443254:MARPI RS03030
gene id: 443254:MARPI_RS03030
uniprot id: H2J5R9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

443254:MARPI RS10840
gene id: 443254:MARPI_RS10840
uniprot id: H2J6D8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

443254:MARPI RS05275
gene id: 443254:MARPI_RS05275
uniprot id: H2J7Z5
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS08355
gene id: 443254:MARPI_RS08355
uniprot id: H2J5E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

443254:MARPI RS10355
gene id: 443254:MARPI_RS10355
uniprot id: H2J7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS07650
gene id: 443254:MARPI_RS07650
uniprot id: H2J4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

443254:MARPI RS07830
gene id: 443254:MARPI_RS07830
uniprot id: H2J4P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

443254:MARPI RS04260
gene id: 443254:MARPI_RS04260
uniprot id: H2J790
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

443254:MARPI RS06225
gene id: 443254:MARPI_RS06225
uniprot id: H2J2Y1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

443254:MARPI RS02800
gene id: 443254:MARPI_RS02800
uniprot id: H2J5M4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

443254:MARPI RS04995
gene id: 443254:MARPI_RS04995
uniprot id: H2J7U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS07525
gene id: 443254:MARPI_RS07525
uniprot id: H2J4B0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

443254:MARPI RS03740
gene id: 443254:MARPI_RS03740
uniprot id: H2J6K5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS06625
gene id: 443254:MARPI_RS06625
uniprot id: H2J3D5
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

443254:MARPI RS03730
gene id: 443254:MARPI_RS03730
uniprot id: H2J6K3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

443254:MARPI RS01885
gene id: 443254:MARPI_RS01885
uniprot id: H2J4H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

443254:MARPI RS01880
gene id: 443254:MARPI_RS01880
uniprot id: H2J4H2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS04845
gene id: 443254:MARPI_RS04845
uniprot id: H2J7R0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

443254:MARPI RS08215
gene id: 443254:MARPI_RS08215
uniprot id: H2J546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

443254:MARPI RS01735
gene id: 443254:MARPI_RS01735
uniprot id: H2J4E8
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

443254:MARPI RS08075
gene id: 443254:MARPI_RS08075
uniprot id: H2J515
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

443254:MARPI RS03855
gene id: 443254:MARPI_RS03855
uniprot id: H2J6U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

443254:MARPI RS05900
gene id: 443254:MARPI_RS05900
uniprot id: H2J8C4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

443254:MARPI RS08890
gene id: 443254:MARPI_RS08890
uniprot id: H2J5W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

443254:MARPI RS05120
gene id: 443254:MARPI_RS05120
uniprot id: H2J7W4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

443254:MARPI RS04480
gene id: 443254:MARPI_RS04480
uniprot id: H2J7D4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

443254:MARPI RS07960
gene id: 443254:MARPI_RS07960
uniprot id: H2J4Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

443254:MARPI RS08560
gene id: 443254:MARPI_RS08560
uniprot id: H2J5I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

443254:MARPI RS06105
gene id: 443254:MARPI_RS06105
uniprot id: H2J2V8
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS07275
gene id: 443254:MARPI_RS07275
uniprot id: H2J459
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

443254:MARPI RS04565
gene id: 443254:MARPI_RS04565
uniprot id: H2J7K5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

443254:MARPI RS08550
gene id: 443254:MARPI_RS08550
uniprot id: H2J5I2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

443254:MARPI RS10820
gene id: 443254:MARPI_RS10820
uniprot id: H2J5H9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

443254:MARPI RS08155
gene id: 443254:MARPI_RS08155
uniprot id: H2J534
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS08060
gene id: 443254:MARPI_RS08060
uniprot id: H2J512
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

443254:MARPI RS07045
gene id: 443254:MARPI_RS07045
uniprot id: H2J3T5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS08510
gene id: 443254:MARPI_RS08510
uniprot id: H2J5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

443254:MARPI RS05505
gene id: 443254:MARPI_RS05505
uniprot id: H2J840
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS06790
gene id: 443254:MARPI_RS06790
uniprot id: H2J3G5
names: Similarity
messages: Belongs to the asp23 family.

443254:MARPI RS09680
gene id: 443254:MARPI_RS09680
uniprot id: H2J6R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

443254:MARPI RS07365
gene id: 443254:MARPI_RS07365
uniprot id: H2J477
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS08910
gene id: 443254:MARPI_RS08910
uniprot id: H2J5X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

443254:MARPI RS05885
gene id: 443254:MARPI_RS05885
uniprot id: H2J8C1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

443254:MARPI RS00565
gene id: 443254:MARPI_RS00565
uniprot id: H2J350
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

443254:MARPI RS03950
gene id: 443254:MARPI_RS03950
uniprot id: H2J6W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

443254:MARPI RS03665
gene id: 443254:MARPI_RS03665
uniprot id: H2J6J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

443254:MARPI RS06345
gene id: 443254:MARPI_RS06345
uniprot id: H2J304
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS06715
gene id: 443254:MARPI_RS06715
uniprot id: H2J3F0
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

443254:MARPI RS04490
gene id: 443254:MARPI_RS04490
uniprot id: H2J7D6
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS06685
gene id: 443254:MARPI_RS06685
uniprot id: H2J3E4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

443254:MARPI RS02205
gene id: 443254:MARPI_RS02205
uniprot id: H2J4V7
names: Similarity
messages: Belongs to the UPF0047 family.

443254:MARPI RS04975
gene id: 443254:MARPI_RS04975
uniprot id: H2J7T6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

443254:MARPI RS06110
gene id: 443254:MARPI_RS06110
uniprot id: H2J2V9
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS02240
gene id: 443254:MARPI_RS02240
uniprot id: H2J4W5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

443254:MARPI RS09725
gene id: 443254:MARPI_RS09725
uniprot id: H2J6R9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS01415
gene id: 443254:MARPI_RS01415
uniprot id: H2J411
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS08440
gene id: 443254:MARPI_RS08440
uniprot id: H2J5G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

443254:MARPI RS05080
gene id: 443254:MARPI_RS05080
uniprot id: H2J7V7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS07505
gene id: 443254:MARPI_RS07505
uniprot id: H2J4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

443254:MARPI RS04145
gene id: 443254:MARPI_RS04145
uniprot id: H2J6Z4
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS10615
gene id: 443254:MARPI_RS10615
uniprot id: H2J5K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

443254:MARPI RS04630
gene id: 443254:MARPI_RS04630
uniprot id: H2J7L7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

443254:MARPI RS06475
gene id: 443254:MARPI_RS06475
uniprot id: H2J3A5
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

443254:MARPI RS10385
gene id: 443254:MARPI_RS10385
uniprot id: H2J7I6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

443254:MARPI RS08415
gene id: 443254:MARPI_RS08415
uniprot id: H2J5F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

443254:MARPI RS03830
gene id: 443254:MARPI_RS03830
uniprot id: H2J6U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

443254:MARPI RS09810
gene id: 443254:MARPI_RS09810
uniprot id: H2J6T4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

443254:MARPI RS00400
gene id: 443254:MARPI_RS00400
uniprot id: H2J2U3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

443254:MARPI RS03940
gene id: 443254:MARPI_RS03940
uniprot id: H2J6W0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

443254:MARPI RS05435
gene id: 443254:MARPI_RS05435
uniprot id: H2J826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS08865
gene id: 443254:MARPI_RS08865
uniprot id: H2J5W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

443254:MARPI RS01315
gene id: 443254:MARPI_RS01315
uniprot id: H2J3Y9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

443254:MARPI RS06405
gene id: 443254:MARPI_RS06405
uniprot id: H2J316
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

443254:MARPI RS08720
gene id: 443254:MARPI_RS08720
uniprot id: H2J5T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

443254:MARPI RS00595
gene id: 443254:MARPI_RS00595
uniprot id: H2J357
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS02425
gene id: 443254:MARPI_RS02425
uniprot id: H2J578
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS07855
gene id: 443254:MARPI_RS07855
uniprot id: H2J4P5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

443254:MARPI RS02615
gene id: 443254:MARPI_RS02615
uniprot id: H2J5B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

443254:MARPI RS10210
gene id: 443254:MARPI_RS10210
uniprot id: H2J7F2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

443254:MARPI RS07150
gene id: 443254:MARPI_RS07150
uniprot id: H2J3V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

443254:MARPI RS02320
gene id: 443254:MARPI_RS02320
uniprot id: H2J4Y1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

443254:MARPI RS07480
gene id: 443254:MARPI_RS07480
uniprot id: H2J4A1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

443254:MARPI RS05905
gene id: 443254:MARPI_RS05905
uniprot id: H2J8C5
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS10825
gene id: 443254:MARPI_RS10825
uniprot id: H2J5V7
names: Similarity
messages: Belongs to the FlgM family.

443254:MARPI RS03545
gene id: 443254:MARPI_RS03545
uniprot id: H2J6G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

443254:MARPI RS00220
gene id: 443254:MARPI_RS00220
uniprot id: H2J2Q8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

443254:MARPI RS02750
gene id: 443254:MARPI_RS02750
uniprot id: H2J5L4
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS04015
gene id: 443254:MARPI_RS04015
uniprot id: H2J6X5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

443254:MARPI RS01710
gene id: 443254:MARPI_RS01710
uniprot id: H2J4E3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

443254:MARPI RS02600
gene id: 443254:MARPI_RS02600
uniprot id: H2J5B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

443254:MARPI RS10790
gene id: 443254:MARPI_RS10790
uniprot id: H2J4A8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

443254:MARPI RS00300
gene id: 443254:MARPI_RS00300
uniprot id: H2J2S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

443254:MARPI RS03290
gene id: 443254:MARPI_RS03290
uniprot id: H2J645
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS07685
gene id: 443254:MARPI_RS07685
uniprot id: H2J4L1
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

443254:MARPI RS09475
gene id: 443254:MARPI_RS09475
uniprot id: H2J6M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS05915
gene id: 443254:MARPI_RS05915
uniprot id: H2J8C7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

443254:MARPI RS02745
gene id: 443254:MARPI_RS02745
uniprot id: H2J5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

443254:MARPI RS10715
gene id: 443254:MARPI_RS10715
uniprot id: H2J7Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

443254:MARPI RS05500
gene id: 443254:MARPI_RS05500
uniprot id: H2J839
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS01370
gene id: 443254:MARPI_RS01370
uniprot id: H2J400
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

443254:MARPI RS05035
gene id: 443254:MARPI_RS05035
uniprot id: H2J7U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS00890
gene id: 443254:MARPI_RS00890
uniprot id: H2J3I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS09875
gene id: 443254:MARPI_RS09875
uniprot id: H2J708
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

443254:MARPI RS05410
gene id: 443254:MARPI_RS05410
uniprot id: H2J821
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

443254:MARPI RS09705
gene id: 443254:MARPI_RS09705
uniprot id: H2J6R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS03055
gene id: 443254:MARPI_RS03055
uniprot id: H2J5S4
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS00135
gene id: 443254:MARPI_RS00135
uniprot id: H2J2P2
names: Similarity
messages: Belongs to the SfsA family.

443254:MARPI RS05150
gene id: 443254:MARPI_RS05150
uniprot id: H2J7X0
names: Similarity
messages: Belongs to the peptidase S16 family.

443254:MARPI RS01285
gene id: 443254:MARPI_RS01285
uniprot id: H2J3Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

443254:MARPI RS04895
gene id: 443254:MARPI_RS04895
uniprot id: H2J7S0
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

443254:MARPI RS05380
gene id: 443254:MARPI_RS05380
uniprot id: H2J815
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

443254:MARPI RS01820
gene id: 443254:MARPI_RS01820
uniprot id: H2J4G3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS06955
gene id: 443254:MARPI_RS06955
uniprot id: H2J3S1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS10860
gene id: 443254:MARPI_RS10860
uniprot id: H2J6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS01805
gene id: 443254:MARPI_RS01805
uniprot id: H2J4G0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

443254:MARPI RS10400
gene id: 443254:MARPI_RS10400
uniprot id: H2J7I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS04980
gene id: 443254:MARPI_RS04980
uniprot id: H2J7T7
names: Similarity
messages: Belongs to the peptidase M29 family.

443254:MARPI RS06815
gene id: 443254:MARPI_RS06815
uniprot id: H2J3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

443254:MARPI RS02775
gene id: 443254:MARPI_RS02775
uniprot id: H2J5L9
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

443254:MARPI RS00320
gene id: 443254:MARPI_RS00320
uniprot id: H2J2S7
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS08195
gene id: 443254:MARPI_RS08195
uniprot id: H2J542
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

443254:MARPI RS07420
gene id: 443254:MARPI_RS07420
uniprot id: H2J490
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

443254:MARPI RS00385
gene id: 443254:MARPI_RS00385
uniprot id: H2J2U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS05945
gene id: 443254:MARPI_RS05945
uniprot id: H2J8D3
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

443254:MARPI RS08845
gene id: 443254:MARPI_RS08845
uniprot id: H2J5V9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

443254:MARPI RS07205
gene id: 443254:MARPI_RS07205
uniprot id: H2J445
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

443254:MARPI RS00100
gene id: 443254:MARPI_RS00100
uniprot id: H2J2N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

443254:MARPI RS07725
gene id: 443254:MARPI_RS07725
uniprot id: H2J4L9
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

443254:MARPI RS02625
gene id: 443254:MARPI_RS02625
uniprot id: H2J5B7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

443254:MARPI RS05050
gene id: 443254:MARPI_RS05050
uniprot id: H2J7V1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

443254:MARPI RS07870
gene id: 443254:MARPI_RS07870
uniprot id: H2J4P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

443254:MARPI RS04080
gene id: 443254:MARPI_RS04080
uniprot id: H2J6Y1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

443254:MARPI RS01985
gene id: 443254:MARPI_RS01985
uniprot id: H2J4R4
names: Cofactor
names: Domain
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: An RNA-guided ssDNA endonuclease that may play a role in defense against invading mobile genetic elements. Uses short 5'-OH-ssRNA sequences as guides (gRNA) to bind complementary target DNA (tDNA) or target RNA resulting in target cleavage. The cleavage site is 10 nucleotides (nt) downstream of the target residue base-paired with the 5'-end of the gRNA. Reaction rates are fastest on 5'-OH-gRNA:tDNA followed by 5'-OH-gRNA:target RNA. gRNA between 17-21 nt supports equivalent rates of cleavage, has no preferred 5'-nt. Has weak activity on tDNA with 5'-phospho-gRNA, yielding products 1-2 nt longer (PubMed:27035975). Unlike other characterized prokaryotic Ago proteins symmetric mismatches centered around the cleavage site reduce cleavage efficiency (PubMed:28520746).
messages: Belongs to the argonaute family. Long pAgo subfamily.
messages: Cytoplasm
messages: Expressed at low levels (at protein level). Probably part of a cas1-cas2-ago operon.
messages: Has 4 domains (N-terminal, PAZ, Mid and PIWI). The N-terminal and PAZ domains are joined by linker L1, the PAZ and Mid domains are joined by linker L2. The domains assemble in 2 lobes; the PAZ lobe consists of the N-terminal, L1, PAZ and L2 domains, while the PIWI lobe has the Mid and PIWI domains. The PIWI domain assumes an RNase H fold and has the catalytic residues. Compared to orthologs, the N-terminal domain has a different secondary structure and position. The 5'-end of the gRNA is anchored between the MID and PIWI domains while the 3'-end is in the PAZ domain (PubMed:27035975). In the gRNA:tDNA complex the 5'-end of gRNA remains anchored in the Mid domain and is unpaired with tDNA, while the 3'-end of the gRNA is released from the PAZ domain. Upon release of the 3'-end of the gRNA from the PAZ domain during nucleic acid duplex formation, conformational changes allow Glu-482 to move to complete the active site. An N-lobe rearrangement allows a unique, straight orientation of the hybrid helix not seen in other Ago ternary complexes (PubMed:28520746).
messages: Unlike most prokaryotic argonautes, this is encoded in a CRISPR-cas subtype III-B locus.
messages: tDNA cleavage prefers Mn(2+) over Mg(2+) (PubMed:27035975). Cleavage probaby requires 2 divalent metal cations (By similarity).

443254:MARPI RS09930
gene id: 443254:MARPI_RS09930
uniprot id: H2J719
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

443254:MARPI RS03510
gene id: 443254:MARPI_RS03510
uniprot id: H2J6G2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

443254:MARPI RS01935
gene id: 443254:MARPI_RS01935
uniprot id: H2J4I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

443254:MARPI RS08800
gene id: 443254:MARPI_RS08800
uniprot id: H2J5V1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

443254:MARPI RS01825
gene id: 443254:MARPI_RS01825
uniprot id: H2J4G4
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

443254:MARPI RS04270
gene id: 443254:MARPI_RS04270
uniprot id: H2J792
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

443254:MARPI RS00875
gene id: 443254:MARPI_RS00875
uniprot id: H2J3I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

443254:MARPI RS06440
gene id: 443254:MARPI_RS06440
uniprot id: H2J323
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

443254:MARPI RS06355
gene id: 443254:MARPI_RS06355
uniprot id: H2J306
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

443254:MARPI RS01945
gene id: 443254:MARPI_RS01945
uniprot id: H2J4I6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

443254:MARPI RS07595
gene id: 443254:MARPI_RS07595
uniprot id: H2J4J4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS10865
gene id: 443254:MARPI_RS10865
uniprot id: H2J703
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

443254:MARPI RS03015
gene id: 443254:MARPI_RS03015
uniprot id: H2J5R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS04155
gene id: 443254:MARPI_RS04155
uniprot id: H2J6Z6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

443254:MARPI RS11075
gene id: 443254:MARPI_RS11075
uniprot id: H2J5P0
names: Subunit
messages: Homodimer.

443254:MARPI RS01450
gene id: 443254:MARPI_RS01450
uniprot id: H2J419
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

443254:MARPI RS00770
gene id: 443254:MARPI_RS00770
uniprot id: H2J391
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

443254:MARPI RS03245
gene id: 443254:MARPI_RS03245
uniprot id: H2J636
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

443254:MARPI RS01025
gene id: 443254:MARPI_RS01025
uniprot id: H2J3L5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

443254:MARPI RS05210
gene id: 443254:MARPI_RS05210
uniprot id: H2J7Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

443254:MARPI RS02475
gene id: 443254:MARPI_RS02475
uniprot id: H2J588
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

443254:MARPI RS05625
gene id: 443254:MARPI_RS05625
uniprot id: H2J863
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

443254:MARPI RS01895
gene id: 443254:MARPI_RS01895
uniprot id: H2J4H5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

443254:MARPI RS03425
gene id: 443254:MARPI_RS03425
uniprot id: H2J672
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS02010
gene id: 443254:MARPI_RS02010
uniprot id: H2J4R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

443254:MARPI RS07760
gene id: 443254:MARPI_RS07760
uniprot id: H2J4M6
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

443254:MARPI RS05070
gene id: 443254:MARPI_RS05070
uniprot id: H2J7V5
names: Similarity
messages: Belongs to the peptidase U62 family.

443254:MARPI RS00490
gene id: 443254:MARPI_RS00490
uniprot id: H2J335
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS00060
gene id: 443254:MARPI_RS00060
uniprot id: H2J2M7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

443254:MARPI RS00395
gene id: 443254:MARPI_RS00395
uniprot id: H2J2U2
names: Similarity
messages: Belongs to the UPF0102 family.

443254:MARPI RS08690
gene id: 443254:MARPI_RS08690
uniprot id: H2J5T2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

443254:MARPI RS06825
gene id: 443254:MARPI_RS06825
uniprot id: H2J3H2
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS09100
gene id: 443254:MARPI_RS09100
uniprot id: H2J681
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

443254:MARPI RS00390
gene id: 443254:MARPI_RS00390
uniprot id: H2J2U1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

443254:MARPI RS00455
gene id: 443254:MARPI_RS00455
uniprot id: H2J328
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

443254:MARPI RS03990
gene id: 443254:MARPI_RS03990
uniprot id: H2J6X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

443254:MARPI RS00375
gene id: 443254:MARPI_RS00375
uniprot id: H2J2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

443254:MARPI RS08430
gene id: 443254:MARPI_RS08430
uniprot id: H2J5F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

443254:MARPI RS05985
gene id: 443254:MARPI_RS05985
uniprot id: H2J8E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

443254:MARPI RS05215
gene id: 443254:MARPI_RS05215
uniprot id: H2J7Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

443254:MARPI RS04300
gene id: 443254:MARPI_RS04300
uniprot id: H2J798
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

443254:MARPI RS00900
gene id: 443254:MARPI_RS00900
uniprot id: H2J3J0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

443254:MARPI RS08070
gene id: 443254:MARPI_RS08070
uniprot id: H2J514
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

443254:MARPI RS04560
gene id: 443254:MARPI_RS04560
uniprot id: H2J7K4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

443254:MARPI RS00265
gene id: 443254:MARPI_RS00265
uniprot id: H2J2R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

443254:MARPI RS07405
gene id: 443254:MARPI_RS07405
uniprot id: H2J485
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS01360
gene id: 443254:MARPI_RS01360
uniprot id: H2J3Z8
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

443254:MARPI RS01960
gene id: 443254:MARPI_RS01960
uniprot id: H2J4Q9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

443254:MARPI RS04745
gene id: 443254:MARPI_RS04745
uniprot id: H2J7P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

443254:MARPI RS01410
gene id: 443254:MARPI_RS01410
uniprot id: H2J410
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS04430
gene id: 443254:MARPI_RS04430
uniprot id: H2J7C4
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS09255
gene id: 443254:MARPI_RS09255
uniprot id: H2J6B1
names: Similarity
messages: Belongs to the glutamine synthetase family.

443254:MARPI RS04510
gene id: 443254:MARPI_RS04510
uniprot id: H2J7E0
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

443254:MARPI RS01765
gene id: 443254:MARPI_RS01765
uniprot id: H2J4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

443254:MARPI RS06615
gene id: 443254:MARPI_RS06615
uniprot id: H2J3D3
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS04105
gene id: 443254:MARPI_RS04105
uniprot id: H2J6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS05925
gene id: 443254:MARPI_RS05925
uniprot id: H2J8C9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

443254:MARPI RS02640
gene id: 443254:MARPI_RS02640
uniprot id: H2J5C0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

443254:MARPI RS00095
gene id: 443254:MARPI_RS00095
uniprot id: H2J2N4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

443254:MARPI RS08705
gene id: 443254:MARPI_RS08705
uniprot id: H2J5T4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

443254:MARPI RS10070
gene id: 443254:MARPI_RS10070
uniprot id: H2J748
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

443254:MARPI RS02345
gene id: 443254:MARPI_RS02345
uniprot id: H2J563
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

443254:MARPI RS09220
gene id: 443254:MARPI_RS09220
uniprot id: H2J6A5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

443254:MARPI RS10185
gene id: 443254:MARPI_RS10185
uniprot id: H2J770
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS06090
gene id: 443254:MARPI_RS06090
uniprot id: H2J2V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

443254:MARPI RS06605
gene id: 443254:MARPI_RS06605
uniprot id: H2J3D1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

443254:MARPI RS11070
gene id: 443254:MARPI_RS11070
uniprot id: H2J5N9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

443254:MARPI RS04190
gene id: 443254:MARPI_RS04190
uniprot id: H2J776
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

443254:MARPI RS02630
gene id: 443254:MARPI_RS02630
uniprot id: H2J5B8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

443254:MARPI RS03045
gene id: 443254:MARPI_RS03045
uniprot id: H2J5S2
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS09835
gene id: 443254:MARPI_RS09835
uniprot id: H2J700
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

443254:MARPI RS06725
gene id: 443254:MARPI_RS06725
uniprot id: H2J3F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

443254:MARPI RS07320
gene id: 443254:MARPI_RS07320
uniprot id: H2J468
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS10190
gene id: 443254:MARPI_RS10190
uniprot id: H2J771
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS09315
gene id: 443254:MARPI_RS09315
uniprot id: H2J6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

443254:MARPI RS02065
gene id: 443254:MARPI_RS02065
uniprot id: H2J4T0
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS01305
gene id: 443254:MARPI_RS01305
uniprot id: H2J3Y7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

443254:MARPI RS01915
gene id: 443254:MARPI_RS01915
uniprot id: H2J4H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

443254:MARPI RS05365
gene id: 443254:MARPI_RS05365
uniprot id: H2J812
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

443254:MARPI RS00075
gene id: 443254:MARPI_RS00075
uniprot id: H2J2N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

443254:MARPI RS09280
gene id: 443254:MARPI_RS09280
uniprot id: H2J6B6
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS04650
gene id: 443254:MARPI_RS04650
uniprot id: H2J7M1
names: Similarity
messages: Belongs to the YggT family.

443254:MARPI RS05385
gene id: 443254:MARPI_RS05385
uniprot id: H2J816
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

443254:MARPI RS05545
gene id: 443254:MARPI_RS05545
uniprot id: H2J848
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

443254:MARPI RS06460
gene id: 443254:MARPI_RS06460
uniprot id: H2J3A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

443254:MARPI RS04810
gene id: 443254:MARPI_RS04810
uniprot id: H2J7Q3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

443254:MARPI RS06335
gene id: 443254:MARPI_RS06335
uniprot id: H2J302
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS08370
gene id: 443254:MARPI_RS08370
uniprot id: H2J5E9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

443254:MARPI RS03745
gene id: 443254:MARPI_RS03745
uniprot id: H2J6K6
names: Similarity
messages: Belongs to the asparaginase 1 family.

443254:MARPI RS05200
gene id: 443254:MARPI_RS05200
uniprot id: H2J7Y0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

443254:MARPI RS05310
gene id: 443254:MARPI_RS05310
uniprot id: H2J802
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

443254:MARPI RS05920
gene id: 443254:MARPI_RS05920
uniprot id: H2J8C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

443254:MARPI RS08840
gene id: 443254:MARPI_RS08840
uniprot id: H2J5V8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

443254:MARPI RS05815
gene id: 443254:MARPI_RS05815
uniprot id: H2J8A9
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

443254:MARPI RS00560
gene id: 443254:MARPI_RS00560
uniprot id: H2J349
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

443254:MARPI RS02550
gene id: 443254:MARPI_RS02550
uniprot id: H2J5A3
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS06915
gene id: 443254:MARPI_RS06915
uniprot id: H2J3R3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

443254:MARPI RS09045
gene id: 443254:MARPI_RS09045
uniprot id: H2J5Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

443254:MARPI RS02495
gene id: 443254:MARPI_RS02495
uniprot id: H2J592
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

443254:MARPI RS09070
gene id: 443254:MARPI_RS09070
uniprot id: H2J604
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

443254:MARPI RS05550
gene id: 443254:MARPI_RS05550
uniprot id: H2J849
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

443254:MARPI RS01020
gene id: 443254:MARPI_RS01020
uniprot id: H2J3L4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

443254:MARPI RS00690
gene id: 443254:MARPI_RS00690
uniprot id: H2J375
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

443254:MARPI RS03205
gene id: 443254:MARPI_RS03205
uniprot id: H2J628
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS04835
gene id: 443254:MARPI_RS04835
uniprot id: H2J7Q8
names: Similarity
messages: Belongs to the RecJ family.

443254:MARPI RS01245
gene id: 443254:MARPI_RS01245
uniprot id: H2J3X5
names: Similarity
messages: Belongs to the Skp family.

443254:MARPI RS05620
gene id: 443254:MARPI_RS05620
uniprot id: H2J862
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

443254:MARPI RS01275
gene id: 443254:MARPI_RS01275
uniprot id: H2J3Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS01420
gene id: 443254:MARPI_RS01420
uniprot id: H2J412
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

443254:MARPI RS07775
gene id: 443254:MARPI_RS07775
uniprot id: H2J4M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

443254:MARPI RS10135
gene id: 443254:MARPI_RS10135
uniprot id: H2J760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS00150
gene id: 443254:MARPI_RS00150
uniprot id: H2J2P5
names: Similarity
messages: Belongs to the threonine aldolase family.

443254:MARPI RS09335
gene id: 443254:MARPI_RS09335
uniprot id: H2J6C7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

443254:MARPI RS10580
gene id: 443254:MARPI_RS10580
uniprot id: H2J3N6
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS10390
gene id: 443254:MARPI_RS10390
uniprot id: H2J7I7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

443254:MARPI RS07250
gene id: 443254:MARPI_RS07250
uniprot id: H2J454
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

443254:MARPI RS03190
gene id: 443254:MARPI_RS03190
uniprot id: H2J625
names: Similarity
messages: Belongs to the UPF0111 family.

443254:MARPI RS04230
gene id: 443254:MARPI_RS04230
uniprot id: H2J784
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

443254:MARPI RS06165
gene id: 443254:MARPI_RS06165
uniprot id: H2J2X0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

443254:MARPI RS02610
gene id: 443254:MARPI_RS02610
uniprot id: H2J5B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS09885
gene id: 443254:MARPI_RS09885
uniprot id: H2J710
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

443254:MARPI RS01830
gene id: 443254:MARPI_RS01830
uniprot id: H2J4G5
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

443254:MARPI RS04210
gene id: 443254:MARPI_RS04210
uniprot id: H2J780
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

443254:MARPI RS06315
gene id: 443254:MARPI_RS06315
uniprot id: H2J2Z9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

443254:MARPI RS08620
gene id: 443254:MARPI_RS08620
uniprot id: H2J5J6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

443254:MARPI RS00710
gene id: 443254:MARPI_RS00710
uniprot id: H2J379
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

443254:MARPI RS06495
gene id: 443254:MARPI_RS06495
uniprot id: H2J3A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

443254:MARPI RS05990
gene id: 443254:MARPI_RS05990
uniprot id: H2J8E2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

443254:MARPI RS04450
gene id: 443254:MARPI_RS04450
uniprot id: H2J7C8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

443254:MARPI RS03585
gene id: 443254:MARPI_RS03585
uniprot id: H2J6H7
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

443254:MARPI RS05135
gene id: 443254:MARPI_RS05135
uniprot id: H2J7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS09410
gene id: 443254:MARPI_RS09410
uniprot id: H2J6E1
names: Similarity
messages: Belongs to the MotB family.

443254:MARPI RS06635
gene id: 443254:MARPI_RS06635
uniprot id: H2J3D7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

443254:MARPI RS07790
gene id: 443254:MARPI_RS07790
uniprot id: H2J4N2
names: Similarity
messages: Belongs to the ribF family.

443254:MARPI RS05930
gene id: 443254:MARPI_RS05930
uniprot id: H2J8D0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS05260
gene id: 443254:MARPI_RS05260
uniprot id: H2J7Z2
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

443254:MARPI RS05195
gene id: 443254:MARPI_RS05195
uniprot id: H2J7X9
names: Similarity
messages: Belongs to the IMPACT family.

443254:MARPI RS08210
gene id: 443254:MARPI_RS08210
uniprot id: H2J545
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

443254:MARPI RS04325
gene id: 443254:MARPI_RS04325
uniprot id: H2J7A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

443254:MARPI RS01775
gene id: 443254:MARPI_RS01775
uniprot id: H2J4F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

443254:MARPI RS09745
gene id: 443254:MARPI_RS09745
uniprot id: H2J6S3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

443254:MARPI RS05660
gene id: 443254:MARPI_RS05660
uniprot id: H2J869
names: Similarity
messages: Belongs to the RutC family.

443254:MARPI RS03340
gene id: 443254:MARPI_RS03340
uniprot id: H2J655
names: Similarity
messages: Belongs to the carbamate kinase family.

443254:MARPI RS00865
gene id: 443254:MARPI_RS00865
uniprot id: H2J3I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

443254:MARPI RS09595
gene id: 443254:MARPI_RS09595
uniprot id: H2J6P3
names: Similarity
messages: Belongs to the histone deacetylase family.

443254:MARPI RS02430
gene id: 443254:MARPI_RS02430
uniprot id: H2J579
names: Similarity
messages: Belongs to the UPF0173 family.

443254:MARPI RS09635
gene id: 443254:MARPI_RS09635
uniprot id: H2J6Q1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

443254:MARPI RS04940
gene id: 443254:MARPI_RS04940
uniprot id: H2J7S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

443254:MARPI RS08180
gene id: 443254:MARPI_RS08180
uniprot id: H2J539
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

443254:MARPI RS01865
gene id: 443254:MARPI_RS01865
uniprot id: H2J4G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

443254:MARPI RS05775
gene id: 443254:MARPI_RS05775
uniprot id: H2J8A0
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS09720
gene id: 443254:MARPI_RS09720
uniprot id: H2J6R8
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

443254:MARPI RS04135
gene id: 443254:MARPI_RS04135
uniprot id: H2J6E1
names: Similarity
messages: Belongs to the MotB family.

443254:MARPI RS02975
gene id: 443254:MARPI_RS02975
uniprot id: H2J5Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

443254:MARPI RS08085
gene id: 443254:MARPI_RS08085
uniprot id: H2J517
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

443254:MARPI RS07340
gene id: 443254:MARPI_RS07340
uniprot id: H2J472
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS03590
gene id: 443254:MARPI_RS03590
uniprot id: H2J6H8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

443254:MARPI RS05910
gene id: 443254:MARPI_RS05910
uniprot id: H2J8C6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

443254:MARPI RS05820
gene id: 443254:MARPI_RS05820
uniprot id: H2J8B0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS07990
gene id: 443254:MARPI_RS07990
uniprot id: H2J4Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

443254:MARPI RS00365
gene id: 443254:MARPI_RS00365
uniprot id: H2J2T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

443254:MARPI RS08740
gene id: 443254:MARPI_RS08740
uniprot id: H2J5U1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

443254:MARPI RS09120
gene id: 443254:MARPI_RS09120
uniprot id: H2J685
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

443254:MARPI RS05965
gene id: 443254:MARPI_RS05965
uniprot id: H2J8D7
names: Similarity
messages: Belongs to the FBPase class 2 family.

443254:MARPI RS03655
gene id: 443254:MARPI_RS03655
uniprot id: H2J6I8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS02125
gene id: 443254:MARPI_RS02125
uniprot id: H2J4U2
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS00470
gene id: 443254:MARPI_RS00470
uniprot id: H2J331
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

443254:MARPI RS05605
gene id: 443254:MARPI_RS05605
uniprot id: H2J859
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS08570
gene id: 443254:MARPI_RS08570
uniprot id: H2J5I6
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.

443254:MARPI RS03735
gene id: 443254:MARPI_RS03735
uniprot id: H2J6K4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

443254:MARPI RS04600
gene id: 443254:MARPI_RS04600
uniprot id: H2J7L3
names: Similarity
messages: Belongs to the UPF0166 family.

443254:MARPI RS03285
gene id: 443254:MARPI_RS03285
uniprot id: H2J644
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

443254:MARPI RS00760
gene id: 443254:MARPI_RS00760
uniprot id: H2J389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

443254:MARPI RS10780
gene id: 443254:MARPI_RS10780
uniprot id: H2J3V5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

443254:MARPI RS06740
gene id: 443254:MARPI_RS06740
uniprot id: H2J3F5
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS03080
gene id: 443254:MARPI_RS03080
uniprot id: H2J5S9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS02290
gene id: 443254:MARPI_RS02290
uniprot id: H2J4X5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

443254:MARPI RS03995
gene id: 443254:MARPI_RS03995
uniprot id: H2J6X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

443254:MARPI RS08080
gene id: 443254:MARPI_RS08080
uniprot id: H2J516
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

443254:MARPI RS06000
gene id: 443254:MARPI_RS06000
uniprot id: H2J8E4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

443254:MARPI RS06785
gene id: 443254:MARPI_RS06785
uniprot id: H2J3G4
names: Similarity
messages: Belongs to the MEMO1 family.

443254:MARPI RS07050
gene id: 443254:MARPI_RS07050
uniprot id: H2J3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

443254:MARPI RS08610
gene id: 443254:MARPI_RS08610
uniprot id: H2J5J4
names: Similarity
messages: Belongs to the histone deacetylase family.

443254:MARPI RS07655
gene id: 443254:MARPI_RS07655
uniprot id: H2J4K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

443254:MARPI RS10110
gene id: 443254:MARPI_RS10110
uniprot id: H2J755
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

443254:MARPI RS03515
gene id: 443254:MARPI_RS03515
uniprot id: H2J6G3
names: Similarity
messages: Belongs to the CinA family.

443254:MARPI RS04570
gene id: 443254:MARPI_RS04570
uniprot id: H2J7K6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

443254:MARPI RS10195
gene id: 443254:MARPI_RS10195
uniprot id: H2J772
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

443254:MARPI RS07385
gene id: 443254:MARPI_RS07385
uniprot id: H2J481
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

443254:MARPI RS08730
gene id: 443254:MARPI_RS08730
uniprot id: H2J5T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

443254:MARPI RS05940
gene id: 443254:MARPI_RS05940
uniprot id: H2J8D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

443254:MARPI RS02175
gene id: 443254:MARPI_RS02175
uniprot id: H2J4V1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS10255
gene id: 443254:MARPI_RS10255
uniprot id: H2J7G1
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS02165
gene id: 443254:MARPI_RS02165
uniprot id: H2J4U9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

443254:MARPI RS05440
gene id: 443254:MARPI_RS05440
uniprot id: H2J827
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS06850
gene id: 443254:MARPI_RS06850
uniprot id: H2J3Q1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

443254:MARPI RS00610
gene id: 443254:MARPI_RS00610
uniprot id: H2J360
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS09095
gene id: 443254:MARPI_RS09095
uniprot id: H2J680
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

443254:MARPI RS04900
gene id: 443254:MARPI_RS04900
uniprot id: H2J7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

443254:MARPI RS05305
gene id: 443254:MARPI_RS05305
uniprot id: H2J801
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

443254:MARPI RS00460
gene id: 443254:MARPI_RS00460
uniprot id: H2J329
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

443254:MARPI RS03460
gene id: 443254:MARPI_RS03460
uniprot id: H2J6F5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

443254:MARPI RS01140
gene id: 443254:MARPI_RS01140
uniprot id: H2J3N8
names: Similarity
messages: Belongs to the UPF0597 family.

443254:MARPI RS06935
gene id: 443254:MARPI_RS06935
uniprot id: H2J3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

443254:MARPI RS02260
gene id: 443254:MARPI_RS02260
uniprot id: H2J4W9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

443254:MARPI RS09320
gene id: 443254:MARPI_RS09320
uniprot id: H2J6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

443254:MARPI RS06415
gene id: 443254:MARPI_RS06415
uniprot id: H2J318
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

443254:MARPI RS04815
gene id: 443254:MARPI_RS04815
uniprot id: H2J7Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

443254:MARPI RS07920
gene id: 443254:MARPI_RS07920
uniprot id: H2J4Y3
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

443254:MARPI RS00930
gene id: 443254:MARPI_RS00930
uniprot id: H2J3J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

443254:MARPI RS00445
gene id: 443254:MARPI_RS00445
uniprot id: H2J326
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS03225
gene id: 443254:MARPI_RS03225
uniprot id: H2J632
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS08515
gene id: 443254:MARPI_RS08515
uniprot id: H2J5H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

443254:MARPI RS10350
gene id: 443254:MARPI_RS10350
uniprot id: H2J7H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS03120
gene id: 443254:MARPI_RS03120
uniprot id: H2J612
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

443254:MARPI RS04330
gene id: 443254:MARPI_RS04330
uniprot id: H2J7A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

443254:MARPI RS05235
gene id: 443254:MARPI_RS05235
uniprot id: H2J7Y7
names: Similarity
messages: Belongs to the ComB family.

443254:MARPI RS08050
gene id: 443254:MARPI_RS08050
uniprot id: H2J510
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

443254:MARPI RS09510
gene id: 443254:MARPI_RS09510
uniprot id: H2J6M8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

443254:MARPI RS05595
gene id: 443254:MARPI_RS05595
uniprot id: H2J857
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

443254:MARPI RS06690
gene id: 443254:MARPI_RS06690
uniprot id: H2J3E5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS00910
gene id: 443254:MARPI_RS00910
uniprot id: H2J3J2
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS11115
gene id: 443254:MARPI_RS11115
uniprot id: H2J7T5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

443254:MARPI RS02870
gene id: 443254:MARPI_RS02870
uniprot id: H2J5N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

443254:MARPI RS09060
gene id: 443254:MARPI_RS09060
uniprot id: H2J602
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

443254:MARPI RS09285
gene id: 443254:MARPI_RS09285
uniprot id: H2J6B7
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS07745
gene id: 443254:MARPI_RS07745
uniprot id: H2J4M3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

443254:MARPI RS07330
gene id: 443254:MARPI_RS07330
uniprot id: H2J470
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

443254:MARPI RS05695
gene id: 443254:MARPI_RS05695
uniprot id: H2J884
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

443254:MARPI RS06705
gene id: 443254:MARPI_RS06705
uniprot id: H2J3E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

443254:MARPI RS02995
gene id: 443254:MARPI_RS02995
uniprot id: H2J5R2
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

443254:MARPI RS04195
gene id: 443254:MARPI_RS04195
uniprot id: H2J777
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

443254:MARPI RS09015
gene id: 443254:MARPI_RS09015
uniprot id: H2J5Z3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

443254:MARPI RS02095
gene id: 443254:MARPI_RS02095
uniprot id: H2J4T6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

443254:MARPI RS08625
gene id: 443254:MARPI_RS08625
uniprot id: H2J5J7
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

443254:MARPI RS09370
gene id: 443254:MARPI_RS09370
uniprot id: H2J6D4
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS09970
gene id: 443254:MARPI_RS09970
uniprot id: H2J727
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

443254:MARPI RS07835
gene id: 443254:MARPI_RS07835
uniprot id: H2J4P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

443254:MARPI RS00915
gene id: 443254:MARPI_RS00915
uniprot id: H2J3J3
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS05295
gene id: 443254:MARPI_RS05295
uniprot id: H2J7Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

443254:MARPI RS01005
gene id: 443254:MARPI_RS01005
uniprot id: H2J3L1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

443254:MARPI RS09385
gene id: 443254:MARPI_RS09385
uniprot id: H2J6D7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

443254:MARPI RS04400
gene id: 443254:MARPI_RS04400
uniprot id: H2J7B8
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS03450
gene id: 443254:MARPI_RS03450
uniprot id: H2J6F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

443254:MARPI RS02230
gene id: 443254:MARPI_RS02230
uniprot id: H2J4W3
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

443254:MARPI RS04345
gene id: 443254:MARPI_RS04345
uniprot id: H2J7A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

443254:MARPI RS07395
gene id: 443254:MARPI_RS07395
uniprot id: H2J483
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

443254:MARPI RS04310
gene id: 443254:MARPI_RS04310
uniprot id: H2J7A0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

443254:MARPI RS06220
gene id: 443254:MARPI_RS06220
uniprot id: H2J2Y0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

443254:MARPI RS05010
gene id: 443254:MARPI_RS05010
uniprot id: H2J7U3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

443254:MARPI RS01700
gene id: 443254:MARPI_RS01700
uniprot id: H2J4E1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

443254:MARPI RS03540
gene id: 443254:MARPI_RS03540
uniprot id: H2J6G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

443254:MARPI RS10010
gene id: 443254:MARPI_RS10010
uniprot id: H2J735
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

443254:MARPI RS03825
gene id: 443254:MARPI_RS03825
uniprot id: H2J6U1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

443254:MARPI RS06180
gene id: 443254:MARPI_RS06180
uniprot id: H2J2X3
names: Similarity
messages: Belongs to the CapA family.

443254:MARPI RS10725
gene id: 443254:MARPI_RS10725
uniprot id: H2J7V8
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

443254:MARPI RS02905
gene id: 443254:MARPI_RS02905
uniprot id: H2J5P6
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS04750
gene id: 443254:MARPI_RS04750
uniprot id: H2J7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

443254:MARPI RS08275
gene id: 443254:MARPI_RS08275
uniprot id: H2J558
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

443254:MARPI RS04220
gene id: 443254:MARPI_RS04220
uniprot id: H2J782
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

443254:MARPI RS06195
gene id: 443254:MARPI_RS06195
uniprot id: H2J2X6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

443254:MARPI RS00245
gene id: 443254:MARPI_RS00245
uniprot id: H2J2R3
names: Similarity
messages: Belongs to the fabD family.

443254:MARPI RS02325
gene id: 443254:MARPI_RS02325
uniprot id: H2J4Y2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

443254:MARPI RS00720
gene id: 443254:MARPI_RS00720
uniprot id: H2J381
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

443254:MARPI RS04355
gene id: 443254:MARPI_RS04355
uniprot id: H2J7A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

443254:MARPI RS07620
gene id: 443254:MARPI_RS07620
uniprot id: H2J4J8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

443254:MARPI RS05075
gene id: 443254:MARPI_RS05075
uniprot id: H2J7V6
names: Similarity
messages: Belongs to the peptidase U62 family.

443254:MARPI RS00430
gene id: 443254:MARPI_RS00430
uniprot id: H2J2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

443254:MARPI RS04820
gene id: 443254:MARPI_RS04820
uniprot id: H2J7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

443254:MARPI RS00410
gene id: 443254:MARPI_RS00410
uniprot id: H2J2U5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS03320
gene id: 443254:MARPI_RS03320
uniprot id: H2J651
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

443254:MARPI RS06240
gene id: 443254:MARPI_RS06240
uniprot id: H2J2Y4
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS08905
gene id: 443254:MARPI_RS08905
uniprot id: H2J5X1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

443254:MARPI RS01215
gene id: 443254:MARPI_RS01215
uniprot id: H2J3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

443254:MARPI RS02300
gene id: 443254:MARPI_RS02300
uniprot id: H2J4X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

443254:MARPI RS09210
gene id: 443254:MARPI_RS09210
uniprot id: H2J6A3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

443254:MARPI RS09590
gene id: 443254:MARPI_RS09590
uniprot id: H2J6P2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

443254:MARPI RS00305
gene id: 443254:MARPI_RS00305
uniprot id: H2J2S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

443254:MARPI RS00815
gene id: 443254:MARPI_RS00815
uniprot id: H2J3A0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

443254:MARPI RS08320
gene id: 443254:MARPI_RS08320
uniprot id: H2J5D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

443254:MARPI RS07080
gene id: 443254:MARPI_RS07080
uniprot id: H2J3U2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS08420
gene id: 443254:MARPI_RS08420
uniprot id: H2J5F6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

443254:MARPI RS05995
gene id: 443254:MARPI_RS05995
uniprot id: H2J8E3
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS08825
gene id: 443254:MARPI_RS08825
uniprot id: H2J5V5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

443254:MARPI RS09405
gene id: 443254:MARPI_RS09405
uniprot id: H2J6E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

443254:MARPI RS07640
gene id: 443254:MARPI_RS07640
uniprot id: H2J4K2
names: Similarity
messages: Belongs to the YicC/YloC family.

443254:MARPI RS08605
gene id: 443254:MARPI_RS08605
uniprot id: H2J5J3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS09135
gene id: 443254:MARPI_RS09135
uniprot id: H2J688
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

443254:MARPI RS08170
gene id: 443254:MARPI_RS08170
uniprot id: H2J537
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

443254:MARPI RS01975
gene id: 443254:MARPI_RS01975
uniprot id: H2J4R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

443254:MARPI RS04130
gene id: 443254:MARPI_RS04130
uniprot id: H2J6Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

443254:MARPI RS03550
gene id: 443254:MARPI_RS03550
uniprot id: H2J6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

443254:MARPI RS00040
gene id: 443254:MARPI_RS00040
uniprot id: H2J879
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

443254:MARPI RS03240
gene id: 443254:MARPI_RS03240
uniprot id: H2J635
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS02315
gene id: 443254:MARPI_RS02315
uniprot id: H2J4Y0
names: Similarity
messages: Belongs to the FGGY kinase family.

443254:MARPI RS01720
gene id: 443254:MARPI_RS01720
uniprot id: H2J4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

443254:MARPI RS08600
gene id: 443254:MARPI_RS08600
uniprot id: H2J5J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

443254:MARPI RS02765
gene id: 443254:MARPI_RS02765
uniprot id: H2J5L7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

443254:MARPI RS07190
gene id: 443254:MARPI_RS07190
uniprot id: H2J3W4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

443254:MARPI RS00655
gene id: 443254:MARPI_RS00655
uniprot id: H2J369
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

443254:MARPI RS08190
gene id: 443254:MARPI_RS08190
uniprot id: H2J541
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

443254:MARPI RS04290
gene id: 443254:MARPI_RS04290
uniprot id: H2J796
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

443254:MARPI RS03880
gene id: 443254:MARPI_RS03880
uniprot id: H2J6V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS04185
gene id: 443254:MARPI_RS04185
uniprot id: H2J775
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

443254:MARPI RS04095
gene id: 443254:MARPI_RS04095
uniprot id: H2J6Y4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

443254:MARPI RS02170
gene id: 443254:MARPI_RS02170
uniprot id: H2J4V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

443254:MARPI RS04990
gene id: 443254:MARPI_RS04990
uniprot id: H2J7T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS03925
gene id: 443254:MARPI_RS03925
uniprot id: H2J6V7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS06295
gene id: 443254:MARPI_RS06295
uniprot id: H2J2Z5
names: Similarity
messages: Belongs to the UPF0145 family.

443254:MARPI RS01500
gene id: 443254:MARPI_RS01500
uniprot id: H2J429
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS09860
gene id: 443254:MARPI_RS09860
uniprot id: H2J705
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS06595
gene id: 443254:MARPI_RS06595
uniprot id: H2J3C9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

443254:MARPI RS00125
gene id: 443254:MARPI_RS00125
uniprot id: H2J2P0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

443254:MARPI RS07995
gene id: 443254:MARPI_RS07995
uniprot id: H2J4Z9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

443254:MARPI RS00980
gene id: 443254:MARPI_RS00980
uniprot id: H2J3K6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

443254:MARPI RS07815
gene id: 443254:MARPI_RS07815
uniprot id: H2J4N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

443254:MARPI RS03470
gene id: 443254:MARPI_RS03470
uniprot id: H2J6F7
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS04275
gene id: 443254:MARPI_RS04275
uniprot id: H2J793
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

443254:MARPI RS07955
gene id: 443254:MARPI_RS07955
uniprot id: H2J4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS04370
gene id: 443254:MARPI_RS04370
uniprot id: H2J7B2
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

443254:MARPI RS05495
gene id: 443254:MARPI_RS05495
uniprot id: H2J838
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

443254:MARPI RS04205
gene id: 443254:MARPI_RS04205
uniprot id: H2J779
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

443254:MARPI RS06370
gene id: 443254:MARPI_RS06370
uniprot id: H2J309
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

443254:MARPI RS09575
gene id: 443254:MARPI_RS09575
uniprot id: H2J6N9
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

443254:MARPI RS09735
gene id: 443254:MARPI_RS09735
uniprot id: H2J6S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

443254:MARPI RS08715
gene id: 443254:MARPI_RS08715
uniprot id: H2J5T6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

443254:MARPI RS02760
gene id: 443254:MARPI_RS02760
uniprot id: H2J5L6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

443254:MARPI RS04605
gene id: 443254:MARPI_RS04605
uniprot id: H2J7L4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

443254:MARPI RS06710
gene id: 443254:MARPI_RS06710
uniprot id: H2J3E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

443254:MARPI RS09965
gene id: 443254:MARPI_RS09965
uniprot id: H2J726
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

443254:MARPI RS02755
gene id: 443254:MARPI_RS02755
uniprot id: H2J5L5
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

443254:MARPI RS06950
gene id: 443254:MARPI_RS06950
uniprot id: H2J3S0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

443254:MARPI RS02850
gene id: 443254:MARPI_RS02850
uniprot id: H2J5N4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

443254:MARPI RS03180
gene id: 443254:MARPI_RS03180
uniprot id: H2J623
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

443254:MARPI RS04465
gene id: 443254:MARPI_RS04465
uniprot id: H2J7D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

443254:MARPI RS03670
gene id: 443254:MARPI_RS03670
uniprot id: H2J6J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

443254:MARPI RS00945
gene id: 443254:MARPI_RS00945
uniprot id: H2J3J9
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS07825
gene id: 443254:MARPI_RS07825
uniprot id: H2J4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

443254:MARPI RS08090
gene id: 443254:MARPI_RS08090
uniprot id: H2J518
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

443254:MARPI RS07980
gene id: 443254:MARPI_RS07980
uniprot id: H2J4Z6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

443254:MARPI RS06365
gene id: 443254:MARPI_RS06365
uniprot id: H2J308
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

443254:MARPI RS07610
gene id: 443254:MARPI_RS07610
uniprot id: H2J4J6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

443254:MARPI RS03305
gene id: 443254:MARPI_RS03305
uniprot id: H2J648
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

443254:MARPI RS10680
gene id: 443254:MARPI_RS10680
uniprot id: H2J6V0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

443254:MARPI RS07915
gene id: 443254:MARPI_RS07915
uniprot id: H2J4Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

443254:MARPI RS03325
gene id: 443254:MARPI_RS03325
uniprot id: H2J652
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

443254:MARPI RS02090
gene id: 443254:MARPI_RS02090
uniprot id: H2J4T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS04905
gene id: 443254:MARPI_RS04905
uniprot id: H2J7S2
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

443254:MARPI RS01385
gene id: 443254:MARPI_RS01385
uniprot id: H2J403
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

443254:MARPI RS02780
gene id: 443254:MARPI_RS02780
uniprot id: H2J5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

443254:MARPI RS00960
gene id: 443254:MARPI_RS00960
uniprot id: H2J3K2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

443254:MARPI RS02700
gene id: 443254:MARPI_RS02700
uniprot id: H2J5D2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

443254:MARPI RS01190
gene id: 443254:MARPI_RS01190
uniprot id: H2J3P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

443254:MARPI RS05415
gene id: 443254:MARPI_RS05415
uniprot id: H2J822
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

443254:MARPI RS03265
gene id: 443254:MARPI_RS03265
uniprot id: H2J640
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

443254:MARPI RS04530
gene id: 443254:MARPI_RS04530
uniprot id: H2J7E5
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS07895
gene id: 443254:MARPI_RS07895
uniprot id: H2J4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

443254:MARPI RS08200
gene id: 443254:MARPI_RS08200
uniprot id: H2J543
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

443254:MARPI RS05685
gene id: 443254:MARPI_RS05685
uniprot id: H2J881
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

443254:MARPI RS04670
gene id: 443254:MARPI_RS04670
uniprot id: H2J7M5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

443254:MARPI RS07945
gene id: 443254:MARPI_RS07945
uniprot id: H2J4Y9
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS08945
gene id: 443254:MARPI_RS08945
uniprot id: H2J5X9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

443254:MARPI RS03050
gene id: 443254:MARPI_RS03050
uniprot id: H2J5S3
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS01155
gene id: 443254:MARPI_RS01155
uniprot id: H2J3P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

443254:MARPI RS09105
gene id: 443254:MARPI_RS09105
uniprot id: H2J682
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS08820
gene id: 443254:MARPI_RS08820
uniprot id: H2J5V4
names: Similarity
messages: Belongs to the bacterial flagellin family.

443254:MARPI RS04610
gene id: 443254:MARPI_RS04610
uniprot id: H2J7L5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

443254:MARPI RS05970
gene id: 443254:MARPI_RS05970
uniprot id: H2J8D8
names: Similarity
messages: Belongs to the peptidase M18 family.

443254:MARPI RS00750
gene id: 443254:MARPI_RS00750
uniprot id: H2J387
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS02465
gene id: 443254:MARPI_RS02465
uniprot id: H2J586
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS00715
gene id: 443254:MARPI_RS00715
uniprot id: H2J380
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

443254:MARPI RS07820
gene id: 443254:MARPI_RS07820
uniprot id: H2J4N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

443254:MARPI RS00130
gene id: 443254:MARPI_RS00130
uniprot id: H2J2P1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

443254:MARPI RS09700
gene id: 443254:MARPI_RS09700
uniprot id: H2J6R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS07850
gene id: 443254:MARPI_RS07850
uniprot id: H2J4P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

443254:MARPI RS07075
gene id: 443254:MARPI_RS07075
uniprot id: H2J3U1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

443254:MARPI RS08700
gene id: 443254:MARPI_RS08700
uniprot id: H2J5T3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

443254:MARPI RS03335
gene id: 443254:MARPI_RS03335
uniprot id: H2J654
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

443254:MARPI RS00825
gene id: 443254:MARPI_RS00825
uniprot id: H2J3H6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

443254:MARPI RS05370
gene id: 443254:MARPI_RS05370
uniprot id: H2J813
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

443254:MARPI RS10720
gene id: 443254:MARPI_RS10720
uniprot id: H2J7R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

443254:MARPI RS07335
gene id: 443254:MARPI_RS07335
uniprot id: H2J471
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

443254:MARPI RS00325
gene id: 443254:MARPI_RS00325
uniprot id: H2J2S8
names: Similarity
messages: Belongs to the UPF0111 family.

443254:MARPI RS09815
gene id: 443254:MARPI_RS09815
uniprot id: H2J6T5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

443254:MARPI RS06015
gene id: 443254:MARPI_RS06015
uniprot id: H2J8E7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS09730
gene id: 443254:MARPI_RS09730
uniprot id: H2J6S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

443254:MARPI RS03555
gene id: 443254:MARPI_RS03555
uniprot id: H2J6H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

443254:MARPI RS04265
gene id: 443254:MARPI_RS04265
uniprot id: H2J791
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

443254:MARPI RS06265
gene id: 443254:MARPI_RS06265
uniprot id: H2J2Y9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

443254:MARPI RS03165
gene id: 443254:MARPI_RS03165
uniprot id: H2J620
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS02865
gene id: 443254:MARPI_RS02865
uniprot id: H2J5N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

443254:MARPI RS06045
gene id: 443254:MARPI_RS06045
uniprot id: H2J8F3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

443254:MARPI RS02490
gene id: 443254:MARPI_RS02490
uniprot id: H2J591
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

443254:MARPI RS01180
gene id: 443254:MARPI_RS01180
uniprot id: H2J3P6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

443254:MARPI RS02390
gene id: 443254:MARPI_RS02390
uniprot id: H2J572
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS01375
gene id: 443254:MARPI_RS01375
uniprot id: H2J401
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

443254:MARPI RS01290
gene id: 443254:MARPI_RS01290
uniprot id: H2J3Y4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

443254:MARPI RS02820
gene id: 443254:MARPI_RS02820
uniprot id: H2J5M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

443254:MARPI RS04660
gene id: 443254:MARPI_RS04660
uniprot id: H2J7M3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

443254:MARPI RS09890
gene id: 443254:MARPI_RS09890
uniprot id: H2J711
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

443254:MARPI RS02705
gene id: 443254:MARPI_RS02705
uniprot id: H2J5K5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

443254:MARPI RS04635
gene id: 443254:MARPI_RS04635
uniprot id: H2J7L8
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS01890
gene id: 443254:MARPI_RS01890
uniprot id: H2J4H4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

443254:MARPI RS04350
gene id: 443254:MARPI_RS04350
uniprot id: H2J7A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

443254:MARPI RS07740
gene id: 443254:MARPI_RS07740
uniprot id: H2J4M2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

443254:MARPI RS07220
gene id: 443254:MARPI_RS07220
uniprot id: H2J448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS04295
gene id: 443254:MARPI_RS04295
uniprot id: H2J797
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

443254:MARPI RS10125
gene id: 443254:MARPI_RS10125
uniprot id: H2J758
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

443254:MARPI RS04455
gene id: 443254:MARPI_RS04455
uniprot id: H2J7C9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

443254:MARPI RS09515
gene id: 443254:MARPI_RS09515
uniprot id: H2J6M9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

443254:MARPI RS02255
gene id: 443254:MARPI_RS02255
uniprot id: H2J4W8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

443254:MARPI RS05325
gene id: 443254:MARPI_RS05325
uniprot id: H2J805
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

443254:MARPI RS09185
gene id: 443254:MARPI_RS09185
uniprot id: H2J698
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

443254:MARPI RS09445
gene id: 443254:MARPI_RS09445
uniprot id: H2J6E8
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS01265
gene id: 443254:MARPI_RS01265
uniprot id: H2J3X9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS03210
gene id: 443254:MARPI_RS03210
uniprot id: H2J629
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

443254:MARPI RS01380
gene id: 443254:MARPI_RS01380
uniprot id: H2J402
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

443254:MARPI RS04335
gene id: 443254:MARPI_RS04335
uniprot id: H2J7A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

443254:MARPI RS04235
gene id: 443254:MARPI_RS04235
uniprot id: H2J785
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

443254:MARPI RS03820
gene id: 443254:MARPI_RS03820
uniprot id: H2J6U0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

443254:MARPI RS08725
gene id: 443254:MARPI_RS08725
uniprot id: H2J5T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

443254:MARPI RS03600
gene id: 443254:MARPI_RS03600
uniprot id: H2J6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

443254:MARPI RS00885
gene id: 443254:MARPI_RS00885
uniprot id: H2J3I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS03270
gene id: 443254:MARPI_RS03270
uniprot id: H2J641
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

443254:MARPI RS04215
gene id: 443254:MARPI_RS04215
uniprot id: H2J781
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

443254:MARPI RS04110
gene id: 443254:MARPI_RS04110
uniprot id: H2J6Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS01040
gene id: 443254:MARPI_RS01040
uniprot id: H2J3L8
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS05030
gene id: 443254:MARPI_RS05030
uniprot id: H2J7U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS07715
gene id: 443254:MARPI_RS07715
uniprot id: H2J4L7
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

443254:MARPI RS04000
gene id: 443254:MARPI_RS04000
uniprot id: H2J6X2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

443254:MARPI RS07985
gene id: 443254:MARPI_RS07985
uniprot id: H2J4Z7
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS07885
gene id: 443254:MARPI_RS07885
uniprot id: H2J4Q1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

443254:MARPI RS03865
gene id: 443254:MARPI_RS03865
uniprot id: H2J6U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

443254:MARPI RS08435
gene id: 443254:MARPI_RS08435
uniprot id: H2J5F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

443254:MARPI RS03750
gene id: 443254:MARPI_RS03750
uniprot id: H2J6K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

443254:MARPI RS05140
gene id: 443254:MARPI_RS05140
uniprot id: H2J7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS09415
gene id: 443254:MARPI_RS09415
uniprot id: H2J6E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

443254:MARPI RS02210
gene id: 443254:MARPI_RS02210
uniprot id: H2J4V8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

443254:MARPI RS07225
gene id: 443254:MARPI_RS07225
uniprot id: H2J449
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

443254:MARPI RS07030
gene id: 443254:MARPI_RS07030
uniprot id: H2J3T2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

443254:MARPI RS04380
gene id: 443254:MARPI_RS04380
uniprot id: H2J7B4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

443254:MARPI RS05670
gene id: 443254:MARPI_RS05670
uniprot id: H2J871
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

443254:MARPI RS10845
gene id: 443254:MARPI_RS10845
uniprot id: H2J6M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

443254:MARPI RS00520
gene id: 443254:MARPI_RS00520
uniprot id: H2J341
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

443254:MARPI RS04320
gene id: 443254:MARPI_RS04320
uniprot id: H2J7A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

443254:MARPI RS07450
gene id: 443254:MARPI_RS07450
uniprot id: H2J495
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

443254:MARPI RS04025
gene id: 443254:MARPI_RS04025
uniprot id: H2J6X7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

443254:MARPI RS10560
gene id: 443254:MARPI_RS10560
uniprot id: H2J337
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

443254:MARPI RS09310
gene id: 443254:MARPI_RS09310
uniprot id: H2J6C2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

443254:MARPI RS07530
gene id: 443254:MARPI_RS07530
uniprot id: H2J4B1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

443254:MARPI RS07060
gene id: 443254:MARPI_RS07060
uniprot id: H2J3T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

443254:MARPI RS06255
gene id: 443254:MARPI_RS06255
uniprot id: H2J2Y7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

443254:MARPI RS06720
gene id: 443254:MARPI_RS06720
uniprot id: H2J3F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

443254:MARPI RS10155
gene id: 443254:MARPI_RS10155
uniprot id: H2J764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

443254:MARPI RS04250
gene id: 443254:MARPI_RS04250
uniprot id: H2J788
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

443254:MARPI RS09360
gene id: 443254:MARPI_RS09360
uniprot id: H2J6D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

443254:MARPI RS09500
gene id: 443254:MARPI_RS09500
uniprot id: H2J6M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

443254:MARPI RS07270
gene id: 443254:MARPI_RS07270
uniprot id: H2J458
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

443254:MARPI RS09420
gene id: 443254:MARPI_RS09420
uniprot id: H2J6E3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

443254:MARPI RS09750
gene id: 443254:MARPI_RS09750
uniprot id: H2J6S4
names: Similarity
messages: Belongs to the citrate synthase family.

443254:MARPI RS00010
gene id: 443254:MARPI_RS00010
uniprot id: H2J873
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

443254:MARPI RS08710
gene id: 443254:MARPI_RS08710
uniprot id: H2J5T5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

443254:MARPI RS01815
gene id: 443254:MARPI_RS01815
uniprot id: H2J4G2
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

443254:MARPI RS04735
gene id: 443254:MARPI_RS04735
uniprot id: H2J7N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS07400
gene id: 443254:MARPI_RS07400
uniprot id: H2J484
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

443254:MARPI RS04225
gene id: 443254:MARPI_RS04225
uniprot id: H2J783
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

443254:MARPI RS01955
gene id: 443254:MARPI_RS01955
uniprot id: H2J4Q8
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

443254:MARPI RS06395
gene id: 443254:MARPI_RS06395
uniprot id: H2J314
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

443254:MARPI RS09150
gene id: 443254:MARPI_RS09150
uniprot id: H2J691
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

443254:MARPI RS02385
gene id: 443254:MARPI_RS02385
uniprot id: H2J571
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS05540
gene id: 443254:MARPI_RS05540
uniprot id: H2J847
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

443254:MARPI RS07840
gene id: 443254:MARPI_RS07840
uniprot id: H2J4P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

443254:MARPI RS08685
gene id: 443254:MARPI_RS08685
uniprot id: H2J5T1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

443254:MARPI RS09825
gene id: 443254:MARPI_RS09825
uniprot id: H2J6T7
names: Similarity
messages: Belongs to the peptidase S1C family.

443254:MARPI RS07375
gene id: 443254:MARPI_RS07375
uniprot id: H2J479
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

443254:MARPI RS01855
gene id: 443254:MARPI_RS01855
uniprot id: H2J4G7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

443254:MARPI RS02150
gene id: 443254:MARPI_RS02150
uniprot id: H2J4U6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

443254:MARPI RS00355
gene id: 443254:MARPI_RS00355
uniprot id: H2J2T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

443254:MARPI RS05395
gene id: 443254:MARPI_RS05395
uniprot id: H2J818
names: Similarity
messages: Belongs to the UPF0473 family.

443254:MARPI RS00625
gene id: 443254:MARPI_RS00625
uniprot id: H2J363
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS00015
gene id: 443254:MARPI_RS00015
uniprot id: H2J874
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

443254:MARPI RS06870
gene id: 443254:MARPI_RS06870
uniprot id: H2J3Q5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

443254:MARPI RS02155
gene id: 443254:MARPI_RS02155
uniprot id: H2J4U7
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS06490
gene id: 443254:MARPI_RS06490
uniprot id: H2J3A8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

443254:MARPI RS03455
gene id: 443254:MARPI_RS03455
uniprot id: H2J6F4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

443254:MARPI RS08895
gene id: 443254:MARPI_RS08895
uniprot id: H2J5W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

443254:MARPI RS08425
gene id: 443254:MARPI_RS08425
uniprot id: H2J5F7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

443254:MARPI RS06065
gene id: 443254:MARPI_RS06065
uniprot id: H2J2V0
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS09055
gene id: 443254:MARPI_RS09055
uniprot id: H2J601
names: Similarity
messages: Belongs to the DEAD box helicase family.

443254:MARPI RS03850
gene id: 443254:MARPI_RS03850
uniprot id: H2J6U6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

443254:MARPI RS06480
gene id: 443254:MARPI_RS06480
uniprot id: H2J3A6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

443254:MARPI RS00570
gene id: 443254:MARPI_RS00570
uniprot id: H2J351
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Monomer.

443254:MARPI RS06650
gene id: 443254:MARPI_RS06650
uniprot id: H2J3E0
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS02595
gene id: 443254:MARPI_RS02595
uniprot id: H2J5B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS00465
gene id: 443254:MARPI_RS00465
uniprot id: H2J330
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

443254:MARPI RS01870
gene id: 443254:MARPI_RS01870
uniprot id: H2J4H0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

443254:MARPI RS09240
gene id: 443254:MARPI_RS09240
uniprot id: H2J6A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

443254:MARPI RS06610
gene id: 443254:MARPI_RS06610
uniprot id: H2J3D2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

443254:MARPI RS02645
gene id: 443254:MARPI_RS02645
uniprot id: H2J5C1
names: Subcellular Location Annotation
messages: Secreted

443254:MARPI RS00675
gene id: 443254:MARPI_RS00675
uniprot id: H2J372
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

443254:MARPI RS00480
gene id: 443254:MARPI_RS00480
uniprot id: H2J333
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

443254:MARPI RS02720
gene id: 443254:MARPI_RS02720
uniprot id: H2J5K8
names: Similarity
messages: Belongs to the UPF0047 family.

443254:MARPI RS02860
gene id: 443254:MARPI_RS02860
uniprot id: H2J5N6
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

443254:MARPI RS04340
gene id: 443254:MARPI_RS04340
uniprot id: H2J7A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

443254:MARPI RS06455
gene id: 443254:MARPI_RS06455
uniprot id: H2J3A1
names: Similarity
messages: Belongs to the UPF0758 family.

443254:MARPI RS07130
gene id: 443254:MARPI_RS07130
uniprot id: H2J3V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

443254:MARPI RS04770
gene id: 443254:MARPI_RS04770
uniprot id: H2J7P5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

443254:MARPI RS06800
gene id: 443254:MARPI_RS06800
uniprot id: H2J3G7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

443254:MARPI RS04680
gene id: 443254:MARPI_RS04680
uniprot id: H2J7M7
names: Similarity
messages: Belongs to the peptidase M20A family.

443254:MARPI RS02530
gene id: 443254:MARPI_RS02530
uniprot id: H2J599
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

443254:MARPI RS03020
gene id: 443254:MARPI_RS03020
uniprot id: H2J5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS05320
gene id: 443254:MARPI_RS05320
uniprot id: H2J804
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

443254:MARPI RS08995
gene id: 443254:MARPI_RS08995
uniprot id: H2J5Y9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

443254:MARPI RS06655
gene id: 443254:MARPI_RS06655
uniprot id: H2J3E1
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS04200
gene id: 443254:MARPI_RS04200
uniprot id: H2J778
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

443254:MARPI RS09465
gene id: 443254:MARPI_RS09465
uniprot id: H2J6L9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

443254:MARPI RS03125
gene id: 443254:MARPI_RS03125
uniprot id: H2J613
names: Similarity
messages: Belongs to the acylphosphatase family.

443254:MARPI RS02520
gene id: 443254:MARPI_RS02520
uniprot id: H2J597
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

443254:MARPI RS01055
gene id: 443254:MARPI_RS01055
uniprot id: H2J3L9
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS08045
gene id: 443254:MARPI_RS08045
uniprot id: H2J509
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

443254:MARPI RS03280
gene id: 443254:MARPI_RS03280
uniprot id: H2J643
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

443254:MARPI RS03220
gene id: 443254:MARPI_RS03220
uniprot id: H2J631
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

443254:MARPI RS03650
gene id: 443254:MARPI_RS03650
uniprot id: H2J6I7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

443254:MARPI RS08065
gene id: 443254:MARPI_RS08065
uniprot id: H2J513
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

443254:MARPI RS09110
gene id: 443254:MARPI_RS09110
uniprot id: H2J683
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

443254:MARPI RS04240
gene id: 443254:MARPI_RS04240
uniprot id: H2J786
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

443254:MARPI RS03185
gene id: 443254:MARPI_RS03185
uniprot id: H2J624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

443254:MARPI RS07110
gene id: 443254:MARPI_RS07110
uniprot id: H2J3U8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

443254:MARPI RS08325
gene id: 443254:MARPI_RS08325
uniprot id: H2J5E0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

443254:MARPI RS06910
gene id: 443254:MARPI_RS06910
uniprot id: H2J3R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

443254:MARPI RS01015
gene id: 443254:MARPI_RS01015
uniprot id: H2J3L3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

443254:MARPI RS05530
gene id: 443254:MARPI_RS05530
uniprot id: H2J845
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS01185
gene id: 443254:MARPI_RS01185
uniprot id: H2J3P7
names: Similarity
messages: Belongs to the asp23 family.

443254:MARPI RS08745
gene id: 443254:MARPI_RS08745
uniprot id: H2J5U2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

443254:MARPI RS03440
gene id: 443254:MARPI_RS03440
uniprot id: H2J675
names: Similarity
messages: Belongs to the BMP lipoprotein family.

443254:MARPI RS06780
gene id: 443254:MARPI_RS06780
uniprot id: H2J3G3
names: Similarity
messages: Belongs to the bacterial secretin family.

443254:MARPI RS00145
gene id: 443254:MARPI_RS00145
uniprot id: H2J2P4
names: Similarity
messages: Belongs to the AHA1 family.

443254:MARPI RS03150
gene id: 443254:MARPI_RS03150
uniprot id: H2J617
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

443254:MARPI RS09570
gene id: 443254:MARPI_RS09570
uniprot id: H2J6N8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS03170
gene id: 443254:MARPI_RS03170
uniprot id: H2J621
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

443254:MARPI RS01330
gene id: 443254:MARPI_RS01330
uniprot id: H2J3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

443254:MARPI RS04285
gene id: 443254:MARPI_RS04285
uniprot id: H2J795
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

443254:MARPI RS06940
gene id: 443254:MARPI_RS06940
uniprot id: H2J3R8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

443254:MARPI RS04180
gene id: 443254:MARPI_RS04180
uniprot id: H2J774
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS04645
gene id: 443254:MARPI_RS04645
uniprot id: H2J7M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS00605
gene id: 443254:MARPI_RS00605
uniprot id: H2J359
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

443254:MARPI RS01220
gene id: 443254:MARPI_RS01220
uniprot id: H2J3X0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

443254:MARPI RS09345
gene id: 443254:MARPI_RS09345
uniprot id: H2J6C9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

443254:MARPI RS06375
gene id: 443254:MARPI_RS06375
uniprot id: H2J310
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

443254:MARPI RS08770
gene id: 443254:MARPI_RS08770
uniprot id: H2J5U7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

443254:MARPI RS10660
gene id: 443254:MARPI_RS10660
uniprot id: H2J6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

443254:MARPI RS05580
gene id: 443254:MARPI_RS05580
uniprot id: H2J854
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

443254:MARPI RS07325
gene id: 443254:MARPI_RS07325
uniprot id: H2J469
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS09935
gene id: 443254:MARPI_RS09935
uniprot id: H2J720
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

443254:MARPI RS06840
gene id: 443254:MARPI_RS06840
uniprot id: H2J3P9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

443254:MARPI RS05895
gene id: 443254:MARPI_RS05895
uniprot id: H2J8C3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS07795
gene id: 443254:MARPI_RS07795
uniprot id: H2J4N3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

443254:MARPI RS06020
gene id: 443254:MARPI_RS06020
uniprot id: H2J8E8
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

443254:MARPI RS07255
gene id: 443254:MARPI_RS07255
uniprot id: H2J455
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS04890
gene id: 443254:MARPI_RS04890
uniprot id: H2J7R9
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

443254:MARPI RS01900
gene id: 443254:MARPI_RS01900
uniprot id: H2J4H6
names: Similarity
messages: Belongs to the GARS family.

443254:MARPI RS00035
gene id: 443254:MARPI_RS00035
uniprot id: H2J878
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS09200
gene id: 443254:MARPI_RS09200
uniprot id: H2J6A1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

443254:MARPI RS05165
gene id: 443254:MARPI_RS05165
uniprot id: H2J7X3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

443254:MARPI RS06630
gene id: 443254:MARPI_RS06630
uniprot id: H2J3D6
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS01260
gene id: 443254:MARPI_RS01260
uniprot id: H2J3X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

443254:MARPI RS07430
gene id: 443254:MARPI_RS07430
uniprot id: H2J492
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

443254:MARPI RS07845
gene id: 443254:MARPI_RS07845
uniprot id: H2J4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

443254:MARPI RS01780
gene id: 443254:MARPI_RS01780
uniprot id: H2J4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

443254:MARPI RS06755
gene id: 443254:MARPI_RS06755
uniprot id: H2J3F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

443254:MARPI RS02535
gene id: 443254:MARPI_RS02535
uniprot id: H2J5A0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

443254:MARPI RS04655
gene id: 443254:MARPI_RS04655
uniprot id: H2J7M2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

443254:MARPI RS08410
gene id: 443254:MARPI_RS08410
uniprot id: H2J5F4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

443254:MARPI RS02835
gene id: 443254:MARPI_RS02835
uniprot id: H2J5N1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

443254:MARPI RS02460
gene id: 443254:MARPI_RS02460
uniprot id: H2J585
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

443254:MARPI RS04730
gene id: 443254:MARPI_RS04730
uniprot id: H2J7N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS00905
gene id: 443254:MARPI_RS00905
uniprot id: H2J3J1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

443254:MARPI RS03985
gene id: 443254:MARPI_RS03985
uniprot id: H2J6W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

443254:MARPI RS09940
gene id: 443254:MARPI_RS09940
uniprot id: H2J721
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

443254:MARPI RS07115
gene id: 443254:MARPI_RS07115
uniprot id: H2J3U9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

443254:MARPI RS06380
gene id: 443254:MARPI_RS06380
uniprot id: H2J311
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

443254:MARPI RS02970
gene id: 443254:MARPI_RS02970
uniprot id: H2J5Q7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

443254:MARPI RS00740
gene id: 443254:MARPI_RS00740
uniprot id: H2J385
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

443254:MARPI RS05590
gene id: 443254:MARPI_RS05590
uniprot id: H2J856
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS00085
gene id: 443254:MARPI_RS00085
uniprot id: H2J2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

443254:MARPI RS04315
gene id: 443254:MARPI_RS04315
uniprot id: H2J7A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

443254:MARPI RS03890
gene id: 443254:MARPI_RS03890
uniprot id: H2J6V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS03070
gene id: 443254:MARPI_RS03070
uniprot id: H2J5S7
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

443254:MARPI RS06435
gene id: 443254:MARPI_RS06435
uniprot id: H2J322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

443254:MARPI RS00765
gene id: 443254:MARPI_RS00765
uniprot id: H2J390
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

443254:MARPI RS09615
gene id: 443254:MARPI_RS09615
uniprot id: H2J6P7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

443254:MARPI RS02785
gene id: 443254:MARPI_RS02785
uniprot id: H2J5M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

443254:MARPI RS04280
gene id: 443254:MARPI_RS04280
uniprot id: H2J794
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

443254:MARPI RS00420
gene id: 443254:MARPI_RS00420
uniprot id: H2J2U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS06660
gene id: 443254:MARPI_RS06660
uniprot id: H2J3E2
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS06860
gene id: 443254:MARPI_RS06860
uniprot id: H2J3Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

443254:MARPI RS07195
gene id: 443254:MARPI_RS07195
uniprot id: H2J443
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

443254:MARPI RS06385
gene id: 443254:MARPI_RS06385
uniprot id: H2J312
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

443254:MARPI RS01150
gene id: 443254:MARPI_RS01150
uniprot id: H2J3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

443254:MARPI RS05700
gene id: 443254:MARPI_RS05700
uniprot id: H2J885
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS01875
gene id: 443254:MARPI_RS01875
uniprot id: H2J4H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

443254:MARPI RS00380
gene id: 443254:MARPI_RS00380
uniprot id: H2J2T9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

443254:MARPI RS07245
gene id: 443254:MARPI_RS07245
uniprot id: H2J453
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS02515
gene id: 443254:MARPI_RS02515
uniprot id: H2J596
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

443254:MARPI RS00295
gene id: 443254:MARPI_RS00295
uniprot id: H2J2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

443254:MARPI RS09675
gene id: 443254:MARPI_RS09675
uniprot id: H2J6Q9
names: Similarity
messages: Belongs to the peptidase S13 family.

443254:MARPI RS08150
gene id: 443254:MARPI_RS08150
uniprot id: H2J532
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

443254:MARPI RS01810
gene id: 443254:MARPI_RS01810
uniprot id: H2J4G1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443254:MARPI RS01980
gene id: 443254:MARPI_RS01980
uniprot id: H2J4R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

443254:MARPI RS09580
gene id: 443254:MARPI_RS09580
uniprot id: H2J6P0
names: Similarity
messages: Belongs to the archease family.

443254:MARPI RS00250
gene id: 443254:MARPI_RS00250
uniprot id: H2J2R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

443254:MARPI RS08940
gene id: 443254:MARPI_RS08940
uniprot id: H2J5X8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

443254:MARPI RS03920
gene id: 443254:MARPI_RS03920
uniprot id: H2J6V6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

443254:MARPI RS10205
gene id: 443254:MARPI_RS10205
uniprot id: H2J7F1
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS07645
gene id: 443254:MARPI_RS07645
uniprot id: H2J4K3
names: Similarity
messages: Belongs to the RemA family.

443254:MARPI RS00705
gene id: 443254:MARPI_RS00705
uniprot id: H2J378
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

443254:MARPI RS02580
gene id: 443254:MARPI_RS02580
uniprot id: H2J5A8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

443254:MARPI RS02855
gene id: 443254:MARPI_RS02855
uniprot id: H2J5N5
names: Similarity
messages: Belongs to the aspartokinase family.

443254:MARPI RS01145
gene id: 443254:MARPI_RS01145
uniprot id: H2J3N9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

443254:MARPI RS07435
gene id: 443254:MARPI_RS07435
uniprot id: H2J493
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443254:MARPI RS04740
gene id: 443254:MARPI_RS04740
uniprot id: H2J7N9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

443254:MARPI RS02440
gene id: 443254:MARPI_RS02440
uniprot id: H2J581
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

443254:MARPI RS03930
gene id: 443254:MARPI_RS03930
uniprot id: H2J6V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

443254:MARPI RS06300
gene id: 443254:MARPI_RS06300
uniprot id: H2J2Z6
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS05360
gene id: 443254:MARPI_RS05360
uniprot id: H2J811
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

443254:MARPI RS02710
gene id: 443254:MARPI_RS02710
uniprot id: H2J5K6
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

443254:MARPI RS09355
gene id: 443254:MARPI_RS09355
uniprot id: H2J6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

443254:MARPI RS09490
gene id: 443254:MARPI_RS09490
uniprot id: H2J6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

443254:MARPI RS05855
gene id: 443254:MARPI_RS05855
uniprot id: H2J8B6
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

443254:MARPI RS09425
gene id: 443254:MARPI_RS09425
uniprot id: H2J6E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

443254:MARPI RS01195
gene id: 443254:MARPI_RS01195
uniprot id: H2J3W5
names: Similarity
messages: Belongs to the peptidase M24B family.

443254:MARPI RS06140
gene id: 443254:MARPI_RS06140
uniprot id: H2J2W5
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS10440
gene id: 443254:MARPI_RS10440
uniprot id: H2J7J6
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS10105
gene id: 443254:MARPI_RS10105
uniprot id: H2J754
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS06640
gene id: 443254:MARPI_RS06640
uniprot id: H2J3D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

443254:MARPI RS09205
gene id: 443254:MARPI_RS09205
uniprot id: H2J6A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

443254:MARPI RS10020
gene id: 443254:MARPI_RS10020
uniprot id: H2J737
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS03835
gene id: 443254:MARPI_RS03835
uniprot id: H2J6U3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

443254:MARPI RS08750
gene id: 443254:MARPI_RS08750
uniprot id: H2J5U3
names: Subcellular Location Annotation
messages: Cytoplasm

443254:MARPI RS02525
gene id: 443254:MARPI_RS02525
uniprot id: H2J598
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

443254:MARPI RS00650
gene id: 443254:MARPI_RS00650
uniprot id: H2J368
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

443254:MARPI RS01165
gene id: 443254:MARPI_RS01165
uniprot id: H2J3P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

443254:MARPI RS05610
gene id: 443254:MARPI_RS05610
uniprot id: H2J860
names: Similarity
messages: Belongs to the AOR/FOR family.

443254:MARPI RS08640
gene id: 443254:MARPI_RS08640
uniprot id: H2J5K0
names: Similarity
messages: Belongs to the glutamine synthetase family.

443254:MARPI RS10435
gene id: 443254:MARPI_RS10435
uniprot id: H2J7J5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

443254:MARPI RS07090
gene id: 443254:MARPI_RS07090
uniprot id: H2J3U4
names: Similarity
messages: Belongs to the DprA/Smf family.

443254:MARPI RS02380
gene id: 443254:MARPI_RS02380
uniprot id: H2J570
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443254:MARPI RS07500
gene id: 443254:MARPI_RS07500
uniprot id: H2J4A5
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS01335
gene id: 443254:MARPI_RS01335
uniprot id: H2J3Z3
names: Similarity
messages: Belongs to the GSP E family.

443254:MARPI RS09050
gene id: 443254:MARPI_RS09050
uniprot id: H2J600
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

443254:MARPI RS03895
gene id: 443254:MARPI_RS03895
uniprot id: H2J6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443254:MARPI RS03040
gene id: 443254:MARPI_RS03040
uniprot id: H2J5S1
names: Subcellular Location Annotation
messages: Membrane

443254:MARPI RS04255
gene id: 443254:MARPI_RS04255
uniprot id: H2J789
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

443254:MARPI RS09130
gene id: 443254:MARPI_RS09130
uniprot id: H2J687
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

443254:MARPI RS06360
gene id: 443254:MARPI_RS06360
uniprot id: H2J307
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

443254:MARPI RS00215
gene id: 443254:MARPI_RS00215
uniprot id: H2J2Q7
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

443254:MARPI RS10405
gene id: 443254:MARPI_RS10405
uniprot id: H2J7J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

443254:MARPI RS03705
gene id: 443254:MARPI_RS03705
uniprot id: H2J6J8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

443254:MARPI RS02375
gene id: 443254:MARPI_RS02375
uniprot id: H2J569
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

443254:MARPI RS03375
gene id: 443254:MARPI_RS03375
uniprot id: H2J662
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

443254:MARPI RS06280
gene id: 443254:MARPI_RS06280
uniprot id: H2J2Z2
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

443254:MARPI RS08030
gene id: 443254:MARPI_RS08030
uniprot id: H2J506
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

443254:MARPI RS08900
gene id: 443254:MARPI_RS08900
uniprot id: H2J5X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

443254:MARPI RS03785
gene id: 443254:MARPI_RS03785
uniprot id: H2J6L4
names: Similarity
messages: Belongs to the peptidase C1 family.

443254:MARPI RS05960
gene id: 443254:MARPI_RS05960
uniprot id: H2J8D6
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

443254:MARPI RS05270
gene id: 443254:MARPI_RS05270
uniprot id: H2J7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

443254:MARPI RS06350
gene id: 443254:MARPI_RS06350
uniprot id: H2J305
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

443254:MARPI RS06145
gene id: 443254:MARPI_RS06145
uniprot id: H2J2W6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.