436717:AOLE RS14250
gene id: 436717:AOLE_RS14250
uniprot id: D8JDS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

436717:AOLE RS06540
gene id: 436717:AOLE_RS06540
uniprot id: D8JGL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS02745
gene id: 436717:AOLE_RS02745
uniprot id: D8JNN4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS02195
gene id: 436717:AOLE_RS02195
uniprot id: D8JN02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

436717:AOLE RS14255
gene id: 436717:AOLE_RS14255
uniprot id: D8JDS5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

436717:AOLE RS02205
gene id: 436717:AOLE_RS02205
uniprot id: D8JN04
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

436717:AOLE RS17670
gene id: 436717:AOLE_RS17670
uniprot id: D8JHL8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

436717:AOLE RS00150
gene id: 436717:AOLE_RS00150
uniprot id: D8JKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

436717:AOLE RS10275
gene id: 436717:AOLE_RS10275
uniprot id: D8JKB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

436717:AOLE RS06745
gene id: 436717:AOLE_RS06745
uniprot id: D8JGQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

436717:AOLE RS02175
gene id: 436717:AOLE_RS02175
uniprot id: D8JMZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

436717:AOLE RS15990
gene id: 436717:AOLE_RS15990
uniprot id: D8JFJ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS16460
gene id: 436717:AOLE_RS16460
uniprot id: D8JG56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

436717:AOLE RS03210
gene id: 436717:AOLE_RS03210
uniprot id: D8JNX7
names: Similarity
messages: Belongs to the YjdM family.

436717:AOLE RS05655
gene id: 436717:AOLE_RS05655
uniprot id: D8JFS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

436717:AOLE RS04590
gene id: 436717:AOLE_RS04590
uniprot id: D8JEE1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS04865
gene id: 436717:AOLE_RS04865
uniprot id: D8JEX9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

436717:AOLE RS14710
gene id: 436717:AOLE_RS14710
uniprot id: D8JE17
names: Similarity
messages: Belongs to the MQO family.

436717:AOLE RS18345
gene id: 436717:AOLE_RS18345
uniprot id: D8JID2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

436717:AOLE RS19125
gene id: 436717:AOLE_RS19125
uniprot id: D8JJ73
names: Similarity
messages: Belongs to the UDPGP type 2 family.

436717:AOLE RS01830
gene id: 436717:AOLE_RS01830
uniprot id: D8JME3
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS15285
gene id: 436717:AOLE_RS15285
uniprot id: D8JER8
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

436717:AOLE RS14700
gene id: 436717:AOLE_RS14700
uniprot id: D8JE15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS02995
gene id: 436717:AOLE_RS02995
uniprot id: D8JNT3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

436717:AOLE RS00470
gene id: 436717:AOLE_RS00470
uniprot id: D8JKV3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

436717:AOLE RS09695
gene id: 436717:AOLE_RS09695
uniprot id: D8JJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

436717:AOLE RS18700
gene id: 436717:AOLE_RS18700
uniprot id: D8JIK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

436717:AOLE RS11900
gene id: 436717:AOLE_RS11900
uniprot id: D8JM05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS17115
gene id: 436717:AOLE_RS17115
uniprot id: D8JGX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

436717:AOLE RS01065
gene id: 436717:AOLE_RS01065
uniprot id: D8JLK7
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS19275
gene id: 436717:AOLE_RS19275
uniprot id: D8JJA4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

436717:AOLE RS16665
gene id: 436717:AOLE_RS16665
uniprot id: D8JG97
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS08595
gene id: 436717:AOLE_RS08595
uniprot id: D8JIX3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS16645
gene id: 436717:AOLE_RS16645
uniprot id: D8JG93
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

436717:AOLE RS08510
gene id: 436717:AOLE_RS08510
uniprot id: D8JIV6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

436717:AOLE RS01020
gene id: 436717:AOLE_RS01020
uniprot id: D8JLJ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS06935
gene id: 436717:AOLE_RS06935
uniprot id: D8JH81
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

436717:AOLE RS17645
gene id: 436717:AOLE_RS17645
uniprot id: D8JHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

436717:AOLE RS01045
gene id: 436717:AOLE_RS01045
uniprot id: D8JLK4
names: Similarity
messages: Belongs to the Gfa family.

436717:AOLE RS06635
gene id: 436717:AOLE_RS06635
uniprot id: D8JGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS04260
gene id: 436717:AOLE_RS04260
uniprot id: D8JE74
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS06175
gene id: 436717:AOLE_RS06175
uniprot id: D8JGE6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

436717:AOLE RS05250
gene id: 436717:AOLE_RS05250
uniprot id: D8JF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

436717:AOLE RS01545
gene id: 436717:AOLE_RS01545
uniprot id: D8JM84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS03460
gene id: 436717:AOLE_RS03460
uniprot id: D8JDD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS16205
gene id: 436717:AOLE_RS16205
uniprot id: D8JG10
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS05160
gene id: 436717:AOLE_RS05160
uniprot id: D8JF39
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

436717:AOLE RS08855
gene id: 436717:AOLE_RS08855
uniprot id: D8JJF7
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS02265
gene id: 436717:AOLE_RS02265
uniprot id: D8JN16
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

436717:AOLE RS01480
gene id: 436717:AOLE_RS01480
uniprot id: D8JM71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

436717:AOLE RS19545
gene id: 436717:AOLE_RS19545
uniprot id: D8JJT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

436717:AOLE RS09270
gene id: 436717:AOLE_RS09270
uniprot id: D8JJP5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

436717:AOLE RS06445
gene id: 436717:AOLE_RS06445
uniprot id: D8JGJ9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

436717:AOLE RS10920
gene id: 436717:AOLE_RS10920
uniprot id: D8JL25
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

436717:AOLE RS18445
gene id: 436717:AOLE_RS18445
uniprot id: D8JIF4
names: Similarity
messages: Belongs to the LOG family.

436717:AOLE RS05925
gene id: 436717:AOLE_RS05925
uniprot id: D8JFX3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS10815
gene id: 436717:AOLE_RS10815
uniprot id: D8JL04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

436717:AOLE RS03290
gene id: 436717:AOLE_RS03290
uniprot id: D8JNZ3
names: Similarity
messages: Belongs to the YkuD family.

436717:AOLE RS04670
gene id: 436717:AOLE_RS04670
uniprot id: D8JEF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

436717:AOLE RS17175
gene id: 436717:AOLE_RS17175
uniprot id: D8JGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

436717:AOLE RS00490
gene id: 436717:AOLE_RS00490
uniprot id: D8JKV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS15380
gene id: 436717:AOLE_RS15380
uniprot id: D8JET7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS04645
gene id: 436717:AOLE_RS04645
uniprot id: D8JEF2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

436717:AOLE RS18175
gene id: 436717:AOLE_RS18175
uniprot id: D8JI99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

436717:AOLE RS13290
gene id: 436717:AOLE_RS13290
uniprot id: D8JNJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

436717:AOLE RS06360
gene id: 436717:AOLE_RS06360
uniprot id: D8JGI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

436717:AOLE RS19205
gene id: 436717:AOLE_RS19205
uniprot id: D8JJ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS14545
gene id: 436717:AOLE_RS14545
uniprot id: D8JDY4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

436717:AOLE RS06665
gene id: 436717:AOLE_RS06665
uniprot id: D8JGP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

436717:AOLE RS04455
gene id: 436717:AOLE_RS04455
uniprot id: D8JEB3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

436717:AOLE RS04560
gene id: 436717:AOLE_RS04560
uniprot id: D8JED5
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

436717:AOLE RS04395
gene id: 436717:AOLE_RS04395
uniprot id: D8JEA1
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS00460
gene id: 436717:AOLE_RS00460
uniprot id: D8JKV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

436717:AOLE RS11570
gene id: 436717:AOLE_RS11570
uniprot id: D8JLT8
names: Similarity
messages: Belongs to the fabD family.

436717:AOLE RS16595
gene id: 436717:AOLE_RS16595
uniprot id: D8JG83
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

436717:AOLE RS15690
gene id: 436717:AOLE_RS15690
uniprot id: D8JFD1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

436717:AOLE RS08500
gene id: 436717:AOLE_RS08500
uniprot id: D8JIV4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

436717:AOLE RS07365
gene id: 436717:AOLE_RS07365
uniprot id: D8JHH0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

436717:AOLE RS00340
gene id: 436717:AOLE_RS00340
uniprot id: D8JKS6
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

436717:AOLE RS03115
gene id: 436717:AOLE_RS03115
uniprot id: D8JNV7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS07095
gene id: 436717:AOLE_RS07095
uniprot id: D8JHB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

436717:AOLE RS13800
gene id: 436717:AOLE_RS13800
uniprot id: D8JP73
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

436717:AOLE RS14140
gene id: 436717:AOLE_RS14140
uniprot id: D8JDQ0
names: Similarity
messages: Belongs to the peptidase M24B family.

436717:AOLE RS12090
gene id: 436717:AOLE_RS12090
uniprot id: D8JM42
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

436717:AOLE RS11875
gene id: 436717:AOLE_RS11875
uniprot id: D8JM00
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS03650
gene id: 436717:AOLE_RS03650
uniprot id: D8JDG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

436717:AOLE RS15540
gene id: 436717:AOLE_RS15540
uniprot id: D8JFA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

436717:AOLE RS19535
gene id: 436717:AOLE_RS19535
uniprot id: D8JJT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

436717:AOLE RS09215
gene id: 436717:AOLE_RS09215
uniprot id: D8JJN4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

436717:AOLE RS16800
gene id: 436717:AOLE_RS16800
uniprot id: D8JGC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

436717:AOLE RS16310
gene id: 436717:AOLE_RS16310
uniprot id: D8JG31
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

436717:AOLE RS17050
gene id: 436717:AOLE_RS17050
uniprot id: D8JGW0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

436717:AOLE RS10765
gene id: 436717:AOLE_RS10765
uniprot id: D8JKL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

436717:AOLE RS07285
gene id: 436717:AOLE_RS07285
uniprot id: D8JHF4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

436717:AOLE RS04605
gene id: 436717:AOLE_RS04605
uniprot id: D8JEE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS05695
gene id: 436717:AOLE_RS05695
uniprot id: D8JFS8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

436717:AOLE RS11090
gene id: 436717:AOLE_RS11090
uniprot id: D8JL59
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS03680
gene id: 436717:AOLE_RS03680
uniprot id: D8JDH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

436717:AOLE RS16565
gene id: 436717:AOLE_RS16565
uniprot id: D8JG77
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

436717:AOLE RS18395
gene id: 436717:AOLE_RS18395
uniprot id: D8JIE4
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

436717:AOLE RS13705
gene id: 436717:AOLE_RS13705
uniprot id: D8JP54
names: Similarity
messages: Belongs to the sulfatase family.

436717:AOLE RS01240
gene id: 436717:AOLE_RS01240
uniprot id: D8JLP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

436717:AOLE RS15905
gene id: 436717:AOLE_RS15905
uniprot id: D8JFH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

436717:AOLE RS14500
gene id: 436717:AOLE_RS14500
uniprot id: D8JDX5
names: Similarity
messages: Belongs to the aldose epimerase family.

436717:AOLE RS15765
gene id: 436717:AOLE_RS15765
uniprot id: D8JFE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS08220
gene id: 436717:AOLE_RS08220
uniprot id: D8JIP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

436717:AOLE RS06785
gene id: 436717:AOLE_RS06785
uniprot id: D8JH51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

436717:AOLE RS08140
gene id: 436717:AOLE_RS08140
uniprot id: D8JIN2
names: Similarity
messages: Belongs to the peptidase S8 family.

436717:AOLE RS07430
gene id: 436717:AOLE_RS07430
uniprot id: D8JHI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

436717:AOLE RS07825
gene id: 436717:AOLE_RS07825
uniprot id: D8JI39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS00430
gene id: 436717:AOLE_RS00430
uniprot id: D8JKU5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS03700
gene id: 436717:AOLE_RS03700
uniprot id: D8JDH7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS16230
gene id: 436717:AOLE_RS16230
uniprot id: D8JG15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

436717:AOLE RS04940
gene id: 436717:AOLE_RS04940
uniprot id: D8JEZ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

436717:AOLE RS04515
gene id: 436717:AOLE_RS04515
uniprot id: D8JEC5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

436717:AOLE RS09235
gene id: 436717:AOLE_RS09235
uniprot id: D8JJN8
names: Similarity
messages: Belongs to the IlvD/Edd family.

436717:AOLE RS09765
gene id: 436717:AOLE_RS09765
uniprot id: D8JK08
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS17105
gene id: 436717:AOLE_RS17105
uniprot id: D8JGX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

436717:AOLE RS10705
gene id: 436717:AOLE_RS10705
uniprot id: D8JKK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

436717:AOLE RS18910
gene id: 436717:AOLE_RS18910
uniprot id: D8JJ28
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

436717:AOLE RS10465
gene id: 436717:AOLE_RS10465
uniprot id: D8JKF3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS06735
gene id: 436717:AOLE_RS06735
uniprot id: D8JGQ7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

436717:AOLE RS12105
gene id: 436717:AOLE_RS12105
uniprot id: D8JM45
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS00800
gene id: 436717:AOLE_RS00800
uniprot id: D8JLF5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

436717:AOLE RS11445
gene id: 436717:AOLE_RS11445
uniprot id: D8JLC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS03835
gene id: 436717:AOLE_RS03835
uniprot id: D8JDK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

436717:AOLE RS14550
gene id: 436717:AOLE_RS14550
uniprot id: D8JDY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS08525
gene id: 436717:AOLE_RS08525
uniprot id: D8JIV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

436717:AOLE RS05135
gene id: 436717:AOLE_RS05135
uniprot id: D8JF34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

436717:AOLE RS06135
gene id: 436717:AOLE_RS06135
uniprot id: D8JGD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS17585
gene id: 436717:AOLE_RS17585
uniprot id: D8JHK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS10730
gene id: 436717:AOLE_RS10730
uniprot id: D8JKK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS16505
gene id: 436717:AOLE_RS16505
uniprot id: D8JG65
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

436717:AOLE RS01280
gene id: 436717:AOLE_RS01280
uniprot id: D8JLQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

436717:AOLE RS14525
gene id: 436717:AOLE_RS14525
uniprot id: D8JDY0
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS01580
gene id: 436717:AOLE_RS01580
uniprot id: D8JM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

436717:AOLE RS17305
gene id: 436717:AOLE_RS17305
uniprot id: D8JH11
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS05750
gene id: 436717:AOLE_RS05750
uniprot id: D8JFT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS19865
gene id: 436717:AOLE_RS19865
uniprot id: D8JK41
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

436717:AOLE RS13555
gene id: 436717:AOLE_RS13555
uniprot id: D8JP22
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

436717:AOLE RS17395
gene id: 436717:AOLE_RS17395
uniprot id: D8JH29
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

436717:AOLE RS02860
gene id: 436717:AOLE_RS02860
uniprot id: D8JNQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS19215
gene id: 436717:AOLE_RS19215
uniprot id: D8JJ91
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

436717:AOLE RS18110
gene id: 436717:AOLE_RS18110
uniprot id: D8JHU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS12970
gene id: 436717:AOLE_RS12970
uniprot id: D8JNC7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

436717:AOLE RS05495
gene id: 436717:AOLE_RS05495
uniprot id: D8JFP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

436717:AOLE RS13440
gene id: 436717:AOLE_RS13440
uniprot id: D8JNM0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS04475
gene id: 436717:AOLE_RS04475
uniprot id: D8JEB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

436717:AOLE RS18045
gene id: 436717:AOLE_RS18045
uniprot id: D8JHU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

436717:AOLE RS15460
gene id: 436717:AOLE_RS15460
uniprot id: D8JF87
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

436717:AOLE RS15840
gene id: 436717:AOLE_RS15840
uniprot id: D8JFG3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

436717:AOLE RS02660
gene id: 436717:AOLE_RS02660
uniprot id: D8JN82
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

436717:AOLE RS18960
gene id: 436717:AOLE_RS18960
uniprot id: D8JJ38
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS16635
gene id: 436717:AOLE_RS16635
uniprot id: D8JG91
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS11190
gene id: 436717:AOLE_RS11190
uniprot id: D8JL78
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS16370
gene id: 436717:AOLE_RS16370
uniprot id: D8JG38
names: Similarity
messages: Belongs to the MlaA family.

436717:AOLE RS13360
gene id: 436717:AOLE_RS13360
uniprot id: D8JNK4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS07485
gene id: 436717:AOLE_RS07485
uniprot id: D8JHX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

436717:AOLE RS12665
gene id: 436717:AOLE_RS12665
uniprot id: D8JMU3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

436717:AOLE RS06430
gene id: 436717:AOLE_RS06430
uniprot id: D8JGJ6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

436717:AOLE RS02285
gene id: 436717:AOLE_RS02285
uniprot id: D8JN21
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

436717:AOLE RS14520
gene id: 436717:AOLE_RS14520
uniprot id: D8JDX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

436717:AOLE RS00520
gene id: 436717:AOLE_RS00520
uniprot id: D8JKW3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

436717:AOLE RS03920
gene id: 436717:AOLE_RS03920
uniprot id: D8JDM0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

436717:AOLE RS10215
gene id: 436717:AOLE_RS10215
uniprot id: D8JKA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS10660
gene id: 436717:AOLE_RS10660
uniprot id: D8JKJ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS10635
gene id: 436717:AOLE_RS10635
uniprot id: D8JKI7
names: Similarity
messages: Belongs to the HesB/IscA family.

436717:AOLE RS13510
gene id: 436717:AOLE_RS13510
uniprot id: D8JP13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

436717:AOLE RS11385
gene id: 436717:AOLE_RS11385
uniprot id: D8JLB7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

436717:AOLE RS06185
gene id: 436717:AOLE_RS06185
uniprot id: D8JGE8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS09115
gene id: 436717:AOLE_RS09115
uniprot id: D8JJL4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS08560
gene id: 436717:AOLE_RS08560
uniprot id: D8JIW6
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

436717:AOLE RS04480
gene id: 436717:AOLE_RS04480
uniprot id: D8JEB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

436717:AOLE RS20580
gene id: 436717:AOLE_RS20580
uniprot id: D8JIK8
names: Cofactor
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

436717:AOLE RS06005
gene id: 436717:AOLE_RS06005
uniprot id: D8JFY5
names: Subcellular Location Annotation
messages: Cytoplasm

436717:AOLE RS13495
gene id: 436717:AOLE_RS13495
uniprot id: D8JP10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

436717:AOLE RS13550
gene id: 436717:AOLE_RS13550
uniprot id: D8JP21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

436717:AOLE RS15855
gene id: 436717:AOLE_RS15855
uniprot id: D8JFG6
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS17830
gene id: 436717:AOLE_RS17830
uniprot id: D8JHP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

436717:AOLE RS14515
gene id: 436717:AOLE_RS14515
uniprot id: D8JDX8
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

436717:AOLE RS10750
gene id: 436717:AOLE_RS10750
uniprot id: D8JKL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS07470
gene id: 436717:AOLE_RS07470
uniprot id: D8JHW8
names: Similarity
messages: Belongs to the Skp family.

436717:AOLE RS09790
gene id: 436717:AOLE_RS09790
uniprot id: D8JK13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS10515
gene id: 436717:AOLE_RS10515
uniprot id: D8JKG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS02955
gene id: 436717:AOLE_RS02955
uniprot id: D8JNS5
names: Similarity
messages: Belongs to the TrpF family.

436717:AOLE RS18050
gene id: 436717:AOLE_RS18050
uniprot id: D8JHU2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

436717:AOLE RS12010
gene id: 436717:AOLE_RS12010
uniprot id: D8JM27
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS14725
gene id: 436717:AOLE_RS14725
uniprot id: D8JE20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

436717:AOLE RS18070
gene id: 436717:AOLE_RS18070
uniprot id: D8JES9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

436717:AOLE RS01665
gene id: 436717:AOLE_RS01665
uniprot id: D8JMA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

436717:AOLE RS17155
gene id: 436717:AOLE_RS17155
uniprot id: D8JGY1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

436717:AOLE RS09530
gene id: 436717:AOLE_RS09530
uniprot id: D8JJW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

436717:AOLE RS15470
gene id: 436717:AOLE_RS15470
uniprot id: D8JF89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

436717:AOLE RS17360
gene id: 436717:AOLE_RS17360
uniprot id: D8JH22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

436717:AOLE RS16955
gene id: 436717:AOLE_RS16955
uniprot id: D8JGU1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

436717:AOLE RS00860
gene id: 436717:AOLE_RS00860
uniprot id: D8JLG7
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS00395
gene id: 436717:AOLE_RS00395
uniprot id: D8JKT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

436717:AOLE RS07100
gene id: 436717:AOLE_RS07100
uniprot id: D8JHB5
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

436717:AOLE RS18265
gene id: 436717:AOLE_RS18265
uniprot id: D8JIB6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

436717:AOLE RS02230
gene id: 436717:AOLE_RS02230
uniprot id: D8JN09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

436717:AOLE RS14345
gene id: 436717:AOLE_RS14345
uniprot id: D8JDU4
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

436717:AOLE RS01975
gene id: 436717:AOLE_RS01975
uniprot id: D8JMH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

436717:AOLE RS06045
gene id: 436717:AOLE_RS06045
uniprot id: D8JFZ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

436717:AOLE RS15135
gene id: 436717:AOLE_RS15135
uniprot id: D8JEN7
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS04465
gene id: 436717:AOLE_RS04465
uniprot id: D8JEB5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS16755
gene id: 436717:AOLE_RS16755
uniprot id: D8JGB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

436717:AOLE RS00630
gene id: 436717:AOLE_RS00630
uniprot id: D8JKY5
names: Similarity
messages: Belongs to the FAD-dependent urate hydroxylase family.

436717:AOLE RS06205
gene id: 436717:AOLE_RS06205
uniprot id: D8JGF2
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS11895
gene id: 436717:AOLE_RS11895
uniprot id: D8JM04
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

436717:AOLE RS04965
gene id: 436717:AOLE_RS04965
uniprot id: D8JF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

436717:AOLE RS00440
gene id: 436717:AOLE_RS00440
uniprot id: D8JKU7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

436717:AOLE RS09135
gene id: 436717:AOLE_RS09135
uniprot id: D8JJL8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

436717:AOLE RS02000
gene id: 436717:AOLE_RS02000
uniprot id: D8JMH8
names: Similarity
messages: Belongs to the DEAD box helicase family.

436717:AOLE RS11935
gene id: 436717:AOLE_RS11935
uniprot id: D8JM12
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

436717:AOLE RS03215
gene id: 436717:AOLE_RS03215
uniprot id: D8JNX8
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

436717:AOLE RS16150
gene id: 436717:AOLE_RS16150
uniprot id: D8JG03
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS08740
gene id: 436717:AOLE_RS08740
uniprot id: D8JJ02
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS02770
gene id: 436717:AOLE_RS02770
uniprot id: D8JNN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

436717:AOLE RS04900
gene id: 436717:AOLE_RS04900
uniprot id: D8JEY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS10665
gene id: 436717:AOLE_RS10665
uniprot id: D8JKJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

436717:AOLE RS05445
gene id: 436717:AOLE_RS05445
uniprot id: D8JFN0
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

436717:AOLE RS19435
gene id: 436717:AOLE_RS19435
uniprot id: D8JJD1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

436717:AOLE RS12080
gene id: 436717:AOLE_RS12080
uniprot id: D8JM40
names: Similarity
messages: Belongs to the gamma-class carbonic anhydrase family.

436717:AOLE RS07080
gene id: 436717:AOLE_RS07080
uniprot id: D8JHB1
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS10400
gene id: 436717:AOLE_RS10400
uniprot id: D8JKE0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

436717:AOLE RS15260
gene id: 436717:AOLE_RS15260
uniprot id: D8JER2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

436717:AOLE RS04890
gene id: 436717:AOLE_RS04890
uniprot id: D8JEY4
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

436717:AOLE RS02190
gene id: 436717:AOLE_RS02190
uniprot id: D8JN01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

436717:AOLE RS09325
gene id: 436717:AOLE_RS09325
uniprot id: D8JJQ6
names: Similarity
messages: Belongs to the NAPRTase family.

436717:AOLE RS12755
gene id: 436717:AOLE_RS12755
uniprot id: D8JMW1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS07210
gene id: 436717:AOLE_RS07210
uniprot id: D8JHD8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

436717:AOLE RS16930
gene id: 436717:AOLE_RS16930
uniprot id: D8JGT6
names: Similarity
messages: Belongs to the YfgM family.

436717:AOLE RS06740
gene id: 436717:AOLE_RS06740
uniprot id: D8JGQ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

436717:AOLE RS18600
gene id: 436717:AOLE_RS18600
uniprot id: D8JII1
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS01710
gene id: 436717:AOLE_RS01710
uniprot id: D8JMB8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

436717:AOLE RS08285
gene id: 436717:AOLE_RS08285
uniprot id: D8JIR1
names: Similarity
messages: Belongs to the UPF0319 family.

436717:AOLE RS03410
gene id: 436717:AOLE_RS03410
uniprot id: D8JDC1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

436717:AOLE RS04945
gene id: 436717:AOLE_RS04945
uniprot id: D8JEZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS04685
gene id: 436717:AOLE_RS04685
uniprot id: D8JEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

436717:AOLE RS19050
gene id: 436717:AOLE_RS19050
uniprot id: D8JJ58
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

436717:AOLE RS00130
gene id: 436717:AOLE_RS00130
uniprot id: D8JKN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS08190
gene id: 436717:AOLE_RS08190
uniprot id: D8JIP2
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

436717:AOLE RS17755
gene id: 436717:AOLE_RS17755
uniprot id: D8JHN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS10650
gene id: 436717:AOLE_RS10650
uniprot id: D8JKJ0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

436717:AOLE RS04495
gene id: 436717:AOLE_RS04495
uniprot id: D8JEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

436717:AOLE RS09175
gene id: 436717:AOLE_RS09175
uniprot id: D8JJM6
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS07235
gene id: 436717:AOLE_RS07235
uniprot id: D8JHE3
names: Similarity
messages: Belongs to the IucA/IucC family.

436717:AOLE RS15490
gene id: 436717:AOLE_RS15490
uniprot id: D8JF93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

436717:AOLE RS00390
gene id: 436717:AOLE_RS00390
uniprot id: D8JKT6
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS11380
gene id: 436717:AOLE_RS11380
uniprot id: D8JLB6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

436717:AOLE RS03085
gene id: 436717:AOLE_RS03085
uniprot id: D8JNV1
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

436717:AOLE RS19075
gene id: 436717:AOLE_RS19075
uniprot id: D8JJ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

436717:AOLE RS05910
gene id: 436717:AOLE_RS05910
uniprot id: D8JFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS12915
gene id: 436717:AOLE_RS12915
uniprot id: D8JNB6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

436717:AOLE RS13795
gene id: 436717:AOLE_RS13795
uniprot id: D8JP72
names: Similarity
messages: Belongs to the DapA family.

436717:AOLE RS05165
gene id: 436717:AOLE_RS05165
uniprot id: D8JF40
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

436717:AOLE RS06105
gene id: 436717:AOLE_RS06105
uniprot id: D8JGD2
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

436717:AOLE RS02590
gene id: 436717:AOLE_RS02590
uniprot id: D8JN73
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS16385
gene id: 436717:AOLE_RS16385
uniprot id: D8JG41
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

436717:AOLE RS04200
gene id: 436717:AOLE_RS04200
uniprot id: D8JE61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS04855
gene id: 436717:AOLE_RS04855
uniprot id: D8JEX7
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

436717:AOLE RS13630
gene id: 436717:AOLE_RS13630
uniprot id: D8JP39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS10625
gene id: 436717:AOLE_RS10625
uniprot id: D8JKI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

436717:AOLE RS00750
gene id: 436717:AOLE_RS00750
uniprot id: D8JLE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

436717:AOLE RS08790
gene id: 436717:AOLE_RS08790
uniprot id: D8JJ12
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS13010
gene id: 436717:AOLE_RS13010
uniprot id: D8JND5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

436717:AOLE RS03525
gene id: 436717:AOLE_RS03525
uniprot id: D8JDE3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

436717:AOLE RS04705
gene id: 436717:AOLE_RS04705
uniprot id: D8JEG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

436717:AOLE RS15395
gene id: 436717:AOLE_RS15395
uniprot id: D8JET9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PDR/VanB family. CntB subfamily.
messages: Binds 1 2Fe-2S cluster.
messages: Composed of an oxygenase subunit and a reductase subunit.
messages: Converts carnitine to trimethylamine and malic semialdehyde.

436717:AOLE RS03770
gene id: 436717:AOLE_RS03770
uniprot id: D8JDJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

436717:AOLE RS02355
gene id: 436717:AOLE_RS02355
uniprot id: D8JN31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS06440
gene id: 436717:AOLE_RS06440
uniprot id: D8JGJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

436717:AOLE RS01370
gene id: 436717:AOLE_RS01370
uniprot id: D8JM53
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

436717:AOLE RS05705
gene id: 436717:AOLE_RS05705
uniprot id: D8JFT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

436717:AOLE RS02925
gene id: 436717:AOLE_RS02925
uniprot id: D8JNR9
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

436717:AOLE RS03035
gene id: 436717:AOLE_RS03035
uniprot id: D8JNU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

436717:AOLE RS06555
gene id: 436717:AOLE_RS06555
uniprot id: D8JGM1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS01840
gene id: 436717:AOLE_RS01840
uniprot id: D8JME5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

436717:AOLE RS08435
gene id: 436717:AOLE_RS08435
uniprot id: D8JIU0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

436717:AOLE RS04080
gene id: 436717:AOLE_RS04080
uniprot id: D8JE36
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS15355
gene id: 436717:AOLE_RS15355
uniprot id: D8JET2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

436717:AOLE RS19490
gene id: 436717:AOLE_RS19490
uniprot id: D8JJE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

436717:AOLE RS05825
gene id: 436717:AOLE_RS05825
uniprot id: D8JFV3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

436717:AOLE RS06460
gene id: 436717:AOLE_RS06460
uniprot id: D8JGK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

436717:AOLE RS08785
gene id: 436717:AOLE_RS08785
uniprot id: D8JJ11
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS12720
gene id: 436717:AOLE_RS12720
uniprot id: D8JMV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS09930
gene id: 436717:AOLE_RS09930
uniprot id: D8JK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS00930
gene id: 436717:AOLE_RS00930
uniprot id: D8JLI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

436717:AOLE RS06600
gene id: 436717:AOLE_RS06600
uniprot id: D8JGN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

436717:AOLE RS13805
gene id: 436717:AOLE_RS13805
uniprot id: D8JP74
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS10585
gene id: 436717:AOLE_RS10585
uniprot id: D8JKH7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS15310
gene id: 436717:AOLE_RS15310
uniprot id: D8JES3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

436717:AOLE RS04320
gene id: 436717:AOLE_RS04320
uniprot id: D8JE86
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

436717:AOLE RS04905
gene id: 436717:AOLE_RS04905
uniprot id: D8JEY8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS14295
gene id: 436717:AOLE_RS14295
uniprot id: D8JDT3
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS18125
gene id: 436717:AOLE_RS18125
uniprot id: D8JHV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

436717:AOLE RS00350
gene id: 436717:AOLE_RS00350
uniprot id: D8JKS8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS14090
gene id: 436717:AOLE_RS14090
uniprot id: D8JPD2
names: Similarity
messages: Belongs to the UPF0102 family.

436717:AOLE RS07730
gene id: 436717:AOLE_RS07730
uniprot id: D8JI20
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

436717:AOLE RS12370
gene id: 436717:AOLE_RS12370
uniprot id: D8JMN2
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS11415
gene id: 436717:AOLE_RS11415
uniprot id: D8JLC3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

436717:AOLE RS00695
gene id: 436717:AOLE_RS00695
uniprot id: D8JLD4
names: Similarity
messages: Belongs to the ArsC family.

436717:AOLE RS14180
gene id: 436717:AOLE_RS14180
uniprot id: D8JDQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

436717:AOLE RS03260
gene id: 436717:AOLE_RS03260
uniprot id: D8JNY7
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

436717:AOLE RS12895
gene id: 436717:AOLE_RS12895
uniprot id: D8JNB2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

436717:AOLE RS11840
gene id: 436717:AOLE_RS11840
uniprot id: D8JLZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS04870
gene id: 436717:AOLE_RS04870
uniprot id: D8JEY0
names: Similarity
messages: Belongs to the peptidase S11 family.

436717:AOLE RS05635
gene id: 436717:AOLE_RS05635
uniprot id: D8JFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS01345
gene id: 436717:AOLE_RS01345
uniprot id: D8JLR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Membrane

436717:AOLE RS19500
gene id: 436717:AOLE_RS19500
uniprot id: D8JJE4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

436717:AOLE RS14230
gene id: 436717:AOLE_RS14230
uniprot id: D8JDS0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

436717:AOLE RS15980
gene id: 436717:AOLE_RS15980
uniprot id: D8JFJ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS18310
gene id: 436717:AOLE_RS18310
uniprot id: D8JIC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

436717:AOLE RS01000
gene id: 436717:AOLE_RS01000
uniprot id: D8JLJ5
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS14850
gene id: 436717:AOLE_RS14850
uniprot id: D8JEH9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

436717:AOLE RS09510
gene id: 436717:AOLE_RS09510
uniprot id: D8JJV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS02170
gene id: 436717:AOLE_RS02170
uniprot id: D8JMZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

436717:AOLE RS06770
gene id: 436717:AOLE_RS06770
uniprot id: D8JH48
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

436717:AOLE RS09690
gene id: 436717:AOLE_RS09690
uniprot id: D8JJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

436717:AOLE RS17065
gene id: 436717:AOLE_RS17065
uniprot id: D8JGW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS01920
gene id: 436717:AOLE_RS01920
uniprot id: D8JMG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

436717:AOLE RS01395
gene id: 436717:AOLE_RS01395
uniprot id: D8JM58
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

436717:AOLE RS01005
gene id: 436717:AOLE_RS01005
uniprot id: D8JLJ6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS13030
gene id: 436717:AOLE_RS13030
uniprot id: D8JND9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

436717:AOLE RS18030
gene id: 436717:AOLE_RS18030
uniprot id: D3JTG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

436717:AOLE RS17565
gene id: 436717:AOLE_RS17565
uniprot id: D8JHJ7
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

436717:AOLE RS03345
gene id: 436717:AOLE_RS03345
uniprot id: D8JNZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS19355
gene id: 436717:AOLE_RS19355
uniprot id: D8JJC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

436717:AOLE RS14060
gene id: 436717:AOLE_RS14060
uniprot id: D8JPC6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

436717:AOLE RS11885
gene id: 436717:AOLE_RS11885
uniprot id: D8JM02
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

436717:AOLE RS12525
gene id: 436717:AOLE_RS12525
uniprot id: D8JMR4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS17855
gene id: 436717:AOLE_RS17855
uniprot id: D8JHQ3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

436717:AOLE RS15580
gene id: 436717:AOLE_RS15580
uniprot id: D8JFA9
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

436717:AOLE RS03430
gene id: 436717:AOLE_RS03430
uniprot id: D8JDC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

436717:AOLE RS14105
gene id: 436717:AOLE_RS14105
uniprot id: D8JPD5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS13005
gene id: 436717:AOLE_RS13005
uniprot id: D8JND4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS00640
gene id: 436717:AOLE_RS00640
uniprot id: D8JKY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

436717:AOLE RS02225
gene id: 436717:AOLE_RS02225
uniprot id: D8JN08
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

436717:AOLE RS06590
gene id: 436717:AOLE_RS06590
uniprot id: D8JGM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

436717:AOLE RS06395
gene id: 436717:AOLE_RS06395
uniprot id: D8JGJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

436717:AOLE RS11700
gene id: 436717:AOLE_RS11700
uniprot id: D8JLW4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS16650
gene id: 436717:AOLE_RS16650
uniprot id: D8JG94
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

436717:AOLE RS16430
gene id: 436717:AOLE_RS16430
uniprot id: D8JG50
names: Similarity
messages: Belongs to the YggT family.

436717:AOLE RS08145
gene id: 436717:AOLE_RS08145
uniprot id: D8JIN3
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS06800
gene id: 436717:AOLE_RS06800
uniprot id: D8JH54
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

436717:AOLE RS07410
gene id: 436717:AOLE_RS07410
uniprot id: D8JHH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

436717:AOLE RS00385
gene id: 436717:AOLE_RS00385
uniprot id: D8JKT5
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

436717:AOLE RS14690
gene id: 436717:AOLE_RS14690
uniprot id: D8JE13
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS03285
gene id: 436717:AOLE_RS03285
uniprot id: D8JNZ2
names: Subcellular Location Annotation
messages: Cell inner membrane

436717:AOLE RS00700
gene id: 436717:AOLE_RS00700
uniprot id: D8JLD5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

436717:AOLE RS16570
gene id: 436717:AOLE_RS16570
uniprot id: D8JG78
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

436717:AOLE RS12535
gene id: 436717:AOLE_RS12535
uniprot id: D8JMR6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

436717:AOLE RS15130
gene id: 436717:AOLE_RS15130
uniprot id: D8JEN6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

436717:AOLE RS07160
gene id: 436717:AOLE_RS07160
uniprot id: D8JHC8
names: Similarity
messages: Belongs to the peptidase C59 family.

436717:AOLE RS01225
gene id: 436717:AOLE_RS01225
uniprot id: D8JLN9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

436717:AOLE RS02985
gene id: 436717:AOLE_RS02985
uniprot id: D8JNT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

436717:AOLE RS18660
gene id: 436717:AOLE_RS18660
uniprot id: D8JIJ4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS13695
gene id: 436717:AOLE_RS13695
uniprot id: D8JP52
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

436717:AOLE RS19120
gene id: 436717:AOLE_RS19120
uniprot id: D8JJ72
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

436717:AOLE RS00580
gene id: 436717:AOLE_RS00580
uniprot id: D8JKX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

436717:AOLE RS15465
gene id: 436717:AOLE_RS15465
uniprot id: D8JF88
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

436717:AOLE RS05920
gene id: 436717:AOLE_RS05920
uniprot id: D8JFX2
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS10545
gene id: 436717:AOLE_RS10545
uniprot id: D8JKG9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

436717:AOLE RS10900
gene id: 436717:AOLE_RS10900
uniprot id: D8JL21
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

436717:AOLE RS00735
gene id: 436717:AOLE_RS00735
uniprot id: D8JLE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

436717:AOLE RS05660
gene id: 436717:AOLE_RS05660
uniprot id: D8JFS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

436717:AOLE RS01500
gene id: 436717:AOLE_RS01500
uniprot id: D8JM75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

436717:AOLE RS18055
gene id: 436717:AOLE_RS18055
uniprot id: D8JHU3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

436717:AOLE RS18890
gene id: 436717:AOLE_RS18890
uniprot id: D8JJ24
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS02050
gene id: 436717:AOLE_RS02050
uniprot id: D8JMX4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

436717:AOLE RS19460
gene id: 436717:AOLE_RS19460
uniprot id: D8JJD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

436717:AOLE RS18455
gene id: 436717:AOLE_RS18455
uniprot id: D8JIF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

436717:AOLE RS01735
gene id: 436717:AOLE_RS01735
uniprot id: D8JMC4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

436717:AOLE RS02385
gene id: 436717:AOLE_RS02385
uniprot id: D8JN37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

436717:AOLE RS04090
gene id: 436717:AOLE_RS04090
uniprot id: D8JE38
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

436717:AOLE RS00120
gene id: 436717:AOLE_RS00120
uniprot id: D8JKN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

436717:AOLE RS12995
gene id: 436717:AOLE_RS12995
uniprot id: D8JND2
names: Similarity
messages: Belongs to the IMPACT family.

436717:AOLE RS11970
gene id: 436717:AOLE_RS11970
uniprot id: D8JM19
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

436717:AOLE RS18425
gene id: 436717:AOLE_RS18425
uniprot id: D8JIF0
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS14800
gene id: 436717:AOLE_RS14800
uniprot id: D8JEG9
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

436717:AOLE RS06500
gene id: 436717:AOLE_RS06500
uniprot id: D8JGL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS18365
gene id: 436717:AOLE_RS18365
uniprot id: D8JID7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

436717:AOLE RS07505
gene id: 436717:AOLE_RS07505
uniprot id: D8JHX5
names: Similarity
messages: Belongs to the HSP15 family.

436717:AOLE RS05070
gene id: 436717:AOLE_RS05070
uniprot id: D8JF21
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

436717:AOLE RS17375
gene id: 436717:AOLE_RS17375
uniprot id: D8JH25
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS00615
gene id: 436717:AOLE_RS00615
uniprot id: D8JKY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

436717:AOLE RS02085
gene id: 436717:AOLE_RS02085
uniprot id: D8JMY0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

436717:AOLE RS03190
gene id: 436717:AOLE_RS03190
uniprot id: D8JNX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

436717:AOLE RS18610
gene id: 436717:AOLE_RS18610
uniprot id: D8JII3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

436717:AOLE RS17845
gene id: 436717:AOLE_RS17845
uniprot id: D8JHQ1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

436717:AOLE RS00140
gene id: 436717:AOLE_RS00140
uniprot id: D8JKN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS01495
gene id: 436717:AOLE_RS01495
uniprot id: D8JM74
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS05050
gene id: 436717:AOLE_RS05050
uniprot id: D8JF17
names: Similarity
messages: Belongs to the peptidase S49 family.

436717:AOLE RS00380
gene id: 436717:AOLE_RS00380
uniprot id: D8JKT4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS02760
gene id: 436717:AOLE_RS02760
uniprot id: D8JNN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS06850
gene id: 436717:AOLE_RS06850
uniprot id: D8JH64
names: Similarity
messages: Belongs to the peptidase M1 family.

436717:AOLE RS00065
gene id: 436717:AOLE_RS00065
uniprot id: D8JKM6
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

436717:AOLE RS11240
gene id: 436717:AOLE_RS11240
uniprot id: D8JL87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

436717:AOLE RS14155
gene id: 436717:AOLE_RS14155
uniprot id: D8JDQ3
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

436717:AOLE RS12065
gene id: 436717:AOLE_RS12065
uniprot id: D8JM37
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS06375
gene id: 436717:AOLE_RS06375
uniprot id: D8JGI6
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

436717:AOLE RS02070
gene id: 436717:AOLE_RS02070
uniprot id: D8JMX7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

436717:AOLE RS03170
gene id: 436717:AOLE_RS03170
uniprot id: D8JNW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS09935
gene id: 436717:AOLE_RS09935
uniprot id: D8JK45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS02260
gene id: 436717:AOLE_RS02260
uniprot id: D8JN15
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS09680
gene id: 436717:AOLE_RS09680
uniprot id: D8JJZ1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS08395
gene id: 436717:AOLE_RS08395
uniprot id: D8JIT2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

436717:AOLE RS03600
gene id: 436717:AOLE_RS03600
uniprot id: D8JDF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS18100
gene id: 436717:AOLE_RS18100
uniprot id: D8JHU7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.

436717:AOLE RS03895
gene id: 436717:AOLE_RS03895
uniprot id: D8JDL5
names: Similarity
messages: Belongs to the CapA family.

436717:AOLE RS18855
gene id: 436717:AOLE_RS18855
uniprot id: D3JTG4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS09925
gene id: 436717:AOLE_RS09925
uniprot id: D8JK43
names: Cofactor
messages: Binds 1 zinc ion per subunit.

436717:AOLE RS17465
gene id: 436717:AOLE_RS17465
uniprot id: D8JH41
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS00200
gene id: 436717:AOLE_RS00200
uniprot id: D8JKP8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS05040
gene id: 436717:AOLE_RS05040
uniprot id: D8JF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS18815
gene id: 436717:AOLE_RS18815
uniprot id: D8JIM3
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS04535
gene id: 436717:AOLE_RS04535
uniprot id: D8JEC9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

436717:AOLE RS05620
gene id: 436717:AOLE_RS05620
uniprot id: D8JFR3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

436717:AOLE RS00165
gene id: 436717:AOLE_RS00165
uniprot id: D8JKP1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

436717:AOLE RS05010
gene id: 436717:AOLE_RS05010
uniprot id: D8JF09
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

436717:AOLE RS13390
gene id: 436717:AOLE_RS13390
uniprot id: D8JNL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

436717:AOLE RS02165
gene id: 436717:AOLE_RS02165
uniprot id: D8JMZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

436717:AOLE RS18355
gene id: 436717:AOLE_RS18355
uniprot id: D8JID5
names: Similarity
messages: Belongs to the P(II) protein family.

436717:AOLE RS17035
gene id: 436717:AOLE_RS17035
uniprot id: D8JGV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

436717:AOLE RS02250
gene id: 436717:AOLE_RS02250
uniprot id: D8JN13
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

436717:AOLE RS02890
gene id: 436717:AOLE_RS02890
uniprot id: D8JNR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS00895
gene id: 436717:AOLE_RS00895
uniprot id: D8JLH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

436717:AOLE RS08555
gene id: 436717:AOLE_RS08555
uniprot id: D8JIW5
names: Similarity
messages: Belongs to the OprB family.

436717:AOLE RS14245
gene id: 436717:AOLE_RS14245
uniprot id: D8JDS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

436717:AOLE RS00530
gene id: 436717:AOLE_RS00530
uniprot id: D8JKW5
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

436717:AOLE RS07970
gene id: 436717:AOLE_RS07970
uniprot id: D8JI69
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

436717:AOLE RS02305
gene id: 436717:AOLE_RS02305
uniprot id: D8JN25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

436717:AOLE RS14330
gene id: 436717:AOLE_RS14330
uniprot id: D8JDU1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS15525
gene id: 436717:AOLE_RS15525
uniprot id: D8JF98
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

436717:AOLE RS14130
gene id: 436717:AOLE_RS14130
uniprot id: D8JDP8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

436717:AOLE RS05230
gene id: 436717:AOLE_RS05230
uniprot id: D8JF53
names: Subcellular Location Annotation
messages: Cytoplasm

436717:AOLE RS03255
gene id: 436717:AOLE_RS03255
uniprot id: D8JNY6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

436717:AOLE RS10120
gene id: 436717:AOLE_RS10120
uniprot id: D8JK82
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS00015
gene id: 436717:AOLE_RS00015
uniprot id: D8JKL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

436717:AOLE RS16740
gene id: 436717:AOLE_RS16740
uniprot id: D8JGB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

436717:AOLE RS03910
gene id: 436717:AOLE_RS03910
uniprot id: D8JDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

436717:AOLE RS19360
gene id: 436717:AOLE_RS19360
uniprot id: D8JJC1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

436717:AOLE RS10945
gene id: 436717:AOLE_RS10945
uniprot id: D8JL30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

436717:AOLE RS00190
gene id: 436717:AOLE_RS00190
uniprot id: D8JKP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

436717:AOLE RS12075
gene id: 436717:AOLE_RS12075
uniprot id: D8JM39
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

436717:AOLE RS00980
gene id: 436717:AOLE_RS00980
uniprot id: D8JLJ1
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

436717:AOLE RS14430
gene id: 436717:AOLE_RS14430
uniprot id: D8JDW1
names: Similarity
messages: Belongs to the sulfatase family.

436717:AOLE RS11725
gene id: 436717:AOLE_RS11725
uniprot id: D8JLW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

436717:AOLE RS17030
gene id: 436717:AOLE_RS17030
uniprot id: D8JGV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

436717:AOLE RS04765
gene id: 436717:AOLE_RS04765
uniprot id: D8JEV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

436717:AOLE RS05330
gene id: 436717:AOLE_RS05330
uniprot id: D8JF75
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

436717:AOLE RS12695
gene id: 436717:AOLE_RS12695
uniprot id: D8JMU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS05535
gene id: 436717:AOLE_RS05535
uniprot id: D8JFP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

436717:AOLE RS09105
gene id: 436717:AOLE_RS09105
uniprot id: D8JJL2
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

436717:AOLE RS06475
gene id: 436717:AOLE_RS06475
uniprot id: D8JGK5
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS17235
gene id: 436717:AOLE_RS17235
uniprot id: D8JGZ7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

436717:AOLE RS04240
gene id: 436717:AOLE_RS04240
uniprot id: D8JE69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS02780
gene id: 436717:AOLE_RS02780
uniprot id: D8JNP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

436717:AOLE RS14375
gene id: 436717:AOLE_RS14375
uniprot id: D8JDV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

436717:AOLE RS01490
gene id: 436717:AOLE_RS01490
uniprot id: D8JM73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

436717:AOLE RS18630
gene id: 436717:AOLE_RS18630
uniprot id: D8JII7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

436717:AOLE RS00675
gene id: 436717:AOLE_RS00675
uniprot id: D8JKZ4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS03845
gene id: 436717:AOLE_RS03845
uniprot id: D8JDK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

436717:AOLE RS09195
gene id: 436717:AOLE_RS09195
uniprot id: D8JJN0
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

436717:AOLE RS14695
gene id: 436717:AOLE_RS14695
uniprot id: D8JE14
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

436717:AOLE RS16200
gene id: 436717:AOLE_RS16200
uniprot id: D8JG09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS14450
gene id: 436717:AOLE_RS14450
uniprot id: D8JDW5
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

436717:AOLE RS02120
gene id: 436717:AOLE_RS02120
uniprot id: D8JMY7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

436717:AOLE RS15850
gene id: 436717:AOLE_RS15850
uniprot id: D8JFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

436717:AOLE RS13895
gene id: 436717:AOLE_RS13895
uniprot id: D8JP93
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

436717:AOLE RS04225
gene id: 436717:AOLE_RS04225
uniprot id: D8JE66
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

436717:AOLE RS02580
gene id: 436717:AOLE_RS02580
uniprot id: D8JN71
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

436717:AOLE RS15810
gene id: 436717:AOLE_RS15810
uniprot id: D8JFF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

436717:AOLE RS08100
gene id: 436717:AOLE_RS08100
uniprot id: D8JI95
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

436717:AOLE RS07340
gene id: 436717:AOLE_RS07340
uniprot id: D8JHG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

436717:AOLE RS10820
gene id: 436717:AOLE_RS10820
uniprot id: D8JL05
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

436717:AOLE RS11485
gene id: 436717:AOLE_RS11485
uniprot id: D8JLS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

436717:AOLE RS17025
gene id: 436717:AOLE_RS17025
uniprot id: D8JGV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

436717:AOLE RS11085
gene id: 436717:AOLE_RS11085
uniprot id: D8JL58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

436717:AOLE RS15215
gene id: 436717:AOLE_RS15215
uniprot id: D8JEQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

436717:AOLE RS01890
gene id: 436717:AOLE_RS01890
uniprot id: D8JMF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS12985
gene id: 436717:AOLE_RS12985
uniprot id: D8JND0
names: Similarity
messages: Belongs to the universal stress protein A family.

436717:AOLE RS01625
gene id: 436717:AOLE_RS01625
uniprot id: D8JMA0
names: Similarity
messages: Belongs to the RelA/SpoT family.

436717:AOLE RS10930
gene id: 436717:AOLE_RS10930
uniprot id: D8JL27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

436717:AOLE RS12380
gene id: 436717:AOLE_RS12380
uniprot id: D8JMN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS09915
gene id: 436717:AOLE_RS09915
uniprot id: D8JK40
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

436717:AOLE RS09905
gene id: 436717:AOLE_RS09905
uniprot id: D8JK38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

436717:AOLE RS06325
gene id: 436717:AOLE_RS06325
uniprot id: D8JGH6
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS02380
gene id: 436717:AOLE_RS02380
uniprot id: D8JN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

436717:AOLE RS17780
gene id: 436717:AOLE_RS17780
uniprot id: D8JHP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

436717:AOLE RS01795
gene id: 436717:AOLE_RS01795
uniprot id: D8JMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

436717:AOLE RS16455
gene id: 436717:AOLE_RS16455
uniprot id: D8JG55
names: Similarity
messages: Belongs to the thioredoxin family.

436717:AOLE RS15790
gene id: 436717:AOLE_RS15790
uniprot id: D8JFF2
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS01915
gene id: 436717:AOLE_RS01915
uniprot id: D8JMG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

436717:AOLE RS19350
gene id: 436717:AOLE_RS19350
uniprot id: D8JJB9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

436717:AOLE RS19210
gene id: 436717:AOLE_RS19210
uniprot id: D8JJ90
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

436717:AOLE RS17995
gene id: 436717:AOLE_RS17995
uniprot id: D8JHT1
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS17860
gene id: 436717:AOLE_RS17860
uniprot id: D8JHQ4
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

436717:AOLE RS07215
gene id: 436717:AOLE_RS07215
uniprot id: D8JHD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

436717:AOLE RS18305
gene id: 436717:AOLE_RS18305
uniprot id: D8JIC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

436717:AOLE RS00505
gene id: 436717:AOLE_RS00505
uniprot id: D8JKW0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

436717:AOLE RS04640
gene id: 436717:AOLE_RS04640
uniprot id: D8JEF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

436717:AOLE RS08610
gene id: 436717:AOLE_RS08610
uniprot id: D8JIX6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS07240
gene id: 436717:AOLE_RS07240
uniprot id: D8JHE4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS18250
gene id: 436717:AOLE_RS18250
uniprot id: D8JIB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

436717:AOLE RS02990
gene id: 436717:AOLE_RS02990
uniprot id: D8JNT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

436717:AOLE RS06335
gene id: 436717:AOLE_RS06335
uniprot id: D8JGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

436717:AOLE RS10345
gene id: 436717:AOLE_RS10345
uniprot id: D8JKC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

436717:AOLE RS17080
gene id: 436717:AOLE_RS17080
uniprot id: D8JGW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

436717:AOLE RS09335
gene id: 436717:AOLE_RS09335
uniprot id: D8JJQ8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

436717:AOLE RS19400
gene id: 436717:AOLE_RS19400
uniprot id: D8JJC4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

436717:AOLE RS00145
gene id: 436717:AOLE_RS00145
uniprot id: D8JKN7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS00495
gene id: 436717:AOLE_RS00495
uniprot id: D8JKV8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

436717:AOLE RS18385
gene id: 436717:AOLE_RS18385
uniprot id: D8JIE1
names: Similarity
messages: Belongs to the DapA family.

436717:AOLE RS03020
gene id: 436717:AOLE_RS03020
uniprot id: D8JNT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

436717:AOLE RS00435
gene id: 436717:AOLE_RS00435
uniprot id: D8JKU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

436717:AOLE RS13375
gene id: 436717:AOLE_RS13375
uniprot id: D8JNK7
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

436717:AOLE RS10905
gene id: 436717:AOLE_RS10905
uniprot id: D8JL22
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS19270
gene id: 436717:AOLE_RS19270
uniprot id: D8JJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

436717:AOLE RS00625
gene id: 436717:AOLE_RS00625
uniprot id: D8JKY4
names: Similarity
messages: Belongs to the allantoicase family.

436717:AOLE RS01680
gene id: 436717:AOLE_RS01680
uniprot id: D8JMB2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

436717:AOLE RS02210
gene id: 436717:AOLE_RS02210
uniprot id: D8JN05
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

436717:AOLE RS06180
gene id: 436717:AOLE_RS06180
uniprot id: D8JGE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

436717:AOLE RS19055
gene id: 436717:AOLE_RS19055
uniprot id: D8JJ59
names: Similarity
messages: Belongs to the citrate synthase family.

436717:AOLE RS15875
gene id: 436717:AOLE_RS15875
uniprot id: D8JFH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

436717:AOLE RS11950
gene id: 436717:AOLE_RS11950
uniprot id: D8JM15
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS14650
gene id: 436717:AOLE_RS14650
uniprot id: D8JE05
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

436717:AOLE RS14015
gene id: 436717:AOLE_RS14015
uniprot id: D8JPB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

436717:AOLE RS01070
gene id: 436717:AOLE_RS01070
uniprot id: D8JLK8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS07625
gene id: 436717:AOLE_RS07625
uniprot id: D8JHZ9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

436717:AOLE RS08695
gene id: 436717:AOLE_RS08695
uniprot id: D8JIZ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

436717:AOLE RS00535
gene id: 436717:AOLE_RS00535
uniprot id: D8JKW6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

436717:AOLE RS02105
gene id: 436717:AOLE_RS02105
uniprot id: D8JMY4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

436717:AOLE RS13015
gene id: 436717:AOLE_RS13015
uniprot id: D8JND6
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

436717:AOLE RS13700
gene id: 436717:AOLE_RS13700
uniprot id: D8JP53
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS16605
gene id: 436717:AOLE_RS16605
uniprot id: D8JG85
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

436717:AOLE RS19070
gene id: 436717:AOLE_RS19070
uniprot id: D8JJ62
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

436717:AOLE RS17620
gene id: 436717:AOLE_RS17620
uniprot id: D8JHK8
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

436717:AOLE RS01090
gene id: 436717:AOLE_RS01090
uniprot id: D8JLL2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

436717:AOLE RS17295
gene id: 436717:AOLE_RS17295
uniprot id: D8JH09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS07440
gene id: 436717:AOLE_RS07440
uniprot id: D8JHW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

436717:AOLE RS13915
gene id: 436717:AOLE_RS13915
uniprot id: D8JP97
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS02435
gene id: 436717:AOLE_RS02435
uniprot id: D8JN47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

436717:AOLE RS03810
gene id: 436717:AOLE_RS03810
uniprot id: D8JDK0
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

436717:AOLE RS18785
gene id: 436717:AOLE_RS18785
uniprot id: D8JIL9
names: Similarity
messages: Belongs to the BolA/IbaG family.

436717:AOLE RS16475
gene id: 436717:AOLE_RS16475
uniprot id: D8JG59
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

436717:AOLE RS15880
gene id: 436717:AOLE_RS15880
uniprot id: D8JFH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

436717:AOLE RS05430
gene id: 436717:AOLE_RS05430
uniprot id: D8JFM7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

436717:AOLE RS15870
gene id: 436717:AOLE_RS15870
uniprot id: D8JFG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

436717:AOLE RS00545
gene id: 436717:AOLE_RS00545
uniprot id: D8JKW8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS02870
gene id: 436717:AOLE_RS02870
uniprot id: D8JNQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS04135
gene id: 436717:AOLE_RS04135
uniprot id: D8JE47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

436717:AOLE RS11255
gene id: 436717:AOLE_RS11255
uniprot id: D8JL90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS03595
gene id: 436717:AOLE_RS03595
uniprot id: D8JDF6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS13575
gene id: 436717:AOLE_RS13575
uniprot id: D8JP26
names: Similarity
messages: Belongs to the aspartokinase family.

436717:AOLE RS07800
gene id: 436717:AOLE_RS07800
uniprot id: D8JI34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

436717:AOLE RS16795
gene id: 436717:AOLE_RS16795
uniprot id: D8JGC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

436717:AOLE RS09470
gene id: 436717:AOLE_RS09470
uniprot id: D8JJU8
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

436717:AOLE RS11595
gene id: 436717:AOLE_RS11595
uniprot id: D8JLU3
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

436717:AOLE RS16695
gene id: 436717:AOLE_RS16695
uniprot id: D8JGA3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

436717:AOLE RS00725
gene id: 436717:AOLE_RS00725
uniprot id: D8JLE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

436717:AOLE RS00220
gene id: 436717:AOLE_RS00220
uniprot id: D8JKQ2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS03140
gene id: 436717:AOLE_RS03140
uniprot id: D8JNW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

436717:AOLE RS05570
gene id: 436717:AOLE_RS05570
uniprot id: D8JFQ4
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

436717:AOLE RS03840
gene id: 436717:AOLE_RS03840
uniprot id: D8JDK7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

436717:AOLE RS09650
gene id: 436717:AOLE_RS09650
uniprot id: D8JJY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

436717:AOLE RS16010
gene id: 436717:AOLE_RS16010
uniprot id: D8JFJ7
names: Similarity
messages: Belongs to the darcynin family.

436717:AOLE RS05170
gene id: 436717:AOLE_RS05170
uniprot id: D8JF41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

436717:AOLE RS12085
gene id: 436717:AOLE_RS12085
uniprot id: D8JM41
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

436717:AOLE RS01985
gene id: 436717:AOLE_RS01985
uniprot id: D8JMH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

436717:AOLE RS19515
gene id: 436717:AOLE_RS19515
uniprot id: D8JJT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

436717:AOLE RS14315
gene id: 436717:AOLE_RS14315
uniprot id: D8JDT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

436717:AOLE RS00400
gene id: 436717:AOLE_RS00400
uniprot id: D8JKT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

436717:AOLE RS19510
gene id: 436717:AOLE_RS19510
uniprot id: D8JJT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

436717:AOLE RS14400
gene id: 436717:AOLE_RS14400
uniprot id: D8JDV5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

436717:AOLE RS13885
gene id: 436717:AOLE_RS13885
uniprot id: D8JP91
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

436717:AOLE RS17785
gene id: 436717:AOLE_RS17785
uniprot id: D8JHP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

436717:AOLE RS05300
gene id: 436717:AOLE_RS05300
uniprot id: D8JF69
names: Similarity
messages: Belongs to the pirin family.

436717:AOLE RS01325
gene id: 436717:AOLE_RS01325
uniprot id: D8JLQ8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

436717:AOLE RS06370
gene id: 436717:AOLE_RS06370
uniprot id: D8JGI5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

436717:AOLE RS10160
gene id: 436717:AOLE_RS10160
uniprot id: D8JK91
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

436717:AOLE RS08305
gene id: 436717:AOLE_RS08305
uniprot id: D8JIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

436717:AOLE RS15425
gene id: 436717:AOLE_RS15425
uniprot id: D8JEU5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS07465
gene id: 436717:AOLE_RS07465
uniprot id: D8JHW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

436717:AOLE RS03685
gene id: 436717:AOLE_RS03685
uniprot id: D8JDH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

436717:AOLE RS05860
gene id: 436717:AOLE_RS05860
uniprot id: D8JFW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

436717:AOLE RS10695
gene id: 436717:AOLE_RS10695
uniprot id: D8JKJ9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

436717:AOLE RS11520
gene id: 436717:AOLE_RS11520
uniprot id: D8JLS7
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS18035
gene id: 436717:AOLE_RS18035
uniprot id: D8JHT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

436717:AOLE RS16255
gene id: 436717:AOLE_RS16255
uniprot id: D8JG20
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

436717:AOLE RS17675
gene id: 436717:AOLE_RS17675
uniprot id: D8JHL9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

436717:AOLE RS15300
gene id: 436717:AOLE_RS15300
uniprot id: D8JES1
names: Similarity
messages: Belongs to the Rht family.

436717:AOLE RS06625
gene id: 436717:AOLE_RS06625
uniprot id: D8JGN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

436717:AOLE RS13540
gene id: 436717:AOLE_RS13540
uniprot id: D8JP19
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

436717:AOLE RS05770
gene id: 436717:AOLE_RS05770
uniprot id: D8JFU3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS14300
gene id: 436717:AOLE_RS14300
uniprot id: D8JDT4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS06255
gene id: 436717:AOLE_RS06255
uniprot id: D8JGG2
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS00415
gene id: 436717:AOLE_RS00415
uniprot id: D8JKU1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

436717:AOLE RS14370
gene id: 436717:AOLE_RS14370
uniprot id: D8JDU9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

436717:AOLE RS15650
gene id: 436717:AOLE_RS15650
uniprot id: D8JFC3
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

436717:AOLE RS15495
gene id: 436717:AOLE_RS15495
uniprot id: D8JF94
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

436717:AOLE RS16060
gene id: 436717:AOLE_RS16060
uniprot id: D8JFK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS01360
gene id: 436717:AOLE_RS01360
uniprot id: D8JM51
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

436717:AOLE RS08460
gene id: 436717:AOLE_RS08460
uniprot id: D8JIU6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

436717:AOLE RS03400
gene id: 436717:AOLE_RS03400
uniprot id: D8JDB9
names: Similarity
messages: Belongs to the peptidase C56 family.

436717:AOLE RS03445
gene id: 436717:AOLE_RS03445
uniprot id: D8JDC9
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

436717:AOLE RS14225
gene id: 436717:AOLE_RS14225
uniprot id: D8JDR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

436717:AOLE RS19520
gene id: 436717:AOLE_RS19520
uniprot id: D8JJT4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS19475
gene id: 436717:AOLE_RS19475
uniprot id: D8JJD9
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

436717:AOLE RS04255
gene id: 436717:AOLE_RS04255
uniprot id: D8JE72
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

436717:AOLE RS05075
gene id: 436717:AOLE_RS05075
uniprot id: D8JF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

436717:AOLE RS13780
gene id: 436717:AOLE_RS13780
uniprot id: D8JP69
names: Similarity
messages: Belongs to the tannase family.

436717:AOLE RS17365
gene id: 436717:AOLE_RS17365
uniprot id: D8JH23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

436717:AOLE RS13750
gene id: 436717:AOLE_RS13750
uniprot id: D8JP63
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

436717:AOLE RS08570
gene id: 436717:AOLE_RS08570
uniprot id: D8JIW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS17820
gene id: 436717:AOLE_RS17820
uniprot id: D8JHP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS10470
gene id: 436717:AOLE_RS10470
uniprot id: D8JKF4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS17180
gene id: 436717:AOLE_RS17180
uniprot id: D8JGY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

436717:AOLE RS14755
gene id: 436717:AOLE_RS14755
uniprot id: D8JE26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

436717:AOLE RS10640
gene id: 436717:AOLE_RS10640
uniprot id: D8JKI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

436717:AOLE RS12785
gene id: 436717:AOLE_RS12785
uniprot id: D8JN90
names: Subcellular Location Annotation
messages: Cytoplasm

436717:AOLE RS04390
gene id: 436717:AOLE_RS04390
uniprot id: D8JEA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

436717:AOLE RS15245
gene id: 436717:AOLE_RS15245
uniprot id: D8JEQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

436717:AOLE RS12430
gene id: 436717:AOLE_RS12430
uniprot id: D8JMP5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

436717:AOLE RS02215
gene id: 436717:AOLE_RS02215
uniprot id: D8JN06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

436717:AOLE RS07820
gene id: 436717:AOLE_RS07820
uniprot id: D8JI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS14285
gene id: 436717:AOLE_RS14285
uniprot id: D8JDT1
names: Cofactor
messages: Can also use Mn(2+) ion.

436717:AOLE RS07005
gene id: 436717:AOLE_RS07005
uniprot id: D8JH96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

436717:AOLE RS15200
gene id: 436717:AOLE_RS15200
uniprot id: D8JEQ0
names: Similarity
messages: Belongs to the GSP E family.

436717:AOLE RS09740
gene id: 436717:AOLE_RS09740
uniprot id: D8JK03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

436717:AOLE RS04220
gene id: 436717:AOLE_RS04220
uniprot id: D8JE65
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

436717:AOLE RS17185
gene id: 436717:AOLE_RS17185
uniprot id: D8JGY7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

436717:AOLE RS15675
gene id: 436717:AOLE_RS15675
uniprot id: D8JFC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS15405
gene id: 436717:AOLE_RS15405
uniprot id: D8JEU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. CntA subfamily.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of an oxygenase subunit and a reductase subunit.
messages: Converts carnitine to trimethylamine and malic semialdehyde.

436717:AOLE RS16500
gene id: 436717:AOLE_RS16500
uniprot id: D8JG64
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

436717:AOLE RS00730
gene id: 436717:AOLE_RS00730
uniprot id: D8JLE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

436717:AOLE RS17275
gene id: 436717:AOLE_RS17275
uniprot id: D8JH05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

436717:AOLE RS19340
gene id: 436717:AOLE_RS19340
uniprot id: D8JJB7
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS02115
gene id: 436717:AOLE_RS02115
uniprot id: D8JMY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

436717:AOLE RS14675
gene id: 436717:AOLE_RS14675
uniprot id: D8JE10
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

436717:AOLE RS06450
gene id: 436717:AOLE_RS06450
uniprot id: D8JGK0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

436717:AOLE RS02185
gene id: 436717:AOLE_RS02185
uniprot id: D8JN00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

436717:AOLE RS04275
gene id: 436717:AOLE_RS04275
uniprot id: D8JE77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS19505
gene id: 436717:AOLE_RS19505
uniprot id: D8JJT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

436717:AOLE RS13370
gene id: 436717:AOLE_RS13370
uniprot id: D8JNK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

436717:AOLE RS07320
gene id: 436717:AOLE_RS07320
uniprot id: D8JHG1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

436717:AOLE RS03765
gene id: 436717:AOLE_RS03765
uniprot id: D8JDJ1
names: Similarity
messages: Belongs to the UPF0250 family.

436717:AOLE RS03570
gene id: 436717:AOLE_RS03570
uniprot id: D8JDF1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS16400
gene id: 436717:AOLE_RS16400
uniprot id: D8JG44
names: Similarity
messages: Belongs to the OsmC/Ohr family.

436717:AOLE RS01610
gene id: 436717:AOLE_RS01610
uniprot id: D8JM97
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

436717:AOLE RS03065
gene id: 436717:AOLE_RS03065
uniprot id: D8JNU7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

436717:AOLE RS16940
gene id: 436717:AOLE_RS16940
uniprot id: D8JGT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

436717:AOLE RS10025
gene id: 436717:AOLE_RS10025
uniprot id: D8JK63
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

436717:AOLE RS04210
gene id: 436717:AOLE_RS04210
uniprot id: D8JE63
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS15605
gene id: 436717:AOLE_RS15605
uniprot id: D8JFB4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

436717:AOLE RS04760
gene id: 436717:AOLE_RS04760
uniprot id: D8JEV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

436717:AOLE RS17055
gene id: 436717:AOLE_RS17055
uniprot id: D8JGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

436717:AOLE RS19320
gene id: 436717:AOLE_RS19320
uniprot id: D8JJB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS10770
gene id: 436717:AOLE_RS10770
uniprot id: D8JKZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

436717:AOLE RS06100
gene id: 436717:AOLE_RS06100
uniprot id: D8JGD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

436717:AOLE RS04795
gene id: 436717:AOLE_RS04795
uniprot id: D8JEW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS11310
gene id: 436717:AOLE_RS11310
uniprot id: D8JLA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS02410
gene id: 436717:AOLE_RS02410
uniprot id: D8JN42
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

436717:AOLE RS02130
gene id: 436717:AOLE_RS02130
uniprot id: D8JMY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

436717:AOLE RS05915
gene id: 436717:AOLE_RS05915
uniprot id: D8JFX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

436717:AOLE RS15885
gene id: 436717:AOLE_RS15885
uniprot id: D8JFH2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

436717:AOLE RS17445
gene id: 436717:AOLE_RS17445
uniprot id: D8JH39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

436717:AOLE RS14720
gene id: 436717:AOLE_RS14720
uniprot id: D8JE19
names: Cofactor
messages: Binds 1 zinc ion per subunit.

436717:AOLE RS17770
gene id: 436717:AOLE_RS17770
uniprot id: D8JHN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

436717:AOLE RS14000
gene id: 436717:AOLE_RS14000
uniprot id: D8JPB4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

436717:AOLE RS08710
gene id: 436717:AOLE_RS08710
uniprot id: D8JIZ6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

436717:AOLE RS14045
gene id: 436717:AOLE_RS14045
uniprot id: D8JPC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS11140
gene id: 436717:AOLE_RS11140
uniprot id: D8JL69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

436717:AOLE RS08390
gene id: 436717:AOLE_RS08390
uniprot id: D8JIT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

436717:AOLE RS03365
gene id: 436717:AOLE_RS03365
uniprot id: D8JP02
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS16140
gene id: 436717:AOLE_RS16140
uniprot id: D8JG01
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS10140
gene id: 436717:AOLE_RS10140
uniprot id: D8JK86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS15365
gene id: 436717:AOLE_RS15365
uniprot id: D8JET4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

436717:AOLE RS00115
gene id: 436717:AOLE_RS00115
uniprot id: D8JKN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

436717:AOLE RS09920
gene id: 436717:AOLE_RS09920
uniprot id: D8JK42
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

436717:AOLE RS16815
gene id: 436717:AOLE_RS16815
uniprot id: D8JGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

436717:AOLE RS18560
gene id: 436717:AOLE_RS18560
uniprot id: D8JIH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS06615
gene id: 436717:AOLE_RS06615
uniprot id: D8JGN3
names: Similarity
messages: Belongs to the glutamine synthetase family.

436717:AOLE RS16320
gene id: 436717:AOLE_RS16320
uniprot id: D8JG33
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

436717:AOLE RS10825
gene id: 436717:AOLE_RS10825
uniprot id: D8JL06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

436717:AOLE RS10950
gene id: 436717:AOLE_RS10950
uniprot id: D8JL31
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

436717:AOLE RS15150
gene id: 436717:AOLE_RS15150
uniprot id: D8JEP0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

436717:AOLE RS07655
gene id: 436717:AOLE_RS07655
uniprot id: D8JI05
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

436717:AOLE RS01440
gene id: 436717:AOLE_RS01440
uniprot id: D8JM65
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS00225
gene id: 436717:AOLE_RS00225
uniprot id: D8JKQ3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

436717:AOLE RS18650
gene id: 436717:AOLE_RS18650
uniprot id: D8JIJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

436717:AOLE RS08690
gene id: 436717:AOLE_RS08690
uniprot id: D8JIZ2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

436717:AOLE RS08720
gene id: 436717:AOLE_RS08720
uniprot id: D8JIZ8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

436717:AOLE RS04125
gene id: 436717:AOLE_RS04125
uniprot id: D8JE44
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS16090
gene id: 436717:AOLE_RS16090
uniprot id: D8JFL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS01875
gene id: 436717:AOLE_RS01875
uniprot id: D8JMF2
names: Similarity
messages: Belongs to the peptidase S8 family.

436717:AOLE RS11525
gene id: 436717:AOLE_RS11525
uniprot id: D8JLS8
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

436717:AOLE RS03950
gene id: 436717:AOLE_RS03950
uniprot id: D8JDM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

436717:AOLE RS11630
gene id: 436717:AOLE_RS11630
uniprot id: D8JLV0
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS11430
gene id: 436717:AOLE_RS11430
uniprot id: D8JLC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

436717:AOLE RS14065
gene id: 436717:AOLE_RS14065
uniprot id: D8JPC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

436717:AOLE RS13645
gene id: 436717:AOLE_RS13645
uniprot id: D8JP42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS10865
gene id: 436717:AOLE_RS10865
uniprot id: D8JL14
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

436717:AOLE RS13020
gene id: 436717:AOLE_RS13020
uniprot id: D8JND7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

436717:AOLE RS09910
gene id: 436717:AOLE_RS09910
uniprot id: D8JK39
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

436717:AOLE RS14845
gene id: 436717:AOLE_RS14845
uniprot id: D8JEH8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

436717:AOLE RS15400
gene id: 436717:AOLE_RS15400
uniprot id: D8JEU0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

436717:AOLE RS06970
gene id: 436717:AOLE_RS06970
uniprot id: D8JH88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS12325
gene id: 436717:AOLE_RS12325
uniprot id: D8JMM3
names: Similarity
messages: Belongs to the VgrG protein family.

436717:AOLE RS08340
gene id: 436717:AOLE_RS08340
uniprot id: D8JIS1
names: Similarity
messages: Belongs to the peptidase M16 family.

436717:AOLE RS14415
gene id: 436717:AOLE_RS14415
uniprot id: D8JDV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS17740
gene id: 436717:AOLE_RS17740
uniprot id: D8JHN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

436717:AOLE RS07135
gene id: 436717:AOLE_RS07135
uniprot id: D8JHC3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

436717:AOLE RS15340
gene id: 436717:AOLE_RS15340
uniprot id: D8JES9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

436717:AOLE RS15510
gene id: 436717:AOLE_RS15510
uniprot id: D8JF95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

436717:AOLE RS11295
gene id: 436717:AOLE_RS11295
uniprot id: D8JL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

436717:AOLE RS01455
gene id: 436717:AOLE_RS01455
uniprot id: D8JM66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

436717:AOLE RS15290
gene id: 436717:AOLE_RS15290
uniprot id: D8JER9
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

436717:AOLE RS16480
gene id: 436717:AOLE_RS16480
uniprot id: D8JG60
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

436717:AOLE RS16770
gene id: 436717:AOLE_RS16770
uniprot id: D8JGB8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

436717:AOLE RS18335
gene id: 436717:AOLE_RS18335
uniprot id: D8JID0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

436717:AOLE RS03405
gene id: 436717:AOLE_RS03405
uniprot id: D8JDC0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

436717:AOLE RS12955
gene id: 436717:AOLE_RS12955
uniprot id: D8JNC4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS18025
gene id: 436717:AOLE_RS18025
uniprot id: D8JHT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

436717:AOLE RS18745
gene id: 436717:AOLE_RS18745
uniprot id: D8JIL1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

436717:AOLE RS03485
gene id: 436717:AOLE_RS03485
uniprot id: D8JDD6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS08085
gene id: 436717:AOLE_RS08085
uniprot id: D8JI92
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

436717:AOLE RS17545
gene id: 436717:AOLE_RS17545
uniprot id: D8JHJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

436717:AOLE RS18620
gene id: 436717:AOLE_RS18620
uniprot id: D8JII5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

436717:AOLE RS00055
gene id: 436717:AOLE_RS00055
uniprot id: D8JKM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

436717:AOLE RS11260
gene id: 436717:AOLE_RS11260
uniprot id: D8JL91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

436717:AOLE RS19305
gene id: 436717:AOLE_RS19305
uniprot id: D8JJB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

436717:AOLE RS12740
gene id: 436717:AOLE_RS12740
uniprot id: D8JMV8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS04810
gene id: 436717:AOLE_RS04810
uniprot id: D8JEW8
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

436717:AOLE RS16340
gene id: 436717:AOLE_RS16340
uniprot id: D8JG37
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

436717:AOLE RS17335
gene id: 436717:AOLE_RS17335
uniprot id: D8JH17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

436717:AOLE RS01595
gene id: 436717:AOLE_RS01595
uniprot id: D8JM94
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

436717:AOLE RS04620
gene id: 436717:AOLE_RS04620
uniprot id: D8JEE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

436717:AOLE RS07040
gene id: 436717:AOLE_RS07040
uniprot id: D8JHA3
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

436717:AOLE RS11265
gene id: 436717:AOLE_RS11265
uniprot id: D8JL92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

436717:AOLE RS06235
gene id: 436717:AOLE_RS06235
uniprot id: D8JGF8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

436717:AOLE RS08230
gene id: 436717:AOLE_RS08230
uniprot id: D8JIQ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS16240
gene id: 436717:AOLE_RS16240
uniprot id: D8JG17
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

436717:AOLE RS02600
gene id: 436717:AOLE_RS02600
uniprot id: D8JN75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

436717:AOLE RS05000
gene id: 436717:AOLE_RS05000
uniprot id: D8JF07
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS05375
gene id: 436717:AOLE_RS05375
uniprot id: D8JF84
names: Similarity
messages: Belongs to the peptidase M24B family.

436717:AOLE RS14505
gene id: 436717:AOLE_RS14505
uniprot id: D8JDX6
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS03865
gene id: 436717:AOLE_RS03865
uniprot id: D8JDL2
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS16810
gene id: 436717:AOLE_RS16810
uniprot id: D8JGC6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

436717:AOLE RS08615
gene id: 436717:AOLE_RS08615
uniprot id: D8JIX7
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

436717:AOLE RS06535
gene id: 436717:AOLE_RS06535
uniprot id: D8JGL7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

436717:AOLE RS07450
gene id: 436717:AOLE_RS07450
uniprot id: D8JHW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

436717:AOLE RS04420
gene id: 436717:AOLE_RS04420
uniprot id: D8JEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

436717:AOLE RS15795
gene id: 436717:AOLE_RS15795
uniprot id: D8JFF3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

436717:AOLE RS08465
gene id: 436717:AOLE_RS08465
uniprot id: D8JIU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS07165
gene id: 436717:AOLE_RS07165
uniprot id: D8JHC9
names: Similarity
messages: Belongs to the glutamate synthase family.

436717:AOLE RS14640
gene id: 436717:AOLE_RS14640
uniprot id: D8JE03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS17610
gene id: 436717:AOLE_RS17610
uniprot id: D8JHK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

436717:AOLE RS17535
gene id: 436717:AOLE_RS17535
uniprot id: D8JHJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

436717:AOLE RS16195
gene id: 436717:AOLE_RS16195
uniprot id: D8JG08
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

436717:AOLE RS15030
gene id: 436717:AOLE_RS15030
uniprot id: D8JEL5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

436717:AOLE RS17840
gene id: 436717:AOLE_RS17840
uniprot id: D8JHQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

436717:AOLE RS17110
gene id: 436717:AOLE_RS17110
uniprot id: D8JGX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

436717:AOLE RS15900
gene id: 436717:AOLE_RS15900
uniprot id: D8JFH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

436717:AOLE RS04655
gene id: 436717:AOLE_RS04655
uniprot id: D8JEF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

436717:AOLE RS19315
gene id: 436717:AOLE_RS19315
uniprot id: D8JJB2
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

436717:AOLE RS02575
gene id: 436717:AOLE_RS02575
uniprot id: D8JN70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

436717:AOLE RS11035
gene id: 436717:AOLE_RS11035
uniprot id: D8JL48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS03630
gene id: 436717:AOLE_RS03630
uniprot id: D8JDG3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS19345
gene id: 436717:AOLE_RS19345
uniprot id: D8JJB8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

436717:AOLE RS00585
gene id: 436717:AOLE_RS00585
uniprot id: D8JKX6
names: Similarity
messages: Belongs to the VgrG protein family.

436717:AOLE RS19530
gene id: 436717:AOLE_RS19530
uniprot id: D8JJT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS13250
gene id: 436717:AOLE_RS13250
uniprot id: D8JNI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

436717:AOLE RS05515
gene id: 436717:AOLE_RS05515
uniprot id: D8JFP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

436717:AOLE RS17415
gene id: 436717:AOLE_RS17415
uniprot id: D8JH33
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS06605
gene id: 436717:AOLE_RS06605
uniprot id: D8JGN1
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS17200
gene id: 436717:AOLE_RS17200
uniprot id: D8JGZ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

436717:AOLE RS04020
gene id: 436717:AOLE_RS04020
uniprot id: D8JDN7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

436717:AOLE RS14050
gene id: 436717:AOLE_RS14050
uniprot id: D8JPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS15750
gene id: 436717:AOLE_RS15750
uniprot id: D8JFE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

436717:AOLE RS14115
gene id: 436717:AOLE_RS14115
uniprot id: D8JPD7
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS05745
gene id: 436717:AOLE_RS05745
uniprot id: D8JFT8
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

436717:AOLE RS16980
gene id: 436717:AOLE_RS16980
uniprot id: D8JGU6
names: Similarity
messages: Belongs to the peptidase S41A family.

436717:AOLE RS01955
gene id: 436717:AOLE_RS01955
uniprot id: D8JMG9
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS08540
gene id: 436717:AOLE_RS08540
uniprot id: D8JIW2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

436717:AOLE RS07475
gene id: 436717:AOLE_RS07475
uniprot id: D8JHW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

436717:AOLE RS05785
gene id: 436717:AOLE_RS05785
uniprot id: D8JFU6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

436717:AOLE RS19525
gene id: 436717:AOLE_RS19525
uniprot id: D8JJT5
names: Similarity
messages: Belongs to the FrmR/RcnR family.

436717:AOLE RS11025
gene id: 436717:AOLE_RS11025
uniprot id: D8JL46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

436717:AOLE RS17015
gene id: 436717:AOLE_RS17015
uniprot id: D8JGV3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

436717:AOLE RS13090
gene id: 436717:AOLE_RS13090
uniprot id: D8JNF1
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS13615
gene id: 436717:AOLE_RS13615
uniprot id: D8JP35
names: Similarity
messages: Belongs to the pirin family.

436717:AOLE RS09960
gene id: 436717:AOLE_RS09960
uniprot id: D8JK50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

436717:AOLE RS14185
gene id: 436717:AOLE_RS14185
uniprot id: D8JDR0
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

436717:AOLE RS11625
gene id: 436717:AOLE_RS11625
uniprot id: D8JLU9
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS16760
gene id: 436717:AOLE_RS16760
uniprot id: D8JGB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

436717:AOLE RS17655
gene id: 436717:AOLE_RS17655
uniprot id: D8JHL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

436717:AOLE RS02135
gene id: 436717:AOLE_RS02135
uniprot id: D8JMZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

436717:AOLE RS15575
gene id: 436717:AOLE_RS15575
uniprot id: D8JFA8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

436717:AOLE RS18655
gene id: 436717:AOLE_RS18655
uniprot id: D8JIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

436717:AOLE RS10565
gene id: 436717:AOLE_RS10565
uniprot id: D8JKH3
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

436717:AOLE RS17405
gene id: 436717:AOLE_RS17405
uniprot id: D8JH31
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

436717:AOLE RS13765
gene id: 436717:AOLE_RS13765
uniprot id: D8JP66
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

436717:AOLE RS18720
gene id: 436717:AOLE_RS18720
uniprot id: D8JIK6
names: Similarity
messages: Belongs to the pirin family.

436717:AOLE RS01520
gene id: 436717:AOLE_RS01520
uniprot id: D8JM79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

436717:AOLE RS14350
gene id: 436717:AOLE_RS14350
uniprot id: D8JDU5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

436717:AOLE RS09795
gene id: 436717:AOLE_RS09795
uniprot id: D8JK14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS10150
gene id: 436717:AOLE_RS10150
uniprot id: D8JK89
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

436717:AOLE RS12095
gene id: 436717:AOLE_RS12095
uniprot id: D8JM43
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS08245
gene id: 436717:AOLE_RS08245
uniprot id: D8JIQ3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

436717:AOLE RS06470
gene id: 436717:AOLE_RS06470
uniprot id: D8JGK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS19430
gene id: 436717:AOLE_RS19430
uniprot id: D8JJD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

436717:AOLE RS03620
gene id: 436717:AOLE_RS03620
uniprot id: D8JDG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

436717:AOLE RS12840
gene id: 436717:AOLE_RS12840
uniprot id: D8JNA2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS00815
gene id: 436717:AOLE_RS00815
uniprot id: D8JLF8
names: Similarity
messages: Belongs to the RecJ family.

436717:AOLE RS05630
gene id: 436717:AOLE_RS05630
uniprot id: D8JFR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

436717:AOLE RS12625
gene id: 436717:AOLE_RS12625
uniprot id: D8JMT5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS13195
gene id: 436717:AOLE_RS13195
uniprot id: D8JNH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

436717:AOLE RS02515
gene id: 436717:AOLE_RS02515
uniprot id: D8JN58
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

436717:AOLE RS06385
gene id: 436717:AOLE_RS06385
uniprot id: D8JGI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

436717:AOLE RS01405
gene id: 436717:AOLE_RS01405
uniprot id: D8JM60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

436717:AOLE RS10780
gene id: 436717:AOLE_RS10780
uniprot id: D8JKZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

436717:AOLE RS04425
gene id: 436717:AOLE_RS04425
uniprot id: D8JEA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

436717:AOLE RS14480
gene id: 436717:AOLE_RS14480
uniprot id: D8JDX1
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS16640
gene id: 436717:AOLE_RS16640
uniprot id: D8JG92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

436717:AOLE RS11545
gene id: 436717:AOLE_RS11545
uniprot id: D8JLT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

436717:AOLE RS02920
gene id: 436717:AOLE_RS02920
uniprot id: D8JNR8
names: Similarity
messages: Belongs to the YkuD family.

436717:AOLE RS09730
gene id: 436717:AOLE_RS09730
uniprot id: D8JK01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

436717:AOLE RS19245
gene id: 436717:AOLE_RS19245
uniprot id: D8JJ98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

436717:AOLE RS10965
gene id: 436717:AOLE_RS10965
uniprot id: D8JL34
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

436717:AOLE RS04345
gene id: 436717:AOLE_RS04345
uniprot id: D8JE91
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS08495
gene id: 436717:AOLE_RS08495
uniprot id: D8JIV3
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

436717:AOLE RS11395
gene id: 436717:AOLE_RS11395
uniprot id: D8JLB9
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS06200
gene id: 436717:AOLE_RS06200
uniprot id: D8JGF1
names: Similarity
messages: Belongs to the CFA/CMAS family.

436717:AOLE RS02075
gene id: 436717:AOLE_RS02075
uniprot id: D8JMX8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS18430
gene id: 436717:AOLE_RS18430
uniprot id: D8JIF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

436717:AOLE RS09760
gene id: 436717:AOLE_RS09760
uniprot id: D8JK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS06755
gene id: 436717:AOLE_RS06755
uniprot id: D8JGR1
names: Similarity
messages: Belongs to the nitroreductase family.

436717:AOLE RS00785
gene id: 436717:AOLE_RS00785
uniprot id: D8JLF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

436717:AOLE RS03540
gene id: 436717:AOLE_RS03540
uniprot id: D8JDE6
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS05850
gene id: 436717:AOLE_RS05850
uniprot id: D8JFV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

436717:AOLE RS02035
gene id: 436717:AOLE_RS02035
uniprot id: D8JMX1
names: Similarity
messages: Belongs to the LOG family.

436717:AOLE RS13485
gene id: 436717:AOLE_RS13485
uniprot id: D8JP08
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

436717:AOLE RS04525
gene id: 436717:AOLE_RS04525
uniprot id: D8JEC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

436717:AOLE RS12900
gene id: 436717:AOLE_RS12900
uniprot id: D8JNB3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

436717:AOLE RS17350
gene id: 436717:AOLE_RS17350
uniprot id: D8JH20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS02140
gene id: 436717:AOLE_RS02140
uniprot id: D8JMZ1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

436717:AOLE RS04630
gene id: 436717:AOLE_RS04630
uniprot id: D8JEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

436717:AOLE RS02480
gene id: 436717:AOLE_RS02480
uniprot id: D8JN51
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS16405
gene id: 436717:AOLE_RS16405
uniprot id: D8JG45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

436717:AOLE RS11605
gene id: 436717:AOLE_RS11605
uniprot id: D8JLU5
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS10310
gene id: 436717:AOLE_RS10310
uniprot id: D8JKC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

436717:AOLE RS01630
gene id: 436717:AOLE_RS01630
uniprot id: D8JMA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

436717:AOLE RS01980
gene id: 436717:AOLE_RS01980
uniprot id: D8JMH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

436717:AOLE RS06485
gene id: 436717:AOLE_RS06485
uniprot id: D8JGK7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

436717:AOLE RS06425
gene id: 436717:AOLE_RS06425
uniprot id: D8JGJ5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

436717:AOLE RS03830
gene id: 436717:AOLE_RS03830
uniprot id: D8JDK5
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

436717:AOLE RS11690
gene id: 436717:AOLE_RS11690
uniprot id: D8JLW2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

436717:AOLE RS10645
gene id: 436717:AOLE_RS10645
uniprot id: D8JKI9
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

436717:AOLE RS13035
gene id: 436717:AOLE_RS13035
uniprot id: D8JNE0
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

436717:AOLE RS05865
gene id: 436717:AOLE_RS05865
uniprot id: D8JFW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

436717:AOLE RS10445
gene id: 436717:AOLE_RS10445
uniprot id: D8JKE9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS18040
gene id: 436717:AOLE_RS18040
uniprot id: D8JHU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

436717:AOLE RS10255
gene id: 436717:AOLE_RS10255
uniprot id: D8JKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS11410
gene id: 436717:AOLE_RS11410
uniprot id: D8JLC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS01210
gene id: 436717:AOLE_RS01210
uniprot id: D8JLN6
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

436717:AOLE RS16190
gene id: 436717:AOLE_RS16190
uniprot id: D8JG07
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

436717:AOLE RS03220
gene id: 436717:AOLE_RS03220
uniprot id: D8JNX9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS07140
gene id: 436717:AOLE_RS07140
uniprot id: D8JHC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

436717:AOLE RS18625
gene id: 436717:AOLE_RS18625
uniprot id: D8JII6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

436717:AOLE RS18295
gene id: 436717:AOLE_RS18295
uniprot id: D8JIC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

436717:AOLE RS13600
gene id: 436717:AOLE_RS13600
uniprot id: D8JP31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

436717:AOLE RS18400
gene id: 436717:AOLE_RS18400
uniprot id: D8JIE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

436717:AOLE RS06270
gene id: 436717:AOLE_RS06270
uniprot id: D8JGG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

436717:AOLE RS05470
gene id: 436717:AOLE_RS05470
uniprot id: D8JFN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

436717:AOLE RS15305
gene id: 436717:AOLE_RS15305
uniprot id: D8JES2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

436717:AOLE RS19540
gene id: 436717:AOLE_RS19540
uniprot id: D8JJT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

436717:AOLE RS08275
gene id: 436717:AOLE_RS08275
uniprot id: D8JIQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

436717:AOLE RS10755
gene id: 436717:AOLE_RS10755
uniprot id: D8JKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

436717:AOLE RS05465
gene id: 436717:AOLE_RS05465
uniprot id: D8JFN4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

436717:AOLE RS08160
gene id: 436717:AOLE_RS08160
uniprot id: D8JIN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

436717:AOLE RS07895
gene id: 436717:AOLE_RS07895
uniprot id: D8JI54
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS10010
gene id: 436717:AOLE_RS10010
uniprot id: D8JK60
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

436717:AOLE RS06055
gene id: 436717:AOLE_RS06055
uniprot id: D8JFZ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS08310
gene id: 436717:AOLE_RS08310
uniprot id: D8JIR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS03135
gene id: 436717:AOLE_RS03135
uniprot id: D8JNW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

436717:AOLE RS17265
gene id: 436717:AOLE_RS17265
uniprot id: D8JH03
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

436717:AOLE RS00020
gene id: 436717:AOLE_RS00020
uniprot id: D8JKL7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

436717:AOLE RS08345
gene id: 436717:AOLE_RS08345
uniprot id: D8JIS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

436717:AOLE RS17505
gene id: 436717:AOLE_RS17505
uniprot id: D8JHI5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

436717:AOLE RS15845
gene id: 436717:AOLE_RS15845
uniprot id: D8JFG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

436717:AOLE RS10525
gene id: 436717:AOLE_RS10525
uniprot id: D8JKG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

436717:AOLE RS11360
gene id: 436717:AOLE_RS11360
uniprot id: D8JLB2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

436717:AOLE RS10285
gene id: 436717:AOLE_RS10285
uniprot id: D8JKB6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS14795
gene id: 436717:AOLE_RS14795
uniprot id: D8JEG8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS18200
gene id: 436717:AOLE_RS18200
uniprot id: D8JIA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

436717:AOLE RS10590
gene id: 436717:AOLE_RS10590
uniprot id: D8JKH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS04050
gene id: 436717:AOLE_RS04050
uniprot id: D8JDP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

436717:AOLE RS07435
gene id: 436717:AOLE_RS07435
uniprot id: D8JHW1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS11955
gene id: 436717:AOLE_RS11955
uniprot id: D8JM16
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

436717:AOLE RS13040
gene id: 436717:AOLE_RS13040
uniprot id: D8JNE1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

436717:AOLE RS03790
gene id: 436717:AOLE_RS03790
uniprot id: D8JDJ6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

436717:AOLE RS03820
gene id: 436717:AOLE_RS03820
uniprot id: D8JDK2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

436717:AOLE RS03270
gene id: 436717:AOLE_RS03270
uniprot id: D8JNY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

436717:AOLE RS04025
gene id: 436717:AOLE_RS04025
uniprot id: D8JDN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

436717:AOLE RS15655
gene id: 436717:AOLE_RS15655
uniprot id: D8JFC4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS07400
gene id: 436717:AOLE_RS07400
uniprot id: D8JHH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS01245
gene id: 436717:AOLE_RS01245
uniprot id: D8JLP3
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

436717:AOLE RS05820
gene id: 436717:AOLE_RS05820
uniprot id: D8JFV2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

436717:AOLE RS12495
gene id: 436717:AOLE_RS12495
uniprot id: D8JMQ8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS11735
gene id: 436717:AOLE_RS11735
uniprot id: D8JLX1
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS09180
gene id: 436717:AOLE_RS09180
uniprot id: D8JJM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS00740
gene id: 436717:AOLE_RS00740
uniprot id: D8JLE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

436717:AOLE RS15610
gene id: 436717:AOLE_RS15610
uniprot id: D8JFB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS16585
gene id: 436717:AOLE_RS16585
uniprot id: D8JG81
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS18510
gene id: 436717:AOLE_RS18510
uniprot id: D8JIG7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

436717:AOLE RS18900
gene id: 436717:AOLE_RS18900
uniprot id: D8JJ26
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS04735
gene id: 436717:AOLE_RS04735
uniprot id: D8JEV3
names: Similarity
messages: Belongs to the Gfa family.

436717:AOLE RS09485
gene id: 436717:AOLE_RS09485
uniprot id: D8JJV1
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

436717:AOLE RS02720
gene id: 436717:AOLE_RS02720
uniprot id: D8JNM9
names: Similarity
messages: Belongs to the YciI family.

436717:AOLE RS05310
gene id: 436717:AOLE_RS05310
uniprot id: D8JF71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS17060
gene id: 436717:AOLE_RS17060
uniprot id: D8JGW2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

436717:AOLE RS08535
gene id: 436717:AOLE_RS08535
uniprot id: D8JIW1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

436717:AOLE RS12060
gene id: 436717:AOLE_RS12060
uniprot id: D8JM36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

436717:AOLE RS17250
gene id: 436717:AOLE_RS17250
uniprot id: D8JH00
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

436717:AOLE RS01550
gene id: 436717:AOLE_RS01550
uniprot id: D8JM85
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

436717:AOLE RS14340
gene id: 436717:AOLE_RS14340
uniprot id: D8JDU3
names: Similarity
messages: Belongs to the AHA1 family.

436717:AOLE RS10995
gene id: 436717:AOLE_RS10995
uniprot id: D8JL40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

436717:AOLE RS00575
gene id: 436717:AOLE_RS00575
uniprot id: D8JKX4
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

436717:AOLE RS16925
gene id: 436717:AOLE_RS16925
uniprot id: D8JGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

436717:AOLE RS02160
gene id: 436717:AOLE_RS02160
uniprot id: D8JMZ5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

436717:AOLE RS13210
gene id: 436717:AOLE_RS13210
uniprot id: D8JNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

436717:AOLE RS12130
gene id: 436717:AOLE_RS12130
uniprot id: D8JMI3
names: Similarity
messages: Belongs to the proline racemase family.

436717:AOLE RS01775
gene id: 436717:AOLE_RS01775
uniprot id: D8JMD2
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS07445
gene id: 436717:AOLE_RS07445
uniprot id: D8JHW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

436717:AOLE RS14785
gene id: 436717:AOLE_RS14785
uniprot id: D8JE32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS18215
gene id: 436717:AOLE_RS18215
uniprot id: D8JIA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

436717:AOLE RS03670
gene id: 436717:AOLE_RS03670
uniprot id: D8JDH1
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS17195
gene id: 436717:AOLE_RS17195
uniprot id: D8JGY9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

436717:AOLE RS02945
gene id: 436717:AOLE_RS02945
uniprot id: D8JNS3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

436717:AOLE RS16920
gene id: 436717:AOLE_RS16920
uniprot id: D8JGT4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

436717:AOLE RS03015
gene id: 436717:AOLE_RS03015
uniprot id: D8JNT7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

436717:AOLE RS17745
gene id: 436717:AOLE_RS17745
uniprot id: D8JHN3
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS15625
gene id: 436717:AOLE_RS15625
uniprot id: D8JFB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS09980
gene id: 436717:AOLE_RS09980
uniprot id: D8JK54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

436717:AOLE RS06710
gene id: 436717:AOLE_RS06710
uniprot id: D8JGQ2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

436717:AOLE RS15800
gene id: 436717:AOLE_RS15800
uniprot id: D8JFF4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

436717:AOLE RS08765
gene id: 436717:AOLE_RS08765
uniprot id: D8JJ07
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

436717:AOLE RS18170
gene id: 436717:AOLE_RS18170
uniprot id: D8JI98
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

436717:AOLE RS10195
gene id: 436717:AOLE_RS10195
uniprot id: D8JK98
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS00770
gene id: 436717:AOLE_RS00770
uniprot id: D8JLE9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

436717:AOLE RS06795
gene id: 436717:AOLE_RS06795
uniprot id: D8JH53
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS05895
gene id: 436717:AOLE_RS05895
uniprot id: D8JFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

436717:AOLE RS16960
gene id: 436717:AOLE_RS16960
uniprot id: D8JGU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

436717:AOLE RS15935
gene id: 436717:AOLE_RS15935
uniprot id: D8JFI2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

436717:AOLE RS00745
gene id: 436717:AOLE_RS00745
uniprot id: D8JLE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

436717:AOLE RS11160
gene id: 436717:AOLE_RS11160
uniprot id: D8JL73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

436717:AOLE RS11010
gene id: 436717:AOLE_RS11010
uniprot id: D8JL43
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS15660
gene id: 436717:AOLE_RS15660
uniprot id: D8JFC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

436717:AOLE RS03690
gene id: 436717:AOLE_RS03690
uniprot id: D8JDH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

436717:AOLE RS20285
gene id: 436717:AOLE_RS20285
uniprot id: D8JJP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS13205
gene id: 436717:AOLE_RS13205
uniprot id: D8JNH4
names: Subcellular Location Annotation
messages: Cytoplasm

436717:AOLE RS10955
gene id: 436717:AOLE_RS10955
uniprot id: D8JL32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

436717:AOLE RS03520
gene id: 436717:AOLE_RS03520
uniprot id: D8JDE2
names: Similarity
messages: Belongs to the PrpF family.

436717:AOLE RS13315
gene id: 436717:AOLE_RS13315
uniprot id: D8JNJ5
names: Similarity
messages: Belongs to the TmoD/XamoD family.

436717:AOLE RS17135
gene id: 436717:AOLE_RS17135
uniprot id: D8JGX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

436717:AOLE RS16715
gene id: 436717:AOLE_RS16715
uniprot id: D8JGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

436717:AOLE RS08150
gene id: 436717:AOLE_RS08150
uniprot id: D8JIN4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

436717:AOLE RS05035
gene id: 436717:AOLE_RS05035
uniprot id: D8JF14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

436717:AOLE RS06560
gene id: 436717:AOLE_RS06560
uniprot id: D8JGM2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS13675
gene id: 436717:AOLE_RS13675
uniprot id: D8JP48
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS04105
gene id: 436717:AOLE_RS04105
uniprot id: D8JE41
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

436717:AOLE RS01555
gene id: 436717:AOLE_RS01555
uniprot id: D8JM86
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS13980
gene id: 436717:AOLE_RS13980
uniprot id: D8JPB0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

436717:AOLE RS07355
gene id: 436717:AOLE_RS07355
uniprot id: D8JHG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

436717:AOLE RS18340
gene id: 436717:AOLE_RS18340
uniprot id: D8JID1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

436717:AOLE RS03165
gene id: 436717:AOLE_RS03165
uniprot id: D8JNW8
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

436717:AOLE RS18475
gene id: 436717:AOLE_RS18475
uniprot id: D8JIG0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

436717:AOLE RS00840
gene id: 436717:AOLE_RS00840
uniprot id: D8JLG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

436717:AOLE RS17440
gene id: 436717:AOLE_RS17440
uniprot id: D8JH38
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

436717:AOLE RS18870
gene id: 436717:AOLE_RS18870
uniprot id: D8JJ20
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS06775
gene id: 436717:AOLE_RS06775
uniprot id: D8JH49
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

436717:AOLE RS10605
gene id: 436717:AOLE_RS10605
uniprot id: D8JKI1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

436717:AOLE RS01010
gene id: 436717:AOLE_RS01010
uniprot id: D8JLJ7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS09505
gene id: 436717:AOLE_RS09505
uniprot id: D8JJV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

436717:AOLE RS13950
gene id: 436717:AOLE_RS13950
uniprot id: D8JPA4
names: Similarity
messages: Belongs to the VgrG protein family.

436717:AOLE RS11540
gene id: 436717:AOLE_RS11540
uniprot id: D8JLT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS08185
gene id: 436717:AOLE_RS08185
uniprot id: D8JIP1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS10850
gene id: 436717:AOLE_RS10850
uniprot id: D8JL11
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

436717:AOLE RS18440
gene id: 436717:AOLE_RS18440
uniprot id: D8JIF3
names: Similarity
messages: Belongs to the UPF0053 family.

436717:AOLE RS05125
gene id: 436717:AOLE_RS05125
uniprot id: D8JF32
names: Similarity
messages: Belongs to the peptidase S16 family.

436717:AOLE RS00720
gene id: 436717:AOLE_RS00720
uniprot id: D8JLD9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

436717:AOLE RS04045
gene id: 436717:AOLE_RS04045
uniprot id: D8JDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

436717:AOLE RS15985
gene id: 436717:AOLE_RS15985
uniprot id: D8JFJ2
names: Similarity
messages: Belongs to the PhzF family.

436717:AOLE RS13810
gene id: 436717:AOLE_RS13810
uniprot id: D8JP75
names: Similarity
messages: Belongs to the UxaA family.

436717:AOLE RS16865
gene id: 436717:AOLE_RS16865
uniprot id: D8JGS3
names: Subunit
messages: Monomer.

436717:AOLE RS00180
gene id: 436717:AOLE_RS00180
uniprot id: D8JKP4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

436717:AOLE RS09380
gene id: 436717:AOLE_RS09380
uniprot id: D8JJR9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

436717:AOLE RS05905
gene id: 436717:AOLE_RS05905
uniprot id: D8JFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

436717:AOLE RS01855
gene id: 436717:AOLE_RS01855
uniprot id: D8JME8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

436717:AOLE RS00300
gene id: 436717:AOLE_RS00300
uniprot id: D8JKR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

436717:AOLE RS02365
gene id: 436717:AOLE_RS02365
uniprot id: D8JN33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS19230
gene id: 436717:AOLE_RS19230
uniprot id: D8JJ94
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

436717:AOLE RS17615
gene id: 436717:AOLE_RS17615
uniprot id: D8JHK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

436717:AOLE RS04195
gene id: 436717:AOLE_RS04195
uniprot id: D8JE60
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

436717:AOLE RS02855
gene id: 436717:AOLE_RS02855
uniprot id: D8JNQ5
names: Similarity
messages: Belongs to the stealth family.

436717:AOLE RS11915
gene id: 436717:AOLE_RS11915
uniprot id: D8JM08
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS15950
gene id: 436717:AOLE_RS15950
uniprot id: D8JFI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS01965
gene id: 436717:AOLE_RS01965
uniprot id: D8JMH1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS00850
gene id: 436717:AOLE_RS00850
uniprot id: D8JLG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

436717:AOLE RS08195
gene id: 436717:AOLE_RS08195
uniprot id: D8JIP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

436717:AOLE RS16985
gene id: 436717:AOLE_RS16985
uniprot id: D8JGU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

436717:AOLE RS17665
gene id: 436717:AOLE_RS17665
uniprot id: D8JHL7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

436717:AOLE RS11045
gene id: 436717:AOLE_RS11045
uniprot id: D8JL50
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

436717:AOLE RS02700
gene id: 436717:AOLE_RS02700
uniprot id: D8JNM5
names: Similarity
messages: Belongs to the UPF0234 family.

436717:AOLE RS06345
gene id: 436717:AOLE_RS06345
uniprot id: D8JGI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

436717:AOLE RS11740
gene id: 436717:AOLE_RS11740
uniprot id: D8JLX2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS00010
gene id: 436717:AOLE_RS00010
uniprot id: D8JKL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

436717:AOLE RS00310
gene id: 436717:AOLE_RS00310
uniprot id: D8JKS0
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS02010
gene id: 436717:AOLE_RS02010
uniprot id: D8JMI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

436717:AOLE RS00620
gene id: 436717:AOLE_RS00620
uniprot id: D8JKY3
names: Subunit
messages: Homodimer.

436717:AOLE RS07455
gene id: 436717:AOLE_RS07455
uniprot id: D8JHW5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS03120
gene id: 436717:AOLE_RS03120
uniprot id: D8JNV9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

436717:AOLE RS00845
gene id: 436717:AOLE_RS00845
uniprot id: D8JLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

436717:AOLE RS04960
gene id: 436717:AOLE_RS04960
uniprot id: D8JEZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

436717:AOLE RS12730
gene id: 436717:AOLE_RS12730
uniprot id: D8JMV6
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

436717:AOLE RS13825
gene id: 436717:AOLE_RS13825
uniprot id: D8JP78
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

436717:AOLE RS14610
gene id: 436717:AOLE_RS14610
uniprot id: D8JDZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

436717:AOLE RS14290
gene id: 436717:AOLE_RS14290
uniprot id: D8JDT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS03925
gene id: 436717:AOLE_RS03925
uniprot id: D8JDM1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS09900
gene id: 436717:AOLE_RS09900
uniprot id: D8JK37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

436717:AOLE RS02240
gene id: 436717:AOLE_RS02240
uniprot id: D8JN11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

436717:AOLE RS19080
gene id: 436717:AOLE_RS19080
uniprot id: D8JJ64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell inner membrane

436717:AOLE RS19115
gene id: 436717:AOLE_RS19115
uniprot id: D8JJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

436717:AOLE RS09160
gene id: 436717:AOLE_RS09160
uniprot id: D8JJM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS02565
gene id: 436717:AOLE_RS02565
uniprot id: D8JN68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

436717:AOLE RS17805
gene id: 436717:AOLE_RS17805
uniprot id: D8JHP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

436717:AOLE RS09835
gene id: 436717:AOLE_RS09835
uniprot id: D8JK23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS03145
gene id: 436717:AOLE_RS03145
uniprot id: D8JNW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

436717:AOLE RS17325
gene id: 436717:AOLE_RS17325
uniprot id: D8JH15
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS06765
gene id: 436717:AOLE_RS06765
uniprot id: D8JH47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

436717:AOLE RS02930
gene id: 436717:AOLE_RS02930
uniprot id: D8JNS0
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS00645
gene id: 436717:AOLE_RS00645
uniprot id: D8JKY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

436717:AOLE RS06545
gene id: 436717:AOLE_RS06545
uniprot id: D8JGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

436717:AOLE RS07500
gene id: 436717:AOLE_RS07500
uniprot id: D8JHX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

436717:AOLE RS05020
gene id: 436717:AOLE_RS05020
uniprot id: D8JF11
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

436717:AOLE RS13400
gene id: 436717:AOLE_RS13400
uniprot id: D8JNL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS15420
gene id: 436717:AOLE_RS15420
uniprot id: D8JEU4
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

436717:AOLE RS07495
gene id: 436717:AOLE_RS07495
uniprot id: D8JHX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

436717:AOLE RS11635
gene id: 436717:AOLE_RS11635
uniprot id: D8JLV1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS16735
gene id: 436717:AOLE_RS16735
uniprot id: D8JGB1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS06455
gene id: 436717:AOLE_RS06455
uniprot id: D8JGK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

436717:AOLE RS03760
gene id: 436717:AOLE_RS03760
uniprot id: D8JDJ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

436717:AOLE RS15370
gene id: 436717:AOLE_RS15370
uniprot id: D8JET5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

436717:AOLE RS02095
gene id: 436717:AOLE_RS02095
uniprot id: D8JMY2
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS18635
gene id: 436717:AOLE_RS18635
uniprot id: D8JII8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

436717:AOLE RS18760
gene id: 436717:AOLE_RS18760
uniprot id: D8JIL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS12555
gene id: 436717:AOLE_RS12555
uniprot id: D8JMS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

436717:AOLE RS19095
gene id: 436717:AOLE_RS19095
uniprot id: D8JJ67
names: Similarity
messages: Belongs to the phosphohexose mutase family.

436717:AOLE RS00965
gene id: 436717:AOLE_RS00965
uniprot id: D8JLI8
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

436717:AOLE RS05435
gene id: 436717:AOLE_RS05435
uniprot id: D8JFM8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

436717:AOLE RS05840
gene id: 436717:AOLE_RS05840
uniprot id: D8JFV6
names: Similarity
messages: Belongs to the UPF0246 family.

436717:AOLE RS12600
gene id: 436717:AOLE_RS12600
uniprot id: D8JMT0
names: Similarity
messages: Belongs to the OprB family.

436717:AOLE RS09720
gene id: 436717:AOLE_RS09720
uniprot id: D8JJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS11450
gene id: 436717:AOLE_RS11450
uniprot id: D8JLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS17750
gene id: 436717:AOLE_RS17750
uniprot id: D8JHN4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS14425
gene id: 436717:AOLE_RS14425
uniprot id: D8JDW0
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS19190
gene id: 436717:AOLE_RS19190
uniprot id: D8JJ86
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

436717:AOLE RS01350
gene id: 436717:AOLE_RS01350
uniprot id: D8JM49
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS15475
gene id: 436717:AOLE_RS15475
uniprot id: D8JF90
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

436717:AOLE RS18450
gene id: 436717:AOLE_RS18450
uniprot id: D8JIF5
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS08715
gene id: 436717:AOLE_RS08715
uniprot id: D8JIZ7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

436717:AOLE RS02900
gene id: 436717:AOLE_RS02900
uniprot id: D8JNR4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS11290
gene id: 436717:AOLE_RS11290
uniprot id: D8JL97
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

436717:AOLE RS05940
gene id: 436717:AOLE_RS05940
uniprot id: D8JFX6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

436717:AOLE RS18865
gene id: 436717:AOLE_RS18865
uniprot id: D3JTG2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

436717:AOLE RS17935
gene id: 436717:AOLE_RS17935
uniprot id: D8JHR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS17070
gene id: 436717:AOLE_RS17070
uniprot id: D8JGW4
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

436717:AOLE RS19175
gene id: 436717:AOLE_RS19175
uniprot id: D8JJ83
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

436717:AOLE RS10170
gene id: 436717:AOLE_RS10170
uniprot id: D8JK93
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS06835
gene id: 436717:AOLE_RS06835
uniprot id: D8JH61
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

436717:AOLE RS02800
gene id: 436717:AOLE_RS02800
uniprot id: D8JNP4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

436717:AOLE RS15685
gene id: 436717:AOLE_RS15685
uniprot id: D8JFD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS07310
gene id: 436717:AOLE_RS07310
uniprot id: D8JHF9
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

436717:AOLE RS18375
gene id: 436717:AOLE_RS18375
uniprot id: D8JID9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS12910
gene id: 436717:AOLE_RS12910
uniprot id: D8JNB5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

436717:AOLE RS15350
gene id: 436717:AOLE_RS15350
uniprot id: D8JET1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

436717:AOLE RS04700
gene id: 436717:AOLE_RS04700
uniprot id: D8JEG3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

436717:AOLE RS16555
gene id: 436717:AOLE_RS16555
uniprot id: D8JG75
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

436717:AOLE RS18220
gene id: 436717:AOLE_RS18220
uniprot id: D8JIA8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

436717:AOLE RS06640
gene id: 436717:AOLE_RS06640
uniprot id: D8JGN8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS04270
gene id: 436717:AOLE_RS04270
uniprot id: D8JE76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

436717:AOLE RS18145
gene id: 436717:AOLE_RS18145
uniprot id: D8JHV6
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

436717:AOLE RS10880
gene id: 436717:AOLE_RS10880
uniprot id: D8JL17
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

436717:AOLE RS13760
gene id: 436717:AOLE_RS13760
uniprot id: D8JP65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS02155
gene id: 436717:AOLE_RS02155
uniprot id: D8JMZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

436717:AOLE RS00790
gene id: 436717:AOLE_RS00790
uniprot id: D8JLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS18915
gene id: 436717:AOLE_RS18915
uniprot id: D8JJ29
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

436717:AOLE RS15450
gene id: 436717:AOLE_RS15450
uniprot id: D8JEU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

436717:AOLE RS05640
gene id: 436717:AOLE_RS05640
uniprot id: D8JFR7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

436717:AOLE RS08450
gene id: 436717:AOLE_RS08450
uniprot id: D8JIU4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS00445
gene id: 436717:AOLE_RS00445
uniprot id: D8JKU8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

436717:AOLE RS17205
gene id: 436717:AOLE_RS17205
uniprot id: D8JGZ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

436717:AOLE RS17170
gene id: 436717:AOLE_RS17170
uniprot id: D8JGY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

436717:AOLE RS09465
gene id: 436717:AOLE_RS09465
uniprot id: D8JJU6
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS15190
gene id: 436717:AOLE_RS15190
uniprot id: D8JEP8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS01905
gene id: 436717:AOLE_RS01905
uniprot id: D8JMF8
names: Similarity
messages: Belongs to the YciI family.

436717:AOLE RS10855
gene id: 436717:AOLE_RS10855
uniprot id: D8JL12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS16935
gene id: 436717:AOLE_RS16935
uniprot id: D8JGT7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS11705
gene id: 436717:AOLE_RS11705
uniprot id: D8JLW5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

436717:AOLE RS05645
gene id: 436717:AOLE_RS05645
uniprot id: D8JFR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS10725
gene id: 436717:AOLE_RS10725
uniprot id: D8JKK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS00280
gene id: 436717:AOLE_RS00280
uniprot id: D8JKR4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS18420
gene id: 436717:AOLE_RS18420
uniprot id: D8JIE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

436717:AOLE RS16845
gene id: 436717:AOLE_RS16845
uniprot id: D8JGR9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

436717:AOLE RS00275
gene id: 436717:AOLE_RS00275
uniprot id: D8JKR3
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

436717:AOLE RS03030
gene id: 436717:AOLE_RS03030
uniprot id: D8JNU0
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS15315
gene id: 436717:AOLE_RS15315
uniprot id: D8JES4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

436717:AOLE RS00705
gene id: 436717:AOLE_RS00705
uniprot id: D8JLD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

436717:AOLE RS04070
gene id: 436717:AOLE_RS04070
uniprot id: D8JE34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS06435
gene id: 436717:AOLE_RS06435
uniprot id: D8JGJ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

436717:AOLE RS01695
gene id: 436717:AOLE_RS01695
uniprot id: D8JMB5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

436717:AOLE RS14260
gene id: 436717:AOLE_RS14260
uniprot id: D8JDS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

436717:AOLE RS08620
gene id: 436717:AOLE_RS08620
uniprot id: D8JIX8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS12190
gene id: 436717:AOLE_RS12190
uniprot id: D8JMJ5
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS06585
gene id: 436717:AOLE_RS06585
uniprot id: D8JGM7
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

436717:AOLE RS00805
gene id: 436717:AOLE_RS00805
uniprot id: D8JLF6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

436717:AOLE RS17400
gene id: 436717:AOLE_RS17400
uniprot id: D8JH30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

436717:AOLE RS04500
gene id: 436717:AOLE_RS04500
uniprot id: D8JEC2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

436717:AOLE RS00455
gene id: 436717:AOLE_RS00455
uniprot id: D8JKV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

436717:AOLE RS08125
gene id: 436717:AOLE_RS08125
uniprot id: D8JIM9
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS01620
gene id: 436717:AOLE_RS01620
uniprot id: D8JM99
names: Similarity
messages: Belongs to the RutC family.

436717:AOLE RS03450
gene id: 436717:AOLE_RS03450
uniprot id: D8JDD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

436717:AOLE RS01200
gene id: 436717:AOLE_RS01200
uniprot id: D8JLN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

436717:AOLE RS08455
gene id: 436717:AOLE_RS08455
uniprot id: D8JIU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

436717:AOLE RS14175
gene id: 436717:AOLE_RS14175
uniprot id: D8JDQ8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

436717:AOLE RS14535
gene id: 436717:AOLE_RS14535
uniprot id: D8JDY2
names: Similarity
messages: Belongs to the TPP enzyme family.

436717:AOLE RS16250
gene id: 436717:AOLE_RS16250
uniprot id: D8JG19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

436717:AOLE RS15635
gene id: 436717:AOLE_RS15635
uniprot id: D8JFC0
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

436717:AOLE RS13420
gene id: 436717:AOLE_RS13420
uniprot id: D8JNL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

436717:AOLE RS11620
gene id: 436717:AOLE_RS11620
uniprot id: D8JLU8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS16160
gene id: 436717:AOLE_RS16160
uniprot id: D8JG05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

436717:AOLE RS02430
gene id: 436717:AOLE_RS02430
uniprot id: D8JN46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

436717:AOLE RS04330
gene id: 436717:AOLE_RS04330
uniprot id: D8JE88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

436717:AOLE RS15280
gene id: 436717:AOLE_RS15280
uniprot id: D8JER7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

436717:AOLE RS14540
gene id: 436717:AOLE_RS14540
uniprot id: D8JDY3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

436717:AOLE RS04635
gene id: 436717:AOLE_RS04635
uniprot id: D8JEF0
names: Subunit
messages: Homodimer.

436717:AOLE RS01465
gene id: 436717:AOLE_RS01465
uniprot id: D8JM68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

436717:AOLE RS11125
gene id: 436717:AOLE_RS11125
uniprot id: D8JL66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

436717:AOLE RS06515
gene id: 436717:AOLE_RS06515
uniprot id: D8JGL3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

436717:AOLE RS06655
gene id: 436717:AOLE_RS06655
uniprot id: D8JGP1
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

436717:AOLE RS01375
gene id: 436717:AOLE_RS01375
uniprot id: D8JM54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

436717:AOLE RS16415
gene id: 436717:AOLE_RS16415
uniprot id: D8JG47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

436717:AOLE RS07220
gene id: 436717:AOLE_RS07220
uniprot id: D8JHE0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

436717:AOLE RS03180
gene id: 436717:AOLE_RS03180
uniprot id: D8JNX1
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS16530
gene id: 436717:AOLE_RS16530
uniprot id: D8JG70
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS17940
gene id: 436717:AOLE_RS17940
uniprot id: D8JHS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

436717:AOLE RS13430
gene id: 436717:AOLE_RS13430
uniprot id: D8JNL8
names: Similarity
messages: Belongs to the GST superfamily.

436717:AOLE RS17515
gene id: 436717:AOLE_RS17515
uniprot id: D8JHI7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

436717:AOLE RS00210
gene id: 436717:AOLE_RS00210
uniprot id: D8JKQ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS08730
gene id: 436717:AOLE_RS08730
uniprot id: D8JJ00
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

436717:AOLE RS18580
gene id: 436717:AOLE_RS18580
uniprot id: D8JIH7
names: Similarity
messages: Belongs to the DprA/Smf family.

436717:AOLE RS02300
gene id: 436717:AOLE_RS02300
uniprot id: D8JN24
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

436717:AOLE RS17075
gene id: 436717:AOLE_RS17075
uniprot id: D8JGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS08725
gene id: 436717:AOLE_RS08725
uniprot id: D8JIZ9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

436717:AOLE RS10860
gene id: 436717:AOLE_RS10860
uniprot id: D8JL13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS07360
gene id: 436717:AOLE_RS07360
uniprot id: D8JHG9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

436717:AOLE RS04415
gene id: 436717:AOLE_RS04415
uniprot id: D8JEA5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

436717:AOLE RS01295
gene id: 436717:AOLE_RS01295
uniprot id: D8JLQ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

436717:AOLE RS11460
gene id: 436717:AOLE_RS11460
uniprot id: D8JLR4
names: Similarity
messages: Belongs to the ArsC family.

436717:AOLE RS14020
gene id: 436717:AOLE_RS14020
uniprot id: D8JPB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

436717:AOLE RS14385
gene id: 436717:AOLE_RS14385
uniprot id: D8JDV2
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS14685
gene id: 436717:AOLE_RS14685
uniprot id: D8JE12
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS06130
gene id: 436717:AOLE_RS06130
uniprot id: D8JGD7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS00880
gene id: 436717:AOLE_RS00880
uniprot id: D8JLH1
names: Similarity
messages: Belongs to the SsuE family.

436717:AOLE RS07420
gene id: 436717:AOLE_RS07420
uniprot id: D8JHI1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

436717:AOLE RS05395
gene id: 436717:AOLE_RS05395
uniprot id: D8JFM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

436717:AOLE RS10405
gene id: 436717:AOLE_RS10405
uniprot id: D8JKE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

436717:AOLE RS14265
gene id: 436717:AOLE_RS14265
uniprot id: D8JDS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

436717:AOLE RS01690
gene id: 436717:AOLE_RS01690
uniprot id: D8JMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

436717:AOLE RS07480
gene id: 436717:AOLE_RS07480
uniprot id: D8JHX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

436717:AOLE RS11720
gene id: 436717:AOLE_RS11720
uniprot id: D8JLW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

436717:AOLE RS03130
gene id: 436717:AOLE_RS03130
uniprot id: D8JNW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

436717:AOLE RS08225
gene id: 436717:AOLE_RS08225
uniprot id: D8JIP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

436717:AOLE RS05085
gene id: 436717:AOLE_RS05085
uniprot id: D8JF24
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

436717:AOLE RS06160
gene id: 436717:AOLE_RS06160
uniprot id: D8JGE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

436717:AOLE RS03995
gene id: 436717:AOLE_RS03995
uniprot id: D8JDN2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS10845
gene id: 436717:AOLE_RS10845
uniprot id: D8JL10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

436717:AOLE RS05095
gene id: 436717:AOLE_RS05095
uniprot id: D8JF26
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

436717:AOLE RS19015
gene id: 436717:AOLE_RS19015
uniprot id: D8JJ50
names: Similarity
messages: Belongs to the VgrG protein family.

436717:AOLE RS06730
gene id: 436717:AOLE_RS06730
uniprot id: D8JGQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

436717:AOLE RS15480
gene id: 436717:AOLE_RS15480
uniprot id: D8JF91
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

436717:AOLE RS08240
gene id: 436717:AOLE_RS08240
uniprot id: D8JIQ2
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

436717:AOLE RS08865
gene id: 436717:AOLE_RS08865
uniprot id: D8JJG0
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS18255
gene id: 436717:AOLE_RS18255
uniprot id: D8JIB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

436717:AOLE RS03930
gene id: 436717:AOLE_RS03930
uniprot id: D8JDM2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

436717:AOLE RS18095
gene id: 436717:AOLE_RS18095
uniprot id: D8JHU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

436717:AOLE RS18165
gene id: 436717:AOLE_RS18165
uniprot id: D8JHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

436717:AOLE RS00325
gene id: 436717:AOLE_RS00325
uniprot id: D8JKS3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

436717:AOLE RS03425
gene id: 436717:AOLE_RS03425
uniprot id: D8JDC4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

436717:AOLE RS05525
gene id: 436717:AOLE_RS05525
uniprot id: D8JFP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

436717:AOLE RS03655
gene id: 436717:AOLE_RS03655
uniprot id: D8JDG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

436717:AOLE RS03815
gene id: 436717:AOLE_RS03815
uniprot id: D8JDK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS07805
gene id: 436717:AOLE_RS07805
uniprot id: D8JI35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS18640
gene id: 436717:AOLE_RS18640
uniprot id: D8JII9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

436717:AOLE RS02245
gene id: 436717:AOLE_RS02245
uniprot id: D8JN12
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

436717:AOLE RS01635
gene id: 436717:AOLE_RS01635
uniprot id: D8JMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

436717:AOLE RS01300
gene id: 436717:AOLE_RS01300
uniprot id: D8JLQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

436717:AOLE RS11135
gene id: 436717:AOLE_RS11135
uniprot id: D8JL68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

436717:AOLE RS01030
gene id: 436717:AOLE_RS01030
uniprot id: D8JLK1
names: Similarity
messages: Belongs to the pirin family.

436717:AOLE RS04880
gene id: 436717:AOLE_RS04880
uniprot id: D8JEY2
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

436717:AOLE RS11315
gene id: 436717:AOLE_RS11315
uniprot id: D8JLA2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

436717:AOLE RS02125
gene id: 436717:AOLE_RS02125
uniprot id: D8JMY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

436717:AOLE RS13000
gene id: 436717:AOLE_RS13000
uniprot id: D8JND3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

436717:AOLE RS05120
gene id: 436717:AOLE_RS05120
uniprot id: D8JF31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS11715
gene id: 436717:AOLE_RS11715
uniprot id: D8JLW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS07205
gene id: 436717:AOLE_RS07205
uniprot id: D8JHD7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

436717:AOLE RS15220
gene id: 436717:AOLE_RS15220
uniprot id: D8JEQ4
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

436717:AOLE RS03710
gene id: 436717:AOLE_RS03710
uniprot id: D8JDH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

436717:AOLE RS11555
gene id: 436717:AOLE_RS11555
uniprot id: D8JLT5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS04885
gene id: 436717:AOLE_RS04885
uniprot id: D8JEY3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

436717:AOLE RS04820
gene id: 436717:AOLE_RS04820
uniprot id: D8JEX0
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS03640
gene id: 436717:AOLE_RS03640
uniprot id: D8JDG5
names: Similarity
messages: Belongs to the UPF0145 family.

436717:AOLE RS10540
gene id: 436717:AOLE_RS10540
uniprot id: D8JKG8
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

436717:AOLE RS05305
gene id: 436717:AOLE_RS05305
uniprot id: D8JF70
names: Similarity
messages: Belongs to the YkuD family.

436717:AOLE RS08515
gene id: 436717:AOLE_RS08515
uniprot id: D8JIV7
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

436717:AOLE RS18350
gene id: 436717:AOLE_RS18350
uniprot id: D8JID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS12515
gene id: 436717:AOLE_RS12515
uniprot id: D8JMR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

436717:AOLE RS04305
gene id: 436717:AOLE_RS04305
uniprot id: D8JE83
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

436717:AOLE RS01860
gene id: 436717:AOLE_RS01860
uniprot id: D8JME9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

436717:AOLE RS16450
gene id: 436717:AOLE_RS16450
uniprot id: D8JG54
names: Similarity
messages: Belongs to the GppA/Ppx family.

436717:AOLE RS04360
gene id: 436717:AOLE_RS04360
uniprot id: D8JE94
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

436717:AOLE RS04490
gene id: 436717:AOLE_RS04490
uniprot id: D8JEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

436717:AOLE RS13580
gene id: 436717:AOLE_RS13580
uniprot id: D8JP27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

436717:AOLE RS00265
gene id: 436717:AOLE_RS00265
uniprot id: D8JKR1
names: Similarity
messages: Belongs to the UPF0260 family.

436717:AOLE RS04235
gene id: 436717:AOLE_RS04235
uniprot id: D8JE68
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS01850
gene id: 436717:AOLE_RS01850
uniprot id: D8JME7
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

436717:AOLE RS09975
gene id: 436717:AOLE_RS09975
uniprot id: D8JK53
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS16670
gene id: 436717:AOLE_RS16670
uniprot id: D8JG98
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

436717:AOLE RS18205
gene id: 436717:AOLE_RS18205
uniprot id: D8JIA5
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

436717:AOLE RS05690
gene id: 436717:AOLE_RS05690
uniprot id: D8JFS7
names: Similarity
messages: Belongs to the PhzF family.

436717:AOLE RS12545
gene id: 436717:AOLE_RS12545
uniprot id: D8JMR8
names: Similarity
messages: Belongs to the UPF0276 family.

436717:AOLE RS17150
gene id: 436717:AOLE_RS17150
uniprot id: D8JGY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS17520
gene id: 436717:AOLE_RS17520
uniprot id: D8JHI8
names: Similarity
messages: Belongs to the Gfa family.

436717:AOLE RS14095
gene id: 436717:AOLE_RS14095
uniprot id: D8JPD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

436717:AOLE RS09615
gene id: 436717:AOLE_RS09615
uniprot id: D8JJX8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

436717:AOLE RS08590
gene id: 436717:AOLE_RS08590
uniprot id: D8JIX2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS11300
gene id: 436717:AOLE_RS11300
uniprot id: D8JL99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

436717:AOLE RS02395
gene id: 436717:AOLE_RS02395
uniprot id: D8JN39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

436717:AOLE RS06580
gene id: 436717:AOLE_RS06580
uniprot id: D8JGM6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

436717:AOLE RS11130
gene id: 436717:AOLE_RS11130
uniprot id: D8JL67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

436717:AOLE RS01605
gene id: 436717:AOLE_RS01605
uniprot id: D8JM96
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS12960
gene id: 436717:AOLE_RS12960
uniprot id: D8JNC5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

436717:AOLE RS09605
gene id: 436717:AOLE_RS09605
uniprot id: D8JJX6
names: Similarity
messages: Belongs to the sulfatase family.

436717:AOLE RS03800
gene id: 436717:AOLE_RS03800
uniprot id: D8JDJ8
names: Similarity
messages: Belongs to the citrate synthase family.

436717:AOLE RS05880
gene id: 436717:AOLE_RS05880
uniprot id: D8JFW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

436717:AOLE RS05460
gene id: 436717:AOLE_RS05460
uniprot id: D8JFN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

436717:AOLE RS11665
gene id: 436717:AOLE_RS11665
uniprot id: D8JLV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS00290
gene id: 436717:AOLE_RS00290
uniprot id: D8JKR6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

436717:AOLE RS09700
gene id: 436717:AOLE_RS09700
uniprot id: D8JJZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

436717:AOLE RS09715
gene id: 436717:AOLE_RS09715
uniprot id: D8JJZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS11400
gene id: 436717:AOLE_RS11400
uniprot id: D8JLC0
names: Similarity
messages: Belongs to the asparaginase 1 family.

436717:AOLE RS11550
gene id: 436717:AOLE_RS11550
uniprot id: D8JLT4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS16325
gene id: 436717:AOLE_RS16325
uniprot id: D8JG34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS02200
gene id: 436717:AOLE_RS02200
uniprot id: D8JN03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

436717:AOLE RS15520
gene id: 436717:AOLE_RS15520
uniprot id: D8JF97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

436717:AOLE RS12950
gene id: 436717:AOLE_RS12950
uniprot id: D8JNC3
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS09545
gene id: 436717:AOLE_RS09545
uniprot id: D8JJW4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS10785
gene id: 436717:AOLE_RS10785
uniprot id: D8JKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

436717:AOLE RS04675
gene id: 436717:AOLE_RS04675
uniprot id: D8JEF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

436717:AOLE RS16470
gene id: 436717:AOLE_RS16470
uniprot id: D8JG58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

436717:AOLE RS16520
gene id: 436717:AOLE_RS16520
uniprot id: D8JG68
names: Similarity
messages: Belongs to the GST superfamily.

436717:AOLE RS16330
gene id: 436717:AOLE_RS16330
uniprot id: D8JG35
names: Similarity
messages: Belongs to the BolA/IbaG family.

436717:AOLE RS14380
gene id: 436717:AOLE_RS14380
uniprot id: D8JDV1
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS18225
gene id: 436717:AOLE_RS18225
uniprot id: D8JIA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

436717:AOLE RS00775
gene id: 436717:AOLE_RS00775
uniprot id: D8JLF0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

436717:AOLE RS04365
gene id: 436717:AOLE_RS04365
uniprot id: D8JE95
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS15730
gene id: 436717:AOLE_RS15730
uniprot id: D8JFD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS12875
gene id: 436717:AOLE_RS12875
uniprot id: D8JNA8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS15620
gene id: 436717:AOLE_RS15620
uniprot id: D8JFB7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS01835
gene id: 436717:AOLE_RS01835
uniprot id: D8JME4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

436717:AOLE RS03160
gene id: 436717:AOLE_RS03160
uniprot id: D8JNW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

436717:AOLE RS01355
gene id: 436717:AOLE_RS01355
uniprot id: D8JM50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Membrane

436717:AOLE RS19200
gene id: 436717:AOLE_RS19200
uniprot id: D8JJ88
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

436717:AOLE RS18060
gene id: 436717:AOLE_RS18060
uniprot id: D8JHU4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS11440
gene id: 436717:AOLE_RS11440
uniprot id: D8JLC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

436717:AOLE RS05265
gene id: 436717:AOLE_RS05265
uniprot id: D8JF61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

436717:AOLE RS03645
gene id: 436717:AOLE_RS03645
uniprot id: D8JDG6
names: Similarity
messages: Belongs to the UPF0145 family.

436717:AOLE RS05960
gene id: 436717:AOLE_RS05960
uniprot id: D8JFY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

436717:AOLE RS01995
gene id: 436717:AOLE_RS01995
uniprot id: D8JMH7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

436717:AOLE RS08400
gene id: 436717:AOLE_RS08400
uniprot id: D8JIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

436717:AOLE RS10630
gene id: 436717:AOLE_RS10630
uniprot id: D8JKI6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

436717:AOLE RS08350
gene id: 436717:AOLE_RS08350
uniprot id: D8JIS3
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS03370
gene id: 436717:AOLE_RS03370
uniprot id: D8JP03
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

436717:AOLE RS00955
gene id: 436717:AOLE_RS00955
uniprot id: D8JLI6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS19060
gene id: 436717:AOLE_RS19060
uniprot id: D8JJ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

436717:AOLE RS08420
gene id: 436717:AOLE_RS08420
uniprot id: D8JIT7
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

436717:AOLE RS04510
gene id: 436717:AOLE_RS04510
uniprot id: D8JEC4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

436717:AOLE RS15825
gene id: 436717:AOLE_RS15825
uniprot id: D8JFG0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

436717:AOLE RS18695
gene id: 436717:AOLE_RS18695
uniprot id: D8JIK1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

436717:AOLE RS01410
gene id: 436717:AOLE_RS01410
uniprot id: D8JM61
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS16425
gene id: 436717:AOLE_RS16425
uniprot id: D8JG49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

436717:AOLE RS08840
gene id: 436717:AOLE_RS08840
uniprot id: D8JJF4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS20755
gene id: 436717:AOLE_RS20755
uniprot id: D8JMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS14240
gene id: 436717:AOLE_RS14240
uniprot id: D8JDS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

436717:AOLE RS07045
gene id: 436717:AOLE_RS07045
uniprot id: D8JHA4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS00755
gene id: 436717:AOLE_RS00755
uniprot id: D8JLE6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

436717:AOLE RS16775
gene id: 436717:AOLE_RS16775
uniprot id: D8JGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

436717:AOLE RS17005
gene id: 436717:AOLE_RS17005
uniprot id: D8JGV1
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

436717:AOLE RS16590
gene id: 436717:AOLE_RS16590
uniprot id: D8JG82
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

436717:AOLE RS02030
gene id: 436717:AOLE_RS02030
uniprot id: D8JMX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

436717:AOLE RS12175
gene id: 436717:AOLE_RS12175
uniprot id: D8JMJ2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS14660
gene id: 436717:AOLE_RS14660
uniprot id: D8JE07
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS05365
gene id: 436717:AOLE_RS05365
uniprot id: D8JF82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS13280
gene id: 436717:AOLE_RS13280
uniprot id: D8JNI8
names: Similarity
messages: Belongs to the Gfa family.

436717:AOLE RS17095
gene id: 436717:AOLE_RS17095
uniprot id: D8JGW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

436717:AOLE RS04055
gene id: 436717:AOLE_RS04055
uniprot id: D8JDP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

436717:AOLE RS17810
gene id: 436717:AOLE_RS17810
uniprot id: D8JHP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

436717:AOLE RS05765
gene id: 436717:AOLE_RS05765
uniprot id: D8JFU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

436717:AOLE RS17760
gene id: 436717:AOLE_RS17760
uniprot id: D8JHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS15570
gene id: 436717:AOLE_RS15570
uniprot id: D8JFA7
names: Similarity
messages: Belongs to the fabD family.

436717:AOLE RS18210
gene id: 436717:AOLE_RS18210
uniprot id: D8JIA6
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

436717:AOLE RS06310
gene id: 436717:AOLE_RS06310
uniprot id: D8JGH3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS15515
gene id: 436717:AOLE_RS15515
uniprot id: D8JF96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

436717:AOLE RS15230
gene id: 436717:AOLE_RS15230
uniprot id: D8JEQ6
names: Similarity
messages: Belongs to the hemerythrin family.

436717:AOLE RS16445
gene id: 436717:AOLE_RS16445
uniprot id: D8JG53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

436717:AOLE RS19150
gene id: 436717:AOLE_RS19150
uniprot id: D8JJ78
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

436717:AOLE RS01685
gene id: 436717:AOLE_RS01685
uniprot id: D8JMB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

436717:AOLE RS01640
gene id: 436717:AOLE_RS01640
uniprot id: D8JMA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

436717:AOLE RS10070
gene id: 436717:AOLE_RS10070
uniprot id: D8JK72
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS02685
gene id: 436717:AOLE_RS02685
uniprot id: D8JN87
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

436717:AOLE RS07460
gene id: 436717:AOLE_RS07460
uniprot id: D8JHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

436717:AOLE RS10280
gene id: 436717:AOLE_RS10280
uniprot id: D8JKB5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

436717:AOLE RS05510
gene id: 436717:AOLE_RS05510
uniprot id: D8JFP3
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS08120
gene id: 436717:AOLE_RS08120
uniprot id: D8JIM8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS10290
gene id: 436717:AOLE_RS10290
uniprot id: D8JKB7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

436717:AOLE RS07055
gene id: 436717:AOLE_RS07055
uniprot id: D8JHA6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

436717:AOLE RS18645
gene id: 436717:AOLE_RS18645
uniprot id: D8JIJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

436717:AOLE RS03705
gene id: 436717:AOLE_RS03705
uniprot id: D8JDH8
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

436717:AOLE RS11215
gene id: 436717:AOLE_RS11215
uniprot id: D8JL83
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS08405
gene id: 436717:AOLE_RS08405
uniprot id: D8JIT4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

436717:AOLE RS14680
gene id: 436717:AOLE_RS14680
uniprot id: D8JE11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS02235
gene id: 436717:AOLE_RS02235
uniprot id: D8JN10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

436717:AOLE RS17775
gene id: 436717:AOLE_RS17775
uniprot id: D8JHN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

436717:AOLE RS00155
gene id: 436717:AOLE_RS00155
uniprot id: D8JKN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

436717:AOLE RS03105
gene id: 436717:AOLE_RS03105
uniprot id: D8JNV5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

436717:AOLE RS14565
gene id: 436717:AOLE_RS14565
uniprot id: D8JDY8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS16560
gene id: 436717:AOLE_RS16560
uniprot id: D8JG76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

436717:AOLE RS19465
gene id: 436717:AOLE_RS19465
uniprot id: D8JJD7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

436717:AOLE RS09205
gene id: 436717:AOLE_RS09205
uniprot id: D8JJN2
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS12765
gene id: 436717:AOLE_RS12765
uniprot id: D8JMW3
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

436717:AOLE RS14210
gene id: 436717:AOLE_RS14210
uniprot id: D8JDR6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

436717:AOLE RS10490
gene id: 436717:AOLE_RS10490
uniprot id: D8JKF8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

436717:AOLE RS09645
gene id: 436717:AOLE_RS09645
uniprot id: D8JJY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

436717:AOLE RS00635
gene id: 436717:AOLE_RS00635
uniprot id: D8JKY6
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

436717:AOLE RS00515
gene id: 436717:AOLE_RS00515
uniprot id: D8JKW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

436717:AOLE RS05790
gene id: 436717:AOLE_RS05790
uniprot id: D8JFU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

436717:AOLE RS18880
gene id: 436717:AOLE_RS18880
uniprot id: D8JJ22
names: Similarity
messages: Belongs to the HIBADH-related family.

436717:AOLE RS00125
gene id: 436717:AOLE_RS00125
uniprot id: D8JKN3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

436717:AOLE RS02765
gene id: 436717:AOLE_RS02765
uniprot id: D8JNN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

436717:AOLE RS13605
gene id: 436717:AOLE_RS13605
uniprot id: D8JP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

436717:AOLE RS01990
gene id: 436717:AOLE_RS01990
uniprot id: D8JMH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

436717:AOLE RS07020
gene id: 436717:AOLE_RS07020
uniprot id: D8JH99
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS05670
gene id: 436717:AOLE_RS05670
uniprot id: D8JFS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS15665
gene id: 436717:AOLE_RS15665
uniprot id: D8JFC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

436717:AOLE RS08505
gene id: 436717:AOLE_RS08505
uniprot id: D8JIV5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

436717:AOLE RS11055
gene id: 436717:AOLE_RS11055
uniprot id: D8JL52
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

436717:AOLE RS05025
gene id: 436717:AOLE_RS05025
uniprot id: D8JF12
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS11590
gene id: 436717:AOLE_RS11590
uniprot id: D8JLU2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

436717:AOLE RS18460
gene id: 436717:AOLE_RS18460
uniprot id: D8JIF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

436717:AOLE RS03415
gene id: 436717:AOLE_RS03415
uniprot id: D8JDC2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

436717:AOLE RS18300
gene id: 436717:AOLE_RS18300
uniprot id: D8JIC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

436717:AOLE RS17900
gene id: 436717:AOLE_RS17900
uniprot id: D8JHR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

436717:AOLE RS09950
gene id: 436717:AOLE_RS09950
uniprot id: D8JK48
names: Similarity
messages: Belongs to the isochorismate synthase family.

436717:AOLE RS06890
gene id: 436717:AOLE_RS06890
uniprot id: D8JH72
names: Function
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate.

436717:AOLE RS18120
gene id: 436717:AOLE_RS18120
uniprot id: D8JHV1
names: Similarity
messages: Belongs to the GSP N family.

436717:AOLE RS12735
gene id: 436717:AOLE_RS12735
uniprot id: D8JMV7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

436717:AOLE RS01485
gene id: 436717:AOLE_RS01485
uniprot id: D8JM72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

436717:AOLE RS16630
gene id: 436717:AOLE_RS16630
uniprot id: D8JG90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

436717:AOLE RS05650
gene id: 436717:AOLE_RS05650
uniprot id: D8JFR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

436717:AOLE RS03850
gene id: 436717:AOLE_RS03850
uniprot id: D8JDK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

436717:AOLE RS11500
gene id: 436717:AOLE_RS11500
uniprot id: D8JLS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS14360
gene id: 436717:AOLE_RS14360
uniprot id: D8JDU7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS02805
gene id: 436717:AOLE_RS02805
uniprot id: D8JNP5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS01015
gene id: 436717:AOLE_RS01015
uniprot id: D8JLJ8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

436717:AOLE RS14460
gene id: 436717:AOLE_RS14460
uniprot id: D8JDW7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

436717:AOLE RS14135
gene id: 436717:AOLE_RS14135
uniprot id: D8JDP9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

436717:AOLE RS17725
gene id: 436717:AOLE_RS17725
uniprot id: D8JHM9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

436717:AOLE RS12145
gene id: 436717:AOLE_RS12145
uniprot id: D8JMI6
names: Similarity
messages: Belongs to the DapA family.

436717:AOLE RS15640
gene id: 436717:AOLE_RS15640
uniprot id: D8JFC1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

436717:AOLE RS00915
gene id: 436717:AOLE_RS00915
uniprot id: D8JLH8
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS18930
gene id: 436717:AOLE_RS18930
uniprot id: D8JJ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS15615
gene id: 436717:AOLE_RS15615
uniprot id: D8JFB6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

436717:AOLE RS05665
gene id: 436717:AOLE_RS05665
uniprot id: D8JFS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS10915
gene id: 436717:AOLE_RS10915
uniprot id: D8JL24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

436717:AOLE RS06365
gene id: 436717:AOLE_RS06365
uniprot id: D8JGI4
names: Similarity
messages: Belongs to the GARS family.

436717:AOLE RS15205
gene id: 436717:AOLE_RS15205
uniprot id: D8JEQ1
names: Similarity
messages: Belongs to the GSP E family.

436717:AOLE RS02710
gene id: 436717:AOLE_RS02710
uniprot id: D8JNM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

436717:AOLE RS04545
gene id: 436717:AOLE_RS04545
uniprot id: D8JED2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

436717:AOLE RS02180
gene id: 436717:AOLE_RS02180
uniprot id: D8JMZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

436717:AOLE RS18755
gene id: 436717:AOLE_RS18755
uniprot id: D8JIL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

436717:AOLE RS05380
gene id: 436717:AOLE_RS05380
uniprot id: D8JF85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

436717:AOLE RS10335
gene id: 436717:AOLE_RS10335
uniprot id: D8JKC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

436717:AOLE RS17865
gene id: 436717:AOLE_RS17865
uniprot id: D8JHQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

436717:AOLE RS05625
gene id: 436717:AOLE_RS05625
uniprot id: D8JFR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS15325
gene id: 436717:AOLE_RS15325
uniprot id: D8JES6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS19425
gene id: 436717:AOLE_RS19425
uniprot id: D8JJC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS03675
gene id: 436717:AOLE_RS03675
uniprot id: D8JDH2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

436717:AOLE RS04715
gene id: 436717:AOLE_RS04715
uniprot id: D8JEG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

436717:AOLE RS02145
gene id: 436717:AOLE_RS02145
uniprot id: D8JMZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

436717:AOLE RS03855
gene id: 436717:AOLE_RS03855
uniprot id: D8JDL0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

436717:AOLE RS14705
gene id: 436717:AOLE_RS14705
uniprot id: D8JE16
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

436717:AOLE RS15895
gene id: 436717:AOLE_RS15895
uniprot id: D8JFH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

436717:AOLE RS06790
gene id: 436717:AOLE_RS06790
uniprot id: D8JH52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

436717:AOLE RS04790
gene id: 436717:AOLE_RS04790
uniprot id: D8JEW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

436717:AOLE RS04230
gene id: 436717:AOLE_RS04230
uniprot id: D8JE67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

436717:AOLE RS15250
gene id: 436717:AOLE_RS15250
uniprot id: D8JER0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

436717:AOLE RS16830
gene id: 436717:AOLE_RS16830
uniprot id: D8JGR6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

436717:AOLE RS02470
gene id: 436717:AOLE_RS02470
uniprot id: D8JN49
names: Similarity
messages: Belongs to the Gfa family.

436717:AOLE RS17165
gene id: 436717:AOLE_RS17165
uniprot id: D8JGY3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

436717:AOLE RS05110
gene id: 436717:AOLE_RS05110
uniprot id: D8JF29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

436717:AOLE RS15210
gene id: 436717:AOLE_RS15210
uniprot id: D8JEQ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS13655
gene id: 436717:AOLE_RS13655
uniprot id: D8JP44
names: Similarity
messages: Belongs to the class-I fumarase family.

436717:AOLE RS08655
gene id: 436717:AOLE_RS08655
uniprot id: D8JIY5
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

436717:AOLE RS04300
gene id: 436717:AOLE_RS04300
uniprot id: D8JE82
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

436717:AOLE RS08365
gene id: 436717:AOLE_RS08365
uniprot id: D8JIS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

436717:AOLE RS05805
gene id: 436717:AOLE_RS05805
uniprot id: D8JFV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

436717:AOLE RS05450
gene id: 436717:AOLE_RS05450
uniprot id: D8JFN1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

436717:AOLE RS19615
gene id: 436717:AOLE_RS19615
uniprot id: D8JKR0
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS16315
gene id: 436717:AOLE_RS16315
uniprot id: D8JG32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

436717:AOLE RS15195
gene id: 436717:AOLE_RS15195
uniprot id: D8JEP9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

436717:AOLE RS14320
gene id: 436717:AOLE_RS14320
uniprot id: D8JDT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

436717:AOLE RS07735
gene id: 436717:AOLE_RS07735
uniprot id: D8JI21
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS05550
gene id: 436717:AOLE_RS05550
uniprot id: D8JFQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

436717:AOLE RS09525
gene id: 436717:AOLE_RS09525
uniprot id: D8JJV9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

436717:AOLE RS18670
gene id: 436717:AOLE_RS18670
uniprot id: D8JIJ6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

436717:AOLE RS06695
gene id: 436717:AOLE_RS06695
uniprot id: D8JGP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

436717:AOLE RS11850
gene id: 436717:AOLE_RS11850
uniprot id: D8JLZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

436717:AOLE RS09830
gene id: 436717:AOLE_RS09830
uniprot id: D8JK22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

436717:AOLE RS12745
gene id: 436717:AOLE_RS12745
uniprot id: D8JMV9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

436717:AOLE RS04615
gene id: 436717:AOLE_RS04615
uniprot id: D8JEE6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

436717:AOLE RS00450
gene id: 436717:AOLE_RS00450
uniprot id: D8JKU9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

436717:AOLE RS13715
gene id: 436717:AOLE_RS13715
uniprot id: D8JP56
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

436717:AOLE RS02755
gene id: 436717:AOLE_RS02755
uniprot id: D8JNN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

436717:AOLE RS17000
gene id: 436717:AOLE_RS17000
uniprot id: D8JGV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

436717:AOLE RS13585
gene id: 436717:AOLE_RS13585
uniprot id: D8JP28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

436717:AOLE RS14620
gene id: 436717:AOLE_RS14620
uniprot id: D8JDZ9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

436717:AOLE RS17020
gene id: 436717:AOLE_RS17020
uniprot id: D8JGV4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

436717:AOLE RS03455
gene id: 436717:AOLE_RS03455
uniprot id: D8JDD1
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

436717:AOLE RS10975
gene id: 436717:AOLE_RS10975
uniprot id: D8JL36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

436717:AOLE RS14790
gene id: 436717:AOLE_RS14790
uniprot id: D8JEG7
names: Similarity
messages: Belongs to the DapA family.

436717:AOLE RS09575
gene id: 436717:AOLE_RS09575
uniprot id: D8JJX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS16745
gene id: 436717:AOLE_RS16745
uniprot id: D8JGB3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

436717:AOLE RS06305
gene id: 436717:AOLE_RS06305
uniprot id: D8JGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

436717:AOLE RS00245
gene id: 436717:AOLE_RS00245
uniprot id: D8JKQ7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

436717:AOLE RS11205
gene id: 436717:AOLE_RS11205
uniprot id: D8JL81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

436717:AOLE RS05590
gene id: 436717:AOLE_RS05590
uniprot id: D8JFQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

436717:AOLE RS05080
gene id: 436717:AOLE_RS05080
uniprot id: D8JF23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS08700
gene id: 436717:AOLE_RS08700
uniprot id: D8JIZ4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

436717:AOLE RS05005
gene id: 436717:AOLE_RS05005
uniprot id: D8JF08
names: Similarity
messages: Belongs to the group II decarboxylase family.

436717:AOLE RS02725
gene id: 436717:AOLE_RS02725
uniprot id: D8JNN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

436717:AOLE RS05500
gene id: 436717:AOLE_RS05500
uniprot id: D8JFP1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

436717:AOLE RS13660
gene id: 436717:AOLE_RS13660
uniprot id: D8JP45
names: Similarity
messages: Belongs to the class-I fumarase family.

436717:AOLE RS02390
gene id: 436717:AOLE_RS02390
uniprot id: D8JN38
names: Similarity
messages: Belongs to the PhoH family.

436717:AOLE RS01400
gene id: 436717:AOLE_RS01400
uniprot id: D8JM59
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

436717:AOLE RS05490
gene id: 436717:AOLE_RS05490
uniprot id: D8JFN9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS03555
gene id: 436717:AOLE_RS03555
uniprot id: D8JDE9
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS05390
gene id: 436717:AOLE_RS05390
uniprot id: D8JFM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

436717:AOLE RS04860
gene id: 436717:AOLE_RS04860
uniprot id: D8JEX8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

436717:AOLE RS09850
gene id: 436717:AOLE_RS09850
uniprot id: D8JK26
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

436717:AOLE RS09655
gene id: 436717:AOLE_RS09655
uniprot id: D8JJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

436717:AOLE RS06350
gene id: 436717:AOLE_RS06350
uniprot id: D8JGI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

436717:AOLE RS01705
gene id: 436717:AOLE_RS01705
uniprot id: D8JMB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

436717:AOLE RS17695
gene id: 436717:AOLE_RS17695
uniprot id: D8JHM3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

436717:AOLE RS05735
gene id: 436717:AOLE_RS05735
uniprot id: D8JFT6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

436717:AOLE RS05890
gene id: 436717:AOLE_RS05890
uniprot id: D8JFW6
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

436717:AOLE RS19300
gene id: 436717:AOLE_RS19300
uniprot id: D8JJA9
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

436717:AOLE RS06530
gene id: 436717:AOLE_RS06530
uniprot id: D8JGL6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

436717:AOLE RS15565
gene id: 436717:AOLE_RS15565
uniprot id: D8JFA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

436717:AOLE RS09315
gene id: 436717:AOLE_RS09315
uniprot id: D8JJQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

436717:AOLE RS04775
gene id: 436717:AOLE_RS04775
uniprot id: D8JEW1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

436717:AOLE RS09255
gene id: 436717:AOLE_RS09255
uniprot id: D8JJP2
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS04910
gene id: 436717:AOLE_RS04910
uniprot id: D8JEY9
names: Similarity
messages: Belongs to the PhzF family.

436717:AOLE RS14420
gene id: 436717:AOLE_RS14420
uniprot id: D8JDV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

436717:AOLE RS16185
gene id: 436717:AOLE_RS16185
uniprot id: D8JG06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

436717:AOLE RS05875
gene id: 436717:AOLE_RS05875
uniprot id: D8JFW3
names: Subcellular Location Annotation
messages: Cytoplasm

436717:AOLE RS19550
gene id: 436717:AOLE_RS19550
uniprot id: D8JJU0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

436717:AOLE RS12820
gene id: 436717:AOLE_RS12820
uniprot id: D8JN98
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS12360
gene id: 436717:AOLE_RS12360
uniprot id: D8JMN0
names: Similarity
messages: Belongs to the VgrG protein family.

436717:AOLE RS15160
gene id: 436717:AOLE_RS15160
uniprot id: D8JEP2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

436717:AOLE RS11435
gene id: 436717:AOLE_RS11435
uniprot id: D8JLC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Belongs to the heat shock protein 70 family.
messages: Membrane

436717:AOLE RS15830
gene id: 436717:AOLE_RS15830
uniprot id: D8JFG1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS02280
gene id: 436717:AOLE_RS02280
uniprot id: D8JN20
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS20825
gene id: 436717:AOLE_RS20825
uniprot id: D8JHP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

436717:AOLE RS12005
gene id: 436717:AOLE_RS12005
uniprot id: D8JM26
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS15345
gene id: 436717:AOLE_RS15345
uniprot id: D8JET0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

436717:AOLE RS16615
gene id: 436717:AOLE_RS16615
uniprot id: D8JG87
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

436717:AOLE RS16625
gene id: 436717:AOLE_RS16625
uniprot id: D8JG89
names: Similarity
messages: Belongs to the hyi family.

436717:AOLE RS10685
gene id: 436717:AOLE_RS10685
uniprot id: D8JKJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

436717:AOLE RS00810
gene id: 436717:AOLE_RS00810
uniprot id: D8JLF7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS17575
gene id: 436717:AOLE_RS17575
uniprot id: D8JHJ9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

436717:AOLE RS10910
gene id: 436717:AOLE_RS10910
uniprot id: D8JL23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

436717:AOLE RS19110
gene id: 436717:AOLE_RS19110
uniprot id: D8JJ70
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

436717:AOLE RS10340
gene id: 436717:AOLE_RS10340
uniprot id: D8JKC7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

436717:AOLE RS16095
gene id: 436717:AOLE_RS16095
uniprot id: D8JFL4
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS09365
gene id: 436717:AOLE_RS09365
uniprot id: D8JJR6
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS14860
gene id: 436717:AOLE_RS14860
uniprot id: D8JEI1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

436717:AOLE RS05360
gene id: 436717:AOLE_RS05360
uniprot id: D8JF81
names: Similarity
messages: Belongs to the TrpC family.

436717:AOLE RS04405
gene id: 436717:AOLE_RS04405
uniprot id: D8JEA3
names: Similarity
messages: Belongs to the peptidase S49 family.

436717:AOLE RS19160
gene id: 436717:AOLE_RS19160
uniprot id: D8JJ80
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS00005
gene id: 436717:AOLE_RS00005
uniprot id: D8JKL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

436717:AOLE RS02895
gene id: 436717:AOLE_RS02895
uniprot id: D8JNR3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS04740
gene id: 436717:AOLE_RS04740
uniprot id: D8JEV4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

436717:AOLE RS15320
gene id: 436717:AOLE_RS15320
uniprot id: D8JES5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

436717:AOLE RS13340
gene id: 436717:AOLE_RS13340
uniprot id: D8JNK0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS03360
gene id: 436717:AOLE_RS03360
uniprot id: D8JP01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS03125
gene id: 436717:AOLE_RS03125
uniprot id: D8JNW0
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS05530
gene id: 436717:AOLE_RS05530
uniprot id: D8JFP7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

436717:AOLE RS05145
gene id: 436717:AOLE_RS05145
uniprot id: D8JF36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

436717:AOLE RS07225
gene id: 436717:AOLE_RS07225
uniprot id: D8JHE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

436717:AOLE RS13740
gene id: 436717:AOLE_RS13740
uniprot id: D8JP61
names: Subcellular Location Annotation
messages: Membrane

436717:AOLE RS05400
gene id: 436717:AOLE_RS05400
uniprot id: D8JFM4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

436717:AOLE RS09535
gene id: 436717:AOLE_RS09535
uniprot id: D8JJW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

436717:AOLE RS15890
gene id: 436717:AOLE_RS15890
uniprot id: D8JFH3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

436717:AOLE RS01505
gene id: 436717:AOLE_RS01505
uniprot id: D8JM76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS10065
gene id: 436717:AOLE_RS10065
uniprot id: D8JK71
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

436717:AOLE RS17285
gene id: 436717:AOLE_RS17285
uniprot id: D8JH07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

436717:AOLE RS13565
gene id: 436717:AOLE_RS13565
uniprot id: D8JP24
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

436717:AOLE RS15940
gene id: 436717:AOLE_RS15940
uniprot id: D8JFI3
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

436717:AOLE RS02560
gene id: 436717:AOLE_RS02560
uniprot id: D8JN67
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

436717:AOLE RS12365
gene id: 436717:AOLE_RS12365
uniprot id: D8JMN1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS12015
gene id: 436717:AOLE_RS12015
uniprot id: D8JM28
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

436717:AOLE RS11475
gene id: 436717:AOLE_RS11475
uniprot id: D8JLR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS05975
gene id: 436717:AOLE_RS05975
uniprot id: D8JFY3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS16105
gene id: 436717:AOLE_RS16105
uniprot id: D8JFL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS06700
gene id: 436717:AOLE_RS06700
uniprot id: D8JGQ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

436717:AOLE RS15560
gene id: 436717:AOLE_RS15560
uniprot id: D8JFA5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

436717:AOLE RS15255
gene id: 436717:AOLE_RS15255
uniprot id: D8JER1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

436717:AOLE RS05710
gene id: 436717:AOLE_RS05710
uniprot id: D8JFT1
names: Similarity
messages: Belongs to the GSP E family.

436717:AOLE RS10145
gene id: 436717:AOLE_RS10145
uniprot id: D8JK88
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

436717:AOLE RS08750
gene id: 436717:AOLE_RS08750
uniprot id: D8JJ04
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS15860
gene id: 436717:AOLE_RS15860
uniprot id: D8JFG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

436717:AOLE RS17555
gene id: 436717:AOLE_RS17555
uniprot id: D8JHJ5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

436717:AOLE RS18585
gene id: 436717:AOLE_RS18585
uniprot id: D8JIH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

436717:AOLE RS18570
gene id: 436717:AOLE_RS18570
uniprot id: D8JIH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

436717:AOLE RS04915
gene id: 436717:AOLE_RS04915
uniprot id: D8JEZ0
names: Similarity
messages: Belongs to the peptidase M16 family.

436717:AOLE RS17980
gene id: 436717:AOLE_RS17980
uniprot id: D8JHS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

436717:AOLE RS00905
gene id: 436717:AOLE_RS00905
uniprot id: D8JLH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

436717:AOLE RS03110
gene id: 436717:AOLE_RS03110
uniprot id: D8JNV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

436717:AOLE RS02510
gene id: 436717:AOLE_RS02510
uniprot id: D8JN57
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

436717:AOLE RS13640
gene id: 436717:AOLE_RS13640
uniprot id: D8JP41
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

436717:AOLE RS06720
gene id: 436717:AOLE_RS06720
uniprot id: D8JGQ4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

436717:AOLE RS12205
gene id: 436717:AOLE_RS12205
uniprot id: D8JMJ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

436717:AOLE RS06035
gene id: 436717:AOLE_RS06035
uniprot id: D8JFZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

436717:AOLE RS11990
gene id: 436717:AOLE_RS11990
uniprot id: D8JM23
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

436717:AOLE RS06465
gene id: 436717:AOLE_RS06465
uniprot id: D8JGK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

436717:AOLE RS04015
gene id: 436717:AOLE_RS04015
uniprot id: D8JDN6
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

436717:AOLE RS10895
gene id: 436717:AOLE_RS10895
uniprot id: D8JL20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

436717:AOLE RS04595
gene id: 436717:AOLE_RS04595
uniprot id: D8JEE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

436717:AOLE RS02960
gene id: 436717:AOLE_RS02960
uniprot id: D8JNS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

436717:AOLE RS05955
gene id: 436717:AOLE_RS05955
uniprot id: D8JFX9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

436717:AOLE RS02680
gene id: 436717:AOLE_RS02680
uniprot id: D8JN86
names: Similarity
messages: Belongs to the thioredoxin family.

436717:AOLE RS05595
gene id: 436717:AOLE_RS05595
uniprot id: D8JFQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane