443218:AS9A RS16050
gene id: 443218:AS9A_RS16050
uniprot id: F6EPW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

443218:AS9A RS15735
gene id: 443218:AS9A_RS15735
uniprot id: F6EP55
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

443218:AS9A RS10780
gene id: 443218:AS9A_RS10780
uniprot id: F6EQZ0
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS08360
gene id: 443218:AS9A_RS08360
uniprot id: F6EKP6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS20925
gene id: 443218:AS9A_RS20925
uniprot id: F6EM30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

443218:AS9A RS17100
gene id: 443218:AS9A_RS17100
uniprot id: F6ERD5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

443218:AS9A RS16630
gene id: 443218:AS9A_RS16630
uniprot id: F6EQN8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

443218:AS9A RS11720
gene id: 443218:AS9A_RS11720
uniprot id: F6EET0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

443218:AS9A RS06120
gene id: 443218:AS9A_RS06120
uniprot id: F6EEL6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

443218:AS9A RS01100
gene id: 443218:AS9A_RS01100
uniprot id: F6EFA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

443218:AS9A RS03185
gene id: 443218:AS9A_RS03185
uniprot id: F6EKD7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

443218:AS9A RS01135
gene id: 443218:AS9A_RS01135
uniprot id: F6EFB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

443218:AS9A RS20025
gene id: 443218:AS9A_RS20025
uniprot id: F6EK78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

443218:AS9A RS18210
gene id: 443218:AS9A_RS18210
uniprot id: F6EFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

443218:AS9A RS00655
gene id: 443218:AS9A_RS00655
uniprot id: F6EEE1
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

443218:AS9A RS15145
gene id: 443218:AS9A_RS15145
uniprot id: F6EMN7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

443218:AS9A RS04130
gene id: 443218:AS9A_RS04130
uniprot id: F6EM98
names: Similarity
messages: Belongs to the citrate synthase family.

443218:AS9A RS05480
gene id: 443218:AS9A_RS05480
uniprot id: F6EQX2
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

443218:AS9A RS19485
gene id: 443218:AS9A_RS19485
uniprot id: F6EJ92
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS15050
gene id: 443218:AS9A_RS15050
uniprot id: F6EML8
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS21695
gene id: 443218:AS9A_RS21695
uniprot id: F6ENW4
names: Cofactor
messages: Binds 1 FAD per subunit.

443218:AS9A RS15125
gene id: 443218:AS9A_RS15125
uniprot id: F6EMN3
names: Similarity
messages: Belongs to the acylphosphatase family.

443218:AS9A RS03755
gene id: 443218:AS9A_RS03755
uniprot id: F6ELD2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443218:AS9A RS22260
gene id: 443218:AS9A_RS22260
uniprot id: F6ESJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

443218:AS9A RS20805
gene id: 443218:AS9A_RS20805
uniprot id: F6EM03
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS14510
gene id: 443218:AS9A_RS14510
uniprot id: F6EKY2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS06955
gene id: 443218:AS9A_RS06955
uniprot id: F6EH54
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

443218:AS9A RS21460
gene id: 443218:AS9A_RS21460
uniprot id: F6ENR5
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS12930
gene id: 443218:AS9A_RS12930
uniprot id: F6EHF7
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS08800
gene id: 443218:AS9A_RS08800
uniprot id: F6ELM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

443218:AS9A RS17360
gene id: 443218:AS9A_RS17360
uniprot id: F6ES59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

443218:AS9A RS19045
gene id: 443218:AS9A_RS19045
uniprot id: F6EIC7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

443218:AS9A RS10335
gene id: 443218:AS9A_RS10335
uniprot id: F6EPV5
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS13120
gene id: 443218:AS9A_RS13120
uniprot id: F6EI68
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

443218:AS9A RS07595
gene id: 443218:AS9A_RS07595
uniprot id: F6EIV9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

443218:AS9A RS06305
gene id: 443218:AS9A_RS06305
uniprot id: F6EFD9
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

443218:AS9A RS02175
gene id: 443218:AS9A_RS02175
uniprot id: F6EHV2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

443218:AS9A RS21655
gene id: 443218:AS9A_RS21655
uniprot id: F6ENV6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

443218:AS9A RS18185
gene id: 443218:AS9A_RS18185
uniprot id: F6EFW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

443218:AS9A RS17050
gene id: 443218:AS9A_RS17050
uniprot id: F6ERC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

443218:AS9A RS02200
gene id: 443218:AS9A_RS02200
uniprot id: F6EHV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

443218:AS9A RS02320
gene id: 443218:AS9A_RS02320
uniprot id: F6EIK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

443218:AS9A RS00905
gene id: 443218:AS9A_RS00905
uniprot id: F6EF66
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

443218:AS9A RS20255
gene id: 443218:AS9A_RS20255
uniprot id: F6EL05
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS14235
gene id: 443218:AS9A_RS14235
uniprot id: F6EKS7
names: Similarity
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

443218:AS9A RS17085
gene id: 443218:AS9A_RS17085
uniprot id: F6ERD1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

443218:AS9A RS19865
gene id: 443218:AS9A_RS19865
uniprot id: F6EK46
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

443218:AS9A RS02390
gene id: 443218:AS9A_RS02390
uniprot id: F6EIM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

443218:AS9A RS12155
gene id: 443218:AS9A_RS12155
uniprot id: F6EFP0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

443218:AS9A RS19215
gene id: 443218:AS9A_RS19215
uniprot id: F6EIG3
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS15170
gene id: 443218:AS9A_RS15170
uniprot id: F6EMP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

443218:AS9A RS09155
gene id: 443218:AS9A_RS09155
uniprot id: F6EMI2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

443218:AS9A RS08910
gene id: 443218:AS9A_RS08910
uniprot id: F6EMD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

443218:AS9A RS17450
gene id: 443218:AS9A_RS17450
uniprot id: F6ES78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

443218:AS9A RS04110
gene id: 443218:AS9A_RS04110
uniprot id: F6EM94
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

443218:AS9A RS18830
gene id: 443218:AS9A_RS18830
uniprot id: F6EHK7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS18060
gene id: 443218:AS9A_RS18060
uniprot id: F6EFU2
names: Similarity
messages: Belongs to the DEAD box helicase family.

443218:AS9A RS10700
gene id: 443218:AS9A_RS10700
uniprot id: F6EQH7
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS04850
gene id: 443218:AS9A_RS04850
uniprot id: F6EPM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS02160
gene id: 443218:AS9A_RS02160
uniprot id: F6EHU9
names: Similarity
messages: Belongs to the AccD/PCCB family.

443218:AS9A RS08865
gene id: 443218:AS9A_RS08865
uniprot id: F6EMC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

443218:AS9A RS02210
gene id: 443218:AS9A_RS02210
uniprot id: F6EHW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

443218:AS9A RS02360
gene id: 443218:AS9A_RS02360
uniprot id: F6EIL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

443218:AS9A RS18200
gene id: 443218:AS9A_RS18200
uniprot id: F6EFX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

443218:AS9A RS21640
gene id: 443218:AS9A_RS21640
uniprot id: F6ENV3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

443218:AS9A RS10770
gene id: 443218:AS9A_RS10770
uniprot id: F6EQY8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS11805
gene id: 443218:AS9A_RS11805
uniprot id: F6EEU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

443218:AS9A RS00700
gene id: 443218:AS9A_RS00700
uniprot id: F6EEF0
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS13390
gene id: 443218:AS9A_RS13390
uniprot id: F6EIC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

443218:AS9A RS03665
gene id: 443218:AS9A_RS03665
uniprot id: F6ELB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

443218:AS9A RS16270
gene id: 443218:AS9A_RS16270
uniprot id: F6EQ16
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

443218:AS9A RS15025
gene id: 443218:AS9A_RS15025
uniprot id: F6EML2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

443218:AS9A RS00865
gene id: 443218:AS9A_RS00865
uniprot id: F6EF59
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

443218:AS9A RS15020
gene id: 443218:AS9A_RS15020
uniprot id: F6EML1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

443218:AS9A RS18535
gene id: 443218:AS9A_RS18535
uniprot id: F6EGS0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS04605
gene id: 443218:AS9A_RS04605
uniprot id: F6EPH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS07285
gene id: 443218:AS9A_RS07285
uniprot id: F6EI12
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

443218:AS9A RS00295
gene id: 443218:AS9A_RS00295
uniprot id: F6ERJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

443218:AS9A RS02485
gene id: 443218:AS9A_RS02485
uniprot id: F6EIP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

443218:AS9A RS03485
gene id: 443218:AS9A_RS03485
uniprot id: F6EL75
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS11225
gene id: 443218:AS9A_RS11225
uniprot id: F6ERW0
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS15435
gene id: 443218:AS9A_RS15435
uniprot id: F6ENI4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

443218:AS9A RS02925
gene id: 443218:AS9A_RS02925
uniprot id: F6EJK5
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS05740
gene id: 443218:AS9A_RS05740
uniprot id: F6ERQ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

443218:AS9A RS07445
gene id: 443218:AS9A_RS07445
uniprot id: F6EI41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS01815
gene id: 443218:AS9A_RS01815
uniprot id: F6ESC4
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

443218:AS9A RS07655
gene id: 443218:AS9A_RS07655
uniprot id: F6EIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

443218:AS9A RS01960
gene id: 443218:AS9A_RS01960
uniprot id: F6EHR0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

443218:AS9A RS05500
gene id: 443218:AS9A_RS05500
uniprot id: F6EQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

443218:AS9A RS03345
gene id: 443218:AS9A_RS03345
uniprot id: F6EKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

443218:AS9A RS18415
gene id: 443218:AS9A_RS18415
uniprot id: F6EGP4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

443218:AS9A RS15670
gene id: 443218:AS9A_RS15670
uniprot id: F6ENN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

443218:AS9A RS17265
gene id: 443218:AS9A_RS17265
uniprot id: F6ES41
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS16945
gene id: 443218:AS9A_RS16945
uniprot id: F6ERA2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

443218:AS9A RS03060
gene id: 443218:AS9A_RS03060
uniprot id: F6EJN2
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

443218:AS9A RS17415
gene id: 443218:AS9A_RS17415
uniprot id: F6ES70
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

443218:AS9A RS18745
gene id: 443218:AS9A_RS18745
uniprot id: F6EHI8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

443218:AS9A RS01475
gene id: 443218:AS9A_RS01475
uniprot id: F6EG58
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS01805
gene id: 443218:AS9A_RS01805
uniprot id: F6EH06
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS15070
gene id: 443218:AS9A_RS15070
uniprot id: F6EMM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

443218:AS9A RS07640
gene id: 443218:AS9A_RS07640
uniprot id: F6EIW9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

443218:AS9A RS14365
gene id: 443218:AS9A_RS14365
uniprot id: F6EKV3
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS19195
gene id: 443218:AS9A_RS19195
uniprot id: F6EIF8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

443218:AS9A RS12020
gene id: 443218:AS9A_RS12020
uniprot id: F6EFL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS19450
gene id: 443218:AS9A_RS19450
uniprot id: F6EJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

443218:AS9A RS05790
gene id: 443218:AS9A_RS05790
uniprot id: F6ERS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

443218:AS9A RS14930
gene id: 443218:AS9A_RS14930
uniprot id: F6ELV3
names: Similarity
messages: Belongs to the fructosamine kinase family.

443218:AS9A RS01090
gene id: 443218:AS9A_RS01090
uniprot id: F6EFA3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

443218:AS9A RS06475
gene id: 443218:AS9A_RS06475
uniprot id: F6EFH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

443218:AS9A RS08455
gene id: 443218:AS9A_RS08455
uniprot id: F6ELF3
names: Similarity
messages: Belongs to the histone deacetylase family.

443218:AS9A RS14950
gene id: 443218:AS9A_RS14950
uniprot id: F6EMJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS07215
gene id: 443218:AS9A_RS07215
uniprot id: F6EHZ8
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS02415
gene id: 443218:AS9A_RS02415
uniprot id: F6EIM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

443218:AS9A RS08365
gene id: 443218:AS9A_RS08365
uniprot id: F6EKP7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443218:AS9A RS01500
gene id: 443218:AS9A_RS01500
uniprot id: F6EG63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

443218:AS9A RS01525
gene id: 443218:AS9A_RS01525
uniprot id: F6EG68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

443218:AS9A RS02400
gene id: 443218:AS9A_RS02400
uniprot id: F6EIM4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

443218:AS9A RS09660
gene id: 443218:AS9A_RS09660
uniprot id: F6ENX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

443218:AS9A RS10035
gene id: 443218:AS9A_RS10035
uniprot id: F6EPP3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

443218:AS9A RS17720
gene id: 443218:AS9A_RS17720
uniprot id: F6EEZ9
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS04385
gene id: 443218:AS9A_RS04385
uniprot id: F6EN40
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS17355
gene id: 443218:AS9A_RS17355
uniprot id: F6ES58
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

443218:AS9A RS03890
gene id: 443218:AS9A_RS03890
uniprot id: F6EM45
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

443218:AS9A RS12990
gene id: 443218:AS9A_RS12990
uniprot id: F6EHG9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

443218:AS9A RS02420
gene id: 443218:AS9A_RS02420
uniprot id: F6EIM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

443218:AS9A RS16675
gene id: 443218:AS9A_RS16675
uniprot id: F6EQP7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS12305
gene id: 443218:AS9A_RS12305
uniprot id: F6EGE6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

443218:AS9A RS01480
gene id: 443218:AS9A_RS01480
uniprot id: F6EG59
names: Similarity
messages: Belongs to the peptidase M1 family.

443218:AS9A RS11340
gene id: 443218:AS9A_RS11340
uniprot id: F6ERY4
names: Similarity
messages: Belongs to the YciI family.

443218:AS9A RS07495
gene id: 443218:AS9A_RS07495
uniprot id: F6EIT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

443218:AS9A RS07710
gene id: 443218:AS9A_RS07710
uniprot id: F6EIY3
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS17730
gene id: 443218:AS9A_RS17730
uniprot id: F6EF01
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

443218:AS9A RS08170
gene id: 443218:AS9A_RS08170
uniprot id: F6EKK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

443218:AS9A RS12410
gene id: 443218:AS9A_RS12410
uniprot id: F6EGG9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

443218:AS9A RS10860
gene id: 443218:AS9A_RS10860
uniprot id: F6ER08
names: Similarity
messages: Belongs to the DSD1 family.

443218:AS9A RS10200
gene id: 443218:AS9A_RS10200
uniprot id: F6EPS8
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

443218:AS9A RS08555
gene id: 443218:AS9A_RS08555
uniprot id: F6ELH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

443218:AS9A RS17855
gene id: 443218:AS9A_RS17855
uniprot id: F6EF27
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

443218:AS9A RS01700
gene id: 443218:AS9A_RS01700
uniprot id: F6EGY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

443218:AS9A RS09220
gene id: 443218:AS9A_RS09220
uniprot id: F6EMJ4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

443218:AS9A RS19895
gene id: 443218:AS9A_RS19895
uniprot id: F6EK53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS09100
gene id: 443218:AS9A_RS09100
uniprot id: F6EMH1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

443218:AS9A RS17525
gene id: 443218:AS9A_RS17525
uniprot id: F6ES92
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

443218:AS9A RS07125
gene id: 443218:AS9A_RS07125
uniprot id: F6EH90
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS07815
gene id: 443218:AS9A_RS07815
uniprot id: F6EJP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

443218:AS9A RS06465
gene id: 443218:AS9A_RS06465
uniprot id: F6EFH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

443218:AS9A RS11290
gene id: 443218:AS9A_RS11290
uniprot id: F6ERX3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

443218:AS9A RS01445
gene id: 443218:AS9A_RS01445
uniprot id: F6EG52
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

443218:AS9A RS02505
gene id: 443218:AS9A_RS02505
uniprot id: F6EIP4
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS09600
gene id: 443218:AS9A_RS09600
uniprot id: F6ENF9
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

443218:AS9A RS02205
gene id: 443218:AS9A_RS02205
uniprot id: F6EHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

443218:AS9A RS07800
gene id: 443218:AS9A_RS07800
uniprot id: F6EJN8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

443218:AS9A RS05610
gene id: 443218:AS9A_RS05610
uniprot id: F6ERN2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

443218:AS9A RS19965
gene id: 443218:AS9A_RS19965
uniprot id: F6EK67
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS04575
gene id: 443218:AS9A_RS04575
uniprot id: F6EN80
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS08715
gene id: 443218:AS9A_RS08715
uniprot id: F6ELK3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS10130
gene id: 443218:AS9A_RS10130
uniprot id: F6EPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS18300
gene id: 443218:AS9A_RS18300
uniprot id: F6EGM1
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

443218:AS9A RS07245
gene id: 443218:AS9A_RS07245
uniprot id: F6EI04
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

443218:AS9A RS04370
gene id: 443218:AS9A_RS04370
uniprot id: F6EN37
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS11510
gene id: 443218:AS9A_RS11510
uniprot id: F6EEN5
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

443218:AS9A RS13010
gene id: 443218:AS9A_RS13010
uniprot id: F6EHH3
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS05045
gene id: 443218:AS9A_RS05045
uniprot id: F6EQ73
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

443218:AS9A RS06980
gene id: 443218:AS9A_RS06980
uniprot id: F6EH59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

443218:AS9A RS08585
gene id: 443218:AS9A_RS08585
uniprot id: F6ELI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

443218:AS9A RS09720
gene id: 443218:AS9A_RS09720
uniprot id: F6ENY9
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

443218:AS9A RS03530
gene id: 443218:AS9A_RS03530
uniprot id: F6EL85
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS17420
gene id: 443218:AS9A_RS17420
uniprot id: F6ES71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

443218:AS9A RS20205
gene id: 443218:AS9A_RS20205
uniprot id: F6EKZ5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

443218:AS9A RS10340
gene id: 443218:AS9A_RS10340
uniprot id: F6EPV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

443218:AS9A RS07620
gene id: 443218:AS9A_RS07620
uniprot id: F6EIW5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

443218:AS9A RS14105
gene id: 443218:AS9A_RS14105
uniprot id: F6EK23
names: Similarity
messages: Belongs to the cytochrome P450 family.

443218:AS9A RS03780
gene id: 443218:AS9A_RS03780
uniprot id: F6ELD7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS12015
gene id: 443218:AS9A_RS12015
uniprot id: F6EFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS09360
gene id: 443218:AS9A_RS09360
uniprot id: F6ENB2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

443218:AS9A RS09540
gene id: 443218:AS9A_RS09540
uniprot id: F6ENE7
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

443218:AS9A RS04050
gene id: 443218:AS9A_RS04050
uniprot id: F6EM79
names: Similarity
messages: Belongs to the MoaD family.

443218:AS9A RS03795
gene id: 443218:AS9A_RS03795
uniprot id: F6ELE0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS20060
gene id: 443218:AS9A_RS20060
uniprot id: F6EK87
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS02675
gene id: 443218:AS9A_RS02675
uniprot id: F6EIT0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

443218:AS9A RS12650
gene id: 443218:AS9A_RS12650
uniprot id: F6EH97
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS04900
gene id: 443218:AS9A_RS04900
uniprot id: F6EPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

443218:AS9A RS07260
gene id: 443218:AS9A_RS07260
uniprot id: F6EI07
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

443218:AS9A RS16645
gene id: 443218:AS9A_RS16645
uniprot id: F6EQP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

443218:AS9A RS00305
gene id: 443218:AS9A_RS00305
uniprot id: F6ERK1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

443218:AS9A RS01040
gene id: 443218:AS9A_RS01040
uniprot id: F6EF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

443218:AS9A RS16265
gene id: 443218:AS9A_RS16265
uniprot id: F6EQ15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

443218:AS9A RS19130
gene id: 443218:AS9A_RS19130
uniprot id: F6EIE3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443218:AS9A RS19480
gene id: 443218:AS9A_RS19480
uniprot id: F6EJ91
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS07585
gene id: 443218:AS9A_RS07585
uniprot id: F6EIV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

443218:AS9A RS05625
gene id: 443218:AS9A_RS05625
uniprot id: F6ERN6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS06865
gene id: 443218:AS9A_RS06865
uniprot id: F6EH35
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

443218:AS9A RS05020
gene id: 443218:AS9A_RS05020
uniprot id: F6EQ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

443218:AS9A RS10030
gene id: 443218:AS9A_RS10030
uniprot id: F6EPP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

443218:AS9A RS04500
gene id: 443218:AS9A_RS04500
uniprot id: F6EN65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

443218:AS9A RS09980
gene id: 443218:AS9A_RS09980
uniprot id: F6EP44
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS04670
gene id: 443218:AS9A_RS04670
uniprot id: F6EPI3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443218:AS9A RS21205
gene id: 443218:AS9A_RS21205
uniprot id: F6EMX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

443218:AS9A RS02470
gene id: 443218:AS9A_RS02470
uniprot id: F6EIN7
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS07300
gene id: 443218:AS9A_RS07300
uniprot id: F6EI15
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS04865
gene id: 443218:AS9A_RS04865
uniprot id: F6EPM3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

443218:AS9A RS22590
gene id: 443218:AS9A_RS22590
uniprot id: F6ERM6
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

443218:AS9A RS19170
gene id: 443218:AS9A_RS19170
uniprot id: F6EIF2
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS18835
gene id: 443218:AS9A_RS18835
uniprot id: F6EHK8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS15035
gene id: 443218:AS9A_RS15035
uniprot id: F6EML4
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

443218:AS9A RS02305
gene id: 443218:AS9A_RS02305
uniprot id: F6EHY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

443218:AS9A RS07955
gene id: 443218:AS9A_RS07955
uniprot id: F6EJS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

443218:AS9A RS01025
gene id: 443218:AS9A_RS01025
uniprot id: F6EF91
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

443218:AS9A RS02340
gene id: 443218:AS9A_RS02340
uniprot id: F6EIL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

443218:AS9A RS07850
gene id: 443218:AS9A_RS07850
uniprot id: F6EJQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

443218:AS9A RS21600
gene id: 443218:AS9A_RS21600
uniprot id: F6ENU5
names: Similarity
messages: Belongs to the YciI family.

443218:AS9A RS07960
gene id: 443218:AS9A_RS07960
uniprot id: F6EJS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

443218:AS9A RS08000
gene id: 443218:AS9A_RS08000
uniprot id: F6EJT1
names: Similarity
messages: Belongs to the peptidase C40 family.

443218:AS9A RS07515
gene id: 443218:AS9A_RS07515
uniprot id: F6EIU2
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS02315
gene id: 443218:AS9A_RS02315
uniprot id: F6EIK7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

443218:AS9A RS07540
gene id: 443218:AS9A_RS07540
uniprot id: F6EIU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS07995
gene id: 443218:AS9A_RS07995
uniprot id: F6EJS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS15495
gene id: 443218:AS9A_RS15495
uniprot id: F6ENJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

443218:AS9A RS20385
gene id: 443218:AS9A_RS20385
uniprot id: F6EL31
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS20940
gene id: 443218:AS9A_RS20940
uniprot id: F6EM33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.
messages: Cytoplasm

443218:AS9A RS03135
gene id: 443218:AS9A_RS03135
uniprot id: F6EKC7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

443218:AS9A RS07505
gene id: 443218:AS9A_RS07505
uniprot id: F6EIU0
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS21830
gene id: 443218:AS9A_RS21830
uniprot id: F6EPE9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

443218:AS9A RS02680
gene id: 443218:AS9A_RS02680
uniprot id: F6EIT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

443218:AS9A RS00280
gene id: 443218:AS9A_RS00280
uniprot id: F6ERJ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS07325
gene id: 443218:AS9A_RS07325
uniprot id: F6EI20
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

443218:AS9A RS03610
gene id: 443218:AS9A_RS03610
uniprot id: F6ELA2
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

443218:AS9A RS06950
gene id: 443218:AS9A_RS06950
uniprot id: F6EH53
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

443218:AS9A RS16440
gene id: 443218:AS9A_RS16440
uniprot id: F6EQJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

443218:AS9A RS08580
gene id: 443218:AS9A_RS08580
uniprot id: F6ELI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

443218:AS9A RS00730
gene id: 443218:AS9A_RS00730
uniprot id: F6EEF6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

443218:AS9A RS14075
gene id: 443218:AS9A_RS14075
uniprot id: F6EK17
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

443218:AS9A RS04105
gene id: 443218:AS9A_RS04105
uniprot id: F6EM93
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

443218:AS9A RS18950
gene id: 443218:AS9A_RS18950
uniprot id: F6EHN5
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS17680
gene id: 443218:AS9A_RS17680
uniprot id: F6EEZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

443218:AS9A RS01770
gene id: 443218:AS9A_RS01770
uniprot id: F6EGZ9
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS10755
gene id: 443218:AS9A_RS10755
uniprot id: F6EQI7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

443218:AS9A RS01800
gene id: 443218:AS9A_RS01800
uniprot id: F6EH05
names: Similarity
messages: Belongs to the ABC transporter superfamily.

443218:AS9A RS13215
gene id: 443218:AS9A_RS13215
uniprot id: F6EI87
names: Similarity
messages: Belongs to the peptidase S33 family.

443218:AS9A RS03535
gene id: 443218:AS9A_RS03535
uniprot id: F6EL86
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

443218:AS9A RS12720
gene id: 443218:AS9A_RS12720
uniprot id: F6EHB1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS00545
gene id: 443218:AS9A_RS00545
uniprot id: F6EEB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS14210
gene id: 443218:AS9A_RS14210
uniprot id: F6EKS2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS12760
gene id: 443218:AS9A_RS12760
uniprot id: F6EHB9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443218:AS9A RS07780
gene id: 443218:AS9A_RS07780
uniprot id: F6EIZ7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

443218:AS9A RS08935
gene id: 443218:AS9A_RS08935
uniprot id: F6EMD7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS14645
gene id: 443218:AS9A_RS14645
uniprot id: F6ELP1
names: Similarity
messages: Belongs to the pirin family.

443218:AS9A RS04910
gene id: 443218:AS9A_RS04910
uniprot id: F6EPN2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS07195
gene id: 443218:AS9A_RS07195
uniprot id: F6EHZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

443218:AS9A RS21195
gene id: 443218:AS9A_RS21195
uniprot id: F6EMX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

443218:AS9A RS06405
gene id: 443218:AS9A_RS06405
uniprot id: F6EFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

443218:AS9A RS09665
gene id: 443218:AS9A_RS09665
uniprot id: F6ENX8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS20990
gene id: 443218:AS9A_RS20990
uniprot id: F6EMT2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

443218:AS9A RS04650
gene id: 443218:AS9A_RS04650
uniprot id: F6EPH9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS11695
gene id: 443218:AS9A_RS11695
uniprot id: F6EES5
names: Similarity
messages: Belongs to the hyi family.

443218:AS9A RS07510
gene id: 443218:AS9A_RS07510
uniprot id: F6EIU1
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS20140
gene id: 443218:AS9A_RS20140
uniprot id: F6EKA4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

443218:AS9A RS05440
gene id: 443218:AS9A_RS05440
uniprot id: F6EQW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

443218:AS9A RS00205
gene id: 443218:AS9A_RS00205
uniprot id: F6ERI0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

443218:AS9A RS03500
gene id: 443218:AS9A_RS03500
uniprot id: F6EL78
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS11125
gene id: 443218:AS9A_RS11125
uniprot id: F6ERT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

443218:AS9A RS05075
gene id: 443218:AS9A_RS05075
uniprot id: F6EQ79
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

443218:AS9A RS02375
gene id: 443218:AS9A_RS02375
uniprot id: F6EIL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

443218:AS9A RS02890
gene id: 443218:AS9A_RS02890
uniprot id: F6EJJ8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

443218:AS9A RS16325
gene id: 443218:AS9A_RS16325
uniprot id: F6EQ27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS16230
gene id: 443218:AS9A_RS16230
uniprot id: F6EQ08
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS01015
gene id: 443218:AS9A_RS01015
uniprot id: F6EF89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

443218:AS9A RS17590
gene id: 443218:AS9A_RS17590
uniprot id: F6EEX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

443218:AS9A RS09815
gene id: 443218:AS9A_RS09815
uniprot id: F6EP09
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

443218:AS9A RS05445
gene id: 443218:AS9A_RS05445
uniprot id: F6EQW5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

443218:AS9A RS16825
gene id: 443218:AS9A_RS16825
uniprot id: F6ER77
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS24635
gene id: 443218:AS9A_RS24635
uniprot id: F6ES10
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS18935
gene id: 443218:AS9A_RS18935
uniprot id: F6EHN1
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS10205
gene id: 443218:AS9A_RS10205
uniprot id: F6EPS9
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

443218:AS9A RS00475
gene id: 443218:AS9A_RS00475
uniprot id: F6EEA5
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

443218:AS9A RS19055
gene id: 443218:AS9A_RS19055
uniprot id: F6EIC9
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

443218:AS9A RS18430
gene id: 443218:AS9A_RS18430
uniprot id: F6EGP8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

443218:AS9A RS05180
gene id: 443218:AS9A_RS05180
uniprot id: F6EQA0
names: Similarity
messages: Belongs to the peptidase M1 family.

443218:AS9A RS08110
gene id: 443218:AS9A_RS08110
uniprot id: F6EJV4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS11610
gene id: 443218:AS9A_RS11610
uniprot id: F6EEQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS18590
gene id: 443218:AS9A_RS18590
uniprot id: F6EGT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

443218:AS9A RS12600
gene id: 443218:AS9A_RS12600
uniprot id: F6EGL2
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS04505
gene id: 443218:AS9A_RS04505
uniprot id: F6EN66
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

443218:AS9A RS10425
gene id: 443218:AS9A_RS10425
uniprot id: F6EQB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

443218:AS9A RS16345
gene id: 443218:AS9A_RS16345
uniprot id: F6EQ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

443218:AS9A RS09130
gene id: 443218:AS9A_RS09130
uniprot id: F6EMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

443218:AS9A RS17705
gene id: 443218:AS9A_RS17705
uniprot id: F6EEZ6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

443218:AS9A RS06280
gene id: 443218:AS9A_RS06280
uniprot id: F6EFD4
names: Similarity
messages: Belongs to the arsA ATPase family.

443218:AS9A RS16515
gene id: 443218:AS9A_RS16515
uniprot id: F6EQL3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS03475
gene id: 443218:AS9A_RS03475
uniprot id: F6EKJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

443218:AS9A RS13195
gene id: 443218:AS9A_RS13195
uniprot id: F6EI83
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

443218:AS9A RS04520
gene id: 443218:AS9A_RS04520
uniprot id: F6EN69
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443218:AS9A RS05805
gene id: 443218:AS9A_RS05805
uniprot id: F6ERS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

443218:AS9A RS03315
gene id: 443218:AS9A_RS03315
uniprot id: F6EKG2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

443218:AS9A RS01885
gene id: 443218:AS9A_RS01885
uniprot id: F6EH23
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

443218:AS9A RS05085
gene id: 443218:AS9A_RS05085
uniprot id: F6EQ81
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS17105
gene id: 443218:AS9A_RS17105
uniprot id: F6ERD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

443218:AS9A RS09010
gene id: 443218:AS9A_RS09010
uniprot id: F6EMF2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS10430
gene id: 443218:AS9A_RS10430
uniprot id: F6EQB7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

443218:AS9A RS19165
gene id: 443218:AS9A_RS19165
uniprot id: F6EIF1
names: Similarity
messages: Belongs to the peptidase S13 family.

443218:AS9A RS03480
gene id: 443218:AS9A_RS03480
uniprot id: F6EL74
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS04820
gene id: 443218:AS9A_RS04820
uniprot id: F6EPL4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

443218:AS9A RS15095
gene id: 443218:AS9A_RS15095
uniprot id: F6EMM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

443218:AS9A RS06585
gene id: 443218:AS9A_RS06585
uniprot id: F6EG89
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

443218:AS9A RS06915
gene id: 443218:AS9A_RS06915
uniprot id: F6EH45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

443218:AS9A RS06605
gene id: 443218:AS9A_RS06605
uniprot id: F6EG93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

443218:AS9A RS21155
gene id: 443218:AS9A_RS21155
uniprot id: F6EMW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

443218:AS9A RS07430
gene id: 443218:AS9A_RS07430
uniprot id: F6EI39
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

443218:AS9A RS23505
gene id: 443218:AS9A_RS23505
uniprot id: F6EPG8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

443218:AS9A RS18460
gene id: 443218:AS9A_RS18460
uniprot id: F6EGQ4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

443218:AS9A RS01730
gene id: 443218:AS9A_RS01730
uniprot id: F6EGZ1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

443218:AS9A RS15110
gene id: 443218:AS9A_RS15110
uniprot id: F6EMN0
names: Similarity
messages: Belongs to the UPF0749 family.

443218:AS9A RS12595
gene id: 443218:AS9A_RS12595
uniprot id: F6EGL1
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

443218:AS9A RS06380
gene id: 443218:AS9A_RS06380
uniprot id: F6EFF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

443218:AS9A RS00350
gene id: 443218:AS9A_RS00350
uniprot id: F6ERL1
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS06920
gene id: 443218:AS9A_RS06920
uniprot id: F6EH46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

443218:AS9A RS09450
gene id: 443218:AS9A_RS09450
uniprot id: F6ENC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

443218:AS9A RS09555
gene id: 443218:AS9A_RS09555
uniprot id: F6ENF0
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

443218:AS9A RS04780
gene id: 443218:AS9A_RS04780
uniprot id: F6EPK6
names: Similarity
messages: Belongs to the peptidase S33 family.

443218:AS9A RS19380
gene id: 443218:AS9A_RS19380
uniprot id: F6EIJ5
names: Similarity
messages: Belongs to the WXG100 family.

443218:AS9A RS11605
gene id: 443218:AS9A_RS11605
uniprot id: F6EEQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS06640
gene id: 443218:AS9A_RS06640
uniprot id: F6EGA1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

443218:AS9A RS05270
gene id: 443218:AS9A_RS05270
uniprot id: F6EQS8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

443218:AS9A RS15120
gene id: 443218:AS9A_RS15120
uniprot id: F6EMN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

443218:AS9A RS15490
gene id: 443218:AS9A_RS15490
uniprot id: F6ENJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

443218:AS9A RS21185
gene id: 443218:AS9A_RS21185
uniprot id: F6EMX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

443218:AS9A RS08575
gene id: 443218:AS9A_RS08575
uniprot id: F6ELH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS16305
gene id: 443218:AS9A_RS16305
uniprot id: F6EQ23
names: Similarity
messages: Belongs to the FBPase class 2 family.

443218:AS9A RS01765
gene id: 443218:AS9A_RS01765
uniprot id: F6EGZ8
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS18765
gene id: 443218:AS9A_RS18765
uniprot id: F6EHJ2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

443218:AS9A RS15665
gene id: 443218:AS9A_RS15665
uniprot id: F6ENN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

443218:AS9A RS02410
gene id: 443218:AS9A_RS02410
uniprot id: F6EIM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

443218:AS9A RS08085
gene id: 443218:AS9A_RS08085
uniprot id: F6EJU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

443218:AS9A RS00650
gene id: 443218:AS9A_RS00650
uniprot id: F6EEE0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

443218:AS9A RS16210
gene id: 443218:AS9A_RS16210
uniprot id: F6EQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

443218:AS9A RS00140
gene id: 443218:AS9A_RS00140
uniprot id: F6ERG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

443218:AS9A RS08950
gene id: 443218:AS9A_RS08950
uniprot id: F6EME0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

443218:AS9A RS04940
gene id: 443218:AS9A_RS04940
uniprot id: F6EQ49
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

443218:AS9A RS15980
gene id: 443218:AS9A_RS15980
uniprot id: F6EPB1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS18500
gene id: 443218:AS9A_RS18500
uniprot id: F6EGR2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

443218:AS9A RS01905
gene id: 443218:AS9A_RS01905
uniprot id: F6EH27
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

443218:AS9A RS03960
gene id: 443218:AS9A_RS03960
uniprot id: F6EM61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS15285
gene id: 443218:AS9A_RS15285
uniprot id: F6EMR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

443218:AS9A RS19310
gene id: 443218:AS9A_RS19310
uniprot id: F6EII2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

443218:AS9A RS02365
gene id: 443218:AS9A_RS02365
uniprot id: F6EIL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

443218:AS9A RS18315
gene id: 443218:AS9A_RS18315
uniprot id: F6EGM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS12530
gene id: 443218:AS9A_RS12530
uniprot id: F6EGJ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

443218:AS9A RS02810
gene id: 443218:AS9A_RS02810
uniprot id: F6EJI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

443218:AS9A RS14260
gene id: 443218:AS9A_RS14260
uniprot id: F6EKT2
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

443218:AS9A RS06660
gene id: 443218:AS9A_RS06660
uniprot id: F6EGA5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

443218:AS9A RS11765
gene id: 443218:AS9A_RS11765
uniprot id: F6EEU0
names: Similarity
messages: Belongs to the YciI family.

443218:AS9A RS12470
gene id: 443218:AS9A_RS12470
uniprot id: F6EGI4
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS14460
gene id: 443218:AS9A_RS14460
uniprot id: F6EKX2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

443218:AS9A RS01855
gene id: 443218:AS9A_RS01855
uniprot id: F6EH17
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

443218:AS9A RS03420
gene id: 443218:AS9A_RS03420
uniprot id: F6EKI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

443218:AS9A RS01860
gene id: 443218:AS9A_RS01860
uniprot id: F6EH18
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

443218:AS9A RS18990
gene id: 443218:AS9A_RS18990
uniprot id: F6EHP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

443218:AS9A RS09445
gene id: 443218:AS9A_RS09445
uniprot id: F6ENC8
names: Similarity
messages: Belongs to the UPF0098 family.

443218:AS9A RS07925
gene id: 443218:AS9A_RS07925
uniprot id: F6EJR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

443218:AS9A RS14300
gene id: 443218:AS9A_RS14300
uniprot id: F6EKU0
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS06710
gene id: 443218:AS9A_RS06710
uniprot id: F6EGB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS15290
gene id: 443218:AS9A_RS15290
uniprot id: F6EMR7
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

443218:AS9A RS03200
gene id: 443218:AS9A_RS03200
uniprot id: F6EKE0
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

443218:AS9A RS01200
gene id: 443218:AS9A_RS01200
uniprot id: F6EG04
names: Similarity
messages: Belongs to the catalase family.

443218:AS9A RS08945
gene id: 443218:AS9A_RS08945
uniprot id: F6EMD9
names: Similarity
messages: Belongs to the peptidase M24B family.

443218:AS9A RS18380
gene id: 443218:AS9A_RS18380
uniprot id: F6EGN7
names: Similarity
messages: Belongs to the SufE family.

443218:AS9A RS18225
gene id: 443218:AS9A_RS18225
uniprot id: F6EFX6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

443218:AS9A RS14620
gene id: 443218:AS9A_RS14620
uniprot id: F6ELN6
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS10640
gene id: 443218:AS9A_RS10640
uniprot id: F6EQG4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

443218:AS9A RS00310
gene id: 443218:AS9A_RS00310
uniprot id: F6ERK2
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS12200
gene id: 443218:AS9A_RS12200
uniprot id: F6EFP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

443218:AS9A RS04935
gene id: 443218:AS9A_RS04935
uniprot id: F6EQ48
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS02745
gene id: 443218:AS9A_RS02745
uniprot id: F6EJH0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

443218:AS9A RS09795
gene id: 443218:AS9A_RS09795
uniprot id: F6EP05
names: Similarity
messages: Belongs to the peptidase M24B family.

443218:AS9A RS20110
gene id: 443218:AS9A_RS20110
uniprot id: F6EK98
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS12105
gene id: 443218:AS9A_RS12105
uniprot id: F6EFN0
names: Similarity
messages: Belongs to the RutC family.

443218:AS9A RS17760
gene id: 443218:AS9A_RS17760
uniprot id: F6EF07
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

443218:AS9A RS19515
gene id: 443218:AS9A_RS19515
uniprot id: F6EJ98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

443218:AS9A RS05315
gene id: 443218:AS9A_RS05315
uniprot id: F6EQT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS02300
gene id: 443218:AS9A_RS02300
uniprot id: F6EHY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

443218:AS9A RS04915
gene id: 443218:AS9A_RS04915
uniprot id: F6EPN3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS06480
gene id: 443218:AS9A_RS06480
uniprot id: F6EFH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS12070
gene id: 443218:AS9A_RS12070
uniprot id: F6EFM3
names: Similarity
messages: Belongs to the TPP enzyme family.

443218:AS9A RS19345
gene id: 443218:AS9A_RS19345
uniprot id: F6EII9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

443218:AS9A RS21180
gene id: 443218:AS9A_RS21180
uniprot id: F6EMX2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

443218:AS9A RS05405
gene id: 443218:AS9A_RS05405
uniprot id: F6EQV6
names: Similarity
messages: Belongs to the protein kinase superfamily.

443218:AS9A RS15570
gene id: 443218:AS9A_RS15570
uniprot id: F6ENL3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

443218:AS9A RS12150
gene id: 443218:AS9A_RS12150
uniprot id: F6EFN9
names: Similarity
messages: Belongs to the YciI family.

443218:AS9A RS06995
gene id: 443218:AS9A_RS06995
uniprot id: F6EH62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

443218:AS9A RS03170
gene id: 443218:AS9A_RS03170
uniprot id: F6EKD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

443218:AS9A RS01535
gene id: 443218:AS9A_RS01535
uniprot id: F6EG70
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

443218:AS9A RS15425
gene id: 443218:AS9A_RS15425
uniprot id: F6ENI2
names: Subcellular Location Annotation
messages: Cytoplasm

443218:AS9A RS06245
gene id: 443218:AS9A_RS06245
uniprot id: F6EFC7
names: Similarity
messages: Belongs to the peptidase C40 family.

443218:AS9A RS02310
gene id: 443218:AS9A_RS02310
uniprot id: F6EIK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

443218:AS9A RS10175
gene id: 443218:AS9A_RS10175
uniprot id: F6EPS2
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS12690
gene id: 443218:AS9A_RS12690
uniprot id: F6EHA5
names: Subcellular Location Annotation
messages: Cytoplasm

443218:AS9A RS16990
gene id: 443218:AS9A_RS16990
uniprot id: F6ERB2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS17670
gene id: 443218:AS9A_RS17670
uniprot id: F6EEY9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS16685
gene id: 443218:AS9A_RS16685
uniprot id: F6EQQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

443218:AS9A RS19875
gene id: 443218:AS9A_RS19875
uniprot id: F6EK49
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

443218:AS9A RS00480
gene id: 443218:AS9A_RS00480
uniprot id: F6EEA6
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

443218:AS9A RS21200
gene id: 443218:AS9A_RS21200
uniprot id: F6EMX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

443218:AS9A RS01030
gene id: 443218:AS9A_RS01030
uniprot id: F6EF92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

443218:AS9A RS07520
gene id: 443218:AS9A_RS07520
uniprot id: F6EIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS01850
gene id: 443218:AS9A_RS01850
uniprot id: F6EH15
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS16950
gene id: 443218:AS9A_RS16950
uniprot id: F6ERA3
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS15540
gene id: 443218:AS9A_RS15540
uniprot id: F6ENK7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

443218:AS9A RS17380
gene id: 443218:AS9A_RS17380
uniprot id: F6ES63
names: Similarity
messages: Belongs to the peptidase S58 family.

443218:AS9A RS12175
gene id: 443218:AS9A_RS12175
uniprot id: F6EFP4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

443218:AS9A RS16390
gene id: 443218:AS9A_RS16390
uniprot id: F6EQ42
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

443218:AS9A RS09320
gene id: 443218:AS9A_RS09320
uniprot id: F6ENA4
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS12380
gene id: 443218:AS9A_RS12380
uniprot id: F6EGG1
names: Similarity
messages: Belongs to the neutral ceramidase family.

443218:AS9A RS12840
gene id: 443218:AS9A_RS12840
uniprot id: F6EHD8
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS03515
gene id: 443218:AS9A_RS03515
uniprot id: F6EL82
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.
messages: Belongs to the FMO family.

443218:AS9A RS20780
gene id: 443218:AS9A_RS20780
uniprot id: F6ELZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS00995
gene id: 443218:AS9A_RS00995
uniprot id: F6EF85
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS09945
gene id: 443218:AS9A_RS09945
uniprot id: F6EP37
names: Similarity
messages: Belongs to the peptidase U62 family.

443218:AS9A RS04545
gene id: 443218:AS9A_RS04545
uniprot id: F6EN74
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS17875
gene id: 443218:AS9A_RS17875
uniprot id: F6EF31
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS04375
gene id: 443218:AS9A_RS04375
uniprot id: F6EN38
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS06705
gene id: 443218:AS9A_RS06705
uniprot id: F6EGB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS16430
gene id: 443218:AS9A_RS16430
uniprot id: F6EQJ5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

443218:AS9A RS00925
gene id: 443218:AS9A_RS00925
uniprot id: F6EF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS16295
gene id: 443218:AS9A_RS16295
uniprot id: F6EQ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

443218:AS9A RS14290
gene id: 443218:AS9A_RS14290
uniprot id: F6EKT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

443218:AS9A RS16920
gene id: 443218:AS9A_RS16920
uniprot id: F6ER97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS14205
gene id: 443218:AS9A_RS14205
uniprot id: F6EKS1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS21100
gene id: 443218:AS9A_RS21100
uniprot id: F6EMV5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

443218:AS9A RS08750
gene id: 443218:AS9A_RS08750
uniprot id: F6ELL0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

443218:AS9A RS07270
gene id: 443218:AS9A_RS07270
uniprot id: F6EI09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

443218:AS9A RS14375
gene id: 443218:AS9A_RS14375
uniprot id: F6EKV5
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS04205
gene id: 443218:AS9A_RS04205
uniprot id: F6EMB5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

443218:AS9A RS06385
gene id: 443218:AS9A_RS06385
uniprot id: F6EFF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

443218:AS9A RS20815
gene id: 443218:AS9A_RS20815
uniprot id: F6EM06
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

443218:AS9A RS17665
gene id: 443218:AS9A_RS17665
uniprot id: F6EEY8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

443218:AS9A RS10705
gene id: 443218:AS9A_RS10705
uniprot id: F6EQH8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS21015
gene id: 443218:AS9A_RS21015
uniprot id: F6EMT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS17905
gene id: 443218:AS9A_RS17905
uniprot id: F6EF38
names: Similarity
messages: Belongs to the peptidase S16 family.

443218:AS9A RS21735
gene id: 443218:AS9A_RS21735
uniprot id: F6EPD0
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

443218:AS9A RS00215
gene id: 443218:AS9A_RS00215
uniprot id: F6ERI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

443218:AS9A RS06160
gene id: 443218:AS9A_RS06160
uniprot id: F6EEM4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

443218:AS9A RS01120
gene id: 443218:AS9A_RS01120
uniprot id: F6EFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS17475
gene id: 443218:AS9A_RS17475
uniprot id: F6ES82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

443218:AS9A RS09820
gene id: 443218:AS9A_RS09820
uniprot id: F6EP10
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

443218:AS9A RS18580
gene id: 443218:AS9A_RS18580
uniprot id: F6EGS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

443218:AS9A RS15060
gene id: 443218:AS9A_RS15060
uniprot id: F6EMM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

443218:AS9A RS03350
gene id: 443218:AS9A_RS03350
uniprot id: F6EKG9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

443218:AS9A RS10025
gene id: 443218:AS9A_RS10025
uniprot id: F6EPP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

443218:AS9A RS18630
gene id: 443218:AS9A_RS18630
uniprot id: F6EGU0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

443218:AS9A RS17060
gene id: 443218:AS9A_RS17060
uniprot id: F6ERC6
names: Similarity
messages: Belongs to the peptidase S1C family.

443218:AS9A RS02325
gene id: 443218:AS9A_RS02325
uniprot id: F6EIK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

443218:AS9A RS08370
gene id: 443218:AS9A_RS08370
uniprot id: F6EKP8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS09145
gene id: 443218:AS9A_RS09145
uniprot id: F6EMI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

443218:AS9A RS21650
gene id: 443218:AS9A_RS21650
uniprot id: F6ENV5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS17020
gene id: 443218:AS9A_RS17020
uniprot id: F6ERB7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

443218:AS9A RS06925
gene id: 443218:AS9A_RS06925
uniprot id: F6EH47
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

443218:AS9A RS09470
gene id: 443218:AS9A_RS09470
uniprot id: F6END3
names: Similarity
messages: Belongs to the neocarzinostatin family.

443218:AS9A RS21425
gene id: 443218:AS9A_RS21425
uniprot id: F6ENQ8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

443218:AS9A RS06840
gene id: 443218:AS9A_RS06840
uniprot id: F6EH30
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

443218:AS9A RS16845
gene id: 443218:AS9A_RS16845
uniprot id: F6ER82
names: Similarity
messages: Belongs to the FPG family.

443218:AS9A RS14610
gene id: 443218:AS9A_RS14610
uniprot id: F6ELN4
names: Similarity
messages: Belongs to the PrpD family.

443218:AS9A RS19880
gene id: 443218:AS9A_RS19880
uniprot id: F6EK50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS14250
gene id: 443218:AS9A_RS14250
uniprot id: F6EKT0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

443218:AS9A RS16470
gene id: 443218:AS9A_RS16470
uniprot id: F6EQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS13815
gene id: 443218:AS9A_RS13815
uniprot id: F6EJV9
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS16015
gene id: 443218:AS9A_RS16015
uniprot id: F6EPC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

443218:AS9A RS03005
gene id: 443218:AS9A_RS03005
uniprot id: F6EJM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

443218:AS9A RS03175
gene id: 443218:AS9A_RS03175
uniprot id: F6EKD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS16525
gene id: 443218:AS9A_RS16525
uniprot id: F6EQL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

443218:AS9A RS20890
gene id: 443218:AS9A_RS20890
uniprot id: F6EM21
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

443218:AS9A RS08510
gene id: 443218:AS9A_RS08510
uniprot id: F6ELG5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

443218:AS9A RS05950
gene id: 443218:AS9A_RS05950
uniprot id: F6EEI1
names: Similarity
messages: Belongs to the CdaR family.

443218:AS9A RS10195
gene id: 443218:AS9A_RS10195
uniprot id: F6EPS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

443218:AS9A RS06440
gene id: 443218:AS9A_RS06440
uniprot id: F6EFG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

443218:AS9A RS17285
gene id: 443218:AS9A_RS17285
uniprot id: F6ES45
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

443218:AS9A RS09970
gene id: 443218:AS9A_RS09970
uniprot id: F6EP42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

443218:AS9A RS07575
gene id: 443218:AS9A_RS07575
uniprot id: F6EIV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

443218:AS9A RS06000
gene id: 443218:AS9A_RS06000
uniprot id: F6EEJ1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

443218:AS9A RS18790
gene id: 443218:AS9A_RS18790
uniprot id: F6EHJ9
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

443218:AS9A RS19335
gene id: 443218:AS9A_RS19335
uniprot id: F6EII7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

443218:AS9A RS06145
gene id: 443218:AS9A_RS06145
uniprot id: F6EEM1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

443218:AS9A RS04685
gene id: 443218:AS9A_RS04685
uniprot id: F6EPI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

443218:AS9A RS08725
gene id: 443218:AS9A_RS08725
uniprot id: F6ELK5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

443218:AS9A RS04140
gene id: 443218:AS9A_RS04140
uniprot id: F6EMA0
names: Similarity
messages: Belongs to the citrate synthase family.

443218:AS9A RS19410
gene id: 443218:AS9A_RS19410
uniprot id: F6EIK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

443218:AS9A RS06645
gene id: 443218:AS9A_RS06645
uniprot id: F6EGA2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

443218:AS9A RS00610
gene id: 443218:AS9A_RS00610
uniprot id: F6EED2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

443218:AS9A RS05360
gene id: 443218:AS9A_RS05360
uniprot id: F6EQU7
names: Similarity
messages: Belongs to the pirin family.

443218:AS9A RS21435
gene id: 443218:AS9A_RS21435
uniprot id: F6ENR0
names: Subcellular Location Annotation
messages: Cytoplasm

443218:AS9A RS09110
gene id: 443218:AS9A_RS09110
uniprot id: F6EMH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

443218:AS9A RS21915
gene id: 443218:AS9A_RS21915
uniprot id: F6EPG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

443218:AS9A RS20170
gene id: 443218:AS9A_RS20170
uniprot id: F6EKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

443218:AS9A RS04480
gene id: 443218:AS9A_RS04480
uniprot id: F6EN61
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

443218:AS9A RS03855
gene id: 443218:AS9A_RS03855
uniprot id: F6EM37
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS07690
gene id: 443218:AS9A_RS07690
uniprot id: F6EIX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

443218:AS9A RS21465
gene id: 443218:AS9A_RS21465
uniprot id: F6ENR6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

443218:AS9A RS07365
gene id: 443218:AS9A_RS07365
uniprot id: F6EI25
names: Similarity
messages: Belongs to the TlyA family.

443218:AS9A RS09765
gene id: 443218:AS9A_RS09765
uniprot id: F6ENZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

443218:AS9A RS16565
gene id: 443218:AS9A_RS16565
uniprot id: F6EQM4
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

443218:AS9A RS12555
gene id: 443218:AS9A_RS12555
uniprot id: F6EGK2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS20635
gene id: 443218:AS9A_RS20635
uniprot id: F6ELW8
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS09140
gene id: 443218:AS9A_RS09140
uniprot id: F6EMH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

443218:AS9A RS18550
gene id: 443218:AS9A_RS18550
uniprot id: F6EGS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS17795
gene id: 443218:AS9A_RS17795
uniprot id: F6EF14
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS21270
gene id: 443218:AS9A_RS21270
uniprot id: F6EMZ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS03680
gene id: 443218:AS9A_RS03680
uniprot id: F6ELB6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

443218:AS9A RS17805
gene id: 443218:AS9A_RS17805
uniprot id: F6EF16
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

443218:AS9A RS11415
gene id: 443218:AS9A_RS11415
uniprot id: F6ERZ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS00605
gene id: 443218:AS9A_RS00605
uniprot id: F6EED1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

443218:AS9A RS17080
gene id: 443218:AS9A_RS17080
uniprot id: F6ERD0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

443218:AS9A RS06620
gene id: 443218:AS9A_RS06620
uniprot id: F6EG97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

443218:AS9A RS15715
gene id: 443218:AS9A_RS15715
uniprot id: F6EP51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

443218:AS9A RS18365
gene id: 443218:AS9A_RS18365
uniprot id: F6EGN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

443218:AS9A RS18490
gene id: 443218:AS9A_RS18490
uniprot id: F6EGR0
names: Similarity
messages: Belongs to the universal stress protein A family.

443218:AS9A RS02665
gene id: 443218:AS9A_RS02665
uniprot id: F6EIS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

443218:AS9A RS16505
gene id: 443218:AS9A_RS16505
uniprot id: F6EQL1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443218:AS9A RS02330
gene id: 443218:AS9A_RS02330
uniprot id: F6EIL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

443218:AS9A RS07035
gene id: 443218:AS9A_RS07035
uniprot id: F6EH70
names: Similarity
messages: Belongs to the TrpC family.

443218:AS9A RS08860
gene id: 443218:AS9A_RS08860
uniprot id: F6EMC2
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS20850
gene id: 443218:AS9A_RS20850
uniprot id: F6EM13
names: Similarity
messages: Belongs to the AccD/PCCB family.

443218:AS9A RS07390
gene id: 443218:AS9A_RS07390
uniprot id: F6EI31
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS08500
gene id: 443218:AS9A_RS08500
uniprot id: F6ELG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

443218:AS9A RS03990
gene id: 443218:AS9A_RS03990
uniprot id: F6EM67
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

443218:AS9A RS09005
gene id: 443218:AS9A_RS09005
uniprot id: F6EMF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

443218:AS9A RS19860
gene id: 443218:AS9A_RS19860
uniprot id: F6EK45
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

443218:AS9A RS05290
gene id: 443218:AS9A_RS05290
uniprot id: F6EQT1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

443218:AS9A RS00195
gene id: 443218:AS9A_RS00195
uniprot id: F6ERH8
names: Similarity
messages: Belongs to the glutamate synthase family.

443218:AS9A RS19295
gene id: 443218:AS9A_RS19295
uniprot id: F6EIH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

443218:AS9A RS03130
gene id: 443218:AS9A_RS03130
uniprot id: F6EKC6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

443218:AS9A RS13190
gene id: 443218:AS9A_RS13190
uniprot id: F6EI82
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS08550
gene id: 443218:AS9A_RS08550
uniprot id: F6ELH3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

443218:AS9A RS19650
gene id: 443218:AS9A_RS19650
uniprot id: F6EJC6
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS12260
gene id: 443218:AS9A_RS12260
uniprot id: F6EFR1
names: Similarity
messages: Belongs to the universal stress protein A family.

443218:AS9A RS06455
gene id: 443218:AS9A_RS06455
uniprot id: F6EFH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

443218:AS9A RS03275
gene id: 443218:AS9A_RS03275
uniprot id: F6EKF4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

443218:AS9A RS06690
gene id: 443218:AS9A_RS06690
uniprot id: F6EGB1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

443218:AS9A RS16245
gene id: 443218:AS9A_RS16245
uniprot id: F6EQ11
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

443218:AS9A RS19095
gene id: 443218:AS9A_RS19095
uniprot id: F6EID7
names: Similarity
messages: Belongs to the thioesterase family.

443218:AS9A RS16435
gene id: 443218:AS9A_RS16435
uniprot id: F6EQJ6
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

443218:AS9A RS02155
gene id: 443218:AS9A_RS02155
uniprot id: F6EHU8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS08955
gene id: 443218:AS9A_RS08955
uniprot id: F6EME1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

443218:AS9A RS03725
gene id: 443218:AS9A_RS03725
uniprot id: F6ELC3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS05520
gene id: 443218:AS9A_RS05520
uniprot id: F6EQY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

443218:AS9A RS10655
gene id: 443218:AS9A_RS10655
uniprot id: F6EQG7
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS21025
gene id: 443218:AS9A_RS21025
uniprot id: F6EMT9
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

443218:AS9A RS21905
gene id: 443218:AS9A_RS21905
uniprot id: F6EPG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

443218:AS9A RS18015
gene id: 443218:AS9A_RS18015
uniprot id: F6EFT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

443218:AS9A RS21160
gene id: 443218:AS9A_RS21160
uniprot id: F6EMW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

443218:AS9A RS06780
gene id: 443218:AS9A_RS06780
uniprot id: F6EGD0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

443218:AS9A RS10265
gene id: 443218:AS9A_RS10265
uniprot id: F6EPU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

443218:AS9A RS02730
gene id: 443218:AS9A_RS02730
uniprot id: F6EJG7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

443218:AS9A RS03595
gene id: 443218:AS9A_RS03595
uniprot id: F6EL99
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS03580
gene id: 443218:AS9A_RS03580
uniprot id: F6EL96
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS02495
gene id: 443218:AS9A_RS02495
uniprot id: F6EIP2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

443218:AS9A RS21175
gene id: 443218:AS9A_RS21175
uniprot id: F6EMX1
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

443218:AS9A RS16200
gene id: 443218:AS9A_RS16200
uniprot id: F6EQ00
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

443218:AS9A RS08965
gene id: 443218:AS9A_RS08965
uniprot id: F6EME3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

443218:AS9A RS05450
gene id: 443218:AS9A_RS05450
uniprot id: F6EQW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

443218:AS9A RS00845
gene id: 443218:AS9A_RS00845
uniprot id: F6EF53
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

443218:AS9A RS19795
gene id: 443218:AS9A_RS19795
uniprot id: F6EJF7
names: Similarity
messages: Belongs to the UPF0166 family.

443218:AS9A RS18205
gene id: 443218:AS9A_RS18205
uniprot id: F6EFX2
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

443218:AS9A RS01970
gene id: 443218:AS9A_RS01970
uniprot id: F6EHR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

443218:AS9A RS14135
gene id: 443218:AS9A_RS14135
uniprot id: F6EK29
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

443218:AS9A RS20010
gene id: 443218:AS9A_RS20010
uniprot id: F6EK75
names: Similarity
messages: Belongs to the allantoicase family.

443218:AS9A RS11895
gene id: 443218:AS9A_RS11895
uniprot id: F6EFI8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS19495
gene id: 443218:AS9A_RS19495
uniprot id: F6EJ94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

443218:AS9A RS06415
gene id: 443218:AS9A_RS06415
uniprot id: F6EFG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

443218:AS9A RS18620
gene id: 443218:AS9A_RS18620
uniprot id: F6EGT8
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

443218:AS9A RS12640
gene id: 443218:AS9A_RS12640
uniprot id: F6EH95
names: Similarity
messages: Belongs to the AHA1 family.

443218:AS9A RS10170
gene id: 443218:AS9A_RS10170
uniprot id: F6EPS1
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS20065
gene id: 443218:AS9A_RS20065
uniprot id: F6EK88
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS22395
gene id: 443218:AS9A_RS22395
uniprot id: F6ESM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

443218:AS9A RS02170
gene id: 443218:AS9A_RS02170
uniprot id: F6EHV1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS10145
gene id: 443218:AS9A_RS10145
uniprot id: F6EPR5
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS07835
gene id: 443218:AS9A_RS07835
uniprot id: F6EJP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

443218:AS9A RS10925
gene id: 443218:AS9A_RS10925
uniprot id: F6ER22
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS19375
gene id: 443218:AS9A_RS19375
uniprot id: F6EIJ4
names: Similarity
messages: Belongs to the WXG100 family.

443218:AS9A RS11430
gene id: 443218:AS9A_RS11430
uniprot id: F6ES02
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

443218:AS9A RS06885
gene id: 443218:AS9A_RS06885
uniprot id: F6EH39
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

443218:AS9A RS00420
gene id: 443218:AS9A_RS00420
uniprot id: F6EE94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

443218:AS9A RS16415
gene id: 443218:AS9A_RS16415
uniprot id: F6EQJ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS19945
gene id: 443218:AS9A_RS19945
uniprot id: F6EK63
names: Similarity
messages: Belongs to the peptidase M13 family.

443218:AS9A RS21375
gene id: 443218:AS9A_RS21375
uniprot id: F6ENP8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS01155
gene id: 443218:AS9A_RS01155
uniprot id: F6EFB6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS05155
gene id: 443218:AS9A_RS05155
uniprot id: F6EQ94
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

443218:AS9A RS24805
gene id: 443218:AS9A_RS24805
uniprot id: F6EQR4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

443218:AS9A RS01425
gene id: 443218:AS9A_RS01425
uniprot id: F6EG48
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

443218:AS9A RS18180
gene id: 443218:AS9A_RS18180
uniprot id: F6EFW7
names: Similarity
messages: Belongs to the thymidylate kinase family.

443218:AS9A RS15205
gene id: 443218:AS9A_RS15205
uniprot id: F6EMQ0
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

443218:AS9A RS21170
gene id: 443218:AS9A_RS21170
uniprot id: F6EMX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

443218:AS9A RS05825
gene id: 443218:AS9A_RS05825
uniprot id: F6ERS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

443218:AS9A RS06190
gene id: 443218:AS9A_RS06190
uniprot id: F6EEN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

443218:AS9A RS15645
gene id: 443218:AS9A_RS15645
uniprot id: F6ENM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

443218:AS9A RS01205
gene id: 443218:AS9A_RS01205
uniprot id: F6EG05
names: Similarity
messages: Belongs to the Dps family.

443218:AS9A RS20960
gene id: 443218:AS9A_RS20960
uniprot id: F6EMS6
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS11265
gene id: 443218:AS9A_RS11265
uniprot id: F6ERW8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

443218:AS9A RS01415
gene id: 443218:AS9A_RS01415
uniprot id: F6EG46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

443218:AS9A RS20335
gene id: 443218:AS9A_RS20335
uniprot id: F6EL21
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS08895
gene id: 443218:AS9A_RS08895
uniprot id: F6EMC9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

443218:AS9A RS02830
gene id: 443218:AS9A_RS02830
uniprot id: F6EJI8
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

443218:AS9A RS10345
gene id: 443218:AS9A_RS10345
uniprot id: F6EPV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

443218:AS9A RS20295
gene id: 443218:AS9A_RS20295
uniprot id: F6EL13
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS06420
gene id: 443218:AS9A_RS06420
uniprot id: F6EFG5
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS05890
gene id: 443218:AS9A_RS05890
uniprot id: F6EEH1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

443218:AS9A RS10530
gene id: 443218:AS9A_RS10530
uniprot id: F6EQD7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

443218:AS9A RS16745
gene id: 443218:AS9A_RS16745
uniprot id: F6EQR2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

443218:AS9A RS14565
gene id: 443218:AS9A_RS14565
uniprot id: F6EKZ3
names: Similarity
messages: Belongs to the WrbA family.

443218:AS9A RS06500
gene id: 443218:AS9A_RS06500
uniprot id: F6EFI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

443218:AS9A RS21165
gene id: 443218:AS9A_RS21165
uniprot id: F6EMW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

443218:AS9A RS24335
gene id: 443218:AS9A_RS24335
uniprot id: F6ELM3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

443218:AS9A RS10375
gene id: 443218:AS9A_RS10375
uniprot id: F6EPW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS15320
gene id: 443218:AS9A_RS15320
uniprot id: F6EMS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

443218:AS9A RS20280
gene id: 443218:AS9A_RS20280
uniprot id: F6EL10
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

443218:AS9A RS03685
gene id: 443218:AS9A_RS03685
uniprot id: F6ELB7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

443218:AS9A RS02445
gene id: 443218:AS9A_RS02445
uniprot id: F6EIN2
names: Similarity
messages: Belongs to the EccE family.

443218:AS9A RS15565
gene id: 443218:AS9A_RS15565
uniprot id: F6ENL2
names: Similarity
messages: Belongs to the UPF0045 family.

443218:AS9A RS13205
gene id: 443218:AS9A_RS13205
uniprot id: F6EI85
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS05040
gene id: 443218:AS9A_RS05040
uniprot id: F6EQ72
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

443218:AS9A RS06555
gene id: 443218:AS9A_RS06555
uniprot id: F6EG82
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS05195
gene id: 443218:AS9A_RS05195
uniprot id: F6EQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

443218:AS9A RS13110
gene id: 443218:AS9A_RS13110
uniprot id: F6EI66
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS15470
gene id: 443218:AS9A_RS15470
uniprot id: F6ENJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS13520
gene id: 443218:AS9A_RS13520
uniprot id: F6EJ27
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

443218:AS9A RS00145
gene id: 443218:AS9A_RS00145
uniprot id: F6ERG9
names: Similarity
messages: Belongs to the UPF0749 family.

443218:AS9A RS16400
gene id: 443218:AS9A_RS16400
uniprot id: F6EQ45
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

443218:AS9A RS04710
gene id: 443218:AS9A_RS04710
uniprot id: F6EPJ2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

443218:AS9A RS05870
gene id: 443218:AS9A_RS05870
uniprot id: F6ERT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

443218:AS9A RS04300
gene id: 443218:AS9A_RS04300
uniprot id: F6EN23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

443218:AS9A RS13160
gene id: 443218:AS9A_RS13160
uniprot id: F6EI76
names: Similarity
messages: Belongs to the AHA1 family.

443218:AS9A RS13440
gene id: 443218:AS9A_RS13440
uniprot id: F6EJ11
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

443218:AS9A RS20475
gene id: 443218:AS9A_RS20475
uniprot id: F6ESC4
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

443218:AS9A RS02660
gene id: 443218:AS9A_RS02660
uniprot id: F6EIS7
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

443218:AS9A RS14125
gene id: 443218:AS9A_RS14125
uniprot id: F6EK27
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

443218:AS9A RS09730
gene id: 443218:AS9A_RS09730
uniprot id: F6ENZ1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

443218:AS9A RS16140
gene id: 443218:AS9A_RS16140
uniprot id: F6EPY5
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

443218:AS9A RS08900
gene id: 443218:AS9A_RS08900
uniprot id: F6EMD0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

443218:AS9A RS17235
gene id: 443218:AS9A_RS17235
uniprot id: F6ES35
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS13285
gene id: 443218:AS9A_RS13285
uniprot id: F6EIA4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

443218:AS9A RS08760
gene id: 443218:AS9A_RS08760
uniprot id: F6ELL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

443218:AS9A RS15190
gene id: 443218:AS9A_RS15190
uniprot id: F6EMP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

443218:AS9A RS19175
gene id: 443218:AS9A_RS19175
uniprot id: F6EIF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

443218:AS9A RS17260
gene id: 443218:AS9A_RS17260
uniprot id: F6ES40
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

443218:AS9A RS01580
gene id: 443218:AS9A_RS01580
uniprot id: F6EGV7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

443218:AS9A RS17860
gene id: 443218:AS9A_RS17860
uniprot id: F6EF28
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

443218:AS9A RS02435
gene id: 443218:AS9A_RS02435
uniprot id: F6EIN1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

443218:AS9A RS02250
gene id: 443218:AS9A_RS02250
uniprot id: F6EHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS15200
gene id: 443218:AS9A_RS15200
uniprot id: F6EMP9
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

443218:AS9A RS20545
gene id: 443218:AS9A_RS20545
uniprot id: F6EL67
names: Similarity
messages: Belongs to the cytochrome P450 family.

443218:AS9A RS06460
gene id: 443218:AS9A_RS06460
uniprot id: F6EFH3
names: Similarity
messages: Belongs to the YggT family.

443218:AS9A RS16805
gene id: 443218:AS9A_RS16805
uniprot id: F6ER73
names: Similarity
messages: Belongs to the ArsC family.

443218:AS9A RS11685
gene id: 443218:AS9A_RS11685
uniprot id: F6EES3
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS10055
gene id: 443218:AS9A_RS10055
uniprot id: F6EPP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

443218:AS9A RS05415
gene id: 443218:AS9A_RS05415
uniprot id: F6EQV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

443218:AS9A RS19755
gene id: 443218:AS9A_RS19755
uniprot id: F6EJE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

443218:AS9A RS19925
gene id: 443218:AS9A_RS19925
uniprot id: F6EK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS08930
gene id: 443218:AS9A_RS08930
uniprot id: F6EMD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

443218:AS9A RS05885
gene id: 443218:AS9A_RS05885
uniprot id: F6EEH0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

443218:AS9A RS06180
gene id: 443218:AS9A_RS06180
uniprot id: F6EEM8
names: Similarity
messages: Belongs to the asparagine synthetase family.

443218:AS9A RS02950
gene id: 443218:AS9A_RS02950
uniprot id: F6EJL0
names: Cofactor
messages: Can also use Mn(2+) ion.

443218:AS9A RS14935
gene id: 443218:AS9A_RS14935
uniprot id: F6ELV4
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

443218:AS9A RS07715
gene id: 443218:AS9A_RS07715
uniprot id: F6EIY4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

443218:AS9A RS12425
gene id: 443218:AS9A_RS12425
uniprot id: F6EGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

443218:AS9A RS11490
gene id: 443218:AS9A_RS11490
uniprot id: F6ES16
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS11375
gene id: 443218:AS9A_RS11375
uniprot id: F6ERZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

443218:AS9A RS15555
gene id: 443218:AS9A_RS15555
uniprot id: F6ENL0
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS11475
gene id: 443218:AS9A_RS11475
uniprot id: F6ES13
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS15740
gene id: 443218:AS9A_RS15740
uniprot id: F6EP56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

443218:AS9A RS08290
gene id: 443218:AS9A_RS08290
uniprot id: F6EKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS06410
gene id: 443218:AS9A_RS06410
uniprot id: F6EFG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

443218:AS9A RS15580
gene id: 443218:AS9A_RS15580
uniprot id: F6ENL5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

443218:AS9A RS20075
gene id: 443218:AS9A_RS20075
uniprot id: F6EK90
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

443218:AS9A RS13525
gene id: 443218:AS9A_RS13525
uniprot id: F6EJ28
names: Similarity
messages: Belongs to the cytochrome P450 family.

443218:AS9A RS08775
gene id: 443218:AS9A_RS08775
uniprot id: F6ELL5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

443218:AS9A RS01410
gene id: 443218:AS9A_RS01410
uniprot id: F6EG45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

443218:AS9A RS08985
gene id: 443218:AS9A_RS08985
uniprot id: F6EME7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS17570
gene id: 443218:AS9A_RS17570
uniprot id: F6EEW8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

443218:AS9A RS05770
gene id: 443218:AS9A_RS05770
uniprot id: F6ERR6
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

443218:AS9A RS08845
gene id: 443218:AS9A_RS08845
uniprot id: F6EMB9
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS08295
gene id: 443218:AS9A_RS08295
uniprot id: F6EKN2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

443218:AS9A RS12535
gene id: 443218:AS9A_RS12535
uniprot id: F6EGJ7
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

443218:AS9A RS21215
gene id: 443218:AS9A_RS21215
uniprot id: F6EMX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

443218:AS9A RS15690
gene id: 443218:AS9A_RS15690
uniprot id: F6ENN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS03270
gene id: 443218:AS9A_RS03270
uniprot id: F6EKF3
names: Similarity
messages: Belongs to the GARS family.

443218:AS9A RS12845
gene id: 443218:AS9A_RS12845
uniprot id: F6EHD9
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS20470
gene id: 443218:AS9A_RS20470
uniprot id: F6EL48
names: Similarity
messages: Belongs to the YoeB family.

443218:AS9A RS00825
gene id: 443218:AS9A_RS00825
uniprot id: F6EF48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LigB/MhpB extradiol dioxygenase family.
messages: Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
messages: Homotetramer.

443218:AS9A RS06635
gene id: 443218:AS9A_RS06635
uniprot id: F6EGA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

443218:AS9A RS08055
gene id: 443218:AS9A_RS08055
uniprot id: F6EJU3
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

443218:AS9A RS15710
gene id: 443218:AS9A_RS15710
uniprot id: F6EP50
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

443218:AS9A RS03875
gene id: 443218:AS9A_RS03875
uniprot id: F6EM42
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS08770
gene id: 443218:AS9A_RS08770
uniprot id: F6ELL4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

443218:AS9A RS09125
gene id: 443218:AS9A_RS09125
uniprot id: F6EMH6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

443218:AS9A RS20705
gene id: 443218:AS9A_RS20705
uniprot id: F6ELY1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

443218:AS9A RS09880
gene id: 443218:AS9A_RS09880
uniprot id: F6EP22
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS02380
gene id: 443218:AS9A_RS02380
uniprot id: F6EIM0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

443218:AS9A RS12925
gene id: 443218:AS9A_RS12925
uniprot id: F6EHF6
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS10290
gene id: 443218:AS9A_RS10290
uniprot id: F6EPU6
names: Similarity
messages: Belongs to the universal stress protein A family.

443218:AS9A RS06990
gene id: 443218:AS9A_RS06990
uniprot id: F6EH61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

443218:AS9A RS19620
gene id: 443218:AS9A_RS19620
uniprot id: F6EJC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

443218:AS9A RS19665
gene id: 443218:AS9A_RS19665
uniprot id: F6EJC9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443218:AS9A RS05780
gene id: 443218:AS9A_RS05780
uniprot id: F6ERR8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

443218:AS9A RS19305
gene id: 443218:AS9A_RS19305
uniprot id: F6EII1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

443218:AS9A RS14750
gene id: 443218:AS9A_RS14750
uniprot id: F6ELR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS11640
gene id: 443218:AS9A_RS11640
uniprot id: F6EER3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS10790
gene id: 443218:AS9A_RS10790
uniprot id: F6EQZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

443218:AS9A RS13400
gene id: 443218:AS9A_RS13400
uniprot id: F6EJ02
names: Similarity
messages: Belongs to the CdaR family.

443218:AS9A RS22015
gene id: 443218:AS9A_RS22015
uniprot id: F6ESC1
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

443218:AS9A RS16700
gene id: 443218:AS9A_RS16700
uniprot id: F6EQQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS18635
gene id: 443218:AS9A_RS18635
uniprot id: F6EGU1
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

443218:AS9A RS09120
gene id: 443218:AS9A_RS09120
uniprot id: F6EMH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

443218:AS9A RS01825
gene id: 443218:AS9A_RS01825
uniprot id: F6EH10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

443218:AS9A RS06960
gene id: 443218:AS9A_RS06960
uniprot id: F6EH55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

443218:AS9A RS14965
gene id: 443218:AS9A_RS14965
uniprot id: F6EMK0
names: Similarity
messages: Belongs to the CFA/CMAS family.

443218:AS9A RS05605
gene id: 443218:AS9A_RS05605
uniprot id: F6ERN1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS15830
gene id: 443218:AS9A_RS15830
uniprot id: F6EP76
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

443218:AS9A RS05350
gene id: 443218:AS9A_RS05350
uniprot id: F6EQU4
names: Similarity
messages: Belongs to the peptidase C59 family.

443218:AS9A RS09085
gene id: 443218:AS9A_RS09085
uniprot id: F6EMG8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

443218:AS9A RS21880
gene id: 443218:AS9A_RS21880
uniprot id: F6EPF9
names: Similarity
messages: Belongs to the thioredoxin family.

443218:AS9A RS08080
gene id: 443218:AS9A_RS08080
uniprot id: F6EJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS13450
gene id: 443218:AS9A_RS13450
uniprot id: F6EJ13
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

443218:AS9A RS08070
gene id: 443218:AS9A_RS08070
uniprot id: F6EJU6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

443218:AS9A RS20830
gene id: 443218:AS9A_RS20830
uniprot id: F6EM09
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

443218:AS9A RS20195
gene id: 443218:AS9A_RS20195
uniprot id: F6EKB5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

443218:AS9A RS13300
gene id: 443218:AS9A_RS13300
uniprot id: F6EIA7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

443218:AS9A RS12280
gene id: 443218:AS9A_RS12280
uniprot id: F6EGE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

443218:AS9A RS11250
gene id: 443218:AS9A_RS11250
uniprot id: F6ERW5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

443218:AS9A RS10100
gene id: 443218:AS9A_RS10100
uniprot id: F6EPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS15030
gene id: 443218:AS9A_RS15030
uniprot id: F6EML3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

443218:AS9A RS03355
gene id: 443218:AS9A_RS03355
uniprot id: F6EKH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

443218:AS9A RS08765
gene id: 443218:AS9A_RS08765
uniprot id: F6ELL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

443218:AS9A RS16235
gene id: 443218:AS9A_RS16235
uniprot id: F6EQ09
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

443218:AS9A RS07830
gene id: 443218:AS9A_RS07830
uniprot id: F6EJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

443218:AS9A RS13990
gene id: 443218:AS9A_RS13990
uniprot id: F6EJZ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

443218:AS9A RS05345
gene id: 443218:AS9A_RS05345
uniprot id: F6EQU3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

443218:AS9A RS20350
gene id: 443218:AS9A_RS20350
uniprot id: F6EL24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

443218:AS9A RS02290
gene id: 443218:AS9A_RS02290
uniprot id: F6EHX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

443218:AS9A RS14230
gene id: 443218:AS9A_RS14230
uniprot id: F6EKS6
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

443218:AS9A RS11295
gene id: 443218:AS9A_RS11295
uniprot id: F6ERX4
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS06070
gene id: 443218:AS9A_RS06070
uniprot id: F6EEK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

443218:AS9A RS18280
gene id: 443218:AS9A_RS18280
uniprot id: F6EFZ1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

443218:AS9A RS17110
gene id: 443218:AS9A_RS17110
uniprot id: F6ERD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

443218:AS9A RS02240
gene id: 443218:AS9A_RS02240
uniprot id: F6EHW8
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS19265
gene id: 443218:AS9A_RS19265
uniprot id: F6EIH3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

443218:AS9A RS08780
gene id: 443218:AS9A_RS08780
uniprot id: F6ELL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

443218:AS9A RS21350
gene id: 443218:AS9A_RS21350
uniprot id: F6ENP1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

443218:AS9A RS01320
gene id: 443218:AS9A_RS01320
uniprot id: F6EG27
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS20130
gene id: 443218:AS9A_RS20130
uniprot id: F6EKA2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

443218:AS9A RS07315
gene id: 443218:AS9A_RS07315
uniprot id: F6EI18
names: Similarity
messages: Belongs to the UPF0434 family.

443218:AS9A RS13320
gene id: 443218:AS9A_RS13320
uniprot id: F6EIB1
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

443218:AS9A RS02480
gene id: 443218:AS9A_RS02480
uniprot id: F6EIN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

443218:AS9A RS14955
gene id: 443218:AS9A_RS14955
uniprot id: F6EMJ8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

443218:AS9A RS02945
gene id: 443218:AS9A_RS02945
uniprot id: F6EJK9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

443218:AS9A RS13895
gene id: 443218:AS9A_RS13895
uniprot id: F6EJX5
names: Similarity
messages: Belongs to the FGGY kinase family.

443218:AS9A RS09165
gene id: 443218:AS9A_RS09165
uniprot id: F6EMI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

443218:AS9A RS00535
gene id: 443218:AS9A_RS00535
uniprot id: F6EEB7
names: Similarity
messages: Belongs to the AccD/PCCB family.

443218:AS9A RS10825
gene id: 443218:AS9A_RS10825
uniprot id: F6ER00
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS17850
gene id: 443218:AS9A_RS17850
uniprot id: F6EF26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

443218:AS9A RS09160
gene id: 443218:AS9A_RS09160
uniprot id: F6EMI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

443218:AS9A RS07580
gene id: 443218:AS9A_RS07580
uniprot id: F6EIV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

443218:AS9A RS02565
gene id: 443218:AS9A_RS02565
uniprot id: F6EIQ6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

443218:AS9A RS16420
gene id: 443218:AS9A_RS16420
uniprot id: F6EQJ3
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

443218:AS9A RS14190
gene id: 443218:AS9A_RS14190
uniprot id: F6EKR8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS01180
gene id: 443218:AS9A_RS01180
uniprot id: F6EFZ9
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS17490
gene id: 443218:AS9A_RS17490
uniprot id: F6ES85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

443218:AS9A RS03675
gene id: 443218:AS9A_RS03675
uniprot id: F6ELB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

443218:AS9A RS10445
gene id: 443218:AS9A_RS10445
uniprot id: F6EQC0
names: Similarity
messages: Belongs to the TmoD/XamoD family.

443218:AS9A RS09610
gene id: 443218:AS9A_RS09610
uniprot id: F6ENG1
names: Similarity
messages: Belongs to the HypD family.

443218:AS9A RS07950
gene id: 443218:AS9A_RS07950
uniprot id: F6EJS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

443218:AS9A RS20175
gene id: 443218:AS9A_RS20175
uniprot id: F6EKB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

443218:AS9A RS03750
gene id: 443218:AS9A_RS03750
uniprot id: F6ELD1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS17040
gene id: 443218:AS9A_RS17040
uniprot id: F6ERC1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

443218:AS9A RS15280
gene id: 443218:AS9A_RS15280
uniprot id: F6EMR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

443218:AS9A RS05295
gene id: 443218:AS9A_RS05295
uniprot id: F6EQT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

443218:AS9A RS17375
gene id: 443218:AS9A_RS17375
uniprot id: F6ES62
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS17520
gene id: 443218:AS9A_RS17520
uniprot id: F6ES91
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

443218:AS9A RS19820
gene id: 443218:AS9A_RS19820
uniprot id: F6EK37
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

443218:AS9A RS02355
gene id: 443218:AS9A_RS02355
uniprot id: F6EIL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

443218:AS9A RS18930
gene id: 443218:AS9A_RS18930
uniprot id: F6EHN0
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS01725
gene id: 443218:AS9A_RS01725
uniprot id: F6EGZ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

443218:AS9A RS07160
gene id: 443218:AS9A_RS07160
uniprot id: F6EHY6
names: Similarity
messages: Belongs to the thioredoxin family.

443218:AS9A RS02430
gene id: 443218:AS9A_RS02430
uniprot id: F6EIN0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

443218:AS9A RS21805
gene id: 443218:AS9A_RS21805
uniprot id: F6EPE3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS06580
gene id: 443218:AS9A_RS06580
uniprot id: F6EG88
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS07225
gene id: 443218:AS9A_RS07225
uniprot id: F6EI00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

443218:AS9A RS13350
gene id: 443218:AS9A_RS13350
uniprot id: F6EIB7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

443218:AS9A RS07290
gene id: 443218:AS9A_RS07290
uniprot id: F6EI13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

443218:AS9A RS17530
gene id: 443218:AS9A_RS17530
uniprot id: F6ES93
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

443218:AS9A RS02115
gene id: 443218:AS9A_RS02115
uniprot id: F6EHU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

443218:AS9A RS10645
gene id: 443218:AS9A_RS10645
uniprot id: F6EQG5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443218:AS9A RS07425
gene id: 443218:AS9A_RS07425
uniprot id: F6EI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

443218:AS9A RS03785
gene id: 443218:AS9A_RS03785
uniprot id: F6ELD8
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

443218:AS9A RS07545
gene id: 443218:AS9A_RS07545
uniprot id: F6EIU8
names: Similarity
messages: Belongs to the P(II) protein family.

443218:AS9A RS01520
gene id: 443218:AS9A_RS01520
uniprot id: F6EG67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

443218:AS9A RS18270
gene id: 443218:AS9A_RS18270
uniprot id: F6EFY9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

443218:AS9A RS21835
gene id: 443218:AS9A_RS21835
uniprot id: F6EPF0
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS09595
gene id: 443218:AS9A_RS09595
uniprot id: F6ENF8
names: Similarity
messages: Belongs to the HupF/HypC family.

443218:AS9A RS17160
gene id: 443218:AS9A_RS17160
uniprot id: F6ES21
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS02580
gene id: 443218:AS9A_RS02580
uniprot id: F6EIQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
messages: Homodimer.

443218:AS9A RS02335
gene id: 443218:AS9A_RS02335
uniprot id: F6EIL1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

443218:AS9A RS13630
gene id: 443218:AS9A_RS13630
uniprot id: F6EJ48
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

443218:AS9A RS11520
gene id: 443218:AS9A_RS11520
uniprot id: F6EEN7
names: Similarity
messages: Belongs to the CdaR family.

443218:AS9A RS18085
gene id: 443218:AS9A_RS18085
uniprot id: F6EFU7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

443218:AS9A RS18740
gene id: 443218:AS9A_RS18740
uniprot id: F6EHI7
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

443218:AS9A RS04590
gene id: 443218:AS9A_RS04590
uniprot id: F6EN83
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443218:AS9A RS09135
gene id: 443218:AS9A_RS09135
uniprot id: F6EMH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

443218:AS9A RS01065
gene id: 443218:AS9A_RS01065
uniprot id: F6EF98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

443218:AS9A RS12195
gene id: 443218:AS9A_RS12195
uniprot id: F6EFP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

443218:AS9A RS01690
gene id: 443218:AS9A_RS01690
uniprot id: F6EGY2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

443218:AS9A RS05370
gene id: 443218:AS9A_RS05370
uniprot id: F6EQU9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

443218:AS9A RS22685
gene id: 443218:AS9A_RS22685
uniprot id: F6EPS0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

443218:AS9A RS07530
gene id: 443218:AS9A_RS07530
uniprot id: F6EIU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

443218:AS9A RS02385
gene id: 443218:AS9A_RS02385
uniprot id: F6EIM1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

443218:AS9A RS15745
gene id: 443218:AS9A_RS15745
uniprot id: F6EP57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

443218:AS9A RS19435
gene id: 443218:AS9A_RS19435
uniprot id: F6EJ82
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

443218:AS9A RS15655
gene id: 443218:AS9A_RS15655
uniprot id: F6ENM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

443218:AS9A RS21895
gene id: 443218:AS9A_RS21895
uniprot id: F6EPG2
names: Similarity
messages: Belongs to the ParB family.

443218:AS9A RS19185
gene id: 443218:AS9A_RS19185
uniprot id: F6EIF5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

443218:AS9A RS17120
gene id: 443218:AS9A_RS17120
uniprot id: F6ERD9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

443218:AS9A RS02195
gene id: 443218:AS9A_RS02195
uniprot id: F6EHV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

443218:AS9A RS04600
gene id: 443218:AS9A_RS04600
uniprot id: F6EPG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS19220
gene id: 443218:AS9A_RS19220
uniprot id: F6EIG4
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS23040
gene id: 443218:AS9A_RS23040
uniprot id: F6ESM2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

443218:AS9A RS05785
gene id: 443218:AS9A_RS05785
uniprot id: F6ERR9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

443218:AS9A RS01795
gene id: 443218:AS9A_RS01795
uniprot id: F6EH04
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

443218:AS9A RS15420
gene id: 443218:AS9A_RS15420
uniprot id: F6ENI1
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS06195
gene id: 443218:AS9A_RS06195
uniprot id: F6EEN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS00675
gene id: 443218:AS9A_RS00675
uniprot id: F6EEE5
names: Similarity
messages: Belongs to the isochorismate synthase family.

443218:AS9A RS14295
gene id: 443218:AS9A_RS14295
uniprot id: F6EKT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

443218:AS9A RS20975
gene id: 443218:AS9A_RS20975
uniprot id: F6EMS9
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS14990
gene id: 443218:AS9A_RS14990
uniprot id: F6EMK5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

443218:AS9A RS08530
gene id: 443218:AS9A_RS08530
uniprot id: F6ELG9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

443218:AS9A RS20650
gene id: 443218:AS9A_RS20650
uniprot id: F6ELX0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS06125
gene id: 443218:AS9A_RS06125
uniprot id: F6EEL7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

443218:AS9A RS07005
gene id: 443218:AS9A_RS07005
uniprot id: F6EH64
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

443218:AS9A RS17075
gene id: 443218:AS9A_RS17075
uniprot id: F6ERC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

443218:AS9A RS20210
gene id: 443218:AS9A_RS20210
uniprot id: F6EKZ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS11890
gene id: 443218:AS9A_RS11890
uniprot id: F6EFI7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

443218:AS9A RS16795
gene id: 443218:AS9A_RS16795
uniprot id: F6ER71
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS20000
gene id: 443218:AS9A_RS20000
uniprot id: F6EK73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

443218:AS9A RS07185
gene id: 443218:AS9A_RS07185
uniprot id: F6EHZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

443218:AS9A RS01955
gene id: 443218:AS9A_RS01955
uniprot id: F6EHQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

443218:AS9A RS20880
gene id: 443218:AS9A_RS20880
uniprot id: F6EM19
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS00565
gene id: 443218:AS9A_RS00565
uniprot id: F6EEC3
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

443218:AS9A RS09185
gene id: 443218:AS9A_RS09185
uniprot id: F6EMI7
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS14410
gene id: 443218:AS9A_RS14410
uniprot id: F6EKW2
names: Similarity
messages: Belongs to the cytochrome P450 family.

443218:AS9A RS14120
gene id: 443218:AS9A_RS14120
uniprot id: F6EK26
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).

443218:AS9A RS01945
gene id: 443218:AS9A_RS01945
uniprot id: F6EHQ8
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS05820
gene id: 443218:AS9A_RS05820
uniprot id: F6ERS7
names: Similarity
messages: Belongs to the PstS family.

443218:AS9A RS04690
gene id: 443218:AS9A_RS04690
uniprot id: F6EPI7
names: Similarity
messages: Belongs to the GcvT family.

443218:AS9A RS05310
gene id: 443218:AS9A_RS05310
uniprot id: F6EQT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS13785
gene id: 443218:AS9A_RS13785
uniprot id: F6EJ79
names: Similarity
messages: Belongs to the cytochrome P450 family.

443218:AS9A RS09300
gene id: 443218:AS9A_RS09300
uniprot id: F6ENA0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

443218:AS9A RS02255
gene id: 443218:AS9A_RS02255
uniprot id: F6EHX1
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS07645
gene id: 443218:AS9A_RS07645
uniprot id: F6EIX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

443218:AS9A RS08885
gene id: 443218:AS9A_RS08885
uniprot id: F6EMC7
names: Subcellular Location Annotation
messages: cell wall

443218:AS9A RS18355
gene id: 443218:AS9A_RS18355
uniprot id: F6EGN2
names: Similarity
messages: Belongs to the AccD/PCCB family.

443218:AS9A RS24815
gene id: 443218:AS9A_RS24815
uniprot id: F6EGR5
names: Similarity
messages: Belongs to the peptidase C40 family.

443218:AS9A RS17455
gene id: 443218:AS9A_RS17455
uniprot id: F6ES79
names: Function
names: Similarity
messages: Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
messages: Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia.

443218:AS9A RS08250
gene id: 443218:AS9A_RS08250
uniprot id: F6EKM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

443218:AS9A RS12495
gene id: 443218:AS9A_RS12495
uniprot id: F6EGI9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

443218:AS9A RS22485
gene id: 443218:AS9A_RS22485
uniprot id: F6ESP2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

443218:AS9A RS14425
gene id: 443218:AS9A_RS14425
uniprot id: F6EKW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS08855
gene id: 443218:AS9A_RS08855
uniprot id: F6EMC1
names: Similarity
messages: Belongs to the FPG family.

443218:AS9A RS01085
gene id: 443218:AS9A_RS01085
uniprot id: F6EFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

443218:AS9A RS03460
gene id: 443218:AS9A_RS03460
uniprot id: F6EKJ1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

443218:AS9A RS00240
gene id: 443218:AS9A_RS00240
uniprot id: F6ERI7
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS07330
gene id: 443218:AS9A_RS07330
uniprot id: F6EI21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

443218:AS9A RS16820
gene id: 443218:AS9A_RS16820
uniprot id: F6ER76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

443218:AS9A RS18330
gene id: 443218:AS9A_RS18330
uniprot id: F6EGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

443218:AS9A RS01995
gene id: 443218:AS9A_RS01995
uniprot id: F6EHR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

443218:AS9A RS17180
gene id: 443218:AS9A_RS17180
uniprot id: F6ES25
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

443218:AS9A RS16690
gene id: 443218:AS9A_RS16690
uniprot id: F6EQQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

443218:AS9A RS09725
gene id: 443218:AS9A_RS09725
uniprot id: F6ENZ0
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

443218:AS9A RS09330
gene id: 443218:AS9A_RS09330
uniprot id: F6ENA6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

443218:AS9A RS01990
gene id: 443218:AS9A_RS01990
uniprot id: F6EHR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

443218:AS9A RS03885
gene id: 443218:AS9A_RS03885
uniprot id: F6EM44
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

443218:AS9A RS05230
gene id: 443218:AS9A_RS05230
uniprot id: F6EQS2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

443218:AS9A RS07600
gene id: 443218:AS9A_RS07600
uniprot id: F6EIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

443218:AS9A RS12550
gene id: 443218:AS9A_RS12550
uniprot id: F6EGK1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS19235
gene id: 443218:AS9A_RS19235
uniprot id: F6EIG7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

443218:AS9A RS17370
gene id: 443218:AS9A_RS17370
uniprot id: F6ES61
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

443218:AS9A RS10105
gene id: 443218:AS9A_RS10105
uniprot id: F6EPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS13075
gene id: 443218:AS9A_RS13075
uniprot id: F6EI58
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS02855
gene id: 443218:AS9A_RS02855
uniprot id: F6EJJ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS21325
gene id: 443218:AS9A_RS21325
uniprot id: F6EN01
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

443218:AS9A RS02900
gene id: 443218:AS9A_RS02900
uniprot id: F6EJK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS16120
gene id: 443218:AS9A_RS16120
uniprot id: F6EPY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

443218:AS9A RS17015
gene id: 443218:AS9A_RS17015
uniprot id: F6ERB6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

443218:AS9A RS06485
gene id: 443218:AS9A_RS06485
uniprot id: F6EFH8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

443218:AS9A RS06300
gene id: 443218:AS9A_RS06300
uniprot id: F6EFD8
names: Caution
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS09545
gene id: 443218:AS9A_RS09545
uniprot id: F6ENE8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

443218:AS9A RS01585
gene id: 443218:AS9A_RS01585
uniprot id: F6EGV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS14465
gene id: 443218:AS9A_RS14465
uniprot id: F6EKX3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

443218:AS9A RS02590
gene id: 443218:AS9A_RS02590
uniprot id: F6EIR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

443218:AS9A RS21330
gene id: 443218:AS9A_RS21330
uniprot id: F6EN02
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

443218:AS9A RS00380
gene id: 443218:AS9A_RS00380
uniprot id: F6ERL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

443218:AS9A RS14650
gene id: 443218:AS9A_RS14650
uniprot id: F6ELP2
names: Similarity
messages: Belongs to the pirin family.

443218:AS9A RS00840
gene id: 443218:AS9A_RS00840
uniprot id: F6EF52
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

443218:AS9A RS05495
gene id: 443218:AS9A_RS05495
uniprot id: F6EQX5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

443218:AS9A RS01965
gene id: 443218:AS9A_RS01965
uniprot id: F6EHR1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

443218:AS9A RS09860
gene id: 443218:AS9A_RS09860
uniprot id: F6EP18
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

443218:AS9A RS15590
gene id: 443218:AS9A_RS15590
uniprot id: F6ENL7
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

443218:AS9A RS13880
gene id: 443218:AS9A_RS13880
uniprot id: F6EJX2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

443218:AS9A RS15370
gene id: 443218:AS9A_RS15370
uniprot id: F6ENH0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS10885
gene id: 443218:AS9A_RS10885
uniprot id: F6ER13
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

443218:AS9A RS21410
gene id: 443218:AS9A_RS21410
uniprot id: F6ENQ5
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

443218:AS9A RS12230
gene id: 443218:AS9A_RS12230
uniprot id: F6EFQ5
names: Similarity
messages: Belongs to the AHA1 family.

443218:AS9A RS20500
gene id: 443218:AS9A_RS20500
uniprot id: F6EL56
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

443218:AS9A RS15355
gene id: 443218:AS9A_RS15355
uniprot id: F6ENG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

443218:AS9A RS00275
gene id: 443218:AS9A_RS00275
uniprot id: F6ERJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS21660
gene id: 443218:AS9A_RS21660
uniprot id: F6ENV7
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

443218:AS9A RS10020
gene id: 443218:AS9A_RS10020
uniprot id: F6EPP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

443218:AS9A RS14940
gene id: 443218:AS9A_RS14940
uniprot id: F6ELV5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

443218:AS9A RS04290
gene id: 443218:AS9A_RS04290
uniprot id: F6EN21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

443218:AS9A RS09050
gene id: 443218:AS9A_RS09050
uniprot id: F6EMG0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

443218:AS9A RS12800
gene id: 443218:AS9A_RS12800
uniprot id: F6EHC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS20840
gene id: 443218:AS9A_RS20840
uniprot id: F6EM11
names: Similarity
messages: Belongs to the FGGY kinase family.

443218:AS9A RS08145
gene id: 443218:AS9A_RS08145
uniprot id: F6EKK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

443218:AS9A RS14305
gene id: 443218:AS9A_RS14305
uniprot id: F6EKU1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

443218:AS9A RS19800
gene id: 443218:AS9A_RS19800
uniprot id: F6EJF8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

443218:AS9A RS19300
gene id: 443218:AS9A_RS19300
uniprot id: F6EII0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

443218:AS9A RS14050
gene id: 443218:AS9A_RS14050
uniprot id: F6EK10
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS05555
gene id: 443218:AS9A_RS05555
uniprot id: F6EQY7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

443218:AS9A RS08025
gene id: 443218:AS9A_RS08025
uniprot id: F6EJT7
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS03895
gene id: 443218:AS9A_RS03895
uniprot id: F6EM46
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

443218:AS9A RS10250
gene id: 443218:AS9A_RS10250
uniprot id: F6EPT8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

443218:AS9A RS13385
gene id: 443218:AS9A_RS13385
uniprot id: F6EIC4
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS11870
gene id: 443218:AS9A_RS11870
uniprot id: F6EEW2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

443218:AS9A RS06010
gene id: 443218:AS9A_RS06010
uniprot id: F6EEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

443218:AS9A RS16115
gene id: 443218:AS9A_RS16115
uniprot id: F6EPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

443218:AS9A RS15220
gene id: 443218:AS9A_RS15220
uniprot id: F6EMQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

443218:AS9A RS07910
gene id: 443218:AS9A_RS07910
uniprot id: F6EJR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

443218:AS9A RS02345
gene id: 443218:AS9A_RS02345
uniprot id: F6EIL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

443218:AS9A RS07375
gene id: 443218:AS9A_RS07375
uniprot id: F6EI28
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

443218:AS9A RS15360
gene id: 443218:AS9A_RS15360
uniprot id: F6ENG8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

443218:AS9A RS06935
gene id: 443218:AS9A_RS06935
uniprot id: F6EH50
names: Similarity
messages: Belongs to the peptidase S8 family.

443218:AS9A RS19510
gene id: 443218:AS9A_RS19510
uniprot id: F6EJ97
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

443218:AS9A RS07570
gene id: 443218:AS9A_RS07570
uniprot id: F6EIV4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

443218:AS9A RS02720
gene id: 443218:AS9A_RS02720
uniprot id: F6EJG5
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS08050
gene id: 443218:AS9A_RS08050
uniprot id: F6EJU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS16455
gene id: 443218:AS9A_RS16455
uniprot id: F6EQK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS16960
gene id: 443218:AS9A_RS16960
uniprot id: F6ERA5
names: Similarity
messages: Belongs to the CsoR family.

443218:AS9A RS16215
gene id: 443218:AS9A_RS16215
uniprot id: F6EQ04
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily.
messages: Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine.

443218:AS9A RS01150
gene id: 443218:AS9A_RS01150
uniprot id: F6EFB5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

443218:AS9A RS19065
gene id: 443218:AS9A_RS19065
uniprot id: F6EID1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

443218:AS9A RS09265
gene id: 443218:AS9A_RS09265
uniprot id: F6EN92
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

443218:AS9A RS21390
gene id: 443218:AS9A_RS21390
uniprot id: F6ENQ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS22420
gene id: 443218:AS9A_RS22420
uniprot id: F6ESM8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

443218:AS9A RS04560
gene id: 443218:AS9A_RS04560
uniprot id: F6EN77
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS07765
gene id: 443218:AS9A_RS07765
uniprot id: F6EIZ4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

443218:AS9A RS01705
gene id: 443218:AS9A_RS01705
uniprot id: F6EGY5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

443218:AS9A RS07305
gene id: 443218:AS9A_RS07305
uniprot id: F6EI16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

443218:AS9A RS14625
gene id: 443218:AS9A_RS14625
uniprot id: F6ELN7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

443218:AS9A RS13045
gene id: 443218:AS9A_RS13045
uniprot id: F6EI52
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

443218:AS9A RS07555
gene id: 443218:AS9A_RS07555
uniprot id: F6EIV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

443218:AS9A RS05545
gene id: 443218:AS9A_RS05545
uniprot id: F6EQY5
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS10930
gene id: 443218:AS9A_RS10930
uniprot id: F6ER23
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS13185
gene id: 443218:AS9A_RS13185
uniprot id: F6EI81
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS16465
gene id: 443218:AS9A_RS16465
uniprot id: F6EQK2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS06445
gene id: 443218:AS9A_RS06445
uniprot id: F6EFH0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

443218:AS9A RS09095
gene id: 443218:AS9A_RS09095
uniprot id: F6EMH0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

443218:AS9A RS08310
gene id: 443218:AS9A_RS08310
uniprot id: F6EKN5
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS17845
gene id: 443218:AS9A_RS17845
uniprot id: F6EF25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

443218:AS9A RS21190
gene id: 443218:AS9A_RS21190
uniprot id: F6EMX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

443218:AS9A RS17870
gene id: 443218:AS9A_RS17870
uniprot id: F6EF30
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS14765
gene id: 443218:AS9A_RS14765
uniprot id: F6ELR6
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

443218:AS9A RS05060
gene id: 443218:AS9A_RS05060
uniprot id: F6EQ76
names: Subcellular Location Annotation
messages: Secreted

443218:AS9A RS00025
gene id: 443218:AS9A_RS00025
uniprot id: F6ERE5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

443218:AS9A RS02585
gene id: 443218:AS9A_RS02585
uniprot id: F6EIR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

443218:AS9A RS11130
gene id: 443218:AS9A_RS11130
uniprot id: F6ERU0
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

443218:AS9A RS04135
gene id: 443218:AS9A_RS04135
uniprot id: F6EM99
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS01435
gene id: 443218:AS9A_RS01435
uniprot id: F6EG50
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

443218:AS9A RS10060
gene id: 443218:AS9A_RS10060
uniprot id: F6EPP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS08705
gene id: 443218:AS9A_RS08705
uniprot id: F6ELK1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

443218:AS9A RS01105
gene id: 443218:AS9A_RS01105
uniprot id: F6EFA6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

443218:AS9A RS18645
gene id: 443218:AS9A_RS18645
uniprot id: F6EGU3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

443218:AS9A RS15315
gene id: 443218:AS9A_RS15315
uniprot id: F6EMS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

443218:AS9A RS04435
gene id: 443218:AS9A_RS04435
uniprot id: F6EN52
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS17345
gene id: 443218:AS9A_RS17345
uniprot id: F6ES56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

443218:AS9A RS19810
gene id: 443218:AS9A_RS19810
uniprot id: F6EJG0
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS01020
gene id: 443218:AS9A_RS01020
uniprot id: F6EF90
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS15430
gene id: 443218:AS9A_RS15430
uniprot id: F6ENI3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

443218:AS9A RS01460
gene id: 443218:AS9A_RS01460
uniprot id: F6EG55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

443218:AS9A RS08970
gene id: 443218:AS9A_RS08970
uniprot id: F6EME4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

443218:AS9A RS10940
gene id: 443218:AS9A_RS10940
uniprot id: F6ER25
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS17140
gene id: 443218:AS9A_RS17140
uniprot id: F6ERE3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

443218:AS9A RS02615
gene id: 443218:AS9A_RS02615
uniprot id: F6EIR6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS22025
gene id: 443218:AS9A_RS22025
uniprot id: F6ESC4
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

443218:AS9A RS07915
gene id: 443218:AS9A_RS07915
uniprot id: F6EJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

443218:AS9A RS06095
gene id: 443218:AS9A_RS06095
uniprot id: F6EEL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

443218:AS9A RS19845
gene id: 443218:AS9A_RS19845
uniprot id: F6EK42
names: Similarity
messages: Belongs to the pirin family.

443218:AS9A RS15910
gene id: 443218:AS9A_RS15910
uniprot id: F6EP96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

443218:AS9A RS04125
gene id: 443218:AS9A_RS04125
uniprot id: F6EM97
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS12935
gene id: 443218:AS9A_RS12935
uniprot id: F6EHF8
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

443218:AS9A RS11935
gene id: 443218:AS9A_RS11935
uniprot id: F6EFJ6
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS03210
gene id: 443218:AS9A_RS03210
uniprot id: F6EKE2
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS15515
gene id: 443218:AS9A_RS15515
uniprot id: F6ENK2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS15650
gene id: 443218:AS9A_RS15650
uniprot id: F6ENM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

443218:AS9A RS05710
gene id: 443218:AS9A_RS05710
uniprot id: F6ERQ3
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

443218:AS9A RS12450
gene id: 443218:AS9A_RS12450
uniprot id: F6EGI0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS04795
gene id: 443218:AS9A_RS04795
uniprot id: F6EPK9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

443218:AS9A RS14505
gene id: 443218:AS9A_RS14505
uniprot id: F6EKY1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

443218:AS9A RS05280
gene id: 443218:AS9A_RS05280
uniprot id: F6EQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

443218:AS9A RS15235
gene id: 443218:AS9A_RS15235
uniprot id: F6EMQ6
names: Similarity
messages: Belongs to the CdaR family.

443218:AS9A RS13410
gene id: 443218:AS9A_RS13410
uniprot id: F6EJ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

443218:AS9A RS07900
gene id: 443218:AS9A_RS07900
uniprot id: F6EJR0
names: Similarity
messages: Belongs to the ribF family.

443218:AS9A RS11675
gene id: 443218:AS9A_RS11675
uniprot id: F6EES1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

443218:AS9A RS16510
gene id: 443218:AS9A_RS16510
uniprot id: F6EQL2
names: Similarity
messages: Belongs to the peptidase S1C family.

443218:AS9A RS12110
gene id: 443218:AS9A_RS12110
uniprot id: F6EFN1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

443218:AS9A RS05455
gene id: 443218:AS9A_RS05455
uniprot id: F6EQW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

443218:AS9A RS21535
gene id: 443218:AS9A_RS21535
uniprot id: F6ENT1
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS06570
gene id: 443218:AS9A_RS06570
uniprot id: F6EG85
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

443218:AS9A RS19805
gene id: 443218:AS9A_RS19805
uniprot id: F6EJF9
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

443218:AS9A RS04495
gene id: 443218:AS9A_RS04495
uniprot id: F6EN64
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

443218:AS9A RS21875
gene id: 443218:AS9A_RS21875
uniprot id: F6EPF8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

443218:AS9A RS16090
gene id: 443218:AS9A_RS16090
uniprot id: F6EPX5
names: Similarity
messages: Belongs to the LOG family.

443218:AS9A RS22525
gene id: 443218:AS9A_RS22525
uniprot id: F6EGW6
names: Similarity
messages: Belongs to the asp23 family.

443218:AS9A RS20885
gene id: 443218:AS9A_RS20885
uniprot id: F6EM20
names: Similarity
messages: Belongs to the creatininase superfamily.

443218:AS9A RS07990
gene id: 443218:AS9A_RS07990
uniprot id: F6EJS8
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS20720
gene id: 443218:AS9A_RS20720
uniprot id: F6ELY6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

443218:AS9A RS08305
gene id: 443218:AS9A_RS08305
uniprot id: F6EKN4
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS20455
gene id: 443218:AS9A_RS20455
uniprot id: F6EL45
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

443218:AS9A RS19605
gene id: 443218:AS9A_RS19605
uniprot id: F6EJB7
names: Similarity
messages: Belongs to the MmpS family.

443218:AS9A RS07650
gene id: 443218:AS9A_RS07650
uniprot id: F6EIX1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS18685
gene id: 443218:AS9A_RS18685
uniprot id: F6EHH6
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS11780
gene id: 443218:AS9A_RS11780
uniprot id: F6EEU3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

443218:AS9A RS05860
gene id: 443218:AS9A_RS05860
uniprot id: F6ERT5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

443218:AS9A RS13220
gene id: 443218:AS9A_RS13220
uniprot id: F6EI88
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

443218:AS9A RS17115
gene id: 443218:AS9A_RS17115
uniprot id: F6ERD8
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS14265
gene id: 443218:AS9A_RS14265
uniprot id: F6EKT3
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS12270
gene id: 443218:AS9A_RS12270
uniprot id: F6EFR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

443218:AS9A RS13975
gene id: 443218:AS9A_RS13975
uniprot id: F6EJZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

443218:AS9A RS00450
gene id: 443218:AS9A_RS00450
uniprot id: F6EEA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

443218:AS9A RS22490
gene id: 443218:AS9A_RS22490
uniprot id: F6ERI5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

443218:AS9A RS05335
gene id: 443218:AS9A_RS05335
uniprot id: F6EQU1
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

443218:AS9A RS20620
gene id: 443218:AS9A_RS20620
uniprot id: F6ELW5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS09210
gene id: 443218:AS9A_RS09210
uniprot id: F6EMJ2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

443218:AS9A RS17885
gene id: 443218:AS9A_RS17885
uniprot id: F6EF34
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS02295
gene id: 443218:AS9A_RS02295
uniprot id: F6EHY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

443218:AS9A RS19520
gene id: 443218:AS9A_RS19520
uniprot id: F6EJ99
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

443218:AS9A RS02395
gene id: 443218:AS9A_RS02395
uniprot id: F6EIM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

443218:AS9A RS08445
gene id: 443218:AS9A_RS08445
uniprot id: F6ELF1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

443218:AS9A RS04145
gene id: 443218:AS9A_RS04145
uniprot id: F6EMA1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

443218:AS9A RS19110
gene id: 443218:AS9A_RS19110
uniprot id: F6EID9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS08185
gene id: 443218:AS9A_RS08185
uniprot id: F6EKK9
names: Similarity
messages: Belongs to the PspA/IM30 family.

443218:AS9A RS01115
gene id: 443218:AS9A_RS01115
uniprot id: F6EFA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS16535
gene id: 443218:AS9A_RS16535
uniprot id: F6EQL7
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS01465
gene id: 443218:AS9A_RS01465
uniprot id: F6EG56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

443218:AS9A RS15165
gene id: 443218:AS9A_RS15165
uniprot id: F6EMP2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS10150
gene id: 443218:AS9A_RS10150
uniprot id: F6EPR7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

443218:AS9A RS15105
gene id: 443218:AS9A_RS15105
uniprot id: F6EMM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

443218:AS9A RS14400
gene id: 443218:AS9A_RS14400
uniprot id: F6EKW0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

443218:AS9A RS02700
gene id: 443218:AS9A_RS02700
uniprot id: F6EJG1
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

443218:AS9A RS12120
gene id: 443218:AS9A_RS12120
uniprot id: F6EFN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS17640
gene id: 443218:AS9A_RS17640
uniprot id: F6EEY3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

443218:AS9A RS16790
gene id: 443218:AS9A_RS16790
uniprot id: F6ER70
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS18150
gene id: 443218:AS9A_RS18150
uniprot id: F6EFW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

443218:AS9A RS15340
gene id: 443218:AS9A_RS15340
uniprot id: F6ENG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

443218:AS9A RS15550
gene id: 443218:AS9A_RS15550
uniprot id: F6ENK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

443218:AS9A RS20465
gene id: 443218:AS9A_RS20465
uniprot id: F6EL47
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

443218:AS9A RS19890
gene id: 443218:AS9A_RS19890
uniprot id: F6EK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS08470
gene id: 443218:AS9A_RS08470
uniprot id: F6ELF6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

443218:AS9A RS14130
gene id: 443218:AS9A_RS14130
uniprot id: F6EK28
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

443218:AS9A RS08980
gene id: 443218:AS9A_RS08980
uniprot id: F6EME6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

443218:AS9A RS08160
gene id: 443218:AS9A_RS08160
uniprot id: F6EKK4
names: Similarity
messages: Belongs to the YciI family.

443218:AS9A RS10050
gene id: 443218:AS9A_RS10050
uniprot id: F6EPP6
names: Similarity
messages: Belongs to the UreD family.

443218:AS9A RS14245
gene id: 443218:AS9A_RS14245
uniprot id: F6EKS9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

443218:AS9A RS19690
gene id: 443218:AS9A_RS19690
uniprot id: F6EJD4
names: Similarity
messages: Belongs to the universal stress protein A family.

443218:AS9A RS01125
gene id: 443218:AS9A_RS01125
uniprot id: F6EFB0
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS05465
gene id: 443218:AS9A_RS05465
uniprot id: F6EQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS19640
gene id: 443218:AS9A_RS19640
uniprot id: F6EJC4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS12515
gene id: 443218:AS9A_RS12515
uniprot id: F6EGJ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS02715
gene id: 443218:AS9A_RS02715
uniprot id: F6EJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS15865
gene id: 443218:AS9A_RS15865
uniprot id: F6EP85
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

443218:AS9A RS13545
gene id: 443218:AS9A_RS13545
uniprot id: F6EJ32
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

443218:AS9A RS13275
gene id: 443218:AS9A_RS13275
uniprot id: F6EIA1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

443218:AS9A RS14455
gene id: 443218:AS9A_RS14455
uniprot id: F6EKX1
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

443218:AS9A RS08335
gene id: 443218:AS9A_RS08335
uniprot id: F6EKP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

443218:AS9A RS19250
gene id: 443218:AS9A_RS19250
uniprot id: F6EIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

443218:AS9A RS02350
gene id: 443218:AS9A_RS02350
uniprot id: F6EIL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

443218:AS9A RS04905
gene id: 443218:AS9A_RS04905
uniprot id: F6EPN1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

443218:AS9A RS14145
gene id: 443218:AS9A_RS14145
uniprot id: F6EK31
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS18165
gene id: 443218:AS9A_RS18165
uniprot id: F6EFW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

443218:AS9A RS21595
gene id: 443218:AS9A_RS21595
uniprot id: F6ENU4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

443218:AS9A RS06550
gene id: 443218:AS9A_RS06550
uniprot id: F6EG81
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

443218:AS9A RS08465
gene id: 443218:AS9A_RS08465
uniprot id: F6ELF5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

443218:AS9A RS06080
gene id: 443218:AS9A_RS06080
uniprot id: F6EEK8
names: Similarity
messages: Belongs to the glutamine synthetase family.

443218:AS9A RS18410
gene id: 443218:AS9A_RS18410
uniprot id: F6EGP3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

443218:AS9A RS15410
gene id: 443218:AS9A_RS15410
uniprot id: F6ENH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS15630
gene id: 443218:AS9A_RS15630
uniprot id: F6ENM3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

443218:AS9A RS11850
gene id: 443218:AS9A_RS11850
uniprot id: F6EEV8
names: Similarity
messages: Belongs to the glutamate synthase family.

443218:AS9A RS09875
gene id: 443218:AS9A_RS09875
uniprot id: F6EP21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

443218:AS9A RS18760
gene id: 443218:AS9A_RS18760
uniprot id: F6EHJ1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

443218:AS9A RS18585
gene id: 443218:AS9A_RS18585
uniprot id: F6EGT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

443218:AS9A RS20310
gene id: 443218:AS9A_RS20310
uniprot id: F6EL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS03090
gene id: 443218:AS9A_RS03090
uniprot id: F6EKB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

443218:AS9A RS09305
gene id: 443218:AS9A_RS09305
uniprot id: F6ENA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS12350
gene id: 443218:AS9A_RS12350
uniprot id: F6EGF5
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

443218:AS9A RS21430
gene id: 443218:AS9A_RS21430
uniprot id: F6ENQ9
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS10670
gene id: 443218:AS9A_RS10670
uniprot id: F6EQH1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

443218:AS9A RS12670
gene id: 443218:AS9A_RS12670
uniprot id: F6EHA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS13790
gene id: 443218:AS9A_RS13790
uniprot id: F6EJ80
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

443218:AS9A RS02790
gene id: 443218:AS9A_RS02790
uniprot id: F6EJI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

443218:AS9A RS02845
gene id: 443218:AS9A_RS02845
uniprot id: F6EJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

443218:AS9A RS15350
gene id: 443218:AS9A_RS15350
uniprot id: F6ENG6
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS22835
gene id: 443218:AS9A_RS22835
uniprot id: F6EP99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS01215
gene id: 443218:AS9A_RS01215
uniprot id: F6EG07
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS09590
gene id: 443218:AS9A_RS09590
uniprot id: F6ENF7
names: Similarity
messages: Belongs to the peptidase A31 family.

443218:AS9A RS16105
gene id: 443218:AS9A_RS16105
uniprot id: F6EPX8
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS15215
gene id: 443218:AS9A_RS15215
uniprot id: F6EMQ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

443218:AS9A RS20530
gene id: 443218:AS9A_RS20530
uniprot id: F6EL62
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

443218:AS9A RS17245
gene id: 443218:AS9A_RS17245
uniprot id: F6ES37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

443218:AS9A RS11865
gene id: 443218:AS9A_RS11865
uniprot id: F6EEW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

443218:AS9A RS04555
gene id: 443218:AS9A_RS04555
uniprot id: F6EN76
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS04175
gene id: 443218:AS9A_RS04175
uniprot id: F6EMA7
names: Similarity
messages: Belongs to the AccD/PCCB family.

443218:AS9A RS11740
gene id: 443218:AS9A_RS11740
uniprot id: F6EET5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

443218:AS9A RS04835
gene id: 443218:AS9A_RS04835
uniprot id: F6EPL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GcvT family.
messages: Cytoplasm

443218:AS9A RS08270
gene id: 443218:AS9A_RS08270
uniprot id: F6EKM7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

443218:AS9A RS05940
gene id: 443218:AS9A_RS05940
uniprot id: F6EEH9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

443218:AS9A RS06700
gene id: 443218:AS9A_RS06700
uniprot id: F6EGB3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

443218:AS9A RS03985
gene id: 443218:AS9A_RS03985
uniprot id: F6EM66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

443218:AS9A RS03900
gene id: 443218:AS9A_RS03900
uniprot id: F6EM47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

443218:AS9A RS12125
gene id: 443218:AS9A_RS12125
uniprot id: F6EFN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

443218:AS9A RS04705
gene id: 443218:AS9A_RS04705
uniprot id: F6EPJ1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

443218:AS9A RS17135
gene id: 443218:AS9A_RS17135
uniprot id: F6ERE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

443218:AS9A RS19040
gene id: 443218:AS9A_RS19040
uniprot id: F6EHQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS02550
gene id: 443218:AS9A_RS02550
uniprot id: F6EIQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

443218:AS9A RS16025
gene id: 443218:AS9A_RS16025
uniprot id: F6EPC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

443218:AS9A RS17495
gene id: 443218:AS9A_RS17495
uniprot id: F6ES86
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

443218:AS9A RS01275
gene id: 443218:AS9A_RS01275
uniprot id: F6EG19
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS19370
gene id: 443218:AS9A_RS19370
uniprot id: F6EIJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

443218:AS9A RS12560
gene id: 443218:AS9A_RS12560
uniprot id: F6EGK3
names: Similarity
messages: Belongs to the CdaR family.

443218:AS9A RS09015
gene id: 443218:AS9A_RS09015
uniprot id: F6EMF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

443218:AS9A RS15100
gene id: 443218:AS9A_RS15100
uniprot id: F6EMM8
names: Similarity
messages: Belongs to the UPF0749 family.

443218:AS9A RS06115
gene id: 443218:AS9A_RS06115
uniprot id: F6EEL5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

443218:AS9A RS13345
gene id: 443218:AS9A_RS13345
uniprot id: F6EIB6
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS06210
gene id: 443218:AS9A_RS06210
uniprot id: F6EFB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

443218:AS9A RS01345
gene id: 443218:AS9A_RS01345
uniprot id: F6EG32
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

443218:AS9A RS15260
gene id: 443218:AS9A_RS15260
uniprot id: F6EMR1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

443218:AS9A RS14960
gene id: 443218:AS9A_RS14960
uniprot id: F6EMJ9
names: Subcellular Location Annotation
messages: Membrane

443218:AS9A RS11925
gene id: 443218:AS9A_RS11925
uniprot id: F6EFJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

443218:AS9A RS04550
gene id: 443218:AS9A_RS04550
uniprot id: F6EN75
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.