uniprot id: A0A191WG16
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

453304:ATC03 RS07700
gene id: 453304:ATC03_RS07700
uniprot id: A0A191WEB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

453304:ATC03 RS01720
gene id: 453304:ATC03_RS01720
uniprot id: A0A191WBV8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

453304:ATC03 RS08775
gene id: 453304:ATC03_RS08775
uniprot id: A0A191WEZ0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

453304:ATC03 RS08635
gene id: 453304:ATC03_RS08635
uniprot id: A0A191WEW9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

453304:ATC03 RS09510
gene id: 453304:ATC03_RS09510
uniprot id: A0A191WFG1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS13315
gene id: 453304:ATC03_RS13315
uniprot id: A0A191WH94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS01765
gene id: 453304:ATC03_RS01765
uniprot id: A0A191WBP2
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS01585
gene id: 453304:ATC03_RS01585
uniprot id: A0A191WBN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

453304:ATC03 RS13200
gene id: 453304:ATC03_RS13200
uniprot id: A0A191WH65
names: Similarity
messages: Belongs to the CsoR family.

453304:ATC03 RS13790
gene id: 453304:ATC03_RS13790
uniprot id: A0A191WHG8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS06045
gene id: 453304:ATC03_RS06045
uniprot id: A0A191WDP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

453304:ATC03 RS09505
gene id: 453304:ATC03_RS09505
uniprot id: A0A191WFF4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

453304:ATC03 RS10700
gene id: 453304:ATC03_RS10700
uniprot id: A0A191WFR0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

453304:ATC03 RS12655
gene id: 453304:ATC03_RS12655
uniprot id: A0A191WGP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

453304:ATC03 RS05930
gene id: 453304:ATC03_RS05930
uniprot id: A0A191WDM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS17315
gene id: 453304:ATC03_RS17315
uniprot id: A0A191WJ48
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

453304:ATC03 RS14535
gene id: 453304:ATC03_RS14535
uniprot id: A0A191WKZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

453304:ATC03 RS08090
gene id: 453304:ATC03_RS08090
uniprot id: A0A191WEH9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

453304:ATC03 RS12770
gene id: 453304:ATC03_RS12770
uniprot id: A0A191WL17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

453304:ATC03 RS06040
gene id: 453304:ATC03_RS06040
uniprot id: A0A191WDJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS17525
gene id: 453304:ATC03_RS17525
uniprot id: A0A191WJ84
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

453304:ATC03 RS12475
gene id: 453304:ATC03_RS12475
uniprot id: A0A191WGL6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

453304:ATC03 RS12125
gene id: 453304:ATC03_RS12125
uniprot id: A0A191WGJ9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09775
gene id: 453304:ATC03_RS09775
uniprot id: A0A191WFK5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS19620
gene id: 453304:ATC03_RS19620
uniprot id: A0A191WK22
names: Similarity
messages: Belongs to the thioredoxin family.

453304:ATC03 RS07660
gene id: 453304:ATC03_RS07660
uniprot id: A0A191WEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS17725
gene id: 453304:ATC03_RS17725
uniprot id: A0A191WIX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

453304:ATC03 RS03435
gene id: 453304:ATC03_RS03435
uniprot id: A0A191WCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

453304:ATC03 RS10365
gene id: 453304:ATC03_RS10365
uniprot id: A0A191WFV8
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

453304:ATC03 RS09430
gene id: 453304:ATC03_RS09430
uniprot id: A0A191WFE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

453304:ATC03 RS14805
gene id: 453304:ATC03_RS14805
uniprot id: A0A191WHY8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

453304:ATC03 RS08255
gene id: 453304:ATC03_RS08255
uniprot id: A0A191WET3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

453304:ATC03 RS18700
gene id: 453304:ATC03_RS18700
uniprot id: A0A191WLA3
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS15190
gene id: 453304:ATC03_RS15190
uniprot id: A0A191WI54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

453304:ATC03 RS02800
gene id: 453304:ATC03_RS02800
uniprot id: A0A191WC49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

453304:ATC03 RS16180
gene id: 453304:ATC03_RS16180
uniprot id: A0A191WIM0
names: Similarity
messages: Belongs to the AHA1 family.

453304:ATC03 RS15665
gene id: 453304:ATC03_RS15665
uniprot id: A0A191WI51
names: Similarity
messages: Belongs to the DapA family.

453304:ATC03 RS12875
gene id: 453304:ATC03_RS12875
uniprot id: A0A191WGW6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

453304:ATC03 RS08525
gene id: 453304:ATC03_RS08525
uniprot id: A0A191WEQ2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

453304:ATC03 RS14330
gene id: 453304:ATC03_RS14330
uniprot id: A0A191WHD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

453304:ATC03 RS15150
gene id: 453304:ATC03_RS15150
uniprot id: A0A191WI00
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS06985
gene id: 453304:ATC03_RS06985
uniprot id: A0A191WE80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS09660
gene id: 453304:ATC03_RS09660
uniprot id: A0A191WF85
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

453304:ATC03 RS06240
gene id: 453304:ATC03_RS06240
uniprot id: A0A191WDS7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

453304:ATC03 RS08685
gene id: 453304:ATC03_RS08685
uniprot id: A0A191WF19
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS03170
gene id: 453304:ATC03_RS03170
uniprot id: A0A191WCG9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS06995
gene id: 453304:ATC03_RS06995
uniprot id: A0A191WE02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

453304:ATC03 RS05880
gene id: 453304:ATC03_RS05880
uniprot id: A0A191WDG7
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS03790
gene id: 453304:ATC03_RS03790
uniprot id: A0A191WCS7
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS14600
gene id: 453304:ATC03_RS14600
uniprot id: A0A191WL60
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

453304:ATC03 RS13945
gene id: 453304:ATC03_RS13945
uniprot id: A0A191WHI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

453304:ATC03 RS14120
gene id: 453304:ATC03_RS14120
uniprot id: A0A191WHL7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

453304:ATC03 RS10925
gene id: 453304:ATC03_RS10925
uniprot id: A0A191WG49
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

453304:ATC03 RS05370
gene id: 453304:ATC03_RS05370
uniprot id: A0A191WDI0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.
messages: Belongs to the FMO family.

453304:ATC03 RS11290
gene id: 453304:ATC03_RS11290
uniprot id: A0A191WG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

453304:ATC03 RS07855
gene id: 453304:ATC03_RS07855
uniprot id: A0A191WEL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

453304:ATC03 RS11225
gene id: 453304:ATC03_RS11225
uniprot id: A0A191WFY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS14390
gene id: 453304:ATC03_RS14390
uniprot id: A0A191WHE5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS13030
gene id: 453304:ATC03_RS13030
uniprot id: A0A191WGS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

453304:ATC03 RS06615
gene id: 453304:ATC03_RS06615
uniprot id: A0A191WE19
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

453304:ATC03 RS12165
gene id: 453304:ATC03_RS12165
uniprot id: A0A191WGD9
names: Similarity
messages: Belongs to the CsoR family.

453304:ATC03 RS09020
gene id: 453304:ATC03_RS09020
uniprot id: A0A191WF72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

453304:ATC03 RS12190
gene id: 453304:ATC03_RS12190
uniprot id: A0A191WGR0
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS10520
gene id: 453304:ATC03_RS10520
uniprot id: A0A191WFN2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

453304:ATC03 RS03380
gene id: 453304:ATC03_RS03380
uniprot id: A0A191WCG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

453304:ATC03 RS00890
gene id: 453304:ATC03_RS00890
uniprot id: A0A191WBA8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS13890
gene id: 453304:ATC03_RS13890
uniprot id: A0A191WH60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

453304:ATC03 RS01110
gene id: 453304:ATC03_RS01110
uniprot id: A0A191WBK4
names: Similarity
messages: Belongs to the peptidase C56 family.

453304:ATC03 RS10190
gene id: 453304:ATC03_RS10190
uniprot id: A0A191WFS8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

453304:ATC03 RS11555
gene id: 453304:ATC03_RS11555
uniprot id: A0A191WGH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS16650
gene id: 453304:ATC03_RS16650
uniprot id: A0A191WIL2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

453304:ATC03 RS10770
gene id: 453304:ATC03_RS10770
uniprot id: A0A191WKU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

453304:ATC03 RS05040
gene id: 453304:ATC03_RS05040
uniprot id: A0A191WD38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS09675
gene id: 453304:ATC03_RS09675
uniprot id: A0A191WFI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

453304:ATC03 RS02750
gene id: 453304:ATC03_RS02750
uniprot id: A0A191WCC1
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS07290
gene id: 453304:ATC03_RS07290
uniprot id: A0A191WE46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

453304:ATC03 RS04240
gene id: 453304:ATC03_RS04240
uniprot id: A0A191WD06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS14385
gene id: 453304:ATC03_RS14385
uniprot id: A0A191WHR5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

453304:ATC03 RS00855
gene id: 453304:ATC03_RS00855
uniprot id: A0A191WBA2
names: Similarity
messages: Belongs to the citrate synthase family.

453304:ATC03 RS15020
gene id: 453304:ATC03_RS15020
uniprot id: A0A191WI23
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

453304:ATC03 RS04855
gene id: 453304:ATC03_RS04855
uniprot id: A0A191WDA3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

453304:ATC03 RS02220
gene id: 453304:ATC03_RS02220
uniprot id: A0A191WBX2
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS07790
gene id: 453304:ATC03_RS07790
uniprot id: A0A191WEC9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS00565
gene id: 453304:ATC03_RS00565
uniprot id: A0A191WBB0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

453304:ATC03 RS00240
gene id: 453304:ATC03_RS00240
uniprot id: A0A191WB19
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS11510
gene id: 453304:ATC03_RS11510
uniprot id: A0A191WG39
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

453304:ATC03 RS14430
gene id: 453304:ATC03_RS14430
uniprot id: A0A191WHM8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

453304:ATC03 RS11415
gene id: 453304:ATC03_RS11415
uniprot id: A0A191WKX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

453304:ATC03 RS18335
gene id: 453304:ATC03_RS18335
uniprot id: A0A191WJG9
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

453304:ATC03 RS12110
gene id: 453304:ATC03_RS12110
uniprot id: A0A191WGC9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09900
gene id: 453304:ATC03_RS09900
uniprot id: A0A191WFC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

453304:ATC03 RS11705
gene id: 453304:ATC03_RS11705
uniprot id: A0A191WKZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

453304:ATC03 RS14005
gene id: 453304:ATC03_RS14005
uniprot id: A0A191WH81
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS05230
gene id: 453304:ATC03_RS05230
uniprot id: A0A191WD68
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

453304:ATC03 RS00665
gene id: 453304:ATC03_RS00665
uniprot id: A0A191WBD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS01795
gene id: 453304:ATC03_RS01795
uniprot id: A0A191WKC5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

453304:ATC03 RS15285
gene id: 453304:ATC03_RS15285
uniprot id: A0A191WHY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

453304:ATC03 RS11175
gene id: 453304:ATC03_RS11175
uniprot id: A0A191WG97
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS10100
gene id: 453304:ATC03_RS10100
uniprot id: A0A191WFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

453304:ATC03 RS06915
gene id: 453304:ATC03_RS06915
uniprot id: A0A191WE42
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

453304:ATC03 RS10800
gene id: 453304:ATC03_RS10800
uniprot id: A0A191WG32
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS03730
gene id: 453304:ATC03_RS03730
uniprot id: A0A191WCR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS14995
gene id: 453304:ATC03_RS14995
uniprot id: A0A191WI18
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS13650
gene id: 453304:ATC03_RS13650
uniprot id: A0A191WH59
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

453304:ATC03 RS07065
gene id: 453304:ATC03_RS07065
uniprot id: A0A191WE20
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

453304:ATC03 RS15355
gene id: 453304:ATC03_RS15355
uniprot id: A0A191WHV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

453304:ATC03 RS12610
gene id: 453304:ATC03_RS12610
uniprot id: A0A191WGX4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

453304:ATC03 RS05050
gene id: 453304:ATC03_RS05050
uniprot id: A0A191WD85
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

453304:ATC03 RS09230
gene id: 453304:ATC03_RS09230
uniprot id: A0A191WF70
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

453304:ATC03 RS07375
gene id: 453304:ATC03_RS07375
uniprot id: A0A191WE62
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

453304:ATC03 RS07020
gene id: 453304:ATC03_RS07020
uniprot id: A0A191WEB3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

453304:ATC03 RS09745
gene id: 453304:ATC03_RS09745
uniprot id: A0A191WFG0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS05215
gene id: 453304:ATC03_RS05215
uniprot id: A0A191WDD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

453304:ATC03 RS14840
gene id: 453304:ATC03_RS14840
uniprot id: A0A191WHZ4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

453304:ATC03 RS12670
gene id: 453304:ATC03_RS12670
uniprot id: A0A191WGY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

453304:ATC03 RS07370
gene id: 453304:ATC03_RS07370
uniprot id: A0A191WEG8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

453304:ATC03 RS12950
gene id: 453304:ATC03_RS12950
uniprot id: A0A191WGY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS09105
gene id: 453304:ATC03_RS09105
uniprot id: A0A191WF87
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS10250
gene id: 453304:ATC03_RS10250
uniprot id: A0A191WFL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

453304:ATC03 RS18265
gene id: 453304:ATC03_RS18265
uniprot id: A0A191WJB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

453304:ATC03 RS18930
gene id: 453304:ATC03_RS18930
uniprot id: A0A191WJF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

453304:ATC03 RS05485
gene id: 453304:ATC03_RS05485
uniprot id: A0A191WDK6
names: Similarity
messages: Belongs to the DSD1 family.

453304:ATC03 RS14550
gene id: 453304:ATC03_RS14550
uniprot id: A0A191WHH1
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS14380
gene id: 453304:ATC03_RS14380
uniprot id: A0A191WHR4
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

453304:ATC03 RS06945
gene id: 453304:ATC03_RS06945
uniprot id: A0A191WE00
names: Subcellular Location Annotation
messages: Cell membrane

453304:ATC03 RS12525
gene id: 453304:ATC03_RS12525
uniprot id: A0A191WGV7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

453304:ATC03 RS06175
gene id: 453304:ATC03_RS06175
uniprot id: A0A191WDL6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

453304:ATC03 RS14070
gene id: 453304:ATC03_RS14070
uniprot id: A0A191WL45
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS13530
gene id: 453304:ATC03_RS13530
uniprot id: A0A191WHC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

453304:ATC03 RS02590
gene id: 453304:ATC03_RS02590
uniprot id: A0A191WC40
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

453304:ATC03 RS07825
gene id: 453304:ATC03_RS07825
uniprot id: A0A191WEI1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

453304:ATC03 RS09830
gene id: 453304:ATC03_RS09830
uniprot id: A0A191WFL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS15860
gene id: 453304:ATC03_RS15860
uniprot id: A0A191WI30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

453304:ATC03 RS15365
gene id: 453304:ATC03_RS15365
uniprot id: A0A191WHZ9
names: Similarity
messages: Belongs to the IMPACT family.

453304:ATC03 RS03220
gene id: 453304:ATC03_RS03220
uniprot id: A0A191WCD2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

453304:ATC03 RS09595
gene id: 453304:ATC03_RS09595
uniprot id: A0A191WFH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

453304:ATC03 RS01935
gene id: 453304:ATC03_RS01935
uniprot id: A0A191WBZ0
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

453304:ATC03 RS08055
gene id: 453304:ATC03_RS08055
uniprot id: A0A191WEQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS18885
gene id: 453304:ATC03_RS18885
uniprot id: A0A191WJQ4
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS12435
gene id: 453304:ATC03_RS12435
uniprot id: A0A191WGP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS10300
gene id: 453304:ATC03_RS10300
uniprot id: A0A191WFJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS08260
gene id: 453304:ATC03_RS08260
uniprot id: A0A191WEU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

453304:ATC03 RS12620
gene id: 453304:ATC03_RS12620
uniprot id: A0A191WGW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

453304:ATC03 RS13885
gene id: 453304:ATC03_RS13885
uniprot id: A0A191WHH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

453304:ATC03 RS17620
gene id: 453304:ATC03_RS17620
uniprot id: A0A191WJ60
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

453304:ATC03 RS10440
gene id: 453304:ATC03_RS10440
uniprot id: A0A191WFX3
names: Similarity
messages: Belongs to the glutamine synthetase family.

453304:ATC03 RS17930
gene id: 453304:ATC03_RS17930
uniprot id: A0A191WJ07
names: Subunit
messages: Homodimer.

453304:ATC03 RS08570
gene id: 453304:ATC03_RS08570
uniprot id: A0A191WEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

453304:ATC03 RS19345
gene id: 453304:ATC03_RS19345
uniprot id: A0A191WJM4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

453304:ATC03 RS03310
gene id: 453304:ATC03_RS03310
uniprot id: A0A191WCF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

453304:ATC03 RS00720
gene id: 453304:ATC03_RS00720
uniprot id: A0A191WBE6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

453304:ATC03 RS08440
gene id: 453304:ATC03_RS08440
uniprot id: A0A191WKS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

453304:ATC03 RS17755
gene id: 453304:ATC03_RS17755
uniprot id: A0A191WIX8
names: Similarity
messages: Belongs to the GARS family.

453304:ATC03 RS06930
gene id: 453304:ATC03_RS06930
uniprot id: A0A191WE98
names: Similarity
messages: Belongs to the peptidase S8 family.

453304:ATC03 RS07775
gene id: 453304:ATC03_RS07775
uniprot id: A0A191WKP9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

453304:ATC03 RS00930
gene id: 453304:ATC03_RS00930
uniprot id: A0A191WBC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

453304:ATC03 RS06935
gene id: 453304:ATC03_RS06935
uniprot id: A0A191WDZ3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

453304:ATC03 RS04615
gene id: 453304:ATC03_RS04615
uniprot id: A0A191WD66
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

453304:ATC03 RS15555
gene id: 453304:ATC03_RS15555
uniprot id: A0A191WIC3
names: Similarity
messages: Belongs to the ComB family.

453304:ATC03 RS02870
gene id: 453304:ATC03_RS02870
uniprot id: A0A191WC58
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS18255
gene id: 453304:ATC03_RS18255
uniprot id: A0A191WJK1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS15310
gene id: 453304:ATC03_RS15310
uniprot id: A0A191WHY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

453304:ATC03 RS05300
gene id: 453304:ATC03_RS05300
uniprot id: A0A191WD78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

453304:ATC03 RS14955
gene id: 453304:ATC03_RS14955
uniprot id: A0A191WHN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

453304:ATC03 RS19630
gene id: 453304:ATC03_RS19630
uniprot id: A0A191WLI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

453304:ATC03 RS09705
gene id: 453304:ATC03_RS09705
uniprot id: A0A191WFJ6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

453304:ATC03 RS15140
gene id: 453304:ATC03_RS15140
uniprot id: A0A191WHR6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

453304:ATC03 RS01050
gene id: 453304:ATC03_RS01050
uniprot id: A0A191WBK6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS16395
gene id: 453304:ATC03_RS16395
uniprot id: A0A191WIQ5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS08530
gene id: 453304:ATC03_RS08530
uniprot id: A0A191WER6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

453304:ATC03 RS14460
gene id: 453304:ATC03_RS14460
uniprot id: A0A191WHT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS14055
gene id: 453304:ATC03_RS14055
uniprot id: A0A191WHK7
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

453304:ATC03 RS15205
gene id: 453304:ATC03_RS15205
uniprot id: A0A191WHW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

453304:ATC03 RS21190
gene id: 453304:ATC03_RS21190
uniprot id: A0A191WD32
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

453304:ATC03 RS14750
gene id: 453304:ATC03_RS14750
uniprot id: A0A191WHX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS17565
gene id: 453304:ATC03_RS17565
uniprot id: A0A191WJ08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

453304:ATC03 RS06910
gene id: 453304:ATC03_RS06910
uniprot id: A0A191WKS8
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

453304:ATC03 RS00545
gene id: 453304:ATC03_RS00545
uniprot id: A0A191WB48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

453304:ATC03 RS02770
gene id: 453304:ATC03_RS02770
uniprot id: A0A191WKE3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

453304:ATC03 RS16030
gene id: 453304:ATC03_RS16030
uniprot id: A0A191WII7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS17555
gene id: 453304:ATC03_RS17555
uniprot id: A0A191WJ89
names: Similarity
messages: Belongs to the arginase family.

453304:ATC03 RS03935
gene id: 453304:ATC03_RS03935
uniprot id: A0A191WCL8
names: Similarity
messages: Belongs to the peptidase M1 family.

453304:ATC03 RS16155
gene id: 453304:ATC03_RS16155
uniprot id: A0A191WIL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS18170
gene id: 453304:ATC03_RS18170
uniprot id: A0A191WJ39
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS05675
gene id: 453304:ATC03_RS05675
uniprot id: A0A191WDK4
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

453304:ATC03 RS13305
gene id: 453304:ATC03_RS13305
uniprot id: A0A191WH43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

453304:ATC03 RS17995
gene id: 453304:ATC03_RS17995
uniprot id: A0A191WJH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS05835
gene id: 453304:ATC03_RS05835
uniprot id: A0A191WDG3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

453304:ATC03 RS09540
gene id: 453304:ATC03_RS09540
uniprot id: A0A191WFG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

453304:ATC03 RS05430
gene id: 453304:ATC03_RS05430
uniprot id: A0A191WD99
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS12520
gene id: 453304:ATC03_RS12520
uniprot id: A0A191WGQ4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

453304:ATC03 RS07440
gene id: 453304:ATC03_RS07440
uniprot id: A0A191WEH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

453304:ATC03 RS13995
gene id: 453304:ATC03_RS13995
uniprot id: A0A191WHK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

453304:ATC03 RS11380
gene id: 453304:ATC03_RS11380
uniprot id: A0A191WGC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

453304:ATC03 RS19045
gene id: 453304:ATC03_RS19045
uniprot id: A0A191WJW7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

453304:ATC03 RS05755
gene id: 453304:ATC03_RS05755
uniprot id: A0A191WDM0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

453304:ATC03 RS15685
gene id: 453304:ATC03_RS15685
uniprot id: A0A191WID4
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

453304:ATC03 RS11065
gene id: 453304:ATC03_RS11065
uniprot id: A0A191WG83
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS13805
gene id: 453304:ATC03_RS13805
uniprot id: A0A191WH84
names: Similarity
messages: Belongs to the UPF0045 family.

453304:ATC03 RS19900
gene id: 453304:ATC03_RS19900
uniprot id: A0A191WJS8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS18480
gene id: 453304:ATC03_RS18480
uniprot id: A0A191WJJ4
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

453304:ATC03 RS12480
gene id: 453304:ATC03_RS12480
uniprot id: A0A191WGP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

453304:ATC03 RS09850
gene id: 453304:ATC03_RS09850
uniprot id: A0A191WFH9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

453304:ATC03 RS13080
gene id: 453304:ATC03_RS13080
uniprot id: A0A191WH45
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

453304:ATC03 RS18960
gene id: 453304:ATC03_RS18960
uniprot id: A0A191WJF7
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

453304:ATC03 RS07850
gene id: 453304:ATC03_RS07850
uniprot id: A0A191WEI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

453304:ATC03 RS13545
gene id: 453304:ATC03_RS13545
uniprot id: A0A191WH44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

453304:ATC03 RS17455
gene id: 453304:ATC03_RS17455
uniprot id: A0A191WJ32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

453304:ATC03 RS06675
gene id: 453304:ATC03_RS06675
uniprot id: A0A191WE01
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

453304:ATC03 RS06575
gene id: 453304:ATC03_RS06575
uniprot id: A0A191WDU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

453304:ATC03 RS05405
gene id: 453304:ATC03_RS05405
uniprot id: A0A191WD94
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

453304:ATC03 RS03470
gene id: 453304:ATC03_RS03470
uniprot id: A0A191WCH5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

453304:ATC03 RS07540
gene id: 453304:ATC03_RS07540
uniprot id: A0A191WED6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

453304:ATC03 RS09855
gene id: 453304:ATC03_RS09855
uniprot id: A0A191WFM2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

453304:ATC03 RS03575
gene id: 453304:ATC03_RS03575
uniprot id: A0A191WCG2
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS02805
gene id: 453304:ATC03_RS02805
uniprot id: A0A191WC70
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

453304:ATC03 RS12690
gene id: 453304:ATC03_RS12690
uniprot id: A0A191WGQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

453304:ATC03 RS18190
gene id: 453304:ATC03_RS18190
uniprot id: A0A191WJJ1
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS01225
gene id: 453304:ATC03_RS01225
uniprot id: A0A191WBN3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

453304:ATC03 RS06370
gene id: 453304:ATC03_RS06370
uniprot id: A0A191WE03
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

453304:ATC03 RS18865
gene id: 453304:ATC03_RS18865
uniprot id: A0A191WJU1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

453304:ATC03 RS04780
gene id: 453304:ATC03_RS04780
uniprot id: A0A191WD00
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

453304:ATC03 RS06450
gene id: 453304:ATC03_RS06450
uniprot id: A0A191WDY6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

453304:ATC03 RS06815
gene id: 453304:ATC03_RS06815
uniprot id: A0A191WE26
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS10820
gene id: 453304:ATC03_RS10820
uniprot id: A0A191WFZ0
names: Similarity
messages: Belongs to the cytochrome P450 family.

453304:ATC03 RS13855
gene id: 453304:ATC03_RS13855
uniprot id: A0A191WHH0
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS15245
gene id: 453304:ATC03_RS15245
uniprot id: A0A191WI64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

453304:ATC03 RS12030
gene id: 453304:ATC03_RS12030
uniprot id: A0A191WGB4
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

453304:ATC03 RS09350
gene id: 453304:ATC03_RS09350
uniprot id: A0A191WFD3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

453304:ATC03 RS03655
gene id: 453304:ATC03_RS03655
uniprot id: A0A191WCH3
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS13175
gene id: 453304:ATC03_RS13175
uniprot id: A0A191WH61
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

453304:ATC03 RS15955
gene id: 453304:ATC03_RS15955
uniprot id: A0A191WII1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: In the N-terminal section; belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

453304:ATC03 RS09760
gene id: 453304:ATC03_RS09760
uniprot id: A0A191WFA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

453304:ATC03 RS19395
gene id: 453304:ATC03_RS19395
uniprot id: A0A191WK35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS00305
gene id: 453304:ATC03_RS00305
uniprot id: A0A191WB29
names: Similarity
messages: Belongs to the group II decarboxylase family.

453304:ATC03 RS09875
gene id: 453304:ATC03_RS09875
uniprot id: A0A191WFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

453304:ATC03 RS09835
gene id: 453304:ATC03_RS09835
uniprot id: A0A191WFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS02340
gene id: 453304:ATC03_RS02340
uniprot id: A0A191WBY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

453304:ATC03 RS09680
gene id: 453304:ATC03_RS09680
uniprot id: A0A191WFJ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

453304:ATC03 RS19155
gene id: 453304:ATC03_RS19155
uniprot id: A0A191WJJ0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

453304:ATC03 RS16680
gene id: 453304:ATC03_RS16680
uniprot id: A0A191WIQ8
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

453304:ATC03 RS13675
gene id: 453304:ATC03_RS13675
uniprot id: A0A191WHE2
names: Similarity
messages: Belongs to the PspA/IM30 family.

453304:ATC03 RS08535
gene id: 453304:ATC03_RS08535
uniprot id: A0A191WEV3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS10835
gene id: 453304:ATC03_RS10835
uniprot id: A0A191WG36
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

453304:ATC03 RS15250
gene id: 453304:ATC03_RS15250
uniprot id: A0A191WI60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

453304:ATC03 RS00015
gene id: 453304:ATC03_RS00015
uniprot id: A0A191WAY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

453304:ATC03 RS05390
gene id: 453304:ATC03_RS05390
uniprot id: A0A191WDF6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS12360
gene id: 453304:ATC03_RS12360
uniprot id: A0A191WGK1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

453304:ATC03 RS02715
gene id: 453304:ATC03_RS02715
uniprot id: A0A191WCB6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS17955
gene id: 453304:ATC03_RS17955
uniprot id: A0A191WJ12
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

453304:ATC03 RS01990
gene id: 453304:ATC03_RS01990
uniprot id: A0A191WBT0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

453304:ATC03 RS19085
gene id: 453304:ATC03_RS19085
uniprot id: A0A191WJT5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS11595
gene id: 453304:ATC03_RS11595
uniprot id: A0A191WGB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

453304:ATC03 RS08375
gene id: 453304:ATC03_RS08375
uniprot id: A0A191WEW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

453304:ATC03 RS13540
gene id: 453304:ATC03_RS13540
uniprot id: A0A191WH06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

453304:ATC03 RS16200
gene id: 453304:ATC03_RS16200
uniprot id: A0A191WIH8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS07830
gene id: 453304:ATC03_RS07830
uniprot id: A0A191WEL3
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

453304:ATC03 RS16050
gene id: 453304:ATC03_RS16050
uniprot id: A0A191WIJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase.

453304:ATC03 RS00030
gene id: 453304:ATC03_RS00030
uniprot id: A0A191WJT7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

453304:ATC03 RS11660
gene id: 453304:ATC03_RS11660
uniprot id: A0A191WG58
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

453304:ATC03 RS05425
gene id: 453304:ATC03_RS05425
uniprot id: A0A191WDJ0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

453304:ATC03 RS09615
gene id: 453304:ATC03_RS09615
uniprot id: A0A191WFH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

453304:ATC03 RS12180
gene id: 453304:ATC03_RS12180
uniprot id: A0A191WL13
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS10665
gene id: 453304:ATC03_RS10665
uniprot id: A0A191WFQ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

453304:ATC03 RS04470
gene id: 453304:ATC03_RS04470
uniprot id: A0A191WD17
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

453304:ATC03 RS10420
gene id: 453304:ATC03_RS10420
uniprot id: A0A191WFX1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

453304:ATC03 RS03365
gene id: 453304:ATC03_RS03365
uniprot id: A0A191WCD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS16935
gene id: 453304:ATC03_RS16935
uniprot id: A0A191WIV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS05695
gene id: 453304:ATC03_RS05695
uniprot id: A0A191WDI8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS17475
gene id: 453304:ATC03_RS17475
uniprot id: A0A191WIT2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

453304:ATC03 RS11465
gene id: 453304:ATC03_RS11465
uniprot id: A0A191WG94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS13770
gene id: 453304:ATC03_RS13770
uniprot id: A0A191WHF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

453304:ATC03 RS15120
gene id: 453304:ATC03_RS15120
uniprot id: A0A191WHV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

453304:ATC03 RS09585
gene id: 453304:ATC03_RS09585
uniprot id: A0A191WFD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

453304:ATC03 RS07270
gene id: 453304:ATC03_RS07270
uniprot id: A0A191WKN7
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS12380
gene id: 453304:ATC03_RS12380
uniprot id: A0A191WGS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

453304:ATC03 RS14355
gene id: 453304:ATC03_RS14355
uniprot id: A0A191WHQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

453304:ATC03 RS10450
gene id: 453304:ATC03_RS10450
uniprot id: A0A191WFM1
names: Similarity
messages: Belongs to the glutamine synthetase family.

453304:ATC03 RS05970
gene id: 453304:ATC03_RS05970
uniprot id: A0A191WDT3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

453304:ATC03 RS12600
gene id: 453304:ATC03_RS12600
uniprot id: A0A191WGN8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

453304:ATC03 RS02790
gene id: 453304:ATC03_RS02790
uniprot id: A0A191WCC6
names: Similarity
messages: Belongs to the YciI family.

453304:ATC03 RS13605
gene id: 453304:ATC03_RS13605
uniprot id: A0A191WHD8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

453304:ATC03 RS09905
gene id: 453304:ATC03_RS09905
uniprot id: A0A191WFF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS19335
gene id: 453304:ATC03_RS19335
uniprot id: A0A191WK40
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

453304:ATC03 RS17115
gene id: 453304:ATC03_RS17115
uniprot id: A0A191WIT1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

453304:ATC03 RS09780
gene id: 453304:ATC03_RS09780
uniprot id: A0A191WFL0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

453304:ATC03 RS04845
gene id: 453304:ATC03_RS04845
uniprot id: A0A191WD54
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

453304:ATC03 RS11395
gene id: 453304:ATC03_RS11395
uniprot id: A0A191WG54
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

453304:ATC03 RS16815
gene id: 453304:ATC03_RS16815
uniprot id: A0A191WII4
names: Similarity
messages: Belongs to the peptidase S8 family.

453304:ATC03 RS08645
gene id: 453304:ATC03_RS08645
uniprot id: A0A191WF02
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

453304:ATC03 RS11570
gene id: 453304:ATC03_RS11570
uniprot id: A0A191WKZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS09180
gene id: 453304:ATC03_RS09180
uniprot id: A0A191WF97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

453304:ATC03 RS07000
gene id: 453304:ATC03_RS07000
uniprot id: A0A191WE10
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS04950
gene id: 453304:ATC03_RS04950
uniprot id: A0A191WKI7
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS06485
gene id: 453304:ATC03_RS06485
uniprot id: A0A191WE23
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS01060
gene id: 453304:ATC03_RS01060
uniprot id: A0A191WBD8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

453304:ATC03 RS18050
gene id: 453304:ATC03_RS18050
uniprot id: A0A191WJC9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS10900
gene id: 453304:ATC03_RS10900
uniprot id: A0A191WFX2
names: Cofactor
messages: Binds 2 manganese ions per subunit.

453304:ATC03 RS09260
gene id: 453304:ATC03_RS09260
uniprot id: A0A191WF75
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

453304:ATC03 RS05100
gene id: 453304:ATC03_RS05100
uniprot id: A0A191WD60
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS06760
gene id: 453304:ATC03_RS06760
uniprot id: A0A191WE16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

453304:ATC03 RS15435
gene id: 453304:ATC03_RS15435
uniprot id: A0A191WHW7
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS14375
gene id: 453304:ATC03_RS14375
uniprot id: A0A191WHL6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

453304:ATC03 RS05760
gene id: 453304:ATC03_RS05760
uniprot id: A0A191WDP9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

453304:ATC03 RS07095
gene id: 453304:ATC03_RS07095
uniprot id: A0A191WE17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

453304:ATC03 RS14780
gene id: 453304:ATC03_RS14780
uniprot id: A0A191WHY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

453304:ATC03 RS07170
gene id: 453304:ATC03_RS07170
uniprot id: A0A191WE81
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS15015
gene id: 453304:ATC03_RS15015
uniprot id: A0A191WI21
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

453304:ATC03 RS07235
gene id: 453304:ATC03_RS07235
uniprot id: A0A191WEC2
names: Similarity
messages: Belongs to the FPG family.

453304:ATC03 RS17570
gene id: 453304:ATC03_RS17570
uniprot id: A0A191WJ51
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

453304:ATC03 RS19185
gene id: 453304:ATC03_RS19185
uniprot id: A0A191WJR6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS00460
gene id: 453304:ATC03_RS00460
uniprot id: A0A191WB33
names: Similarity
messages: Belongs to the EfeM/EfeO family.

453304:ATC03 RS08400
gene id: 453304:ATC03_RS08400
uniprot id: A0A191WEX1
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

453304:ATC03 RS08495
gene id: 453304:ATC03_RS08495
uniprot id: A0A191WER0
names: Similarity
messages: Belongs to the UPF0102 family.

453304:ATC03 RS11350
gene id: 453304:ATC03_RS11350
uniprot id: A0A191WGC8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

453304:ATC03 RS15195
gene id: 453304:ATC03_RS15195
uniprot id: A0A191WI49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

453304:ATC03 RS19455
gene id: 453304:ATC03_RS19455
uniprot id: A0A191WK45
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

453304:ATC03 RS09165
gene id: 453304:ATC03_RS09165
uniprot id: A0A191WF60
names: Similarity
messages: Belongs to the Dps family.

453304:ATC03 RS11180
gene id: 453304:ATC03_RS11180
uniprot id: A0A191WG84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

453304:ATC03 RS07890
gene id: 453304:ATC03_RS07890
uniprot id: A0A191WEM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

453304:ATC03 RS12740
gene id: 453304:ATC03_RS12740
uniprot id: A0A191WGY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

453304:ATC03 RS05170
gene id: 453304:ATC03_RS05170
uniprot id: A0A191WD71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS08510
gene id: 453304:ATC03_RS08510
uniprot id: A0A191WEY1
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

453304:ATC03 RS01545
gene id: 453304:ATC03_RS01545
uniprot id: A0A191WBS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

453304:ATC03 RS06790
gene id: 453304:ATC03_RS06790
uniprot id: A0A191WE21
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS19460
gene id: 453304:ATC03_RS19460
uniprot id: A0A191WJP6
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

453304:ATC03 RS10915
gene id: 453304:ATC03_RS10915
uniprot id: A0A191WKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

453304:ATC03 RS07420
gene id: 453304:ATC03_RS07420
uniprot id: A0A191WE66
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

453304:ATC03 RS19610
gene id: 453304:ATC03_RS19610
uniprot id: A0A191WLI4
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09295
gene id: 453304:ATC03_RS09295
uniprot id: A0A191WFC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS13335
gene id: 453304:ATC03_RS13335
uniprot id: A0A191WH10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

453304:ATC03 RS15640
gene id: 453304:ATC03_RS15640
uniprot id: A0A191WI46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

453304:ATC03 RS03775
gene id: 453304:ATC03_RS03775
uniprot id: A0A191WCM1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

453304:ATC03 RS00710
gene id: 453304:ATC03_RS00710
uniprot id: A0A191WBD4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

453304:ATC03 RS10085
gene id: 453304:ATC03_RS10085
uniprot id: A0A191WFL9
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS17680
gene id: 453304:ATC03_RS17680
uniprot id: A0A191WJ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

453304:ATC03 RS10805
gene id: 453304:ATC03_RS10805
uniprot id: A0A191WFS5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS09090
gene id: 453304:ATC03_RS09090
uniprot id: A0A191WF13
names: Similarity
messages: Belongs to the peptidase M1 family.

453304:ATC03 RS13155
gene id: 453304:ATC03_RS13155
uniprot id: A0A191WKV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

453304:ATC03 RS13375
gene id: 453304:ATC03_RS13375
uniprot id: A0A191WH53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

453304:ATC03 RS18830
gene id: 453304:ATC03_RS18830
uniprot id: A0A191WJT8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

453304:ATC03 RS10295
gene id: 453304:ATC03_RS10295
uniprot id: A0A191WFU7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS02785
gene id: 453304:ATC03_RS02785
uniprot id: A0A191WCB3
names: Similarity
messages: Belongs to the YciI family.

453304:ATC03 RS06715
gene id: 453304:ATC03_RS06715
uniprot id: A0A191WDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

453304:ATC03 RS05915
gene id: 453304:ATC03_RS05915
uniprot id: A0A191WDH2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

453304:ATC03 RS07530
gene id: 453304:ATC03_RS07530
uniprot id: A0A191WE82
names: Similarity
messages: Belongs to the peptidase S16 family.

453304:ATC03 RS03675
gene id: 453304:ATC03_RS03675
uniprot id: A0A191WCK6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS07085
gene id: 453304:ATC03_RS07085
uniprot id: A0A191WE94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

453304:ATC03 RS13485
gene id: 453304:ATC03_RS13485
uniprot id: A0A191WH34
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

453304:ATC03 RS10235
gene id: 453304:ATC03_RS10235
uniprot id: A0A191WKV8
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS15320
gene id: 453304:ATC03_RS15320
uniprot id: A0A191WI84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

453304:ATC03 RS09530
gene id: 453304:ATC03_RS09530
uniprot id: A0A191WFF9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

453304:ATC03 RS02855
gene id: 453304:ATC03_RS02855
uniprot id: A0A191WCC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

453304:ATC03 RS17595
gene id: 453304:ATC03_RS17595
uniprot id: A0A191WJ94
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS11845
gene id: 453304:ATC03_RS11845
uniprot id: A0A191WGC5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

453304:ATC03 RS06340
gene id: 453304:ATC03_RS06340
uniprot id: A0A191WDZ8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

453304:ATC03 RS05950
gene id: 453304:ATC03_RS05950
uniprot id: A0A191WDH7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS17450
gene id: 453304:ATC03_RS17450
uniprot id: A0A191WIY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

453304:ATC03 RS11005
gene id: 453304:ATC03_RS11005
uniprot id: A0A191WKV6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS14585
gene id: 453304:ATC03_RS14585
uniprot id: A0A191WHH9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

453304:ATC03 RS13550
gene id: 453304:ATC03_RS13550
uniprot id: A0A191WH83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

453304:ATC03 RS13735
gene id: 453304:ATC03_RS13735
uniprot id: A0A191WHA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

453304:ATC03 RS13380
gene id: 453304:ATC03_RS13380
uniprot id: A0A191WHA3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS10590
gene id: 453304:ATC03_RS10590
uniprot id: A0A191WFV5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

453304:ATC03 RS07430
gene id: 453304:ATC03_RS07430
uniprot id: A0A191WEC0
names: Similarity
messages: Belongs to the group II decarboxylase family.

453304:ATC03 RS10550
gene id: 453304:ATC03_RS10550
uniprot id: A0A191WFN6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS18450
gene id: 453304:ATC03_RS18450
uniprot id: A0A191WJI9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

453304:ATC03 RS09985
gene id: 453304:ATC03_RS09985
uniprot id: A0A191WFE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

453304:ATC03 RS09535
gene id: 453304:ATC03_RS09535
uniprot id: A0A191WKS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

453304:ATC03 RS15505
gene id: 453304:ATC03_RS15505
uniprot id: A0A191WHX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

453304:ATC03 RS11530
gene id: 453304:ATC03_RS11530
uniprot id: A0A191WGG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

453304:ATC03 RS17510
gene id: 453304:ATC03_RS17510
uniprot id: A0A191WIZ7
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS02085
gene id: 453304:ATC03_RS02085
uniprot id: A0A191WBW5
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS01745
gene id: 453304:ATC03_RS01745
uniprot id: A0A191WBV0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

453304:ATC03 RS10555
gene id: 453304:ATC03_RS10555
uniprot id: A0A191WKW3
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

453304:ATC03 RS11025
gene id: 453304:ATC03_RS11025
uniprot id: A0A191WFZ2
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

453304:ATC03 RS01840
gene id: 453304:ATC03_RS01840
uniprot id: A0A191WBS3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

453304:ATC03 RS13630
gene id: 453304:ATC03_RS13630
uniprot id: A0A191WH92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

453304:ATC03 RS16005
gene id: 453304:ATC03_RS16005
uniprot id: A0A191WIA0
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS02595
gene id: 453304:ATC03_RS02595
uniprot id: A0A191WC88
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

453304:ATC03 RS00335
gene id: 453304:ATC03_RS00335
uniprot id: A0A191WB13
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS18580
gene id: 453304:ATC03_RS18580
uniprot id: A0A191WJR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

453304:ATC03 RS02575
gene id: 453304:ATC03_RS02575
uniprot id: A0A191WC20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

453304:ATC03 RS15500
gene id: 453304:ATC03_RS15500
uniprot id: A0A191WIA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

453304:ATC03 RS16015
gene id: 453304:ATC03_RS16015
uniprot id: A0A191WIE3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

453304:ATC03 RS15045
gene id: 453304:ATC03_RS15045
uniprot id: A0A191WI29
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

453304:ATC03 RS08275
gene id: 453304:ATC03_RS08275
uniprot id: A0A191WEQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

453304:ATC03 RS13270
gene id: 453304:ATC03_RS13270
uniprot id: A0A191WGW2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

453304:ATC03 RS10330
gene id: 453304:ATC03_RS10330
uniprot id: A0A191WFM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

453304:ATC03 RS15290
gene id: 453304:ATC03_RS15290
uniprot id: A0A191WI27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

453304:ATC03 RS15255
gene id: 453304:ATC03_RS15255
uniprot id: A0A191WHT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

453304:ATC03 RS02650
gene id: 453304:ATC03_RS02650
uniprot id: A0A191WK08
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

453304:ATC03 RS12455
gene id: 453304:ATC03_RS12455
uniprot id: A0A191WGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

453304:ATC03 RS03910
gene id: 453304:ATC03_RS03910
uniprot id: A0A191WCL3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

453304:ATC03 RS01565
gene id: 453304:ATC03_RS01565
uniprot id: A0A191WBR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

453304:ATC03 RS18690
gene id: 453304:ATC03_RS18690
uniprot id: A0A191WJB8
names: Similarity
messages: Belongs to the AHA1 family.

453304:ATC03 RS14010
gene id: 453304:ATC03_RS14010
uniprot id: A0A191WHB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

453304:ATC03 RS16660
gene id: 453304:ATC03_RS16660
uniprot id: A0A191WIU8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

453304:ATC03 RS05655
gene id: 453304:ATC03_RS05655
uniprot id: A0A191WDD7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

453304:ATC03 RS12695
gene id: 453304:ATC03_RS12695
uniprot id: A0A191WGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

453304:ATC03 RS08050
gene id: 453304:ATC03_RS08050
uniprot id: A0A191WEP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

453304:ATC03 RS11490
gene id: 453304:ATC03_RS11490
uniprot id: A0A191WGA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

453304:ATC03 RS20855
gene id: 453304:ATC03_RS20855
uniprot id: A0A191WIC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

453304:ATC03 RS09480
gene id: 453304:ATC03_RS09480
uniprot id: A0A191WFF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

453304:ATC03 RS16095
gene id: 453304:ATC03_RS16095
uniprot id: A0A191WIB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS18710
gene id: 453304:ATC03_RS18710
uniprot id: A0A191WJT6
names: Subcellular Location Annotation
messages: Membrane

453304:ATC03 RS11755
gene id: 453304:ATC03_RS11755
uniprot id: A0A191WGE0
names: Similarity
messages: Belongs to the UPF0225 family.

453304:ATC03 RS15650
gene id: 453304:ATC03_RS15650
uniprot id: A0A191WID8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

453304:ATC03 RS15200
gene id: 453304:ATC03_RS15200
uniprot id: A0A191WHS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

453304:ATC03 RS01780
gene id: 453304:ATC03_RS01780
uniprot id: A0A191WBW6
names: Similarity
messages: Belongs to the isochorismate synthase family.

453304:ATC03 RS18180
gene id: 453304:ATC03_RS18180
uniprot id: A0A191WJE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

453304:ATC03 RS11220
gene id: 453304:ATC03_RS11220
uniprot id: A0A191WG89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

453304:ATC03 RS18235
gene id: 453304:ATC03_RS18235
uniprot id: A0A191WJ49
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

453304:ATC03 RS05150
gene id: 453304:ATC03_RS05150
uniprot id: A0A191WDC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

453304:ATC03 RS19080
gene id: 453304:ATC03_RS19080
uniprot id: A0A191WJP7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

453304:ATC03 RS09930
gene id: 453304:ATC03_RS09930
uniprot id: A0A191WFG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

453304:ATC03 RS05810
gene id: 453304:ATC03_RS05810
uniprot id: A0A191WDG6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

453304:ATC03 RS14720
gene id: 453304:ATC03_RS14720
uniprot id: A0A191WHX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

453304:ATC03 RS14410
gene id: 453304:ATC03_RS14410
uniprot id: A0A191WHS1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

453304:ATC03 RS11650
gene id: 453304:ATC03_RS11650
uniprot id: A0A191WGI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

453304:ATC03 RS03845
gene id: 453304:ATC03_RS03845
uniprot id: A0A191WCS4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

453304:ATC03 RS18260
gene id: 453304:ATC03_RS18260
uniprot id: A0A191WJ53
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.