450851:PHZ RS13555
gene id: 450851:PHZ_RS13555
uniprot id: B4RGE4
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS03155
gene id: 450851:PHZ_RS03155
uniprot id: B4RF11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

450851:PHZ RS07255
gene id: 450851:PHZ_RS07255
uniprot id: B4R961
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

450851:PHZ RS08010
gene id: 450851:PHZ_RS08010
uniprot id: B4R9V5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

450851:PHZ RS03300
gene id: 450851:PHZ_RS03300
uniprot id: B4RF38
names: Similarity
messages: Belongs to the asparagine synthetase family.

450851:PHZ RS10925
gene id: 450851:PHZ_RS10925
uniprot id: B4RDL1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS12875
gene id: 450851:PHZ_RS12875
uniprot id: B4RFS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

450851:PHZ RS03330
gene id: 450851:PHZ_RS03330
uniprot id: B4RF43
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 copper ion per subunit.
messages: Periplasm

450851:PHZ RS10365
gene id: 450851:PHZ_RS10365
uniprot id: B4RCV7
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

450851:PHZ RS07875
gene id: 450851:PHZ_RS07875
uniprot id: B4R9T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

450851:PHZ RS08445
gene id: 450851:PHZ_RS08445
uniprot id: B4RAD5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

450851:PHZ RS18300
gene id: 450851:PHZ_RS18300
uniprot id: B4RB70
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS11720
gene id: 450851:PHZ_RS11720
uniprot id: B4REL8
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS14850
gene id: 450851:PHZ_RS14850
uniprot id: B4RHP6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS13450
gene id: 450851:PHZ_RS13450
uniprot id: B4RG16
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

450851:PHZ RS12770
gene id: 450851:PHZ_RS12770
uniprot id: B4RFE7
names: Similarity
messages: Belongs to the peptidase M24B family.

450851:PHZ RS02355
gene id: 450851:PHZ_RS02355
uniprot id: B4REA8
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

450851:PHZ RS14030
gene id: 450851:PHZ_RS14030
uniprot id: B4RGN9
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

450851:PHZ RS13620
gene id: 450851:PHZ_RS13620
uniprot id: B4RGF7
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS17265
gene id: 450851:PHZ_RS17265
uniprot id: B4RA17
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

450851:PHZ RS00125
gene id: 450851:PHZ_RS00125
uniprot id: B4RBH6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

450851:PHZ RS14025
gene id: 450851:PHZ_RS14025
uniprot id: B4RGN8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS17830
gene id: 450851:PHZ_RS17830
uniprot id: B4RAM9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

450851:PHZ RS18730
gene id: 450851:PHZ_RS18730
uniprot id: B4RBE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

450851:PHZ RS04445
gene id: 450851:PHZ_RS04445
uniprot id: B4RGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS00480
gene id: 450851:PHZ_RS00480
uniprot id: B4RBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS00010
gene id: 450851:PHZ_RS00010
uniprot id: B4RBF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

450851:PHZ RS00570
gene id: 450851:PHZ_RS00570
uniprot id: B4RCC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

450851:PHZ RS06090
gene id: 450851:PHZ_RS06090
uniprot id: B4R7Y9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS10190
gene id: 450851:PHZ_RS10190
uniprot id: B4RCS4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

450851:PHZ RS06835
gene id: 450851:PHZ_RS06835
uniprot id: B4R8M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

450851:PHZ RS20315
gene id: 450851:PHZ_RS20315
uniprot id: B4RIA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

450851:PHZ RS21875
gene id: 450851:PHZ_RS21875
uniprot id: B4R9E5
names: Similarity
messages: Belongs to the peptidase A24 family.

450851:PHZ RS04000
gene id: 450851:PHZ_RS04000
uniprot id: B4RFR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

450851:PHZ RS19085
gene id: 450851:PHZ_RS19085
uniprot id: B4RC68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

450851:PHZ RS04290
gene id: 450851:PHZ_RS04290
uniprot id: B4RG78
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

450851:PHZ RS19230
gene id: 450851:PHZ_RS19230
uniprot id: B4RC96
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

450851:PHZ RS20410
gene id: 450851:PHZ_RS20410
uniprot id: B4RIC5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

450851:PHZ RS09470
gene id: 450851:PHZ_RS09470
uniprot id: B4RBT1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

450851:PHZ RS10865
gene id: 450851:PHZ_RS10865
uniprot id: B4RDJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS07360
gene id: 450851:PHZ_RS07360
uniprot id: B4R980
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

450851:PHZ RS03650
gene id: 450851:PHZ_RS03650
uniprot id: B4RFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS11170
gene id: 450851:PHZ_RS11170
uniprot id: B4RE14
names: Similarity
messages: Belongs to the GST superfamily.

450851:PHZ RS02495
gene id: 450851:PHZ_RS02495
uniprot id: B4RED2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

450851:PHZ RS10095
gene id: 450851:PHZ_RS10095
uniprot id: B4RCQ5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

450851:PHZ RS00760
gene id: 450851:PHZ_RS00760
uniprot id: B4RCF6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

450851:PHZ RS04805
gene id: 450851:PHZ_RS04805
uniprot id: B4RGS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

450851:PHZ RS18825
gene id: 450851:PHZ_RS18825
uniprot id: B4RC17
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

450851:PHZ RS01785
gene id: 450851:PHZ_RS01785
uniprot id: B4RDP0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

450851:PHZ RS11020
gene id: 450851:PHZ_RS11020
uniprot id: B4RDY5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

450851:PHZ RS13180
gene id: 450851:PHZ_RS13180
uniprot id: B4RFX8
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

450851:PHZ RS06265
gene id: 450851:PHZ_RS06265
uniprot id: B4R816
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

450851:PHZ RS14435
gene id: 450851:PHZ_RS14435
uniprot id: B4RH70
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

450851:PHZ RS16240
gene id: 450851:PHZ_RS16240
uniprot id: B4R8W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS00645
gene id: 450851:PHZ_RS00645
uniprot id: B4RCD5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

450851:PHZ RS20500
gene id: 450851:PHZ_RS20500
uniprot id: B4RIE2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

450851:PHZ RS06155
gene id: 450851:PHZ_RS06155
uniprot id: B4R7Z6
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

450851:PHZ RS06840
gene id: 450851:PHZ_RS06840
uniprot id: B4R8M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

450851:PHZ RS05085
gene id: 450851:PHZ_RS05085
uniprot id: B4RGY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

450851:PHZ RS01965
gene id: 450851:PHZ_RS01965
uniprot id: B4RDS3
names: Similarity
messages: Belongs to the peptidase M17 family.

450851:PHZ RS19035
gene id: 450851:PHZ_RS19035
uniprot id: B4RC58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

450851:PHZ RS20100
gene id: 450851:PHZ_RS20100
uniprot id: B4RI68
names: Similarity
messages: Belongs to the Dps family.

450851:PHZ RS01650
gene id: 450851:PHZ_RS01650
uniprot id: B4RDB1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

450851:PHZ RS09525
gene id: 450851:PHZ_RS09525
uniprot id: B4RBU1
names: Function
messages: Acts on leucine, isoleucine and valine.

450851:PHZ RS13405
gene id: 450851:PHZ_RS13405
uniprot id: B4RG11
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

450851:PHZ RS18935
gene id: 450851:PHZ_RS18935
uniprot id: B4RC38
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

450851:PHZ RS17130
gene id: 450851:PHZ_RS17130
uniprot id: B4R9Z2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

450851:PHZ RS21110
gene id: 450851:PHZ_RS21110
uniprot id: B4RIQ3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

450851:PHZ RS09900
gene id: 450851:PHZ_RS09900
uniprot id: B4RCM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

450851:PHZ RS02215
gene id: 450851:PHZ_RS02215
uniprot id: B4RDX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

450851:PHZ RS01755
gene id: 450851:PHZ_RS01755
uniprot id: B4RDN4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

450851:PHZ RS00665
gene id: 450851:PHZ_RS00665
uniprot id: B4RCD8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS18110
gene id: 450851:PHZ_RS18110
uniprot id: B4RAS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

450851:PHZ RS16895
gene id: 450851:PHZ_RS16895
uniprot id: B4R9J8
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

450851:PHZ RS05270
gene id: 450851:PHZ_RS05270
uniprot id: B4RHC0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS12320
gene id: 450851:PHZ_RS12320
uniprot id: B4RF68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

450851:PHZ RS05935
gene id: 450851:PHZ_RS05935
uniprot id: B4R7W2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

450851:PHZ RS06000
gene id: 450851:PHZ_RS06000
uniprot id: B4R7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS09755
gene id: 450851:PHZ_RS09755
uniprot id: B4RBY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

450851:PHZ RS08975
gene id: 450851:PHZ_RS08975
uniprot id: B4RAY7
names: Similarity
messages: Belongs to the CFA/CMAS family.

450851:PHZ RS09090
gene id: 450851:PHZ_RS09090
uniprot id: B4RB06
names: Subcellular Location Annotation
messages: Cytoplasm

450851:PHZ RS01380
gene id: 450851:PHZ_RS01380
uniprot id: B4RD59
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

450851:PHZ RS09590
gene id: 450851:PHZ_RS09590
uniprot id: B4RBV4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

450851:PHZ RS06740
gene id: 450851:PHZ_RS06740
uniprot id: B4R8K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

450851:PHZ RS02965
gene id: 450851:PHZ_RS02965
uniprot id: B4REX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

450851:PHZ RS00120
gene id: 450851:PHZ_RS00120
uniprot id: B4RBH5
names: Similarity
messages: Belongs to the UPF0434 family.

450851:PHZ RS16650
gene id: 450851:PHZ_RS16650
uniprot id: B4R9F1
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS10815
gene id: 450851:PHZ_RS10815
uniprot id: B4RDI9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

450851:PHZ RS21225
gene id: 450851:PHZ_RS21225
uniprot id: B4RIS2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

450851:PHZ RS03975
gene id: 450851:PHZ_RS03975
uniprot id: B4RFR3
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS09595
gene id: 450851:PHZ_RS09595
uniprot id: B4RBV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

450851:PHZ RS19185
gene id: 450851:PHZ_RS19185
uniprot id: B4RC87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

450851:PHZ RS18185
gene id: 450851:PHZ_RS18185
uniprot id: B4RB47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

450851:PHZ RS07625
gene id: 450851:PHZ_RS07625
uniprot id: B4R9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: In C.crescentus, the flagellar filament is composed of multiple flagellins of 29 kDa; 27 kDa and 25 kDa.
messages: Secreted

450851:PHZ RS19270
gene id: 450851:PHZ_RS19270
uniprot id: B4RCA4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

450851:PHZ RS19890
gene id: 450851:PHZ_RS19890
uniprot id: B4RI31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS21220
gene id: 450851:PHZ_RS21220
uniprot id: B4RIS1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

450851:PHZ RS12985
gene id: 450851:PHZ_RS12985
uniprot id: B4RFU4
names: Similarity
messages: Belongs to the virb1 family.

450851:PHZ RS07150
gene id: 450851:PHZ_RS07150
uniprot id: B4R940
names: Similarity
messages: Belongs to the peptidase S11 family.

450851:PHZ RS14425
gene id: 450851:PHZ_RS14425
uniprot id: B4RH68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

450851:PHZ RS06855
gene id: 450851:PHZ_RS06855
uniprot id: B4R8M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

450851:PHZ RS02020
gene id: 450851:PHZ_RS02020
uniprot id: B4RDT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

450851:PHZ RS12590
gene id: 450851:PHZ_RS12590
uniprot id: B4RFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS05305
gene id: 450851:PHZ_RS05305
uniprot id: B4RHC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

450851:PHZ RS21350
gene id: 450851:PHZ_RS21350
uniprot id: B4RIU1
names: Similarity
messages: Belongs to the ParB family.

450851:PHZ RS19030
gene id: 450851:PHZ_RS19030
uniprot id: B4RC57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

450851:PHZ RS03175
gene id: 450851:PHZ_RS03175
uniprot id: B4RF15
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

450851:PHZ RS13840
gene id: 450851:PHZ_RS13840
uniprot id: B4RGK1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS20775
gene id: 450851:PHZ_RS20775
uniprot id: B4RIJ2
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS05080
gene id: 450851:PHZ_RS05080
uniprot id: B4RGX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

450851:PHZ RS11025
gene id: 450851:PHZ_RS11025
uniprot id: B4RDY6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS15170
gene id: 450851:PHZ_RS15170
uniprot id: B4RHV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS19925
gene id: 450851:PHZ_RS19925
uniprot id: B4RI37
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

450851:PHZ RS15775
gene id: 450851:PHZ_RS15775
uniprot id: B4R8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

450851:PHZ RS12835
gene id: 450851:PHZ_RS12835
uniprot id: B4RFF9
names: Similarity
messages: Belongs to the thioesterase PaaI family.

450851:PHZ RS17875
gene id: 450851:PHZ_RS17875
uniprot id: B4RAN8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

450851:PHZ RS20160
gene id: 450851:PHZ_RS20160
uniprot id: B4RI77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

450851:PHZ RS00795
gene id: 450851:PHZ_RS00795
uniprot id: B4RCG2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

450851:PHZ RS06900
gene id: 450851:PHZ_RS06900
uniprot id: B4R8N5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

450851:PHZ RS00865
gene id: 450851:PHZ_RS00865
uniprot id: B4RCH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

450851:PHZ RS18225
gene id: 450851:PHZ_RS18225
uniprot id: B4RB55
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS17695
gene id: 450851:PHZ_RS17695
uniprot id: B4RAK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

450851:PHZ RS07110
gene id: 450851:PHZ_RS07110
uniprot id: B4R932
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS20765
gene id: 450851:PHZ_RS20765
uniprot id: B4RIJ1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

450851:PHZ RS18370
gene id: 450851:PHZ_RS18370
uniprot id: B4RB84
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

450851:PHZ RS04620
gene id: 450851:PHZ_RS04620
uniprot id: B4RGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

450851:PHZ RS20025
gene id: 450851:PHZ_RS20025
uniprot id: B4RI54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS11750
gene id: 450851:PHZ_RS11750
uniprot id: B4REM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS17415
gene id: 450851:PHZ_RS17415
uniprot id: B4RA46
names: Similarity
messages: Belongs to the YkuD family.

450851:PHZ RS05300
gene id: 450851:PHZ_RS05300
uniprot id: B4RHC6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

450851:PHZ RS08760
gene id: 450851:PHZ_RS08760
uniprot id: B4RAV0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

450851:PHZ RS12920
gene id: 450851:PHZ_RS12920
uniprot id: B4RFT3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS12175
gene id: 450851:PHZ_RS12175
uniprot id: B4REU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

450851:PHZ RS20360
gene id: 450851:PHZ_RS20360
uniprot id: B4RIB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

450851:PHZ RS09585
gene id: 450851:PHZ_RS09585
uniprot id: B4RBV3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

450851:PHZ RS06050
gene id: 450851:PHZ_RS06050
uniprot id: B4R7Y4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

450851:PHZ RS04130
gene id: 450851:PHZ_RS04130
uniprot id: B4RG50
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

450851:PHZ RS09460
gene id: 450851:PHZ_RS09460
uniprot id: B4RBS9
names: Similarity
messages: Belongs to the HesB/IscA family.

450851:PHZ RS09790
gene id: 450851:PHZ_RS09790
uniprot id: B4RBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

450851:PHZ RS10320
gene id: 450851:PHZ_RS10320
uniprot id: B4RCU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

450851:PHZ RS15855
gene id: 450851:PHZ_RS15855
uniprot id: B4R8Q4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

450851:PHZ RS15040
gene id: 450851:PHZ_RS15040
uniprot id: B4RHT2
names: Similarity
messages: Belongs to the SufE family.

450851:PHZ RS12050
gene id: 450851:PHZ_RS12050
uniprot id: B4RES7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

450851:PHZ RS10185
gene id: 450851:PHZ_RS10185
uniprot id: B4RCS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

450851:PHZ RS00015
gene id: 450851:PHZ_RS00015
uniprot id: B4RBF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

450851:PHZ RS10195
gene id: 450851:PHZ_RS10195
uniprot id: B4RCS5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

450851:PHZ RS08420
gene id: 450851:PHZ_RS08420
uniprot id: B4RAD1
names: Similarity
messages: Belongs to the ArsC family.

450851:PHZ RS19200
gene id: 450851:PHZ_RS19200
uniprot id: B4RC90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

450851:PHZ RS02890
gene id: 450851:PHZ_RS02890
uniprot id: B4REW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

450851:PHZ RS10620
gene id: 450851:PHZ_RS10620
uniprot id: B4RDF2
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

450851:PHZ RS13075
gene id: 450851:PHZ_RS13075
uniprot id: B4RFW0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

450851:PHZ RS17210
gene id: 450851:PHZ_RS17210
uniprot id: B4RA07
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

450851:PHZ RS07780
gene id: 450851:PHZ_RS07780
uniprot id: B4R9R6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS13870
gene id: 450851:PHZ_RS13870
uniprot id: B4RGK7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

450851:PHZ RS03090
gene id: 450851:PHZ_RS03090
uniprot id: B4REZ8
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

450851:PHZ RS12740
gene id: 450851:PHZ_RS12740
uniprot id: B4RFE2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

450851:PHZ RS13925
gene id: 450851:PHZ_RS13925
uniprot id: B4RGL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS09625
gene id: 450851:PHZ_RS09625
uniprot id: B4RBW1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

450851:PHZ RS06720
gene id: 450851:PHZ_RS06720
uniprot id: B4R8J9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

450851:PHZ RS21265
gene id: 450851:PHZ_RS21265
uniprot id: B4RIT1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS20700
gene id: 450851:PHZ_RS20700
uniprot id: B4RIH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

450851:PHZ RS10270
gene id: 450851:PHZ_RS10270
uniprot id: B4RCT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

450851:PHZ RS21480
gene id: 450851:PHZ_RS21480
uniprot id: B4RGQ3
names: Subcellular Location Annotation
messages: Secreted

450851:PHZ RS15795
gene id: 450851:PHZ_RS15795
uniprot id: B4R8D9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS14810
gene id: 450851:PHZ_RS14810
uniprot id: B4RHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

450851:PHZ RS00535
gene id: 450851:PHZ_RS00535
uniprot id: B4RCB4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS15930
gene id: 450851:PHZ_RS15930
uniprot id: B4R8R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

450851:PHZ RS15845
gene id: 450851:PHZ_RS15845
uniprot id: B4R8Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

450851:PHZ RS17370
gene id: 450851:PHZ_RS17370
uniprot id: B4RA37
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS06805
gene id: 450851:PHZ_RS06805
uniprot id: B4R8L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

450851:PHZ RS17690
gene id: 450851:PHZ_RS17690
uniprot id: B4RAK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

450851:PHZ RS02915
gene id: 450851:PHZ_RS02915
uniprot id: B4REW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS06870
gene id: 450851:PHZ_RS06870
uniprot id: B4R8M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

450851:PHZ RS18845
gene id: 450851:PHZ_RS18845
uniprot id: B4RC21
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

450851:PHZ RS05435
gene id: 450851:PHZ_RS05435
uniprot id: B4RHE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

450851:PHZ RS04815
gene id: 450851:PHZ_RS04815
uniprot id: B4RGS9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS19295
gene id: 450851:PHZ_RS19295
uniprot id: B4RCA9
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS05075
gene id: 450851:PHZ_RS05075
uniprot id: B4RGX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

450851:PHZ RS04980
gene id: 450851:PHZ_RS04980
uniprot id: B4RGW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

450851:PHZ RS01730
gene id: 450851:PHZ_RS01730
uniprot id: B4RDM9
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

450851:PHZ RS01595
gene id: 450851:PHZ_RS01595
uniprot id: B4RDA1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS11500
gene id: 450851:PHZ_RS11500
uniprot id: B4RE73
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS02030
gene id: 450851:PHZ_RS02030
uniprot id: B4RDT6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

450851:PHZ RS04570
gene id: 450851:PHZ_RS04570
uniprot id: B4RGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

450851:PHZ RS03120
gene id: 450851:PHZ_RS03120
uniprot id: B4RF04
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

450851:PHZ RS09965
gene id: 450851:PHZ_RS09965
uniprot id: B4RCN3
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS04625
gene id: 450851:PHZ_RS04625
uniprot id: B4RGP3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

450851:PHZ RS18860
gene id: 450851:PHZ_RS18860
uniprot id: B4RC24
names: Similarity
messages: Belongs to the YciI family.

450851:PHZ RS10200
gene id: 450851:PHZ_RS10200
uniprot id: B4RCS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

450851:PHZ RS08375
gene id: 450851:PHZ_RS08375
uniprot id: B4RAC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

450851:PHZ RS10640
gene id: 450851:PHZ_RS10640
uniprot id: B4RDF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

450851:PHZ RS02455
gene id: 450851:PHZ_RS02455
uniprot id: B4REC5
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS15485
gene id: 450851:PHZ_RS15485
uniprot id: B4R883
names: Similarity
messages: Belongs to the peptidase M13 family.

450851:PHZ RS10840
gene id: 450851:PHZ_RS10840
uniprot id: B4RDJ4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

450851:PHZ RS03115
gene id: 450851:PHZ_RS03115
uniprot id: B4RF03
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

450851:PHZ RS11355
gene id: 450851:PHZ_RS11355
uniprot id: B4RE47
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

450851:PHZ RS03775
gene id: 450851:PHZ_RS03775
uniprot id: B4RFM9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS18080
gene id: 450851:PHZ_RS18080
uniprot id: B4RAS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

450851:PHZ RS07930
gene id: 450851:PHZ_RS07930
uniprot id: B4R9U2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

450851:PHZ RS02305
gene id: 450851:PHZ_RS02305
uniprot id: B4RE98
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS17435
gene id: 450851:PHZ_RS17435
uniprot id: B4RA50
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS20920
gene id: 450851:PHZ_RS20920
uniprot id: B4RIM3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

450851:PHZ RS01790
gene id: 450851:PHZ_RS01790
uniprot id: B4RDP1
names: Similarity
messages: Belongs to the class A bacterial acid phosphatase family.

450851:PHZ RS02900
gene id: 450851:PHZ_RS02900
uniprot id: B4REW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

450851:PHZ RS19910
gene id: 450851:PHZ_RS19910
uniprot id: B4RI35
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS15725
gene id: 450851:PHZ_RS15725
uniprot id: B4R8C6
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS04080
gene id: 450851:PHZ_RS04080
uniprot id: B4RG41
names: Subunit
messages: Homotetramer.

450851:PHZ RS10655
gene id: 450851:PHZ_RS10655
uniprot id: B4RDF9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS01085
gene id: 450851:PHZ_RS01085
uniprot id: B4RCL4
names: Similarity
messages: Belongs to the thioredoxin family.

450851:PHZ RS11605
gene id: 450851:PHZ_RS11605
uniprot id: B4REJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS02460
gene id: 450851:PHZ_RS02460
uniprot id: B4REC6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

450851:PHZ RS16505
gene id: 450851:PHZ_RS16505
uniprot id: B4R9C4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

450851:PHZ RS00870
gene id: 450851:PHZ_RS00870
uniprot id: B4RCH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

450851:PHZ RS07285
gene id: 450851:PHZ_RS07285
uniprot id: B4R967
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

450851:PHZ RS04110
gene id: 450851:PHZ_RS04110
uniprot id: B4RG46
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

450851:PHZ RS16670
gene id: 450851:PHZ_RS16670
uniprot id: B4R9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS08970
gene id: 450851:PHZ_RS08970
uniprot id: B4RAY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

450851:PHZ RS17475
gene id: 450851:PHZ_RS17475
uniprot id: B4RA57
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

450851:PHZ RS00220
gene id: 450851:PHZ_RS00220
uniprot id: B4RBJ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

450851:PHZ RS21205
gene id: 450851:PHZ_RS21205
uniprot id: B4RIR8
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

450851:PHZ RS13035
gene id: 450851:PHZ_RS13035
uniprot id: B4RFV3
names: Similarity
messages: Belongs to the GSP E family.

450851:PHZ RS11055
gene id: 450851:PHZ_RS11055
uniprot id: B4RDZ2
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

450851:PHZ RS04890
gene id: 450851:PHZ_RS04890
uniprot id: B4RGU2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

450851:PHZ RS05975
gene id: 450851:PHZ_RS05975
uniprot id: B4R7W9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

450851:PHZ RS10790
gene id: 450851:PHZ_RS10790
uniprot id: B4RDI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

450851:PHZ RS10150
gene id: 450851:PHZ_RS10150
uniprot id: B4RCR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

450851:PHZ RS15375
gene id: 450851:PHZ_RS15375
uniprot id: B4R865
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS15010
gene id: 450851:PHZ_RS15010
uniprot id: B4RHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

450851:PHZ RS00025
gene id: 450851:PHZ_RS00025
uniprot id: B4RBF9
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

450851:PHZ RS09785
gene id: 450851:PHZ_RS09785
uniprot id: B4RBZ2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS07675
gene id: 450851:PHZ_RS07675
uniprot id: B4R9P6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

450851:PHZ RS03710
gene id: 450851:PHZ_RS03710
uniprot id: B4RFL8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

450851:PHZ RS13660
gene id: 450851:PHZ_RS13660
uniprot id: B4RGG5
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

450851:PHZ RS20295
gene id: 450851:PHZ_RS20295
uniprot id: B4RIA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.
messages: Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.

450851:PHZ RS12370
gene id: 450851:PHZ_RS12370
uniprot id: B4RF77
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

450851:PHZ RS12895
gene id: 450851:PHZ_RS12895
uniprot id: B4RFS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

450851:PHZ RS13915
gene id: 450851:PHZ_RS13915
uniprot id: B4RGL6
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS16405
gene id: 450851:PHZ_RS16405
uniprot id: B4R901
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

450851:PHZ RS09745
gene id: 450851:PHZ_RS09745
uniprot id: B4RBY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

450851:PHZ RS02280
gene id: 450851:PHZ_RS02280
uniprot id: B4RE92
names: Similarity
messages: Belongs to the sulfatase family.

450851:PHZ RS01110
gene id: 450851:PHZ_RS01110
uniprot id: B4RD14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

450851:PHZ RS00900
gene id: 450851:PHZ_RS00900
uniprot id: B4RCI2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

450851:PHZ RS16150
gene id: 450851:PHZ_RS16150
uniprot id: B4R8V3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

450851:PHZ RS03845
gene id: 450851:PHZ_RS03845
uniprot id: B4RFP1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

450851:PHZ RS07480
gene id: 450851:PHZ_RS07480
uniprot id: B4R9A3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

450851:PHZ RS05420
gene id: 450851:PHZ_RS05420
uniprot id: B4RHE5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

450851:PHZ RS00585
gene id: 450851:PHZ_RS00585
uniprot id: B4RCC3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS19255
gene id: 450851:PHZ_RS19255
uniprot id: B4RCA1
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS15640
gene id: 450851:PHZ_RS15640
uniprot id: B4R8B1
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS10280
gene id: 450851:PHZ_RS10280
uniprot id: B4RCU1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

450851:PHZ RS10785
gene id: 450851:PHZ_RS10785
uniprot id: B4RDI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

450851:PHZ RS08940
gene id: 450851:PHZ_RS08940
uniprot id: B4RAY0
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

450851:PHZ RS10015
gene id: 450851:PHZ_RS10015
uniprot id: B4RCP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

450851:PHZ RS19175
gene id: 450851:PHZ_RS19175
uniprot id: B4RC85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

450851:PHZ RS09675
gene id: 450851:PHZ_RS09675
uniprot id: B4RBX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

450851:PHZ RS00270
gene id: 450851:PHZ_RS00270
uniprot id: B4RBK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS04405
gene id: 450851:PHZ_RS04405
uniprot id: B4RG98
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

450851:PHZ RS06565
gene id: 450851:PHZ_RS06565
uniprot id: B4R8H6
names: Similarity
messages: Belongs to the UPF0178 family.

450851:PHZ RS19220
gene id: 450851:PHZ_RS19220
uniprot id: B4RC94
names: Similarity
messages: Belongs to the UPF0162 family.

450851:PHZ RS12840
gene id: 450851:PHZ_RS12840
uniprot id: B4RFG0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

450851:PHZ RS03050
gene id: 450851:PHZ_RS03050
uniprot id: B4REZ0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

450851:PHZ RS05550
gene id: 450851:PHZ_RS05550
uniprot id: B4RHG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

450851:PHZ RS00515
gene id: 450851:PHZ_RS00515
uniprot id: B4RBP9
names: Similarity
messages: Belongs to the acylphosphatase family.

450851:PHZ RS15500
gene id: 450851:PHZ_RS15500
uniprot id: B4R886
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

450851:PHZ RS17165
gene id: 450851:PHZ_RS17165
uniprot id: B4R9Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

450851:PHZ RS12645
gene id: 450851:PHZ_RS12645
uniprot id: B4RFC6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

450851:PHZ RS03680
gene id: 450851:PHZ_RS03680
uniprot id: B4RFL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

450851:PHZ RS10825
gene id: 450851:PHZ_RS10825
uniprot id: B4RDJ1
names: Similarity
messages: Belongs to the AHA1 family.

450851:PHZ RS13540
gene id: 450851:PHZ_RS13540
uniprot id: B4RGE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS14315
gene id: 450851:PHZ_RS14315
uniprot id: B4RH48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS11155
gene id: 450851:PHZ_RS11155
uniprot id: B4RE11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

450851:PHZ RS02345
gene id: 450851:PHZ_RS02345
uniprot id: B4REA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

450851:PHZ RS12095
gene id: 450851:PHZ_RS12095
uniprot id: B4RET4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

450851:PHZ RS07405
gene id: 450851:PHZ_RS07405
uniprot id: B4R988
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

450851:PHZ RS15945
gene id: 450851:PHZ_RS15945
uniprot id: B4R8S0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

450851:PHZ RS08455
gene id: 450851:PHZ_RS08455
uniprot id: B4RAD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

450851:PHZ RS19770
gene id: 450851:PHZ_RS19770
uniprot id: B4RI07
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

450851:PHZ RS05665
gene id: 450851:PHZ_RS05665
uniprot id: B4RHI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS06915
gene id: 450851:PHZ_RS06915
uniprot id: B4R8N8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

450851:PHZ RS04225
gene id: 450851:PHZ_RS04225
uniprot id: B4RG68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

450851:PHZ RS14450
gene id: 450851:PHZ_RS14450
uniprot id: B4RH72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

450851:PHZ RS07760
gene id: 450851:PHZ_RS07760
uniprot id: B4R9R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

450851:PHZ RS17270
gene id: 450851:PHZ_RS17270
uniprot id: B4RA18
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS02925
gene id: 450851:PHZ_RS02925
uniprot id: B4REW7
names: Similarity
messages: Belongs to the peptidase U62 family.

450851:PHZ RS16440
gene id: 450851:PHZ_RS16440
uniprot id: B4R907
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS09905
gene id: 450851:PHZ_RS09905
uniprot id: B4RCM3
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

450851:PHZ RS03540
gene id: 450851:PHZ_RS03540
uniprot id: B4RFI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

450851:PHZ RS16735
gene id: 450851:PHZ_RS16735
uniprot id: B4R9G8
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

450851:PHZ RS03760
gene id: 450851:PHZ_RS03760
uniprot id: B4RFM6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

450851:PHZ RS08595
gene id: 450851:PHZ_RS08595
uniprot id: B4RAG4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

450851:PHZ RS05460
gene id: 450851:PHZ_RS05460
uniprot id: B4RHF3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

450851:PHZ RS10960
gene id: 450851:PHZ_RS10960
uniprot id: B4RDL7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

450851:PHZ RS07900
gene id: 450851:PHZ_RS07900
uniprot id: B4R9T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

450851:PHZ RS18840
gene id: 450851:PHZ_RS18840
uniprot id: B4RC20
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

450851:PHZ RS11130
gene id: 450851:PHZ_RS11130
uniprot id: B4RE06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

450851:PHZ RS09840
gene id: 450851:PHZ_RS09840
uniprot id: B4RC01
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

450851:PHZ RS08585
gene id: 450851:PHZ_RS08585
uniprot id: B4RAG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

450851:PHZ RS04745
gene id: 450851:PHZ_RS04745
uniprot id: B4RGR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

450851:PHZ RS16630
gene id: 450851:PHZ_RS16630
uniprot id: B4R9E7
names: Similarity
messages: Belongs to the bacterial secretin family.

450851:PHZ RS12825
gene id: 450851:PHZ_RS12825
uniprot id: B4RFF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

450851:PHZ RS09610
gene id: 450851:PHZ_RS09610
uniprot id: B4RBV8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

450851:PHZ RS19170
gene id: 450851:PHZ_RS19170
uniprot id: B4RC84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

450851:PHZ RS18875
gene id: 450851:PHZ_RS18875
uniprot id: B4RC27
names: Similarity
messages: Belongs to the creatininase superfamily.

450851:PHZ RS00505
gene id: 450851:PHZ_RS00505
uniprot id: B4RBP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

450851:PHZ RS02970
gene id: 450851:PHZ_RS02970
uniprot id: B4REX5
names: Similarity
messages: Belongs to the threonine synthase family.

450851:PHZ RS06935
gene id: 450851:PHZ_RS06935
uniprot id: B4R8P2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

450851:PHZ RS02385
gene id: 450851:PHZ_RS02385
uniprot id: B4REB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

450851:PHZ RS00750
gene id: 450851:PHZ_RS00750
uniprot id: B4RCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

450851:PHZ RS05250
gene id: 450851:PHZ_RS05250
uniprot id: B4RHB6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS09080
gene id: 450851:PHZ_RS09080
uniprot id: B4RB04
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS09280
gene id: 450851:PHZ_RS09280
uniprot id: B4RB40
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS00735
gene id: 450851:PHZ_RS00735
uniprot id: B4RCF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

450851:PHZ RS00445
gene id: 450851:PHZ_RS00445
uniprot id: B4RBN5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

450851:PHZ RS17750
gene id: 450851:PHZ_RS17750
uniprot id: B4RAL4
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS01970
gene id: 450851:PHZ_RS01970
uniprot id: B4RDS4
names: Similarity
messages: Belongs to the peptidase C40 family.

450851:PHZ RS19610
gene id: 450851:PHZ_RS19610
uniprot id: B4RHY5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

450851:PHZ RS05565
gene id: 450851:PHZ_RS05565
uniprot id: B4RHH2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

450851:PHZ RS01765
gene id: 450851:PHZ_RS01765
uniprot id: B4RDN6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

450851:PHZ RS13635
gene id: 450851:PHZ_RS13635
uniprot id: B4RGG0
names: Similarity
messages: Belongs to the UxaA family.

450851:PHZ RS09555
gene id: 450851:PHZ_RS09555
uniprot id: B4RBU7
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS13370
gene id: 450851:PHZ_RS13370
uniprot id: B4RG04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS16075
gene id: 450851:PHZ_RS16075
uniprot id: B4R8U3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

450851:PHZ RS12680
gene id: 450851:PHZ_RS12680
uniprot id: B4RFD2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS13950
gene id: 450851:PHZ_RS13950
uniprot id: B4RGM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS06620
gene id: 450851:PHZ_RS06620
uniprot id: B4R8I4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS09830
gene id: 450851:PHZ_RS09830
uniprot id: B4RBZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS09160
gene id: 450851:PHZ_RS09160
uniprot id: B4RB18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

450851:PHZ RS16790
gene id: 450851:PHZ_RS16790
uniprot id: B4R9H9
names: Similarity
messages: Belongs to the GSP E family.

450851:PHZ RS07690
gene id: 450851:PHZ_RS07690
uniprot id: B4R9P9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

450851:PHZ RS08580
gene id: 450851:PHZ_RS08580
uniprot id: B4RAG1
names: Similarity
messages: Belongs to the fabD family.

450851:PHZ RS12865
gene id: 450851:PHZ_RS12865
uniprot id: B4RFS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

450851:PHZ RS15195
gene id: 450851:PHZ_RS15195
uniprot id: B4RHW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

450851:PHZ RS00860
gene id: 450851:PHZ_RS00860
uniprot id: B4RCH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

450851:PHZ RS07470
gene id: 450851:PHZ_RS07470
uniprot id: B4R9A1
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

450851:PHZ RS12345
gene id: 450851:PHZ_RS12345
uniprot id: B4RF72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

450851:PHZ RS00495
gene id: 450851:PHZ_RS00495
uniprot id: B4RBP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

450851:PHZ RS16165
gene id: 450851:PHZ_RS16165
uniprot id: B4R8V6
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

450851:PHZ RS15860
gene id: 450851:PHZ_RS15860
uniprot id: B4R8Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

450851:PHZ RS04085
gene id: 450851:PHZ_RS04085
uniprot id: B4RG42
names: Similarity
messages: Belongs to the peptidase S33 family.

450851:PHZ RS14205
gene id: 450851:PHZ_RS14205
uniprot id: B4RH30
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

450851:PHZ RS09190
gene id: 450851:PHZ_RS09190
uniprot id: B4RB24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

450851:PHZ RS03560
gene id: 450851:PHZ_RS03560
uniprot id: B4RFJ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

450851:PHZ RS18265
gene id: 450851:PHZ_RS18265
uniprot id: B4RB63
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS06675
gene id: 450851:PHZ_RS06675
uniprot id: B4R8J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

450851:PHZ RS03185
gene id: 450851:PHZ_RS03185
uniprot id: B4RF17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

450851:PHZ RS18850
gene id: 450851:PHZ_RS18850
uniprot id: B4RC22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

450851:PHZ RS06660
gene id: 450851:PHZ_RS06660
uniprot id: B4R8J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

450851:PHZ RS00855
gene id: 450851:PHZ_RS00855
uniprot id: B4RCH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

450851:PHZ RS02995
gene id: 450851:PHZ_RS02995
uniprot id: B4REY0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

450851:PHZ RS07290
gene id: 450851:PHZ_RS07290
uniprot id: B4R968
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

450851:PHZ RS03800
gene id: 450851:PHZ_RS03800
uniprot id: B4RFN3
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

450851:PHZ RS04485
gene id: 450851:PHZ_RS04485
uniprot id: B4RGB2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

450851:PHZ RS08925
gene id: 450851:PHZ_RS08925
uniprot id: B4RAX7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS05805
gene id: 450851:PHZ_RS05805
uniprot id: B4RHL2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

450851:PHZ RS17755
gene id: 450851:PHZ_RS17755
uniprot id: B4RAL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

450851:PHZ RS03160
gene id: 450851:PHZ_RS03160
uniprot id: B4RF12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

450851:PHZ RS04780
gene id: 450851:PHZ_RS04780
uniprot id: B4RGS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

450851:PHZ RS03725
gene id: 450851:PHZ_RS03725
uniprot id: B4RFM1
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS08145
gene id: 450851:PHZ_RS08145
uniprot id: B4RA86
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS13860
gene id: 450851:PHZ_RS13860
uniprot id: B4RGK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS11775
gene id: 450851:PHZ_RS11775
uniprot id: B4REM9
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS03150
gene id: 450851:PHZ_RS03150
uniprot id: B4RF10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

450851:PHZ RS19440
gene id: 450851:PHZ_RS19440
uniprot id: B4RCZ7
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

450851:PHZ RS03190
gene id: 450851:PHZ_RS03190
uniprot id: B4RF18
names: Similarity
messages: Belongs to the GcvT family.

450851:PHZ RS02720
gene id: 450851:PHZ_RS02720
uniprot id: B4REH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

450851:PHZ RS06890
gene id: 450851:PHZ_RS06890
uniprot id: B4R8N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

450851:PHZ RS06535
gene id: 450851:PHZ_RS06535
uniprot id: B4R8H0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

450851:PHZ RS12530
gene id: 450851:PHZ_RS12530
uniprot id: B4RFA4
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

450851:PHZ RS12845
gene id: 450851:PHZ_RS12845
uniprot id: B4RFG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

450851:PHZ RS13665
gene id: 450851:PHZ_RS13665
uniprot id: B4RGG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

450851:PHZ RS17470
gene id: 450851:PHZ_RS17470
uniprot id: B4RA56
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

450851:PHZ RS14255
gene id: 450851:PHZ_RS14255
uniprot id: B4RH36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

450851:PHZ RS09860
gene id: 450851:PHZ_RS09860
uniprot id: B4RC05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

450851:PHZ RS17145
gene id: 450851:PHZ_RS17145
uniprot id: B4R9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

450851:PHZ RS19930
gene id: 450851:PHZ_RS19930
uniprot id: B4RI38
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

450851:PHZ RS14725
gene id: 450851:PHZ_RS14725
uniprot id: B4RHM5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

450851:PHZ RS00425
gene id: 450851:PHZ_RS00425
uniprot id: B4RBN1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

450851:PHZ RS11785
gene id: 450851:PHZ_RS11785
uniprot id: B4REN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

450851:PHZ RS02290
gene id: 450851:PHZ_RS02290
uniprot id: B4RE95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS09700
gene id: 450851:PHZ_RS09700
uniprot id: B4RBX5
names: Similarity
messages: Belongs to the TrpC family.

450851:PHZ RS09265
gene id: 450851:PHZ_RS09265
uniprot id: B4RB37
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

450851:PHZ RS04870
gene id: 450851:PHZ_RS04870
uniprot id: B4RGT8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS03525
gene id: 450851:PHZ_RS03525
uniprot id: B4RFI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS14110
gene id: 450851:PHZ_RS14110
uniprot id: B4RH13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS20985
gene id: 450851:PHZ_RS20985
uniprot id: B4RIN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS02990
gene id: 450851:PHZ_RS02990
uniprot id: B4REX9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

450851:PHZ RS18205
gene id: 450851:PHZ_RS18205
uniprot id: B4RB51
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

450851:PHZ RS01030
gene id: 450851:PHZ_RS01030
uniprot id: B4RCK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

450851:PHZ RS04710
gene id: 450851:PHZ_RS04710
uniprot id: B4RGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

450851:PHZ RS02410
gene id: 450851:PHZ_RS02410
uniprot id: B4REB9
names: Similarity
messages: Belongs to the peptidase S58 family.

450851:PHZ RS17575
gene id: 450851:PHZ_RS17575
uniprot id: B4RA76
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS17715
gene id: 450851:PHZ_RS17715
uniprot id: B4RAK7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

450851:PHZ RS00440
gene id: 450851:PHZ_RS00440
uniprot id: B4RBN4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

450851:PHZ RS18435
gene id: 450851:PHZ_RS18435
uniprot id: B4RB96
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS19265
gene id: 450851:PHZ_RS19265
uniprot id: B4RCA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

450851:PHZ RS06020
gene id: 450851:PHZ_RS06020
uniprot id: B4R7X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

450851:PHZ RS08050
gene id: 450851:PHZ_RS08050
uniprot id: B4R9W1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

450851:PHZ RS09485
gene id: 450851:PHZ_RS09485
uniprot id: B4RBT4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

450851:PHZ RS15585
gene id: 450851:PHZ_RS15585
uniprot id: B4R8A2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

450851:PHZ RS17740
gene id: 450851:PHZ_RS17740
uniprot id: B4RAL2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

450851:PHZ RS07505
gene id: 450851:PHZ_RS07505
uniprot id: B4R9A8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

450851:PHZ RS14350
gene id: 450851:PHZ_RS14350
uniprot id: B4RH54
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

450851:PHZ RS00205
gene id: 450851:PHZ_RS00205
uniprot id: B4RBJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

450851:PHZ RS10265
gene id: 450851:PHZ_RS10265
uniprot id: B4RCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

450851:PHZ RS13305
gene id: 450851:PHZ_RS13305
uniprot id: B4RFZ0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

450851:PHZ RS13865
gene id: 450851:PHZ_RS13865
uniprot id: B4RGK6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS15430
gene id: 450851:PHZ_RS15430
uniprot id: B4R875
names: Similarity
messages: Belongs to the peptidase S33 family.

450851:PHZ RS10565
gene id: 450851:PHZ_RS10565
uniprot id: B4RDE2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS16330
gene id: 450851:PHZ_RS16330
uniprot id: B4R8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS19600
gene id: 450851:PHZ_RS19600
uniprot id: B4RHY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm
messages: Part of the Type IV secretion system.

450851:PHZ RS16520
gene id: 450851:PHZ_RS16520
uniprot id: B4R9C7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

450851:PHZ RS01035
gene id: 450851:PHZ_RS01035
uniprot id: B4RCK5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

450851:PHZ RS13760
gene id: 450851:PHZ_RS13760
uniprot id: B4RGI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

450851:PHZ RS18820
gene id: 450851:PHZ_RS18820
uniprot id: B4RC16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS01155
gene id: 450851:PHZ_RS01155
uniprot id: B4RD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS09910
gene id: 450851:PHZ_RS09910
uniprot id: B4RCM4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

450851:PHZ RS12665
gene id: 450851:PHZ_RS12665
uniprot id: B4RFD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

450851:PHZ RS18960
gene id: 450851:PHZ_RS18960
uniprot id: B4RC43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

450851:PHZ RS18085
gene id: 450851:PHZ_RS18085
uniprot id: B4RAS4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

450851:PHZ RS04715
gene id: 450851:PHZ_RS04715
uniprot id: B4RGR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

450851:PHZ RS19780
gene id: 450851:PHZ_RS19780
uniprot id: B4RI09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

450851:PHZ RS05195
gene id: 450851:PHZ_RS05195
uniprot id: B4RHA6
names: Similarity
messages: Belongs to the LOG family.

450851:PHZ RS10045
gene id: 450851:PHZ_RS10045
uniprot id: B4RCP6
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS09520
gene id: 450851:PHZ_RS09520
uniprot id: B4RBU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

450851:PHZ RS07300
gene id: 450851:PHZ_RS07300
uniprot id: B4R970
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

450851:PHZ RS14280
gene id: 450851:PHZ_RS14280
uniprot id: B4RH41
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

450851:PHZ RS18250
gene id: 450851:PHZ_RS18250
uniprot id: B4RB60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

450851:PHZ RS05260
gene id: 450851:PHZ_RS05260
uniprot id: B4RHB8
names: Similarity
messages: Belongs to the peptidase S9C family.

450851:PHZ RS09230
gene id: 450851:PHZ_RS09230
uniprot id: B4RB31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS03320
gene id: 450851:PHZ_RS03320
uniprot id: B4RF41
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

450851:PHZ RS00400
gene id: 450851:PHZ_RS00400
uniprot id: B4RBM6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

450851:PHZ RS08035
gene id: 450851:PHZ_RS08035
uniprot id: B4R9V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

450851:PHZ RS00370
gene id: 450851:PHZ_RS00370
uniprot id: B4RBM0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

450851:PHZ RS16795
gene id: 450851:PHZ_RS16795
uniprot id: B4R9I0
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS16665
gene id: 450851:PHZ_RS16665
uniprot id: B4R9F4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS03515
gene id: 450851:PHZ_RS03515
uniprot id: B4RFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS18180
gene id: 450851:PHZ_RS18180
uniprot id: B4RAU3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

450851:PHZ RS06420
gene id: 450851:PHZ_RS06420
uniprot id: B4R8E8
names: Similarity
messages: Belongs to the peptidase M13 family.

450851:PHZ RS12855
gene id: 450851:PHZ_RS12855
uniprot id: B4RFS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

450851:PHZ RS11975
gene id: 450851:PHZ_RS11975
uniprot id: B4RER6
names: Similarity
messages: Belongs to the SBNO family.

450851:PHZ RS07660
gene id: 450851:PHZ_RS07660
uniprot id: B4R9P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

450851:PHZ RS03505
gene id: 450851:PHZ_RS03505
uniprot id: B4RFI1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

450851:PHZ RS05785
gene id: 450851:PHZ_RS05785
uniprot id: B4RHK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

450851:PHZ RS19505
gene id: 450851:PHZ_RS19505
uniprot id: B4RD09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

450851:PHZ RS17480
gene id: 450851:PHZ_RS17480
uniprot id: B4RA58
names: Similarity
messages: Belongs to the YciI family.

450851:PHZ RS03785
gene id: 450851:PHZ_RS03785
uniprot id: B4RFN1
names: Similarity
messages: Belongs to the group II decarboxylase family.

450851:PHZ RS03080
gene id: 450851:PHZ_RS03080
uniprot id: B4REZ6
names: Similarity
messages: Belongs to the YciI family.

450851:PHZ RS10170
gene id: 450851:PHZ_RS10170
uniprot id: B4RCS0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS14080
gene id: 450851:PHZ_RS14080
uniprot id: B4RH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS05490
gene id: 450851:PHZ_RS05490
uniprot id: B4RHF8
names: Similarity
messages: Belongs to the DSD1 family.

450851:PHZ RS02140
gene id: 450851:PHZ_RS02140
uniprot id: B4RDV7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

450851:PHZ RS19840
gene id: 450851:PHZ_RS19840
uniprot id: B4RI21
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

450851:PHZ RS18555
gene id: 450851:PHZ_RS18555
uniprot id: B4RBB8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS05950
gene id: 450851:PHZ_RS05950
uniprot id: B4R7W5
names: Similarity
messages: Belongs to the peptidase S8 family.

450851:PHZ RS17400
gene id: 450851:PHZ_RS17400
uniprot id: B4RA43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

450851:PHZ RS04795
gene id: 450851:PHZ_RS04795
uniprot id: B4RGS5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

450851:PHZ RS05310
gene id: 450851:PHZ_RS05310
uniprot id: B4RHC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS00275
gene id: 450851:PHZ_RS00275
uniprot id: B4RBK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS09705
gene id: 450851:PHZ_RS09705
uniprot id: B4RBX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

450851:PHZ RS07965
gene id: 450851:PHZ_RS07965
uniprot id: B4R9U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS07510
gene id: 450851:PHZ_RS07510
uniprot id: B4R9A9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

450851:PHZ RS01490
gene id: 450851:PHZ_RS01490
uniprot id: B4RD80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

450851:PHZ RS06955
gene id: 450851:PHZ_RS06955
uniprot id: B4R8P6
names: Similarity
messages: Belongs to the AHA1 family.

450851:PHZ RS17465
gene id: 450851:PHZ_RS17465
uniprot id: B4RA55
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

450851:PHZ RS03035
gene id: 450851:PHZ_RS03035
uniprot id: B4REY8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS08360
gene id: 450851:PHZ_RS08360
uniprot id: B4RAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

450851:PHZ RS17735
gene id: 450851:PHZ_RS17735
uniprot id: B4RAL1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS04915
gene id: 450851:PHZ_RS04915
uniprot id: B4RGU7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

450851:PHZ RS16340
gene id: 450851:PHZ_RS16340
uniprot id: B4R8Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

450851:PHZ RS20485
gene id: 450851:PHZ_RS20485
uniprot id: B4RID9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

450851:PHZ RS21375
gene id: 450851:PHZ_RS21375
uniprot id: B4RCF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

450851:PHZ RS12585
gene id: 450851:PHZ_RS12585
uniprot id: B4RFB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

450851:PHZ RS18020
gene id: 450851:PHZ_RS18020
uniprot id: B4RAR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

450851:PHZ RS16020
gene id: 450851:PHZ_RS16020
uniprot id: B4R8T4
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

450851:PHZ RS06895
gene id: 450851:PHZ_RS06895
uniprot id: B4R8N4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

450851:PHZ RS19595
gene id: 450851:PHZ_RS19595
uniprot id: B4RHY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

450851:PHZ RS16780
gene id: 450851:PHZ_RS16780
uniprot id: B4R9H7
names: Similarity
messages: Belongs to the bacterial secretin family.

450851:PHZ RS10360
gene id: 450851:PHZ_RS10360
uniprot id: B4RCV6
names: Similarity
messages: Belongs to the YciI family.

450851:PHZ RS08265
gene id: 450851:PHZ_RS08265
uniprot id: B4RAA2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

450851:PHZ RS09210
gene id: 450851:PHZ_RS09210
uniprot id: B4RB28
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

450851:PHZ RS19580
gene id: 450851:PHZ_RS19580
uniprot id: B4RHY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

450851:PHZ RS02125
gene id: 450851:PHZ_RS02125
uniprot id: B4RDV4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

450851:PHZ RS02760
gene id: 450851:PHZ_RS02760
uniprot id: B4REI3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

450851:PHZ RS01305
gene id: 450851:PHZ_RS01305
uniprot id: B4RD44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

450851:PHZ RS13680
gene id: 450851:PHZ_RS13680
uniprot id: B4RGG9
names: Similarity
messages: Belongs to the IlvD/Edd family.

450851:PHZ RS15705
gene id: 450851:PHZ_RS15705
uniprot id: B4R8C2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

450851:PHZ RS15880
gene id: 450851:PHZ_RS15880
uniprot id: B4R8Q9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

450851:PHZ RS05520
gene id: 450851:PHZ_RS05520
uniprot id: B4RHG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

450851:PHZ RS04360
gene id: 450851:PHZ_RS04360
uniprot id: B4RG89
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS12445
gene id: 450851:PHZ_RS12445
uniprot id: B4RF90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the haloalkane dehalogenase family. Type 1 subfamily.
messages: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
messages: Monomer.

450851:PHZ RS02975
gene id: 450851:PHZ_RS02975
uniprot id: B4REX6
names: Similarity
messages: Belongs to the peptidase M16 family.

450851:PHZ RS14805
gene id: 450851:PHZ_RS14805
uniprot id: B4RHN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

450851:PHZ RS10485
gene id: 450851:PHZ_RS10485
uniprot id: B4RDC8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

450851:PHZ RS17525
gene id: 450851:PHZ_RS17525
uniprot id: B4RA67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

450851:PHZ RS17320
gene id: 450851:PHZ_RS17320
uniprot id: B4RA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

450851:PHZ RS03980
gene id: 450851:PHZ_RS03980
uniprot id: B4RFR4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS18295
gene id: 450851:PHZ_RS18295
uniprot id: B4RB69
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

450851:PHZ RS18495
gene id: 450851:PHZ_RS18495
uniprot id: B4RBA7
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

450851:PHZ RS08370
gene id: 450851:PHZ_RS08370
uniprot id: B4RAC3
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

450851:PHZ RS23290
gene id: 450851:PHZ_RS23290
uniprot id: B4RI80
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

450851:PHZ RS10395
gene id: 450851:PHZ_RS10395
uniprot id: B4RCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

450851:PHZ RS13970
gene id: 450851:PHZ_RS13970
uniprot id: B4RGM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS03055
gene id: 450851:PHZ_RS03055
uniprot id: B4REZ1
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS10915
gene id: 450851:PHZ_RS10915
uniprot id: B4RDK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

450851:PHZ RS08660
gene id: 450851:PHZ_RS08660
uniprot id: B4RAH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

450851:PHZ RS04320
gene id: 450851:PHZ_RS04320
uniprot id: B4RG83
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

450851:PHZ RS12780
gene id: 450851:PHZ_RS12780
uniprot id: B4RFE9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

450851:PHZ RS07610
gene id: 450851:PHZ_RS07610
uniprot id: B4R9N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: In C.crescentus, the flagellar filament is composed of multiple flagellins of 29 kDa; 27 kDa and 25 kDa.
messages: Secreted

450851:PHZ RS15875
gene id: 450851:PHZ_RS15875
uniprot id: B4R8Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

450851:PHZ RS01770
gene id: 450851:PHZ_RS01770
uniprot id: B4RDN7
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS21030
gene id: 450851:PHZ_RS21030
uniprot id: B4RIP3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

450851:PHZ RS11045
gene id: 450851:PHZ_RS11045
uniprot id: B4RDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS20915
gene id: 450851:PHZ_RS20915
uniprot id: B4RIM2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

450851:PHZ RS18910
gene id: 450851:PHZ_RS18910
uniprot id: B4RC34
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

450851:PHZ RS17330
gene id: 450851:PHZ_RS17330
uniprot id: B4RA30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

450851:PHZ RS18715
gene id: 450851:PHZ_RS18715
uniprot id: B4RBE6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

450851:PHZ RS04055
gene id: 450851:PHZ_RS04055
uniprot id: B4RG36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

450851:PHZ RS01025
gene id: 450851:PHZ_RS01025
uniprot id: B4RCK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

450851:PHZ RS19460
gene id: 450851:PHZ_RS19460
uniprot id: B4RD01
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

450851:PHZ RS09515
gene id: 450851:PHZ_RS09515
uniprot id: B4RBT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

450851:PHZ RS03545
gene id: 450851:PHZ_RS03545
uniprot id: B4RFI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

450851:PHZ RS09570
gene id: 450851:PHZ_RS09570
uniprot id: B4RBV0
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

450851:PHZ RS00605
gene id: 450851:PHZ_RS00605
uniprot id: B4RCC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

450851:PHZ RS01905
gene id: 450851:PHZ_RS01905
uniprot id: B4RDR1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS20305
gene id: 450851:PHZ_RS20305
uniprot id: B4RIA4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

450851:PHZ RS16175
gene id: 450851:PHZ_RS16175
uniprot id: B4R8V8
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS09925
gene id: 450851:PHZ_RS09925
uniprot id: B4RCM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

450851:PHZ RS08350
gene id: 450851:PHZ_RS08350
uniprot id: B4RAB9
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

450851:PHZ RS07775
gene id: 450851:PHZ_RS07775
uniprot id: B4R9R5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

450851:PHZ RS06845
gene id: 450851:PHZ_RS06845
uniprot id: B4R8M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

450851:PHZ RS09180
gene id: 450851:PHZ_RS09180
uniprot id: B4RB22
names: Similarity
messages: Belongs to the UPF0174 family.

450851:PHZ RS06445
gene id: 450851:PHZ_RS06445
uniprot id: B4R8F3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS07490
gene id: 450851:PHZ_RS07490
uniprot id: B4R9A5
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

450851:PHZ RS16730
gene id: 450851:PHZ_RS16730
uniprot id: B4R9G7
names: Cofactor
messages: Binds 2 iron ions per subunit.

450851:PHZ RS11070
gene id: 450851:PHZ_RS11070
uniprot id: B4RDZ5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS10905
gene id: 450851:PHZ_RS10905
uniprot id: B4RDK7
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

450851:PHZ RS09345
gene id: 450851:PHZ_RS09345
uniprot id: B4RBQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

450851:PHZ RS06490
gene id: 450851:PHZ_RS06490
uniprot id: B4R8G1
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS09710
gene id: 450851:PHZ_RS09710
uniprot id: B4RBX7
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS08820
gene id: 450851:PHZ_RS08820
uniprot id: B4RAV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

450851:PHZ RS04765
gene id: 450851:PHZ_RS04765
uniprot id: B4RGR9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

450851:PHZ RS09980
gene id: 450851:PHZ_RS09980
uniprot id: B4RCN6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

450851:PHZ RS13670
gene id: 450851:PHZ_RS13670
uniprot id: B4RGG7
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS10910
gene id: 450851:PHZ_RS10910
uniprot id: B4RDK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

450851:PHZ RS16050
gene id: 450851:PHZ_RS16050
uniprot id: B4R8T9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

450851:PHZ RS11265
gene id: 450851:PHZ_RS11265
uniprot id: B4RE31
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS18055
gene id: 450851:PHZ_RS18055
uniprot id: B4RAR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

450851:PHZ RS11505
gene id: 450851:PHZ_RS11505
uniprot id: B4RE74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS02370
gene id: 450851:PHZ_RS02370
uniprot id: B4REB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

450851:PHZ RS19480
gene id: 450851:PHZ_RS19480
uniprot id: B4RD04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

450851:PHZ RS19000
gene id: 450851:PHZ_RS19000
uniprot id: B4RC51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

450851:PHZ RS17455
gene id: 450851:PHZ_RS17455
uniprot id: B4RA54
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

450851:PHZ RS19940
gene id: 450851:PHZ_RS19940
uniprot id: B4RI39
names: Similarity
messages: Belongs to the thioredoxin family.

450851:PHZ RS00170
gene id: 450851:PHZ_RS00170
uniprot id: B4RBI5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

450851:PHZ RS19475
gene id: 450851:PHZ_RS19475
uniprot id: B4RD03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

450851:PHZ RS06025
gene id: 450851:PHZ_RS06025
uniprot id: B4R7X9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

450851:PHZ RS16310
gene id: 450851:PHZ_RS16310
uniprot id: B4R8Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

450851:PHZ RS14665
gene id: 450851:PHZ_RS14665
uniprot id: B4RHL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

450851:PHZ RS00020
gene id: 450851:PHZ_RS00020
uniprot id: B4RBF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

450851:PHZ RS13880
gene id: 450851:PHZ_RS13880
uniprot id: B4RGK9
names: Similarity
messages: Belongs to the peptidase S9C family.

450851:PHZ RS04060
gene id: 450851:PHZ_RS04060
uniprot id: B4RG37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS19330
gene id: 450851:PHZ_RS19330
uniprot id: B4RCX6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

450851:PHZ RS04155
gene id: 450851:PHZ_RS04155
uniprot id: B4RG55
names: Similarity
messages: Belongs to the Nudix hydrolase family.

450851:PHZ RS06520
gene id: 450851:PHZ_RS06520
uniprot id: B4R8G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS02110
gene id: 450851:PHZ_RS02110
uniprot id: B4RDV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

450851:PHZ RS19140
gene id: 450851:PHZ_RS19140
uniprot id: B4RC79
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

450851:PHZ RS18895
gene id: 450851:PHZ_RS18895
uniprot id: B4RC31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS00610
gene id: 450851:PHZ_RS00610
uniprot id: B4RCC8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

450851:PHZ RS04580
gene id: 450851:PHZ_RS04580
uniprot id: B4RGD1
names: Similarity
messages: Belongs to the aspartokinase family.

450851:PHZ RS23160
gene id: 450851:PHZ_RS23160
uniprot id: B4RGM4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS17680
gene id: 450851:PHZ_RS17680
uniprot id: B4RAK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

450851:PHZ RS20045
gene id: 450851:PHZ_RS20045
uniprot id: B4RI58
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

450851:PHZ RS02735
gene id: 450851:PHZ_RS02735
uniprot id: B4REH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

450851:PHZ RS06485
gene id: 450851:PHZ_RS06485
uniprot id: B4R8G0
names: Similarity
messages: Belongs to the virb1 family.

450851:PHZ RS09780
gene id: 450851:PHZ_RS09780
uniprot id: B4RBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

450851:PHZ RS07715
gene id: 450851:PHZ_RS07715
uniprot id: B4R9Q4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS15260
gene id: 450851:PHZ_RS15260
uniprot id: B4R845
names: Similarity
messages: Belongs to the AHA1 family.

450851:PHZ RS17585
gene id: 450851:PHZ_RS17585
uniprot id: B4RA79
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS05850
gene id: 450851:PHZ_RS05850
uniprot id: B4R7U6
names: Similarity
messages: Belongs to the UPF0758 family.

450851:PHZ RS07280
gene id: 450851:PHZ_RS07280
uniprot id: B4R966
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

450851:PHZ RS05620
gene id: 450851:PHZ_RS05620
uniprot id: B4RHI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

450851:PHZ RS05070
gene id: 450851:PHZ_RS05070
uniprot id: B4RGX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

450851:PHZ RS06405
gene id: 450851:PHZ_RS06405
uniprot id: B4R839
names: Similarity
messages: Belongs to the pirin family.

450851:PHZ RS00560
gene id: 450851:PHZ_RS00560
uniprot id: B4RCB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS09480
gene id: 450851:PHZ_RS09480
uniprot id: B4RBT3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

450851:PHZ RS08590
gene id: 450851:PHZ_RS08590
uniprot id: B4RAG3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

450851:PHZ RS14895
gene id: 450851:PHZ_RS14895
uniprot id: B4RHQ4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

450851:PHZ RS12635
gene id: 450851:PHZ_RS12635
uniprot id: B4RFC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

450851:PHZ RS20595
gene id: 450851:PHZ_RS20595
uniprot id: B4RIG0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

450851:PHZ RS20070
gene id: 450851:PHZ_RS20070
uniprot id: B4RI63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

450851:PHZ RS13240
gene id: 450851:PHZ_RS13240
uniprot id: B4RFY5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

450851:PHZ RS09770
gene id: 450851:PHZ_RS09770
uniprot id: B4RBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

450851:PHZ RS10705
gene id: 450851:PHZ_RS10705
uniprot id: B4RDG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

450851:PHZ RS09650
gene id: 450851:PHZ_RS09650
uniprot id: B4RBW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

450851:PHZ RS17125
gene id: 450851:PHZ_RS17125
uniprot id: B4R9Z1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

450851:PHZ RS17365
gene id: 450851:PHZ_RS17365
uniprot id: B4RA36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

450851:PHZ RS16300
gene id: 450851:PHZ_RS16300
uniprot id: B4R8Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

450851:PHZ RS18440
gene id: 450851:PHZ_RS18440
uniprot id: B4RB97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

450851:PHZ RS00650
gene id: 450851:PHZ_RS00650
uniprot id: B4RCD6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

450851:PHZ RS16430
gene id: 450851:PHZ_RS16430
uniprot id: B4R905
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

450851:PHZ RS00895
gene id: 450851:PHZ_RS00895
uniprot id: B4RCI1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

450851:PHZ RS19095
gene id: 450851:PHZ_RS19095
uniprot id: B4RC70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

450851:PHZ RS04375
gene id: 450851:PHZ_RS04375
uniprot id: B4RG92
names: Similarity
messages: Belongs to the oxoprolinase family.

450851:PHZ RS17655
gene id: 450851:PHZ_RS17655
uniprot id: B4RAJ7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

450851:PHZ RS00620
gene id: 450851:PHZ_RS00620
uniprot id: B4RCD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

450851:PHZ RS19040
gene id: 450851:PHZ_RS19040
uniprot id: B4RC59
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS09215
gene id: 450851:PHZ_RS09215
uniprot id: B4RB29
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

450851:PHZ RS14855
gene id: 450851:PHZ_RS14855
uniprot id: B4RHP7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS04575
gene id: 450851:PHZ_RS04575
uniprot id: B4RGD0
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS16425
gene id: 450851:PHZ_RS16425
uniprot id: B4R904
names: Similarity
messages: Belongs to the phosphohexose mutase family.

450851:PHZ RS11015
gene id: 450851:PHZ_RS11015
uniprot id: B4RDY4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS04855
gene id: 450851:PHZ_RS04855
uniprot id: B4RGT7
names: Similarity
messages: Belongs to the thioesterase PaaI family.

450851:PHZ RS09075
gene id: 450851:PHZ_RS09075
uniprot id: B4RB03
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

450851:PHZ RS17015
gene id: 450851:PHZ_RS17015
uniprot id: B4R9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS19225
gene id: 450851:PHZ_RS19225
uniprot id: B4RC95
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

450851:PHZ RS07185
gene id: 450851:PHZ_RS07185
uniprot id: B4R947
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

450851:PHZ RS05985
gene id: 450851:PHZ_RS05985
uniprot id: B4R7X1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS03565
gene id: 450851:PHZ_RS03565
uniprot id: B4RFJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS07050
gene id: 450851:PHZ_RS07050
uniprot id: B4R921
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

450851:PHZ RS11220
gene id: 450851:PHZ_RS11220
uniprot id: B4RE23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS14915
gene id: 450851:PHZ_RS14915
uniprot id: B4RHQ8
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

450851:PHZ RS14095
gene id: 450851:PHZ_RS14095
uniprot id: B4RH10
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS19715
gene id: 450851:PHZ_RS19715
uniprot id: B4RI00
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

450851:PHZ RS09935
gene id: 450851:PHZ_RS09935
uniprot id: B4RCM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

450851:PHZ RS00195
gene id: 450851:PHZ_RS00195
uniprot id: B4RBJ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

450851:PHZ RS00695
gene id: 450851:PHZ_RS00695
uniprot id: B4RCE4
names: Similarity
messages: Belongs to the Gfa family.

450851:PHZ RS06785
gene id: 450851:PHZ_RS06785
uniprot id: B4R8L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

450851:PHZ RS06435
gene id: 450851:PHZ_RS06435
uniprot id: B4R8F1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

450851:PHZ RS08965
gene id: 450851:PHZ_RS08965
uniprot id: B4RAY5
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

450851:PHZ RS04670
gene id: 450851:PHZ_RS04670
uniprot id: B4RGQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm
messages: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.

450851:PHZ RS18995
gene id: 450851:PHZ_RS18995
uniprot id: B4RC50
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

450851:PHZ RS01275
gene id: 450851:PHZ_RS01275
uniprot id: B4RD38
names: Similarity
messages: Belongs to the SCO1/2 family.

450851:PHZ RS06780
gene id: 450851:PHZ_RS06780
uniprot id: B4R8L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

450851:PHZ RS09970
gene id: 450851:PHZ_RS09970
uniprot id: B4RCN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

450851:PHZ RS18655
gene id: 450851:PHZ_RS18655
uniprot id: B4RBD4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

450851:PHZ RS05795
gene id: 450851:PHZ_RS05795
uniprot id: B4RHL0
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS06795
gene id: 450851:PHZ_RS06795
uniprot id: B4R8J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

450851:PHZ RS00340
gene id: 450851:PHZ_RS00340
uniprot id: B4RBL4
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

450851:PHZ RS05570
gene id: 450851:PHZ_RS05570
uniprot id: B4RHH3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

450851:PHZ RS02475
gene id: 450851:PHZ_RS02475
uniprot id: B4REC9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

450851:PHZ RS20075
gene id: 450851:PHZ_RS20075
uniprot id: B4RI64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

450851:PHZ RS09850
gene id: 450851:PHZ_RS09850
uniprot id: B4RC03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS21250
gene id: 450851:PHZ_RS21250
uniprot id: B4RIS8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS06995
gene id: 450851:PHZ_RS06995
uniprot id: B4R911
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

450851:PHZ RS02585
gene id: 450851:PHZ_RS02585
uniprot id: B4REE9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

450851:PHZ RS08735
gene id: 450851:PHZ_RS08735
uniprot id: B4RAU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

450851:PHZ RS10140
gene id: 450851:PHZ_RS10140
uniprot id: B4RCR4
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

450851:PHZ RS09695
gene id: 450851:PHZ_RS09695
uniprot id: B4RBX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

450851:PHZ RS10980
gene id: 450851:PHZ_RS10980
uniprot id: B4RDM1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS01585
gene id: 450851:PHZ_RS01585
uniprot id: B4RD99
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS12350
gene id: 450851:PHZ_RS12350
uniprot id: B4RF73
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

450851:PHZ RS07225
gene id: 450851:PHZ_RS07225
uniprot id: B4R955
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

450851:PHZ RS08605
gene id: 450851:PHZ_RS08605
uniprot id: B4RAG6
names: Similarity
messages: Belongs to the YicC/YloC family.

450851:PHZ RS14710
gene id: 450851:PHZ_RS14710
uniprot id: B4RHM2
names: Similarity
messages: Belongs to the peptidase C56 family.

450851:PHZ RS01320
gene id: 450851:PHZ_RS01320
uniprot id: B4RD47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

450851:PHZ RS03685
gene id: 450851:PHZ_RS03685
uniprot id: B4RFL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

450851:PHZ RS01310
gene id: 450851:PHZ_RS01310
uniprot id: B4RD45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

450851:PHZ RS06475
gene id: 450851:PHZ_RS06475
uniprot id: B4R8F8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS20225
gene id: 450851:PHZ_RS20225
uniprot id: B4RI89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

450851:PHZ RS12850
gene id: 450851:PHZ_RS12850
uniprot id: B4RFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

450851:PHZ RS04180
gene id: 450851:PHZ_RS04180
uniprot id: B4RG60
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

450851:PHZ RS09120
gene id: 450851:PHZ_RS09120
uniprot id: B4RB12
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

450851:PHZ RS10820
gene id: 450851:PHZ_RS10820
uniprot id: B4RDJ0
names: Similarity
messages: Belongs to the HesB/IscA family.

450851:PHZ RS19130
gene id: 450851:PHZ_RS19130
uniprot id: B4RC77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

450851:PHZ RS00730
gene id: 450851:PHZ_RS00730
uniprot id: B4RCF0
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

450851:PHZ RS06615
gene id: 450851:PHZ_RS06615
uniprot id: B4R8I3
names: Subcellular Location Annotation
messages: Cytoplasm

450851:PHZ RS12660
gene id: 450851:PHZ_RS12660
uniprot id: B4RFC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

450851:PHZ RS03210
gene id: 450851:PHZ_RS03210
uniprot id: B4RF20
names: Similarity
messages: Belongs to the cytochrome P450 family.

450851:PHZ RS12915
gene id: 450851:PHZ_RS12915
uniprot id: B4RFT2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS20055
gene id: 450851:PHZ_RS20055
uniprot id: B4RI60
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

450851:PHZ RS08665
gene id: 450851:PHZ_RS08665
uniprot id: B4RAH7
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

450851:PHZ RS03935
gene id: 450851:PHZ_RS03935
uniprot id: B4RFQ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

450851:PHZ RS19020
gene id: 450851:PHZ_RS19020
uniprot id: B4RC55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

450851:PHZ RS17730
gene id: 450851:PHZ_RS17730
uniprot id: B4RAL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

450851:PHZ RS00885
gene id: 450851:PHZ_RS00885
uniprot id: B4RCH9
names: Similarity
messages: Belongs to the glutamate synthase family.

450851:PHZ RS09995
gene id: 450851:PHZ_RS09995
uniprot id: B4RCN8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

450851:PHZ RS09605
gene id: 450851:PHZ_RS09605
uniprot id: B4RBV7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

450851:PHZ RS05295
gene id: 450851:PHZ_RS05295
uniprot id: B4RHC5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

450851:PHZ RS19055
gene id: 450851:PHZ_RS19055
uniprot id: B4RC62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

450851:PHZ RS04115
gene id: 450851:PHZ_RS04115
uniprot id: B4RG47
names: Similarity
messages: Belongs to the FMO family.

450851:PHZ RS10300
gene id: 450851:PHZ_RS10300
uniprot id: B4RCU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

450851:PHZ RS19695
gene id: 450851:PHZ_RS19695
uniprot id: B4RHZ7
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS13975
gene id: 450851:PHZ_RS13975
uniprot id: B4RGM8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

450851:PHZ RS16755
gene id: 450851:PHZ_RS16755
uniprot id: B4R9H2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS00580
gene id: 450851:PHZ_RS00580
uniprot id: B4RCC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

450851:PHZ RS11770
gene id: 450851:PHZ_RS11770
uniprot id: B4REM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

450851:PHZ RS01600
gene id: 450851:PHZ_RS01600
uniprot id: B4RDA2
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

450851:PHZ RS20800
gene id: 450851:PHZ_RS20800
uniprot id: B4RHY5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

450851:PHZ RS00910
gene id: 450851:PHZ_RS00910
uniprot id: B4RCI3
names: Similarity
messages: Belongs to the cytochrome P450 family.

450851:PHZ RS12600
gene id: 450851:PHZ_RS12600
uniprot id: B4RFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

450851:PHZ RS20780
gene id: 450851:PHZ_RS20780
uniprot id: B4RIJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Periplasm

450851:PHZ RS01070
gene id: 450851:PHZ_RS01070
uniprot id: B4RCL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

450851:PHZ RS09645
gene id: 450851:PHZ_RS09645
uniprot id: B4RBW5
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

450851:PHZ RS01140
gene id: 450851:PHZ_RS01140
uniprot id: B4RD19
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS02910
gene id: 450851:PHZ_RS02910
uniprot id: B4REW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

450851:PHZ RS20365
gene id: 450851:PHZ_RS20365
uniprot id: B4RIB5
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS08740
gene id: 450851:PHZ_RS08740
uniprot id: B4RAU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

450851:PHZ RS04135
gene id: 450851:PHZ_RS04135
uniprot id: B4RG51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS07395
gene id: 450851:PHZ_RS07395
uniprot id: B4R986
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

450851:PHZ RS07895
gene id: 450851:PHZ_RS07895
uniprot id: B4R9T5
names: Similarity
messages: Belongs to the ArsC family.

450851:PHZ RS20495
gene id: 450851:PHZ_RS20495
uniprot id: B4RIE1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS17685
gene id: 450851:PHZ_RS17685
uniprot id: B4RAK2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

450851:PHZ RS17200
gene id: 450851:PHZ_RS17200
uniprot id: B4RA06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

450851:PHZ RS18280
gene id: 450851:PHZ_RS18280
uniprot id: B4RB66
names: Function
messages: Multidrug efflux pump.

450851:PHZ RS03250
gene id: 450851:PHZ_RS03250
uniprot id: B4RF28
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

450851:PHZ RS05575
gene id: 450851:PHZ_RS05575
uniprot id: B4RHH4
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS10400
gene id: 450851:PHZ_RS10400
uniprot id: B4RCW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

450851:PHZ RS10770
gene id: 450851:PHZ_RS10770
uniprot id: B4RDI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

450851:PHZ RS09245
gene id: 450851:PHZ_RS09245
uniprot id: B4RB34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

450851:PHZ RS05390
gene id: 450851:PHZ_RS05390
uniprot id: B4RHD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

450851:PHZ RS09320
gene id: 450851:PHZ_RS09320
uniprot id: B4RBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

450851:PHZ RS12085
gene id: 450851:PHZ_RS12085
uniprot id: B4RET2
names: Similarity
messages: Belongs to the UPF0262 family.

450851:PHZ RS17725
gene id: 450851:PHZ_RS17725
uniprot id: B4RAK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS10225
gene id: 450851:PHZ_RS10225
uniprot id: B4RCT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS09875
gene id: 450851:PHZ_RS09875
uniprot id: B4RCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

450851:PHZ RS17995
gene id: 450851:PHZ_RS17995
uniprot id: B4RAQ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS11780
gene id: 450851:PHZ_RS11780
uniprot id: B4REN0
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS00345
gene id: 450851:PHZ_RS00345
uniprot id: B4RBL5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

450851:PHZ RS10745
gene id: 450851:PHZ_RS10745
uniprot id: B4RDH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

450851:PHZ RS18010
gene id: 450851:PHZ_RS18010
uniprot id: B4RAR1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

450851:PHZ RS02100
gene id: 450851:PHZ_RS02100
uniprot id: B4RDU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

450851:PHZ RS15395
gene id: 450851:PHZ_RS15395
uniprot id: B4R869
names: Similarity
messages: Belongs to the Gfa family.

450851:PHZ RS12385
gene id: 450851:PHZ_RS12385
uniprot id: B4RF80
names: Similarity
messages: Belongs to the group II decarboxylase family.

450851:PHZ RS15870
gene id: 450851:PHZ_RS15870
uniprot id: B4R8Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

450851:PHZ RS00670
gene id: 450851:PHZ_RS00670
uniprot id: B4RCD9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS02120
gene id: 450851:PHZ_RS02120
uniprot id: B4RDV3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS17635
gene id: 450851:PHZ_RS17635
uniprot id: B4RAJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

450851:PHZ RS16660
gene id: 450851:PHZ_RS16660
uniprot id: B4R9F3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

450851:PHZ RS10660
gene id: 450851:PHZ_RS10660
uniprot id: B4RDG0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

450851:PHZ RS18545
gene id: 450851:PHZ_RS18545
uniprot id: B4RBB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

450851:PHZ RS05005
gene id: 450851:PHZ_RS05005
uniprot id: B4RGW4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

450851:PHZ RS03030
gene id: 450851:PHZ_RS03030
uniprot id: B4REY7
names: Similarity
messages: Belongs to the UPF0246 family.

450851:PHZ RS02520
gene id: 450851:PHZ_RS02520
uniprot id: B4RED7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

450851:PHZ RS12460
gene id: 450851:PHZ_RS12460
uniprot id: B4RF92
names: Similarity
messages: Belongs to the sulfatase family.

450851:PHZ RS18855
gene id: 450851:PHZ_RS18855
uniprot id: B4RC23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

450851:PHZ RS19535
gene id: 450851:PHZ_RS19535
uniprot id: B4RHX1
names: Similarity
messages: Belongs to the ParB family.

450851:PHZ RS18675
gene id: 450851:PHZ_RS18675
uniprot id: B4RBD8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

450851:PHZ RS05995
gene id: 450851:PHZ_RS05995
uniprot id: B4R7X3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

450851:PHZ RS02945
gene id: 450851:PHZ_RS02945
uniprot id: B4REX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

450851:PHZ RS01365
gene id: 450851:PHZ_RS01365
uniprot id: B4RD56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

450851:PHZ RS02260
gene id: 450851:PHZ_RS02260
uniprot id: B4RDY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS07785
gene id: 450851:PHZ_RS07785
uniprot id: B4R9R7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

450851:PHZ RS06110
gene id: 450851:PHZ_RS06110
uniprot id: B4R7Z3
names: Similarity
messages: Belongs to the peptidase M16 family.

450851:PHZ RS05245
gene id: 450851:PHZ_RS05245
uniprot id: B4RHB5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

450851:PHZ RS18590
gene id: 450851:PHZ_RS18590
uniprot id: B4RBC5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

450851:PHZ RS09030
gene id: 450851:PHZ_RS09030
uniprot id: B4RAZ7
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

450851:PHZ RS10005
gene id: 450851:PHZ_RS10005
uniprot id: B4RCP0
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

450851:PHZ RS05780
gene id: 450851:PHZ_RS05780
uniprot id: B4RHK8
names: Similarity
messages: Belongs to the FrmR/RcnR family.

450851:PHZ RS00810
gene id: 450851:PHZ_RS00810
uniprot id: B4RCG5
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

450851:PHZ RS02330
gene id: 450851:PHZ_RS02330
uniprot id: B4REA3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

450851:PHZ RS09010
gene id: 450851:PHZ_RS09010
uniprot id: B4RAZ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

450851:PHZ RS10675
gene id: 450851:PHZ_RS10675
uniprot id: B4RDG3
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS19340
gene id: 450851:PHZ_RS19340
uniprot id: B4RCX8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

450851:PHZ RS09715
gene id: 450851:PHZ_RS09715
uniprot id: B4RBX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

450851:PHZ RS04335
gene id: 450851:PHZ_RS04335
uniprot id: B4RG86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

450851:PHZ RS12575
gene id: 450851:PHZ_RS12575
uniprot id: B4RFB3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS18000
gene id: 450851:PHZ_RS18000
uniprot id: B4RAR0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS10750
gene id: 450851:PHZ_RS10750
uniprot id: B4RDH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

450851:PHZ RS10115
gene id: 450851:PHZ_RS10115
uniprot id: B4RCQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS18015
gene id: 450851:PHZ_RS18015
uniprot id: B4RAR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

450851:PHZ RS12755
gene id: 450851:PHZ_RS12755
uniprot id: B4RFE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

450851:PHZ RS04205
gene id: 450851:PHZ_RS04205
uniprot id: B4RG64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

450851:PHZ RS08155
gene id: 450851:PHZ_RS08155
uniprot id: B4RA88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS17540
gene id: 450851:PHZ_RS17540
uniprot id: B4RA70
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

450851:PHZ RS07260
gene id: 450851:PHZ_RS07260
uniprot id: B4R962
names: Similarity
messages: Belongs to the DprA/Smf family.

450851:PHZ RS20105
gene id: 450851:PHZ_RS20105
uniprot id: B4RI69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

450851:PHZ RS03020
gene id: 450851:PHZ_RS03020
uniprot id: B4REY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

450851:PHZ RS19210
gene id: 450851:PHZ_RS19210
uniprot id: B4RC92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

450851:PHZ RS02765
gene id: 450851:PHZ_RS02765
uniprot id: B4REI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

450851:PHZ RS06080
gene id: 450851:PHZ_RS06080
uniprot id: B4R7Y7
names: Similarity
messages: Belongs to the PhoH family.

450851:PHZ RS01315
gene id: 450851:PHZ_RS01315
uniprot id: B4RD46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

450851:PHZ RS09795
gene id: 450851:PHZ_RS09795
uniprot id: B4RBZ4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

450851:PHZ RS01410
gene id: 450851:PHZ_RS01410
uniprot id: B4RD65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

450851:PHZ RS00155
gene id: 450851:PHZ_RS00155
uniprot id: B4RBI2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

450851:PHZ RS10720
gene id: 450851:PHZ_RS10720
uniprot id: B4RDH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

450851:PHZ RS09575
gene id: 450851:PHZ_RS09575
uniprot id: B4RBV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

450851:PHZ RS06790
gene id: 450851:PHZ_RS06790
uniprot id: B4R8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

450851:PHZ RS12045
gene id: 450851:PHZ_RS12045
uniprot id: B4RES6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

450851:PHZ RS08835
gene id: 450851:PHZ_RS08835
uniprot id: B4RAW1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS12615
gene id: 450851:PHZ_RS12615
uniprot id: B4RFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

450851:PHZ RS09315
gene id: 450851:PHZ_RS09315
uniprot id: B4RBQ1
names: Similarity
messages: Belongs to the MotB family.

450851:PHZ RS07180
gene id: 450851:PHZ_RS07180
uniprot id: B4R946
names: Similarity
messages: Belongs to the ClpA/ClpB family.

450851:PHZ RS05415
gene id: 450851:PHZ_RS05415
uniprot id: B4RHE4
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

450851:PHZ RS10855
gene id: 450851:PHZ_RS10855
uniprot id: B4RDJ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS05885
gene id: 450851:PHZ_RS05885
uniprot id: B4R7V3
names: Similarity
messages: Belongs to the SfsA family.

450851:PHZ RS07880
gene id: 450851:PHZ_RS07880
uniprot id: B4R9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

450851:PHZ RS15095
gene id: 450851:PHZ_RS15095
uniprot id: B4RHU3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

450851:PHZ RS18200
gene id: 450851:PHZ_RS18200
uniprot id: B4RB50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS09115
gene id: 450851:PHZ_RS09115
uniprot id: B4RB11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

450851:PHZ RS12820
gene id: 450851:PHZ_RS12820
uniprot id: B4RFF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

450851:PHZ RS07740
gene id: 450851:PHZ_RS07740
uniprot id: B4R9Q8
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS04955
gene id: 450851:PHZ_RS04955
uniprot id: B4RGV5
names: Similarity
messages: Belongs to the histone deacetylase family.

450851:PHZ RS11110
gene id: 450851:PHZ_RS11110
uniprot id: B4RE03
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

450851:PHZ RS10110
gene id: 450851:PHZ_RS10110
uniprot id: B4RCQ8
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

450851:PHZ RS18450
gene id: 450851:PHZ_RS18450
uniprot id: B4RB99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

450851:PHZ RS09060
gene id: 450851:PHZ_RS09060
uniprot id: B4RB00
names: Similarity
messages: Belongs to the RecJ family.

450851:PHZ RS06745
gene id: 450851:PHZ_RS06745
uniprot id: B4R8K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

450851:PHZ RS15625
gene id: 450851:PHZ_RS15625
uniprot id: B4R8A9
names: Similarity
messages: Belongs to the OmpW/AlkL family.

450851:PHZ RS09740
gene id: 450851:PHZ_RS09740
uniprot id: B4RBY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

450851:PHZ RS05930
gene id: 450851:PHZ_RS05930
uniprot id: B4R7W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

450851:PHZ RS03240
gene id: 450851:PHZ_RS03240
uniprot id: B4RF26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

450851:PHZ RS06530
gene id: 450851:PHZ_RS06530
uniprot id: B4R8G9
names: Similarity
messages: Belongs to the FGGY kinase family.

450851:PHZ RS04800
gene id: 450851:PHZ_RS04800
uniprot id: B4RGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

450851:PHZ RS16435
gene id: 450851:PHZ_RS16435
uniprot id: B4R906
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

450851:PHZ RS04640
gene id: 450851:PHZ_RS04640
uniprot id: B4RGP6
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS19300
gene id: 450851:PHZ_RS19300
uniprot id: B4RCB0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS18365
gene id: 450851:PHZ_RS18365
uniprot id: B4RB83
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

450851:PHZ RS02265
gene id: 450851:PHZ_RS02265
uniprot id: B4RE89
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

450851:PHZ RS03550
gene id: 450851:PHZ_RS03550
uniprot id: B4RFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS02565
gene id: 450851:PHZ_RS02565
uniprot id: B4REE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS06650
gene id: 450851:PHZ_RS06650
uniprot id: B4R8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

450851:PHZ RS09290
gene id: 450851:PHZ_RS09290
uniprot id: B4RB42
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

450851:PHZ RS09405
gene id: 450851:PHZ_RS09405
uniprot id: B4RBR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

450851:PHZ RS08945
gene id: 450851:PHZ_RS08945
uniprot id: B4RAY1
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

450851:PHZ RS13040
gene id: 450851:PHZ_RS13040
uniprot id: B4RFV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

450851:PHZ RS19730
gene id: 450851:PHZ_RS19730
uniprot id: B4RI02
names: Similarity
messages: Belongs to the thioredoxin family.

450851:PHZ RS08065
gene id: 450851:PHZ_RS08065
uniprot id: B4R9W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS14965
gene id: 450851:PHZ_RS14965
uniprot id: B4RHR8
names: Similarity
messages: Belongs to the UPF0260 family.

450851:PHZ RS16485
gene id: 450851:PHZ_RS16485
uniprot id: B4R9C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

450851:PHZ RS01045
gene id: 450851:PHZ_RS01045
uniprot id: B4RCK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

450851:PHZ RS14835
gene id: 450851:PHZ_RS14835
uniprot id: B4RHP4
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

450851:PHZ RS03180
gene id: 450851:PHZ_RS03180
uniprot id: B4RF16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

450851:PHZ RS08120
gene id: 450851:PHZ_RS08120
uniprot id: B4R9X4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

450851:PHZ RS20870
gene id: 450851:PHZ_RS20870
uniprot id: B4RIL0
names: Similarity
messages: Belongs to the UPF0166 family.

450851:PHZ RS13315
gene id: 450851:PHZ_RS13315
uniprot id: B4RFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS13155
gene id: 450851:PHZ_RS13155
uniprot id: B4RFX3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS13610
gene id: 450851:PHZ_RS13610
uniprot id: B4RGF5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

450851:PHZ RS05375
gene id: 450851:PHZ_RS05375
uniprot id: B4RHD7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

450851:PHZ RS01775
gene id: 450851:PHZ_RS01775
uniprot id: B4RDN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS02770
gene id: 450851:PHZ_RS02770
uniprot id: B4REI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

450851:PHZ RS02230
gene id: 450851:PHZ_RS02230
uniprot id: B4RDX5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

450851:PHZ RS14620
gene id: 450851:PHZ_RS14620
uniprot id: B4RH97
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS16640
gene id: 450851:PHZ_RS16640
uniprot id: B4R9E9
names: Similarity
messages: Belongs to the GSP E family.

450851:PHZ RS11765
gene id: 450851:PHZ_RS11765
uniprot id: B4REM7
names: Similarity
messages: Belongs to the universal stress protein A family.

450851:PHZ RS07090
gene id: 450851:PHZ_RS07090
uniprot id: B4R928
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS01065
gene id: 450851:PHZ_RS01065
uniprot id: B4RCL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

450851:PHZ RS15370
gene id: 450851:PHZ_RS15370
uniprot id: B4R864
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS20220
gene id: 450851:PHZ_RS20220
uniprot id: B4RI88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

450851:PHZ RS00825
gene id: 450851:PHZ_RS00825
uniprot id: B4RCG7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

450851:PHZ RS06755
gene id: 450851:PHZ_RS06755
uniprot id: B4R8K6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

450851:PHZ RS02300
gene id: 450851:PHZ_RS02300
uniprot id: B4RE97
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

450851:PHZ RS04430
gene id: 450851:PHZ_RS04430
uniprot id: B4RGA3
names: Similarity
messages: Belongs to the cytochrome P450 family.

450851:PHZ RS18990
gene id: 450851:PHZ_RS18990
uniprot id: B4RC49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

450851:PHZ RS01700
gene id: 450851:PHZ_RS01700
uniprot id: B4RDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

450851:PHZ RS10630
gene id: 450851:PHZ_RS10630
uniprot id: B4RDF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

450851:PHZ RS00625
gene id: 450851:PHZ_RS00625
uniprot id: B4RCD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

450851:PHZ RS10295
gene id: 450851:PHZ_RS10295
uniprot id: B4RCU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

450851:PHZ RS15540
gene id: 450851:PHZ_RS15540
uniprot id: B4R893
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

450851:PHZ RS00235
gene id: 450851:PHZ_RS00235
uniprot id: B4RBJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

450851:PHZ RS18130
gene id: 450851:PHZ_RS18130
uniprot id: B4RAT3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

450851:PHZ RS12070
gene id: 450851:PHZ_RS12070
uniprot id: B4RES9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

450851:PHZ RS00530
gene id: 450851:PHZ_RS00530
uniprot id: B4RCB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

450851:PHZ RS16170
gene id: 450851:PHZ_RS16170
uniprot id: B4R8V7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

450851:PHZ RS09865
gene id: 450851:PHZ_RS09865
uniprot id: B4RC06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

450851:PHZ RS01470
gene id: 450851:PHZ_RS01470
uniprot id: B4RD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS13015
gene id: 450851:PHZ_RS13015
uniprot id: B4RFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

450851:PHZ RS12480
gene id: 450851:PHZ_RS12480
uniprot id: B4RF95
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

450851:PHZ RS16535
gene id: 450851:PHZ_RS16535
uniprot id: B4R9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

450851:PHZ RS01735
gene id: 450851:PHZ_RS01735
uniprot id: B4RDN0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

450851:PHZ RS07080
gene id: 450851:PHZ_RS07080
uniprot id: B4R926
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

450851:PHZ RS09735
gene id: 450851:PHZ_RS09735
uniprot id: B4RBY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

450851:PHZ RS10710
gene id: 450851:PHZ_RS10710
uniprot id: B4RDG8
names: Similarity
messages: Belongs to the GST superfamily.

450851:PHZ RS16725
gene id: 450851:PHZ_RS16725
uniprot id: B4R9G6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

450851:PHZ RS15125
gene id: 450851:PHZ_RS15125
uniprot id: B4RHU7
names: Similarity
messages: Belongs to the peptidase S49 family.

450851:PHZ RS07320
gene id: 450851:PHZ_RS07320
uniprot id: B4R973
names: Similarity
messages: Belongs to the Gfa family.

450851:PHZ RS06930
gene id: 450851:PHZ_RS06930
uniprot id: B4R8P1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

450851:PHZ RS16680
gene id: 450851:PHZ_RS16680
uniprot id: B4R9F7
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.

450851:PHZ RS15210
gene id: 450851:PHZ_RS15210
uniprot id: B4RHW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS14055
gene id: 450851:PHZ_RS14055
uniprot id: B4RH02
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS19500
gene id: 450851:PHZ_RS19500
uniprot id: B4RD08
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS10330
gene id: 450851:PHZ_RS10330
uniprot id: B4RCV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

450851:PHZ RS21125
gene id: 450851:PHZ_RS21125
uniprot id: B4RIQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

450851:PHZ RS17795
gene id: 450851:PHZ_RS17795
uniprot id: B4RAM3
names: Similarity
messages: Belongs to the malate synthase family.

450851:PHZ RS08005
gene id: 450851:PHZ_RS08005
uniprot id: B4R9V4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

450851:PHZ RS03630
gene id: 450851:PHZ_RS03630
uniprot id: B4RFK2
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS10965
gene id: 450851:PHZ_RS10965
uniprot id: B4RDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

450851:PHZ RS06820
gene id: 450851:PHZ_RS06820
uniprot id: B4R8L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

450851:PHZ RS06905
gene id: 450851:PHZ_RS06905
uniprot id: B4R8N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

450851:PHZ RS19090
gene id: 450851:PHZ_RS19090
uniprot id: B4RC69
names: Similarity
messages: Belongs to the PhoH family.

450851:PHZ RS12880
gene id: 450851:PHZ_RS12880
uniprot id: B4RFS5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS06815
gene id: 450851:PHZ_RS06815
uniprot id: B4R8L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

450851:PHZ RS14035
gene id: 450851:PHZ_RS14035
uniprot id: B4RGP0
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2R)-3-phosphoglycerate (3PG) as 3-[(R)-glyceryl]-diphospho-5'-guanosine, via the condensation of 3PG with GTP. It is involved in the biosynthesis of a derivative of the hydride carrier cofactor coenzyme F420, 3PG-F420.

450851:PHZ RS06750
gene id: 450851:PHZ_RS06750
uniprot id: B4R8K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

450851:PHZ RS02895
gene id: 450851:PHZ_RS02895
uniprot id: B4REW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

450851:PHZ RS08000
gene id: 450851:PHZ_RS08000
uniprot id: B4R9V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

450851:PHZ RS20240
gene id: 450851:PHZ_RS20240
uniprot id: B4RI92
names: Similarity
messages: Belongs to the universal stress protein A family.

450851:PHZ RS04450
gene id: 450851:PHZ_RS04450
uniprot id: B4RGA7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

450851:PHZ RS11900
gene id: 450851:PHZ_RS11900
uniprot id: B4REQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

450851:PHZ RS04555
gene id: 450851:PHZ_RS04555
uniprot id: B4RGC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

450851:PHZ RS07710
gene id: 450851:PHZ_RS07710
uniprot id: B4R9Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

450851:PHZ RS05920
gene id: 450851:PHZ_RS05920
uniprot id: B4R7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS13070
gene id: 450851:PHZ_RS13070
uniprot id: B4RFV9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS00555
gene id: 450851:PHZ_RS00555
uniprot id: B4RCB8
names: Subcellular Location Annotation
messages: Nucleus

450851:PHZ RS18685
gene id: 450851:PHZ_RS18685
uniprot id: B4RBE0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

450851:PHZ RS10615
gene id: 450851:PHZ_RS10615
uniprot id: B4RDF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS19785
gene id: 450851:PHZ_RS19785
uniprot id: B4RI10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

450851:PHZ RS14695
gene id: 450851:PHZ_RS14695
uniprot id: B4RHL9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

450851:PHZ RS19425
gene id: 450851:PHZ_RS19425
uniprot id: B4RCZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

450851:PHZ RS01640
gene id: 450851:PHZ_RS01640
uniprot id: B4RDA9
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

450851:PHZ RS13725
gene id: 450851:PHZ_RS13725
uniprot id: B4RGH9
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).

450851:PHZ RS16270
gene id: 450851:PHZ_RS16270
uniprot id: B4R8X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

450851:PHZ RS02535
gene id: 450851:PHZ_RS02535
uniprot id: B4REE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

450851:PHZ RS13650
gene id: 450851:PHZ_RS13650
uniprot id: B4RGG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS02645
gene id: 450851:PHZ_RS02645
uniprot id: B4REG0
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS15730
gene id: 450851:PHZ_RS15730
uniprot id: B4R8C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

450851:PHZ RS01530
gene id: 450851:PHZ_RS01530
uniprot id: B4RD88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

450851:PHZ RS08765
gene id: 450851:PHZ_RS08765
uniprot id: B4RAV1
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

450851:PHZ RS07000
gene id: 450851:PHZ_RS07000
uniprot id: B4R912
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

450851:PHZ RS19850
gene id: 450851:PHZ_RS19850
uniprot id: B4RI23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

450851:PHZ RS17625
gene id: 450851:PHZ_RS17625
uniprot id: B4RAJ1
names: Similarity
messages: Belongs to the CFA/CMAS family.

450851:PHZ RS18355
gene id: 450851:PHZ_RS18355
uniprot id: B4RB81
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

450851:PHZ RS13845
gene id: 450851:PHZ_RS13845
uniprot id: B4RGK2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS17700
gene id: 450851:PHZ_RS17700
uniprot id: B4RAK5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

450851:PHZ RS19805
gene id: 450851:PHZ_RS19805
uniprot id: B4RI14
names: Similarity
messages: Belongs to the universal stress protein A family.

450851:PHZ RS10780
gene id: 450851:PHZ_RS10780
uniprot id: B4RDI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

450851:PHZ RS04970
gene id: 450851:PHZ_RS04970
uniprot id: B4RGV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

450851:PHZ RS12220
gene id: 450851:PHZ_RS12220
uniprot id: B4RF58
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

450851:PHZ RS17340
gene id: 450851:PHZ_RS17340
uniprot id: B4RA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS19570
gene id: 450851:PHZ_RS19570
uniprot id: B4RHX8
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

450851:PHZ RS15755
gene id: 450851:PHZ_RS15755
uniprot id: B4R8D1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

450851:PHZ RS00590
gene id: 450851:PHZ_RS00590
uniprot id: B4RCC4
names: Similarity
messages: Belongs to the Gfa family.

450851:PHZ RS20855
gene id: 450851:PHZ_RS20855
uniprot id: B4RIK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

450851:PHZ RS13085
gene id: 450851:PHZ_RS13085
uniprot id: B4RFW2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS20330
gene id: 450851:PHZ_RS20330
uniprot id: B4RIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

450851:PHZ RS01160
gene id: 450851:PHZ_RS01160
uniprot id: B4RD23
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

450851:PHZ RS17305
gene id: 450851:PHZ_RS17305
uniprot id: B4RA25
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

450851:PHZ RS17630
gene id: 450851:PHZ_RS17630
uniprot id: B4RAJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

450851:PHZ RS01355
gene id: 450851:PHZ_RS01355
uniprot id: B4RD54
names: Similarity
messages: Belongs to the peptidase S41A family.

450851:PHZ RS03705
gene id: 450851:PHZ_RS03705
uniprot id: B4RFL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

450851:PHZ RS06880
gene id: 450851:PHZ_RS06880
uniprot id: B4R8N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

450851:PHZ RS11745
gene id: 450851:PHZ_RS11745
uniprot id: B4REM3
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS16360
gene id: 450851:PHZ_RS16360
uniprot id: B4R8Z2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

450851:PHZ RS10930
gene id: 450851:PHZ_RS10930
uniprot id: B4RDL2
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

450851:PHZ RS18925
gene id: 450851:PHZ_RS18925
uniprot id: B4RC36
names: Similarity
messages: Belongs to the GST superfamily.

450851:PHZ RS17520
gene id: 450851:PHZ_RS17520
uniprot id: B4RA66
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

450851:PHZ RS04840
gene id: 450851:PHZ_RS04840
uniprot id: B4RGT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

450851:PHZ RS16015
gene id: 450851:PHZ_RS16015
uniprot id: B4R8T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

450851:PHZ RS19100
gene id: 450851:PHZ_RS19100
uniprot id: B4RC71
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS00030
gene id: 450851:PHZ_RS00030
uniprot id: B4RBG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

450851:PHZ RS13020
gene id: 450851:PHZ_RS13020
uniprot id: B4RFV0
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS19690
gene id: 450851:PHZ_RS19690
uniprot id: B4RHZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

450851:PHZ RS03140
gene id: 450851:PHZ_RS03140
uniprot id: B4RF08
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

450851:PHZ RS11085
gene id: 450851:PHZ_RS11085
uniprot id: B4RDZ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS12040
gene id: 450851:PHZ_RS12040
uniprot id: B4RES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

450851:PHZ RS03110
gene id: 450851:PHZ_RS03110
uniprot id: B4RF02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

450851:PHZ RS04200
gene id: 450851:PHZ_RS04200
uniprot id: B4RG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS05400
gene id: 450851:PHZ_RS05400
uniprot id: B4RHE1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

450851:PHZ RS09885
gene id: 450851:PHZ_RS09885
uniprot id: B4RCM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

450851:PHZ RS08600
gene id: 450851:PHZ_RS08600
uniprot id: B4RAG5
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

450851:PHZ RS06190
gene id: 450851:PHZ_RS06190
uniprot id: B4R802
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Vgb family.
messages: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
messages: Monomer.

450851:PHZ RS15935
gene id: 450851:PHZ_RS15935
uniprot id: B4R8R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

450851:PHZ RS07235
gene id: 450851:PHZ_RS07235
uniprot id: B4R957
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS20850
gene id: 450851:PHZ_RS20850
uniprot id: B4RIK7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

450851:PHZ RS02930
gene id: 450851:PHZ_RS02930
uniprot id: B4REW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

450851:PHZ RS12315
gene id: 450851:PHZ_RS12315
uniprot id: B4RF67
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

450851:PHZ RS18970
gene id: 450851:PHZ_RS18970
uniprot id: B4RC45
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS14050
gene id: 450851:PHZ_RS14050
uniprot id: B4RH01
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS01750
gene id: 450851:PHZ_RS01750
uniprot id: B4RDN3
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

450851:PHZ RS13695
gene id: 450851:PHZ_RS13695
uniprot id: B4RGH2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

450851:PHZ RS17155
gene id: 450851:PHZ_RS17155
uniprot id: B4R9Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

450851:PHZ RS06830
gene id: 450851:PHZ_RS06830
uniprot id: B4R8M1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

450851:PHZ RS00265
gene id: 450851:PHZ_RS00265
uniprot id: B4RBK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

450851:PHZ RS16855
gene id: 450851:PHZ_RS16855
uniprot id: B4R9J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

450851:PHZ RS01605
gene id: 450851:PHZ_RS01605
uniprot id: B4RDA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS01555
gene id: 450851:PHZ_RS01555
uniprot id: B4RD93
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS03065
gene id: 450851:PHZ_RS03065
uniprot id: B4REZ3
names: Similarity
messages: Belongs to the TPP enzyme family.

450851:PHZ RS01475
gene id: 450851:PHZ_RS01475
uniprot id: B4RD77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

450851:PHZ RS06875
gene id: 450851:PHZ_RS06875
uniprot id: B4R8N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

450851:PHZ RS02835
gene id: 450851:PHZ_RS02835
uniprot id: B4REV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

450851:PHZ RS10175
gene id: 450851:PHZ_RS10175
uniprot id: B4RCS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

450851:PHZ RS17515
gene id: 450851:PHZ_RS17515
uniprot id: B4RA65
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

450851:PHZ RS00990
gene id: 450851:PHZ_RS00990
uniprot id: B4RCJ8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

450851:PHZ RS01760
gene id: 450851:PHZ_RS01760
uniprot id: B4RDN5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

450851:PHZ RS06380
gene id: 450851:PHZ_RS06380
uniprot id: B4R835
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

450851:PHZ RS14260
gene id: 450851:PHZ_RS14260
uniprot id: B4RH37
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

450851:PHZ RS20760
gene id: 450851:PHZ_RS20760
uniprot id: B4RIJ0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

450851:PHZ RS02000
gene id: 450851:PHZ_RS02000
uniprot id: B4RDT0
names: Similarity
messages: Belongs to the GST superfamily.

450851:PHZ RS06910
gene id: 450851:PHZ_RS06910
uniprot id: B4R8N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

450851:PHZ RS16515
gene id: 450851:PHZ_RS16515
uniprot id: B4R9C6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

450851:PHZ RS09430
gene id: 450851:PHZ_RS09430
uniprot id: B4RBS3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

450851:PHZ RS04500
gene id: 450851:PHZ_RS04500
uniprot id: B4RGB5
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS03625
gene id: 450851:PHZ_RS03625
uniprot id: B4RFK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS19465
gene id: 450851:PHZ_RS19465
uniprot id: B4RD02
names: Similarity
messages: Belongs to the RelE toxin family.

450851:PHZ RS08905
gene id: 450851:PHZ_RS08905
uniprot id: B4RAX3
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS16420
gene id: 450851:PHZ_RS16420
uniprot id: B4R903
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

450851:PHZ RS04040
gene id: 450851:PHZ_RS04040
uniprot id: B4RG33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

450851:PHZ RS14265
gene id: 450851:PHZ_RS14265
uniprot id: B4RH38
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

450851:PHZ RS12805
gene id: 450851:PHZ_RS12805
uniprot id: B4RFF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

450851:PHZ RS08995
gene id: 450851:PHZ_RS08995
uniprot id: B4RAZ1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

450851:PHZ RS15380
gene id: 450851:PHZ_RS15380
uniprot id: B4R866
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS12515
gene id: 450851:PHZ_RS12515
uniprot id: B4RFA1
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

450851:PHZ RS09340
gene id: 450851:PHZ_RS09340
uniprot id: B4RBQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

450851:PHZ RS11190
gene id: 450851:PHZ_RS11190
uniprot id: B4RE17
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

450851:PHZ RS05060
gene id: 450851:PHZ_RS05060
uniprot id: B4RGX5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

450851:PHZ RS03590
gene id: 450851:PHZ_RS03590
uniprot id: B4RFJ7
names: Similarity
messages: Belongs to the peptidase A24 family.

450851:PHZ RS18955
gene id: 450851:PHZ_RS18955
uniprot id: B4RC42
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

450851:PHZ RS14400
gene id: 450851:PHZ_RS14400
uniprot id: B4RH64
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

450851:PHZ RS00255
gene id: 450851:PHZ_RS00255
uniprot id: B4RBK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

450851:PHZ RS05200
gene id: 450851:PHZ_RS05200
uniprot id: B4RHA7
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS03810
gene id: 450851:PHZ_RS03810
uniprot id: B4RFN5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

450851:PHZ RS18485
gene id: 450851:PHZ_RS18485
uniprot id: B4RBA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

450851:PHZ RS02270
gene id: 450851:PHZ_RS02270
uniprot id: B4RE90
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

450851:PHZ RS16690
gene id: 450851:PHZ_RS16690
uniprot id: B4R9F9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

450851:PHZ RS02725
gene id: 450851:PHZ_RS02725
uniprot id: B4REH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS07085
gene id: 450851:PHZ_RS07085
uniprot id: B4R927
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

450851:PHZ RS19585
gene id: 450851:PHZ_RS19585
uniprot id: B4RHY1
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS06700
gene id: 450851:PHZ_RS06700
uniprot id: B4R8J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

450851:PHZ RS09600
gene id: 450851:PHZ_RS09600
uniprot id: B4RBV6
names: Similarity
messages: Belongs to the Gfa family.

450851:PHZ RS00180
gene id: 450851:PHZ_RS00180
uniprot id: B4RBI7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

450851:PHZ RS07765
gene id: 450851:PHZ_RS07765
uniprot id: B4R9R3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS18320
gene id: 450851:PHZ_RS18320
uniprot id: B4RB74
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

450851:PHZ RS07135
gene id: 450851:PHZ_RS07135
uniprot id: B4R937
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

450851:PHZ RS02590
gene id: 450851:PHZ_RS02590
uniprot id: B4REF0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS14505
gene id: 450851:PHZ_RS14505
uniprot id: B4RH81
names: Similarity
messages: Belongs to the pirin family.

450851:PHZ RS05465
gene id: 450851:PHZ_RS05465
uniprot id: B4RHF4
names: Similarity
messages: Belongs to the BolA/IbaG family.

450851:PHZ RS04415
gene id: 450851:PHZ_RS04415
uniprot id: B4RGA0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS15215
gene id: 450851:PHZ_RS15215
uniprot id: B4RHW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS10740
gene id: 450851:PHZ_RS10740
uniprot id: B4RDH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

450851:PHZ RS09725
gene id: 450851:PHZ_RS09725
uniprot id: B4RBY0
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

450851:PHZ RS08845
gene id: 450851:PHZ_RS08845
uniprot id: B4RAW3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

450851:PHZ RS09285
gene id: 450851:PHZ_RS09285
uniprot id: B4RB41
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

450851:PHZ RS15090
gene id: 450851:PHZ_RS15090
uniprot id: B4RHU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

450851:PHZ RS11440
gene id: 450851:PHZ_RS11440
uniprot id: B4RE61
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

450851:PHZ RS20755
gene id: 450851:PHZ_RS20755
uniprot id: B4RII9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

450851:PHZ RS14430
gene id: 450851:PHZ_RS14430
uniprot id: B4RH69
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

450851:PHZ RS01920
gene id: 450851:PHZ_RS01920
uniprot id: B4RDR4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS14600
gene id: 450851:PHZ_RS14600
uniprot id: B4RH95
names: Subcellular Location Annotation
messages: Cytoplasm

450851:PHZ RS06305
gene id: 450851:PHZ_RS06305
uniprot id: B4R822
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

450851:PHZ RS08645
gene id: 450851:PHZ_RS08645
uniprot id: B4RAH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

450851:PHZ RS22835
gene id: 450851:PHZ_RS22835
uniprot id: B4RB77
names: Similarity
messages: Belongs to the UPF0111 family.

450851:PHZ RS05600
gene id: 450851:PHZ_RS05600
uniprot id: B4RHH8
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS04100
gene id: 450851:PHZ_RS04100
uniprot id: B4RG44
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

450851:PHZ RS07865
gene id: 450851:PHZ_RS07865
uniprot id: B4R9T0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

450851:PHZ RS01565
gene id: 450851:PHZ_RS01565
uniprot id: B4RD95
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS00995
gene id: 450851:PHZ_RS00995
uniprot id: B4RCJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

450851:PHZ RS16510
gene id: 450851:PHZ_RS16510
uniprot id: B4R9C5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

450851:PHZ RS05480
gene id: 450851:PHZ_RS05480
uniprot id: B4RHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS06850
gene id: 450851:PHZ_RS06850
uniprot id: B4R8M5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

450851:PHZ RS19550
gene id: 450851:PHZ_RS19550
uniprot id: B4RHX4
names: Similarity
messages: Belongs to the autoinducer synthase family.

450851:PHZ RS16685
gene id: 450851:PHZ_RS16685
uniprot id: B4R9F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

450851:PHZ RS19135
gene id: 450851:PHZ_RS19135
uniprot id: B4RC78
names: Similarity
messages: Belongs to the DEAD box helicase family.

450851:PHZ RS04220
gene id: 450851:PHZ_RS04220
uniprot id: B4RG67
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

450851:PHZ RS03255
gene id: 450851:PHZ_RS03255
uniprot id: B4RF29
names: Similarity
messages: Belongs to the pirin family.

450851:PHZ RS06045
gene id: 450851:PHZ_RS06045
uniprot id: B4R7Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

450851:PHZ RS06235
gene id: 450851:PHZ_RS06235
uniprot id: B4R811
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS04945
gene id: 450851:PHZ_RS04945
uniprot id: B4RGV3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

450851:PHZ RS06825
gene id: 450851:PHZ_RS06825
uniprot id: B4R8M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

450851:PHZ RS19720
gene id: 450851:PHZ_RS19720
uniprot id: B4RI01
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

450851:PHZ RS15925
gene id: 450851:PHZ_RS15925
uniprot id: B4R8R6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

450851:PHZ RS07645
gene id: 450851:PHZ_RS07645
uniprot id: B4R9P1
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

450851:PHZ RS01895
gene id: 450851:PHZ_RS01895
uniprot id: B4RDQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

450851:PHZ RS04700
gene id: 450851:PHZ_RS04700
uniprot id: B4RGQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

450851:PHZ RS09720
gene id: 450851:PHZ_RS09720
uniprot id: B4RBX9
names: Similarity
messages: Belongs to the citrate synthase family.

450851:PHZ RS05265
gene id: 450851:PHZ_RS05265
uniprot id: B4RHB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

450851:PHZ RS09205
gene id: 450851:PHZ_RS09205
uniprot id: B4RB27
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

450851:PHZ RS12390
gene id: 450851:PHZ_RS12390
uniprot id: B4RF81
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

450851:PHZ RS20950
gene id: 450851:PHZ_RS20950
uniprot id: B4RIN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

450851:PHZ RS10035
gene id: 450851:PHZ_RS10035
uniprot id: B4RCP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

450851:PHZ RS18030
gene id: 450851:PHZ_RS18030
uniprot id: B4RAR5
names: Similarity
messages: Belongs to the pyruvate kinase family.

450851:PHZ RS01075
gene id: 450851:PHZ_RS01075
uniprot id: B4RCL3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

450851:PHZ RS04995
gene id: 450851:PHZ_RS04995
uniprot id: B4RGW2
names: Subcellular Location Annotation
messages: Periplasm

450851:PHZ RS11100
gene id: 450851:PHZ_RS11100
uniprot id: B4RE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS16585
gene id: 450851:PHZ_RS16585
uniprot id: B4R9E0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

450851:PHZ RS06730
gene id: 450851:PHZ_RS06730
uniprot id: B4R8K1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

450851:PHZ RS02955
gene id: 450851:PHZ_RS02955
uniprot id: B4REX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

450851:PHZ RS15000
gene id: 450851:PHZ_RS15000
uniprot id: B4RHS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

450851:PHZ RS16040
gene id: 450851:PHZ_RS16040
uniprot id: B4R8T7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

450851:PHZ RS09880
gene id: 450851:PHZ_RS09880
uniprot id: B4RCL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

450851:PHZ RS02690
gene id: 450851:PHZ_RS02690
uniprot id: B4REG9
names: Function
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.

450851:PHZ RS05055
gene id: 450851:PHZ_RS05055
uniprot id: B4RGX4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

450851:PHZ RS01060
gene id: 450851:PHZ_RS01060
uniprot id: B4RCL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

450851:PHZ RS05170
gene id: 450851:PHZ_RS05170
uniprot id: B4RGZ6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

450851:PHZ RS04065
gene id: 450851:PHZ_RS04065
uniprot id: B4RG38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

450851:PHZ RS02440
gene id: 450851:PHZ_RS02440
uniprot id: B4REC3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

450851:PHZ RS11645
gene id: 450851:PHZ_RS11645
uniprot id: B4REK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS19065
gene id: 450851:PHZ_RS19065
uniprot id: B4RC64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

450851:PHZ RS07460
gene id: 450851:PHZ_RS07460
uniprot id: B4R999
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

450851:PHZ RS14325
gene id: 450851:PHZ_RS14325
uniprot id: B4RH49
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS00705
gene id: 450851:PHZ_RS00705
uniprot id: B4RCE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

450851:PHZ RS02705
gene id: 450851:PHZ_RS02705
uniprot id: B4REH2
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS10285
gene id: 450851:PHZ_RS10285
uniprot id: B4RCU2
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

450851:PHZ RS06040
gene id: 450851:PHZ_RS06040
uniprot id: B4R7Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

450851:PHZ RS07650
gene id: 450851:PHZ_RS07650
uniprot id: B4R9P2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

450851:PHZ RS02745
gene id: 450851:PHZ_RS02745
uniprot id: B4REI0
names: Cofactor
names: Similarity
messages: Belongs to the GARS family.
messages: Binds 2 magnesium or manganese ions per subunit.

450851:PHZ RS12500
gene id: 450851:PHZ_RS12500
uniprot id: B4RF98
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS02860
gene id: 450851:PHZ_RS02860
uniprot id: B4REV4
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS03765
gene id: 450851:PHZ_RS03765
uniprot id: B4RFM7
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

450851:PHZ RS04460
gene id: 450851:PHZ_RS04460
uniprot id: B4RGA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS15920
gene id: 450851:PHZ_RS15920
uniprot id: B4R8R5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

450851:PHZ RS12730
gene id: 450851:PHZ_RS12730
uniprot id: B4RFE0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

450851:PHZ RS10375
gene id: 450851:PHZ_RS10375
uniprot id: B4RCV9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

450851:PHZ RS08960
gene id: 450851:PHZ_RS08960
uniprot id: B4RAY4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS00190
gene id: 450851:PHZ_RS00190
uniprot id: B4RBI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

450851:PHZ RS03665
gene id: 450851:PHZ_RS03665
uniprot id: B4RFK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS19845
gene id: 450851:PHZ_RS19845
uniprot id: B4RI22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

450851:PHZ RS08500
gene id: 450851:PHZ_RS08500
uniprot id: B4RAE6
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS10595
gene id: 450851:PHZ_RS10595
uniprot id: B4RDE7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

450851:PHZ RS01820
gene id: 450851:PHZ_RS01820
uniprot id: B4RDP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

450851:PHZ RS08510
gene id: 450851:PHZ_RS08510
uniprot id: B4RAE8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

450851:PHZ RS10775
gene id: 450851:PHZ_RS10775
uniprot id: B4RDI1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

450851:PHZ RS06885
gene id: 450851:PHZ_RS06885
uniprot id: B4R8N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

450851:PHZ RS13520
gene id: 450851:PHZ_RS13520
uniprot id: B4RGD7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

450851:PHZ RS12295
gene id: 450851:PHZ_RS12295
uniprot id: B4RF63
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

450851:PHZ RS06970
gene id: 450851:PHZ_RS06970
uniprot id: B4R8P9
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

450851:PHZ RS03900
gene id: 450851:PHZ_RS03900
uniprot id: B4RFP8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS08150
gene id: 450851:PHZ_RS08150
uniprot id: B4RA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Periplasm

450851:PHZ RS09450
gene id: 450851:PHZ_RS09450
uniprot id: B4RBS7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS05555
gene id: 450851:PHZ_RS05555
uniprot id: B4RHH0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

450851:PHZ RS09490
gene id: 450851:PHZ_RS09490
uniprot id: B4RBT5
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

450851:PHZ RS06960
gene id: 450851:PHZ_RS06960
uniprot id: B4R8P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

450851:PHZ RS11105
gene id: 450851:PHZ_RS11105
uniprot id: B4RE02
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

450851:PHZ RS15760
gene id: 450851:PHZ_RS15760
uniprot id: B4R8D2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

450851:PHZ RS04260
gene id: 450851:PHZ_RS04260
uniprot id: B4RG74
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

450851:PHZ RS11090
gene id: 450851:PHZ_RS11090
uniprot id: B4RDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS12140
gene id: 450851:PHZ_RS12140
uniprot id: B4RET9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

450851:PHZ RS10920
gene id: 450851:PHZ_RS10920
uniprot id: B4RDL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

450851:PHZ RS09410
gene id: 450851:PHZ_RS09410
uniprot id: B4RBR9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

450851:PHZ RS14755
gene id: 450851:PHZ_RS14755
uniprot id: B4RHM9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

450851:PHZ RS04300
gene id: 450851:PHZ_RS04300
uniprot id: B4RG80
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

450851:PHZ RS01935
gene id: 450851:PHZ_RS01935
uniprot id: B4RDR7
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS08040
gene id: 450851:PHZ_RS08040
uniprot id: B4R9V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

450851:PHZ RS02040
gene id: 450851:PHZ_RS02040
uniprot id: B4RDT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

450851:PHZ RS00965
gene id: 450851:PHZ_RS00965
uniprot id: B4RCJ3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

450851:PHZ RS18160
gene id: 450851:PHZ_RS18160
uniprot id: B4RAT9
names: Similarity
messages: Belongs to the PhzF family.

450851:PHZ RS16840
gene id: 450851:PHZ_RS16840
uniprot id: B4R9I8
names: Subcellular Location Annotation
messages: Cytoplasm

450851:PHZ RS09550
gene id: 450851:PHZ_RS09550
uniprot id: B4RBU6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

450851:PHZ RS06810
gene id: 450851:PHZ_RS06810
uniprot id: B4R8L7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

450851:PHZ RS16455
gene id: 450851:PHZ_RS16455
uniprot id: B4R9B5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

450851:PHZ RS12870
gene id: 450851:PHZ_RS12870
uniprot id: B4RFS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

450851:PHZ RS16750
gene id: 450851:PHZ_RS16750
uniprot id: B4R9H1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS18290
gene id: 450851:PHZ_RS18290
uniprot id: B4RB68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

450851:PHZ RS15660
gene id: 450851:PHZ_RS15660
uniprot id: B4R8B5
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

450851:PHZ RS09165
gene id: 450851:PHZ_RS09165
uniprot id: B4RB19
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

450851:PHZ RS14625
gene id: 450851:PHZ_RS14625
uniprot id: B4RH98
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS18465
gene id: 450851:PHZ_RS18465
uniprot id: B4RBA1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

450851:PHZ RS18540
gene id: 450851:PHZ_RS18540
uniprot id: B4RBB5
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

450851:PHZ RS12900
gene id: 450851:PHZ_RS12900
uniprot id: B4RFS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

450851:PHZ RS23490
gene id: 450851:PHZ_RS23490
uniprot id: B4RAN2
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS15765
gene id: 450851:PHZ_RS15765
uniprot id: B4R8D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

450851:PHZ RS18600
gene id: 450851:PHZ_RS18600
uniprot id: B4RBC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS08910
gene id: 450851:PHZ_RS08910
uniprot id: B4RAX4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

450851:PHZ RS02130
gene id: 450851:PHZ_RS02130
uniprot id: B4RDV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

450851:PHZ RS02335
gene id: 450851:PHZ_RS02335
uniprot id: B4REA4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS00920
gene id: 450851:PHZ_RS00920
uniprot id: B4RCI5
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

450851:PHZ RS08385
gene id: 450851:PHZ_RS08385
uniprot id: B4RAC6
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

450851:PHZ RS05050
gene id: 450851:PHZ_RS05050
uniprot id: B4RGX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

450851:PHZ RS11805
gene id: 450851:PHZ_RS11805
uniprot id: B4REN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

450851:PHZ RS13765
gene id: 450851:PHZ_RS13765
uniprot id: B4RGI7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

450851:PHZ RS02935
gene id: 450851:PHZ_RS02935
uniprot id: B4REW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

450851:PHZ RS04585
gene id: 450851:PHZ_RS04585
uniprot id: B4RGD2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

450851:PHZ RS15460
gene id: 450851:PHZ_RS15460
uniprot id: B4R879
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS03245
gene id: 450851:PHZ_RS03245
uniprot id: B4RF27
names: Similarity
messages: Belongs to the YciI family.

450851:PHZ RS20165
gene id: 450851:PHZ_RS20165
uniprot id: B4RI78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

450851:PHZ RS20925
gene id: 450851:PHZ_RS20925
uniprot id: B4RIM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

450851:PHZ RS14070
gene id: 450851:PHZ_RS14070
uniprot id: B4RH05
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS09435
gene id: 450851:PHZ_RS09435
uniprot id: B4RBS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

450851:PHZ RS12640
gene id: 450851:PHZ_RS12640
uniprot id: B4RFC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

450851:PHZ RS17000
gene id: 450851:PHZ_RS17000
uniprot id: B4R9L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

450851:PHZ RS13170
gene id: 450851:PHZ_RS13170
uniprot id: B4RFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS01420
gene id: 450851:PHZ_RS01420
uniprot id: B4RD67
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

450851:PHZ RS15180
gene id: 450851:PHZ_RS15180
uniprot id: B4RHV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

450851:PHZ RS00410
gene id: 450851:PHZ_RS00410
uniprot id: B4RBM8
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

450851:PHZ RS17825
gene id: 450851:PHZ_RS17825
uniprot id: B4RAM8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

450851:PHZ RS08495
gene id: 450851:PHZ_RS08495
uniprot id: B4RAE5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

450851:PHZ RS09750
gene id: 450851:PHZ_RS09750
uniprot id: B4RBY5
names: Similarity
messages: Belongs to the Skp family.

450851:PHZ RS03015
gene id: 450851:PHZ_RS03015
uniprot id: B4REY4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS01875
gene id: 450851:PHZ_RS01875
uniprot id: B4RDQ6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

450851:PHZ RS18700
gene id: 450851:PHZ_RS18700
uniprot id: B4RBE3
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

450851:PHZ RS06100
gene id: 450851:PHZ_RS06100
uniprot id: B4R7Z1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

450851:PHZ RS05410
gene id: 450851:PHZ_RS05410
uniprot id: B4RHE3
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

450851:PHZ RS07275
gene id: 450851:PHZ_RS07275
uniprot id: B4R965
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

450851:PHZ RS06925
gene id: 450851:PHZ_RS06925
uniprot id: B4R8P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

450851:PHZ RS01500
gene id: 450851:PHZ_RS01500
uniprot id: B4RD81
names: Similarity
messages: Belongs to the AlaDH/PNT family.

450851:PHZ RS04510
gene id: 450851:PHZ_RS04510
uniprot id: B4RGB7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

450851:PHZ RS18480
gene id: 450851:PHZ_RS18480
uniprot id: B4RBA4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

450851:PHZ RS18775
gene id: 450851:PHZ_RS18775
uniprot id: B4RC09
names: Similarity
messages: Belongs to the YggT family.

450851:PHZ RS20845
gene id: 450851:PHZ_RS20845
uniprot id: B4RIK6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

450851:PHZ RS02465
gene id: 450851:PHZ_RS02465
uniprot id: B4REC7
names: Similarity
messages: Belongs to the universal stress protein A family.

450851:PHZ RS06480
gene id: 450851:PHZ_RS06480
uniprot id: B4R8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

450851:PHZ RS02750
gene id: 450851:PHZ_RS02750
uniprot id: B4REI1
names: Similarity
messages: Belongs to the AHA1 family.

450851:PHZ RS02920
gene id: 450851:PHZ_RS02920
uniprot id: B4REW6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS13025
gene id: 450851:PHZ_RS13025
uniprot id: B4RFV1
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

450851:PHZ RS04305
gene id: 450851:PHZ_RS04305
uniprot id: B4RG81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: In C.crescentus, the flagellar filament is composed of multiple flagellins of 29 kDa; 27 kDa and 25 kDa.
messages: Secreted

450851:PHZ RS03380
gene id: 450851:PHZ_RS03380
uniprot id: B4RF52
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

450851:PHZ RS19365
gene id: 450851:PHZ_RS19365
uniprot id: B4RCY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

450851:PHZ RS09540
gene id: 450851:PHZ_RS09540
uniprot id: B4RBU4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

450851:PHZ RS04900
gene id: 450851:PHZ_RS04900
uniprot id: B4RGU4
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS02145
gene id: 450851:PHZ_RS02145
uniprot id: B4RDV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

450851:PHZ RS06990
gene id: 450851:PHZ_RS06990
uniprot id: B4R910
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

450851:PHZ RS13220
gene id: 450851:PHZ_RS13220
uniprot id: B4RFY3
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

450851:PHZ RS09665
gene id: 450851:PHZ_RS09665
uniprot id: B4RBW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

450851:PHZ RS01325
gene id: 450851:PHZ_RS01325
uniprot id: B4RD48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

450851:PHZ RS17570
gene id: 450851:PHZ_RS17570
uniprot id: B4RA75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

450851:PHZ RS11585
gene id: 450851:PHZ_RS11585
uniprot id: B4RE87
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS07220
gene id: 450851:PHZ_RS07220
uniprot id: B4R954
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS20610
gene id: 450851:PHZ_RS20610
uniprot id: B4RIG3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

450851:PHZ RS18985
gene id: 450851:PHZ_RS18985
uniprot id: B4RC48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

450851:PHZ RS02075
gene id: 450851:PHZ_RS02075
uniprot id: B4RDU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

450851:PHZ RS07680
gene id: 450851:PHZ_RS07680
uniprot id: B4R9P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

450851:PHZ RS07245
gene id: 450851:PHZ_RS07245
uniprot id: B4R959
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

450851:PHZ RS16450
gene id: 450851:PHZ_RS16450
uniprot id: B4R9B4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

450851:PHZ RS00710
gene id: 450851:PHZ_RS00710
uniprot id: B4RCE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

450851:PHZ RS19590
gene id: 450851:PHZ_RS19590
uniprot id: B4RHY2
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

450851:PHZ RS19380
gene id: 450851:PHZ_RS19380
uniprot id: B4RCY5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

450851:PHZ RS03315
gene id: 450851:PHZ_RS03315
uniprot id: B4RF40
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Binds 1 Cu(+) ion.
messages: Homotrimer.

450851:PHZ RS11885
gene id: 450851:PHZ_RS11885
uniprot id: B4REQ0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

450851:PHZ RS01405
gene id: 450851:PHZ_RS01405
uniprot id: B4RD64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

450851:PHZ RS02695
gene id: 450851:PHZ_RS02695
uniprot id: B4REH0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

450851:PHZ RS20440
gene id: 450851:PHZ_RS20440
uniprot id: B4RID1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS18900
gene id: 450851:PHZ_RS18900
uniprot id: B4RC32
names: Similarity
messages: Belongs to the peptidase M16 family.

450851:PHZ RS08515
gene id: 450851:PHZ_RS08515
uniprot id: B4RAE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

450851:PHZ RS17215
gene id: 450851:PHZ_RS17215
uniprot id: B4RA08
names: Similarity
messages: Belongs to the AlaDH/PNT family.

450851:PHZ RS02865
gene id: 450851:PHZ_RS02865
uniprot id: B4REV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

450851:PHZ RS19515
gene id: 450851:PHZ_RS19515
uniprot id: B4RD11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

450851:PHZ RS11385
gene id: 450851:PHZ_RS11385
uniprot id: B4RE52
names: Similarity
messages: Belongs to the IlvD/Edd family.

450851:PHZ RS12815
gene id: 450851:PHZ_RS12815
uniprot id: B4RFF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

450851:PHZ RS10325
gene id: 450851:PHZ_RS10325
uniprot id: B4RCV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

450851:PHZ RS06645
gene id: 450851:PHZ_RS06645
uniprot id: B4R8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

450851:PHZ RS11300
gene id: 450851:PHZ_RS11300
uniprot id: B4RE38
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS08320
gene id: 450851:PHZ_RS08320
uniprot id: B4RAB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

450851:PHZ RS04255
gene id: 450851:PHZ_RS04255
uniprot id: B4RG73
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS13655
gene id: 450851:PHZ_RS13655
uniprot id: B4RGG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

450851:PHZ RS18350
gene id: 450851:PHZ_RS18350
uniprot id: B4RB80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

450851:PHZ RS08365
gene id: 450851:PHZ_RS08365
uniprot id: B4RAC2
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS08855
gene id: 450851:PHZ_RS08855
uniprot id: B4RAW5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

450851:PHZ RS03460
gene id: 450851:PHZ_RS03460
uniprot id: B4RFH2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

450851:PHZ RS17260
gene id: 450851:PHZ_RS17260
uniprot id: B4RA16
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

450851:PHZ RS00615
gene id: 450851:PHZ_RS00615
uniprot id: B4RCC9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

450851:PHZ RS12570
gene id: 450851:PHZ_RS12570
uniprot id: B4RFB2
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS12075
gene id: 450851:PHZ_RS12075
uniprot id: B4RET0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

450851:PHZ RS01525
gene id: 450851:PHZ_RS01525
uniprot id: B4RD87
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

450851:PHZ RS10860
gene id: 450851:PHZ_RS10860
uniprot id: B4RDJ8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

450851:PHZ RS00215
gene id: 450851:PHZ_RS00215
uniprot id: B4RBJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

450851:PHZ RS11930
gene id: 450851:PHZ_RS11930
uniprot id: B4REQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

450851:PHZ RS15915
gene id: 450851:PHZ_RS15915
uniprot id: B4R8R4
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

450851:PHZ RS11470
gene id: 450851:PHZ_RS11470
uniprot id: B4RE67
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

450851:PHZ RS02740
gene id: 450851:PHZ_RS02740
uniprot id: B4REH9
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

450851:PHZ RS01540
gene id: 450851:PHZ_RS01540
uniprot id: B4RD90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

450851:PHZ RS00160
gene id: 450851:PHZ_RS00160
uniprot id: B4RBI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

450851:PHZ RS11850
gene id: 450851:PHZ_RS11850
uniprot id: B4REP2
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS18975
gene id: 450851:PHZ_RS18975
uniprot id: B4RC46
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

450851:PHZ RS04690
gene id: 450851:PHZ_RS04690
uniprot id: B4RGQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

450851:PHZ RS16880
gene id: 450851:PHZ_RS16880
uniprot id: B4R9J5
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

450851:PHZ RS00820
gene id: 450851:PHZ_RS00820
uniprot id: B4RCG6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS00600
gene id: 450851:PHZ_RS00600
uniprot id: B4RCC6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

450851:PHZ RS18645
gene id: 450851:PHZ_RS18645
uniprot id: B4RBD3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

450851:PHZ RS08100
gene id: 450851:PHZ_RS08100
uniprot id: B4R9X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

450851:PHZ RS10880
gene id: 450851:PHZ_RS10880
uniprot id: B4RDK2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

450851:PHZ RS19510
gene id: 450851:PHZ_RS19510
uniprot id: B4RD10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

450851:PHZ RS20625
gene id: 450851:PHZ_RS20625
uniprot id: B4RIG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

450851:PHZ RS19905
gene id: 450851:PHZ_RS19905
uniprot id: B4RI34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

450851:PHZ RS06860
gene id: 450851:PHZ_RS06860
uniprot id: B4R8M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

450851:PHZ RS02470
gene id: 450851:PHZ_RS02470
uniprot id: B4REC8
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS08680
gene id: 450851:PHZ_RS08680
uniprot id: B4RAI0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

450851:PHZ RS14865
gene id: 450851:PHZ_RS14865
uniprot id: B4RHP8
names: Similarity
messages: Belongs to the peptidase M1 family.

450851:PHZ RS20875
gene id: 450851:PHZ_RS20875
uniprot id: B4RIL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

450851:PHZ RS15850
gene id: 450851:PHZ_RS15850
uniprot id: B4R8Q3
names: Subcellular Location Annotation
messages: Mitochondrion

450851:PHZ RS12610
gene id: 450851:PHZ_RS12610
uniprot id: B4RFB9
names: Subcellular Location Annotation
messages: Membrane

450851:PHZ RS08610
gene id: 450851:PHZ_RS08610
uniprot id: B4RAG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

450851:PHZ RS15325
gene id: 450851:PHZ_RS15325
uniprot id: B4R856
names: Subcellular Location Annotation
messages: Cytoplasm

450851:PHZ RS09440
gene id: 450851:PHZ_RS09440
uniprot id: B4RBS5
names: Similarity
messages: Belongs to the DEAD box helicase family.

450851:PHZ RS01835
gene id: 450851:PHZ_RS01835
uniprot id: B4RDP9
names: Function
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

450851:PHZ RS07365
gene id: 450851:PHZ_RS07365
uniprot id: B4R981
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

450851:PHZ RS17160
gene id: 450851:PHZ_RS17160
uniprot id: B4R9Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

450851:PHZ RS03420
gene id: 450851:PHZ_RS03420
uniprot id: B4RFG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

450851:PHZ RS02505
gene id: 450851:PHZ_RS02505
uniprot id: B4RED4
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

450851:PHZ RS03165
gene id: 450851:PHZ_RS03165
uniprot id: B4RF13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

450851:PHZ RS19150
gene id: 450851:PHZ_RS19150
uniprot id: B4RC80
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

450851:PHZ RS17580
gene id: 450851:PHZ_RS17580
uniprot id: B4RA77
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

450851:PHZ RS14925
gene id: 450851:PHZ_RS14925
uniprot id: B4RHR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

450851:PHZ RS03265
gene id: 450851:PHZ_RS03265
uniprot id: B4RF31
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

450851:PHZ RS09070
gene id: 450851:PHZ_RS09070
uniprot id: B4RB02
names: Similarity
messages: Belongs to the FBPase class 2 family.

450851:PHZ RS01745
gene id: 450851:PHZ_RS01745
uniprot id: B4RDN2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

450851:PHZ RS00875
gene id: 450851:PHZ_RS00875
uniprot id: B4RCH7
names: Similarity
messages: Belongs to the citrate synthase family.

450851:PHZ RS05010
gene id: 450851:PHZ_RS05010
uniprot id: B4RGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

450851:PHZ RS04010
gene id: 450851:PHZ_RS04010
uniprot id: B4RG27
names: Similarity
messages: Belongs to the BolA/IbaG family.

450851:PHZ RS08085
gene id: 450851:PHZ_RS08085
uniprot id: B4R9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

450851:PHZ RS02060
gene id: 450851:PHZ_RS02060
uniprot id: B4RDU2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

450851:PHZ RS20090
gene id: 450851:PHZ_RS20090
uniprot id: B4RI67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

450851:PHZ RS19050
gene id: 450851:PHZ_RS19050
uniprot id: B4RC61
names: Similarity
messages: Belongs to the Gfa family.

450851:PHZ RS18285
gene id: 450851:PHZ_RS18285
uniprot id: B4RB67
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

450851:PHZ RS01390
gene id: 450851:PHZ_RS01390
uniprot id: B4RD61
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

450851:PHZ RS17780
gene id: 450851:PHZ_RS17780
uniprot id: B4RAM0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

450851:PHZ RS04215
gene id: 450851:PHZ_RS04215
uniprot id: B4RG66
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

450851:PHZ RS05535
gene id: 450851:PHZ_RS05535
uniprot id: B4RHG7
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

450851:PHZ RS01335
gene id: 450851:PHZ_RS01335
uniprot id: B4RD50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

450851:PHZ RS05000
gene id: 450851:PHZ_RS05000
uniprot id: B4RGW3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

450851:PHZ RS04175
gene id: 450851:PHZ_RS04175
uniprot id: B4RG59
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.