438753:AZC RS22855
gene id: 438753:AZC_RS22855
uniprot id: A8HWP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

438753:AZC RS10630
gene id: 438753:AZC_RS10630
uniprot id: A8I6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

438753:AZC RS10435
gene id: 438753:AZC_RS10435
uniprot id: A8I3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS12910
gene id: 438753:AZC_RS12910
uniprot id: A8IAD8
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
messages: Involved in pyrimidine catabolism. May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.

438753:AZC RS03280
gene id: 438753:AZC_RS03280
uniprot id: A8IPL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

438753:AZC RS04130
gene id: 438753:AZC_RS04130
uniprot id: A8IQQ6
names: Subcellular Location Annotation
messages: Cell inner membrane

438753:AZC RS22760
gene id: 438753:AZC_RS22760
uniprot id: A8HWJ0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS07235
gene id: 438753:AZC_RS07235
uniprot id: A8I1P0
names: Similarity
messages: Belongs to the pyruvate kinase family.

438753:AZC RS10515
gene id: 438753:AZC_RS10515
uniprot id: A8I3J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS07335
gene id: 438753:AZC_RS07335
uniprot id: A8HWT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

438753:AZC RS13225
gene id: 438753:AZC_RS13225
uniprot id: A8IAT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

438753:AZC RS13265
gene id: 438753:AZC_RS13265
uniprot id: A8IAV3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

438753:AZC RS09680
gene id: 438753:AZC_RS09680
uniprot id: A8I2F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

438753:AZC RS15040
gene id: 438753:AZC_RS15040
uniprot id: A8IDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS05130
gene id: 438753:AZC_RS05130
uniprot id: A8HV21
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

438753:AZC RS14485
gene id: 438753:AZC_RS14485
uniprot id: A8I9K6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

438753:AZC RS15025
gene id: 438753:AZC_RS15025
uniprot id: A8IDB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS10270
gene id: 438753:AZC_RS10270
uniprot id: A8I352
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS21090
gene id: 438753:AZC_RS21090
uniprot id: A8HRY2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS02650
gene id: 438753:AZC_RS02650
uniprot id: A8IMB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

438753:AZC RS18590
gene id: 438753:AZC_RS18590
uniprot id: A8IFE5
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.

438753:AZC RS03915
gene id: 438753:AZC_RS03915
uniprot id: A8IQD2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily.
messages: Binds 2 Zn(2+) ions per subunit.

438753:AZC RS07775
gene id: 438753:AZC_RS07775
uniprot id: A8HXJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

438753:AZC RS15330
gene id: 438753:AZC_RS15330
uniprot id: A8IDN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

438753:AZC RS17175
gene id: 438753:AZC_RS17175
uniprot id: A8IHY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

438753:AZC RS21405
gene id: 438753:AZC_RS21405
uniprot id: A8HSE3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

438753:AZC RS05325
gene id: 438753:AZC_RS05325
uniprot id: A8HQI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

438753:AZC RS02665
gene id: 438753:AZC_RS02665
uniprot id: A8IMC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

438753:AZC RS05350
gene id: 438753:AZC_RS05350
uniprot id: A8HQL3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

438753:AZC RS18305
gene id: 438753:AZC_RS18305
uniprot id: A8IF02
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

438753:AZC RS20140
gene id: 438753:AZC_RS20140
uniprot id: P33982
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS17995
gene id: 438753:AZC_RS17995
uniprot id: A8IEJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

438753:AZC RS22420
gene id: 438753:AZC_RS22420
uniprot id: A8HVZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS02970
gene id: 438753:AZC_RS02970
uniprot id: A8IMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

438753:AZC RS04670
gene id: 438753:AZC_RS04670
uniprot id: A8HU60
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

438753:AZC RS00520
gene id: 438753:AZC_RS00520
uniprot id: A8IGL3
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

438753:AZC RS06020
gene id: 438753:AZC_RS06020
uniprot id: A8HRD6
names: Similarity
messages: Belongs to the GcvT family.

438753:AZC RS05770
gene id: 438753:AZC_RS05770
uniprot id: A8HR61
names: Similarity
messages: Belongs to the peptidase C40 family.

438753:AZC RS17305
gene id: 438753:AZC_RS17305
uniprot id: A8II50
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

438753:AZC RS01550
gene id: 438753:AZC_RS01550
uniprot id: A8IJH3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

438753:AZC RS11965
gene id: 438753:AZC_RS11965
uniprot id: A8I5R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

438753:AZC RS06440
gene id: 438753:AZC_RS06440
uniprot id: A8I0F4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

438753:AZC RS16050
gene id: 438753:AZC_RS16050
uniprot id: A8IBS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

438753:AZC RS08000
gene id: 438753:AZC_RS08000
uniprot id: A8HXX3
names: Function
names: Similarity
messages: Belongs to the amidase family.
messages: Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).

438753:AZC RS16460
gene id: 438753:AZC_RS16460
uniprot id: A8ICC9
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS18880
gene id: 438753:AZC_RS18880
uniprot id: A8IMV4
names: Similarity
messages: Belongs to the GppA/Ppx family.

438753:AZC RS17745
gene id: 438753:AZC_RS17745
uniprot id: P26485
names: Function
names: Similarity
messages: Could be a 3Fe-4S cluster-containing protein.
messages: To ferredoxins from P.putida and C.tartarivorum, ferredoxin I from A.vinelandii, ferredoxin II from D.desulfuricans.

438753:AZC RS19435
gene id: 438753:AZC_RS19435
uniprot id: A8INP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS02555
gene id: 438753:AZC_RS02555
uniprot id: A8IM77
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

438753:AZC RS02470
gene id: 438753:AZC_RS02470
uniprot id: A8IM48
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

438753:AZC RS12285
gene id: 438753:AZC_RS12285
uniprot id: A8I677
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

438753:AZC RS22015
gene id: 438753:AZC_RS22015
uniprot id: A8HV99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

438753:AZC RS23405
gene id: 438753:AZC_RS23405
uniprot id: A8HZC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

438753:AZC RS14435
gene id: 438753:AZC_RS14435
uniprot id: A8I9H9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS24125
gene id: 438753:AZC_RS24125
uniprot id: A8I264
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

438753:AZC RS23905
gene id: 438753:AZC_RS23905
uniprot id: A8I050
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

438753:AZC RS14090
gene id: 438753:AZC_RS14090
uniprot id: A8I8Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

438753:AZC RS13930
gene id: 438753:AZC_RS13930
uniprot id: A8I8Q9
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS21565
gene id: 438753:AZC_RS21565
uniprot id: A8HSN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

438753:AZC RS04680
gene id: 438753:AZC_RS04680
uniprot id: A8HU67
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS20435
gene id: 438753:AZC_RS20435
uniprot id: A8IL35
names: Subcellular Location Annotation
messages: Mitochondrion

438753:AZC RS13825
gene id: 438753:AZC_RS13825
uniprot id: A8I8K5
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS07920
gene id: 438753:AZC_RS07920
uniprot id: A8HXS5
names: Similarity
messages: Belongs to the peptidase C15 family.

438753:AZC RS04870
gene id: 438753:AZC_RS04870
uniprot id: A8HUI4
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

438753:AZC RS05035
gene id: 438753:AZC_RS05035
uniprot id: A8HUU2
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS16905
gene id: 438753:AZC_RS16905
uniprot id: A8IHI6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS17965
gene id: 438753:AZC_RS17965
uniprot id: A8IEI0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

438753:AZC RS13820
gene id: 438753:AZC_RS13820
uniprot id: A8I8K1
names: Similarity
messages: Belongs to the PrpF family.

438753:AZC RS19365
gene id: 438753:AZC_RS19365
uniprot id: A8INJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS12450
gene id: 438753:AZC_RS12450
uniprot id: A8I6G7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

438753:AZC RS20290
gene id: 438753:AZC_RS20290
uniprot id: A8IKV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

438753:AZC RS16470
gene id: 438753:AZC_RS16470
uniprot id: A8ICD4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS05190
gene id: 438753:AZC_RS05190
uniprot id: A8HQ04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

438753:AZC RS06705
gene id: 438753:AZC_RS06705
uniprot id: A8I0W8
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS15435
gene id: 438753:AZC_RS15435
uniprot id: A8IDT0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS23070
gene id: 438753:AZC_RS23070
uniprot id: A8HYU3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

438753:AZC RS19000
gene id: 438753:AZC_RS19000
uniprot id: A8IN11
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

438753:AZC RS13860
gene id: 438753:AZC_RS13860
uniprot id: A8I8M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS05455
gene id: 438753:AZC_RS05455
uniprot id: A8HQU9
names: Similarity
messages: Belongs to the PhzF family.

438753:AZC RS16915
gene id: 438753:AZC_RS16915
uniprot id: A8IHJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS18690
gene id: 438753:AZC_RS18690
uniprot id: A8IFL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

438753:AZC RS13210
gene id: 438753:AZC_RS13210
uniprot id: A8IAS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

438753:AZC RS22625
gene id: 438753:AZC_RS22625
uniprot id: A8HWC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

438753:AZC RS08365
gene id: 438753:AZC_RS08365
uniprot id: A8HYG7
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS08815
gene id: 438753:AZC_RS08815
uniprot id: A8I477
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS15220
gene id: 438753:AZC_RS15220
uniprot id: A8IDI4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS11870
gene id: 438753:AZC_RS11870
uniprot id: A8I5K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

438753:AZC RS20075
gene id: 438753:AZC_RS20075
uniprot id: A8IKI5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS13990
gene id: 438753:AZC_RS13990
uniprot id: A8I8U3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

438753:AZC RS04535
gene id: 438753:AZC_RS04535
uniprot id: A8HTX5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

438753:AZC RS08585
gene id: 438753:AZC_RS08585
uniprot id: A8I3U1
names: Similarity
messages: Belongs to the MipA/OmpV family.

438753:AZC RS01470
gene id: 438753:AZC_RS01470
uniprot id: A8IJD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

438753:AZC RS12785
gene id: 438753:AZC_RS12785
uniprot id: A8IA69
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS13245
gene id: 438753:AZC_RS13245
uniprot id: A8IAU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

438753:AZC RS10405
gene id: 438753:AZC_RS10405
uniprot id: A8I3C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

438753:AZC RS04725
gene id: 438753:AZC_RS04725
uniprot id: A8HU97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

438753:AZC RS04065
gene id: 438753:AZC_RS04065
uniprot id: A8IQL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

438753:AZC RS02755
gene id: 438753:AZC_RS02755
uniprot id: A8IMF7
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

438753:AZC RS11545
gene id: 438753:AZC_RS11545
uniprot id: A8I8A7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

438753:AZC RS25795
gene id: 438753:AZC_RS25795
uniprot id: A8IP96
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

438753:AZC RS12105
gene id: 438753:AZC_RS12105
uniprot id: A8I5Y7
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

438753:AZC RS09580
gene id: 438753:AZC_RS09580
uniprot id: A8I2B9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

438753:AZC RS13310
gene id: 438753:AZC_RS13310
uniprot id: A8IAX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

438753:AZC RS12290
gene id: 438753:AZC_RS12290
uniprot id: A8I679
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

438753:AZC RS05290
gene id: 438753:AZC_RS05290
uniprot id: A8HQE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

438753:AZC RS22310
gene id: 438753:AZC_RS22310
uniprot id: A8HVS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

438753:AZC RS02380
gene id: 438753:AZC_RS02380
uniprot id: A8IM21
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS10595
gene id: 438753:AZC_RS10595
uniprot id: A8I6U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS20785
gene id: 438753:AZC_RS20785
uniprot id: A8ILM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

438753:AZC RS07720
gene id: 438753:AZC_RS07720
uniprot id: A8HXG9
names: Similarity
messages: Belongs to the glutamate synthase family.

438753:AZC RS17880
gene id: 438753:AZC_RS17880
uniprot id: A8IED4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

438753:AZC RS19380
gene id: 438753:AZC_RS19380
uniprot id: A8INK9
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS21890
gene id: 438753:AZC_RS21890
uniprot id: A8HT80
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

438753:AZC RS23080
gene id: 438753:AZC_RS23080
uniprot id: A8HYU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

438753:AZC RS18700
gene id: 438753:AZC_RS18700
uniprot id: A8IFL9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS22870
gene id: 438753:AZC_RS22870
uniprot id: A8HWQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

438753:AZC RS08345
gene id: 438753:AZC_RS08345
uniprot id: A8HYF4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

438753:AZC RS22475
gene id: 438753:AZC_RS22475
uniprot id: A8HW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

438753:AZC RS10150
gene id: 438753:AZC_RS10150
uniprot id: A8I2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS14970
gene id: 438753:AZC_RS14970
uniprot id: A8ID91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

438753:AZC RS07760
gene id: 438753:AZC_RS07760
uniprot id: A8HXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

438753:AZC RS03285
gene id: 438753:AZC_RS03285
uniprot id: A8IPL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

438753:AZC RS03265
gene id: 438753:AZC_RS03265
uniprot id: A8IPK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

438753:AZC RS04075
gene id: 438753:AZC_RS04075
uniprot id: A8IQM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

438753:AZC RS06460
gene id: 438753:AZC_RS06460
uniprot id: A8I0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

438753:AZC RS03445
gene id: 438753:AZC_RS03445
uniprot id: A8IPQ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS14700
gene id: 438753:AZC_RS14700
uniprot id: A8I9X0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

438753:AZC RS10940
gene id: 438753:AZC_RS10940
uniprot id: A8I7F0
names: Similarity
messages: Belongs to the PrpD family.

438753:AZC RS23300
gene id: 438753:AZC_RS23300
uniprot id: A8HZ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

438753:AZC RS06265
gene id: 438753:AZC_RS06265
uniprot id: A8HRN4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

438753:AZC RS20570
gene id: 438753:AZC_RS20570
uniprot id: A8ILB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

438753:AZC RS10275
gene id: 438753:AZC_RS10275
uniprot id: A8I355
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS21265
gene id: 438753:AZC_RS21265
uniprot id: A8HS67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

438753:AZC RS06955
gene id: 438753:AZC_RS06955
uniprot id: A8I1A3
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

438753:AZC RS22535
gene id: 438753:AZC_RS22535
uniprot id: A8HW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS23175
gene id: 438753:AZC_RS23175
uniprot id: A8HZ05
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS14565
gene id: 438753:AZC_RS14565
uniprot id: A8I9Q2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

438753:AZC RS22720
gene id: 438753:AZC_RS22720
uniprot id: A8HWI2
names: Similarity
messages: Belongs to the peptidase M29 family.

438753:AZC RS13890
gene id: 438753:AZC_RS13890
uniprot id: A8I8N7
names: Similarity
messages: Belongs to the DapA family.

438753:AZC RS06385
gene id: 438753:AZC_RS06385
uniprot id: A8I0C3
names: Similarity
messages: Belongs to the PhzF family.

438753:AZC RS09065
gene id: 438753:AZC_RS09065
uniprot id: A8I4M5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

438753:AZC RS03100
gene id: 438753:AZC_RS03100
uniprot id: A8IPE7
names: Similarity
messages: Belongs to the HypE family.

438753:AZC RS01695
gene id: 438753:AZC_RS01695
uniprot id: A8IJN5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

438753:AZC RS01320
gene id: 438753:AZC_RS01320
uniprot id: A8IJ73
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

438753:AZC RS22575
gene id: 438753:AZC_RS22575
uniprot id: A8HW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS20440
gene id: 438753:AZC_RS20440
uniprot id: A8IL36
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

438753:AZC RS08705
gene id: 438753:AZC_RS08705
uniprot id: A8I410
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

438753:AZC RS09915
gene id: 438753:AZC_RS09915
uniprot id: A8I2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

438753:AZC RS04125
gene id: 438753:AZC_RS04125
uniprot id: A8IQQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS11505
gene id: 438753:AZC_RS11505
uniprot id: A8I883
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

438753:AZC RS11770
gene id: 438753:AZC_RS11770
uniprot id: A8I5G4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS10475
gene id: 438753:AZC_RS10475
uniprot id: A8I3G6
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS13215
gene id: 438753:AZC_RS13215
uniprot id: A8HTW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

438753:AZC RS05675
gene id: 438753:AZC_RS05675
uniprot id: A8HR27
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS19315
gene id: 438753:AZC_RS19315
uniprot id: A8ING6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

438753:AZC RS13145
gene id: 438753:AZC_RS13145
uniprot id: A8IAQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

438753:AZC RS00955
gene id: 438753:AZC_RS00955
uniprot id: A8IH90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

438753:AZC RS09070
gene id: 438753:AZC_RS09070
uniprot id: A8I4M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

438753:AZC RS21630
gene id: 438753:AZC_RS21630
uniprot id: A8HST0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

438753:AZC RS08695
gene id: 438753:AZC_RS08695
uniprot id: A8I404
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

438753:AZC RS17970
gene id: 438753:AZC_RS17970
uniprot id: A8IEI3
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

438753:AZC RS02865
gene id: 438753:AZC_RS02865
uniprot id: A8IMJ5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

438753:AZC RS17765
gene id: 438753:AZC_RS17765
uniprot id: A8IIV1
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

438753:AZC RS10765
gene id: 438753:AZC_RS10765
uniprot id: A8I749
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS03885
gene id: 438753:AZC_RS03885
uniprot id: A8IQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS04760
gene id: 438753:AZC_RS04760
uniprot id: A8HUB9
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.

438753:AZC RS19080
gene id: 438753:AZC_RS19080
uniprot id: A8IN54
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

438753:AZC RS00735
gene id: 438753:AZC_RS00735
uniprot id: A8IGX4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

438753:AZC RS08410
gene id: 438753:AZC_RS08410
uniprot id: A8HYI7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

438753:AZC RS01975
gene id: 438753:AZC_RS01975
uniprot id: A8IK13
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Multidrug efflux pump.

438753:AZC RS12955
gene id: 438753:AZC_RS12955
uniprot id: A8IAG1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS07255
gene id: 438753:AZC_RS07255
uniprot id: A8I1Q4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS17685
gene id: 438753:AZC_RS17685
uniprot id: A8IIQ9
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

438753:AZC RS05530
gene id: 438753:AZC_RS05530
uniprot id: A8HQZ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS13620
gene id: 438753:AZC_RS13620
uniprot id: A8IBA3
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS07995
gene id: 438753:AZC_RS07995
uniprot id: A8HXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS15870
gene id: 438753:AZC_RS15870
uniprot id: A8IBI6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS07990
gene id: 438753:AZC_RS07990
uniprot id: A8HXW7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

438753:AZC RS07555
gene id: 438753:AZC_RS07555
uniprot id: A8HX69
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

438753:AZC RS04490
gene id: 438753:AZC_RS04490
uniprot id: A8HTV5
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS09170
gene id: 438753:AZC_RS09170
uniprot id: A8I4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

438753:AZC RS02205
gene id: 438753:AZC_RS02205
uniprot id: A8ILW5
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS24010
gene id: 438753:AZC_RS24010
uniprot id: A8I206
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS06765
gene id: 438753:AZC_RS06765
uniprot id: A8I0Z8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS01835
gene id: 438753:AZC_RS01835
uniprot id: A8IJU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

438753:AZC RS04555
gene id: 438753:AZC_RS04555
uniprot id: A8HTY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

438753:AZC RS05140
gene id: 438753:AZC_RS05140
uniprot id: A8HV25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

438753:AZC RS18095
gene id: 438753:AZC_RS18095
uniprot id: A8IEP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

438753:AZC RS17180
gene id: 438753:AZC_RS17180
uniprot id: A8IHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

438753:AZC RS13570
gene id: 438753:AZC_RS13570
uniprot id: A8IB82
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS03940
gene id: 438753:AZC_RS03940
uniprot id: A8IQE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS15975
gene id: 438753:AZC_RS15975
uniprot id: A8IBN6
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS13865
gene id: 438753:AZC_RS13865
uniprot id: A8I8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS23055
gene id: 438753:AZC_RS23055
uniprot id: A8HYT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

438753:AZC RS03335
gene id: 438753:AZC_RS03335
uniprot id: A8IPM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

438753:AZC RS17225
gene id: 438753:AZC_RS17225
uniprot id: A8II07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS18230
gene id: 438753:AZC_RS18230
uniprot id: A8IEW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

438753:AZC RS22260
gene id: 438753:AZC_RS22260
uniprot id: A8HVP5
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

438753:AZC RS02880
gene id: 438753:AZC_RS02880
uniprot id: A8IMK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

438753:AZC RS00515
gene id: 438753:AZC_RS00515
uniprot id: A8IGL1
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

438753:AZC RS04885
gene id: 438753:AZC_RS04885
uniprot id: A8HUJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS12295
gene id: 438753:AZC_RS12295
uniprot id: A8I682
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

438753:AZC RS09265
gene id: 438753:AZC_RS09265
uniprot id: A8I4Y2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

438753:AZC RS15465
gene id: 438753:AZC_RS15465
uniprot id: A8IDU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS03710
gene id: 438753:AZC_RS03710
uniprot id: A8IQ06
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

438753:AZC RS08945
gene id: 438753:AZC_RS08945
uniprot id: A8I4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecG subfamily.
messages: Cell inner membrane
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

438753:AZC RS05895
gene id: 438753:AZC_RS05895
uniprot id: A8HR97
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

438753:AZC RS18680
gene id: 438753:AZC_RS18680
uniprot id: A8IFK5
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

438753:AZC RS05825
gene id: 438753:AZC_RS05825
uniprot id: A8HR76
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

438753:AZC RS07400
gene id: 438753:AZC_RS07400
uniprot id: A8HWX3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS23375
gene id: 438753:AZC_RS23375
uniprot id: A8HZA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

438753:AZC RS13950
gene id: 438753:AZC_RS13950
uniprot id: A8I8S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS19290
gene id: 438753:AZC_RS19290
uniprot id: A8INF2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

438753:AZC RS06085
gene id: 438753:AZC_RS06085
uniprot id: A8HRG2
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS15455
gene id: 438753:AZC_RS15455
uniprot id: A8IDU0
names: Similarity
messages: Belongs to the peptidase S58 family.

438753:AZC RS09870
gene id: 438753:AZC_RS09870
uniprot id: A8I2N0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS10655
gene id: 438753:AZC_RS10655
uniprot id: A8I6Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS10875
gene id: 438753:AZC_RS10875
uniprot id: A8I7B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

438753:AZC RS23950
gene id: 438753:AZC_RS23950
uniprot id: A8I1W6
names: Similarity
messages: Belongs to the SDHAF4 family.

438753:AZC RS17610
gene id: 438753:AZC_RS17610
uniprot id: A8IIL9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

438753:AZC RS23180
gene id: 438753:AZC_RS23180
uniprot id: A8HZ07
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

438753:AZC RS20820
gene id: 438753:AZC_RS20820
uniprot id: A8ILP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

438753:AZC RS17565
gene id: 438753:AZC_RS17565
uniprot id: A8IIJ5
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

438753:AZC RS08335
gene id: 438753:AZC_RS08335
uniprot id: A8HYF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

438753:AZC RS04195
gene id: 438753:AZC_RS04195
uniprot id: A8HTC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell inner membrane

438753:AZC RS11520
gene id: 438753:AZC_RS11520
uniprot id: A8I892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS14050
gene id: 438753:AZC_RS14050
uniprot id: A8I8X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS21790
gene id: 438753:AZC_RS21790
uniprot id: A8HT21
names: Similarity
messages: Belongs to the GcvT family.

438753:AZC RS09715
gene id: 438753:AZC_RS09715
uniprot id: A8I2H0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS13510
gene id: 438753:AZC_RS13510
uniprot id: A8IB59
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

438753:AZC RS04585
gene id: 438753:AZC_RS04585
uniprot id: A8HU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

438753:AZC RS06510
gene id: 438753:AZC_RS06510
uniprot id: A8I0J5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

438753:AZC RS04810
gene id: 438753:AZC_RS04810
uniprot id: A8HUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

438753:AZC RS12670
gene id: 438753:AZC_RS12670
uniprot id: A8IA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS21055
gene id: 438753:AZC_RS21055
uniprot id: A8HRW5
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS21130
gene id: 438753:AZC_RS21130
uniprot id: A8HS00
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS07770
gene id: 438753:AZC_RS07770
uniprot id: A8HXJ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

438753:AZC RS21905
gene id: 438753:AZC_RS21905
uniprot id: A8HV53
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

438753:AZC RS12415
gene id: 438753:AZC_RS12415
uniprot id: A8I6E9
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS19580
gene id: 438753:AZC_RS19580
uniprot id: A8INX5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS03705
gene id: 438753:AZC_RS03705
uniprot id: A8IQ03
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

438753:AZC RS18675
gene id: 438753:AZC_RS18675
uniprot id: A8IFK1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

438753:AZC RS22930
gene id: 438753:AZC_RS22930
uniprot id: A8HYK3
names: Similarity
messages: Belongs to the UPF0102 family.

438753:AZC RS14985
gene id: 438753:AZC_RS14985
uniprot id: A8IDA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

438753:AZC RS17000
gene id: 438753:AZC_RS17000
uniprot id: A8IHN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

438753:AZC RS22120
gene id: 438753:AZC_RS22120
uniprot id: A8HVG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

438753:AZC RS06340
gene id: 438753:AZC_RS06340
uniprot id: A8I0A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

438753:AZC RS22605
gene id: 438753:AZC_RS22605
uniprot id: A8HWB2
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS07915
gene id: 438753:AZC_RS07915
uniprot id: A8HXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

438753:AZC RS23770
gene id: 438753:AZC_RS23770
uniprot id: A8HZX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

438753:AZC RS19945
gene id: 438753:AZC_RS19945
uniprot id: A8IKC0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS19555
gene id: 438753:AZC_RS19555
uniprot id: A8INW5
names: Function
names: Similarity
messages: Belongs to the nitrile hydratase subunit beta family.
messages: NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.

438753:AZC RS22810
gene id: 438753:AZC_RS22810
uniprot id: A8HWM0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

438753:AZC RS10390
gene id: 438753:AZC_RS10390
uniprot id: A8I3B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

438753:AZC RS13175
gene id: 438753:AZC_RS13175
uniprot id: A8IAR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

438753:AZC RS08280
gene id: 438753:AZC_RS08280
uniprot id: A8HYB7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

438753:AZC RS00630
gene id: 438753:AZC_RS00630
uniprot id: A8IGS2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS11425
gene id: 438753:AZC_RS11425
uniprot id: A8I839
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

438753:AZC RS16005
gene id: 438753:AZC_RS16005
uniprot id: A8IBP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

438753:AZC RS00860
gene id: 438753:AZC_RS00860
uniprot id: A8IH44
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

438753:AZC RS09785
gene id: 438753:AZC_RS09785
uniprot id: A8I2J8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS20835
gene id: 438753:AZC_RS20835
uniprot id: A8ILP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

438753:AZC RS13720
gene id: 438753:AZC_RS13720
uniprot id: A8I8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS08800
gene id: 438753:AZC_RS08800
uniprot id: A8I468
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

438753:AZC RS25545
gene id: 438753:AZC_RS25545
uniprot id: A8ID85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

438753:AZC RS22405
gene id: 438753:AZC_RS22405
uniprot id: A8HVY1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

438753:AZC RS23830
gene id: 438753:AZC_RS23830
uniprot id: A8I010
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

438753:AZC RS12025
gene id: 438753:AZC_RS12025
uniprot id: A8I5U7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

438753:AZC RS15645
gene id: 438753:AZC_RS15645
uniprot id: A8IE36
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS20350
gene id: 438753:AZC_RS20350
uniprot id: A8IKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

438753:AZC RS01325
gene id: 438753:AZC_RS01325
uniprot id: A8IJ75
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

438753:AZC RS17750
gene id: 438753:AZC_RS17750
uniprot id: P26486
names: Similarity
messages: Belongs to the UPF0437 family.

438753:AZC RS22005
gene id: 438753:AZC_RS22005
uniprot id: A8HV93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

438753:AZC RS07905
gene id: 438753:AZC_RS07905
uniprot id: A8HXR5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

438753:AZC RS02960
gene id: 438753:AZC_RS02960
uniprot id: A8IMN2
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS20770
gene id: 438753:AZC_RS20770
uniprot id: A8ILL4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

438753:AZC RS23695
gene id: 438753:AZC_RS23695
uniprot id: A8HZU0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

438753:AZC RS07590
gene id: 438753:AZC_RS07590
uniprot id: A8HX91
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS18005
gene id: 438753:AZC_RS18005
uniprot id: A8IEK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

438753:AZC RS10505
gene id: 438753:AZC_RS10505
uniprot id: A8I3I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS13100
gene id: 438753:AZC_RS13100
uniprot id: A8IAP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

438753:AZC RS05470
gene id: 438753:AZC_RS05470
uniprot id: A8HQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS22355
gene id: 438753:AZC_RS22355
uniprot id: A8HVU8
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS13675
gene id: 438753:AZC_RS13675
uniprot id: A8IBC8
names: Similarity
messages: Belongs to the IlvD/Edd family.

438753:AZC RS02375
gene id: 438753:AZC_RS02375
uniprot id: A8IM19
names: Similarity
messages: Belongs to the TPP enzyme family.

438753:AZC RS21805
gene id: 438753:AZC_RS21805
uniprot id: A8HT29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

438753:AZC RS14355
gene id: 438753:AZC_RS14355
uniprot id: A8I9D4
names: Similarity
messages: Belongs to the hyi family.

438753:AZC RS07750
gene id: 438753:AZC_RS07750
uniprot id: A8HXI5
names: Similarity
messages: Belongs to the LOG family.

438753:AZC RS12865
gene id: 438753:AZC_RS12865
uniprot id: A8IAB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS19350
gene id: 438753:AZC_RS19350
uniprot id: A8INI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

438753:AZC RS09780
gene id: 438753:AZC_RS09780
uniprot id: A8I2J6
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS18705
gene id: 438753:AZC_RS18705
uniprot id: A8IFM0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

438753:AZC RS13530
gene id: 438753:AZC_RS13530
uniprot id: A8IB67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS13795
gene id: 438753:AZC_RS13795
uniprot id: A8I8I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS08785
gene id: 438753:AZC_RS08785
uniprot id: A8I460
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

438753:AZC RS21660
gene id: 438753:AZC_RS21660
uniprot id: A8HSU8
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS02090
gene id: 438753:AZC_RS02090
uniprot id: A8ILT0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

438753:AZC RS06275
gene id: 438753:AZC_RS06275
uniprot id: A8I066
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

438753:AZC RS13315
gene id: 438753:AZC_RS13315
uniprot id: A8IAX5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

438753:AZC RS09525
gene id: 438753:AZC_RS09525
uniprot id: A8I299
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS16435
gene id: 438753:AZC_RS16435
uniprot id: A8ICB7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

438753:AZC RS00900
gene id: 438753:AZC_RS00900
uniprot id: A8IH65
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

438753:AZC RS07465
gene id: 438753:AZC_RS07465
uniprot id: A8HX12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS03035
gene id: 438753:AZC_RS03035
uniprot id: A8IMR8
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

438753:AZC RS07675
gene id: 438753:AZC_RS07675
uniprot id: A8HXE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

438753:AZC RS10905
gene id: 438753:AZC_RS10905
uniprot id: A8I7C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

438753:AZC RS08650
gene id: 438753:AZC_RS08650
uniprot id: A8I3Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

438753:AZC RS24160
gene id: 438753:AZC_RS24160
uniprot id: A8I277
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rho family.
messages: Cell inner membrane
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS10995
gene id: 438753:AZC_RS10995
uniprot id: A8I7I4
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

438753:AZC RS21995
gene id: 438753:AZC_RS21995
uniprot id: A8HV88
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

438753:AZC RS23275
gene id: 438753:AZC_RS23275
uniprot id: A8HZ57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

438753:AZC RS07280
gene id: 438753:AZC_RS07280
uniprot id: A8I1S2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

438753:AZC RS07350
gene id: 438753:AZC_RS07350
uniprot id: A8HWU6
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS06970
gene id: 438753:AZC_RS06970
uniprot id: A8I1B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS08525
gene id: 438753:AZC_RS08525
uniprot id: A8I3Q5
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

438753:AZC RS21735
gene id: 438753:AZC_RS21735
uniprot id: A8HSY9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

438753:AZC RS02830
gene id: 438753:AZC_RS02830
uniprot id: A8IMI1
names: Caution
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS04665
gene id: 438753:AZC_RS04665
uniprot id: A8HU57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

438753:AZC RS08355
gene id: 438753:AZC_RS08355
uniprot id: A8HYG0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

438753:AZC RS08725
gene id: 438753:AZC_RS08725
uniprot id: A8I421
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

438753:AZC RS09645
gene id: 438753:AZC_RS09645
uniprot id: A8I2E5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

438753:AZC RS14535
gene id: 438753:AZC_RS14535
uniprot id: A8I9N5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

438753:AZC RS17760
gene id: 438753:AZC_RS17760
uniprot id: A8IIV0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

438753:AZC RS04880
gene id: 438753:AZC_RS04880
uniprot id: A8HUI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

438753:AZC RS16300
gene id: 438753:AZC_RS16300
uniprot id: A8IC47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

438753:AZC RS23350
gene id: 438753:AZC_RS23350
uniprot id: A8HZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

438753:AZC RS21795
gene id: 438753:AZC_RS21795
uniprot id: A8HT23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

438753:AZC RS12760
gene id: 438753:AZC_RS12760
uniprot id: A8IA55
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

438753:AZC RS01700
gene id: 438753:AZC_RS01700
uniprot id: A8IJN7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

438753:AZC RS10105
gene id: 438753:AZC_RS10105
uniprot id: A8I2X1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS16360
gene id: 438753:AZC_RS16360
uniprot id: A8IC78
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

438753:AZC RS12385
gene id: 438753:AZC_RS12385
uniprot id: A8I6D2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

438753:AZC RS09505
gene id: 438753:AZC_RS09505
uniprot id: A8I295
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

438753:AZC RS11435
gene id: 438753:AZC_RS11435
uniprot id: A8I845
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

438753:AZC RS01070
gene id: 438753:AZC_RS01070
uniprot id: A8IIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

438753:AZC RS16500
gene id: 438753:AZC_RS16500
uniprot id: A8ICF0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS23035
gene id: 438753:AZC_RS23035
uniprot id: A8HYS0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

438753:AZC RS09845
gene id: 438753:AZC_RS09845
uniprot id: A8I2M2
names: Similarity
messages: Belongs to the MQO family.

438753:AZC RS13845
gene id: 438753:AZC_RS13845
uniprot id: A8I8L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

438753:AZC RS16225
gene id: 438753:AZC_RS16225
uniprot id: A8IC08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

438753:AZC RS00890
gene id: 438753:AZC_RS00890
uniprot id: A8IH60
names: Similarity
messages: Belongs to the DapA family.

438753:AZC RS07025
gene id: 438753:AZC_RS07025
uniprot id: A8I1E3
names: Similarity
messages: Belongs to the asparagine synthetase family.

438753:AZC RS01925
gene id: 438753:AZC_RS01925
uniprot id: A8IJY4
names: Similarity
messages: Belongs to the SCO1/2 family.

438753:AZC RS03025
gene id: 438753:AZC_RS03025
uniprot id: A8IMR4
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

438753:AZC RS21960
gene id: 438753:AZC_RS21960
uniprot id: A8HV67
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS00665
gene id: 438753:AZC_RS00665
uniprot id: A8IGU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS23390
gene id: 438753:AZC_RS23390
uniprot id: A8HZB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

438753:AZC RS21695
gene id: 438753:AZC_RS21695
uniprot id: A8HSW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

438753:AZC RS16995
gene id: 438753:AZC_RS16995
uniprot id: A8IHN1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

438753:AZC RS03030
gene id: 438753:AZC_RS03030
uniprot id: A8IMR5
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

438753:AZC RS23200
gene id: 438753:AZC_RS23200
uniprot id: A8HZ17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. FixP subunit is required for transferring electrons from donor cytochrome c via its heme groups to FixO subunit. From there, electrons are shuttled to the catalytic binuclear center of FixN subunit where oxygen reduction takes place. The complex also functions as a proton pump (By similarity).
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase at least composed of FixN, FixO, FixQ and FixP.

438753:AZC RS20240
gene id: 438753:AZC_RS20240
uniprot id: A8IKS3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

438753:AZC RS13775
gene id: 438753:AZC_RS13775
uniprot id: A8I8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS17910
gene id: 438753:AZC_RS17910
uniprot id: A8IEF2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

438753:AZC RS20130
gene id: 438753:AZC_RS20130
uniprot id: A8IKL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

438753:AZC RS17035
gene id: 438753:AZC_RS17035
uniprot id: A8IHQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

438753:AZC RS08020
gene id: 438753:AZC_RS08020
uniprot id: A8HXY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS12630
gene id: 438753:AZC_RS12630
uniprot id: A8I9Y5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

438753:AZC RS07450
gene id: 438753:AZC_RS07450
uniprot id: A8HX03
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS08550
gene id: 438753:AZC_RS08550
uniprot id: A8I3S0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS10860
gene id: 438753:AZC_RS10860
uniprot id: A8I7A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

438753:AZC RS09490
gene id: 438753:AZC_RS09490
uniprot id: A8I290
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

438753:AZC RS01260
gene id: 438753:AZC_RS01260
uniprot id: A8IJ45
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

438753:AZC RS08540
gene id: 438753:AZC_RS08540
uniprot id: A8I3R4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

438753:AZC RS22480
gene id: 438753:AZC_RS22480
uniprot id: A8HW33
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS19065
gene id: 438753:AZC_RS19065
uniprot id: A8IN45
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS07365
gene id: 438753:AZC_RS07365
uniprot id: A8HWV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

438753:AZC RS08660
gene id: 438753:AZC_RS08660
uniprot id: A8I3Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

438753:AZC RS18010
gene id: 438753:AZC_RS18010
uniprot id: A8IEK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

438753:AZC RS12815
gene id: 438753:AZC_RS12815
uniprot id: A8IA85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS22795
gene id: 438753:AZC_RS22795
uniprot id: A8HWL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

438753:AZC RS12935
gene id: 438753:AZC_RS12935
uniprot id: A8IAF2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

438753:AZC RS09000
gene id: 438753:AZC_RS09000
uniprot id: A8I4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

438753:AZC RS02800
gene id: 438753:AZC_RS02800
uniprot id: A8IMH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

438753:AZC RS00030
gene id: 438753:AZC_RS00030
uniprot id: A8IFZ2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

438753:AZC RS01335
gene id: 438753:AZC_RS01335
uniprot id: A8IJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

438753:AZC RS03655
gene id: 438753:AZC_RS03655
uniprot id: A8IPY1
names: Similarity
messages: Belongs to the thioredoxin family.

438753:AZC RS20135
gene id: 438753:AZC_RS20135
uniprot id: P33984
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes.

438753:AZC RS20580
gene id: 438753:AZC_RS20580
uniprot id: A8ILB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

438753:AZC RS10075
gene id: 438753:AZC_RS10075
uniprot id: A8I2V8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS05045
gene id: 438753:AZC_RS05045
uniprot id: A8HUV1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

438753:AZC RS21820
gene id: 438753:AZC_RS21820
uniprot id: A8HT36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

438753:AZC RS12335
gene id: 438753:AZC_RS12335
uniprot id: A8I6A3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

438753:AZC RS06455
gene id: 438753:AZC_RS06455
uniprot id: A8I0G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

438753:AZC RS03330
gene id: 438753:AZC_RS03330
uniprot id: A8IPM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

438753:AZC RS23810
gene id: 438753:AZC_RS23810
uniprot id: A8HZZ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

438753:AZC RS14350
gene id: 438753:AZC_RS14350
uniprot id: A8I9D2
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

438753:AZC RS11890
gene id: 438753:AZC_RS11890
uniprot id: A8I5L9
names: Similarity
messages: Belongs to the UPF0174 family.

438753:AZC RS02160
gene id: 438753:AZC_RS02160
uniprot id: A8ILV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

438753:AZC RS22825
gene id: 438753:AZC_RS22825
uniprot id: A8HWN0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

438753:AZC RS15700
gene id: 438753:AZC_RS15700
uniprot id: A8IE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS21150
gene id: 438753:AZC_RS21150
uniprot id: A8HS09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

438753:AZC RS03505
gene id: 438753:AZC_RS03505
uniprot id: A8IPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS15510
gene id: 438753:AZC_RS15510
uniprot id: A8IDW4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS21115
gene id: 438753:AZC_RS21115
uniprot id: A8HRZ3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

438753:AZC RS14525
gene id: 438753:AZC_RS14525
uniprot id: A8I9M9
names: Subcellular Location Annotation
messages: Periplasm

438753:AZC RS15270
gene id: 438753:AZC_RS15270
uniprot id: A8IDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

438753:AZC RS22540
gene id: 438753:AZC_RS22540
uniprot id: A8HW75
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS09450
gene id: 438753:AZC_RS09450
uniprot id: A8I562
names: Similarity
messages: Belongs to the universal stress protein A family.

438753:AZC RS07855
gene id: 438753:AZC_RS07855
uniprot id: A8HXP0
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS10370
gene id: 438753:AZC_RS10370
uniprot id: A8I3A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

438753:AZC RS01730
gene id: 438753:AZC_RS01730
uniprot id: A8IJQ3
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS16255
gene id: 438753:AZC_RS16255
uniprot id: A8IC24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

438753:AZC RS04045
gene id: 438753:AZC_RS04045
uniprot id: A8IQK2
names: Similarity
messages: Belongs to the peptidase M20A family.

438753:AZC RS15905
gene id: 438753:AZC_RS15905
uniprot id: Q04849
names: Function
messages: Member of the two-component regulatory system NtrY/NtrX involved in the activation of nitrogen assimilatory genes such as GlnA. NtrX is probably phosphorylated by NtrY and interacts with sigma-54.

438753:AZC RS18275
gene id: 438753:AZC_RS18275
uniprot id: A8IEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

438753:AZC RS20805
gene id: 438753:AZC_RS20805
uniprot id: A8ILN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

438753:AZC RS16245
gene id: 438753:AZC_RS16245
uniprot id: A8IC19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

438753:AZC RS20490
gene id: 438753:AZC_RS20490
uniprot id: A8IL64
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS06890
gene id: 438753:AZC_RS06890
uniprot id: A8I165
names: Similarity
messages: Belongs to the SCO1/2 family.

438753:AZC RS23470
gene id: 438753:AZC_RS23470
uniprot id: A8HZG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

438753:AZC RS20600
gene id: 438753:AZC_RS20600
uniprot id: A8ILC6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

438753:AZC RS03745
gene id: 438753:AZC_RS03745
uniprot id: A8IQ23
names: Similarity
messages: Belongs to the DSD1 family.

438753:AZC RS05485
gene id: 438753:AZC_RS05485
uniprot id: A8HQX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

438753:AZC RS20295
gene id: 438753:AZC_RS20295
uniprot id: A8IKV6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

438753:AZC RS19985
gene id: 438753:AZC_RS19985
uniprot id: A8IKD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS08760
gene id: 438753:AZC_RS08760
uniprot id: A8I444
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS14730
gene id: 438753:AZC_RS14730
uniprot id: A8ICV3
names: Similarity
messages: Belongs to the DprA/Smf family.

438753:AZC RS07075
gene id: 438753:AZC_RS07075
uniprot id: A8I1G8
names: Similarity
messages: Belongs to the FMO family.

438753:AZC RS06330
gene id: 438753:AZC_RS06330
uniprot id: A8I095
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS15865
gene id: 438753:AZC_RS15865
uniprot id: A8IBI4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

438753:AZC RS13680
gene id: 438753:AZC_RS13680
uniprot id: A8I8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS07265
gene id: 438753:AZC_RS07265
uniprot id: A8I1R1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

438753:AZC RS03075
gene id: 438753:AZC_RS03075
uniprot id: A8IMT6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

438753:AZC RS04150
gene id: 438753:AZC_RS04150
uniprot id: A8HT96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS09060
gene id: 438753:AZC_RS09060
uniprot id: A8I4M2
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

438753:AZC RS01135
gene id: 438753:AZC_RS01135
uniprot id: A8IIZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

438753:AZC RS20680
gene id: 438753:AZC_RS20680
uniprot id: A8ILH0
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

438753:AZC RS03310
gene id: 438753:AZC_RS03310
uniprot id: A8IPL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

438753:AZC RS04540
gene id: 438753:AZC_RS04540
uniprot id: A8HTX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

438753:AZC RS13105
gene id: 438753:AZC_RS13105
uniprot id: A8IAP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

438753:AZC RS08110
gene id: 438753:AZC_RS08110
uniprot id: A8HY19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

438753:AZC RS18105
gene id: 438753:AZC_RS18105
uniprot id: A8IEQ0
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

438753:AZC RS05815
gene id: 438753:AZC_RS05815
uniprot id: A8HR72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

438753:AZC RS03715
gene id: 438753:AZC_RS03715
uniprot id: A8IQ08
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS08830
gene id: 438753:AZC_RS08830
uniprot id: A8I485
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

438753:AZC RS17350
gene id: 438753:AZC_RS17350
uniprot id: A8II75
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS11980
gene id: 438753:AZC_RS11980
uniprot id: A8I5S4
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS15410
gene id: 438753:AZC_RS15410
uniprot id: A8IDR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

438753:AZC RS09855
gene id: 438753:AZC_RS09855
uniprot id: A8I2M5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

438753:AZC RS21870
gene id: 438753:AZC_RS21870
uniprot id: A8HT67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

438753:AZC RS05185
gene id: 438753:AZC_RS05185
uniprot id: A8HV52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

438753:AZC RS13030
gene id: 438753:AZC_RS13030
uniprot id: A8IAK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

438753:AZC RS12860
gene id: 438753:AZC_RS12860
uniprot id: A8IAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS13400
gene id: 438753:AZC_RS13400
uniprot id: A8IB09
names: Similarity
messages: Belongs to the VgrG protein family.

438753:AZC RS03095
gene id: 438753:AZC_RS03095
uniprot id: A8IMU6
names: Similarity
messages: Belongs to the HypD family.

438753:AZC RS20795
gene id: 438753:AZC_RS20795
uniprot id: A8ILM7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

438753:AZC RS23840
gene id: 438753:AZC_RS23840
uniprot id: P26489
names: Activity Regulation
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 heme group per subunit.
messages: Cell inner membrane
messages: Putative oxygen sensor; modulates the activity of FixJ, a transcriptional activator of nitrogen fixation fixK gene. FixL probably acts as a kinase that phosphorylates FixJ.
messages: The heme moiety regulates the kinase activity.

438753:AZC RS21855
gene id: 438753:AZC_RS21855
uniprot id: A8HT58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

438753:AZC RS07810
gene id: 438753:AZC_RS07810
uniprot id: A8HXL5
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS02710
gene id: 438753:AZC_RS02710
uniprot id: A8IME0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS03575
gene id: 438753:AZC_RS03575
uniprot id: A8IPU9
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

438753:AZC RS15860
gene id: 438753:AZC_RS15860
uniprot id: A8IBI2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

438753:AZC RS21400
gene id: 438753:AZC_RS21400
uniprot id: A8HSE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

438753:AZC RS09705
gene id: 438753:AZC_RS09705
uniprot id: A8I2G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS06205
gene id: 438753:AZC_RS06205
uniprot id: A8HRK9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS22115
gene id: 438753:AZC_RS22115
uniprot id: A8HVG4
names: Similarity
messages: Belongs to the fabD family.

438753:AZC RS06400
gene id: 438753:AZC_RS06400
uniprot id: A8I0D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

438753:AZC RS05330
gene id: 438753:AZC_RS05330
uniprot id: A8HQJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

438753:AZC RS12365
gene id: 438753:AZC_RS12365
uniprot id: A8I6C0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

438753:AZC RS07205
gene id: 438753:AZC_RS07205
uniprot id: A8I1M2
names: Subcellular Location Annotation
messages: Cytoplasm

438753:AZC RS14800
gene id: 438753:AZC_RS14800
uniprot id: A8ICY9
names: Similarity
messages: Belongs to the sulfatase family.

438753:AZC RS04685
gene id: 438753:AZC_RS04685
uniprot id: A8HU69
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS12485
gene id: 438753:AZC_RS12485
uniprot id: A8I6I7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

438753:AZC RS15210
gene id: 438753:AZC_RS15210
uniprot id: A8IDI0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS23845
gene id: 438753:AZC_RS23845
uniprot id: P26487
names: Cofactor
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: FixJ, when activated by FixL, induces the expression of both nifA, required for activation of classical nif and fix genes, and fixK, required for fixN activation.
messages: Phosphorylated by FixL.

438753:AZC RS15580
gene id: 438753:AZC_RS15580
uniprot id: A8IE03
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS04060
gene id: 438753:AZC_RS04060
uniprot id: A8IQL6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

438753:AZC RS21180
gene id: 438753:AZC_RS21180
uniprot id: A8HS23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS18160
gene id: 438753:AZC_RS18160
uniprot id: A8IET0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

438753:AZC RS19270
gene id: 438753:AZC_RS19270
uniprot id: A8INE2
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS00270
gene id: 438753:AZC_RS00270
uniprot id: A8IG81
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS21185
gene id: 438753:AZC_RS21185
uniprot id: A8HS26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS04875
gene id: 438753:AZC_RS04875
uniprot id: A8HUI7
names: Subcellular Location Annotation
messages: Periplasm

438753:AZC RS14845
gene id: 438753:AZC_RS14845
uniprot id: A8ID14
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS18190
gene id: 438753:AZC_RS18190
uniprot id: A8IEU7
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

438753:AZC RS21105
gene id: 438753:AZC_RS21105
uniprot id: A8HRY9
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

438753:AZC RS17005
gene id: 438753:AZC_RS17005
uniprot id: A8IHN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

438753:AZC RS13220
gene id: 438753:AZC_RS13220
uniprot id: A8IAT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

438753:AZC RS16390
gene id: 438753:AZC_RS16390
uniprot id: A8IC94
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

438753:AZC RS08590
gene id: 438753:AZC_RS08590
uniprot id: A8I3U6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

438753:AZC RS08665
gene id: 438753:AZC_RS08665
uniprot id: A8I3Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

438753:AZC RS22265
gene id: 438753:AZC_RS22265
uniprot id: A8HVP9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

438753:AZC RS19450
gene id: 438753:AZC_RS19450
uniprot id: A8INQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS16015
gene id: 438753:AZC_RS16015
uniprot id: A8IBQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

438753:AZC RS04470
gene id: 438753:AZC_RS04470
uniprot id: A8HTU5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

438753:AZC RS01210
gene id: 438753:AZC_RS01210
uniprot id: A8IJ25
names: Similarity
messages: Belongs to the ros/MucR family.

438753:AZC RS16910
gene id: 438753:AZC_RS16910
uniprot id: A8IHI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS06620
gene id: 438753:AZC_RS06620
uniprot id: A8I0R2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

438753:AZC RS01220
gene id: 438753:AZC_RS01220
uniprot id: A8IJ29
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS21605
gene id: 438753:AZC_RS21605
uniprot id: A8HSR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS21255
gene id: 438753:AZC_RS21255
uniprot id: A8HS60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

438753:AZC RS05180
gene id: 438753:AZC_RS05180
uniprot id: A8HV50
names: Similarity
messages: Belongs to the YkuD family.

438753:AZC RS21830
gene id: 438753:AZC_RS21830
uniprot id: A8HT42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

438753:AZC RS03215
gene id: 438753:AZC_RS03215
uniprot id: A8IPJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

438753:AZC RS04515
gene id: 438753:AZC_RS04515
uniprot id: A8HTW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

438753:AZC RS22180
gene id: 438753:AZC_RS22180
uniprot id: A8HVK6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

438753:AZC RS19805
gene id: 438753:AZC_RS19805
uniprot id: A8IPC5
names: Similarity
messages: Belongs to the GSP E family.

438753:AZC RS12730
gene id: 438753:AZC_RS12730
uniprot id: A8IA38
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS10750
gene id: 438753:AZC_RS10750
uniprot id: A8I740
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M81 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).

438753:AZC RS23345
gene id: 438753:AZC_RS23345
uniprot id: A8HZ91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS05235
gene id: 438753:AZC_RS05235
uniprot id: A8HQ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

438753:AZC RS16890
gene id: 438753:AZC_RS16890
uniprot id: A8IHH8
names: Similarity
messages: Belongs to the UxaA family.

438753:AZC RS06935
gene id: 438753:AZC_RS06935
uniprot id: A8I191
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

438753:AZC RS05415
gene id: 438753:AZC_RS05415
uniprot id: A8HQR9
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

438753:AZC RS16305
gene id: 438753:AZC_RS16305
uniprot id: A8IC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS22125
gene id: 438753:AZC_RS22125
uniprot id: A8HVH0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

438753:AZC RS14510
gene id: 438753:AZC_RS14510
uniprot id: A8I9M0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

438753:AZC RS04135
gene id: 438753:AZC_RS04135
uniprot id: A8IQR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS09530
gene id: 438753:AZC_RS09530
uniprot id: A8I2A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS17725
gene id: 438753:AZC_RS17725
uniprot id: P26481
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

438753:AZC RS05310
gene id: 438753:AZC_RS05310
uniprot id: A8HQH1
names: Similarity
messages: Belongs to the NifX/NifY family.

438753:AZC RS17940
gene id: 438753:AZC_RS17940
uniprot id: A8IEG7
names: Similarity
messages: Belongs to the hyi family.

438753:AZC RS14850
gene id: 438753:AZC_RS14850
uniprot id: A8ID16
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS18860
gene id: 438753:AZC_RS18860
uniprot id: A8IFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

438753:AZC RS13600
gene id: 438753:AZC_RS13600
uniprot id: A8IB96
names: Subcellular Location Annotation
messages: Cell inner membrane

438753:AZC RS14755
gene id: 438753:AZC_RS14755
uniprot id: A8ICW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

438753:AZC RS12095
gene id: 438753:AZC_RS12095
uniprot id: A8I5Y1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

438753:AZC RS14875
gene id: 438753:AZC_RS14875
uniprot id: A8ID29
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

438753:AZC RS10425
gene id: 438753:AZC_RS10425
uniprot id: A8I3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS19730
gene id: 438753:AZC_RS19730
uniprot id: A8IP70
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

438753:AZC RS06190
gene id: 438753:AZC_RS06190
uniprot id: A8HRK3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

438753:AZC RS23680
gene id: 438753:AZC_RS23680
uniprot id: A8HZT3
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

438753:AZC RS17280
gene id: 438753:AZC_RS17280
uniprot id: A8II36
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS03080
gene id: 438753:AZC_RS03080
uniprot id: A8IMT9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

438753:AZC RS18930
gene id: 438753:AZC_RS18930
uniprot id: A8IMX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

438753:AZC RS21755
gene id: 438753:AZC_RS21755
uniprot id: A8HT01
names: Similarity
messages: Belongs to the SfsA family.

438753:AZC RS14550
gene id: 438753:AZC_RS14550
uniprot id: A8I9P3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

438753:AZC RS17710
gene id: 438753:AZC_RS17710
uniprot id: P26251
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-102 inactivates the nitrogenase reductase and regulates nitrogenase activity.

438753:AZC RS05225
gene id: 438753:AZC_RS05225
uniprot id: A8HQ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

438753:AZC RS11410
gene id: 438753:AZC_RS11410
uniprot id: A8I831
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

438753:AZC RS24065
gene id: 438753:AZC_RS24065
uniprot id: A8I235
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

438753:AZC RS16290
gene id: 438753:AZC_RS16290
uniprot id: A8IC42
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

438753:AZC RS01445
gene id: 438753:AZC_RS01445
uniprot id: A8IJC8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

438753:AZC RS17195
gene id: 438753:AZC_RS17195
uniprot id: A8IHZ0
names: Similarity
messages: Belongs to the UxaA family.

438753:AZC RS17070
gene id: 438753:AZC_RS17070
uniprot id: A8IHS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

438753:AZC RS20965
gene id: 438753:AZC_RS20965
uniprot id: A8HRS6
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

438753:AZC RS07415
gene id: 438753:AZC_RS07415
uniprot id: A8HWY1
names: Similarity
messages: Belongs to the leucine-binding protein family.

438753:AZC RS11750
gene id: 438753:AZC_RS11750
uniprot id: A8I5F3
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS04770
gene id: 438753:AZC_RS04770
uniprot id: A8HUC2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

438753:AZC RS22705
gene id: 438753:AZC_RS22705
uniprot id: A8HWH2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

438753:AZC RS10575
gene id: 438753:AZC_RS10575
uniprot id: A8I6T3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS02425
gene id: 438753:AZC_RS02425
uniprot id: A8IM34
names: Similarity
messages: Belongs to the leucine-binding protein family.

438753:AZC RS16240
gene id: 438753:AZC_RS16240
uniprot id: A8IC17
names: Similarity
messages: Belongs to the UPF0262 family.

438753:AZC RS06480
gene id: 438753:AZC_RS06480
uniprot id: A8I0H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

438753:AZC RS15650
gene id: 438753:AZC_RS15650
uniprot id: A8IE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

438753:AZC RS17845
gene id: 438753:AZC_RS17845
uniprot id: A8IEB3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

438753:AZC RS05160
gene id: 438753:AZC_RS05160
uniprot id: A8HV40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

438753:AZC RS10870
gene id: 438753:AZC_RS10870
uniprot id: A8I7A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

438753:AZC RS01605
gene id: 438753:AZC_RS01605
uniprot id: A8IJJ5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

438753:AZC RS05200
gene id: 438753:AZC_RS05200
uniprot id: A8HQ27
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

438753:AZC RS06155
gene id: 438753:AZC_RS06155
uniprot id: A8HRI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

438753:AZC RS09160
gene id: 438753:AZC_RS09160
uniprot id: A8I4S1
names: Similarity
messages: Belongs to the Gfa family.

438753:AZC RS21155
gene id: 438753:AZC_RS21155
uniprot id: A8HS10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

438753:AZC RS14745
gene id: 438753:AZC_RS14745
uniprot id: A8ICW0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

438753:AZC RS05945
gene id: 438753:AZC_RS05945
uniprot id: A8HRA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

438753:AZC RS19240
gene id: 438753:AZC_RS19240
uniprot id: A8INC6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

438753:AZC RS19370
gene id: 438753:AZC_RS19370
uniprot id: A8INK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

438753:AZC RS04010
gene id: 438753:AZC_RS04010
uniprot id: A8IQI2
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

438753:AZC RS16885
gene id: 438753:AZC_RS16885
uniprot id: A8IHH7
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS11420
gene id: 438753:AZC_RS11420
uniprot id: A8I836
names: Similarity
messages: Belongs to the TrpC family.

438753:AZC RS03905
gene id: 438753:AZC_RS03905
uniprot id: A8IQB9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

438753:AZC RS07100
gene id: 438753:AZC_RS07100
uniprot id: A8I1I1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

438753:AZC RS00095
gene id: 438753:AZC_RS00095
uniprot id: A8IG18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

438753:AZC RS22140
gene id: 438753:AZC_RS22140
uniprot id: A8HVI0
names: Similarity
messages: Belongs to the YicC/YloC family.

438753:AZC RS20500
gene id: 438753:AZC_RS20500
uniprot id: A8IL70
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

438753:AZC RS21160
gene id: 438753:AZC_RS21160
uniprot id: A8HS13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

438753:AZC RS02925
gene id: 438753:AZC_RS02925
uniprot id: A8IML8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

438753:AZC RS04560
gene id: 438753:AZC_RS04560
uniprot id: A8HTZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

438753:AZC RS23020
gene id: 438753:AZC_RS23020
uniprot id: A8HYR1
names: Similarity
messages: Belongs to the aspartokinase family.

438753:AZC RS02685
gene id: 438753:AZC_RS02685
uniprot id: A8IMC8
names: Similarity
messages: Belongs to the CFA/CMAS family.

438753:AZC RS14775
gene id: 438753:AZC_RS14775
uniprot id: A8ICX7
names: Similarity
messages: Belongs to the DapA family.

438753:AZC RS20210
gene id: 438753:AZC_RS20210
uniprot id: A8IKQ4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

438753:AZC RS23900
gene id: 438753:AZC_RS23900
uniprot id: A8I047
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

438753:AZC RS03200
gene id: 438753:AZC_RS03200
uniprot id: A8IPI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

438753:AZC RS16705
gene id: 438753:AZC_RS16705
uniprot id: A8ICR4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

438753:AZC RS23145
gene id: 438753:AZC_RS23145
uniprot id: A8HYY8
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS21950
gene id: 438753:AZC_RS21950
uniprot id: A8HV64
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

438753:AZC RS19145
gene id: 438753:AZC_RS19145
uniprot id: A8IN83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

438753:AZC RS20340
gene id: 438753:AZC_RS20340
uniprot id: A8IKY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

438753:AZC RS07785
gene id: 438753:AZC_RS07785
uniprot id: A8HXK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS10470
gene id: 438753:AZC_RS10470
uniprot id: A8I3G3
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS10375
gene id: 438753:AZC_RS10375
uniprot id: A8I3B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

438753:AZC RS04655
gene id: 438753:AZC_RS04655
uniprot id: A8HU50
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

438753:AZC RS23140
gene id: 438753:AZC_RS23140
uniprot id: A8HYY5
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS18730
gene id: 438753:AZC_RS18730
uniprot id: A8IFN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS17390
gene id: 438753:AZC_RS17390
uniprot id: A8II99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

438753:AZC RS21955
gene id: 438753:AZC_RS21955
uniprot id: A8HV65
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

438753:AZC RS06380
gene id: 438753:AZC_RS06380
uniprot id: A8I0C1
names: Similarity
messages: Belongs to the DSD1 family.

438753:AZC RS09825
gene id: 438753:AZC_RS09825
uniprot id: A8I2L3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS21345
gene id: 438753:AZC_RS21345
uniprot id: A8HSB3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS02195
gene id: 438753:AZC_RS02195
uniprot id: A8ILW3
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

438753:AZC RS09545
gene id: 438753:AZC_RS09545
uniprot id: A8I2A6
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

438753:AZC RS19460
gene id: 438753:AZC_RS19460
uniprot id: A8INR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS15830
gene id: 438753:AZC_RS15830
uniprot id: A8IBG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

438753:AZC RS00060
gene id: 438753:AZC_RS00060
uniprot id: A8IG07
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

438753:AZC RS04715
gene id: 438753:AZC_RS04715
uniprot id: A8HU90
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS19385
gene id: 438753:AZC_RS19385
uniprot id: A8INL2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS02200
gene id: 438753:AZC_RS02200
uniprot id: A8ILW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

438753:AZC RS03160
gene id: 438753:AZC_RS03160
uniprot id: A8IPG5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS12690
gene id: 438753:AZC_RS12690
uniprot id: A8IA17
names: Similarity
messages: Belongs to the YciI family.

438753:AZC RS20280
gene id: 438753:AZC_RS20280
uniprot id: A8IKU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

438753:AZC RS12980
gene id: 438753:AZC_RS12980
uniprot id: A8IAH5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

438753:AZC RS03475
gene id: 438753:AZC_RS03475
uniprot id: A8IPR5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

438753:AZC RS22505
gene id: 438753:AZC_RS22505
uniprot id: A8HW50
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

438753:AZC RS11940
gene id: 438753:AZC_RS11940
uniprot id: A8I5P9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS03635
gene id: 438753:AZC_RS03635
uniprot id: A8IPX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

438753:AZC RS26270
gene id: 438753:AZC_RS26270
uniprot id: A8IQ86
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS12780
gene id: 438753:AZC_RS12780
uniprot id: A8IA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS19440
gene id: 438753:AZC_RS19440
uniprot id: A8INP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS01510
gene id: 438753:AZC_RS01510
uniprot id: A8IJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

438753:AZC RS21335
gene id: 438753:AZC_RS21335
uniprot id: A8HSA6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

438753:AZC RS23865
gene id: 438753:AZC_RS23865
uniprot id: A8I031
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

438753:AZC RS12820
gene id: 438753:AZC_RS12820
uniprot id: A8IA87
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

438753:AZC RS14735
gene id: 438753:AZC_RS14735
uniprot id: A8ICV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

438753:AZC RS21050
gene id: 438753:AZC_RS21050
uniprot id: A8HRW2
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS08915
gene id: 438753:AZC_RS08915
uniprot id: A8I4D7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

438753:AZC RS15740
gene id: 438753:AZC_RS15740
uniprot id: A8IE85
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

438753:AZC RS11960
gene id: 438753:AZC_RS11960
uniprot id: A8I5R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

438753:AZC RS14880
gene id: 438753:AZC_RS14880
uniprot id: A8ID33
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

438753:AZC RS08720
gene id: 438753:AZC_RS08720
uniprot id: A8I418
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

438753:AZC RS23305
gene id: 438753:AZC_RS23305
uniprot id: A8HZ71
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

438753:AZC RS11715
gene id: 438753:AZC_RS11715
uniprot id: A8I5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

438753:AZC RS12715
gene id: 438753:AZC_RS12715
uniprot id: A8IA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

438753:AZC RS08105
gene id: 438753:AZC_RS08105
uniprot id: A8HY16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

438753:AZC RS20275
gene id: 438753:AZC_RS20275
uniprot id: A8IKU3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

438753:AZC RS17210
gene id: 438753:AZC_RS17210
uniprot id: A8IHZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

438753:AZC RS13655
gene id: 438753:AZC_RS13655
uniprot id: A8IBB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS15245
gene id: 438753:AZC_RS15245
uniprot id: A8IDJ4
names: Similarity
messages: Belongs to the peptidase S58 family.

438753:AZC RS10550
gene id: 438753:AZC_RS10550
uniprot id: A8I6R9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

438753:AZC RS11680
gene id: 438753:AZC_RS11680
uniprot id: A8I5C0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

438753:AZC RS16575
gene id: 438753:AZC_RS16575
uniprot id: A8ICI9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

438753:AZC RS06545
gene id: 438753:AZC_RS06545
uniprot id: A8I0L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

438753:AZC RS12530
gene id: 438753:AZC_RS12530
uniprot id: A8I6K9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

438753:AZC RS02530
gene id: 438753:AZC_RS02530
uniprot id: A8IM67
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

438753:AZC RS15155
gene id: 438753:AZC_RS15155
uniprot id: A8IDF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YfcJ family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS21310
gene id: 438753:AZC_RS21310
uniprot id: A8HS90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

438753:AZC RS16155
gene id: 438753:AZC_RS16155
uniprot id: A8IBX3
names: Similarity
messages: Belongs to the GST superfamily.

438753:AZC RS22665
gene id: 438753:AZC_RS22665
uniprot id: A8HWF1
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS17260
gene id: 438753:AZC_RS17260
uniprot id: A8II25
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS14870
gene id: 438753:AZC_RS14870
uniprot id: A8ID26
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

438753:AZC RS10115
gene id: 438753:AZC_RS10115
uniprot id: A8I2X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS17540
gene id: 438753:AZC_RS17540
uniprot id: A8III1
names: Similarity
messages: Belongs to the HesB/IscA family.

438753:AZC RS16085
gene id: 438753:AZC_RS16085
uniprot id: A8IBU0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

438753:AZC RS22010
gene id: 438753:AZC_RS22010
uniprot id: A8HV96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

438753:AZC RS01425
gene id: 438753:AZC_RS01425
uniprot id: A8IJB8
names: Similarity
messages: Belongs to the peptidase A24 family.

438753:AZC RS17735
gene id: 438753:AZC_RS17735
uniprot id: P26483
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: FixA and FixB form a heterodimer.
messages: May play a role in a redox process involved in nitrogen fixation.

438753:AZC RS17780
gene id: 438753:AZC_RS17780
uniprot id: A8IIV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

438753:AZC RS17135
gene id: 438753:AZC_RS17135
uniprot id: A8IHV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

438753:AZC RS10310
gene id: 438753:AZC_RS10310
uniprot id: A8I376
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS18020
gene id: 438753:AZC_RS18020
uniprot id: A8IEK9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

438753:AZC RS17935
gene id: 438753:AZC_RS17935
uniprot id: A8IEG4
names: Similarity
messages: Belongs to the TPP enzyme family.

438753:AZC RS17495
gene id: 438753:AZC_RS17495
uniprot id: A8IIF6
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

438753:AZC RS18530
gene id: 438753:AZC_RS18530
uniprot id: A8IFA9
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: Single-chain monomer with multiple functions.

438753:AZC RS16385
gene id: 438753:AZC_RS16385
uniprot id: A8IC91
names: Subcellular Location Annotation
messages: Periplasm

438753:AZC RS00925
gene id: 438753:AZC_RS00925
uniprot id: A8IH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

438753:AZC RS21925
gene id: 438753:AZC_RS21925
uniprot id: A8HV58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

438753:AZC RS12680
gene id: 438753:AZC_RS12680
uniprot id: A8IA12
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

438753:AZC RS13170
gene id: 438753:AZC_RS13170
uniprot id: A8IAR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

438753:AZC RS10265
gene id: 438753:AZC_RS10265
uniprot id: A8I350
names: Similarity
messages: Belongs to the ros/MucR family.

438753:AZC RS10155
gene id: 438753:AZC_RS10155
uniprot id: A8I2Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS06060
gene id: 438753:AZC_RS06060
uniprot id: A8HRF3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

438753:AZC RS21470
gene id: 438753:AZC_RS21470
uniprot id: A8HSI8
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS00290
gene id: 438753:AZC_RS00290
uniprot id: A8IG91
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

438753:AZC RS14505
gene id: 438753:AZC_RS14505
uniprot id: A8I9L7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

438753:AZC RS16320
gene id: 438753:AZC_RS16320
uniprot id: A8IC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS03305
gene id: 438753:AZC_RS03305
uniprot id: A8IPL7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

438753:AZC RS14095
gene id: 438753:AZC_RS14095
uniprot id: A8I8Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

438753:AZC RS20430
gene id: 438753:AZC_RS20430
uniprot id: A8IL31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

438753:AZC RS07550
gene id: 438753:AZC_RS07550
uniprot id: A8HX65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

438753:AZC RS13960
gene id: 438753:AZC_RS13960
uniprot id: A8I8S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

438753:AZC RS10440
gene id: 438753:AZC_RS10440
uniprot id: A8I3E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS00320
gene id: 438753:AZC_RS00320
uniprot id: A8IGA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

438753:AZC RS19250
gene id: 438753:AZC_RS19250
uniprot id: A8IND2
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

438753:AZC RS22595
gene id: 438753:AZC_RS22595
uniprot id: A8HWA7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

438753:AZC RS10175
gene id: 438753:AZC_RS10175
uniprot id: A8I302
names: Function
messages: Acts on leucine, isoleucine and valine.

438753:AZC RS08680
gene id: 438753:AZC_RS08680
uniprot id: A8I3Z6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

438753:AZC RS02780
gene id: 438753:AZC_RS02780
uniprot id: A8IMG3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

438753:AZC RS10605
gene id: 438753:AZC_RS10605
uniprot id: A8I6V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS02930
gene id: 438753:AZC_RS02930
uniprot id: A8IML9
names: Similarity
messages: Belongs to the HIBADH-related family.

438753:AZC RS05210
gene id: 438753:AZC_RS05210
uniprot id: A8HQ40
names: Similarity
messages: Belongs to the TrpF family.

438753:AZC RS03855
gene id: 438753:AZC_RS03855
uniprot id: A8IQ83
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS03045
gene id: 438753:AZC_RS03045
uniprot id: A8IMS3
names: Similarity
messages: Belongs to the peptidase A31 family.

438753:AZC RS03685
gene id: 438753:AZC_RS03685
uniprot id: A8IPZ4
names: Function
names: Similarity
messages: Belongs to the amidase family.
messages: Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).

438753:AZC RS11625
gene id: 438753:AZC_RS11625
uniprot id: A8I592
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

438753:AZC RS02385
gene id: 438753:AZC_RS02385
uniprot id: A8IM23
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS18920
gene id: 438753:AZC_RS18920
uniprot id: A8IMX3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

438753:AZC RS06285
gene id: 438753:AZC_RS06285
uniprot id: A8I072
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

438753:AZC RS08515
gene id: 438753:AZC_RS08515
uniprot id: A8I3P9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

438753:AZC RS02545
gene id: 438753:AZC_RS02545
uniprot id: A8IM72
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

438753:AZC RS09165
gene id: 438753:AZC_RS09165
uniprot id: A8I4S4
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

438753:AZC RS14925
gene id: 438753:AZC_RS14925
uniprot id: A8ID59
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

438753:AZC RS09585
gene id: 438753:AZC_RS09585
uniprot id: A8I2C1
names: Similarity
messages: Belongs to the FBPase class 2 family.

438753:AZC RS24130
gene id: 438753:AZC_RS24130
uniprot id: A8I266
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

438753:AZC RS02660
gene id: 438753:AZC_RS02660
uniprot id: A8IMB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

438753:AZC RS00750
gene id: 438753:AZC_RS00750
uniprot id: A8IGY0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

438753:AZC RS19295
gene id: 438753:AZC_RS19295
uniprot id: A8INF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS13285
gene id: 438753:AZC_RS13285
uniprot id: A8IAW2
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

438753:AZC RS12640
gene id: 438753:AZC_RS12640
uniprot id: A8I9Z1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

438753:AZC RS11395
gene id: 438753:AZC_RS11395
uniprot id: A8I822
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS18835
gene id: 438753:AZC_RS18835
uniprot id: A8IFW0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

438753:AZC RS05170
gene id: 438753:AZC_RS05170
uniprot id: A8HV46
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

438753:AZC RS15030
gene id: 438753:AZC_RS15030
uniprot id: A8IDB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS12505
gene id: 438753:AZC_RS12505
uniprot id: A8I6J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

438753:AZC RS18625
gene id: 438753:AZC_RS18625
uniprot id: A8IFG9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

438753:AZC RS23050
gene id: 438753:AZC_RS23050
uniprot id: A8HYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

438753:AZC RS01910
gene id: 438753:AZC_RS01910
uniprot id: A8IJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

438753:AZC RS00785
gene id: 438753:AZC_RS00785
uniprot id: A8IGZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

438753:AZC RS18940
gene id: 438753:AZC_RS18940
uniprot id: A8IMY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

438753:AZC RS06355
gene id: 438753:AZC_RS06355
uniprot id: A8I0A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS18195
gene id: 438753:AZC_RS18195
uniprot id: A8IEU9
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

438753:AZC RS21145
gene id: 438753:AZC_RS21145
uniprot id: A8HS07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS23880
gene id: 438753:AZC_RS23880
uniprot id: A8I039
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

438753:AZC RS05885
gene id: 438753:AZC_RS05885
uniprot id: A8HR94
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

438753:AZC RS06730
gene id: 438753:AZC_RS06730
uniprot id: A8I0Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

438753:AZC RS22700
gene id: 438753:AZC_RS22700
uniprot id: A8HWG9
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS10525
gene id: 438753:AZC_RS10525
uniprot id: A8I6Q6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

438753:AZC RS08420
gene id: 438753:AZC_RS08420
uniprot id: A8HYJ2
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

438753:AZC RS17355
gene id: 438753:AZC_RS17355
uniprot id: A8II77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

438753:AZC RS07485
gene id: 438753:AZC_RS07485
uniprot id: A8HX25
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

438753:AZC RS02615
gene id: 438753:AZC_RS02615
uniprot id: A8IM99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

438753:AZC RS16620
gene id: 438753:AZC_RS16620
uniprot id: A8ICL3
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS04805
gene id: 438753:AZC_RS04805
uniprot id: A8HUE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

438753:AZC RS03340
gene id: 438753:AZC_RS03340
uniprot id: A8IPM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

438753:AZC RS05165
gene id: 438753:AZC_RS05165
uniprot id: A8HV43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

438753:AZC RS11255
gene id: 438753:AZC_RS11255
uniprot id: A8I7W3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

438753:AZC RS23660
gene id: 438753:AZC_RS23660
uniprot id: A8HZS2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

438753:AZC RS08870
gene id: 438753:AZC_RS08870
uniprot id: A8I4A9
names: Similarity
messages: Belongs to the citrate synthase family.

438753:AZC RS11300
gene id: 438753:AZC_RS11300
uniprot id: A8I7Y0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS20660
gene id: 438753:AZC_RS20660
uniprot id: A8ILF9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

438753:AZC RS05335
gene id: 438753:AZC_RS05335
uniprot id: P26252
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-102 inactivates the nitrogenase reductase and regulates nitrogenase activity.

438753:AZC RS15890
gene id: 438753:AZC_RS15890
uniprot id: Q43971
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Seems to be involved in the regulation of NifA.

438753:AZC RS14490
gene id: 438753:AZC_RS14490
uniprot id: A8I9K9
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

438753:AZC RS16520
gene id: 438753:AZC_RS16520
uniprot id: A8ICG0
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS12330
gene id: 438753:AZC_RS12330
uniprot id: A8I6A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

438753:AZC RS09935
gene id: 438753:AZC_RS09935
uniprot id: A8I2Q5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

438753:AZC RS10305
gene id: 438753:AZC_RS10305
uniprot id: A8I373
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS03050
gene id: 438753:AZC_RS03050
uniprot id: A8IMS5
names: Similarity
messages: Belongs to the HupF/HypC family.

438753:AZC RS16340
gene id: 438753:AZC_RS16340
uniprot id: A8IC68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS18825
gene id: 438753:AZC_RS18825
uniprot id: A8IFV3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

438753:AZC RS22290
gene id: 438753:AZC_RS22290
uniprot id: A8HVR3
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

438753:AZC RS03735
gene id: 438753:AZC_RS03735
uniprot id: A8IQ17
names: Similarity
messages: Belongs to the DapA family.

438753:AZC RS12270
gene id: 438753:AZC_RS12270
uniprot id: A8I669
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS19675
gene id: 438753:AZC_RS19675
uniprot id: A8IP35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

438753:AZC RS00310
gene id: 438753:AZC_RS00310
uniprot id: A8IGA0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

438753:AZC RS19285
gene id: 438753:AZC_RS19285
uniprot id: A8INF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

438753:AZC RS06490
gene id: 438753:AZC_RS06490
uniprot id: A8I0I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS17085
gene id: 438753:AZC_RS17085
uniprot id: A8IHT1
names: Similarity
messages: Belongs to the UPF0235 family.

438753:AZC RS13155
gene id: 438753:AZC_RS13155
uniprot id: A8IAQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

438753:AZC RS13185
gene id: 438753:AZC_RS13185
uniprot id: A8IAR6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

438753:AZC RS08795
gene id: 438753:AZC_RS08795
uniprot id: A8I467
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

438753:AZC RS14315
gene id: 438753:AZC_RS14315
uniprot id: A8I9B6
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

438753:AZC RS05410
gene id: 438753:AZC_RS05410
uniprot id: A8HQR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS10285
gene id: 438753:AZC_RS10285
uniprot id: A8I361
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS02320
gene id: 438753:AZC_RS02320
uniprot id: A8IM01
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

438753:AZC RS04825
gene id: 438753:AZC_RS04825
uniprot id: A8HUG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

438753:AZC RS20995
gene id: 438753:AZC_RS20995
uniprot id: A8HRT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

438753:AZC RS06570
gene id: 438753:AZC_RS06570
uniprot id: A8I0N1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

438753:AZC RS08270
gene id: 438753:AZC_RS08270
uniprot id: A8HYB1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

438753:AZC RS07680
gene id: 438753:AZC_RS07680
uniprot id: A8HXE5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

438753:AZC RS25540
gene id: 438753:AZC_RS25540
uniprot id: A8ID82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

438753:AZC RS07690
gene id: 438753:AZC_RS07690
uniprot id: A8HXF1
names: Similarity
messages: Belongs to the GcvT family.

438753:AZC RS03295
gene id: 438753:AZC_RS03295
uniprot id: A8IPL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm
messages: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.

438753:AZC RS22520
gene id: 438753:AZC_RS22520
uniprot id: A8HW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS08835
gene id: 438753:AZC_RS08835
uniprot id: A8I489
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

438753:AZC RS01435
gene id: 438753:AZC_RS01435
uniprot id: A8IJC3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS00025
gene id: 438753:AZC_RS00025
uniprot id: A8IFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

438753:AZC RS23495
gene id: 438753:AZC_RS23495
uniprot id: A8HZI3
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS22175
gene id: 438753:AZC_RS22175
uniprot id: A8HVK3
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS10070
gene id: 438753:AZC_RS10070
uniprot id: A8I2V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS16840
gene id: 438753:AZC_RS16840
uniprot id: A8IHF5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

438753:AZC RS19420
gene id: 438753:AZC_RS19420
uniprot id: A8INN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS14070
gene id: 438753:AZC_RS14070
uniprot id: A8I8Y4
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

438753:AZC RS20595
gene id: 438753:AZC_RS20595
uniprot id: A8ILC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

438753:AZC RS11280
gene id: 438753:AZC_RS11280
uniprot id: A8I7X2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

438753:AZC RS07790
gene id: 438753:AZC_RS07790
uniprot id: A8HXK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS10445
gene id: 438753:AZC_RS10445
uniprot id: A8I3E8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

438753:AZC RS23925
gene id: 438753:AZC_RS23925
uniprot id: A8I060
names: Function
names: Similarity
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

438753:AZC RS00400
gene id: 438753:AZC_RS00400
uniprot id: A8IGE9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

438753:AZC RS14135
gene id: 438753:AZC_RS14135
uniprot id: A8I920
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS16510
gene id: 438753:AZC_RS16510
uniprot id: A8ICF5
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS10700
gene id: 438753:AZC_RS10700
uniprot id: A8I711
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

438753:AZC RS02110
gene id: 438753:AZC_RS02110
uniprot id: A8ILU0
names: Similarity
messages: Belongs to the histone deacetylase family.

438753:AZC RS16440
gene id: 438753:AZC_RS16440
uniprot id: A8ICB9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

438753:AZC RS05100
gene id: 438753:AZC_RS05100
uniprot id: A8HUZ8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

438753:AZC RS01345
gene id: 438753:AZC_RS01345
uniprot id: A8IJ85
names: Subcellular Location Annotation
messages: Nucleus

438753:AZC RS10915
gene id: 438753:AZC_RS10915
uniprot id: A8I7D5
names: Similarity
messages: Belongs to the leucine-binding protein family.

438753:AZC RS23690
gene id: 438753:AZC_RS23690
uniprot id: A8HZT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

438753:AZC RS15835
gene id: 438753:AZC_RS15835
uniprot id: A8IBH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

438753:AZC RS19995
gene id: 438753:AZC_RS19995
uniprot id: A8IKE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

438753:AZC RS23940
gene id: 438753:AZC_RS23940
uniprot id: A8I1W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

438753:AZC RS03495
gene id: 438753:AZC_RS03495
uniprot id: A8IPS1
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS01180
gene id: 438753:AZC_RS01180
uniprot id: A8IJ11
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

438753:AZC RS01765
gene id: 438753:AZC_RS01765
uniprot id: A8IJR8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

438753:AZC RS00075
gene id: 438753:AZC_RS00075
uniprot id: A8IG12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

438753:AZC RS19565
gene id: 438753:AZC_RS19565
uniprot id: A8INW8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

438753:AZC RS20015
gene id: 438753:AZC_RS20015
uniprot id: A8IKF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS03455
gene id: 438753:AZC_RS03455
uniprot id: A8IPQ8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

438753:AZC RS03240
gene id: 438753:AZC_RS03240
uniprot id: A8IPK0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

438753:AZC RS13005
gene id: 438753:AZC_RS13005
uniprot id: A8IAJ0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS13000
gene id: 438753:AZC_RS13000
uniprot id: A8IAI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

438753:AZC RS17055
gene id: 438753:AZC_RS17055
uniprot id: A8IHR6
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS14150
gene id: 438753:AZC_RS14150
uniprot id: A8I928
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

438753:AZC RS17730
gene id: 438753:AZC_RS17730
uniprot id: P26482
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: FixA and FixB form a heterodimer.
messages: May play a role in a redox process involved in nitrogen fixation.

438753:AZC RS10900
gene id: 438753:AZC_RS10900
uniprot id: A8I7C6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

438753:AZC RS16105
gene id: 438753:AZC_RS16105
uniprot id: A8IBU8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS01460
gene id: 438753:AZC_RS01460
uniprot id: A8IJD5
names: Function
names: Similarity
messages: Belongs to the ADC family.
messages: Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.

438753:AZC RS05070
gene id: 438753:AZC_RS05070
uniprot id: A8HUX3
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS17480
gene id: 438753:AZC_RS17480
uniprot id: A8IIE7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS05955
gene id: 438753:AZC_RS05955
uniprot id: A8HRB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

438753:AZC RS01275
gene id: 438753:AZC_RS01275
uniprot id: A8IJ52
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

438753:AZC RS09835
gene id: 438753:AZC_RS09835
uniprot id: A8I2L7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

438753:AZC RS14140
gene id: 438753:AZC_RS14140
uniprot id: A8I922
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS16180
gene id: 438753:AZC_RS16180
uniprot id: A8IBY5
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

438753:AZC RS09035
gene id: 438753:AZC_RS09035
uniprot id: A8I4K7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

438753:AZC RS13660
gene id: 438753:AZC_RS13660
uniprot id: A8IBC0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS17975
gene id: 438753:AZC_RS17975
uniprot id: A8IEI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

438753:AZC RS17590
gene id: 438753:AZC_RS17590
uniprot id: A8IIK9
names: Similarity
messages: Belongs to the NifZ family.

438753:AZC RS13770
gene id: 438753:AZC_RS13770
uniprot id: A8I8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS16935
gene id: 438753:AZC_RS16935
uniprot id: A8IHK1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

438753:AZC RS25485
gene id: 438753:AZC_RS25485
uniprot id: A8I7M0
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

438753:AZC RS00315
gene id: 438753:AZC_RS00315
uniprot id: A8IGA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

438753:AZC RS13080
gene id: 438753:AZC_RS13080
uniprot id: A8IAN3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

438753:AZC RS20110
gene id: 438753:AZC_RS20110
uniprot id: A8IKK0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

438753:AZC RS14125
gene id: 438753:AZC_RS14125
uniprot id: A8I913
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS15380
gene id: 438753:AZC_RS15380
uniprot id: A8IDQ5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

438753:AZC RS00680
gene id: 438753:AZC_RS00680
uniprot id: A8IGU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

438753:AZC RS23385
gene id: 438753:AZC_RS23385
uniprot id: A8HZB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

438753:AZC RS00540
gene id: 438753:AZC_RS00540
uniprot id: A8IGM4
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

438753:AZC RS00595
gene id: 438753:AZC_RS00595
uniprot id: A8IGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

438753:AZC RS17220
gene id: 438753:AZC_RS17220
uniprot id: A8II05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS20220
gene id: 438753:AZC_RS20220
uniprot id: A8IKR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

438753:AZC RS23280
gene id: 438753:AZC_RS23280
uniprot id: A8HZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

438753:AZC RS13645
gene id: 438753:AZC_RS13645
uniprot id: A8IBB2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

438753:AZC RS01420
gene id: 438753:AZC_RS01420
uniprot id: A8IJB5
names: Similarity
messages: Belongs to the peptidase M17 family.

438753:AZC RS07545
gene id: 438753:AZC_RS07545
uniprot id: A8HX61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

438753:AZC RS10290
gene id: 438753:AZC_RS10290
uniprot id: A8I364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS03500
gene id: 438753:AZC_RS03500
uniprot id: A8IPS2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS03040
gene id: 438753:AZC_RS03040
uniprot id: A8IMS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

438753:AZC RS23615
gene id: 438753:AZC_RS23615
uniprot id: A8HZP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

438753:AZC RS06210
gene id: 438753:AZC_RS06210
uniprot id: A8HRL1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

438753:AZC RS19860
gene id: 438753:AZC_RS19860
uniprot id: A8IK73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS08220
gene id: 438753:AZC_RS08220
uniprot id: A8HY80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS10345
gene id: 438753:AZC_RS10345
uniprot id: A8I393
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

438753:AZC RS11970
gene id: 438753:AZC_RS11970
uniprot id: A8I5R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS12925
gene id: 438753:AZC_RS12925
uniprot id: A8IAE6
names: Function
names: Similarity
messages: Belongs to the amidase family.
messages: Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).

438753:AZC RS13230
gene id: 438753:AZC_RS13230
uniprot id: A8IAT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

438753:AZC RS13330
gene id: 438753:AZC_RS13330
uniprot id: A8IAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS02610
gene id: 438753:AZC_RS02610
uniprot id: A8IM98
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS23930
gene id: 438753:AZC_RS23930
uniprot id: A8I1V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

438753:AZC RS10720
gene id: 438753:AZC_RS10720
uniprot id: A8I722
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS01120
gene id: 438753:AZC_RS01120
uniprot id: A8IIZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

438753:AZC RS15655
gene id: 438753:AZC_RS15655
uniprot id: A8IE40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

438753:AZC RS22500
gene id: 438753:AZC_RS22500
uniprot id: A8HW45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS01725
gene id: 438753:AZC_RS01725
uniprot id: A8IJQ0
names: Similarity
messages: Belongs to the YkuD family.

438753:AZC RS10760
gene id: 438753:AZC_RS10760
uniprot id: A8I746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS06815
gene id: 438753:AZC_RS06815
uniprot id: A8I126
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

438753:AZC RS13160
gene id: 438753:AZC_RS13160
uniprot id: A8IAQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

438753:AZC RS13755
gene id: 438753:AZC_RS13755
uniprot id: A8I8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS02165
gene id: 438753:AZC_RS02165
uniprot id: A8ILV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

438753:AZC RS06650
gene id: 438753:AZC_RS06650
uniprot id: A8I0T7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS20560
gene id: 438753:AZC_RS20560
uniprot id: A8ILA5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

438753:AZC RS22860
gene id: 438753:AZC_RS22860
uniprot id: A8HWQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

438753:AZC RS14890
gene id: 438753:AZC_RS14890
uniprot id: A8ID39
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS13940
gene id: 438753:AZC_RS13940
uniprot id: A8I8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS09300
gene id: 438753:AZC_RS09300
uniprot id: A8I507
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS07575
gene id: 438753:AZC_RS07575
uniprot id: A8HX81
names: Similarity
messages: Belongs to the universal stress protein A family.

438753:AZC RS15910
gene id: 438753:AZC_RS15910
uniprot id: Q04850
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Member of the two-component regulatory system NtrY/NtrX involved in nitrogen level control. Probably activates NtrX by phosphorylation.

438753:AZC RS08120
gene id: 438753:AZC_RS08120
uniprot id: A8HY24
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS22345
gene id: 438753:AZC_RS22345
uniprot id: A8HVU3
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS17380
gene id: 438753:AZC_RS17380
uniprot id: A8II93
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

438753:AZC RS12420
gene id: 438753:AZC_RS12420
uniprot id: A8I6F1
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

438753:AZC RS11590
gene id: 438753:AZC_RS11590
uniprot id: A8I578
names: Similarity
messages: Belongs to the threonine synthase family.

438753:AZC RS08875
gene id: 438753:AZC_RS08875
uniprot id: A8I4B2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

438753:AZC RS00090
gene id: 438753:AZC_RS00090
uniprot id: A8IG16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

438753:AZC RS10395
gene id: 438753:AZC_RS10395
uniprot id: A8I3C0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

438753:AZC RS09670
gene id: 438753:AZC_RS09670
uniprot id: A8I2F4
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

438753:AZC RS10180
gene id: 438753:AZC_RS10180
uniprot id: A8I304
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS10510
gene id: 438753:AZC_RS10510
uniprot id: A8I3I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS19105
gene id: 438753:AZC_RS19105
uniprot id: A8IN61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

438753:AZC RS06975
gene id: 438753:AZC_RS06975
uniprot id: A8I1B4
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell inner membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

438753:AZC RS13205
gene id: 438753:AZC_RS13205
uniprot id: A8IAS6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

438753:AZC RS14305
gene id: 438753:AZC_RS14305
uniprot id: A8I9B1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

438753:AZC RS03325
gene id: 438753:AZC_RS03325
uniprot id: A8IPM4
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

438753:AZC RS12110
gene id: 438753:AZC_RS12110
uniprot id: A8I5Z0
names: Similarity
messages: Belongs to the YciI family.

438753:AZC RS23065
gene id: 438753:AZC_RS23065
uniprot id: A8HYT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

438753:AZC RS11550
gene id: 438753:AZC_RS11550
uniprot id: A8I8B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

438753:AZC RS15470
gene id: 438753:AZC_RS15470
uniprot id: A8IDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS15275
gene id: 438753:AZC_RS15275
uniprot id: A8IDK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

438753:AZC RS23235
gene id: 438753:AZC_RS23235
uniprot id: A8HZ40
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

438753:AZC RS03260
gene id: 438753:AZC_RS03260
uniprot id: A8IPK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

438753:AZC RS22785
gene id: 438753:AZC_RS22785
uniprot id: A8HWK4
names: Similarity
messages: Belongs to the glutamine synthetase family.

438753:AZC RS03805
gene id: 438753:AZC_RS03805
uniprot id: A8IQ54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

438753:AZC RS23030
gene id: 438753:AZC_RS23030
uniprot id: A8HYR7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

438753:AZC RS17990
gene id: 438753:AZC_RS17990
uniprot id: A8IEJ4
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

438753:AZC RS20700
gene id: 438753:AZC_RS20700
uniprot id: A8ILI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

438753:AZC RS04790
gene id: 438753:AZC_RS04790
uniprot id: A8HUD6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

438753:AZC RS11400
gene id: 438753:AZC_RS11400
uniprot id: A8I825
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

438753:AZC RS20060
gene id: 438753:AZC_RS20060
uniprot id: A8IKH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS08690
gene id: 438753:AZC_RS08690
uniprot id: A8I402
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

438753:AZC RS11270
gene id: 438753:AZC_RS11270
uniprot id: A8I7W9
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

438753:AZC RS04720
gene id: 438753:AZC_RS04720
uniprot id: A8HU93
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

438753:AZC RS22160
gene id: 438753:AZC_RS22160
uniprot id: A8HVJ3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

438753:AZC RS02355
gene id: 438753:AZC_RS02355
uniprot id: A8IM13
names: Similarity
messages: Belongs to the ketopantoate reductase family.

438753:AZC RS22570
gene id: 438753:AZC_RS22570
uniprot id: A8HW93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS09355
gene id: 438753:AZC_RS09355
uniprot id: A8I530
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS05490
gene id: 438753:AZC_RS05490
uniprot id: A8HQX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

438753:AZC RS00395
gene id: 438753:AZC_RS00395
uniprot id: A8IGE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

438753:AZC RS19455
gene id: 438753:AZC_RS19455
uniprot id: A8INQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS06320
gene id: 438753:AZC_RS06320
uniprot id: A8I089
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

438753:AZC RS03190
gene id: 438753:AZC_RS03190
uniprot id: A8IPI2
names: Similarity
messages: Belongs to the MotB family.

438753:AZC RS02690
gene id: 438753:AZC_RS02690
uniprot id: A8IMD0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

438753:AZC RS19540
gene id: 438753:AZC_RS19540
uniprot id: A8INV7
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS13140
gene id: 438753:AZC_RS13140
uniprot id: A8IAQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

438753:AZC RS09690
gene id: 438753:AZC_RS09690
uniprot id: A8I2G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS08600
gene id: 438753:AZC_RS08600
uniprot id: A8I3V2
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

438753:AZC RS01990
gene id: 438753:AZC_RS01990
uniprot id: A8IK20
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

438753:AZC RS11745
gene id: 438753:AZC_RS11745
uniprot id: A8I5F1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
messages: Homooctamer; tetramer of dimers.
messages: Reaction proceeds via a syn dehydration.

438753:AZC RS15460
gene id: 438753:AZC_RS15460
uniprot id: A8IDU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS00660
gene id: 438753:AZC_RS00660
uniprot id: A8IGT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS01355
gene id: 438753:AZC_RS01355
uniprot id: A8IJ89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.
messages: Homotrimer.

438753:AZC RS14765
gene id: 438753:AZC_RS14765
uniprot id: A8ICX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

438753:AZC RS17700
gene id: 438753:AZC_RS17700
uniprot id: A8IIR7
names: Similarity
messages: Belongs to the ArsC family.

438753:AZC RS11655
gene id: 438753:AZC_RS11655
uniprot id: A8I5A9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS02735
gene id: 438753:AZC_RS02735
uniprot id: A8IME9
names: Similarity
messages: Belongs to the YoeB family.

438753:AZC RS23365
gene id: 438753:AZC_RS23365
uniprot id: A8HZA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

438753:AZC RS11575
gene id: 438753:AZC_RS11575
uniprot id: A8I572
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

438753:AZC RS15045
gene id: 438753:AZC_RS15045
uniprot id: A8IDB9
names: Similarity
messages: Belongs to the creatininase superfamily.

438753:AZC RS22850
gene id: 438753:AZC_RS22850
uniprot id: A8HWP5
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

438753:AZC RS08910
gene id: 438753:AZC_RS08910
uniprot id: A8I4D4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

438753:AZC RS12065
gene id: 438753:AZC_RS12065
uniprot id: A8I5W9
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

438753:AZC RS15355
gene id: 438753:AZC_RS15355
uniprot id: A8IDP5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

438753:AZC RS06280
gene id: 438753:AZC_RS06280
uniprot id: A8I069
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

438753:AZC RS21580
gene id: 438753:AZC_RS21580
uniprot id: A8HSP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

438753:AZC RS23785
gene id: 438753:AZC_RS23785
uniprot id: A8HZY6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

438753:AZC RS19835
gene id: 438753:AZC_RS19835
uniprot id: A8IPE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

438753:AZC RS08115
gene id: 438753:AZC_RS08115
uniprot id: A8HY21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

438753:AZC RS23790
gene id: 438753:AZC_RS23790
uniprot id: A8HZY9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

438753:AZC RS16535
gene id: 438753:AZC_RS16535
uniprot id: A8ICG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

438753:AZC RS10280
gene id: 438753:AZC_RS10280
uniprot id: A8I359
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS14860
gene id: 438753:AZC_RS14860
uniprot id: A8ID21
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

438753:AZC RS02550
gene id: 438753:AZC_RS02550
uniprot id: A8IM75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

438753:AZC RS08325
gene id: 438753:AZC_RS08325
uniprot id: A8HYE6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS20495
gene id: 438753:AZC_RS20495
uniprot id: A8IL67
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS18915
gene id: 438753:AZC_RS18915
uniprot id: A8IMX0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

438753:AZC RS16095
gene id: 438753:AZC_RS16095
uniprot id: A8IBU5
names: Similarity
messages: Belongs to the peptidase M1 family.

438753:AZC RS12190
gene id: 438753:AZC_RS12190
uniprot id: A8I630
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Membrane
messages: Secreted

438753:AZC RS03225
gene id: 438753:AZC_RS03225
uniprot id: A8IPJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

438753:AZC RS03920
gene id: 438753:AZC_RS03920
uniprot id: A8IQD5
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS11690
gene id: 438753:AZC_RS11690
uniprot id: A8I5C5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

438753:AZC RS20415
gene id: 438753:AZC_RS20415
uniprot id: A8IL23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

438753:AZC RS18650
gene id: 438753:AZC_RS18650
uniprot id: A8IFI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

438753:AZC RS03585
gene id: 438753:AZC_RS03585
uniprot id: A8IPV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

438753:AZC RS23015
gene id: 438753:AZC_RS23015
uniprot id: A8HYQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS24145
gene id: 438753:AZC_RS24145
uniprot id: A8I272
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

438753:AZC RS05105
gene id: 438753:AZC_RS05105
uniprot id: A8HV03
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

438753:AZC RS00535
gene id: 438753:AZC_RS00535
uniprot id: A8IGM1
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS17080
gene id: 438753:AZC_RS17080
uniprot id: A8IHS8
names: Similarity
messages: Belongs to the YggT family.

438753:AZC RS07170
gene id: 438753:AZC_RS07170
uniprot id: A8I1K9
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

438753:AZC RS00045
gene id: 438753:AZC_RS00045
uniprot id: A8IG00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

438753:AZC RS15505
gene id: 438753:AZC_RS15505
uniprot id: A8IDW1
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS16515
gene id: 438753:AZC_RS16515
uniprot id: A8ICF8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclic amide hydrolase (CyAH) family.
messages: Cyclic amide hydrolase of unknown substrate specificity. Catalyzes the hydrolytic ring-opening of a cyclic amide. Does not act on cyanuric acid nor barbituric acid.
messages: Homotetramer.
messages: The monomer structure is formed from three repeating units (RUs) that share the same structure as one another. The monomer and the active site possess nearly threefold rotational symmetry, to the extent that the active site possesses three potential Ser-Lys catalytic dyads, but one of the 3 active site surfaces varies in composition suggesting it is involved in confering substrate specificity.

438753:AZC RS09700
gene id: 438753:AZC_RS09700
uniprot id: A8I2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS09590
gene id: 438753:AZC_RS09590
uniprot id: A8I2C3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

438753:AZC RS07595
gene id: 438753:AZC_RS07595
uniprot id: A8HX94
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS04590
gene id: 438753:AZC_RS04590
uniprot id: A8HU10
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS06070
gene id: 438753:AZC_RS06070
uniprot id: A8HRF7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS20910
gene id: 438753:AZC_RS20910
uniprot id: A8HRQ2
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS22145
gene id: 438753:AZC_RS22145
uniprot id: A8HVI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

438753:AZC RS19885
gene id: 438753:AZC_RS19885
uniprot id: A8IK87
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS19225
gene id: 438753:AZC_RS19225
uniprot id: A8INB9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS06875
gene id: 438753:AZC_RS06875
uniprot id: A8I156
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS19125
gene id: 438753:AZC_RS19125
uniprot id: A8IN72
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

438753:AZC RS00390
gene id: 438753:AZC_RS00390
uniprot id: A8IGE3
names: Similarity
messages: Belongs to the malate synthase family.

438753:AZC RS10610
gene id: 438753:AZC_RS10610
uniprot id: A8I6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS04020
gene id: 438753:AZC_RS04020
uniprot id: A8IQI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

438753:AZC RS14605
gene id: 438753:AZC_RS14605
uniprot id: A8I9R8
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

438753:AZC RS04545
gene id: 438753:AZC_RS04545
uniprot id: A8HTY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

438753:AZC RS19845
gene id: 438753:AZC_RS19845
uniprot id: A8IK65
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

438753:AZC RS03960
gene id: 438753:AZC_RS03960
uniprot id: A8IQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS03935
gene id: 438753:AZC_RS03935
uniprot id: A8IQE2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

438753:AZC RS13125
gene id: 438753:AZC_RS13125
uniprot id: A8IAP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

438753:AZC RS09010
gene id: 438753:AZC_RS09010
uniprot id: A8I4J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

438753:AZC RS15795
gene id: 438753:AZC_RS15795
uniprot id: A8IBF3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

438753:AZC RS17205
gene id: 438753:AZC_RS17205
uniprot id: A8IHZ6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

438753:AZC RS10775
gene id: 438753:AZC_RS10775
uniprot id: A8I755
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

438753:AZC RS19335
gene id: 438753:AZC_RS19335
uniprot id: A8INH8
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

438753:AZC RS19875
gene id: 438753:AZC_RS19875
uniprot id: A8IK81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS01015
gene id: 438753:AZC_RS01015
uniprot id: A8IHB7
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

438753:AZC RS00640
gene id: 438753:AZC_RS00640
uniprot id: A8IGS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS03890
gene id: 438753:AZC_RS03890
uniprot id: A8IQA7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS21810
gene id: 438753:AZC_RS21810
uniprot id: A8HT31
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

438753:AZC RS12395
gene id: 438753:AZC_RS12395
uniprot id: A8I6D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

438753:AZC RS15365
gene id: 438753:AZC_RS15365
uniprot id: A8IDP9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

438753:AZC RS15035
gene id: 438753:AZC_RS15035
uniprot id: A8IDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS09600
gene id: 438753:AZC_RS09600
uniprot id: A8I2C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

438753:AZC RS22820
gene id: 438753:AZC_RS22820
uniprot id: A8HWM7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

438753:AZC RS26285
gene id: 438753:AZC_RS26285
uniprot id: A8I9S8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

438753:AZC RS16975
gene id: 438753:AZC_RS16975
uniprot id: A8IHM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

438753:AZC RS10545
gene id: 438753:AZC_RS10545
uniprot id: A8I6R8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

438753:AZC RS02505
gene id: 438753:AZC_RS02505
uniprot id: A8IM57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

438753:AZC RS11555
gene id: 438753:AZC_RS11555
uniprot id: A8I8B2
names: Similarity
messages: Belongs to the BolA/IbaG family.

438753:AZC RS13195
gene id: 438753:AZC_RS13195
uniprot id: A8IAS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

438753:AZC RS03300
gene id: 438753:AZC_RS03300
uniprot id: A8IPL6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

438753:AZC RS06450
gene id: 438753:AZC_RS06450
uniprot id: A8I0F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

438753:AZC RS03020
gene id: 438753:AZC_RS03020
uniprot id: A8IMR1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

438753:AZC RS00720
gene id: 438753:AZC_RS00720
uniprot id: A8IGW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

438753:AZC RS10385
gene id: 438753:AZC_RS10385
uniprot id: A8I3B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

438753:AZC RS14430
gene id: 438753:AZC_RS14430
uniprot id: A8I9H6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS11880
gene id: 438753:AZC_RS11880
uniprot id: A8I5L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

438753:AZC RS12080
gene id: 438753:AZC_RS12080
uniprot id: A8I5X3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

438753:AZC RS16405
gene id: 438753:AZC_RS16405
uniprot id: A8ICA2
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

438753:AZC RS13280
gene id: 438753:AZC_RS13280
uniprot id: A8IAW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

438753:AZC RS07495
gene id: 438753:AZC_RS07495
uniprot id: A8HX32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

438753:AZC RS10140
gene id: 438753:AZC_RS10140
uniprot id: A8I2Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS00600
gene id: 438753:AZC_RS00600
uniprot id: A8IGQ7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

438753:AZC RS12600
gene id: 438753:AZC_RS12600
uniprot id: A8I6P3
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS11540
gene id: 438753:AZC_RS11540
uniprot id: A8I8A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

438753:AZC RS23835
gene id: 438753:AZC_RS23835
uniprot id: P26488
names: Function
names: Induction
messages: FixK is a protein that regulates nitrogen fixation genes both positively and negatively. FixK is a positive regulator of NifA expression. FixK may bind DNA at the FNR consensus binding site.
messages: Oxygen is involved in the regulation of fixK expression. FixLJ strongly controls the transcription of fixK.

438753:AZC RS12755
gene id: 438753:AZC_RS12755
uniprot id: A8IA52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS12770
gene id: 438753:AZC_RS12770
uniprot id: A8IA61
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

438753:AZC RS12250
gene id: 438753:AZC_RS12250
uniprot id: A8I661
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

438753:AZC RS12710
gene id: 438753:AZC_RS12710
uniprot id: A8IA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS08010
gene id: 438753:AZC_RS08010
uniprot id: A8HXX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS04820
gene id: 438753:AZC_RS04820
uniprot id: A8HUG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

438753:AZC RS20900
gene id: 438753:AZC_RS20900
uniprot id: A8HRP8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS22040
gene id: 438753:AZC_RS22040
uniprot id: A8HVB2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

438753:AZC RS22155
gene id: 438753:AZC_RS22155
uniprot id: A8HVI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

438753:AZC RS10935
gene id: 438753:AZC_RS10935
uniprot id: A8I7E6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS13810
gene id: 438753:AZC_RS13810
uniprot id: A8I8J6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS00420
gene id: 438753:AZC_RS00420
uniprot id: A8IGG0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS19330
gene id: 438753:AZC_RS19330
uniprot id: A8INH5
names: Similarity
messages: Belongs to the IlvD/Edd family.

438753:AZC RS14710
gene id: 438753:AZC_RS14710
uniprot id: A8I9X6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

438753:AZC RS15205
gene id: 438753:AZC_RS15205
uniprot id: A8IDH8
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS10190
gene id: 438753:AZC_RS10190
uniprot id: A8I308
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

438753:AZC RS11595
gene id: 438753:AZC_RS11595
uniprot id: A8I581
names: Similarity
messages: Belongs to the peptidase M16 family.

438753:AZC RS20380
gene id: 438753:AZC_RS20380
uniprot id: A8IL04
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

438753:AZC RS01945
gene id: 438753:AZC_RS01945
uniprot id: A8IJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

438753:AZC RS00110
gene id: 438753:AZC_RS00110
uniprot id: A8IG22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

438753:AZC RS06215
gene id: 438753:AZC_RS06215
uniprot id: A8HRL4
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS12510
gene id: 438753:AZC_RS12510
uniprot id: A8I6K0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

438753:AZC RS06770
gene id: 438753:AZC_RS06770
uniprot id: A8I100
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

438753:AZC RS10600
gene id: 438753:AZC_RS10600
uniprot id: A8I6U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS01630
gene id: 438753:AZC_RS01630
uniprot id: A8IJK5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

438753:AZC RS15475
gene id: 438753:AZC_RS15475
uniprot id: A8IDU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS07440
gene id: 438753:AZC_RS07440
uniprot id: A8HWZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS20285
gene id: 438753:AZC_RS20285
uniprot id: A8IKV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

438753:AZC RS15920
gene id: 438753:AZC_RS15920
uniprot id: Q04848
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
messages: Phosphorylated and dephosphorylated by NtrB.

438753:AZC RS09025
gene id: 438753:AZC_RS09025
uniprot id: A8I4K0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

438753:AZC RS18765
gene id: 438753:AZC_RS18765
uniprot id: A8IFR3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

438753:AZC RS00065
gene id: 438753:AZC_RS00065
uniprot id: A8IG09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

438753:AZC RS12170
gene id: 438753:AZC_RS12170
uniprot id: A8I621
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS21270
gene id: 438753:AZC_RS21270
uniprot id: A8HS70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

438753:AZC RS23370
gene id: 438753:AZC_RS23370
uniprot id: A8HZA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

438753:AZC RS19895
gene id: 438753:AZC_RS19895
uniprot id: A8IK92
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

438753:AZC RS08610
gene id: 438753:AZC_RS08610
uniprot id: A8I3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS15755
gene id: 438753:AZC_RS15755
uniprot id: A8IBD4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

438753:AZC RS02480
gene id: 438753:AZC_RS02480
uniprot id: A8IM50
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

438753:AZC RS13135
gene id: 438753:AZC_RS13135
uniprot id: A8IAQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

438753:AZC RS11515
gene id: 438753:AZC_RS11515
uniprot id: A8I889
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

438753:AZC RS23410
gene id: 438753:AZC_RS23410
uniprot id: A8HZC9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

438753:AZC RS18745
gene id: 438753:AZC_RS18745
uniprot id: A8IFQ0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

438753:AZC RS09560
gene id: 438753:AZC_RS09560
uniprot id: A8I2B2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS09325
gene id: 438753:AZC_RS09325
uniprot id: A8I518
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS15900
gene id: 438753:AZC_RS15900
uniprot id: Q04856
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of a potassium transport system.
messages: The RCK N-terminal domain binds NAD and possibly other effectors. This is expected to cause a conformation change that regulates potassium transport (By similarity).

438753:AZC RS10315
gene id: 438753:AZC_RS10315
uniprot id: A8I378
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS05315
gene id: 438753:AZC_RS05315
uniprot id: A8HQH7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

438753:AZC RS14760
gene id: 438753:AZC_RS14760
uniprot id: A8ICW8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

438753:AZC RS10380
gene id: 438753:AZC_RS10380
uniprot id: A8I3B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

438753:AZC RS03090
gene id: 438753:AZC_RS03090
uniprot id: A8IMU4
names: Similarity
messages: Belongs to the HupF/HypC family.

438753:AZC RS09340
gene id: 438753:AZC_RS09340
uniprot id: A8I525
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

438753:AZC RS14965
gene id: 438753:AZC_RS14965
uniprot id: A8ID88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

438753:AZC RS07425
gene id: 438753:AZC_RS07425
uniprot id: A8HWY7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

438753:AZC RS05425
gene id: 438753:AZC_RS05425
uniprot id: A8HQS6
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS13190
gene id: 438753:AZC_RS13190
uniprot id: A8IAR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

438753:AZC RS10865
gene id: 438753:AZC_RS10865
uniprot id: A8I7A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Membrane

438753:AZC RS09575
gene id: 438753:AZC_RS09575
uniprot id: A8I2B7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

438753:AZC RS05950
gene id: 438753:AZC_RS05950
uniprot id: A8HRA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

438753:AZC RS08715
gene id: 438753:AZC_RS08715
uniprot id: A8I416
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS23910
gene id: 438753:AZC_RS23910
uniprot id: A8I052
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

438753:AZC RS03895
gene id: 438753:AZC_RS03895
uniprot id: A8IQB2
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

438753:AZC RS23395
gene id: 438753:AZC_RS23395
uniprot id: A8HZC1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

438753:AZC RS13115
gene id: 438753:AZC_RS13115
uniprot id: A8IAP5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

438753:AZC RS05900
gene id: 438753:AZC_RS05900
uniprot id: A8HR98
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS21610
gene id: 438753:AZC_RS21610
uniprot id: A8HSR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

438753:AZC RS20975
gene id: 438753:AZC_RS20975
uniprot id: A8HRT0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

438753:AZC RS03270
gene id: 438753:AZC_RS03270
uniprot id: A8IPK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

438753:AZC RS03525
gene id: 438753:AZC_RS03525
uniprot id: A8IPT0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

438753:AZC RS01685
gene id: 438753:AZC_RS01685
uniprot id: A8IJN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

438753:AZC RS09155
gene id: 438753:AZC_RS09155
uniprot id: A8I4R8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

438753:AZC RS20695
gene id: 438753:AZC_RS20695
uniprot id: A8ILH7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

438753:AZC RS02805
gene id: 438753:AZC_RS02805
uniprot id: A8IMH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

438753:AZC RS13815
gene id: 438753:AZC_RS13815
uniprot id: A8I8J9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS16070
gene id: 438753:AZC_RS16070
uniprot id: A8IBT1
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS00820
gene id: 438753:AZC_RS00820
uniprot id: A8IH20
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

438753:AZC RS24030
gene id: 438753:AZC_RS24030
uniprot id: A8I220
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

438753:AZC RS15950
gene id: 438753:AZC_RS15950
uniprot id: A8IBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

438753:AZC RS23025
gene id: 438753:AZC_RS23025
uniprot id: A8HYR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

438753:AZC RS01415
gene id: 438753:AZC_RS01415
uniprot id: A8IJB4
names: Similarity
messages: Belongs to the peptidase C40 family.

438753:AZC RS05250
gene id: 438753:AZC_RS05250
uniprot id: A8HQ98
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

438753:AZC RS00155
gene id: 438753:AZC_RS00155
uniprot id: A8IG34
names: Similarity
messages: Belongs to the thioesterase PaaI family.

438753:AZC RS07430
gene id: 438753:AZC_RS07430
uniprot id: A8HWZ0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

438753:AZC RS01555
gene id: 438753:AZC_RS01555
uniprot id: A8IJH6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

438753:AZC RS09090
gene id: 438753:AZC_RS09090
uniprot id: A8I4P0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

438753:AZC RS05215
gene id: 438753:AZC_RS05215
uniprot id: A8HQ47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

438753:AZC RS10580
gene id: 438753:AZC_RS10580
uniprot id: A8I6T7
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS13700
gene id: 438753:AZC_RS13700
uniprot id: A8I8D3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

438753:AZC RS15810
gene id: 438753:AZC_RS15810
uniprot id: A8IBG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

438753:AZC RS04025
gene id: 438753:AZC_RS04025
uniprot id: A8IQJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

438753:AZC RS06985
gene id: 438753:AZC_RS06985
uniprot id: A8I1C0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

438753:AZC RS11660
gene id: 438753:AZC_RS11660
uniprot id: A8I5B0
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

438753:AZC RS02580
gene id: 438753:AZC_RS02580
uniprot id: A8IM87
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

438753:AZC RS17575
gene id: 438753:AZC_RS17575
uniprot id: A8IIK0
names: Similarity
messages: Belongs to the HesB/IscA family.

438753:AZC RS01030
gene id: 438753:AZC_RS01030
uniprot id: A8IIW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS14695
gene id: 438753:AZC_RS14695
uniprot id: A8I9W7
names: Similarity
messages: Belongs to the UPF0173 family.

438753:AZC RS20970
gene id: 438753:AZC_RS20970
uniprot id: A8HRS7
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

438753:AZC RS23670
gene id: 438753:AZC_RS23670
uniprot id: A8HZS8
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS03615
gene id: 438753:AZC_RS03615
uniprot id: A8IPW5
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

438753:AZC RS13915
gene id: 438753:AZC_RS13915
uniprot id: A8I8Q1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

438753:AZC RS19820
gene id: 438753:AZC_RS19820
uniprot id: A8IPD3
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

438753:AZC RS11985
gene id: 438753:AZC_RS11985
uniprot id: A8I5S8
names: Similarity
messages: Belongs to the acylphosphatase family.

438753:AZC RS02850
gene id: 438753:AZC_RS02850
uniprot id: A8IMJ0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

438753:AZC RS20655
gene id: 438753:AZC_RS20655
uniprot id: A8ILF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

438753:AZC RS06495
gene id: 438753:AZC_RS06495
uniprot id: A8I0I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

438753:AZC RS11675
gene id: 438753:AZC_RS11675
uniprot id: A8I5B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

438753:AZC RS19150
gene id: 438753:AZC_RS19150
uniprot id: A8IN85
names: Similarity
messages: Belongs to the peptidase S49 family.

438753:AZC RS17740
gene id: 438753:AZC_RS17740
uniprot id: P26484
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from FixA/FixB and reduces a quinone.

438753:AZC RS19850
gene id: 438753:AZC_RS19850
uniprot id: A8IK67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

438753:AZC RS11345
gene id: 438753:AZC_RS11345
uniprot id: A8I7Z9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

438753:AZC RS03235
gene id: 438753:AZC_RS03235
uniprot id: A8IPJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

438753:AZC RS03385
gene id: 438753:AZC_RS03385
uniprot id: A8IPP4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

438753:AZC RS05245
gene id: 438753:AZC_RS05245
uniprot id: A8HQ90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

438753:AZC RS11580
gene id: 438753:AZC_RS11580
uniprot id: A8I574
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

438753:AZC RS24015
gene id: 438753:AZC_RS24015
uniprot id: A8I209
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

438753:AZC RS07795
gene id: 438753:AZC_RS07795
uniprot id: A8HXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS16220
gene id: 438753:AZC_RS16220
uniprot id: A8IC06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

438753:AZC RS00470
gene id: 438753:AZC_RS00470
uniprot id: A8IGI8
names: Similarity
messages: Belongs to the Gfa family.

438753:AZC RS20520
gene id: 438753:AZC_RS20520
uniprot id: A8IL81
names: Similarity
messages: Belongs to the UPF0178 family.

438753:AZC RS12045
gene id: 438753:AZC_RS12045
uniprot id: A8I5V8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

438753:AZC RS04915
gene id: 438753:AZC_RS04915
uniprot id: A8HUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

438753:AZC RS05320
gene id: 438753:AZC_RS05320
uniprot id: A8HQI2
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

438753:AZC RS07665
gene id: 438753:AZC_RS07665
uniprot id: A8HXD7
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS16780
gene id: 438753:AZC_RS16780
uniprot id: A8IHC7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

438753:AZC RS13180
gene id: 438753:AZC_RS13180
uniprot id: A8IAR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

438753:AZC RS11945
gene id: 438753:AZC_RS11945
uniprot id: A8I5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

438753:AZC RS10245
gene id: 438753:AZC_RS10245
uniprot id: A8I332
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS11390
gene id: 438753:AZC_RS11390
uniprot id: A8I819
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

438753:AZC RS15565
gene id: 438753:AZC_RS15565
uniprot id: A8IDZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

438753:AZC RS22990
gene id: 438753:AZC_RS22990
uniprot id: A8HYP1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

438753:AZC RS15055
gene id: 438753:AZC_RS15055
uniprot id: A8IDC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS05380
gene id: 438753:AZC_RS05380
uniprot id: A8HQP5
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

438753:AZC RS09215
gene id: 438753:AZC_RS09215
uniprot id: A8I4V1
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

438753:AZC RS16285
gene id: 438753:AZC_RS16285
uniprot id: A8IC39
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

438753:AZC RS24255
gene id: 438753:AZC_RS24255
uniprot id: A8HTM3
names: Similarity
messages: Belongs to the virb1 family.

438753:AZC RS15535
gene id: 438753:AZC_RS15535
uniprot id: A8IDX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

438753:AZC RS04710
gene id: 438753:AZC_RS04710
uniprot id: A8HU86
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

438753:AZC RS07420
gene id: 438753:AZC_RS07420
uniprot id: A8HWY4
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

438753:AZC RS02070
gene id: 438753:AZC_RS02070
uniprot id: A8IK62
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

438753:AZC RS01600
gene id: 438753:AZC_RS01600
uniprot id: A8IJJ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

438753:AZC RS19970
gene id: 438753:AZC_RS19970
uniprot id: A8IKD2
names: Activity Regulation
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclic amide hydrolase (CyAH) family.
messages: Homotetramer.
messages: Inhibited by barbituric acid.
messages: Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine. Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret.
messages: The monomer structure is formed from three repeating units (RUs) that share the same structure as one another. The monomer, the active site and substrate all possess threefold rotational symmetry, to the extent that the active site possesses three potential Ser-Lys catalytic dyads. It is possible that any or all of the three active-site serines may act as nucleophile (albeit only one can do so per catalytic cycle). Mutant, bioinformatic and structural data propose one specific dyad being involved in catalysis.

438753:AZC RS13935
gene id: 438753:AZC_RS13935
uniprot id: A8I8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS20645
gene id: 438753:AZC_RS20645
uniprot id: A8ILF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

438753:AZC RS03565
gene id: 438753:AZC_RS03565
uniprot id: A8IPU5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS18085
gene id: 438753:AZC_RS18085
uniprot id: A8IEP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS15420
gene id: 438753:AZC_RS15420
uniprot id: A8IDS3
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

438753:AZC RS01575
gene id: 438753:AZC_RS01575
uniprot id: A8IJI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

438753:AZC RS18490
gene id: 438753:AZC_RS18490
uniprot id: A8IF82
names: Similarity
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.

438753:AZC RS11455
gene id: 438753:AZC_RS11455
uniprot id: A8I855
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

438753:AZC RS21455
gene id: 438753:AZC_RS21455
uniprot id: A8HSH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

438753:AZC RS13120
gene id: 438753:AZC_RS13120
uniprot id: A8IAP6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

438753:AZC RS01660
gene id: 438753:AZC_RS01660
uniprot id: A8IJL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

438753:AZC RS00085
gene id: 438753:AZC_RS00085
uniprot id: A8IG15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS15710
gene id: 438753:AZC_RS15710
uniprot id: A8IE70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS20895
gene id: 438753:AZC_RS20895
uniprot id: A8HRP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

438753:AZC RS01255
gene id: 438753:AZC_RS01255
uniprot id: A8IJ44
names: Similarity
messages: Belongs to the GST superfamily.

438753:AZC RS14155
gene id: 438753:AZC_RS14155
uniprot id: A8I931
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

438753:AZC RS06010
gene id: 438753:AZC_RS06010
uniprot id: A8HRD2
names: Similarity
messages: Belongs to the PRORSD1 family.

438753:AZC RS08015
gene id: 438753:AZC_RS08015
uniprot id: A8HXX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS09135
gene id: 438753:AZC_RS09135
uniprot id: A8I4Q6
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS08960
gene id: 438753:AZC_RS08960
uniprot id: A8I4G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

438753:AZC RS07860
gene id: 438753:AZC_RS07860
uniprot id: A8HXP3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

438753:AZC RS00695
gene id: 438753:AZC_RS00695
uniprot id: A8IGV6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

438753:AZC RS09965
gene id: 438753:AZC_RS09965
uniprot id: A8I2R8
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

438753:AZC RS21165
gene id: 438753:AZC_RS21165
uniprot id: A8HS15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

438753:AZC RS06740
gene id: 438753:AZC_RS06740
uniprot id: A8I0Y3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS13625
gene id: 438753:AZC_RS13625
uniprot id: A8IBA5
names: Similarity
messages: Belongs to the amidase family.

438753:AZC RS20070
gene id: 438753:AZC_RS20070
uniprot id: A8IKI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

438753:AZC RS14185
gene id: 438753:AZC_RS14185
uniprot id: A8I947
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

438753:AZC RS10410
gene id: 438753:AZC_RS10410
uniprot id: A8I3C7
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS12035
gene id: 438753:AZC_RS12035
uniprot id: A8I5V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

438753:AZC RS14705
gene id: 438753:AZC_RS14705
uniprot id: A8I9X4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

438753:AZC RS18155
gene id: 438753:AZC_RS18155
uniprot id: A8IES7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

438753:AZC RS08925
gene id: 438753:AZC_RS08925
uniprot id: A8I4E3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

438753:AZC RS16135
gene id: 438753:AZC_RS16135
uniprot id: A8IBW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

438753:AZC RS02965
gene id: 438753:AZC_RS02965
uniprot id: A8IMN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS20205
gene id: 438753:AZC_RS20205
uniprot id: A8IKQ1
names: Similarity
messages: Belongs to the CobH/CbiC family.

438753:AZC RS06725
gene id: 438753:AZC_RS06725
uniprot id: A8I0X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell inner membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

438753:AZC RS07560
gene id: 438753:AZC_RS07560
uniprot id: A8HX72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

438753:AZC RS04005
gene id: 438753:AZC_RS04005
uniprot id: A8IQH9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS14650
gene id: 438753:AZC_RS14650
uniprot id: A8I9U5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

438753:AZC RS21585
gene id: 438753:AZC_RS21585
uniprot id: A8HSP7
names: Similarity
messages: Belongs to the UPF0758 family.

438753:AZC RS17025
gene id: 438753:AZC_RS17025
uniprot id: A8IHP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS08750
gene id: 438753:AZC_RS08750
uniprot id: A8I438
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

438753:AZC RS19615
gene id: 438753:AZC_RS19615
uniprot id: Q07759
names: Function
names: Similarity
messages: Belongs to the NodU/CmcH family.
messages: Involved in 6-O-carbamoylation of Nod-factors.

438753:AZC RS20190
gene id: 438753:AZC_RS20190
uniprot id: A8IKP2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

438753:AZC RS05420
gene id: 438753:AZC_RS05420
uniprot id: A8HQS3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS11490
gene id: 438753:AZC_RS11490
uniprot id: A8I875
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

438753:AZC RS21285
gene id: 438753:AZC_RS21285
uniprot id: A8HS75
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

438753:AZC RS22025
gene id: 438753:AZC_RS22025
uniprot id: A8HVA4
names: Similarity
messages: Belongs to the FrmR/RcnR family.

438753:AZC RS04550
gene id: 438753:AZC_RS04550
uniprot id: A8HTY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

438753:AZC RS00525
gene id: 438753:AZC_RS00525
uniprot id: A8IGL5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

438753:AZC RS00125
gene id: 438753:AZC_RS00125
uniprot id: A8IG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS13320
gene id: 438753:AZC_RS13320
uniprot id: A8IAX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

438753:AZC RS23245
gene id: 438753:AZC_RS23245
uniprot id: A8HZ44
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

438753:AZC RS09040
gene id: 438753:AZC_RS09040
uniprot id: A8I4L0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

438753:AZC RS12545
gene id: 438753:AZC_RS12545
uniprot id: A8I6L7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

438753:AZC RS21235
gene id: 438753:AZC_RS21235
uniprot id: A8HS51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

438753:AZC RS14725
gene id: 438753:AZC_RS14725
uniprot id: A8ICV0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

438753:AZC RS09385
gene id: 438753:AZC_RS09385
uniprot id: A8I540
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

438753:AZC RS00105
gene id: 438753:AZC_RS00105
uniprot id: A8IG20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

438753:AZC RS09015
gene id: 438753:AZC_RS09015
uniprot id: A8I4J4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

438753:AZC RS04755
gene id: 438753:AZC_RS04755
uniprot id: A8HUB5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

438753:AZC RS21465
gene id: 438753:AZC_RS21465
uniprot id: A8HSI3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

438753:AZC RS03955
gene id: 438753:AZC_RS03955
uniprot id: A8IQF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS15935
gene id: 438753:AZC_RS15935
uniprot id: A8IBL6
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

438753:AZC RS11465
gene id: 438753:AZC_RS11465
uniprot id: A8I860
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS09055
gene id: 438753:AZC_RS09055
uniprot id: A8I4L8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

438753:AZC RS20510
gene id: 438753:AZC_RS20510
uniprot id: A8IL76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

438753:AZC RS12260
gene id: 438753:AZC_RS12260
uniprot id: A8I664
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

438753:AZC RS19235
gene id: 438753:AZC_RS19235
uniprot id: A8INC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

438753:AZC RS22095
gene id: 438753:AZC_RS22095
uniprot id: A8HVF1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

438753:AZC RS16860
gene id: 438753:AZC_RS16860
uniprot id: A8IHG4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS01105
gene id: 438753:AZC_RS01105
uniprot id: A8IIY5
names: Similarity
messages: Belongs to the peptidase M24B family.

438753:AZC RS00035
gene id: 438753:AZC_RS00035
uniprot id: A8IFZ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

438753:AZC RS14085
gene id: 438753:AZC_RS14085
uniprot id: A8I8Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS20980
gene id: 438753:AZC_RS20980
uniprot id: A8HRT1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

438753:AZC RS08700
gene id: 438753:AZC_RS08700
uniprot id: A8I407
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

438753:AZC RS16600
gene id: 438753:AZC_RS16600
uniprot id: A8ICK2
names: Subcellular Location Annotation
messages: Periplasm

438753:AZC RS22340
gene id: 438753:AZC_RS22340
uniprot id: A8HVU0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS09615
gene id: 438753:AZC_RS09615
uniprot id: A8I2D3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

438753:AZC RS11535
gene id: 438753:AZC_RS11535
uniprot id: A8I8A0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

438753:AZC RS02440
gene id: 438753:AZC_RS02440
uniprot id: A8IM38
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS13130
gene id: 438753:AZC_RS13130
uniprot id: A8IAP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

438753:AZC RS15955
gene id: 438753:AZC_RS15955
uniprot id: A8IBM6
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS10755
gene id: 438753:AZC_RS10755
uniprot id: A8I742
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

438753:AZC RS18645
gene id: 438753:AZC_RS18645
uniprot id: A8IFI2
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

438753:AZC RS03470
gene id: 438753:AZC_RS03470
uniprot id: A8IPR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

438753:AZC RS08850
gene id: 438753:AZC_RS08850
uniprot id: A8I497
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

438753:AZC RS19990
gene id: 438753:AZC_RS19990
uniprot id: A8IKE2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS00300
gene id: 438753:AZC_RS00300
uniprot id: A8IG96
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS09980
gene id: 438753:AZC_RS09980
uniprot id: A8I2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS21865
gene id: 438753:AZC_RS21865
uniprot id: A8HT64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

438753:AZC RS08710
gene id: 438753:AZC_RS08710
uniprot id: A8I413
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

438753:AZC RS15855
gene id: 438753:AZC_RS15855
uniprot id: A8IBI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

438753:AZC RS11725
gene id: 438753:AZC_RS11725
uniprot id: A8I5E1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

438753:AZC RS10170
gene id: 438753:AZC_RS10170
uniprot id: A8I300
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

438753:AZC RS07950
gene id: 438753:AZC_RS07950
uniprot id: A8HXU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

438753:AZC RS04055
gene id: 438753:AZC_RS04055
uniprot id: A8IQL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

438753:AZC RS09005
gene id: 438753:AZC_RS09005
uniprot id: A8I4I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

438753:AZC RS03815
gene id: 438753:AZC_RS03815
uniprot id: A8IQ60
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

438753:AZC RS02705
gene id: 438753:AZC_RS02705
uniprot id: A8IMD7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

438753:AZC RS22135
gene id: 438753:AZC_RS22135
uniprot id: A8HVH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

438753:AZC RS15010
gene id: 438753:AZC_RS15010
uniprot id: A8IDA9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

438753:AZC RS01525
gene id: 438753:AZC_RS01525
uniprot id: A8IJG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

438753:AZC RS11450
gene id: 438753:AZC_RS11450
uniprot id: A8I852
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS07460
gene id: 438753:AZC_RS07460
uniprot id: A8HX09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS14935
gene id: 438753:AZC_RS14935
uniprot id: A8ID68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

438753:AZC RS21850
gene id: 438753:AZC_RS21850
uniprot id: A8HT54
names: Similarity
messages: Belongs to the thioredoxin family.

438753:AZC RS15825
gene id: 438753:AZC_RS15825
uniprot id: A8IBG6
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

438753:AZC RS03370
gene id: 438753:AZC_RS03370
uniprot id: A8IPN9
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

438753:AZC RS01905
gene id: 438753:AZC_RS01905
uniprot id: A8IJX4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

438753:AZC RS08305
gene id: 438753:AZC_RS08305
uniprot id: A8HYD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

438753:AZC RS07105
gene id: 438753:AZC_RS07105
uniprot id: A8I1I3
names: Function
messages: Multidrug efflux pump.

438753:AZC RS00425
gene id: 438753:AZC_RS00425
uniprot id: A8IGG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

438753:AZC RS13090
gene id: 438753:AZC_RS13090
uniprot id: A8IAN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

438753:AZC RS08300
gene id: 438753:AZC_RS08300
uniprot id: P94126
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.
messages: The activity of this enzyme could be controlled by adenylation under conditions of abundant glutamine.

438753:AZC RS01075
gene id: 438753:AZC_RS01075
uniprot id: A8IIX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

438753:AZC RS19160
gene id: 438753:AZC_RS19160
uniprot id: A8IN91
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

438753:AZC RS16195
gene id: 438753:AZC_RS16195
uniprot id: A8IBZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

438753:AZC RS20535
gene id: 438753:AZC_RS20535
uniprot id: A8IL89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

438753:AZC RS11695
gene id: 438753:AZC_RS11695
uniprot id: A8I5C6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

438753:AZC RS18850
gene id: 438753:AZC_RS18850
uniprot id: A8IFX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

438753:AZC RS04995
gene id: 438753:AZC_RS04995
uniprot id: A8HUR7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

438753:AZC RS17680
gene id: 438753:AZC_RS17680
uniprot id: A8IIQ6
names: Similarity
messages: Belongs to the BolA/IbaG family.

438753:AZC RS12500
gene id: 438753:AZC_RS12500
uniprot id: A8I6J5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

438753:AZC RS16855
gene id: 438753:AZC_RS16855
uniprot id: A8IHG2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

438753:AZC RS02270
gene id: 438753:AZC_RS02270
uniprot id: A8ILY5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

438753:AZC RS10335
gene id: 438753:AZC_RS10335
uniprot id: A8I389
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS03060
gene id: 438753:AZC_RS03060
uniprot id: A8IMS9
names: Similarity
messages: Belongs to the HupH/HyaF family.

438753:AZC RS22350
gene id: 438753:AZC_RS22350
uniprot id: A8HVU6
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS17705
gene id: 438753:AZC_RS17705
uniprot id: A8IIS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS03290
gene id: 438753:AZC_RS03290
uniprot id: A8IPL3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

438753:AZC RS19020
gene id: 438753:AZC_RS19020
uniprot id: A8IN21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

438753:AZC RS05820
gene id: 438753:AZC_RS05820
uniprot id: A8HR74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS02590
gene id: 438753:AZC_RS02590
uniprot id: A8IM90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

438753:AZC RS20370
gene id: 438753:AZC_RS20370
uniprot id: A8IKZ8
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS12900
gene id: 438753:AZC_RS12900
uniprot id: A8IAD2
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.

438753:AZC RS07410
gene id: 438753:AZC_RS07410
uniprot id: A8HWX9
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS18935
gene id: 438753:AZC_RS18935
uniprot id: A8IMY0
names: Similarity
messages: Belongs to the BolA/IbaG family.

438753:AZC RS01475
gene id: 438753:AZC_RS01475
uniprot id: A8IJE1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS11290
gene id: 438753:AZC_RS11290
uniprot id: A8I7X7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

438753:AZC RS01545
gene id: 438753:AZC_RS01545
uniprot id: A8IJH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

438753:AZC RS23560
gene id: 438753:AZC_RS23560
uniprot id: A8HZL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

438753:AZC RS09175
gene id: 438753:AZC_RS09175
uniprot id: A8I4T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

438753:AZC RS23525
gene id: 438753:AZC_RS23525
uniprot id: A8HZK2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

438753:AZC RS10205
gene id: 438753:AZC_RS10205
uniprot id: A8I315
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS00740
gene id: 438753:AZC_RS00740
uniprot id: A8IGX6
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS22905
gene id: 438753:AZC_RS22905
uniprot id: A8HWT2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

438753:AZC RS02190
gene id: 438753:AZC_RS02190
uniprot id: A8ILW2
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

438753:AZC RS00015
gene id: 438753:AZC_RS00015
uniprot id: A8IFY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

438753:AZC RS20180
gene id: 438753:AZC_RS20180
uniprot id: A8IKN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

438753:AZC RS23155
gene id: 438753:AZC_RS23155
uniprot id: A8HYZ4
names: Similarity
messages: Belongs to the pirin family.

438753:AZC RS13895
gene id: 438753:AZC_RS13895
uniprot id: A8I8N9
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

438753:AZC RS03230
gene id: 438753:AZC_RS03230
uniprot id: A8IPJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

438753:AZC RS03015
gene id: 438753:AZC_RS03015
uniprot id: A8IMQ9
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

438753:AZC RS19950
gene id: 438753:AZC_RS19950
uniprot id: A8IKC2
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS10200
gene id: 438753:AZC_RS10200
uniprot id: A8I312
names: Function
names: Similarity
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).

438753:AZC RS22195
gene id: 438753:AZC_RS22195
uniprot id: A8HVL5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

438753:AZC RS17950
gene id: 438753:AZC_RS17950
uniprot id: A8IEH2
names: Similarity
messages: Belongs to the pyruvate kinase family.

438753:AZC RS20990
gene id: 438753:AZC_RS20990
uniprot id: A8HRT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

438753:AZC RS10925
gene id: 438753:AZC_RS10925
uniprot id: A8I7E0
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS19405
gene id: 438753:AZC_RS19405
uniprot id: A8INM5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS19840
gene id: 438753:AZC_RS19840
uniprot id: A8IPE4
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS08740
gene id: 438753:AZC_RS08740
uniprot id: A8I432
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

438753:AZC RS02680
gene id: 438753:AZC_RS02680
uniprot id: A8IMC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS08790
gene id: 438753:AZC_RS08790
uniprot id: A8I464
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

438753:AZC RS24090
gene id: 438753:AZC_RS24090
uniprot id: A8I246
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

438753:AZC RS06465
gene id: 438753:AZC_RS06465
uniprot id: A8I0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

438753:AZC RS09775
gene id: 438753:AZC_RS09775
uniprot id: A8I2J4
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS21425
gene id: 438753:AZC_RS21425
uniprot id: A8HSF5
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

438753:AZC RS02950
gene id: 438753:AZC_RS02950
uniprot id: A8IMM8
names: Similarity
messages: Belongs to the GbsR family.

438753:AZC RS15585
gene id: 438753:AZC_RS15585
uniprot id: A8IE05
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

438753:AZC RS06525
gene id: 438753:AZC_RS06525
uniprot id: A8I0K3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

438753:AZC RS13945
gene id: 438753:AZC_RS13945
uniprot id: A8I8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS05095
gene id: 438753:AZC_RS05095
uniprot id: A8HUZ4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

438753:AZC RS04110
gene id: 438753:AZC_RS04110
uniprot id: A8IQP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

438753:AZC RS07300
gene id: 438753:AZC_RS07300
uniprot id: A8I1T7
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS05880
gene id: 438753:AZC_RS05880
uniprot id: A8HR92
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

438753:AZC RS23060
gene id: 438753:AZC_RS23060
uniprot id: A8HYT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

438753:AZC RS22485
gene id: 438753:AZC_RS22485
uniprot id: A8HW36
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

438753:AZC RS20630
gene id: 438753:AZC_RS20630
uniprot id: A8ILE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

438753:AZC RS22090
gene id: 438753:AZC_RS22090
uniprot id: A8HVE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

438753:AZC RS10615
gene id: 438753:AZC_RS10615
uniprot id: A8I6V7
names: Similarity
messages: Belongs to the histone deacetylase family.

438753:AZC RS22815
gene id: 438753:AZC_RS22815
uniprot id: A8HWM3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

438753:AZC RS07520
gene id: 438753:AZC_RS07520
uniprot id: A8HX46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

438753:AZC RS10835
gene id: 438753:AZC_RS10835
uniprot id: A8I789
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS14045
gene id: 438753:AZC_RS14045
uniprot id: A8I8X1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS16530
gene id: 438753:AZC_RS16530
uniprot id: A8ICG6
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS18595
gene id: 438753:AZC_RS18595
uniprot id: A8IFE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

438753:AZC RS04085
gene id: 438753:AZC_RS04085
uniprot id: A8IQN3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

438753:AZC RS18550
gene id: 438753:AZC_RS18550
uniprot id: A8IFC3
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

438753:AZC RS12240
gene id: 438753:AZC_RS12240
uniprot id: A8I655
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

438753:AZC RS20355
gene id: 438753:AZC_RS20355
uniprot id: A8IKZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

438753:AZC RS21340
gene id: 438753:AZC_RS21340
uniprot id: A8HSA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

438753:AZC RS22130
gene id: 438753:AZC_RS22130
uniprot id: A8HVH3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

438753:AZC RS11340
gene id: 438753:AZC_RS11340
uniprot id: A8I7Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

438753:AZC RS06835
gene id: 438753:AZC_RS06835
uniprot id: A8I135
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS04030
gene id: 438753:AZC_RS04030
uniprot id: A8IQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

438753:AZC RS15715
gene id: 438753:AZC_RS15715
uniprot id: A8IE72
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

438753:AZC RS13335
gene id: 438753:AZC_RS13335
uniprot id: A8IAY3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS05300
gene id: 438753:AZC_RS05300
uniprot id: A8HQG0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

438753:AZC RS07945
gene id: 438753:AZC_RS07945
uniprot id: A8HXT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

438753:AZC RS02400
gene id: 438753:AZC_RS02400
uniprot id: A8IM27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

438753:AZC RS06910
gene id: 438753:AZC_RS06910
uniprot id: A8I174
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

438753:AZC RS16075
gene id: 438753:AZC_RS16075
uniprot id: A8IBT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

438753:AZC RS05430
gene id: 438753:AZC_RS05430
uniprot id: A8HQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

438753:AZC RS04170
gene id: 438753:AZC_RS04170
uniprot id: A8HTB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS14390
gene id: 438753:AZC_RS14390
uniprot id: A8I9F4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS20250
gene id: 438753:AZC_RS20250
uniprot id: A8IKT0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

438753:AZC RS20625
gene id: 438753:AZC_RS20625
uniprot id: A8ILE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

438753:AZC RS10790
gene id: 438753:AZC_RS10790
uniprot id: A8I763
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

438753:AZC RS18695
gene id: 438753:AZC_RS18695
uniprot id: A8IFL5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

438753:AZC RS20635
gene id: 438753:AZC_RS20635
uniprot id: A8ILE6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

438753:AZC RS21710
gene id: 438753:AZC_RS21710
uniprot id: A8HSX4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

438753:AZC RS07635
gene id: 438753:AZC_RS07635
uniprot id: A8HXB9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

438753:AZC RS20915
gene id: 438753:AZC_RS20915
uniprot id: A8HRQ5
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS21700
gene id: 438753:AZC_RS21700
uniprot id: A8HSW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

438753:AZC RS08215
gene id: 438753:AZC_RS08215
uniprot id: A8HY78
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

438753:AZC RS14020
gene id: 438753:AZC_RS14020
uniprot id: A8I8V7
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

438753:AZC RS01375
gene id: 438753:AZC_RS01375
uniprot id: A8IJ97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

438753:AZC RS06165
gene id: 438753:AZC_RS06165
uniprot id: A8HRJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

438753:AZC RS00445
gene id: 438753:AZC_RS00445
uniprot id: A8IGH5
names: Similarity
messages: Belongs to the YkuD family.

438753:AZC RS21205
gene id: 438753:AZC_RS21205
uniprot id: A8HS37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

438753:AZC RS14215
gene id: 438753:AZC_RS14215
uniprot id: A8I965
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

438753:AZC RS11685
gene id: 438753:AZC_RS11685
uniprot id: A8I5C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

438753:AZC RS23005
gene id: 438753:AZC_RS23005
uniprot id: A8HYP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

438753:AZC RS12735
gene id: 438753:AZC_RS12735
uniprot id: A8IA41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS16595
gene id: 438753:AZC_RS16595
uniprot id: A8ICJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

438753:AZC RS19300
gene id: 438753:AZC_RS19300
uniprot id: A8INF8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

438753:AZC RS14835
gene id: 438753:AZC_RS14835
uniprot id: A8ID09
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS18335
gene id: 438753:AZC_RS18335
uniprot id: A8IF17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

438753:AZC RS14025
gene id: 438753:AZC_RS14025
uniprot id: A8I8W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

438753:AZC RS09050
gene id: 438753:AZC_RS09050
uniprot id: A8I4L5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

438753:AZC RS19625
gene id: 438753:AZC_RS19625
uniprot id: Q07755
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NodC/HAS family.
messages: Cell membrane
messages: Involved in the synthesis of Nod factor, a sulfated N-acyl-beta-1,4-tetrasaccharide of N-acetylglucosamine which initiates a series of events in the host plant species leading eventually to nodulation.

438753:AZC RS14885
gene id: 438753:AZC_RS14885
uniprot id: A8ID36
names: Subcellular Location Annotation
messages: Membrane

438753:AZC RS17245
gene id: 438753:AZC_RS17245
uniprot id: A8II17
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

438753:AZC RS12705
gene id: 438753:AZC_RS12705
uniprot id: A8IA25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS15525
gene id: 438753:AZC_RS15525
uniprot id: A8IDX3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

438753:AZC RS12205
gene id: 438753:AZC_RS12205
uniprot id: A8I638
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

438753:AZC RS18340
gene id: 438753:AZC_RS18340
uniprot id: A8IF20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

438753:AZC RS10145
gene id: 438753:AZC_RS10145
uniprot id: A8I2Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

438753:AZC RS09390
gene id: 438753:AZC_RS09390
uniprot id: A8I541
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

438753:AZC RS08340
gene id: 438753:AZC_RS08340
uniprot id: A8HYF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

438753:AZC RS23130
gene id: 438753:AZC_RS23130
uniprot id: A8HYY0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

438753:AZC RS09975
gene id: 438753:AZC_RS09975
uniprot id: A8I2S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

438753:AZC RS01215
gene id: 438753:AZC_RS01215
uniprot id: A8IJ26
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

438753:AZC RS01405
gene id: 438753:AZC_RS01405
uniprot id: A8IJB0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

438753:AZC RS10350
gene id: 438753:AZC_RS10350
uniprot id: A8I396
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.