45243:CKV80 RS04220
gene id: 45243:CKV80_RS04220
uniprot id: A0A0X8J9J7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

45243:CKV80 RS03165
gene id: 45243:CKV80_RS03165
uniprot id: A0A125S384
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

45243:CKV80 RS03555
gene id: 45243:CKV80_RS03555
uniprot id: A0A0X8J9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

45243:CKV80 RS01945
gene id: 45243:CKV80_RS01945
uniprot id: A0A0X8JAV9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

45243:CKV80 RS10815
gene id: 45243:CKV80_RS10815
uniprot id: A0A125S3Y2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

45243:CKV80 RS11445
gene id: 45243:CKV80_RS11445
uniprot id: A0A0X8JB07
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

45243:CKV80 RS03160
gene id: 45243:CKV80_RS03160
uniprot id: A0A125S385
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

45243:CKV80 RS06885
gene id: 45243:CKV80_RS06885
uniprot id: A0A109W1U3
names: Similarity
messages: Belongs to the Skp family.

45243:CKV80 RS08175
gene id: 45243:CKV80_RS08175
uniprot id: A0A0X8JCY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class A bacterial acid phosphatase family.
messages: Periplasm

45243:CKV80 RS01340
gene id: 45243:CKV80_RS01340
uniprot id: A0A125S3I9
names: Similarity
messages: Belongs to the ParB family.

45243:CKV80 RS07490
gene id: 45243:CKV80_RS07490
uniprot id: A0A125S1Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

45243:CKV80 RS01415
gene id: 45243:CKV80_RS01415
uniprot id: A0A125S3I4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

45243:CKV80 RS09475
gene id: 45243:CKV80_RS09475
uniprot id: A0A0X8JCL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS05790
gene id: 45243:CKV80_RS05790
uniprot id: A0A125S2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS02025
gene id: 45243:CKV80_RS02025
uniprot id: A0A0X8JD38
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

45243:CKV80 RS05500
gene id: 45243:CKV80_RS05500
uniprot id: A0A0X8J9A4
names: Similarity
messages: Belongs to the YoeB family.

45243:CKV80 RS00400
gene id: 45243:CKV80_RS00400
uniprot id: A0A0X8JAT1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

45243:CKV80 RS06695
gene id: 45243:CKV80_RS06695
uniprot id: A0A125S2C5
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS07385
gene id: 45243:CKV80_RS07385
uniprot id: A0A125S205
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

45243:CKV80 RS08430
gene id: 45243:CKV80_RS08430
uniprot id: A0A125S1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

45243:CKV80 RS08800
gene id: 45243:CKV80_RS08800
uniprot id: A0A120KKS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

45243:CKV80 RS01740
gene id: 45243:CKV80_RS01740
uniprot id: A0A0X8JAA2
names: Similarity
messages: Belongs to the SUI1 family.

45243:CKV80 RS11525
gene id: 45243:CKV80_RS11525
uniprot id: A0A0X8JAZ9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

45243:CKV80 RS03990
gene id: 45243:CKV80_RS03990
uniprot id: A0A125S334
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

45243:CKV80 RS01175
gene id: 45243:CKV80_RS01175
uniprot id: A0A125S3J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS00720
gene id: 45243:CKV80_RS00720
uniprot id: A0A0X8JAM9
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

45243:CKV80 RS06110
gene id: 45243:CKV80_RS06110
uniprot id: A0A125S2M1
names: Similarity
messages: Belongs to the peptidase M24B family.

45243:CKV80 RS10025
gene id: 45243:CKV80_RS10025
uniprot id: A0A0X8JC56
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

45243:CKV80 RS02905
gene id: 45243:CKV80_RS02905
uniprot id: A0A125S398
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

45243:CKV80 RS11440
gene id: 45243:CKV80_RS11440
uniprot id: A0A0X8JB31
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

45243:CKV80 RS04490
gene id: 45243:CKV80_RS04490
uniprot id: A0A0X8J9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS04320
gene id: 45243:CKV80_RS04320
uniprot id: A0A0X8J9J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

45243:CKV80 RS02980
gene id: 45243:CKV80_RS02980
uniprot id: A0A125S393
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

45243:CKV80 RS05835
gene id: 45243:CKV80_RS05835
uniprot id: A0A125S2S2
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS09015
gene id: 45243:CKV80_RS09015
uniprot id: A0A0X8JBW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

45243:CKV80 RS04455
gene id: 45243:CKV80_RS04455
uniprot id: A0A0X8J9G3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

45243:CKV80 RS05420
gene id: 45243:CKV80_RS05420
uniprot id: A0A0X8J9C8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

45243:CKV80 RS00975
gene id: 45243:CKV80_RS00975
uniprot id: A0A0X8JCB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

45243:CKV80 RS10645
gene id: 45243:CKV80_RS10645
uniprot id: A0A0X8JBY3
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS03470
gene id: 45243:CKV80_RS03470
uniprot id: A0A0X8JAF1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS04370
gene id: 45243:CKV80_RS04370
uniprot id: A0A0X8JA37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

45243:CKV80 RS00370
gene id: 45243:CKV80_RS00370
uniprot id: A0A0X8JBM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

45243:CKV80 RS11725
gene id: 45243:CKV80_RS11725
uniprot id: A0A125S3S8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

45243:CKV80 RS06430
gene id: 45243:CKV80_RS06430
uniprot id: A0A125S2H2
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

45243:CKV80 RS09895
gene id: 45243:CKV80_RS09895
uniprot id: A0A0X8JC63
names: Similarity
messages: Belongs to the citrate synthase family.

45243:CKV80 RS06055
gene id: 45243:CKV80_RS06055
uniprot id: A0A125S2N2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

45243:CKV80 RS10725
gene id: 45243:CKV80_RS10725
uniprot id: A0A0X8JBX3
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS03070
gene id: 45243:CKV80_RS03070
uniprot id: A0A125S387
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS01705
gene id: 45243:CKV80_RS01705
uniprot id: A0A0X8JB77
names: Similarity
messages: Belongs to the phosphohexose mutase family.

45243:CKV80 RS00870
gene id: 45243:CKV80_RS00870
uniprot id: A0A0X8JBH6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS02830
gene id: 45243:CKV80_RS02830
uniprot id: A0A125S3A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

45243:CKV80 RS00730
gene id: 45243:CKV80_RS00730
uniprot id: A0A0X8JAP1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

45243:CKV80 RS04805
gene id: 45243:CKV80_RS04805
uniprot id: A0A125S2Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS10465
gene id: 45243:CKV80_RS10465
uniprot id: A0A0X8JBE0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

45243:CKV80 RS00335
gene id: 45243:CKV80_RS00335
uniprot id: A0A125S3P9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS08285
gene id: 45243:CKV80_RS08285
uniprot id: A0A125S1J6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

45243:CKV80 RS03025
gene id: 45243:CKV80_RS03025
uniprot id: A0A0X8J9W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

45243:CKV80 RS10185
gene id: 45243:CKV80_RS10185
uniprot id: A0A125S419
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS00220
gene id: 45243:CKV80_RS00220
uniprot id: A0A0X8JAT6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

45243:CKV80 RS09305
gene id: 45243:CKV80_RS09305
uniprot id: A0A0X8JCZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

45243:CKV80 RS11370
gene id: 45243:CKV80_RS11370
uniprot id: A0A0X8JB20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

45243:CKV80 RS04250
gene id: 45243:CKV80_RS04250
uniprot id: A0A125S320
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS03840
gene id: 45243:CKV80_RS03840
uniprot id: A0A0X8J9J8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

45243:CKV80 RS03065
gene id: 45243:CKV80_RS03065
uniprot id: A0A0X8JAI3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

45243:CKV80 RS07795
gene id: 45243:CKV80_RS07795
uniprot id: A0A125S1T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

45243:CKV80 RS06605
gene id: 45243:CKV80_RS06605
uniprot id: A0A125S2E3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

45243:CKV80 RS03250
gene id: 45243:CKV80_RS03250
uniprot id: A0A125S378
names: Similarity
messages: Belongs to the peptidase C40 family.

45243:CKV80 RS08170
gene id: 45243:CKV80_RS08170
uniprot id: A0A125S1L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

45243:CKV80 RS00695
gene id: 45243:CKV80_RS00695
uniprot id: A0A0X8JBA9
names: Similarity
messages: Belongs to the DapA family.

45243:CKV80 RS03615
gene id: 45243:CKV80_RS03615
uniprot id: A0A0X8J9L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

45243:CKV80 RS10340
gene id: 45243:CKV80_RS10340
uniprot id: A0A0X8JBH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

45243:CKV80 RS07340
gene id: 45243:CKV80_RS07340
uniprot id: A0A125S213
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

45243:CKV80 RS04155
gene id: 45243:CKV80_RS04155
uniprot id: A0A0X8J9K1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

45243:CKV80 RS07970
gene id: 45243:CKV80_RS07970
uniprot id: A0A125S1Q2
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS06785
gene id: 45243:CKV80_RS06785
uniprot id: A0A125S2A9
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

45243:CKV80 RS06610
gene id: 45243:CKV80_RS06610
uniprot id: A0A125S2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS05220
gene id: 45243:CKV80_RS05220
uniprot id: A0A125S2W3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

45243:CKV80 RS11120
gene id: 45243:CKV80_RS11120
uniprot id: A0A125S3W5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

45243:CKV80 RS07130
gene id: 45243:CKV80_RS07130
uniprot id: A0A125S250
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

45243:CKV80 RS03540
gene id: 45243:CKV80_RS03540
uniprot id: A0A0X8JAP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

45243:CKV80 RS11210
gene id: 45243:CKV80_RS11210
uniprot id: A0A125S3V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

45243:CKV80 RS10745
gene id: 45243:CKV80_RS10745
uniprot id: A0A0X8JC53
names: Similarity
messages: Belongs to the ClpA/ClpB family.

45243:CKV80 RS03635
gene id: 45243:CKV80_RS03635
uniprot id: A0A0X8JAD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

45243:CKV80 RS09550
gene id: 45243:CKV80_RS09550
uniprot id: A0A125S457
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

45243:CKV80 RS08870
gene id: 45243:CKV80_RS08870
uniprot id: A0A109W1S6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

45243:CKV80 RS00920
gene id: 45243:CKV80_RS00920
uniprot id: A0A125S3L3
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS03510
gene id: 45243:CKV80_RS03510
uniprot id: A0A125S363
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

45243:CKV80 RS06025
gene id: 45243:CKV80_RS06025
uniprot id: A0A125S2N8
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS00985
gene id: 45243:CKV80_RS00985
uniprot id: A0A125S3L0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS00145
gene id: 45243:CKV80_RS00145
uniprot id: A0A125S3R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

45243:CKV80 RS00075
gene id: 45243:CKV80_RS00075
uniprot id: A0A0X8JC97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

45243:CKV80 RS04825
gene id: 45243:CKV80_RS04825
uniprot id: A0A0X8J9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

45243:CKV80 RS08790
gene id: 45243:CKV80_RS08790
uniprot id: A0A120KL70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

45243:CKV80 RS06425
gene id: 45243:CKV80_RS06425
uniprot id: A0A125S2H3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS05215
gene id: 45243:CKV80_RS05215
uniprot id: A0A125S2W4
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS09120
gene id: 45243:CKV80_RS09120
uniprot id: A0A125S481
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

45243:CKV80 RS01520
gene id: 45243:CKV80_RS01520
uniprot id: A0A0X8JB18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

45243:CKV80 RS04930
gene id: 45243:CKV80_RS04930
uniprot id: A0A0X8J9X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

45243:CKV80 RS09780
gene id: 45243:CKV80_RS09780
uniprot id: A0A0X8JC85
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS03650
gene id: 45243:CKV80_RS03650
uniprot id: A0A0X8J9P5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS07935
gene id: 45243:CKV80_RS07935
uniprot id: A0A125S1Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS10115
gene id: 45243:CKV80_RS10115
uniprot id: A0A0X8JC45
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS11830
gene id: 45243:CKV80_RS11830
uniprot id: A0A0X8JBK4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

45243:CKV80 RS11700
gene id: 45243:CKV80_RS11700
uniprot id: A0A0X8JAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

45243:CKV80 RS01745
gene id: 45243:CKV80_RS01745
uniprot id: A0A0X8JAB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

45243:CKV80 RS09390
gene id: 45243:CKV80_RS09390
uniprot id: A0A0X8JBS6
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

45243:CKV80 RS04955
gene id: 45243:CKV80_RS04955
uniprot id: A0A0X8J9F9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

45243:CKV80 RS08020
gene id: 45243:CKV80_RS08020
uniprot id: A0A0X8JC52
names: Similarity
messages: Belongs to the UPF0758 family.

45243:CKV80 RS01320
gene id: 45243:CKV80_RS01320
uniprot id: A0A0X8JAG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

45243:CKV80 RS00215
gene id: 45243:CKV80_RS00215
uniprot id: A0A0X8JAU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

45243:CKV80 RS10245
gene id: 45243:CKV80_RS10245
uniprot id: A0A109W1X8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS11705
gene id: 45243:CKV80_RS11705
uniprot id: A0A0X8JB01
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

45243:CKV80 RS08820
gene id: 45243:CKV80_RS08820
uniprot id: A0A0X8JBZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

45243:CKV80 RS11695
gene id: 45243:CKV80_RS11695
uniprot id: A0A0X8JD59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

45243:CKV80 RS11040
gene id: 45243:CKV80_RS11040
uniprot id: A0A125S3X1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS11640
gene id: 45243:CKV80_RS11640
uniprot id: A0A125S3T2
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS07325
gene id: 45243:CKV80_RS07325
uniprot id: A0A125S215
names: Similarity
messages: Belongs to the SufE family.

45243:CKV80 RS01325
gene id: 45243:CKV80_RS01325
uniprot id: A0A125S3J1
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

45243:CKV80 RS01640
gene id: 45243:CKV80_RS01640
uniprot id: A0A0X8JAB2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

45243:CKV80 RS02425
gene id: 45243:CKV80_RS02425
uniprot id: A0A0X8JB14
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

45243:CKV80 RS04830
gene id: 45243:CKV80_RS04830
uniprot id: A0A125S2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

45243:CKV80 RS05600
gene id: 45243:CKV80_RS05600
uniprot id: A0A0X8J9B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

45243:CKV80 RS03600
gene id: 45243:CKV80_RS03600
uniprot id: A0A0X8JAC3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

45243:CKV80 RS05015
gene id: 45243:CKV80_RS05015
uniprot id: A0A0X8JA76
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

45243:CKV80 RS09350
gene id: 45243:CKV80_RS09350
uniprot id: A0A0X8JBS8
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS03265
gene id: 45243:CKV80_RS03265
uniprot id: A0A0X8J9P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

45243:CKV80 RS08895
gene id: 45243:CKV80_RS08895
uniprot id: A0A0X8JBY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

45243:CKV80 RS01150
gene id: 45243:CKV80_RS01150
uniprot id: A0A125S3K1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

45243:CKV80 RS08860
gene id: 45243:CKV80_RS08860
uniprot id: A0A0X8JBZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

45243:CKV80 RS09190
gene id: 45243:CKV80_RS09190
uniprot id: A0A0X8JCN9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

45243:CKV80 RS03995
gene id: 45243:CKV80_RS03995
uniprot id: A0A125S333
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

45243:CKV80 RS08335
gene id: 45243:CKV80_RS08335
uniprot id: A0A125S1I8
names: Similarity
messages: Belongs to the YoeB family.

45243:CKV80 RS08345
gene id: 45243:CKV80_RS08345
uniprot id: A0A125S1I7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS03710
gene id: 45243:CKV80_RS03710
uniprot id: A0A0X8JAC0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

45243:CKV80 RS02185
gene id: 45243:CKV80_RS02185
uniprot id: A0A0X8JA64
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

45243:CKV80 RS01180
gene id: 45243:CKV80_RS01180
uniprot id: A0A0X8JAE2
names: Similarity
messages: Belongs to the UPF0102 family.

45243:CKV80 RS02215
gene id: 45243:CKV80_RS02215
uniprot id: A0A0X8JC93
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

45243:CKV80 RS00890
gene id: 45243:CKV80_RS00890
uniprot id: A0A0X8JAK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

45243:CKV80 RS11050
gene id: 45243:CKV80_RS11050
uniprot id: A0A125S3W9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

45243:CKV80 RS08640
gene id: 45243:CKV80_RS08640
uniprot id: A0A0X8JC20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

45243:CKV80 RS04505
gene id: 45243:CKV80_RS04505
uniprot id: A0A125S306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

45243:CKV80 RS00040
gene id: 45243:CKV80_RS00040
uniprot id: A0A0X8JAW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

45243:CKV80 RS05130
gene id: 45243:CKV80_RS05130
uniprot id: A0A125S2X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

45243:CKV80 RS08245
gene id: 45243:CKV80_RS08245
uniprot id: A0A125S1K3
names: Similarity
messages: Belongs to the LOG family.

45243:CKV80 RS06670
gene id: 45243:CKV80_RS06670
uniprot id: A0A125S2D0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

45243:CKV80 RS01155
gene id: 45243:CKV80_RS01155
uniprot id: A0A125S3K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

45243:CKV80 RS02170
gene id: 45243:CKV80_RS02170
uniprot id: A0A0X8JA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS07850
gene id: 45243:CKV80_RS07850
uniprot id: A0A125S1S1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

45243:CKV80 RS04280
gene id: 45243:CKV80_RS04280
uniprot id: A0A125S317
names: Similarity
messages: Belongs to the EPSP synthase family.

45243:CKV80 RS00190
gene id: 45243:CKV80_RS00190
uniprot id: A0A0X8JAR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

45243:CKV80 RS08985
gene id: 45243:CKV80_RS08985
uniprot id: A0A0X8JBX5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS11545
gene id: 45243:CKV80_RS11545
uniprot id: A0A125S3T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

45243:CKV80 RS06020
gene id: 45243:CKV80_RS06020
uniprot id: A0A125S2N9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

45243:CKV80 RS10805
gene id: 45243:CKV80_RS10805
uniprot id: A0A0X8JBW5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

45243:CKV80 RS04115
gene id: 45243:CKV80_RS04115
uniprot id: A0A109W1V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

45243:CKV80 RS08835
gene id: 45243:CKV80_RS08835
uniprot id: A0A0X8JCT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

45243:CKV80 RS11170
gene id: 45243:CKV80_RS11170
uniprot id: A0A0X8JB55
names: Similarity
messages: Belongs to the peptidase M13 family.

45243:CKV80 RS10190
gene id: 45243:CKV80_RS10190
uniprot id: A0A125S418
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

45243:CKV80 RS01195
gene id: 45243:CKV80_RS01195
uniprot id: A0A0X8JBC6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

45243:CKV80 RS08830
gene id: 45243:CKV80_RS08830
uniprot id: A0A0X8JCU5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

45243:CKV80 RS04135
gene id: 45243:CKV80_RS04135
uniprot id: A0A0X8JA69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

45243:CKV80 RS08720
gene id: 45243:CKV80_RS08720
uniprot id: A0A120KM75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

45243:CKV80 RS06045
gene id: 45243:CKV80_RS06045
uniprot id: A0A125S2N4
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS08845
gene id: 45243:CKV80_RS08845
uniprot id: A0A0X8JBY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

45243:CKV80 RS01435
gene id: 45243:CKV80_RS01435
uniprot id: A0A0X8JAA6
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

45243:CKV80 RS07415
gene id: 45243:CKV80_RS07415
uniprot id: A0A125S1Z9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

45243:CKV80 RS03985
gene id: 45243:CKV80_RS03985
uniprot id: A0A125S335
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

45243:CKV80 RS11355
gene id: 45243:CKV80_RS11355
uniprot id: A0A0X8JB41
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

45243:CKV80 RS00750
gene id: 45243:CKV80_RS00750
uniprot id: A0A125S3M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS01820
gene id: 45243:CKV80_RS01820
uniprot id: A0A0X8JAA5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

45243:CKV80 RS08605
gene id: 45243:CKV80_RS08605
uniprot id: A0A109W1T6
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

45243:CKV80 RS05195
gene id: 45243:CKV80_RS05195
uniprot id: A0A0X8J9E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

45243:CKV80 RS09800
gene id: 45243:CKV80_RS09800
uniprot id: A0A0X8JC88
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

45243:CKV80 RS05265
gene id: 45243:CKV80_RS05265
uniprot id: A0A0X8J9D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

45243:CKV80 RS04470
gene id: 45243:CKV80_RS04470
uniprot id: A0A0X8JAD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS11825
gene id: 45243:CKV80_RS11825
uniprot id: A0A125S3S3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

45243:CKV80 RS10755
gene id: 45243:CKV80_RS10755
uniprot id: A0A0X8JBW7
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS10150
gene id: 45243:CKV80_RS10150
uniprot id: A0A0X8JC35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

45243:CKV80 RS02330
gene id: 45243:CKV80_RS02330
uniprot id: A0A125S3D2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

45243:CKV80 RS06455
gene id: 45243:CKV80_RS06455
uniprot id: A0A125S2G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

45243:CKV80 RS01620
gene id: 45243:CKV80_RS01620
uniprot id: A0A0X8JB88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

45243:CKV80 RS05460
gene id: 45243:CKV80_RS05460
uniprot id: A0A125S2V0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS06330
gene id: 45243:CKV80_RS06330
uniprot id: A0A125S2J1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

45243:CKV80 RS05095
gene id: 45243:CKV80_RS05095
uniprot id: A0A0X8J9W4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

45243:CKV80 RS09025
gene id: 45243:CKV80_RS09025
uniprot id: A0A0X8JBW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

45243:CKV80 RS05930
gene id: 45243:CKV80_RS05930
uniprot id: A0A125S2Q4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

45243:CKV80 RS01675
gene id: 45243:CKV80_RS01675
uniprot id: A0A125S3G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

45243:CKV80 RS07980
gene id: 45243:CKV80_RS07980
uniprot id: A0A125S1Q0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

45243:CKV80 RS11790
gene id: 45243:CKV80_RS11790
uniprot id: A0A0X8JAY2
names: Similarity
messages: Belongs to the YoeB family.

45243:CKV80 RS11340
gene id: 45243:CKV80_RS11340
uniprot id: A0A0X8JBY1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

45243:CKV80 RS11500
gene id: 45243:CKV80_RS11500
uniprot id: A0A0X8JBW2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

45243:CKV80 RS04015
gene id: 45243:CKV80_RS04015
uniprot id: A0A0X8J9I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

45243:CKV80 RS04720
gene id: 45243:CKV80_RS04720
uniprot id: A0A125S2Z6
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

45243:CKV80 RS10795
gene id: 45243:CKV80_RS10795
uniprot id: A0A125S3Y3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

45243:CKV80 RS07440
gene id: 45243:CKV80_RS07440
uniprot id: A0A125S1Z4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

45243:CKV80 RS09735
gene id: 45243:CKV80_RS09735
uniprot id: A0A0X8JBM9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

45243:CKV80 RS11605
gene id: 45243:CKV80_RS11605
uniprot id: A0A0X8JAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

45243:CKV80 RS03405
gene id: 45243:CKV80_RS03405
uniprot id: A0A125S370
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

45243:CKV80 RS06060
gene id: 45243:CKV80_RS06060
uniprot id: A0A125S2N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

45243:CKV80 RS08855
gene id: 45243:CKV80_RS08855
uniprot id: A0A0X8JBY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

45243:CKV80 RS06100
gene id: 45243:CKV80_RS06100
uniprot id: A0A125S2M3
names: Similarity
messages: Belongs to the GARS family.

45243:CKV80 RS01265
gene id: 45243:CKV80_RS01265
uniprot id: A0A0X8JB40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

45243:CKV80 RS11025
gene id: 45243:CKV80_RS11025
uniprot id: A0A0X8JB90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

45243:CKV80 RS11405
gene id: 45243:CKV80_RS11405
uniprot id: A0A125S3U7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

45243:CKV80 RS01775
gene id: 45243:CKV80_RS01775
uniprot id: A0A125S3G2
names: Similarity
messages: Belongs to the ribF family.

45243:CKV80 RS06295
gene id: 45243:CKV80_RS06295
uniprot id: A0A125S2J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

45243:CKV80 RS09785
gene id: 45243:CKV80_RS09785
uniprot id: A0A125S442
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS10400
gene id: 45243:CKV80_RS10400
uniprot id: A0A0X8JC03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

45243:CKV80 RS07700
gene id: 45243:CKV80_RS07700
uniprot id: A0A125S1U8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

45243:CKV80 RS09145
gene id: 45243:CKV80_RS09145
uniprot id: A0A125S477
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

45243:CKV80 RS02345
gene id: 45243:CKV80_RS02345
uniprot id: A0A0X8JB22
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

45243:CKV80 RS11875
gene id: 45243:CKV80_RS11875
uniprot id: A0A0X8JAW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

45243:CKV80 RS03440
gene id: 45243:CKV80_RS03440
uniprot id: A0A0X8JAD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

45243:CKV80 RS08460
gene id: 45243:CKV80_RS08460
uniprot id: A0A109W748
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

45243:CKV80 RS05315
gene id: 45243:CKV80_RS05315
uniprot id: A0A0X8J9B0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

45243:CKV80 RS11595
gene id: 45243:CKV80_RS11595
uniprot id: A0A0X8JB05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS00320
gene id: 45243:CKV80_RS00320
uniprot id: A0A125S3Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS04935
gene id: 45243:CKV80_RS04935
uniprot id: A0A0X8JA91
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

45243:CKV80 RS11860
gene id: 45243:CKV80_RS11860
uniprot id: A0A0X8JBI2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

45243:CKV80 RS08865
gene id: 45243:CKV80_RS08865
uniprot id: A0A109W1S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

45243:CKV80 RS08815
gene id: 45243:CKV80_RS08815
uniprot id: A0A109W1S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

45243:CKV80 RS03345
gene id: 45243:CKV80_RS03345
uniprot id: A0A125S372
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

45243:CKV80 RS03515
gene id: 45243:CKV80_RS03515
uniprot id: A0A0X8JAD6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

45243:CKV80 RS10985
gene id: 45243:CKV80_RS10985
uniprot id: A0A0X8JBV1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

45243:CKV80 RS07640
gene id: 45243:CKV80_RS07640
uniprot id: A0A125S1V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

45243:CKV80 RS11430
gene id: 45243:CKV80_RS11430
uniprot id: A0A0X8JBN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

45243:CKV80 RS09180
gene id: 45243:CKV80_RS09180
uniprot id: A0A0X8JCF7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS07370
gene id: 45243:CKV80_RS07370
uniprot id: A0A125S208
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS10110
gene id: 45243:CKV80_RS10110
uniprot id: A0A125S423
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS01495
gene id: 45243:CKV80_RS01495
uniprot id: A0A0X8JC95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

45243:CKV80 RS07095
gene id: 45243:CKV80_RS07095
uniprot id: A0A125S257
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS07770
gene id: 45243:CKV80_RS07770
uniprot id: A0A125S1T5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

45243:CKV80 RS10415
gene id: 45243:CKV80_RS10415
uniprot id: A0A0X8JBF3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

45243:CKV80 RS00770
gene id: 45243:CKV80_RS00770
uniprot id: A0A0X8JAJ2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

45243:CKV80 RS11765
gene id: 45243:CKV80_RS11765
uniprot id: A0A0X8JBJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

45243:CKV80 RS01355
gene id: 45243:CKV80_RS01355
uniprot id: A0A125S3I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

45243:CKV80 RS08630
gene id: 45243:CKV80_RS08630
uniprot id: A0A0X8JCM6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

45243:CKV80 RS04865
gene id: 45243:CKV80_RS04865
uniprot id: A0A0X8J9Z0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

45243:CKV80 RS02350
gene id: 45243:CKV80_RS02350
uniprot id: A0A0X8JB23
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

45243:CKV80 RS05840
gene id: 45243:CKV80_RS05840
uniprot id: A0A125S2S1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS03730
gene id: 45243:CKV80_RS03730
uniprot id: A0A0X8J9N6
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS01210
gene id: 45243:CKV80_RS01210
uniprot id: A0A0X8JAG8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

45243:CKV80 RS07740
gene id: 45243:CKV80_RS07740
uniprot id: A0A125S1U1
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS08260
gene id: 45243:CKV80_RS08260
uniprot id: A0A125S1K0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS02195
gene id: 45243:CKV80_RS02195
uniprot id: A0A125S3E0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

45243:CKV80 RS04060
gene id: 45243:CKV80_RS04060
uniprot id: A0A0X8J9K6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

45243:CKV80 RS05685
gene id: 45243:CKV80_RS05685
uniprot id: A0A0X8J9B4
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS05585
gene id: 45243:CKV80_RS05585
uniprot id: A0A0X8JA14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

45243:CKV80 RS03655
gene id: 45243:CKV80_RS03655
uniprot id: A0A0X8J9P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

45243:CKV80 RS03245
gene id: 45243:CKV80_RS03245
uniprot id: A0A125S379
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS11835
gene id: 45243:CKV80_RS11835
uniprot id: A0A125S3S2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

45243:CKV80 RS02895
gene id: 45243:CKV80_RS02895
uniprot id: A0A125S3A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

45243:CKV80 RS09955
gene id: 45243:CKV80_RS09955
uniprot id: A0A0X8JBK2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

45243:CKV80 RS06355
gene id: 45243:CKV80_RS06355
uniprot id: A0A125S2I6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

45243:CKV80 RS08840
gene id: 45243:CKV80_RS08840
uniprot id: A0A0X8JCJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

45243:CKV80 RS03480
gene id: 45243:CKV80_RS03480
uniprot id: A0A0X8J9R8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

45243:CKV80 RS08775
gene id: 45243:CKV80_RS08775
uniprot id: A0A0X8JBZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

45243:CKV80 RS08565
gene id: 45243:CKV80_RS08565
uniprot id: A0A0X8JCX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

45243:CKV80 RS11890
gene id: 45243:CKV80_RS11890
uniprot id: A0A125S3S0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

45243:CKV80 RS02240
gene id: 45243:CKV80_RS02240
uniprot id: A0A0X8JA15
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS01920
gene id: 45243:CKV80_RS01920
uniprot id: A0A125S3F3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS08785
gene id: 45243:CKV80_RS08785
uniprot id: A0A0X8JC04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

45243:CKV80 RS01760
gene id: 45243:CKV80_RS01760
uniprot id: A0A125S3G4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS02730
gene id: 45243:CKV80_RS02730
uniprot id: A0A125S3A9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

45243:CKV80 RS03330
gene id: 45243:CKV80_RS03330
uniprot id: A0A125S373
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

45243:CKV80 RS03005
gene id: 45243:CKV80_RS03005
uniprot id: A0A0X8JAU8
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS00005
gene id: 45243:CKV80_RS00005
uniprot id: A0A125S3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

45243:CKV80 RS01795
gene id: 45243:CKV80_RS01795
uniprot id: A0A0X8JB70
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

45243:CKV80 RS04200
gene id: 45243:CKV80_RS04200
uniprot id: A0A0X8JA48
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

45243:CKV80 RS11350
gene id: 45243:CKV80_RS11350
uniprot id: A0A0X8JBP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

45243:CKV80 RS02000
gene id: 45243:CKV80_RS02000
uniprot id: A0A125S3E9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

45243:CKV80 RS08635
gene id: 45243:CKV80_RS08635
uniprot id: A0A109W1T0
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS06725
gene id: 45243:CKV80_RS06725
uniprot id: A0A125S2C0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

45243:CKV80 RS02880
gene id: 45243:CKV80_RS02880
uniprot id: A0A0X8J9X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

45243:CKV80 RS07515
gene id: 45243:CKV80_RS07515
uniprot id: A0A125S1Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

45243:CKV80 RS00915
gene id: 45243:CKV80_RS00915
uniprot id: A0A125S3L4
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS10600
gene id: 45243:CKV80_RS10600
uniprot id: A0A0X8JBC9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

45243:CKV80 RS05305
gene id: 45243:CKV80_RS05305
uniprot id: A0A0X8J9T4
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS06075
gene id: 45243:CKV80_RS06075
uniprot id: A0A125S2M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

45243:CKV80 RS05275
gene id: 45243:CKV80_RS05275
uniprot id: A0A0X8J9D6
names: Similarity
messages: Belongs to the thioredoxin family.

45243:CKV80 RS08685
gene id: 45243:CKV80_RS08685
uniprot id: A0A0X8JC11
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

45243:CKV80 RS03810
gene id: 45243:CKV80_RS03810
uniprot id: A0A125S346
names: Similarity
messages: Belongs to the peptidase S49 family.

45243:CKV80 RS01170
gene id: 45243:CKV80_RS01170
uniprot id: A0A0X8JB56
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

45243:CKV80 RS08770
gene id: 45243:CKV80_RS08770
uniprot id: A0A0X8JC01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

45243:CKV80 RS00015
gene id: 45243:CKV80_RS00015
uniprot id: A0A0X8JBI7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

45243:CKV80 RS07115
gene id: 45243:CKV80_RS07115
uniprot id: A0A125S253
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

45243:CKV80 RS06015
gene id: 45243:CKV80_RS06015
uniprot id: A0A125S2P0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

45243:CKV80 RS03740
gene id: 45243:CKV80_RS03740
uniprot id: A0A125S350
names: Similarity
messages: Belongs to the heat shock protein 90 family.

45243:CKV80 RS11865
gene id: 45243:CKV80_RS11865
uniprot id: A0A0X8JAX7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

45243:CKV80 RS11125
gene id: 45243:CKV80_RS11125
uniprot id: A0A125S3W4
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

45243:CKV80 RS10320
gene id: 45243:CKV80_RS10320
uniprot id: A0A0X8JC13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS11290
gene id: 45243:CKV80_RS11290
uniprot id: A0A125S3V5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS00480
gene id: 45243:CKV80_RS00480
uniprot id: A0A0X8JAP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

45243:CKV80 RS11575
gene id: 45243:CKV80_RS11575
uniprot id: A0A0X8JBM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

45243:CKV80 RS01790
gene id: 45243:CKV80_RS01790
uniprot id: A0A0X8JB73
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

45243:CKV80 RS00435
gene id: 45243:CKV80_RS00435
uniprot id: A0A0X8JAN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

45243:CKV80 RS04915
gene id: 45243:CKV80_RS04915
uniprot id: A0A125S2Y2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

45243:CKV80 RS03560
gene id: 45243:CKV80_RS03560
uniprot id: A0A0X8J9Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

45243:CKV80 RS07215
gene id: 45243:CKV80_RS07215
uniprot id: A0A125S235
names: Similarity
messages: Belongs to the UPF0310 family.

45243:CKV80 RS04045
gene id: 45243:CKV80_RS04045
uniprot id: A0A0X8J9K9
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS08375
gene id: 45243:CKV80_RS08375
uniprot id: A0A125S1I1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS03805
gene id: 45243:CKV80_RS03805
uniprot id: A0A0X8J9M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS01680
gene id: 45243:CKV80_RS01680
uniprot id: A0A125S3G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

45243:CKV80 RS10205
gene id: 45243:CKV80_RS10205
uniprot id: A0A125S417
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

45243:CKV80 RS02310
gene id: 45243:CKV80_RS02310
uniprot id: A0A125S3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

45243:CKV80 RS01830
gene id: 45243:CKV80_RS01830
uniprot id: A0A125S3G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

45243:CKV80 RS07540
gene id: 45243:CKV80_RS07540
uniprot id: A0A125S1X6
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS05595
gene id: 45243:CKV80_RS05595
uniprot id: A0A0X8J9R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

45243:CKV80 RS05990
gene id: 45243:CKV80_RS05990
uniprot id: A0A125S2P4
names: Similarity
messages: Belongs to the histone deacetylase family.

45243:CKV80 RS02935
gene id: 45243:CKV80_RS02935
uniprot id: A0A0X8JAW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

45243:CKV80 RS10195
gene id: 45243:CKV80_RS10195
uniprot id: A0A0X8JC37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

45243:CKV80 RS04265
gene id: 45243:CKV80_RS04265
uniprot id: A0A125S318
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

45243:CKV80 RS05535
gene id: 45243:CKV80_RS05535
uniprot id: A0A0X8J9C3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

45243:CKV80 RS03725
gene id: 45243:CKV80_RS03725
uniprot id: A0A0X8J9N5
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS09730
gene id: 45243:CKV80_RS09730
uniprot id: A0A0X8JC87
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS09665
gene id: 45243:CKV80_RS09665
uniprot id: A0A0X8JBP1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

45243:CKV80 RS11840
gene id: 45243:CKV80_RS11840
uniprot id: A0A0X8JAU7
names: Similarity
messages: Belongs to the DprA/Smf family.

45243:CKV80 RS10020
gene id: 45243:CKV80_RS10020
uniprot id: A0A125S428
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

45243:CKV80 RS02790
gene id: 45243:CKV80_RS02790
uniprot id: A0A0X8JAM7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

45243:CKV80 RS03825
gene id: 45243:CKV80_RS03825
uniprot id: A0A125S343
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

45243:CKV80 RS09845
gene id: 45243:CKV80_RS09845
uniprot id: A0A125S440
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

45243:CKV80 RS10410
gene id: 45243:CKV80_RS10410
uniprot id: A0A0X8JBF8
names: Similarity
messages: Belongs to the UPF0173 family.

45243:CKV80 RS00360
gene id: 45243:CKV80_RS00360
uniprot id: A0A0X8JBE4
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

45243:CKV80 RS07375
gene id: 45243:CKV80_RS07375
uniprot id: A0A125S207
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

45243:CKV80 RS05895
gene id: 45243:CKV80_RS05895
uniprot id: A0A125S2R1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

45243:CKV80 RS02885
gene id: 45243:CKV80_RS02885
uniprot id: A0A0X8J9X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

45243:CKV80 RS04715
gene id: 45243:CKV80_RS04715
uniprot id: A0A0X8J9H1
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

45243:CKV80 RS04075
gene id: 45243:CKV80_RS04075
uniprot id: A0A125S329
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

45243:CKV80 RS11620
gene id: 45243:CKV80_RS11620
uniprot id: A0A125S3T5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-55 and Arg-58) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

45243:CKV80 RS03385
gene id: 45243:CKV80_RS03385
uniprot id: A0A0X8J9S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

45243:CKV80 RS07650
gene id: 45243:CKV80_RS07650
uniprot id: A0A125S1V7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

45243:CKV80 RS01250
gene id: 45243:CKV80_RS01250
uniprot id: A0A125S3J2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

45243:CKV80 RS04545
gene id: 45243:CKV80_RS04545
uniprot id: A0A0X8JA13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS09430
gene id: 45243:CKV80_RS09430
uniprot id: A0A0X8JCD6
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

45243:CKV80 RS00505
gene id: 45243:CKV80_RS00505
uniprot id: A0A125S3P0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

45243:CKV80 RS04295
gene id: 45243:CKV80_RS04295
uniprot id: A0A0X8JAF5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

45243:CKV80 RS04085
gene id: 45243:CKV80_RS04085
uniprot id: A0A0X8JA67
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

45243:CKV80 RS05950
gene id: 45243:CKV80_RS05950
uniprot id: A0A125S2Q1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

45243:CKV80 RS00135
gene id: 45243:CKV80_RS00135
uniprot id: A0A0X8JAU1
names: Similarity
messages: Belongs to the CapA family.

45243:CKV80 RS01445
gene id: 45243:CKV80_RS01445
uniprot id: A0A0X8JBA4
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS08270
gene id: 45243:CKV80_RS08270
uniprot id: A0A125S1J8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

45243:CKV80 RS11480
gene id: 45243:CKV80_RS11480
uniprot id: A0A125S3U2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

45243:CKV80 RS09600
gene id: 45243:CKV80_RS09600
uniprot id: A0A0X8JBQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

45243:CKV80 RS05850
gene id: 45243:CKV80_RS05850
uniprot id: A0A125S2R9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

45243:CKV80 RS07720
gene id: 45243:CKV80_RS07720
uniprot id: A0A125S1U5
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

45243:CKV80 RS06245
gene id: 45243:CKV80_RS06245
uniprot id: A0A125S2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS10345
gene id: 45243:CKV80_RS10345
uniprot id: A0A0X8JBG1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

45243:CKV80 RS10665
gene id: 45243:CKV80_RS10665
uniprot id: A0A0X8JC67
names: Similarity
messages: Belongs to the asparaginase 1 family.

45243:CKV80 RS04760
gene id: 45243:CKV80_RS04760
uniprot id: A0A0X8J9Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

45243:CKV80 RS11755
gene id: 45243:CKV80_RS11755
uniprot id: A0A0X8JBU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

45243:CKV80 RS11775
gene id: 45243:CKV80_RS11775
uniprot id: A0A0X8JCV8
names: Similarity
messages: Belongs to the ArsC family.

45243:CKV80 RS01390
gene id: 45243:CKV80_RS01390
uniprot id: A0A0X8JAE4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

45243:CKV80 RS11845
gene id: 45243:CKV80_RS11845
uniprot id: A0A0X8JBJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS11245
gene id: 45243:CKV80_RS11245
uniprot id: A0A0X8JBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

45243:CKV80 RS07040
gene id: 45243:CKV80_RS07040
uniprot id: A0A125S269
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

45243:CKV80 RS09995
gene id: 45243:CKV80_RS09995
uniprot id: A0A0X8JBK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS03775
gene id: 45243:CKV80_RS03775
uniprot id: A0A0X8JAL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS04580
gene id: 45243:CKV80_RS04580
uniprot id: A0A0X8J9H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

45243:CKV80 RS00100
gene id: 45243:CKV80_RS00100
uniprot id: A0A0X8JBH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

45243:CKV80 RS07865
gene id: 45243:CKV80_RS07865
uniprot id: A0A125S1R9
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

45243:CKV80 RS03240
gene id: 45243:CKV80_RS03240
uniprot id: A0A125S380
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

45243:CKV80 RS05565
gene id: 45243:CKV80_RS05565
uniprot id: A0A0X8J9Q6
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS03350
gene id: 45243:CKV80_RS03350
uniprot id: A0A0X8J9N9
names: Similarity
messages: Belongs to the aldose epimerase family.

45243:CKV80 RS00085
gene id: 45243:CKV80_RS00085
uniprot id: A0A0X8JBI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

45243:CKV80 RS05075
gene id: 45243:CKV80_RS05075
uniprot id: A0A0X8J9C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

45243:CKV80 RS11850
gene id: 45243:CKV80_RS11850
uniprot id: A0A0X8JBT1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS01550
gene id: 45243:CKV80_RS01550
uniprot id: A0A0X8JB08
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

45243:CKV80 RS08470
gene id: 45243:CKV80_RS08470
uniprot id: A0A120KKS1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

45243:CKV80 RS04375
gene id: 45243:CKV80_RS04375
uniprot id: A0A125S312
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

45243:CKV80 RS05285
gene id: 45243:CKV80_RS05285
uniprot id: A0A125S2W1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

45243:CKV80 RS03225
gene id: 45243:CKV80_RS03225
uniprot id: A0A0X8J9U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

45243:CKV80 RS11135
gene id: 45243:CKV80_RS11135
uniprot id: A0A125S3W3
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS06890
gene id: 45243:CKV80_RS06890
uniprot id: A0A125S292
names: Similarity
messages: Belongs to the Skp family.

45243:CKV80 RS07335
gene id: 45243:CKV80_RS07335
uniprot id: A0A0X8JC38
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS09765
gene id: 45243:CKV80_RS09765
uniprot id: A0A125S444
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

45243:CKV80 RS00025
gene id: 45243:CKV80_RS00025
uniprot id: A0A0X8JBR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

45243:CKV80 RS05730
gene id: 45243:CKV80_RS05730
uniprot id: A0A125S2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS09435
gene id: 45243:CKV80_RS09435
uniprot id: A0A125S463
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

45243:CKV80 RS00895
gene id: 45243:CKV80_RS00895
uniprot id: A0A0X8JAK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

45243:CKV80 RS02705
gene id: 45243:CKV80_RS02705
uniprot id: A0A0X8J9Z5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

45243:CKV80 RS10590
gene id: 45243:CKV80_RS10590
uniprot id: A0A0X8JBD2
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS00010
gene id: 45243:CKV80_RS00010
uniprot id: A0A0X8JAT4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

45243:CKV80 RS07550
gene id: 45243:CKV80_RS07550
uniprot id: A0A125S1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

45243:CKV80 RS00825
gene id: 45243:CKV80_RS00825
uniprot id: A0A0X8JAN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

45243:CKV80 RS05985
gene id: 45243:CKV80_RS05985
uniprot id: A0A125S2P5
names: Similarity
messages: Belongs to the TPP enzyme family.

45243:CKV80 RS01895
gene id: 45243:CKV80_RS01895
uniprot id: A0A0X8JA90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

45243:CKV80 RS04815
gene id: 45243:CKV80_RS04815
uniprot id: A0A125S2Y9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

45243:CKV80 RS08310
gene id: 45243:CKV80_RS08310
uniprot id: A0A125S1J2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

45243:CKV80 RS07350
gene id: 45243:CKV80_RS07350
uniprot id: A0A125S211
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

45243:CKV80 RS08805
gene id: 45243:CKV80_RS08805
uniprot id: A0A109W1T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

45243:CKV80 RS10170
gene id: 45243:CKV80_RS10170
uniprot id: A0A0X8JBI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

45243:CKV80 RS10350
gene id: 45243:CKV80_RS10350
uniprot id: A0A125S411
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

45243:CKV80 RS01350
gene id: 45243:CKV80_RS01350
uniprot id: A0A0X8JB46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

45243:CKV80 RS01230
gene id: 45243:CKV80_RS01230
uniprot id: A0A125S3J5
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

45243:CKV80 RS07585
gene id: 45243:CKV80_RS07585
uniprot id: A0A125S1W8
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

45243:CKV80 RS10515
gene id: 45243:CKV80_RS10515
uniprot id: A0A125S401
names: Similarity
messages: Belongs to the RutC family.

45243:CKV80 RS09700
gene id: 45243:CKV80_RS09700
uniprot id: A0A0X8JC96
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

45243:CKV80 RS04275
gene id: 45243:CKV80_RS04275
uniprot id: A0A0X8JA47
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS10335
gene id: 45243:CKV80_RS10335
uniprot id: A0A0X8JBG7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

45243:CKV80 RS04870
gene id: 45243:CKV80_RS04870
uniprot id: A0A0X8J9G2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

45243:CKV80 RS05325
gene id: 45243:CKV80_RS05325
uniprot id: A0A0X8JA42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS04140
gene id: 45243:CKV80_RS04140
uniprot id: A0A0X8J9K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

45243:CKV80 RS00430
gene id: 45243:CKV80_RS00430
uniprot id: A0A125S3P2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS10910
gene id: 45243:CKV80_RS10910
uniprot id: A0A0X8JC34
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

45243:CKV80 RS06550
gene id: 45243:CKV80_RS06550
uniprot id: A0A125S2F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

45243:CKV80 RS04080
gene id: 45243:CKV80_RS04080
uniprot id: A0A125S328
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

45243:CKV80 RS07530
gene id: 45243:CKV80_RS07530
uniprot id: A0A125S1X8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

45243:CKV80 RS00050
gene id: 45243:CKV80_RS00050
uniprot id: A0A0X8JAX3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

45243:CKV80 RS03835
gene id: 45243:CKV80_RS03835
uniprot id: A0A125S342
names: Similarity
messages: Belongs to the DtxR/MntR family.

45243:CKV80 RS05965
gene id: 45243:CKV80_RS05965
uniprot id: A0A125S2P9
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

45243:CKV80 RS05085
gene id: 45243:CKV80_RS05085
uniprot id: A0A0X8JA71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

45243:CKV80 RS08290
gene id: 45243:CKV80_RS08290
uniprot id: A0A125S1J5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

45243:CKV80 RS10630
gene id: 45243:CKV80_RS10630
uniprot id: A0A0X8JBY5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

45243:CKV80 RS09880
gene id: 45243:CKV80_RS09880
uniprot id: A0A0X8JCF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

45243:CKV80 RS03430
gene id: 45243:CKV80_RS03430
uniprot id: A0A125S367
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS05080
gene id: 45243:CKV80_RS05080
uniprot id: A0A0X8J9V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

45243:CKV80 RS10675
gene id: 45243:CKV80_RS10675
uniprot id: A0A0X8JBX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

45243:CKV80 RS06150
gene id: 45243:CKV80_RS06150
uniprot id: A0A125S2L8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

45243:CKV80 RS03130
gene id: 45243:CKV80_RS03130
uniprot id: A0A0X8J9V3
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS07135
gene id: 45243:CKV80_RS07135
uniprot id: A0A125S249
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

45243:CKV80 RS08615
gene id: 45243:CKV80_RS08615
uniprot id: A0A109W1T5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

45243:CKV80 RS10355
gene id: 45243:CKV80_RS10355
uniprot id: A0A125S410
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

45243:CKV80 RS09720
gene id: 45243:CKV80_RS09720
uniprot id: A0A0X8JCI0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

45243:CKV80 RS08765
gene id: 45243:CKV80_RS08765
uniprot id: A0A0X8JBZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

45243:CKV80 RS09620
gene id: 45243:CKV80_RS09620
uniprot id: A0A125S453
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS08320
gene id: 45243:CKV80_RS08320
uniprot id: A0A125S1J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

45243:CKV80 RS07600
gene id: 45243:CKV80_RS07600
uniprot id: A0A125S1W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

45243:CKV80 RS10140
gene id: 45243:CKV80_RS10140
uniprot id: A0A0X8JCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

45243:CKV80 RS10690
gene id: 45243:CKV80_RS10690
uniprot id: A0A0X8JBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

45243:CKV80 RS05035
gene id: 45243:CKV80_RS05035
uniprot id: A0A0X8J9F1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

45243:CKV80 RS05495
gene id: 45243:CKV80_RS05495
uniprot id: A0A125S2U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

45243:CKV80 RS09220
gene id: 45243:CKV80_RS09220
uniprot id: A0A0X8JBU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS03535
gene id: 45243:CKV80_RS03535
uniprot id: A0A0X8JAC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

45243:CKV80 RS08740
gene id: 45243:CKV80_RS08740
uniprot id: A0A0X8JC09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

45243:CKV80 RS08810
gene id: 45243:CKV80_RS08810
uniprot id: A0A0X8JCL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

45243:CKV80 RS11110
gene id: 45243:CKV80_RS11110
uniprot id: A0A0X8JB71
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS05970
gene id: 45243:CKV80_RS05970
uniprot id: A0A125S2P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

45243:CKV80 RS08825
gene id: 45243:CKV80_RS08825
uniprot id: A0A0X8JCK9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

45243:CKV80 RS09175
gene id: 45243:CKV80_RS09175
uniprot id: A0A0X8JBV2
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

45243:CKV80 RS04770
gene id: 45243:CKV80_RS04770
uniprot id: A0A0X8JAA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

45243:CKV80 RS04885
gene id: 45243:CKV80_RS04885
uniprot id: A0A0X8J9G1
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS06930
gene id: 45243:CKV80_RS06930
uniprot id: A0A125S285
names: Similarity
messages: Belongs to the nitroreductase family.

45243:CKV80 RS10260
gene id: 45243:CKV80_RS10260
uniprot id: A0A0X8JBH1
names: Similarity
messages: Belongs to the RecJ family.

45243:CKV80 RS05375
gene id: 45243:CKV80_RS05375
uniprot id: A0A125S2V4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

45243:CKV80 RS11810
gene id: 45243:CKV80_RS11810
uniprot id: A0A125S3S6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

45243:CKV80 RS09290
gene id: 45243:CKV80_RS09290
uniprot id: A0A0X8JBT5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

45243:CKV80 RS08590
gene id: 45243:CKV80_RS08590
uniprot id: A0A0X8JC15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

45243:CKV80 RS09515
gene id: 45243:CKV80_RS09515
uniprot id: A0A0X8JBR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

45243:CKV80 RS09250
gene id: 45243:CKV80_RS09250
uniprot id: A0A125S472
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

45243:CKV80 RS10180
gene id: 45243:CKV80_RS10180
uniprot id: A0A125S420
names: Similarity
messages: Belongs to the universal stress protein A family.

45243:CKV80 RS02270
gene id: 45243:CKV80_RS02270
uniprot id: A0A0X8JC86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

45243:CKV80 RS11650
gene id: 45243:CKV80_RS11650
uniprot id: A0A0X8JBL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

45243:CKV80 RS01840
gene id: 45243:CKV80_RS01840
uniprot id: A0A125S3F8
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

45243:CKV80 RS07485
gene id: 45243:CKV80_RS07485
uniprot id: A0A125S1Y6
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS10425
gene id: 45243:CKV80_RS10425
uniprot id: A0A109W761
names: Similarity
messages: Belongs to the glutamine synthetase family.

45243:CKV80 RS04985
gene id: 45243:CKV80_RS04985
uniprot id: A0A125S2X8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

45243:CKV80 RS01220
gene id: 45243:CKV80_RS01220
uniprot id: A0A0X8JAH8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

45243:CKV80 RS05210
gene id: 45243:CKV80_RS05210
uniprot id: A0A125S2W5
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS10255
gene id: 45243:CKV80_RS10255
uniprot id: A0A0X8JBI0
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS05890
gene id: 45243:CKV80_RS05890
uniprot id: A0A125S2R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

45243:CKV80 RS00995
gene id: 45243:CKV80_RS00995
uniprot id: A0A125S3K8
names: Similarity
messages: Belongs to the peptidase S51 family.

45243:CKV80 RS08305
gene id: 45243:CKV80_RS08305
uniprot id: A0A125S1J3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

45243:CKV80 RS06365
gene id: 45243:CKV80_RS06365
uniprot id: A0A125S2I4
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS02920
gene id: 45243:CKV80_RS02920
uniprot id: A0A0X8J9T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

45243:CKV80 RS02930
gene id: 45243:CKV80_RS02930
uniprot id: A0A0X8JAV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

45243:CKV80 RS01915
gene id: 45243:CKV80_RS01915
uniprot id: A0A125S3F4
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

45243:CKV80 RS10635
gene id: 45243:CKV80_RS10635
uniprot id: A0A125S3Z2
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS02845
gene id: 45243:CKV80_RS02845
uniprot id: A0A0X8J9U9
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS05720
gene id: 45243:CKV80_RS05720
uniprot id: A0A125S2T5
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

45243:CKV80 RS09195
gene id: 45243:CKV80_RS09195
uniprot id: A0A0X8JCF0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

45243:CKV80 RS08885
gene id: 45243:CKV80_RS08885
uniprot id: A0A0X8JCK0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

45243:CKV80 RS04055
gene id: 45243:CKV80_RS04055
uniprot id: A0A0X8J9K5
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS11535
gene id: 45243:CKV80_RS11535
uniprot id: A0A125S3U1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

45243:CKV80 RS09855
gene id: 45243:CKV80_RS09855
uniprot id: A0A125S438
names: Similarity
messages: Belongs to the Skp family.

45243:CKV80 RS05450
gene id: 45243:CKV80_RS05450
uniprot id: A0A125S2V1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

45243:CKV80 RS11215
gene id: 45243:CKV80_RS11215
uniprot id: A0A125S3V8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

45243:CKV80 RS08750
gene id: 45243:CKV80_RS08750
uniprot id: A0A0X8JCV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

45243:CKV80 RS03315
gene id: 45243:CKV80_RS03315
uniprot id: A0A125S375
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

45243:CKV80 RS06240
gene id: 45243:CKV80_RS06240
uniprot id: A0A125S2K7
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS01275
gene id: 45243:CKV80_RS01275
uniprot id: A0A0X8JBC2
names: Subcellular Location Annotation
messages: chloroplast

45243:CKV80 RS05090
gene id: 45243:CKV80_RS05090
uniprot id: A0A0X8JA66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

45243:CKV80 RS09795
gene id: 45243:CKV80_RS09795
uniprot id: A0A0X8JCX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

45243:CKV80 RS08280
gene id: 45243:CKV80_RS08280
uniprot id: A0A125S1J7
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

45243:CKV80 RS06460
gene id: 45243:CKV80_RS06460
uniprot id: A0A125S2G8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS11785
gene id: 45243:CKV80_RS11785
uniprot id: A0A0X8JAY5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS10455
gene id: 45243:CKV80_RS10455
uniprot id: A0A0X8JC02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

45243:CKV80 RS01835
gene id: 45243:CKV80_RS01835
uniprot id: A0A125S3F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

45243:CKV80 RS04705
gene id: 45243:CKV80_RS04705
uniprot id: A0A0X8J9H0
names: Similarity
messages: Belongs to the UPF0246 family.

45243:CKV80 RS08680
gene id: 45243:CKV80_RS08680
uniprot id: A0A0X8JC00
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS03445
gene id: 45243:CKV80_RS03445
uniprot id: A0A0X8JAQ3
names: Similarity
messages: Belongs to the peptidase S1C family.

45243:CKV80 RS08875
gene id: 45243:CKV80_RS08875
uniprot id: A0A109W1S3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

45243:CKV80 RS05385
gene id: 45243:CKV80_RS05385
uniprot id: A0A0X8J9S4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

45243:CKV80 RS08215
gene id: 45243:CKV80_RS08215
uniprot id: A0A0X8JCN8
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS01865
gene id: 45243:CKV80_RS01865
uniprot id: A0A0X8JAW9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS02810
gene id: 45243:CKV80_RS02810
uniprot id: A0A0X8J9Z1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

45243:CKV80 RS09990
gene id: 45243:CKV80_RS09990
uniprot id: A0A0X8JBK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

45243:CKV80 RS08095
gene id: 45243:CKV80_RS08095
uniprot id: A0A125S1M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS08205
gene id: 45243:CKV80_RS08205
uniprot id: A0A125S1L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

45243:CKV80 RS07100
gene id: 45243:CKV80_RS07100
uniprot id: A0A125S256
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS11615
gene id: 45243:CKV80_RS11615
uniprot id: A0A125S3T6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

45243:CKV80 RS02115
gene id: 45243:CKV80_RS02115
uniprot id: A0A125S3E4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS06485
gene id: 45243:CKV80_RS06485
uniprot id: A0A125S2G3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

45243:CKV80 RS10060
gene id: 45243:CKV80_RS10060
uniprot id: A0A0X8JBI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS10715
gene id: 45243:CKV80_RS10715
uniprot id: A0A125S3Y9
names: Similarity
messages: Belongs to the CarB family.

45243:CKV80 RS00170
gene id: 45243:CKV80_RS00170
uniprot id: A0A125S3Q8
names: Similarity
messages: Belongs to the aldose epimerase family.

45243:CKV80 RS08645
gene id: 45243:CKV80_RS08645
uniprot id: A0A0X8JCM4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

45243:CKV80 RS10445
gene id: 45243:CKV80_RS10445
uniprot id: A0A125S403
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS10920
gene id: 45243:CKV80_RS10920
uniprot id: A0A0X8JBU9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

45243:CKV80 RS03520
gene id: 45243:CKV80_RS03520
uniprot id: A0A125S362
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

45243:CKV80 RS05045
gene id: 45243:CKV80_RS05045
uniprot id: A0A125S2X6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

45243:CKV80 RS10130
gene id: 45243:CKV80_RS10130
uniprot id: A0A0X8JBI8
names: Similarity
messages: Belongs to the DprA/Smf family.

45243:CKV80 RS08850
gene id: 45243:CKV80_RS08850
uniprot id: A0A0X8JBZ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

45243:CKV80 RS07630
gene id: 45243:CKV80_RS07630
uniprot id: A0A125S1W1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

45243:CKV80 RS07590
gene id: 45243:CKV80_RS07590
uniprot id: A0A125S1W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS04875
gene id: 45243:CKV80_RS04875
uniprot id: A0A0X8J9G4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

45243:CKV80 RS08620
gene id: 45243:CKV80_RS08620
uniprot id: A0A109W1T2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

45243:CKV80 RS07910
gene id: 45243:CKV80_RS07910
uniprot id: A0A125S1R2
names: Similarity
messages: Belongs to the nitroreductase family.

45243:CKV80 RS07875
gene id: 45243:CKV80_RS07875
uniprot id: A0A125S1R7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

45243:CKV80 RS04130
gene id: 45243:CKV80_RS04130
uniprot id: A0A0X8JAH6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS04365
gene id: 45243:CKV80_RS04365
uniprot id: A0A125S313
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

45243:CKV80 RS10685
gene id: 45243:CKV80_RS10685
uniprot id: A0A0X8JBD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

45243:CKV80 RS05360
gene id: 45243:CKV80_RS05360
uniprot id: A0A0X8J9D0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

45243:CKV80 RS04120
gene id: 45243:CKV80_RS04120
uniprot id: A0A0X8JAH5
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS09580
gene id: 45243:CKV80_RS09580
uniprot id: A0A0X8JCA9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS07835
gene id: 45243:CKV80_RS07835
uniprot id: A0A125S1S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

45243:CKV80 RS03040
gene id: 45243:CKV80_RS03040
uniprot id: A0A0X8J9W5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

45243:CKV80 RS11515
gene id: 45243:CKV80_RS11515
uniprot id: A0A0X8JB30
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS01780
gene id: 45243:CKV80_RS01780
uniprot id: A0A0X8JA63
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

45243:CKV80 RS10225
gene id: 45243:CKV80_RS10225
uniprot id: A0A0X8JCC1
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS06475
gene id: 45243:CKV80_RS06475
uniprot id: A0A125S2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

45243:CKV80 RS11610
gene id: 45243:CKV80_RS11610
uniprot id: A0A0X8JB12
names: Similarity
messages: Belongs to the NusB family.

45243:CKV80 RS04510
gene id: 45243:CKV80_RS04510
uniprot id: A0A125S305
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

45243:CKV80 RS03770
gene id: 45243:CKV80_RS03770
uniprot id: A0A0X8JA98
names: Similarity
messages: Belongs to the aspartokinase family.

45243:CKV80 RS04150
gene id: 45243:CKV80_RS04150
uniprot id: A0A0X8J9K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

45243:CKV80 RS09640
gene id: 45243:CKV80_RS09640
uniprot id: A0A0X8JCA8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

45243:CKV80 RS02795
gene id: 45243:CKV80_RS02795
uniprot id: A0A0X8J9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

45243:CKV80 RS00020
gene id: 45243:CKV80_RS00020
uniprot id: A0A0X8JBS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

45243:CKV80 RS10615
gene id: 45243:CKV80_RS10615
uniprot id: A0A125S3Z5
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS01470
gene id: 45243:CKV80_RS01470
uniprot id: A0A0X8JAD2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

45243:CKV80 RS10230
gene id: 45243:CKV80_RS10230
uniprot id: A0A0X8JC24
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS05475
gene id: 45243:CKV80_RS05475
uniprot id: A0A125S2U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS01665
gene id: 45243:CKV80_RS01665
uniprot id: A0A125S3H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

45243:CKV80 RS10585
gene id: 45243:CKV80_RS10585
uniprot id: A0A0X8JBY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

45243:CKV80 RS06080
gene id: 45243:CKV80_RS06080
uniprot id: A0A125S2M7
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS09890
gene id: 45243:CKV80_RS09890
uniprot id: A0A0X8JCB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

45243:CKV80 RS09605
gene id: 45243:CKV80_RS09605
uniprot id: A0A125S456
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

45243:CKV80 RS00395
gene id: 45243:CKV80_RS00395
uniprot id: A0A0X8JAR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

45243:CKV80 RS05365
gene id: 45243:CKV80_RS05365
uniprot id: A0A125S2V6
names: Similarity
messages: Belongs to the arginase family.

45243:CKV80 RS01140
gene id: 45243:CKV80_RS01140
uniprot id: A0A0X8JAG9
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS06575
gene id: 45243:CKV80_RS06575
uniprot id: A0A125S2E8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

45243:CKV80 RS08780
gene id: 45243:CKV80_RS08780
uniprot id: A0A0X8JCD5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

45243:CKV80 RS03665
gene id: 45243:CKV80_RS03665
uniprot id: A0A125S355
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

45243:CKV80 RS06275
gene id: 45243:CKV80_RS06275
uniprot id: A0A125S2K1
names: Similarity
messages: Belongs to the peptidase S9A family.

45243:CKV80 RS07580
gene id: 45243:CKV80_RS07580
uniprot id: A0A125S1W9
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

45243:CKV80 RS08960
gene id: 45243:CKV80_RS08960
uniprot id: A0A120KM72
names: Similarity
messages: Belongs to the Dps family.

45243:CKV80 RS05020
gene id: 45243:CKV80_RS05020
uniprot id: A0A0X8J9X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

45243:CKV80 RS09115
gene id: 45243:CKV80_RS09115
uniprot id: A0A0X8JBV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

45243:CKV80 RS01380
gene id: 45243:CKV80_RS01380
uniprot id: A0A0X8JB24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS09875
gene id: 45243:CKV80_RS09875
uniprot id: A0A0X8JC78
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

45243:CKV80 RS05205
gene id: 45243:CKV80_RS05205
uniprot id: A0A125S2W6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS03500
gene id: 45243:CKV80_RS03500
uniprot id: A0A125S365
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

45243:CKV80 RS08925
gene id: 45243:CKV80_RS08925
uniprot id: A0A0X8JBY4
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

45243:CKV80 RS09225
gene id: 45243:CKV80_RS09225
uniprot id: A0A125S476
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

45243:CKV80 RS03950
gene id: 45243:CKV80_RS03950
uniprot id: A0A0X8J9L8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS07710
gene id: 45243:CKV80_RS07710
uniprot id: A0A125S1U7
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS06970
gene id: 45243:CKV80_RS06970
uniprot id: A0A0X8JCR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS07220
gene id: 45243:CKV80_RS07220
uniprot id: A0A125S234
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS02835
gene id: 45243:CKV80_RS02835
uniprot id: A0A0X8JAL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS08760
gene id: 45243:CKV80_RS08760
uniprot id: A0A0X8JCK2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

45243:CKV80 RS04105
gene id: 45243:CKV80_RS04105
uniprot id: A0A0X8JA58
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

45243:CKV80 RS10520
gene id: 45243:CKV80_RS10520
uniprot id: A0A125S400
names: Similarity
messages: Belongs to the peptidase C1 family.

45243:CKV80 RS08730
gene id: 45243:CKV80_RS08730
uniprot id: A0A0X8JCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

45243:CKV80 RS09425
gene id: 45243:CKV80_RS09425
uniprot id: A0A125S464
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

45243:CKV80 RS01215
gene id: 45243:CKV80_RS01215
uniprot id: A0A0X8JAF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

45243:CKV80 RS11075
gene id: 45243:CKV80_RS11075
uniprot id: A0A0X8JBT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

45243:CKV80 RS00225
gene id: 45243:CKV80_RS00225
uniprot id: A0A0X8JAT0
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS02780
gene id: 45243:CKV80_RS02780
uniprot id: A0A0X8JAX6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

45243:CKV80 RS01425
gene id: 45243:CKV80_RS01425
uniprot id: A0A0X8JB34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

45243:CKV80 RS03260
gene id: 45243:CKV80_RS03260
uniprot id: A0A125S377
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

45243:CKV80 RS10750
gene id: 45243:CKV80_RS10750
uniprot id: A0A0X8JC57
names: Similarity
messages: Belongs to the peptidase C40 family.

45243:CKV80 RS08755
gene id: 45243:CKV80_RS08755
uniprot id: A0A0X8JCU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

45243:CKV80 RS03660
gene id: 45243:CKV80_RS03660
uniprot id: A0A125S356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS11000
gene id: 45243:CKV80_RS11000
uniprot id: A0A0X8JBU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

45243:CKV80 RS03235
gene id: 45243:CKV80_RS03235
uniprot id: A0A125S381
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

45243:CKV80 RS02110
gene id: 45243:CKV80_RS02110
uniprot id: A0A125S3E5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

45243:CKV80 RS02245
gene id: 45243:CKV80_RS02245
uniprot id: A0A0X8JAS7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

45243:CKV80 RS01815
gene id: 45243:CKV80_RS01815
uniprot id: A0A0X8JA93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

45243:CKV80 RS03590
gene id: 45243:CKV80_RS03590
uniprot id: A0A125S359
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

45243:CKV80 RS04550
gene id: 45243:CKV80_RS04550
uniprot id: A0A0X8JAD1
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS07945
gene id: 45243:CKV80_RS07945
uniprot id: A0A125S1Q6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

45243:CKV80 RS09960
gene id: 45243:CKV80_RS09960
uniprot id: A0A0X8JC68
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

45243:CKV80 RS06600
gene id: 45243:CKV80_RS06600
uniprot id: A0A125S2E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

45243:CKV80 RS10460
gene id: 45243:CKV80_RS10460
uniprot id: A0A125S402
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

45243:CKV80 RS09420
gene id: 45243:CKV80_RS09420
uniprot id: A0A125S465
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

45243:CKV80 RS07885
gene id: 45243:CKV80_RS07885
uniprot id: A0A125S1R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

45243:CKV80 RS03255
gene id: 45243:CKV80_RS03255
uniprot id: A0A0X8JAG4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

45243:CKV80 RS10440
gene id: 45243:CKV80_RS10440
uniprot id: A0A125S404
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS11690
gene id: 45243:CKV80_RS11690
uniprot id: A0A0X8JAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

45243:CKV80 RS11465
gene id: 45243:CKV80_RS11465
uniprot id: A0A125S3U4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

45243:CKV80 RS08910
gene id: 45243:CKV80_RS08910
uniprot id: A0A0X8JCS0
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

45243:CKV80 RS00315
gene id: 45243:CKV80_RS00315
uniprot id: A0A0X8JAU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

45243:CKV80 RS06120
gene id: 45243:CKV80_RS06120
uniprot id: A0A125S2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

45243:CKV80 RS01715
gene id: 45243:CKV80_RS01715
uniprot id: A0A0X8JAY6
names: Similarity
messages: Belongs to the YoeB family.

45243:CKV80 RS00715
gene id: 45243:CKV80_RS00715
uniprot id: A0A0X8JAN9
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS02075
gene id: 45243:CKV80_RS02075
uniprot id: A0A0X8JA75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

45243:CKV80 RS02125
gene id: 45243:CKV80_RS02125
uniprot id: A0A0X8JAU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

45243:CKV80 RS01885
gene id: 45243:CKV80_RS01885
uniprot id: A0A0X8JAX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS03890
gene id: 45243:CKV80_RS03890
uniprot id: A0A0X8JC66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

45243:CKV80 RS01245
gene id: 45243:CKV80_RS01245
uniprot id: A0A0X8JB50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

45243:CKV80 RS00345
gene id: 45243:CKV80_RS00345
uniprot id: A0A0X8JBF7
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

45243:CKV80 RS09865
gene id: 45243:CKV80_RS09865
uniprot id: A0A125S437
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

45243:CKV80 RS02120
gene id: 45243:CKV80_RS02120
uniprot id: A0A125S3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

45243:CKV80 RS05610
gene id: 45243:CKV80_RS05610
uniprot id: A0A0X8J9B9
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS08920
gene id: 45243:CKV80_RS08920
uniprot id: A0A0X8JBX0
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS10770
gene id: 45243:CKV80_RS10770
uniprot id: A0A0X8JBA2
names: Similarity
messages: Belongs to the HSP15 family.

45243:CKV80 RS10155
gene id: 45243:CKV80_RS10155
uniprot id: A0A0X8JBH8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

45243:CKV80 RS01860
gene id: 45243:CKV80_RS01860
uniprot id: A0A0X8JCV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS06230
gene id: 45243:CKV80_RS06230
uniprot id: A0A125S2K9
names: Similarity
messages: Belongs to the glycosyl hydrolase 66 family.

45243:CKV80 RS11820
gene id: 45243:CKV80_RS11820
uniprot id: A0A125S3S4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

45243:CKV80 RS10160
gene id: 45243:CKV80_RS10160
uniprot id: A0A0X8JBI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

45243:CKV80 RS06560
gene id: 45243:CKV80_RS06560
uniprot id: A0A125S2F1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

45243:CKV80 RS06220
gene id: 45243:CKV80_RS06220
uniprot id: A0A120KKT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

45243:CKV80 RS10560
gene id: 45243:CKV80_RS10560
uniprot id: A0A0X8JCX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

45243:CKV80 RS07380
gene id: 45243:CKV80_RS07380
uniprot id: A0A125S206
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

45243:CKV80 RS04945
gene id: 45243:CKV80_RS04945
uniprot id: A0A0X8J9Y2
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

45243:CKV80 RS01260
gene id: 45243:CKV80_RS01260
uniprot id: A0A0X8JAC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

45243:CKV80 RS00810
gene id: 45243:CKV80_RS00810
uniprot id: A0A0X8JAM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

45243:CKV80 RS09810
gene id: 45243:CKV80_RS09810
uniprot id: A0A0X8JCH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

45243:CKV80 RS06420
gene id: 45243:CKV80_RS06420
uniprot id: A0A125S2H4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

45243:CKV80 RS11895
gene id: 45243:CKV80_RS11895
uniprot id: A0A125S3R9
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS07645
gene id: 45243:CKV80_RS07645
uniprot id: A0A125S1V8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

45243:CKV80 RS10145
gene id: 45243:CKV80_RS10145
uniprot id: A0A0X8JCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

45243:CKV80 RS10430
gene id: 45243:CKV80_RS10430
uniprot id: A0A125S406
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

45243:CKV80 RS04215
gene id: 45243:CKV80_RS04215
uniprot id: A0A0X8JA60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

45243:CKV80 RS09525
gene id: 45243:CKV80_RS09525
uniprot id: A0A125S461
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

45243:CKV80 RS04285
gene id: 45243:CKV80_RS04285
uniprot id: A0A0X8J9H3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

45243:CKV80 RS09835
gene id: 45243:CKV80_RS09835
uniprot id: A0A0X8JBM5
names: Similarity
messages: Belongs to the asparaginase 1 family.

45243:CKV80 RS03625
gene id: 45243:CKV80_RS03625
uniprot id: A0A0X8JAN3
names: Subcellular Location Annotation
messages: Cytoplasm

45243:CKV80 RS05725
gene id: 45243:CKV80_RS05725
uniprot id: A0A125S2T4
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS04585
gene id: 45243:CKV80_RS04585
uniprot id: A0A0X8J9H5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

45243:CKV80 RS07620
gene id: 45243:CKV80_RS07620
uniprot id: A0A125S1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

45243:CKV80 RS02940
gene id: 45243:CKV80_RS02940
uniprot id: A0A0X8JAK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

45243:CKV80 RS07270
gene id: 45243:CKV80_RS07270
uniprot id: A0A125S225
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS10040
gene id: 45243:CKV80_RS10040
uniprot id: A0A0X8JC55
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

45243:CKV80 RS00940
gene id: 45243:CKV80_RS00940
uniprot id: A0A0X8JB83
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS11105
gene id: 45243:CKV80_RS11105
uniprot id: A0A0X8JB51
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

45243:CKV80 RS04810
gene id: 45243:CKV80_RS04810
uniprot id: A0A125S2Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

45243:CKV80 RS08905
gene id: 45243:CKV80_RS08905
uniprot id: A0A0X8JCT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

45243:CKV80 RS03205
gene id: 45243:CKV80_RS03205
uniprot id: A0A0X8JAI0
names: Similarity
messages: Belongs to the threonine synthase family.

45243:CKV80 RS01900
gene id: 45243:CKV80_RS01900
uniprot id: A0A0X8JA95
names: Similarity
messages: Belongs to the DEAD box helicase family.

45243:CKV80 RS00035
gene id: 45243:CKV80_RS00035
uniprot id: A0A0X8JAW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS11885
gene id: 45243:CKV80_RS11885
uniprot id: A0A125S3S1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

45243:CKV80 RS11010
gene id: 45243:CKV80_RS11010
uniprot id: A0A0X8JC18
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

45243:CKV80 RS07330
gene id: 45243:CKV80_RS07330
uniprot id: A0A125S214
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

45243:CKV80 RS04920
gene id: 45243:CKV80_RS04920
uniprot id: A0A109W1V1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

45243:CKV80 RS07510
gene id: 45243:CKV80_RS07510
uniprot id: A0A125S1Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS00755
gene id: 45243:CKV80_RS00755
uniprot id: A0A109W1W4
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS03905
gene id: 45243:CKV80_RS03905
uniprot id: A0A125S339
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

45243:CKV80 RS11560
gene id: 45243:CKV80_RS11560
uniprot id: A0A125S3T7
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

45243:CKV80 RS11395
gene id: 45243:CKV80_RS11395
uniprot id: A0A125S3U8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

45243:CKV80 RS05885
gene id: 45243:CKV80_RS05885
uniprot id: A0A125S2R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

45243:CKV80 RS02130
gene id: 45243:CKV80_RS02130
uniprot id: A0A125S3E2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

45243:CKV80 RS05515
gene id: 45243:CKV80_RS05515
uniprot id: A0A0X8JA16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

45243:CKV80 RS07995
gene id: 45243:CKV80_RS07995
uniprot id: A0A125S1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

45243:CKV80 RS03285
gene id: 45243:CKV80_RS03285
uniprot id: A0A0X8JAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

45243:CKV80 RS01480
gene id: 45243:CKV80_RS01480
uniprot id: A0A0X8JC89
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

45243:CKV80 RS08275
gene id: 45243:CKV80_RS08275
uniprot id: A0A0X8JC29
names: Similarity
messages: Belongs to the peptidase S8 family.

45243:CKV80 RS10480
gene id: 45243:CKV80_RS10480
uniprot id: A0A0X8JC90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

45243:CKV80 RS07295
gene id: 45243:CKV80_RS07295
uniprot id: A0A125S220
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS08735
gene id: 45243:CKV80_RS08735
uniprot id: A0A120KKR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

45243:CKV80 RS08915
gene id: 45243:CKV80_RS08915
uniprot id: A0A0X8JCI2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS07690
gene id: 45243:CKV80_RS07690
uniprot id: A0A125S1V0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS00700
gene id: 45243:CKV80_RS00700
uniprot id: A0A0X8JBJ9
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS11385
gene id: 45243:CKV80_RS11385
uniprot id: A0A125S3V0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

45243:CKV80 RS08415
gene id: 45243:CKV80_RS08415
uniprot id: A0A125S1H3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

45243:CKV80 RS05100
gene id: 45243:CKV80_RS05100
uniprot id: A0A0X8J9E8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

45243:CKV80 RS06370
gene id: 45243:CKV80_RS06370
uniprot id: A0A125S2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

45243:CKV80 RS07110
gene id: 45243:CKV80_RS07110
uniprot id: A0A125S254
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

45243:CKV80 RS02815
gene id: 45243:CKV80_RS02815
uniprot id: A0A125S3A6
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS02725
gene id: 45243:CKV80_RS02725
uniprot id: A0A125S3B0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

45243:CKV80 RS04690
gene id: 45243:CKV80_RS04690
uniprot id: A0A0X8J9H4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

45243:CKV80 RS05935
gene id: 45243:CKV80_RS05935
uniprot id: A0A125S2Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

45243:CKV80 RS00885
gene id: 45243:CKV80_RS00885
uniprot id: A0A0X8JAL6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

45243:CKV80 RS11265
gene id: 45243:CKV80_RS11265
uniprot id: A0A0X8JB58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

45243:CKV80 RS06050
gene id: 45243:CKV80_RS06050
uniprot id: A0A125S2N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

45243:CKV80 RS06515
gene id: 45243:CKV80_RS06515
uniprot id: A0A125S2F8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS04255
gene id: 45243:CKV80_RS04255
uniprot id: A0A125S319
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

45243:CKV80 RS04820
gene id: 45243:CKV80_RS04820
uniprot id: A0A125S2Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

45243:CKV80 RS06335
gene id: 45243:CKV80_RS06335
uniprot id: A0A125S2J0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS10825
gene id: 45243:CKV80_RS10825
uniprot id: A0A0X8JBW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

45243:CKV80 RS08695
gene id: 45243:CKV80_RS08695
uniprot id: A0A0X8JC12
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

45243:CKV80 RS07760
gene id: 45243:CKV80_RS07760
uniprot id: A0A125S1T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

45243:CKV80 RS11485
gene id: 45243:CKV80_RS11485
uniprot id: A0A0X8JAZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

45243:CKV80 RS09040
gene id: 45243:CKV80_RS09040
uniprot id: A0A120KKR8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

45243:CKV80 RS11435
gene id: 45243:CKV80_RS11435
uniprot id: A0A0X8JB36
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

45243:CKV80 RS00815
gene id: 45243:CKV80_RS00815
uniprot id: A0A0X8JAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

45243:CKV80 RS02805
gene id: 45243:CKV80_RS02805
uniprot id: A0A0X8J9Y5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

45243:CKV80 RS02145
gene id: 45243:CKV80_RS02145
uniprot id: A0A0X8JAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

45243:CKV80 RS06565
gene id: 45243:CKV80_RS06565
uniprot id: A0A125S2F0
names: Similarity
messages: Belongs to the pyruvate kinase family.

45243:CKV80 RS02020
gene id: 45243:CKV80_RS02020
uniprot id: A0A125S3E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

45243:CKV80 RS03270
gene id: 45243:CKV80_RS03270
uniprot id: A0A0X8JAG0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS01800
gene id: 45243:CKV80_RS01800
uniprot id: A0A0X8JAY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

45243:CKV80 RS01225
gene id: 45243:CKV80_RS01225
uniprot id: A0A125S3J6
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

45243:CKV80 RS05405
gene id: 45243:CKV80_RS05405
uniprot id: A0A0X8JA33
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS08360
gene id: 45243:CKV80_RS08360
uniprot id: A0A125S1I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

45243:CKV80 RS05655
gene id: 45243:CKV80_RS05655
uniprot id: A0A0X8J987
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS05670
gene id: 45243:CKV80_RS05670
uniprot id: A0A0X8J9Z6
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS06595
gene id: 45243:CKV80_RS06595
uniprot id: A0A125S2E5
names: Similarity
messages: Belongs to the YoeB family.

45243:CKV80 RS07085
gene id: 45243:CKV80_RS07085
uniprot id: A0A125S260
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS03945
gene id: 45243:CKV80_RS03945
uniprot id: A0A0X8JA89
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS10235
gene id: 45243:CKV80_RS10235
uniprot id: A0A0X8JBG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS08160
gene id: 45243:CKV80_RS08160
uniprot id: A0A125S1L7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

45243:CKV80 RS03145
gene id: 45243:CKV80_RS03145
uniprot id: A0A0X8J9V5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

45243:CKV80 RS00765
gene id: 45243:CKV80_RS00765
uniprot id: A0A125S3M2
names: Similarity
messages: Belongs to the peptidase M16 family.

45243:CKV80 RS00130
gene id: 45243:CKV80_RS00130
uniprot id: A0A0X8JAV0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

45243:CKV80 RS05995
gene id: 45243:CKV80_RS05995
uniprot id: A0A125S2P3
names: Similarity
messages: Belongs to the nitroreductase family.

45243:CKV80 RS05490
gene id: 45243:CKV80_RS05490
uniprot id: A0A109W751
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

45243:CKV80 RS06545
gene id: 45243:CKV80_RS06545
uniprot id: A0A125S2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

45243:CKV80 RS05750
gene id: 45243:CKV80_RS05750
uniprot id: A0A125S2T1
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

45243:CKV80 RS00340
gene id: 45243:CKV80_RS00340
uniprot id: A0A125S3P8
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

45243:CKV80 RS06305
gene id: 45243:CKV80_RS06305
uniprot id: A0A125S2J6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS07055
gene id: 45243:CKV80_RS07055
uniprot id: A0A125S266
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

45243:CKV80 RS00350
gene id: 45243:CKV80_RS00350
uniprot id: A0A125S3P7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

45243:CKV80 RS04995
gene id: 45243:CKV80_RS04995
uniprot id: A0A125S2X7
names: Similarity
messages: Belongs to the IMPACT family.

45243:CKV80 RS07525
gene id: 45243:CKV80_RS07525
uniprot id: A0A125S1X9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

45243:CKV80 RS07825
gene id: 45243:CKV80_RS07825
uniprot id: A0A125S1S5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS05705
gene id: 45243:CKV80_RS05705
uniprot id: A0A120KKS6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

45243:CKV80 RS07605
gene id: 45243:CKV80_RS07605
uniprot id: A0A125S1W4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

45243:CKV80 RS10760
gene id: 45243:CKV80_RS10760
uniprot id: A0A0X8JBB5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

45243:CKV80 RS04420
gene id: 45243:CKV80_RS04420
uniprot id: A0A0X8J9I6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

45243:CKV80 RS06640
gene id: 45243:CKV80_RS06640
uniprot id: A0A125S2D6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

45243:CKV80 RS01970
gene id: 45243:CKV80_RS01970
uniprot id: A0A0X8JA80
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

45243:CKV80 RS07635
gene id: 45243:CKV80_RS07635
uniprot id: A0A125S1W0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

45243:CKV80 RS09975
gene id: 45243:CKV80_RS09975
uniprot id: A0A0X8JCF1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

45243:CKV80 RS03980
gene id: 45243:CKV80_RS03980
uniprot id: A0A0X8JC69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

45243:CKV80 RS00875
gene id: 45243:CKV80_RS00875
uniprot id: A0A0X8JBG3
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS05185
gene id: 45243:CKV80_RS05185
uniprot id: A0A0X8J9E2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

45243:CKV80 RS05650
gene id: 45243:CKV80_RS05650
uniprot id: A0A125S2T7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

45243:CKV80 RS04070
gene id: 45243:CKV80_RS04070
uniprot id: A0A125S330
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

45243:CKV80 RS10840
gene id: 45243:CKV80_RS10840
uniprot id: A0A0X8JC39
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

45243:CKV80 RS00555
gene id: 45243:CKV80_RS00555
uniprot id: A0A0X8JBC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

45243:CKV80 RS11085
gene id: 45243:CKV80_RS11085
uniprot id: A0A0X8JC07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

45243:CKV80 RS06840
gene id: 45243:CKV80_RS06840
uniprot id: A0A125S299
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

45243:CKV80 RS07300
gene id: 45243:CKV80_RS07300
uniprot id: A0A125S219
names: Similarity
messages: Belongs to the SusD family.

45243:CKV80 RS00835
gene id: 45243:CKV80_RS00835
uniprot id: A0A125S3M0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

45243:CKV80 RS07400
gene id: 45243:CKV80_RS07400
uniprot id: A0A125S202
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

45243:CKV80 RS08725
gene id: 45243:CKV80_RS08725
uniprot id: A0A109W739
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

45243:CKV80 RS07755
gene id: 45243:CKV80_RS07755
uniprot id: A0A125S1T8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS05915
gene id: 45243:CKV80_RS05915
uniprot id: A0A125S2Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

45243:CKV80 RS00110
gene id: 45243:CKV80_RS00110
uniprot id: A0A0X8JBQ6
names: Similarity
messages: Belongs to the BshC family.

45243:CKV80 RS08130
gene id: 45243:CKV80_RS08130
uniprot id: A0A125S1M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

45243:CKV80 RS11285
gene id: 45243:CKV80_RS11285
uniprot id: A0A125S3V6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

45243:CKV80 RS09715
gene id: 45243:CKV80_RS09715
uniprot id: A0A0X8JC99
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

45243:CKV80 RS04180
gene id: 45243:CKV80_RS04180
uniprot id: A0A109W1V5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

45243:CKV80 RS04845
gene id: 45243:CKV80_RS04845
uniprot id: A0A0X8JAA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

45243:CKV80 RS11800
gene id: 45243:CKV80_RS11800
uniprot id: A0A0X8JC92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

45243:CKV80 RS01475
gene id: 45243:CKV80_RS01475
uniprot id: A0A0X8JAE3
names: Similarity
messages: Belongs to the peptidase S41A family.

45243:CKV80 RS10175
gene id: 45243:CKV80_RS10175
uniprot id: A0A125S421
names: Cofactor
messages: Binds 1 zinc ion per subunit.

45243:CKV80 RS00055
gene id: 45243:CKV80_RS00055
uniprot id: A0A0X8JCB2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

45243:CKV80 RS10950
gene id: 45243:CKV80_RS10950
uniprot id: A0A125S3X6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

45243:CKV80 RS03925
gene id: 45243:CKV80_RS03925
uniprot id: A0A0X8J9J3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

45243:CKV80 RS06690
gene id: 45243:CKV80_RS06690
uniprot id: A0A125S2C6
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS00830
gene id: 45243:CKV80_RS00830
uniprot id: A0A125S3M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

45243:CKV80 RS03360
gene id: 45243:CKV80_RS03360
uniprot id: A0A0X8JCT1
names: Similarity
messages: Belongs to the YciI family.

45243:CKV80 RS11905
gene id: 45243:CKV80_RS11905
uniprot id: A0A0X8JBJ3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

45243:CKV80 RS01280
gene id: 45243:CKV80_RS01280
uniprot id: A0A0X8JBC0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

45243:CKV80 RS02820
gene id: 45243:CKV80_RS02820
uniprot id: A0A125S3A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

45243:CKV80 RS01255
gene id: 45243:CKV80_RS01255
uniprot id: A0A0X8JD40
names: Similarity
messages: Belongs to the CapA family.

45243:CKV80 RS09930
gene id: 45243:CKV80_RS09930
uniprot id: A0A125S435
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

45243:CKV80 RS10605
gene id: 45243:CKV80_RS10605
uniprot id: A0A0X8JBD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

45243:CKV80 RS01200
gene id: 45243:CKV80_RS01200
uniprot id: A0A0X8JB35
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

45243:CKV80 RS03545
gene id: 45243:CKV80_RS03545
uniprot id: A0A0X8JAQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

45243:CKV80 RS02695
gene id: 45243:CKV80_RS02695
uniprot id: A0A0X8JA00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

45243:CKV80 RS11815
gene id: 45243:CKV80_RS11815
uniprot id: A0A125S3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

45243:CKV80 RS09850
gene id: 45243:CKV80_RS09850
uniprot id: A0A125S439
names: Similarity
messages: Belongs to the Skp family.

45243:CKV80 RS07860
gene id: 45243:CKV80_RS07860
uniprot id: A0A125S1S0
names: Similarity
messages: Belongs to the sigma-54 factor family.

45243:CKV80 RS00165
gene id: 45243:CKV80_RS00165
uniprot id: A0A125S3Q9
names: Similarity
messages: Belongs to the AIR synthase family.

45243:CKV80 RS09685
gene id: 45243:CKV80_RS09685
uniprot id: A0A125S450
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS03485
gene id: 45243:CKV80_RS03485
uniprot id: A0A0X8J9R3
names: Similarity
messages: Belongs to the DinB family.

45243:CKV80 RS05355
gene id: 45243:CKV80_RS05355
uniprot id: A0A0X8J9D3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

45243:CKV80 RS05755
gene id: 45243:CKV80_RS05755
uniprot id: A0A0X8JD10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS02105
gene id: 45243:CKV80_RS02105
uniprot id: A0A125S3E6
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS03675
gene id: 45243:CKV80_RS03675
uniprot id: A0A125S353
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

45243:CKV80 RS00710
gene id: 45243:CKV80_RS00710
uniprot id: A0A0X8JBA6
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

45243:CKV80 RS02155
gene id: 45243:CKV80_RS02155
uniprot id: A0A0X8JB32
names: Similarity
messages: Belongs to the fabD family.

45243:CKV80 RS10855
gene id: 45243:CKV80_RS10855
uniprot id: A0A0X8JBA7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

45243:CKV80 RS01190
gene id: 45243:CKV80_RS01190
uniprot id: A0A0X8JBD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

45243:CKV80 RS04005
gene id: 45243:CKV80_RS04005
uniprot id: A0A125S332
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

45243:CKV80 RS03490
gene id: 45243:CKV80_RS03490
uniprot id: A0A0X8J9R5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

45243:CKV80 RS02975
gene id: 45243:CKV80_RS02975
uniprot id: A0A125S394
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

45243:CKV80 RS06095
gene id: 45243:CKV80_RS06095
uniprot id: A0A125S2M4
names: Similarity
messages: Belongs to the NAD synthetase family.

45243:CKV80 RS06030
gene id: 45243:CKV80_RS06030
uniprot id: A0A125S2N7
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

45243:CKV80 RS03355
gene id: 45243:CKV80_RS03355
uniprot id: A0A0X8JAF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

45243:CKV80 RS11345
gene id: 45243:CKV80_RS11345
uniprot id: A0A0X8JBX9
names: Similarity
messages: Belongs to the YicC/YloC family.

45243:CKV80 RS10165
gene id: 45243:CKV80_RS10165
uniprot id: A0A0X8JBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

45243:CKV80 RS10535
gene id: 45243:CKV80_RS10535
uniprot id: A0A125S3Z8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

45243:CKV80 RS04065
gene id: 45243:CKV80_RS04065
uniprot id: A0A125S331
names: Similarity
messages: Belongs to the hemerythrin family.

45243:CKV80 RS08370
gene id: 45243:CKV80_RS08370
uniprot id: A0A125S1I2
names: Subcellular Location Annotation
messages: Membrane

45243:CKV80 RS08745
gene id: 45243:CKV80_RS08745
uniprot id: A0A0X8JCL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

45243:CKV80 RS10250
gene id: 45243:CKV80_RS10250
uniprot id: A0A0X8JBH9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

45243:CKV80 RS04560
gene id: 45243:CKV80_RS04560
uniprot id: A0A0X8JA18
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.