44689:DidioMp19
gene id: 44689:DidioMp19
uniprot id: Q27559
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c (By similarity).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane (By similarity).
messages: Mitochondrion inner membrane

44689:DidioMp34
gene id: 44689:DidioMp34
uniprot id: O21038
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the small subunit, it contacts several helices of the small subunit rRNA.
messages: Mitochondrion
messages: Part of the small ribosomal subunit.

44689:DidioMp41
gene id: 44689:DidioMp41
uniprot id: Q9XK79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Mitochondrion membrane

44689:DidioMp15
gene id: 44689:DidioMp15
uniprot id: Q37314
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Mitochondrion membrane

44689:DidioMp37
gene id: 44689:DidioMp37
uniprot id: Q34312
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Complex I is composed of about 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By similarity).
messages: Mitochondrion inner membrane

44689:DidioMp04
gene id: 44689:DidioMp04
uniprot id: O21049
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

44689:DidioMp03
gene id: 44689:DidioMp03
uniprot id: O21048
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Mitochondrion inner membrane

44689:DidioMp28
gene id: 44689:DidioMp28
uniprot id: O21032
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Mitochondrion

44689:DidioMp09
gene id: 44689:DidioMp09
uniprot id: O21045
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAGLIDADG endonuclease family.
messages: Mitochondrial DNA endonuclease involved in intron homing.
messages: Mitochondrion

44689:DidioMp27
gene id: 44689:DidioMp27
uniprot id: Q23891
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

44689:DidioMp16
gene id: 44689:DidioMp16
uniprot id: Q37315
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c (By similarity).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element (By similarity).
messages: Mitochondrion membrane

44689:DidioMp33
gene id: 44689:DidioMp33
uniprot id: O21037
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Mitochondrion

44689:DidioMp30
gene id: 44689:DidioMp30
uniprot id: O21034
names: Caution
names: Miscellaneous
names: Subcellular Location Annotation
messages: Found in a 14.5 kb cluster region located downstream from rpl11 gene and upstream of orf796.
messages: Mitochondrion
messages: Some authors (PubMed:9560439, PubMed:10821186) called this protein rpl5, however rpl5 is a completely different protein and stands for 60S ribosomal protein L5.

44689:DidioMp17
gene id: 44689:DidioMp17
uniprot id: P22237
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Complex I is composed of about 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Mitochondrion inner membrane

44689:DidioMp39
gene id: 44689:DidioMp39
uniprot id: Q9XPI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS4 family.
messages: Mitochondrion

44689:DidioMp02
gene id: 44689:DidioMp02
uniprot id: O21047
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Mitochondrion membrane

44689:DidioMp22
gene id: 44689:DidioMp22
uniprot id: Q23886
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Mitochondrion

44689:DidioMp36
gene id: 44689:DidioMp36
uniprot id: Q9TGM3
names: Miscellaneous
names: Subcellular Location Annotation
messages: Found in a 14.5 kb cluster region located downstream from rpl11 gene and upstream of orf796.
messages: Mitochondrion

44689:DidioMp13
gene id: 44689:DidioMp13
uniprot id: Q37312
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Mitochondrion membrane

44689:DidioMp31
gene id: 44689:DidioMp31
uniprot id: O21035
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins (By similarity). Interacts with LIAT1 (By similarity).
messages: Mitochondrion

44689:DidioMp25
gene id: 44689:DidioMp25
uniprot id: Q23889
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Mitochondrion

44689:DidioMp05
gene id: 44689:DidioMp05
uniprot id: O21050
names: Subcellular Location Annotation
messages: Mitochondrion

44689:DidioMp20
gene id: 44689:DidioMp20
uniprot id: Q23884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Mitochondrion

44689:DidioMp29
gene id: 44689:DidioMp29
uniprot id: O21033
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.
messages: Mitochondrion

44689:DidioMp11
gene id: 44689:DidioMp11
uniprot id: Q9XPJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c (By similarity).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity).
messages: Mitochondrion
messages: Mitochondrion inner membrane

44689:DidioMp18
gene id: 44689:DidioMp18
uniprot id: Q23883
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Complex I is composed of 45 different subunits. Component of the iron-sulfur (IP) fragment of the enzyme.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Mitochondrion inner membrane

44689:DidioMp21
gene id: 44689:DidioMp21
uniprot id: Q23885
names: Miscellaneous
names: Subcellular Location Annotation
messages: Found in a 14.5 kb cluster region located downstream from rpl11 gene and upstream of orf796.
messages: Mitochondrion

44689:DidioMp40
gene id: 44689:DidioMp40
uniprot id: Q9XPI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Mitochondrion

44689:DidioMp12
gene id: 44689:DidioMp12
uniprot id: Q37311
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme b groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.
messages: Mitochondrion inner membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.
messages: The protein contains an even number of transmembrane helices, fewer than predicted by bioinformatics tools.

44689:DidioMp35
gene id: 44689:DidioMp35
uniprot id: O21039
names: Caution
names: Miscellaneous
names: Subcellular Location Annotation
messages: Found in a 14.5 kb cluster region located downstream from rpl11 gene and upstream of orf796.
messages: Mitochondrion membrane
messages: Some authors (PubMed:9560439, PubMed:10821186) suggest this protein is rps11, however rps11 is a completely different gene which encodes small ribosomal subunit protein uS11.

44689:DidioMp07
gene id: 44689:DidioMp07
uniprot id: O21043
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAGLIDADG endonuclease family.
messages: Mitochondrial DNA endonuclease involved in intron homing. Cleaves only one strand of intronless DNA sequence at the site which coincides with the I-SceII cleavage recognition site.
messages: Mitochondrion
messages: The expression of ai2a in E.coli causes growth inhibition and degradation of genomic DNA.

44689:DidioMp23
gene id: 44689:DidioMp23
uniprot id: Q23887
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: Mitochondrion
messages: One of the primary rRNA binding proteins, it binds directly to 16S-like rRNA where it nucleates assembly of the head domain of the small subunit.
messages: Part of the small ribosomal subunit.

44689:DidioMp06
gene id: 44689:DidioMp06
uniprot id: O21042
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme A groups non-covalently per subunit.
messages: Binds a copper B center.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: In the N-terminal section; belongs to the heme-copper respiratory oxidase family.
messages: Mitochondrion inner membrane

44689:DidioMp14
gene id: 44689:DidioMp14
uniprot id: Q37313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Mitochondrion inner membrane

44689:DidioMp08
gene id: 44689:DidioMp08
uniprot id: O21044
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAGLIDADG endonuclease family.
messages: Mitochondrial DNA endonuclease involved in intron homing.
messages: Mitochondrion

44689:DidioMp24
gene id: 44689:DidioMp24
uniprot id: Q23888
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Mitochondrion

44689:DidioMp10
gene id: 44689:DidioMp10
uniprot id: Q9TGM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAGLIDADG endonuclease family.
messages: Mitochondrial DNA endonuclease involved in intron homing.
messages: Mitochondrion

44689:DidioMp32
gene id: 44689:DidioMp32
uniprot id: O21036
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Mitochondrion

44689:DidioMp38
gene id: 44689:DidioMp38
uniprot id: Q34313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Mitochondrion inner membrane