426114:THI RS16705
gene id: 426114:THI_RS16705
uniprot id: D6CNT0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

426114:THI RS09545
gene id: 426114:THI_RS09545
uniprot id: D6CTX3
names: Similarity
messages: Belongs to the asparagine synthetase family.

426114:THI RS06830
gene id: 426114:THI_RS06830
uniprot id: D6CQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

426114:THI RS05025
gene id: 426114:THI_RS05025
uniprot id: D6CL51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS10095
gene id: 426114:THI_RS10095
uniprot id: D6CU83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

426114:THI RS08565
gene id: 426114:THI_RS08565
uniprot id: D6CTB9
names: Similarity
messages: Belongs to the HSP15 family.

426114:THI RS13955
gene id: 426114:THI_RS13955
uniprot id: D6CM52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

426114:THI RS15250
gene id: 426114:THI_RS15250
uniprot id: D6CMX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

426114:THI RS00920
gene id: 426114:THI_RS00920
uniprot id: D6CQR3
names: Similarity
messages: Belongs to the glutamine synthetase family.

426114:THI RS11365
gene id: 426114:THI_RS11365
uniprot id: D6CUY6
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

426114:THI RS16285
gene id: 426114:THI_RS16285
uniprot id: D6CNI7
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS02660
gene id: 426114:THI_RS02660
uniprot id: D6CRR8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

426114:THI RS06105
gene id: 426114:THI_RS06105
uniprot id: D6CPU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

426114:THI RS03340
gene id: 426114:THI_RS03340
uniprot id: D6CKI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

426114:THI RS08320
gene id: 426114:THI_RS08320
uniprot id: D6CT69
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

426114:THI RS15145
gene id: 426114:THI_RS15145
uniprot id: D6CMV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

426114:THI RS07725
gene id: 426114:THI_RS07725
uniprot id: D6CSU6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

426114:THI RS13680
gene id: 426114:THI_RS13680
uniprot id: D6CLZ4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

426114:THI RS02930
gene id: 426114:THI_RS02930
uniprot id: D6CRX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS13855
gene id: 426114:THI_RS13855
uniprot id: D6CM31
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

426114:THI RS15215
gene id: 426114:THI_RS15215
uniprot id: D6CMW8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

426114:THI RS06130
gene id: 426114:THI_RS06130
uniprot id: D6CPV3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

426114:THI RS03830
gene id: 426114:THI_RS03830
uniprot id: D6CKT4
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

426114:THI RS05445
gene id: 426114:THI_RS05445
uniprot id: D6CPF8
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS03630
gene id: 426114:THI_RS03630
uniprot id: D6CKP6
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

426114:THI RS03990
gene id: 426114:THI_RS03990
uniprot id: D6CS57
names: Similarity
messages: Belongs to the DEAD box helicase family.

426114:THI RS05465
gene id: 426114:THI_RS05465
uniprot id: D6CPG2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

426114:THI RS00115
gene id: 426114:THI_RS00115
uniprot id: D6CVL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

426114:THI RS07515
gene id: 426114:THI_RS07515
uniprot id: D6CSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

426114:THI RS15945
gene id: 426114:THI_RS15945
uniprot id: D6CNB3
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS01820
gene id: 426114:THI_RS01820
uniprot id: D6CR95
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS05005
gene id: 426114:THI_RS05005
uniprot id: D6CL47
names: Similarity
messages: Belongs to the MlaA family.

426114:THI RS13920
gene id: 426114:THI_RS13920
uniprot id: D6CM45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

426114:THI RS06335
gene id: 426114:THI_RS06335
uniprot id: D6CPZ4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

426114:THI RS12385
gene id: 426114:THI_RS12385
uniprot id: D6CVJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

426114:THI RS03930
gene id: 426114:THI_RS03930
uniprot id: D6CKV5
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS07405
gene id: 426114:THI_RS07405
uniprot id: D6CSN3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

426114:THI RS08695
gene id: 426114:THI_RS08695
uniprot id: D6CTE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

426114:THI RS17250
gene id: 426114:THI_RS17250
uniprot id: D6CP42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS01880
gene id: 426114:THI_RS01880
uniprot id: D6CRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

426114:THI RS13705
gene id: 426114:THI_RS13705
uniprot id: D6CLZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

426114:THI RS01735
gene id: 426114:THI_RS01735
uniprot id: D6CR79
names: Similarity
messages: Belongs to the acylphosphatase family.

426114:THI RS03325
gene id: 426114:THI_RS03325
uniprot id: D6CKI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

426114:THI RS06495
gene id: 426114:THI_RS06495
uniprot id: D6CQ28
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

426114:THI RS16760
gene id: 426114:THI_RS16760
uniprot id: D6CNU3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

426114:THI RS10830
gene id: 426114:THI_RS10830
uniprot id: D6CUM6
names: Similarity
messages: Belongs to the GSP E family.

426114:THI RS14845
gene id: 426114:THI_RS14845
uniprot id: D6CMP4
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

426114:THI RS15930
gene id: 426114:THI_RS15930
uniprot id: D6CNB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

426114:THI RS12175
gene id: 426114:THI_RS12175
uniprot id: D6CVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

426114:THI RS14385
gene id: 426114:THI_RS14385
uniprot id: D6CME6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

426114:THI RS00895
gene id: 426114:THI_RS00895
uniprot id: D6CQQ8
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS08605
gene id: 426114:THI_RS08605
uniprot id: D6CTC7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

426114:THI RS04290
gene id: 426114:THI_RS04290
uniprot id: D6CSC6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

426114:THI RS16105
gene id: 426114:THI_RS16105
uniprot id: D6CNF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

426114:THI RS07615
gene id: 426114:THI_RS07615
uniprot id: D6CSS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

426114:THI RS05475
gene id: 426114:THI_RS05475
uniprot id: D6CPG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

426114:THI RS02380
gene id: 426114:THI_RS02380
uniprot id: D6CRL0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

426114:THI RS05060
gene id: 426114:THI_RS05060
uniprot id: D6CL58
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

426114:THI RS17615
gene id: 426114:THI_RS17615
uniprot id: D6CPB6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS13520
gene id: 426114:THI_RS13520
uniprot id: D6CLW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

426114:THI RS15580
gene id: 426114:THI_RS15580
uniprot id: D6CN42
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

426114:THI RS13685
gene id: 426114:THI_RS13685
uniprot id: D6CLZ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

426114:THI RS10395
gene id: 426114:THI_RS10395
uniprot id: D6CUD9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

426114:THI RS00620
gene id: 426114:THI_RS00620
uniprot id: D6CQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family. CsoSCA subfamily.
messages: Carboxysome

426114:THI RS07380
gene id: 426114:THI_RS07380
uniprot id: D6CSM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

426114:THI RS04645
gene id: 426114:THI_RS04645
uniprot id: D6CKX3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

426114:THI RS10425
gene id: 426114:THI_RS10425
uniprot id: D6CUE5
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS05635
gene id: 426114:THI_RS05635
uniprot id: D6CPJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

426114:THI RS05925
gene id: 426114:THI_RS05925
uniprot id: D6CPQ8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS01245
gene id: 426114:THI_RS01245
uniprot id: D6CQX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

426114:THI RS10100
gene id: 426114:THI_RS10100
uniprot id: D6CU84
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

426114:THI RS12075
gene id: 426114:THI_RS12075
uniprot id: D6CVD2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

426114:THI RS11985
gene id: 426114:THI_RS11985
uniprot id: D6CVB4
names: Similarity
messages: Belongs to the MipA/OmpV family.

426114:THI RS07780
gene id: 426114:THI_RS07780
uniprot id: D6CSV7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

426114:THI RS06740
gene id: 426114:THI_RS06740
uniprot id: D6CQ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

426114:THI RS09815
gene id: 426114:THI_RS09815
uniprot id: D6CU27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

426114:THI RS05490
gene id: 426114:THI_RS05490
uniprot id: D6CPG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS11280
gene id: 426114:THI_RS11280
uniprot id: D6CUW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

426114:THI RS05855
gene id: 426114:THI_RS05855
uniprot id: D6CPP4
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

426114:THI RS05035
gene id: 426114:THI_RS05035
uniprot id: D6CL53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS05365
gene id: 426114:THI_RS05365
uniprot id: D6CPE2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

426114:THI RS15260
gene id: 426114:THI_RS15260
uniprot id: D6CMX7
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS15840
gene id: 426114:THI_RS15840
uniprot id: D6CN96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

426114:THI RS04375
gene id: 426114:THI_RS04375
uniprot id: D6CSE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

426114:THI RS12090
gene id: 426114:THI_RS12090
uniprot id: D6CVD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

426114:THI RS05565
gene id: 426114:THI_RS05565
uniprot id: D6CPI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

426114:THI RS01500
gene id: 426114:THI_RS01500
uniprot id: D6CR33
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS15245
gene id: 426114:THI_RS15245
uniprot id: D6CMX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

426114:THI RS07355
gene id: 426114:THI_RS07355
uniprot id: D6CSM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

426114:THI RS11745
gene id: 426114:THI_RS11745
uniprot id: D6CV66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

426114:THI RS05870
gene id: 426114:THI_RS05870
uniprot id: D6CPP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

426114:THI RS13990
gene id: 426114:THI_RS13990
uniprot id: D6CM60
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

426114:THI RS10120
gene id: 426114:THI_RS10120
uniprot id: D6CU88
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS05880
gene id: 426114:THI_RS05880
uniprot id: D6CPP9
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

426114:THI RS09985
gene id: 426114:THI_RS09985
uniprot id: D6CU61
names: Similarity
messages: Belongs to the peptidase S66 family.

426114:THI RS07060
gene id: 426114:THI_RS07060
uniprot id: D6CQF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

426114:THI RS01295
gene id: 426114:THI_RS01295
uniprot id: D6CQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

426114:THI RS05225
gene id: 426114:THI_RS05225
uniprot id: D6CL92
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

426114:THI RS10215
gene id: 426114:THI_RS10215
uniprot id: D6CUA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

426114:THI RS05875
gene id: 426114:THI_RS05875
uniprot id: D6CPP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

426114:THI RS13975
gene id: 426114:THI_RS13975
uniprot id: D6CM57
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

426114:THI RS11780
gene id: 426114:THI_RS11780
uniprot id: D6CV73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

426114:THI RS04995
gene id: 426114:THI_RS04995
uniprot id: D6CL45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS07400
gene id: 426114:THI_RS07400
uniprot id: D6CSN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

426114:THI RS08170
gene id: 426114:THI_RS08170
uniprot id: D6CT39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

426114:THI RS08150
gene id: 426114:THI_RS08150
uniprot id: D6CT34
names: Similarity
messages: Belongs to the universal stress protein A family.

426114:THI RS05285
gene id: 426114:THI_RS05285
uniprot id: D6CPC7
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

426114:THI RS12415
gene id: 426114:THI_RS12415
uniprot id: D6CVJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

426114:THI RS15500
gene id: 426114:THI_RS15500
uniprot id: D6CN26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

426114:THI RS07000
gene id: 426114:THI_RS07000
uniprot id: D6CQE0
names: Similarity
messages: Belongs to the MotB family.

426114:THI RS14725
gene id: 426114:THI_RS14725
uniprot id: D6CML5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

426114:THI RS09610
gene id: 426114:THI_RS09610
uniprot id: D6CTY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

426114:THI RS11525
gene id: 426114:THI_RS11525
uniprot id: D6CV20
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS06120
gene id: 426114:THI_RS06120
uniprot id: D6CPV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

426114:THI RS07690
gene id: 426114:THI_RS07690
uniprot id: D6CSU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS05485
gene id: 426114:THI_RS05485
uniprot id: D6CPG6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

426114:THI RS12130
gene id: 426114:THI_RS12130
uniprot id: D6CVE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

426114:THI RS11345
gene id: 426114:THI_RS11345
uniprot id: D6CUY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

426114:THI RS06705
gene id: 426114:THI_RS06705
uniprot id: D6CQ81
names: Subcellular Location Annotation
messages: Cell inner membrane

426114:THI RS06285
gene id: 426114:THI_RS06285
uniprot id: D6CPQ8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS02990
gene id: 426114:THI_RS02990
uniprot id: D6CRZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

426114:THI RS07565
gene id: 426114:THI_RS07565
uniprot id: D6CSR6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

426114:THI RS16530
gene id: 426114:THI_RS16530
uniprot id: D6CNP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

426114:THI RS01730
gene id: 426114:THI_RS01730
uniprot id: D6CR78
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

426114:THI RS04755
gene id: 426114:THI_RS04755
uniprot id: D6CKZ5
names: Similarity
messages: Belongs to the pyruvate kinase family.

426114:THI RS16260
gene id: 426114:THI_RS16260
uniprot id: D6CNI2
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS04425
gene id: 426114:THI_RS04425
uniprot id: D6CSF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

426114:THI RS09025
gene id: 426114:THI_RS09025
uniprot id: D6CTL2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS01745
gene id: 426114:THI_RS01745
uniprot id: D6CR81
names: Similarity
messages: Belongs to the GSP E family.

426114:THI RS00525
gene id: 426114:THI_RS00525
uniprot id: D6CQI4
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

426114:THI RS11845
gene id: 426114:THI_RS11845
uniprot id: D6CV86
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS06170
gene id: 426114:THI_RS06170
uniprot id: D6CPW2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

426114:THI RS08300
gene id: 426114:THI_RS08300
uniprot id: D6CT65
names: Similarity
messages: Belongs to the glutamine synthetase family.

426114:THI RS08660
gene id: 426114:THI_RS08660
uniprot id: D6CTD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

426114:THI RS10070
gene id: 426114:THI_RS10070
uniprot id: D6CU78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS05695
gene id: 426114:THI_RS05695
uniprot id: D6CPL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS15295
gene id: 426114:THI_RS15295
uniprot id: D6CMY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

426114:THI RS12465
gene id: 426114:THI_RS12465
uniprot id: D6CLA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

426114:THI RS11190
gene id: 426114:THI_RS11190
uniprot id: D6CUV1
names: Similarity
messages: Belongs to the threonine synthase family.

426114:THI RS00260
gene id: 426114:THI_RS00260
uniprot id: D6CVN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

426114:THI RS14015
gene id: 426114:THI_RS14015
uniprot id: D6CM65
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

426114:THI RS00485
gene id: 426114:THI_RS00485
uniprot id: D6CQH5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

426114:THI RS10565
gene id: 426114:THI_RS10565
uniprot id: D6CUH3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

426114:THI RS11395
gene id: 426114:THI_RS11395
uniprot id: D6CUZ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

426114:THI RS09910
gene id: 426114:THI_RS09910
uniprot id: D6CU46
names: Similarity
messages: Belongs to the thioredoxin family.

426114:THI RS16565
gene id: 426114:THI_RS16565
uniprot id: D6CNP9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

426114:THI RS16365
gene id: 426114:THI_RS16365
uniprot id: D6CNK5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

426114:THI RS10550
gene id: 426114:THI_RS10550
uniprot id: D6CUH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

426114:THI RS09605
gene id: 426114:THI_RS09605
uniprot id: D6CTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

426114:THI RS10680
gene id: 426114:THI_RS10680
uniprot id: D6CPQ8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS06710
gene id: 426114:THI_RS06710
uniprot id: D6CQ82
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

426114:THI RS09495
gene id: 426114:THI_RS09495
uniprot id: D6CTW4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

426114:THI RS07075
gene id: 426114:THI_RS07075
uniprot id: D6CQF5
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

426114:THI RS13245
gene id: 426114:THI_RS13245
uniprot id: D6CLQ7
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

426114:THI RS10005
gene id: 426114:THI_RS10005
uniprot id: D6CU65
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

426114:THI RS05400
gene id: 426114:THI_RS05400
uniprot id: D6CPE9
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

426114:THI RS06735
gene id: 426114:THI_RS06735
uniprot id: D6CQ87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

426114:THI RS07395
gene id: 426114:THI_RS07395
uniprot id: D6CSN1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

426114:THI RS12395
gene id: 426114:THI_RS12395
uniprot id: D6CVJ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS02450
gene id: 426114:THI_RS02450
uniprot id: D6CRM6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

426114:THI RS01805
gene id: 426114:THI_RS01805
uniprot id: D6CR92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

426114:THI RS07605
gene id: 426114:THI_RS07605
uniprot id: D6CSS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

426114:THI RS07120
gene id: 426114:THI_RS07120
uniprot id: D6CQG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

426114:THI RS02075
gene id: 426114:THI_RS02075
uniprot id: D6CRE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS03420
gene id: 426114:THI_RS03420
uniprot id: D6CKK3
names: Similarity
messages: Belongs to the type IA topoisomerase family.

426114:THI RS03035
gene id: 426114:THI_RS03035
uniprot id: D6CS00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS03615
gene id: 426114:THI_RS03615
uniprot id: D6CKP3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

426114:THI RS06400
gene id: 426114:THI_RS06400
uniprot id: D6CQ07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

426114:THI RS10305
gene id: 426114:THI_RS10305
uniprot id: D6CUC2
names: Similarity
messages: Belongs to the universal stress protein A family.

426114:THI RS13340
gene id: 426114:THI_RS13340
uniprot id: D6CLS8
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS11155
gene id: 426114:THI_RS11155
uniprot id: D6CUU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

426114:THI RS05750
gene id: 426114:THI_RS05750
uniprot id: D6CPM3
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

426114:THI RS15860
gene id: 426114:THI_RS15860
uniprot id: D6CNA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

426114:THI RS09855
gene id: 426114:THI_RS09855
uniprot id: D6CU35
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS06080
gene id: 426114:THI_RS06080
uniprot id: D6CPU3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

426114:THI RS15110
gene id: 426114:THI_RS15110
uniprot id: D6CMU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS14245
gene id: 426114:THI_RS14245
uniprot id: D6CMB7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

426114:THI RS06340
gene id: 426114:THI_RS06340
uniprot id: D6CPZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

426114:THI RS06725
gene id: 426114:THI_RS06725
uniprot id: D6CQ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

426114:THI RS01410
gene id: 426114:THI_RS01410
uniprot id: D6CR15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

426114:THI RS02120
gene id: 426114:THI_RS02120
uniprot id: D6CRF5
names: Similarity
messages: Belongs to the aspartokinase family.

426114:THI RS03545
gene id: 426114:THI_RS03545
uniprot id: D6CKM9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

426114:THI RS06095
gene id: 426114:THI_RS06095
uniprot id: D6CPU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS01875
gene id: 426114:THI_RS01875
uniprot id: D6CRA7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS01260
gene id: 426114:THI_RS01260
uniprot id: D6CQY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

426114:THI RS13715
gene id: 426114:THI_RS13715
uniprot id: D6CM01
names: Similarity
messages: Belongs to the GcvT family.

426114:THI RS10710
gene id: 426114:THI_RS10710
uniprot id: D6CUK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

426114:THI RS11125
gene id: 426114:THI_RS11125
uniprot id: D6CUT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

426114:THI RS09755
gene id: 426114:THI_RS09755
uniprot id: D6CU15
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

426114:THI RS01900
gene id: 426114:THI_RS01900
uniprot id: D6CRB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

426114:THI RS02170
gene id: 426114:THI_RS02170
uniprot id: D6CRG5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

426114:THI RS03575
gene id: 426114:THI_RS03575
uniprot id: D6CKN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

426114:THI RS03225
gene id: 426114:THI_RS03225
uniprot id: D6CS39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

426114:THI RS04150
gene id: 426114:THI_RS04150
uniprot id: D6CS92
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

426114:THI RS03085
gene id: 426114:THI_RS03085
uniprot id: D6CS10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

426114:THI RS15875
gene id: 426114:THI_RS15875
uniprot id: D6CNA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

426114:THI RS04305
gene id: 426114:THI_RS04305
uniprot id: D6CPQ8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS07800
gene id: 426114:THI_RS07800
uniprot id: D6CSW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

426114:THI RS16300
gene id: 426114:THI_RS16300
uniprot id: D6CNJ1
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS10160
gene id: 426114:THI_RS10160
uniprot id: D6CU96
names: Similarity
messages: Belongs to the peptidase M1 family.

426114:THI RS00605
gene id: 426114:THI_RS00605
uniprot id: D6CQK0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

426114:THI RS17775
gene id: 426114:THI_RS17775
uniprot id: D6CVT3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

426114:THI RS17200
gene id: 426114:THI_RS17200
uniprot id: D6CP32
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

426114:THI RS08395
gene id: 426114:THI_RS08395
uniprot id: D6CT84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

426114:THI RS16225
gene id: 426114:THI_RS16225
uniprot id: D6CNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

426114:THI RS00330
gene id: 426114:THI_RS00330
uniprot id: D6CVQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

426114:THI RS00320
gene id: 426114:THI_RS00320
uniprot id: D6CVQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

426114:THI RS09505
gene id: 426114:THI_RS09505
uniprot id: D6CTW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

426114:THI RS15795
gene id: 426114:THI_RS15795
uniprot id: D6CN87
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

426114:THI RS15255
gene id: 426114:THI_RS15255
uniprot id: D6CMX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

426114:THI RS00520
gene id: 426114:THI_RS00520
uniprot id: D6CQI2
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

426114:THI RS03560
gene id: 426114:THI_RS03560
uniprot id: D6CKN2
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

426114:THI RS12170
gene id: 426114:THI_RS12170
uniprot id: D6CVF1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS04370
gene id: 426114:THI_RS04370
uniprot id: D6CSE2
names: Similarity
messages: Belongs to the peptidase S41A family.

426114:THI RS00715
gene id: 426114:THI_RS00715
uniprot id: D6CQM2
names: Similarity
messages: Belongs to the phosphoribulokinase family.

426114:THI RS09330
gene id: 426114:THI_RS09330
uniprot id: D6CTS7
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS02300
gene id: 426114:THI_RS02300
uniprot id: D6CRJ4
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

426114:THI RS12625
gene id: 426114:THI_RS12625
uniprot id: D6CLD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

426114:THI RS12190
gene id: 426114:THI_RS12190
uniprot id: D6CVF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

426114:THI RS09135
gene id: 426114:THI_RS09135
uniprot id: D6CTN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

426114:THI RS13565
gene id: 426114:THI_RS13565
uniprot id: D6CLX2
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

426114:THI RS11795
gene id: 426114:THI_RS11795
uniprot id: D6CV77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS10025
gene id: 426114:THI_RS10025
uniprot id: D6CU69
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

426114:THI RS01855
gene id: 426114:THI_RS01855
uniprot id: D6CRA3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

426114:THI RS11675
gene id: 426114:THI_RS11675
uniprot id: D6CPQ8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS15240
gene id: 426114:THI_RS15240
uniprot id: D6CMX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

426114:THI RS10685
gene id: 426114:THI_RS10685
uniprot id: D6CUJ5
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

426114:THI RS15815
gene id: 426114:THI_RS15815
uniprot id: D6CN91
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

426114:THI RS01475
gene id: 426114:THI_RS01475
uniprot id: D6CR28
names: Similarity
messages: Belongs to the UPF0235 family.

426114:THI RS04340
gene id: 426114:THI_RS04340
uniprot id: D6CSD6
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS05805
gene id: 426114:THI_RS05805
uniprot id: D6CPN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

426114:THI RS11765
gene id: 426114:THI_RS11765
uniprot id: D6CV70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

426114:THI RS00700
gene id: 426114:THI_RS00700
uniprot id: D6CQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

426114:THI RS02320
gene id: 426114:THI_RS02320
uniprot id: D6CRJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

426114:THI RS05830
gene id: 426114:THI_RS05830
uniprot id: D6CPN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

426114:THI RS07635
gene id: 426114:THI_RS07635
uniprot id: D6CSS9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

426114:THI RS00495
gene id: 426114:THI_RS00495
uniprot id: D6CQH7
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

426114:THI RS12035
gene id: 426114:THI_RS12035
uniprot id: D6CVC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

426114:THI RS14930
gene id: 426114:THI_RS14930
uniprot id: D6CMR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

426114:THI RS08505
gene id: 426114:THI_RS08505
uniprot id: D6CTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

426114:THI RS01790
gene id: 426114:THI_RS01790
uniprot id: D6CR90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

426114:THI RS09960
gene id: 426114:THI_RS09960
uniprot id: D6CU57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

426114:THI RS05915
gene id: 426114:THI_RS05915
uniprot id: D6CPQ6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

426114:THI RS11195
gene id: 426114:THI_RS11195
uniprot id: D6CUV2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

426114:THI RS06025
gene id: 426114:THI_RS06025
uniprot id: D6CPT2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

426114:THI RS05150
gene id: 426114:THI_RS05150
uniprot id: D6CL77
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

426114:THI RS08345
gene id: 426114:THI_RS08345
uniprot id: D6CT74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

426114:THI RS17255
gene id: 426114:THI_RS17255
uniprot id: D6CP43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

426114:THI RS09195
gene id: 426114:THI_RS09195
uniprot id: D6CTP9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

426114:THI RS17890
gene id: 426114:THI_RS17890
uniprot id: D6CVW2
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

426114:THI RS17145
gene id: 426114:THI_RS17145
uniprot id: D6CNA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

426114:THI RS06280
gene id: 426114:THI_RS06280
uniprot id: D6CPQ7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

426114:THI RS12790
gene id: 426114:THI_RS12790
uniprot id: D6CLG4
names: Similarity
messages: Belongs to the fabD family.

426114:THI RS14500
gene id: 426114:THI_RS14500
uniprot id: D6CMH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

426114:THI RS08035
gene id: 426114:THI_RS08035
uniprot id: D6CT11
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

426114:THI RS14175
gene id: 426114:THI_RS14175
uniprot id: D6CMA0
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

426114:THI RS16740
gene id: 426114:THI_RS16740
uniprot id: D6CNT9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

426114:THI RS17105
gene id: 426114:THI_RS17105
uniprot id: D6CP17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

426114:THI RS17125
gene id: 426114:THI_RS17125
uniprot id: D6CP21
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

426114:THI RS07770
gene id: 426114:THI_RS07770
uniprot id: D6CSV4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS01425
gene id: 426114:THI_RS01425
uniprot id: D6CR18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

426114:THI RS07535
gene id: 426114:THI_RS07535
uniprot id: D6CSQ8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

426114:THI RS15495
gene id: 426114:THI_RS15495
uniprot id: D6CN25
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

426114:THI RS00965
gene id: 426114:THI_RS00965
uniprot id: D6CQS2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

426114:THI RS04390
gene id: 426114:THI_RS04390
uniprot id: D6CSE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

426114:THI RS00065
gene id: 426114:THI_RS00065
uniprot id: D6CKG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS06730
gene id: 426114:THI_RS06730
uniprot id: D6CQ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

426114:THI RS08765
gene id: 426114:THI_RS08765
uniprot id: D6CTF9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

426114:THI RS15920
gene id: 426114:THI_RS15920
uniprot id: D6CNA8
names: Similarity
messages: Belongs to the PhoH family.

426114:THI RS02085
gene id: 426114:THI_RS02085
uniprot id: D6CRE8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

426114:THI RS02430
gene id: 426114:THI_RS02430
uniprot id: D6CRM1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

426114:THI RS12320
gene id: 426114:THI_RS12320
uniprot id: D6CVI1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

426114:THI RS15630
gene id: 426114:THI_RS15630
uniprot id: D6CN52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS03280
gene id: 426114:THI_RS03280
uniprot id: D6CKH4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS11600
gene id: 426114:THI_RS11600
uniprot id: D6CV35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

426114:THI RS05055
gene id: 426114:THI_RS05055
uniprot id: D6CL57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

426114:THI RS06855
gene id: 426114:THI_RS06855
uniprot id: D6CQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

426114:THI RS04105
gene id: 426114:THI_RS04105
uniprot id: D6CS81
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

426114:THI RS07930
gene id: 426114:THI_RS07930
uniprot id: D6CSY7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

426114:THI RS09325
gene id: 426114:THI_RS09325
uniprot id: D6CTS6
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

426114:THI RS10485
gene id: 426114:THI_RS10485
uniprot id: A0A8I1SYT4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS00220
gene id: 426114:THI_RS00220
uniprot id: D6CVN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

426114:THI RS14715
gene id: 426114:THI_RS14715
uniprot id: D6CML3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

426114:THI RS14940
gene id: 426114:THI_RS14940
uniprot id: D6CMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

426114:THI RS00595
gene id: 426114:THI_RS00595
uniprot id: D6CQJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

426114:THI RS16175
gene id: 426114:THI_RS16175
uniprot id: D6CNG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

426114:THI RS09680
gene id: 426114:THI_RS09680
uniprot id: A0A8I1MY51
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS13195
gene id: 426114:THI_RS13195
uniprot id: D6CLP7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

426114:THI RS15410
gene id: 426114:THI_RS15410
uniprot id: D6CN07
names: PTM
messages: Binds 1 heme group per subunit.

426114:THI RS15365
gene id: 426114:THI_RS15365
uniprot id: D6CMZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS12635
gene id: 426114:THI_RS12635
uniprot id: D6CLD3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS15105
gene id: 426114:THI_RS15105
uniprot id: D6CMU6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

426114:THI RS11135
gene id: 426114:THI_RS11135
uniprot id: D6CUU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

426114:THI RS15535
gene id: 426114:THI_RS15535
uniprot id: D6CN33
names: Similarity
messages: Belongs to the P(II) protein family.

426114:THI RS08655
gene id: 426114:THI_RS08655
uniprot id: D6CTD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS02925
gene id: 426114:THI_RS02925
uniprot id: D6CRX7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

426114:THI RS07465
gene id: 426114:THI_RS07465
uniprot id: D6CSP5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

426114:THI RS03680
gene id: 426114:THI_RS03680
uniprot id: D6CKQ6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

426114:THI RS08230
gene id: 426114:THI_RS08230
uniprot id: D6CT51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS05385
gene id: 426114:THI_RS05385
uniprot id: D6CPE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

426114:THI RS06935
gene id: 426114:THI_RS06935
uniprot id: D6CQC7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

426114:THI RS08280
gene id: 426114:THI_RS08280
uniprot id: D6CT60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS11540
gene id: 426114:THI_RS11540
uniprot id: D6CV23
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

426114:THI RS04920
gene id: 426114:THI_RS04920
uniprot id: D6CL29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

426114:THI RS11315
gene id: 426114:THI_RS11315
uniprot id: D6CUX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

426114:THI RS05835
gene id: 426114:THI_RS05835
uniprot id: D6CPP0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

426114:THI RS13700
gene id: 426114:THI_RS13700
uniprot id: D6CLZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

426114:THI RS13935
gene id: 426114:THI_RS13935
uniprot id: D6CM48
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

426114:THI RS11510
gene id: 426114:THI_RS11510
uniprot id: D6CV17
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

426114:THI RS06440
gene id: 426114:THI_RS06440
uniprot id: D6CQ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

426114:THI RS08455
gene id: 426114:THI_RS08455
uniprot id: D6CT96
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

426114:THI RS09675
gene id: 426114:THI_RS09675
uniprot id: D6CTZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

426114:THI RS11325
gene id: 426114:THI_RS11325
uniprot id: D6CUX8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS12940
gene id: 426114:THI_RS12940
uniprot id: D6CLJ4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS10470
gene id: 426114:THI_RS10470
uniprot id: D6CUF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

426114:THI RS09920
gene id: 426114:THI_RS09920
uniprot id: D6CU48
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family.
messages: Part of the 50S ribosomal subunit.

426114:THI RS10265
gene id: 426114:THI_RS10265
uniprot id: D6CUB4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

426114:THI RS10040
gene id: 426114:THI_RS10040
uniprot id: D6CU72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

426114:THI RS01115
gene id: 426114:THI_RS01115
uniprot id: D6CQV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

426114:THI RS07795
gene id: 426114:THI_RS07795
uniprot id: D6CSW0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

426114:THI RS05300
gene id: 426114:THI_RS05300
uniprot id: D6CPC9
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

426114:THI RS08335
gene id: 426114:THI_RS08335
uniprot id: D6CT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

426114:THI RS09870
gene id: 426114:THI_RS09870
uniprot id: D6CU38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

426114:THI RS11775
gene id: 426114:THI_RS11775
uniprot id: D6CV72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

426114:THI RS03005
gene id: 426114:THI_RS03005
uniprot id: D6CRZ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

426114:THI RS16515
gene id: 426114:THI_RS16515
uniprot id: D6CNN9
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS01980
gene id: 426114:THI_RS01980
uniprot id: D6CRC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

426114:THI RS15570
gene id: 426114:THI_RS15570
uniprot id: D6CN40
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

426114:THI RS04080
gene id: 426114:THI_RS04080
uniprot id: D6CS76
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS01380
gene id: 426114:THI_RS01380
uniprot id: D6CR09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

426114:THI RS15015
gene id: 426114:THI_RS15015
uniprot id: D6CMS8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

426114:THI RS17410
gene id: 426114:THI_RS17410
uniprot id: D6CP74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

426114:THI RS00325
gene id: 426114:THI_RS00325
uniprot id: D6CVQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

426114:THI RS09700
gene id: 426114:THI_RS09700
uniprot id: D6CU04
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS04615
gene id: 426114:THI_RS04615
uniprot id: D6CKW7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

426114:THI RS01155
gene id: 426114:THI_RS01155
uniprot id: D6CQW0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

426114:THI RS14805
gene id: 426114:THI_RS14805
uniprot id: D6CMN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS03355
gene id: 426114:THI_RS03355
uniprot id: D6CKI9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

426114:THI RS16745
gene id: 426114:THI_RS16745
uniprot id: D6CNU0
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS07555
gene id: 426114:THI_RS07555
uniprot id: D6CSR4
names: Subcellular Location Annotation
messages: Cytoplasm

426114:THI RS08040
gene id: 426114:THI_RS08040
uniprot id: D6CT12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

426114:THI RS15765
gene id: 426114:THI_RS15765
uniprot id: D6CN81
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

426114:THI RS06355
gene id: 426114:THI_RS06355
uniprot id: D6CPZ8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

426114:THI RS12045
gene id: 426114:THI_RS12045
uniprot id: D6CVC6
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS00290
gene id: 426114:THI_RS00290
uniprot id: D6CVP4
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS16320
gene id: 426114:THI_RS16320
uniprot id: D6CNJ6
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS04700
gene id: 426114:THI_RS04700
uniprot id: D6CKY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

426114:THI RS11310
gene id: 426114:THI_RS11310
uniprot id: D6CUX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

426114:THI RS02580
gene id: 426114:THI_RS02580
uniprot id: D6CRQ2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

426114:THI RS06020
gene id: 426114:THI_RS06020
uniprot id: D6CPT1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS05120
gene id: 426114:THI_RS05120
uniprot id: D6CL71
names: Similarity
messages: Belongs to the oxoprolinase family.

426114:THI RS16415
gene id: 426114:THI_RS16415
uniprot id: D6CNL5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

426114:THI RS15870
gene id: 426114:THI_RS15870
uniprot id: D6CNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

426114:THI RS08135
gene id: 426114:THI_RS08135
uniprot id: D6CT31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

426114:THI RS09810
gene id: 426114:THI_RS09810
uniprot id: D6CU26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

426114:THI RS07540
gene id: 426114:THI_RS07540
uniprot id: D6CSR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

426114:THI RS09615
gene id: 426114:THI_RS09615
uniprot id: D6CTY7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

426114:THI RS11250
gene id: 426114:THI_RS11250
uniprot id: D6CUW3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

426114:THI RS13220
gene id: 426114:THI_RS13220
uniprot id: D6CLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

426114:THI RS10990
gene id: 426114:THI_RS10990
uniprot id: D6CUR0
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS09540
gene id: 426114:THI_RS09540
uniprot id: D6CTX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

426114:THI RS01990
gene id: 426114:THI_RS01990
uniprot id: D6CRC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

426114:THI RS11880
gene id: 426114:THI_RS11880
uniprot id: D6CV93
names: Similarity
messages: Belongs to the peptidase M20 family.

426114:THI RS08100
gene id: 426114:THI_RS08100
uniprot id: D6CT24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

426114:THI RS12730
gene id: 426114:THI_RS12730
uniprot id: D6CLF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

426114:THI RS17020
gene id: 426114:THI_RS17020
uniprot id: D6CP00
names: Subcellular Location Annotation
messages: Periplasm

426114:THI RS07460
gene id: 426114:THI_RS07460
uniprot id: D6CSP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

426114:THI RS13150
gene id: 426114:THI_RS13150
uniprot id: D6CLN7
names: Subcellular Location Annotation
messages: Cytoplasm

426114:THI RS12330
gene id: 426114:THI_RS12330
uniprot id: D6CVI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

426114:THI RS01740
gene id: 426114:THI_RS01740
uniprot id: D6CR80
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

426114:THI RS12135
gene id: 426114:THI_RS12135
uniprot id: D6CVE4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

426114:THI RS01835
gene id: 426114:THI_RS01835
uniprot id: D6CR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

426114:THI RS12935
gene id: 426114:THI_RS12935
uniprot id: D6CLJ3
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS00440
gene id: 426114:THI_RS00440
uniprot id: D6CKE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS16710
gene id: 426114:THI_RS16710
uniprot id: D6CNT1
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

426114:THI RS13465
gene id: 426114:THI_RS13465
uniprot id: D6CLV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

426114:THI RS03900
gene id: 426114:THI_RS03900
uniprot id: D6CKU9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

426114:THI RS02080
gene id: 426114:THI_RS02080
uniprot id: D6CRE7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

426114:THI RS10675
gene id: 426114:THI_RS10675
uniprot id: D6CPQ7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

426114:THI RS07020
gene id: 426114:THI_RS07020
uniprot id: D6CQE4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

426114:THI RS12085
gene id: 426114:THI_RS12085
uniprot id: D6CVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

426114:THI RS05590
gene id: 426114:THI_RS05590
uniprot id: D6CPI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

426114:THI RS07185
gene id: 426114:THI_RS07185
uniprot id: D6CSI9
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS13980
gene id: 426114:THI_RS13980
uniprot id: D6CM58
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

426114:THI RS02685
gene id: 426114:THI_RS02685
uniprot id: D6CRS3
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS05355
gene id: 426114:THI_RS05355
uniprot id: D6CPE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

426114:THI RS09875
gene id: 426114:THI_RS09875
uniprot id: D6CU39
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

426114:THI RS12370
gene id: 426114:THI_RS12370
uniprot id: D6CVJ0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

426114:THI RS04590
gene id: 426114:THI_RS04590
uniprot id: D6CKW2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

426114:THI RS14695
gene id: 426114:THI_RS14695
uniprot id: D6CMK9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

426114:THI RS10735
gene id: 426114:THI_RS10735
uniprot id: D6CUK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

426114:THI RS11705
gene id: 426114:THI_RS11705
uniprot id: D6CV58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS09595
gene id: 426114:THI_RS09595
uniprot id: D6CTY3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

426114:THI RS06075
gene id: 426114:THI_RS06075
uniprot id: D6CPU2
names: Similarity
messages: Belongs to the SCO1/2 family.

426114:THI RS09185
gene id: 426114:THI_RS09185
uniprot id: D6CTP7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

426114:THI RS01305
gene id: 426114:THI_RS01305
uniprot id: D6CQZ2
names: Similarity
messages: Belongs to the GbsR family.

426114:THI RS13210
gene id: 426114:THI_RS13210
uniprot id: D6CLQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

426114:THI RS05135
gene id: 426114:THI_RS05135
uniprot id: D6CL74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

426114:THI RS01705
gene id: 426114:THI_RS01705
uniprot id: D6CR73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

426114:THI RS03185
gene id: 426114:THI_RS03185
uniprot id: D6CS29
names: Subcellular Location Annotation
messages: Periplasm

426114:THI RS12930
gene id: 426114:THI_RS12930
uniprot id: D6CLJ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

426114:THI RS03030
gene id: 426114:THI_RS03030
uniprot id: D6CRZ9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

426114:THI RS05115
gene id: 426114:THI_RS05115
uniprot id: D6CL70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

426114:THI RS07360
gene id: 426114:THI_RS07360
uniprot id: D6CSM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

426114:THI RS12335
gene id: 426114:THI_RS12335
uniprot id: D6CVI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

426114:THI RS03375
gene id: 426114:THI_RS03375
uniprot id: D6CKJ4
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

426114:THI RS13525
gene id: 426114:THI_RS13525
uniprot id: D6CLW4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS14370
gene id: 426114:THI_RS14370
uniprot id: D6CME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

426114:THI RS05920
gene id: 426114:THI_RS05920
uniprot id: D6CPQ7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

426114:THI RS08670
gene id: 426114:THI_RS08670
uniprot id: D6CTE0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

426114:THI RS15865
gene id: 426114:THI_RS15865
uniprot id: D6CNA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

426114:THI RS00835
gene id: 426114:THI_RS00835
uniprot id: D6CQP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

426114:THI RS06910
gene id: 426114:THI_RS06910
uniprot id: D6CQC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

426114:THI RS01890
gene id: 426114:THI_RS01890
uniprot id: D6CRB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

426114:THI RS15610
gene id: 426114:THI_RS15610
uniprot id: D6CN48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS11950
gene id: 426114:THI_RS11950
uniprot id: D6CVA7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

426114:THI RS09490
gene id: 426114:THI_RS09490
uniprot id: D6CTW3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

426114:THI RS12340
gene id: 426114:THI_RS12340
uniprot id: A0A8I1MV23
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS12615
gene id: 426114:THI_RS12615
uniprot id: D6CLC9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

426114:THI RS08095
gene id: 426114:THI_RS08095
uniprot id: D6CT23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS02280
gene id: 426114:THI_RS02280
uniprot id: D6CRI8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

426114:THI RS00930
gene id: 426114:THI_RS00930
uniprot id: D6CQR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

426114:THI RS01815
gene id: 426114:THI_RS01815
uniprot id: D6CR94
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

426114:THI RS03060
gene id: 426114:THI_RS03060
uniprot id: D6CS05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS04295
gene id: 426114:THI_RS04295
uniprot id: D6CSC7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

426114:THI RS10410
gene id: 426114:THI_RS10410
uniprot id: D6CUE2
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

426114:THI RS16400
gene id: 426114:THI_RS16400
uniprot id: D6CNL2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

426114:THI RS00105
gene id: 426114:THI_RS00105
uniprot id: D6CKH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

426114:THI RS10165
gene id: 426114:THI_RS10165
uniprot id: D6CU97
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS12155
gene id: 426114:THI_RS12155
uniprot id: D6CVE8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

426114:THI RS16595
gene id: 426114:THI_RS16595
uniprot id: D6CNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS11405
gene id: 426114:THI_RS11405
uniprot id: D6CUZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

426114:THI RS02545
gene id: 426114:THI_RS02545
uniprot id: D6CRP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

426114:THI RS11370
gene id: 426114:THI_RS11370
uniprot id: D6CUY7
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS00535
gene id: 426114:THI_RS00535
uniprot id: D6CQI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

426114:THI RS14665
gene id: 426114:THI_RS14665
uniprot id: D6CMK4
names: Similarity
messages: Belongs to the asparagine synthetase family.

426114:THI RS14865
gene id: 426114:THI_RS14865
uniprot id: D6CMP8
names: Similarity
messages: Belongs to the peptidase S13 family.

426114:THI RS12420
gene id: 426114:THI_RS12420
uniprot id: D6CVK0
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

426114:THI RS10150
gene id: 426114:THI_RS10150
uniprot id: D6CU94
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

426114:THI RS04055
gene id: 426114:THI_RS04055
uniprot id: D6CS70
names: Similarity
messages: Belongs to the UPF0145 family.

426114:THI RS13780
gene id: 426114:THI_RS13780
uniprot id: D6CM15
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

426114:THI RS05725
gene id: 426114:THI_RS05725
uniprot id: D6CPL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

426114:THI RS11720
gene id: 426114:THI_RS11720
uniprot id: D6CV61
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS04445
gene id: 426114:THI_RS04445
uniprot id: D6CSF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

426114:THI RS13080
gene id: 426114:THI_RS13080
uniprot id: D6CLM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

426114:THI RS15435
gene id: 426114:THI_RS15435
uniprot id: D6CN12
names: Similarity
messages: Belongs to the malate synthase family.

426114:THI RS06380
gene id: 426114:THI_RS06380
uniprot id: D6CQ03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

426114:THI RS15075
gene id: 426114:THI_RS15075
uniprot id: D6CMU0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

426114:THI RS01830
gene id: 426114:THI_RS01830
uniprot id: D6CR97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

426114:THI RS12805
gene id: 426114:THI_RS12805
uniprot id: D6CLG7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

426114:THI RS12890
gene id: 426114:THI_RS12890
uniprot id: D6CLI4
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS07675
gene id: 426114:THI_RS07675
uniprot id: D6CST7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

426114:THI RS04525
gene id: 426114:THI_RS04525
uniprot id: D6CSH4
names: Subcellular Location Annotation
messages: Periplasm

426114:THI RS05820
gene id: 426114:THI_RS05820
uniprot id: D6CPN7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

426114:THI RS05745
gene id: 426114:THI_RS05745
uniprot id: D6CPM2
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

426114:THI RS09865
gene id: 426114:THI_RS09865
uniprot id: D6CU37
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

426114:THI RS02910
gene id: 426114:THI_RS02910
uniprot id: D6CRX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

426114:THI RS00650
gene id: 426114:THI_RS00650
uniprot id: D6CQK9
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

426114:THI RS13925
gene id: 426114:THI_RS13925
uniprot id: D6CM46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

426114:THI RS09695
gene id: 426114:THI_RS09695
uniprot id: D6CU03
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS01285
gene id: 426114:THI_RS01285
uniprot id: D6CQY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

426114:THI RS10130
gene id: 426114:THI_RS10130
uniprot id: D6CU90
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

426114:THI RS10640
gene id: 426114:THI_RS10640
uniprot id: D6CUI6
names: Similarity
messages: Belongs to the type IA topoisomerase family.

426114:THI RS08890
gene id: 426114:THI_RS08890
uniprot id: D6CTI4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

426114:THI RS09600
gene id: 426114:THI_RS09600
uniprot id: D6CTY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

426114:THI RS10320
gene id: 426114:THI_RS10320
uniprot id: D6CUC5
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS08130
gene id: 426114:THI_RS08130
uniprot id: D6CT30
names: Similarity
messages: Belongs to the pirin family.

426114:THI RS15280
gene id: 426114:THI_RS15280
uniprot id: D6CMY1
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

426114:THI RS00640
gene id: 426114:THI_RS00640
uniprot id: D6CQK7
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

426114:THI RS12065
gene id: 426114:THI_RS12065
uniprot id: D6CVD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

426114:THI RS03120
gene id: 426114:THI_RS03120
uniprot id: D6CS17
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS03970
gene id: 426114:THI_RS03970
uniprot id: D6CS53
names: Similarity
messages: Belongs to the GST superfamily.

426114:THI RS16830
gene id: 426114:THI_RS16830
uniprot id: D6CNV8
names: Similarity
messages: Belongs to the creatininase superfamily.

426114:THI RS01575
gene id: 426114:THI_RS01575
uniprot id: D6CR47
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

426114:THI RS15850
gene id: 426114:THI_RS15850
uniprot id: D6CN98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

426114:THI RS01845
gene id: 426114:THI_RS01845
uniprot id: D6CRA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

426114:THI RS00770
gene id: 426114:THI_RS00770
uniprot id: D6CQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

426114:THI RS06445
gene id: 426114:THI_RS06445
uniprot id: D6CQ17
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

426114:THI RS10595
gene id: 426114:THI_RS10595
uniprot id: D6CUH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS04125
gene id: 426114:THI_RS04125
uniprot id: D6CS86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS17265
gene id: 426114:THI_RS17265
uniprot id: D6CP45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS04360
gene id: 426114:THI_RS04360
uniprot id: D6CSE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS16325
gene id: 426114:THI_RS16325
uniprot id: D6CNJ7
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS01200
gene id: 426114:THI_RS01200
uniprot id: D6CQX0
names: PTM
messages: Binds 1 heme c group covalently per subunit.

426114:THI RS05505
gene id: 426114:THI_RS05505
uniprot id: D6CPH0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS13940
gene id: 426114:THI_RS13940
uniprot id: A0A8I1MWF7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

426114:THI RS04735
gene id: 426114:THI_RS04735
uniprot id: D6CKZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

426114:THI RS01720
gene id: 426114:THI_RS01720
uniprot id: D6CR76
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

426114:THI RS14030
gene id: 426114:THI_RS14030
uniprot id: D6CM68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

426114:THI RS06825
gene id: 426114:THI_RS06825
uniprot id: D6CQA6
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

426114:THI RS06500
gene id: 426114:THI_RS06500
uniprot id: D6CQ29
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

426114:THI RS00710
gene id: 426114:THI_RS00710
uniprot id: D6CQM1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS07365
gene id: 426114:THI_RS07365
uniprot id: D6CSM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

426114:THI RS12810
gene id: 426114:THI_RS12810
uniprot id: D6CLG8
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

426114:THI RS03490
gene id: 426114:THI_RS03490
uniprot id: D6CKL8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

426114:THI RS05905
gene id: 426114:THI_RS05905
uniprot id: D6CPQ4
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS09640
gene id: 426114:THI_RS09640
uniprot id: D6CTZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS04685
gene id: 426114:THI_RS04685
uniprot id: D6CKY1
names: Similarity
messages: Belongs to the thioredoxin family.

426114:THI RS11065
gene id: 426114:THI_RS11065
uniprot id: D6CUS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS02370
gene id: 426114:THI_RS02370
uniprot id: D6CPQ8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS12070
gene id: 426114:THI_RS12070
uniprot id: D6CVD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

426114:THI RS12060
gene id: 426114:THI_RS12060
uniprot id: D6CVC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

426114:THI RS14705
gene id: 426114:THI_RS14705
uniprot id: D6CML1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

426114:THI RS00430
gene id: 426114:THI_RS00430
uniprot id: D6CKE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

426114:THI RS13985
gene id: 426114:THI_RS13985
uniprot id: D6CM59
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

426114:THI RS10520
gene id: 426114:THI_RS10520
uniprot id: D6CUG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

426114:THI RS17465
gene id: 426114:THI_RS17465
uniprot id: D6CP86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

426114:THI RS00940
gene id: 426114:THI_RS00940
uniprot id: D6CQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS12345
gene id: 426114:THI_RS12345
uniprot id: D6CVI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

426114:THI RS10445
gene id: 426114:THI_RS10445
uniprot id: D6CUE9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

426114:THI RS05335
gene id: 426114:THI_RS05335
uniprot id: D6CPD6
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS05090
gene id: 426114:THI_RS05090
uniprot id: D6CL64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

426114:THI RS15220
gene id: 426114:THI_RS15220
uniprot id: D6CMW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

426114:THI RS13945
gene id: 426114:THI_RS13945
uniprot id: D6CM50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

426114:THI RS00415
gene id: 426114:THI_RS00415
uniprot id: D6CKD8
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS04730
gene id: 426114:THI_RS04730
uniprot id: D6CKZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

426114:THI RS01965
gene id: 426114:THI_RS01965
uniprot id: D6CRC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

426114:THI RS12720
gene id: 426114:THI_RS12720
uniprot id: D6CLF0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

426114:THI RS15775
gene id: 426114:THI_RS15775
uniprot id: D6CN83
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

426114:THI RS11730
gene id: 426114:THI_RS11730
uniprot id: D6CV63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

426114:THI RS17115
gene id: 426114:THI_RS17115
uniprot id: D6CP19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

426114:THI RS11265
gene id: 426114:THI_RS11265
uniprot id: D6CUW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

426114:THI RS02815
gene id: 426114:THI_RS02815
uniprot id: D6CNX9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

426114:THI RS06550
gene id: 426114:THI_RS06550
uniprot id: D6CPQ8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS01270
gene id: 426114:THI_RS01270
uniprot id: D6CQY4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

426114:THI RS01175
gene id: 426114:THI_RS01175
uniprot id: D6CQW4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

426114:THI RS15190
gene id: 426114:THI_RS15190
uniprot id: D6CMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

426114:THI RS00615
gene id: 426114:THI_RS00615
uniprot id: D6CQK2
names: Similarity
messages: Belongs to the CsoS2 family.

426114:THI RS04095
gene id: 426114:THI_RS04095
uniprot id: D6CS79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

426114:THI RS16920
gene id: 426114:THI_RS16920
uniprot id: D6CNX9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

426114:THI RS04810
gene id: 426114:THI_RS04810
uniprot id: D6CL06
names: Similarity
messages: Belongs to the ABC transporter superfamily.

426114:THI RS08465
gene id: 426114:THI_RS08465
uniprot id: D6CT98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

426114:THI RS00335
gene id: 426114:THI_RS00335
uniprot id: D6CVQ4
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS11335
gene id: 426114:THI_RS11335
uniprot id: D6CUY0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

426114:THI RS00190
gene id: 426114:THI_RS00190
uniprot id: D6CVM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

426114:THI RS12285
gene id: 426114:THI_RS12285
uniprot id: D6CVH4
names: Similarity
messages: Belongs to the peptidase C40 family.

426114:THI RS09650
gene id: 426114:THI_RS09650
uniprot id: D6CTZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

426114:THI RS04720
gene id: 426114:THI_RS04720
uniprot id: D6CKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

426114:THI RS12405
gene id: 426114:THI_RS12405
uniprot id: D6CVJ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS13690
gene id: 426114:THI_RS13690
uniprot id: D6CLZ6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

426114:THI RS04800
gene id: 426114:THI_RS04800
uniprot id: D6CL04
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

426114:THI RS00765
gene id: 426114:THI_RS00765
uniprot id: D6CQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

426114:THI RS01975
gene id: 426114:THI_RS01975
uniprot id: D6CRC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

426114:THI RS00910
gene id: 426114:THI_RS00910
uniprot id: D6CQR1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

426114:THI RS11285
gene id: 426114:THI_RS11285
uniprot id: D6CUX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

426114:THI RS17880
gene id: 426114:THI_RS17880
uniprot id: D6CVV9
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS13695
gene id: 426114:THI_RS13695
uniprot id: D6CLZ7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

426114:THI RS09145
gene id: 426114:THI_RS09145
uniprot id: D6CTN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

426114:THI RS04450
gene id: 426114:THI_RS04450
uniprot id: D6CSF8
names: Subcellular Location Annotation
messages: Periplasm

426114:THI RS00265
gene id: 426114:THI_RS00265
uniprot id: D6CVN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

426114:THI RS08625
gene id: 426114:THI_RS08625
uniprot id: D6CTD1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

426114:THI RS15805
gene id: 426114:THI_RS15805
uniprot id: D6CN89
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

426114:THI RS13575
gene id: 426114:THI_RS13575
uniprot id: D6CLX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

426114:THI RS15520
gene id: 426114:THI_RS15520
uniprot id: D6CN30
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

426114:THI RS01310
gene id: 426114:THI_RS01310
uniprot id: D6CQZ3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

426114:THI RS13750
gene id: 426114:THI_RS13750
uniprot id: D6CM09
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

426114:THI RS02590
gene id: 426114:THI_RS02590
uniprot id: D6CRQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

426114:THI RS03045
gene id: 426114:THI_RS03045
uniprot id: D6CS02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

426114:THI RS09885
gene id: 426114:THI_RS09885
uniprot id: D6CU41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

426114:THI RS01050
gene id: 426114:THI_RS01050
uniprot id: D6CQT9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

426114:THI RS16495
gene id: 426114:THI_RS16495
uniprot id: D6CNN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

426114:THI RS11440
gene id: 426114:THI_RS11440
uniprot id: D6CV01
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS08115
gene id: 426114:THI_RS08115
uniprot id: D6CT27
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS17620
gene id: 426114:THI_RS17620
uniprot id: D6CPB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

426114:THI RS14905
gene id: 426114:THI_RS14905
uniprot id: D6CMQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

426114:THI RS05350
gene id: 426114:THI_RS05350
uniprot id: D6CPD9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

426114:THI RS15835
gene id: 426114:THI_RS15835
uniprot id: D6CN95
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

426114:THI RS09820
gene id: 426114:THI_RS09820
uniprot id: D6CU28
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

426114:THI RS08740
gene id: 426114:THI_RS08740
uniprot id: D6CTF4
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS06185
gene id: 426114:THI_RS06185
uniprot id: D6CPW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

426114:THI RS00870
gene id: 426114:THI_RS00870
uniprot id: D6CQQ3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

426114:THI RS07785
gene id: 426114:THI_RS07785
uniprot id: D6CSV8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

426114:THI RS06375
gene id: 426114:THI_RS06375
uniprot id: D6CQ02
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

426114:THI RS13725
gene id: 426114:THI_RS13725
uniprot id: D6CM04
names: PTM
messages: Binds 1 heme c group covalently per subunit.

426114:THI RS00465
gene id: 426114:THI_RS00465
uniprot id: D6CKE9
names: Similarity
messages: Belongs to the DprA/Smf family.

426114:THI RS13620
gene id: 426114:THI_RS13620
uniprot id: D6CLY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

426114:THI RS00100
gene id: 426114:THI_RS00100
uniprot id: D6CKH2
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

426114:THI RS00580
gene id: 426114:THI_RS00580
uniprot id: D6CQJ4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

426114:THI RS01940
gene id: 426114:THI_RS01940
uniprot id: D6CRC0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

426114:THI RS00405
gene id: 426114:THI_RS00405
uniprot id: D6CKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

426114:THI RS09705
gene id: 426114:THI_RS09705
uniprot id: D6CU05
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS00015
gene id: 426114:THI_RS00015
uniprot id: D6CKF5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

426114:THI RS12980
gene id: 426114:THI_RS12980
uniprot id: D6CLK2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

426114:THI RS11520
gene id: 426114:THI_RS11520
uniprot id: D6CV19
names: Similarity
messages: Belongs to the OprB family.

426114:THI RS07140
gene id: 426114:THI_RS07140
uniprot id: D6CQG9
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

426114:THI RS16425
gene id: 426114:THI_RS16425
uniprot id: D6CNL7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

426114:THI RS07600
gene id: 426114:THI_RS07600
uniprot id: D6CSS3
names: Similarity
messages: Belongs to the UPF0234 family.

426114:THI RS14435
gene id: 426114:THI_RS14435
uniprot id: D6CMF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

426114:THI RS11475
gene id: 426114:THI_RS11475
uniprot id: D6CV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS06950
gene id: 426114:THI_RS06950
uniprot id: D6CQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

426114:THI RS00810
gene id: 426114:THI_RS00810
uniprot id: D6CQP1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

426114:THI RS01645
gene id: 426114:THI_RS01645
uniprot id: D6CR61
names: Function
names: Similarity
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.

426114:THI RS15100
gene id: 426114:THI_RS15100
uniprot id: D6CMU5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

426114:THI RS02900
gene id: 426114:THI_RS02900
uniprot id: D6CRX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

426114:THI RS03450
gene id: 426114:THI_RS03450
uniprot id: D6CKK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

426114:THI RS11320
gene id: 426114:THI_RS11320
uniprot id: D6CUX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

426114:THI RS06040
gene id: 426114:THI_RS06040
uniprot id: A0A8I1MU94
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS00695
gene id: 426114:THI_RS00695
uniprot id: D6CQL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

426114:THI RS10475
gene id: 426114:THI_RS10475
uniprot id: D6CUF5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

426114:THI RS17100
gene id: 426114:THI_RS17100
uniprot id: D6CP16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

426114:THI RS18915
gene id: 426114:THI_RS18915
uniprot id: D6CL99
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

426114:THI RS14135
gene id: 426114:THI_RS14135
uniprot id: D6CM92
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS17485
gene id: 426114:THI_RS17485
uniprot id: D6CP90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

426114:THI RS17355
gene id: 426114:THI_RS17355
uniprot id: D6CP63
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

426114:THI RS13865
gene id: 426114:THI_RS13865
uniprot id: D6CM33
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

426114:THI RS08070
gene id: 426114:THI_RS08070
uniprot id: D6CT18
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS04715
gene id: 426114:THI_RS04715
uniprot id: D6CKY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

426114:THI RS07670
gene id: 426114:THI_RS07670
uniprot id: D6CST6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

426114:THI RS04895
gene id: 426114:THI_RS04895
uniprot id: D6CL24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS03525
gene id: 426114:THI_RS03525
uniprot id: D6CKM5
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

426114:THI RS08185
gene id: 426114:THI_RS08185
uniprot id: D6CT42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

426114:THI RS06055
gene id: 426114:THI_RS06055
uniprot id: D6CPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

426114:THI RS10020
gene id: 426114:THI_RS10020
uniprot id: D6CU68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

426114:THI RS06410
gene id: 426114:THI_RS06410
uniprot id: D6CQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

426114:THI RS02035
gene id: 426114:THI_RS02035
uniprot id: D6CRD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

426114:THI RS11225
gene id: 426114:THI_RS11225
uniprot id: D6CUV8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

426114:THI RS12645
gene id: 426114:THI_RS12645
uniprot id: D6CLD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

426114:THI RS08315
gene id: 426114:THI_RS08315
uniprot id: D6CT68
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

426114:THI RS08200
gene id: 426114:THI_RS08200
uniprot id: D6CT45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

426114:THI RS15285
gene id: 426114:THI_RS15285
uniprot id: D6CMY2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

426114:THI RS14235
gene id: 426114:THI_RS14235
uniprot id: D6CMB5
names: Subcellular Location Annotation
messages: Periplasm

426114:THI RS15265
gene id: 426114:THI_RS15265
uniprot id: D6CMX8
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS04885
gene id: 426114:THI_RS04885
uniprot id: D6CL22
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS13010
gene id: 426114:THI_RS13010
uniprot id: D6CLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

426114:THI RS07485
gene id: 426114:THI_RS07485
uniprot id: D6CSP9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

426114:THI RS00280
gene id: 426114:THI_RS00280
uniprot id: D6CVP1
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

426114:THI RS00545
gene id: 426114:THI_RS00545
uniprot id: D6CQI7
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

426114:THI RS02970
gene id: 426114:THI_RS02970
uniprot id: D6CRY6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

426114:THI RS03445
gene id: 426114:THI_RS03445
uniprot id: D6CKK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

426114:THI RS03305
gene id: 426114:THI_RS03305
uniprot id: D6CKH9
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS00875
gene id: 426114:THI_RS00875
uniprot id: D6CQQ4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

426114:THI RS07970
gene id: 426114:THI_RS07970
uniprot id: D6CSZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

426114:THI RS07960
gene id: 426114:THI_RS07960
uniprot id: D6CSZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

426114:THI RS10280
gene id: 426114:THI_RS10280
uniprot id: D6CUB7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

426114:THI RS06345
gene id: 426114:THI_RS06345
uniprot id: D6CPZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

426114:THI RS02705
gene id: 426114:THI_RS02705
uniprot id: D6CRS7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

426114:THI RS01300
gene id: 426114:THI_RS01300
uniprot id: D6CQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS05890
gene id: 426114:THI_RS05890
uniprot id: D6CPQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

426114:THI RS04785
gene id: 426114:THI_RS04785
uniprot id: D6CL01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

426114:THI RS04395
gene id: 426114:THI_RS04395
uniprot id: D6CSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

426114:THI RS12110
gene id: 426114:THI_RS12110
uniprot id: D6CVD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

426114:THI RS17170
gene id: 426114:THI_RS17170
uniprot id: D6CP26
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS07375
gene id: 426114:THI_RS07375
uniprot id: D6CSM7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

426114:THI RS18230
gene id: 426114:THI_RS18230
uniprot id: D6CVV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

426114:THI RS07990
gene id: 426114:THI_RS07990
uniprot id: D6CT02
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS06145
gene id: 426114:THI_RS06145
uniprot id: D6CPV7
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

426114:THI RS07545
gene id: 426114:THI_RS07545
uniprot id: D6CSR1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

426114:THI RS17725
gene id: 426114:THI_RS17725
uniprot id: D6CVS1
names: Similarity
messages: Belongs to the transposase 7 family.

426114:THI RS11635
gene id: 426114:THI_RS11635
uniprot id: D6CPR5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS04870
gene id: 426114:THI_RS04870
uniprot id: D6CL19
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

426114:THI RS06090
gene id: 426114:THI_RS06090
uniprot id: D6CPU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

426114:THI RS08705
gene id: 426114:THI_RS08705
uniprot id: D6CTE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

426114:THI RS00890
gene id: 426114:THI_RS00890
uniprot id: D6CQQ7
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS08585
gene id: 426114:THI_RS08585
uniprot id: D6CTC3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

426114:THI RS11690
gene id: 426114:THI_RS11690
uniprot id: D6CV55
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

426114:THI RS10585
gene id: 426114:THI_RS10585
uniprot id: D6CUH7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

426114:THI RS11770
gene id: 426114:THI_RS11770
uniprot id: D6CV71
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

426114:THI RS07345
gene id: 426114:THI_RS07345
uniprot id: D6CSM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

426114:THI RS08550
gene id: 426114:THI_RS08550
uniprot id: D6CTB6
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

426114:THI RS15820
gene id: 426114:THI_RS15820
uniprot id: D6CN92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

426114:THI RS11700
gene id: 426114:THI_RS11700
uniprot id: D6CV57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

426114:THI RS02655
gene id: 426114:THI_RS02655
uniprot id: D6CRR7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

426114:THI RS02905
gene id: 426114:THI_RS02905
uniprot id: D6CRX3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

426114:THI RS11415
gene id: 426114:THI_RS11415
uniprot id: D6CUZ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

426114:THI RS01955
gene id: 426114:THI_RS01955
uniprot id: D6CRC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

426114:THI RS17505
gene id: 426114:THI_RS17505
uniprot id: D6CP94
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

426114:THI RS14680
gene id: 426114:THI_RS14680
uniprot id: D6CMK7
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS05405
gene id: 426114:THI_RS05405
uniprot id: D6CPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

426114:THI RS17470
gene id: 426114:THI_RS17470
uniprot id: D6CP87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

426114:THI RS11000
gene id: 426114:THI_RS11000
uniprot id: D6CUR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

426114:THI RS05205
gene id: 426114:THI_RS05205
uniprot id: D6CL88
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

426114:THI RS15010
gene id: 426114:THI_RS15010
uniprot id: D6CMS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

426114:THI RS05105
gene id: 426114:THI_RS05105
uniprot id: D6CL67
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

426114:THI RS11005
gene id: 426114:THI_RS11005
uniprot id: D6CUR4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

426114:THI RS13215
gene id: 426114:THI_RS13215
uniprot id: D6CLQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

426114:THI RS08925
gene id: 426114:THI_RS08925
uniprot id: D6CTJ1
names: Similarity
messages: Belongs to the VapB family.

426114:THI RS00450
gene id: 426114:THI_RS00450
uniprot id: D6CKE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

426114:THI RS14520
gene id: 426114:THI_RS14520
uniprot id: D6CMH5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

426114:THI RS11545
gene id: 426114:THI_RS11545
uniprot id: D6CV24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

426114:THI RS01765
gene id: 426114:THI_RS01765
uniprot id: D6CR85
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

426114:THI RS03805
gene id: 426114:THI_RS03805
uniprot id: D6CKS9
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS07640
gene id: 426114:THI_RS07640
uniprot id: D6CST0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

426114:THI RS00830
gene id: 426114:THI_RS00830
uniprot id: D6CQP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

426114:THI RS05085
gene id: 426114:THI_RS05085
uniprot id: D6CL63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

426114:THI RS08005
gene id: 426114:THI_RS08005
uniprot id: D6CT05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS16190
gene id: 426114:THI_RS16190
uniprot id: D6CNG8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

426114:THI RS10865
gene id: 426114:THI_RS10865
uniprot id: D6CPQ7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

426114:THI RS09340
gene id: 426114:THI_RS09340
uniprot id: D6CTS9
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

426114:THI RS05130
gene id: 426114:THI_RS05130
uniprot id: D6CL73
names: Similarity
messages: Belongs to the GARS family.

426114:THI RS13730
gene id: 426114:THI_RS13730
uniprot id: D6CM05
names: Similarity
messages: Belongs to the leucine-binding protein family.

426114:THI RS04690
gene id: 426114:THI_RS04690
uniprot id: D6CKY2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

426114:THI RS07630
gene id: 426114:THI_RS07630
uniprot id: D6CSS8
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

426114:THI RS15790
gene id: 426114:THI_RS15790
uniprot id: D6CN86
names: Similarity
messages: Belongs to the OprB family.

426114:THI RS00350
gene id: 426114:THI_RS00350
uniprot id: D6CPQ8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS12695
gene id: 426114:THI_RS12695
uniprot id: D6CLE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

426114:THI RS11850
gene id: 426114:THI_RS11850
uniprot id: D6CV87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

426114:THI RS11215
gene id: 426114:THI_RS11215
uniprot id: D6CUV6
names: Similarity
messages: Belongs to the PhoH family.

426114:THI RS09300
gene id: 426114:THI_RS09300
uniprot id: D6CTS1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS14420
gene id: 426114:THI_RS14420
uniprot id: D6CMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

426114:THI RS10795
gene id: 426114:THI_RS10795
uniprot id: D6CUL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

426114:THI RS14700
gene id: 426114:THI_RS14700
uniprot id: D6CML0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

426114:THI RS12775
gene id: 426114:THI_RS12775
uniprot id: D6CLG1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

426114:THI RS05050
gene id: 426114:THI_RS05050
uniprot id: D6CL56
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

426114:THI RS15065
gene id: 426114:THI_RS15065
uniprot id: D6CMT8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

426114:THI RS07330
gene id: 426114:THI_RS07330
uniprot id: D6CSL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

426114:THI RS10205
gene id: 426114:THI_RS10205
uniprot id: D6CUA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

426114:THI RS12375
gene id: 426114:THI_RS12375
uniprot id: D6CVJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

426114:THI RS19485
gene id: 426114:THI_RS19485
uniprot id: D6CPJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

426114:THI RS12450
gene id: 426114:THI_RS12450
uniprot id: D6CVK6
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

426114:THI RS07025
gene id: 426114:THI_RS07025
uniprot id: D6CQE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

426114:THI RS04415
gene id: 426114:THI_RS04415
uniprot id: D6CSF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

426114:THI RS12390
gene id: 426114:THI_RS12390
uniprot id: D6CVJ4
names: Similarity
messages: Belongs to the TrpF family.

426114:THI RS13880
gene id: 426114:THI_RS13880
uniprot id: D6CM36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

426114:THI RS14965
gene id: 426114:THI_RS14965
uniprot id: D6CMR8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

426114:THI RS13810
gene id: 426114:THI_RS13810
uniprot id: D6CM22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

426114:THI RS05730
gene id: 426114:THI_RS05730
uniprot id: D6CPL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

426114:THI RS02005
gene id: 426114:THI_RS02005
uniprot id: D6CRD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

426114:THI RS13180
gene id: 426114:THI_RS13180
uniprot id: D6CLP3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

426114:THI RS00040
gene id: 426114:THI_RS00040
uniprot id: D6CKG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

426114:THI RS13970
gene id: 426114:THI_RS13970
uniprot id: D6CM55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

426114:THI RS00130
gene id: 426114:THI_RS00130
uniprot id: D6CVK7
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS12055
gene id: 426114:THI_RS12055
uniprot id: D6CVC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

426114:THI RS02015
gene id: 426114:THI_RS02015
uniprot id: D6CRD4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

426114:THI RS07065
gene id: 426114:THI_RS07065
uniprot id: D6CQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

426114:THI RS09200
gene id: 426114:THI_RS09200
uniprot id: D6CTQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

426114:THI RS12630
gene id: 426114:THI_RS12630
uniprot id: D6CLD2
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

426114:THI RS11835
gene id: 426114:THI_RS11835
uniprot id: D6CV84
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

426114:THI RS12705
gene id: 426114:THI_RS12705
uniprot id: D6CLE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

426114:THI RS10560
gene id: 426114:THI_RS10560
uniprot id: D6CUH2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

426114:THI RS05180
gene id: 426114:THI_RS05180
uniprot id: D6CL83
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

426114:THI RS00840
gene id: 426114:THI_RS00840
uniprot id: D6CQP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

426114:THI RS12095
gene id: 426114:THI_RS12095
uniprot id: D6CVD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

426114:THI RS09315
gene id: 426114:THI_RS09315
uniprot id: D6CTS4
names: Similarity
messages: Belongs to the UPF0758 family.

426114:THI RS04135
gene id: 426114:THI_RS04135
uniprot id: D6CS88
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

426114:THI RS04695
gene id: 426114:THI_RS04695
uniprot id: D6CKY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

426114:THI RS01465
gene id: 426114:THI_RS01465
uniprot id: D6CR26
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

426114:THI RS08700
gene id: 426114:THI_RS08700
uniprot id: D6CTE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

426114:THI RS03590
gene id: 426114:THI_RS03590
uniprot id: D6CKN8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

426114:THI RS13930
gene id: 426114:THI_RS13930
uniprot id: D6CM47
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

426114:THI RS05040
gene id: 426114:THI_RS05040
uniprot id: D6CL54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

426114:THI RS04560
gene id: 426114:THI_RS04560
uniprot id: D6CSI1
names: Similarity
messages: Belongs to the histone deacetylase family.

426114:THI RS09585
gene id: 426114:THI_RS09585
uniprot id: D6CTY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

426114:THI RS13615
gene id: 426114:THI_RS13615
uniprot id: D6CLY1
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

426114:THI RS10860
gene id: 426114:THI_RS10860
uniprot id: D6CPQ8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS00585
gene id: 426114:THI_RS00585
uniprot id: D6CQJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell inner membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

426114:THI RS12620
gene id: 426114:THI_RS12620
uniprot id: D6CLD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

426114:THI RS14440
gene id: 426114:THI_RS14440
uniprot id: D6CMF9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

426114:THI RS16630
gene id: 426114:THI_RS16630
uniprot id: D6CNR3
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

426114:THI RS06385
gene id: 426114:THI_RS06385
uniprot id: D6CQ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

426114:THI RS01615
gene id: 426114:THI_RS01615
uniprot id: D6CR55
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

426114:THI RS00390
gene id: 426114:THI_RS00390
uniprot id: D6CKD3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

426114:THI RS09565
gene id: 426114:THI_RS09565
uniprot id: D6CTX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

426114:THI RS06985
gene id: 426114:THI_RS06985
uniprot id: D6CQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

426114:THI RS05045
gene id: 426114:THI_RS05045
uniprot id: D6CL55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

426114:THI RS12315
gene id: 426114:THI_RS12315
uniprot id: D6CVI0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS06545
gene id: 426114:THI_RS06545
uniprot id: D6CPQ7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

426114:THI RS10415
gene id: 426114:THI_RS10415
uniprot id: D6CUE3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

426114:THI RS03875
gene id: 426114:THI_RS03875
uniprot id: D6CKU4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

426114:THI RS01520
gene id: 426114:THI_RS01520
uniprot id: D6CR37
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

426114:THI RS01490
gene id: 426114:THI_RS01490
uniprot id: D6CR31
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS11095
gene id: 426114:THI_RS11095
uniprot id: D6CUT2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

426114:THI RS00730
gene id: 426114:THI_RS00730
uniprot id: D6CQM5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

426114:THI RS09915
gene id: 426114:THI_RS09915
uniprot id: D6CU47
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS00045
gene id: 426114:THI_RS00045
uniprot id: D6CKG1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

426114:THI RS05500
gene id: 426114:THI_RS05500
uniprot id: D6CPG9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

426114:THI RS03075
gene id: 426114:THI_RS03075
uniprot id: D6CS08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

426114:THI RS04970
gene id: 426114:THI_RS04970
uniprot id: D6CL40
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS03825
gene id: 426114:THI_RS03825
uniprot id: D6CKT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

426114:THI RS15180
gene id: 426114:THI_RS15180
uniprot id: D6CMW1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

426114:THI RS00800
gene id: 426114:THI_RS00800
uniprot id: D6CQN9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

426114:THI RS15800
gene id: 426114:THI_RS15800
uniprot id: D6CN88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

426114:THI RS17755
gene id: 426114:THI_RS17755
uniprot id: D6CVS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

426114:THI RS17165
gene id: 426114:THI_RS17165
uniprot id: D6CP25
names: Similarity
messages: Belongs to the TrpC family.

426114:THI RS06940
gene id: 426114:THI_RS06940
uniprot id: D6CQC8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

426114:THI RS15830
gene id: 426114:THI_RS15830
uniprot id: D6CN94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

426114:THI RS07215
gene id: 426114:THI_RS07215
uniprot id: D6CSJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

426114:THI RS01640
gene id: 426114:THI_RS01640
uniprot id: D6CR60
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

426114:THI RS08515
gene id: 426114:THI_RS08515
uniprot id: D6CTA8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

426114:THI RS04385
gene id: 426114:THI_RS04385
uniprot id: D6CSE5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

426114:THI RS12000
gene id: 426114:THI_RS12000
uniprot id: D6CVB7
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS11410
gene id: 426114:THI_RS11410
uniprot id: D6CUZ4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

426114:THI RS10570
gene id: 426114:THI_RS10570
uniprot id: D6CUH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

426114:THI RS13370
gene id: 426114:THI_RS13370
uniprot id: D6CLT4
names: Similarity
messages: Belongs to the CFA/CMAS family.

426114:THI RS13045
gene id: 426114:THI_RS13045
uniprot id: D6CLL5
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

426114:THI RS01910
gene id: 426114:THI_RS01910
uniprot id: D6CRB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

426114:THI RS10055
gene id: 426114:THI_RS10055
uniprot id: D6CU75
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

426114:THI RS12475
gene id: 426114:THI_RS12475
uniprot id: D6CLA2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

426114:THI RS13005
gene id: 426114:THI_RS13005
uniprot id: D6CLK7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

426114:THI RS15225
gene id: 426114:THI_RS15225
uniprot id: D6CMX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

426114:THI RS05670
gene id: 426114:THI_RS05670
uniprot id: D6CPK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

426114:THI RS15780
gene id: 426114:THI_RS15780
uniprot id: D6CN84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

426114:THI RS05095
gene id: 426114:THI_RS05095
uniprot id: D6CL65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

426114:THI RS06115
gene id: 426114:THI_RS06115
uniprot id: D6CPV0
names: Similarity
messages: Belongs to the HesB/IscA family.

426114:THI RS13965
gene id: 426114:THI_RS13965
uniprot id: D6CM54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

426114:THI RS02205
gene id: 426114:THI_RS02205
uniprot id: D6CRH2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

426114:THI RS12610
gene id: 426114:THI_RS12610
uniprot id: D6CLC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

426114:THI RS17610
gene id: 426114:THI_RS17610
uniprot id: D6CPB5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

426114:THI RS14810
gene id: 426114:THI_RS14810
uniprot id: D6CMN7
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS00515
gene id: 426114:THI_RS00515
uniprot id: D6CQI1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

426114:THI RS10600
gene id: 426114:THI_RS10600
uniprot id: D6CUI0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

426114:THI RS07035
gene id: 426114:THI_RS07035
uniprot id: D6CQE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

426114:THI RS02695
gene id: 426114:THI_RS02695
uniprot id: D6CRS5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

426114:THI RS03980
gene id: 426114:THI_RS03980
uniprot id: D6CS55
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

426114:THI RS08435
gene id: 426114:THI_RS08435
uniprot id: D6CT92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

426114:THI RS09850
gene id: 426114:THI_RS09850
uniprot id: D6CU34
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

426114:THI RS05580
gene id: 426114:THI_RS05580
uniprot id: D6CPI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

426114:THI RS11680
gene id: 426114:THI_RS11680
uniprot id: D6CPQ7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

426114:THI RS04655
gene id: 426114:THI_RS04655
uniprot id: D6CKX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

426114:THI RS06930
gene id: 426114:THI_RS06930
uniprot id: D6CQC6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

426114:THI RS16935
gene id: 426114:THI_RS16935
uniprot id: D6CNY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

426114:THI RS15195
gene id: 426114:THI_RS15195
uniprot id: D6CMW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

426114:THI RS08560
gene id: 426114:THI_RS08560
uniprot id: D6CTB8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

426114:THI RS04010
gene id: 426114:THI_RS04010
uniprot id: D6CS61
names: Similarity
messages: Belongs to the glutamate synthase family.

426114:THI RS02100
gene id: 426114:THI_RS02100
uniprot id: D6CRF1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

426114:THI RS10540
gene id: 426114:THI_RS10540
uniprot id: D6CUG8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

426114:THI RS01780
gene id: 426114:THI_RS01780
uniprot id: D6CR88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

426114:THI RS03885
gene id: 426114:THI_RS03885
uniprot id: D6CKU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

426114:THI RS06315
gene id: 426114:THI_RS06315
uniprot id: D6CPZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

426114:THI RS12480
gene id: 426114:THI_RS12480
uniprot id: D6CLA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

426114:THI RS13185
gene id: 426114:THI_RS13185
uniprot id: D6CLP4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

426114:THI RS00170
gene id: 426114:THI_RS00170
uniprot id: D6CVL7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS09990
gene id: 426114:THI_RS09990
uniprot id: D6CU62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

426114:THI RS06975
gene id: 426114:THI_RS06975
uniprot id: D6CQD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

426114:THI RS11240
gene id: 426114:THI_RS11240
uniprot id: D6CUW1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

426114:THI RS01360
gene id: 426114:THI_RS01360
uniprot id: D6CR05
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS12445
gene id: 426114:THI_RS12445
uniprot id: D6CVK5
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

426114:THI RS15595
gene id: 426114:THI_RS15595
uniprot id: D6CN45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

426114:THI RS12945
gene id: 426114:THI_RS12945
uniprot id: D6CLJ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS15155
gene id: 426114:THI_RS15155
uniprot id: D6CMV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

426114:THI RS00060
gene id: 426114:THI_RS00060
uniprot id: D6CKG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

426114:THI RS12410
gene id: 426114:THI_RS12410
uniprot id: D6CVJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS00655
gene id: 426114:THI_RS00655
uniprot id: D6CQL0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

426114:THI RS18665
gene id: 426114:THI_RS18665
uniprot id: D6CPC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

426114:THI RS10400
gene id: 426114:THI_RS10400
uniprot id: D6CUE0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

426114:THI RS12780
gene id: 426114:THI_RS12780
uniprot id: D6CLG2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

426114:THI RS09970
gene id: 426114:THI_RS09970
uniprot id: D6CU59
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

426114:THI RS11300
gene id: 426114:THI_RS11300
uniprot id: D6CUX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

426114:THI RS08105
gene id: 426114:THI_RS08105
uniprot id: D6CT25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

426114:THI RS02535
gene id: 426114:THI_RS02535
uniprot id: D6CRP3
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS05525
gene id: 426114:THI_RS05525
uniprot id: D6CPH3
names: Similarity
messages: Belongs to the GSP E family.

426114:THI RS05065
gene id: 426114:THI_RS05065
uniprot id: D6CL59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

426114:THI RS10115
gene id: 426114:THI_RS10115
uniprot id: D6CU87
names: Similarity
messages: Belongs to the P(II) protein family.

426114:THI RS05195
gene id: 426114:THI_RS05195
uniprot id: D6CL86
names: Similarity
messages: Belongs to the RecJ family.

426114:THI RS09285
gene id: 426114:THI_RS09285
uniprot id: D6CPQ7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

426114:THI RS16460
gene id: 426114:THI_RS16460
uniprot id: D6CNM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

426114:THI RS01070
gene id: 426114:THI_RS01070
uniprot id: A0A8I1MZ95
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS07030
gene id: 426114:THI_RS07030
uniprot id: D6CQE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

426114:THI RS17590
gene id: 426114:THI_RS17590
uniprot id: D6CPB1
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS05435
gene id: 426114:THI_RS05435
uniprot id: D6CPF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

426114:THI RS05460
gene id: 426114:THI_RS05460
uniprot id: D6CPG1
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

426114:THI RS10580
gene id: 426114:THI_RS10580
uniprot id: A0A8I1MTT0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS14155
gene id: 426114:THI_RS14155
uniprot id: D6CM96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

426114:THI RS07910
gene id: 426114:THI_RS07910
uniprot id: D6CSY3
names: Similarity
messages: Belongs to the NodU/CmcH family.

426114:THI RS05265
gene id: 426114:THI_RS05265
uniprot id: D6CPC3
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS11245
gene id: 426114:THI_RS11245
uniprot id: D6CUW2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

426114:THI RS17715
gene id: 426114:THI_RS17715
uniprot id: D6CVR9
names: Function
names: Subcellular Location Annotation
messages: Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
messages: Periplasm

426114:THI RS12205
gene id: 426114:THI_RS12205
uniprot id: D6CVF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

426114:THI RS04865
gene id: 426114:THI_RS04865
uniprot id: D6CL17
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

426114:THI RS15550
gene id: 426114:THI_RS15550
uniprot id: D6CN36
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

426114:THI RS00945
gene id: 426114:THI_RS00945
uniprot id: D6CQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS12300
gene id: 426114:THI_RS12300
uniprot id: D6CVH7
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

426114:THI RS13380
gene id: 426114:THI_RS13380
uniprot id: D6CLT6
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

426114:THI RS03150
gene id: 426114:THI_RS03150
uniprot id: D6CS22
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS01040
gene id: 426114:THI_RS01040
uniprot id: D6CQT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS10510
gene id: 426114:THI_RS10510
uniprot id: D6CUG2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

426114:THI RS13535
gene id: 426114:THI_RS13535
uniprot id: D6CLW6
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

426114:THI RS00410
gene id: 426114:THI_RS00410
uniprot id: D6CKD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

426114:THI RS13355
gene id: 426114:THI_RS13355
uniprot id: D6CLT1
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

426114:THI RS16700
gene id: 426114:THI_RS16700
uniprot id: D6CNS9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

426114:THI RS15320
gene id: 426114:THI_RS15320
uniprot id: D6CMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS00820
gene id: 426114:THI_RS00820
uniprot id: D6CQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

426114:THI RS00445
gene id: 426114:THI_RS00445
uniprot id: D6CKE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

426114:THI RS02400
gene id: 426114:THI_RS02400
uniprot id: D6CRL5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

426114:THI RS01865
gene id: 426114:THI_RS01865
uniprot id: D6CRA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

426114:THI RS17875
gene id: 426114:THI_RS17875
uniprot id: D6CVV8
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS00055
gene id: 426114:THI_RS00055
uniprot id: A0A8I1MYL5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS04400
gene id: 426114:THI_RS04400
uniprot id: D6CSE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

426114:THI RS01885
gene id: 426114:THI_RS01885
uniprot id: D6CRA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

426114:THI RS11755
gene id: 426114:THI_RS11755
uniprot id: D6CV68
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

426114:THI RS09670
gene id: 426114:THI_RS09670
uniprot id: D6CTZ8
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS12020
gene id: 426114:THI_RS12020
uniprot id: D6CVC1
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS09805
gene id: 426114:THI_RS09805
uniprot id: D6CU25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

426114:THI RS08180
gene id: 426114:THI_RS08180
uniprot id: D6CT41
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS13760
gene id: 426114:THI_RS13760
uniprot id: D6CM11
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS08690
gene id: 426114:THI_RS08690
uniprot id: D6CTE4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS10590
gene id: 426114:THI_RS10590
uniprot id: D6CUH8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

426114:THI RS10065
gene id: 426114:THI_RS10065
uniprot id: D6CU77
names: Similarity
messages: Belongs to the YfgM family.

426114:THI RS07070
gene id: 426114:THI_RS07070
uniprot id: D6CQF4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

426114:THI RS06150
gene id: 426114:THI_RS06150
uniprot id: D6CPV8
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

426114:THI RS00610
gene id: 426114:THI_RS00610
uniprot id: D6CQK1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

426114:THI RS12910
gene id: 426114:THI_RS12910
uniprot id: D6CLI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

426114:THI RS14455
gene id: 426114:THI_RS14455
uniprot id: D6CMG2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

426114:THI RS08425
gene id: 426114:THI_RS08425
uniprot id: D6CT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

426114:THI RS07570
gene id: 426114:THI_RS07570
uniprot id: D6CSR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

426114:THI RS09570
gene id: 426114:THI_RS09570
uniprot id: D6CTX8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

426114:THI RS12235
gene id: 426114:THI_RS12235
uniprot id: D6CVG4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

426114:THI RS17600
gene id: 426114:THI_RS17600
uniprot id: D6CPB3
names: Similarity
messages: Belongs to the leucine-binding protein family.

426114:THI RS11275
gene id: 426114:THI_RS11275
uniprot id: D6CUW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

426114:THI RS17595
gene id: 426114:THI_RS17595
uniprot id: D6CPB2
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS13785
gene id: 426114:THI_RS13785
uniprot id: D6CM16
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS03570
gene id: 426114:THI_RS03570
uniprot id: D6CKN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell inner membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

426114:THI RS17400
gene id: 426114:THI_RS17400
uniprot id: D6CP72
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS10260
gene id: 426114:THI_RS10260
uniprot id: D6CUB3
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

426114:THI RS13915
gene id: 426114:THI_RS13915
uniprot id: D6CM44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

426114:THI RS09190
gene id: 426114:THI_RS09190
uniprot id: D6CTP8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

426114:THI RS12520
gene id: 426114:THI_RS12520
uniprot id: D6CLB1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

426114:THI RS03620
gene id: 426114:THI_RS03620
uniprot id: D6CKP4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

426114:THI RS07220
gene id: 426114:THI_RS07220
uniprot id: D6CSJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

426114:THI RS12350
gene id: 426114:THI_RS12350
uniprot id: D6CVI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

426114:THI RS05390
gene id: 426114:THI_RS05390
uniprot id: D6CPE7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

426114:THI RS15070
gene id: 426114:THI_RS15070
uniprot id: D6CMT9
names: Similarity
messages: Belongs to the DinB family.

426114:THI RS00285
gene id: 426114:THI_RS00285
uniprot id: D6CVP3
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS06160
gene id: 426114:THI_RS06160
uniprot id: D6CPW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

426114:THI RS03625
gene id: 426114:THI_RS03625
uniprot id: D6CKP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

426114:THI RS05735
gene id: 426114:THI_RS05735
uniprot id: D6CPM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

426114:THI RS05175
gene id: 426114:THI_RS05175
uniprot id: D6CL82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

426114:THI RS07665
gene id: 426114:THI_RS07665
uniprot id: D6CST5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

426114:THI RS09555
gene id: 426114:THI_RS09555
uniprot id: D6CTX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

426114:THI RS02680
gene id: 426114:THI_RS02680
uniprot id: D6CRS2
names: Similarity
messages: Belongs to the universal stress protein A family.

426114:THI RS14670
gene id: 426114:THI_RS14670
uniprot id: D6CMK5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

426114:THI RS07500
gene id: 426114:THI_RS07500
uniprot id: D6CSQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

426114:THI RS17110
gene id: 426114:THI_RS17110
uniprot id: D6CP18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

426114:THI RS01925
gene id: 426114:THI_RS01925
uniprot id: D6CRB7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

426114:THI RS12440
gene id: 426114:THI_RS12440
uniprot id: D6CVK4
names: Similarity
messages: Belongs to the citrate synthase family.

426114:THI RS17120
gene id: 426114:THI_RS17120
uniprot id: D6CP20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

426114:THI RS14145
gene id: 426114:THI_RS14145
uniprot id: D6CM94
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

426114:THI RS15125
gene id: 426114:THI_RS15125
uniprot id: D6CMV0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

426114:THI RS07475
gene id: 426114:THI_RS07475
uniprot id: D6CSP7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

426114:THI RS15640
gene id: 426114:THI_RS15640
uniprot id: D6CN54
names: Similarity
messages: Belongs to the universal stress protein A family.

426114:THI RS13775
gene id: 426114:THI_RS13775
uniprot id: D6CM14
names: Similarity
messages: Belongs to the SCO1/2 family.

426114:THI RS12290
gene id: 426114:THI_RS12290
uniprot id: D6CVH5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

426114:THI RS04275
gene id: 426114:THI_RS04275
uniprot id: D6CSC1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

426114:THI RS05425
gene id: 426114:THI_RS05425
uniprot id: D6CPF4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

426114:THI RS06485
gene id: 426114:THI_RS06485
uniprot id: D6CQ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

426114:THI RS11290
gene id: 426114:THI_RS11290
uniprot id: D6CUX1
names: Similarity
messages: Belongs to the skp family.

426114:THI RS12360
gene id: 426114:THI_RS12360
uniprot id: D6CVI8
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS16100
gene id: 426114:THI_RS16100
uniprot id: D6CNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

426114:THI RS17935
gene id: 426114:THI_RS17935
uniprot id: D6CVX4
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

426114:THI RS04910
gene id: 426114:THI_RS04910
uniprot id: A0A8I1MTC1
names: Caution
names: Function
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

426114:THI RS09590
gene id: 426114:THI_RS09590
uniprot id: D6CTY2
names: Similarity
messages: Belongs to the UPF0434 family.

426114:THI RS08590
gene id: 426114:THI_RS08590
uniprot id: D6CTC4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

426114:THI RS06720
gene id: 426114:THI_RS06720
uniprot id: D6CQ84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

426114:THI RS12260
gene id: 426114:THI_RS12260
uniprot id: D6CVG9
names: PTM
messages: Binds 1 heme c group covalently per subunit.

426114:THI RS01105
gene id: 426114:THI_RS01105
uniprot id: D6CQV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

426114:THI RS08220
gene id: 426114:THI_RS08220
uniprot id: D6CT49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

426114:THI RS13950
gene id: 426114:THI_RS13950
uniprot id: D6CM51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

426114:THI RS09720
gene id: 426114:THI_RS09720
uniprot id: D6CU08
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS07790
gene id: 426114:THI_RS07790
uniprot id: D6CSV9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

426114:THI RS07550
gene id: 426114:THI_RS07550
uniprot id: D6CSR2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

426114:THI RS12710
gene id: 426114:THI_RS12710
uniprot id: D6CLE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

426114:THI RS03835
gene id: 426114:THI_RS03835
uniprot id: D6CKT5
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

426114:THI RS14855
gene id: 426114:THI_RS14855
uniprot id: D6CMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

426114:THI RS06755
gene id: 426114:THI_RS06755
uniprot id: D6CQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

426114:THI RS12740
gene id: 426114:THI_RS12740
uniprot id: D6CLF4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

426114:THI RS08675
gene id: 426114:THI_RS08675
uniprot id: D6CTE1
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

426114:THI RS11305
gene id: 426114:THI_RS11305
uniprot id: D6CUX4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS05910
gene id: 426114:THI_RS05910
uniprot id: D6CPQ5
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

426114:THI RS14995
gene id: 426114:THI_RS14995
uniprot id: D6CMS4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

426114:THI RS11560
gene id: 426114:THI_RS11560
uniprot id: D6CV27
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS01595
gene id: 426114:THI_RS01595
uniprot id: D6CR51
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

426114:THI RS07655
gene id: 426114:THI_RS07655
uniprot id: D6CST3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

426114:THI RS14350
gene id: 426114:THI_RS14350
uniprot id: D6CMD8
names: Similarity
messages: Belongs to the peptidase C56 family.

426114:THI RS00635
gene id: 426114:THI_RS00635
uniprot id: D6CQK6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

426114:THI RS09580
gene id: 426114:THI_RS09580
uniprot id: D6CTY0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

426114:THI RS12825
gene id: 426114:THI_RS12825
uniprot id: D6CLH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

426114:THI RS03070
gene id: 426114:THI_RS03070
uniprot id: D6CS07
names: Similarity
messages: Belongs to the ABC transporter superfamily.

426114:THI RS04530
gene id: 426114:THI_RS04530
uniprot id: D6CSH5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

426114:THI RS03335
gene id: 426114:THI_RS03335
uniprot id: D6CKI5
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS11900
gene id: 426114:THI_RS11900
uniprot id: D6CV97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

426114:THI RS00825
gene id: 426114:THI_RS00825
uniprot id: D6CQP4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

426114:THI RS04650
gene id: 426114:THI_RS04650
uniprot id: D6CKX4
names: Similarity
messages: Belongs to the Dps family.

426114:THI RS09500
gene id: 426114:THI_RS09500
uniprot id: D6CTW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

426114:THI RS14170
gene id: 426114:THI_RS14170
uniprot id: D6CM99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS08000
gene id: 426114:THI_RS08000
uniprot id: D6CT04
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

426114:THI RS13350
gene id: 426114:THI_RS13350
uniprot id: D6CLT0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

426114:THI RS01290
gene id: 426114:THI_RS01290
uniprot id: D6CQY9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

426114:THI RS13460
gene id: 426114:THI_RS13460
uniprot id: D6CLV1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

426114:THI RS13835
gene id: 426114:THI_RS13835
uniprot id: D6CM27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

426114:THI RS15760
gene id: 426114:THI_RS15760
uniprot id: D6CN80
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS02470
gene id: 426114:THI_RS02470
uniprot id: D6CRN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

426114:THI RS11535
gene id: 426114:THI_RS11535
uniprot id: D6CV22
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

426114:THI RS06390
gene id: 426114:THI_RS06390
uniprot id: D6CQ05
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

426114:THI RS15335
gene id: 426114:THI_RS15335
uniprot id: D6CMZ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

426114:THI RS05125
gene id: 426114:THI_RS05125
uniprot id: D6CL72
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

426114:THI RS06680
gene id: 426114:THI_RS06680
uniprot id: D6CQ76
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

426114:THI RS06895
gene id: 426114:THI_RS06895
uniprot id: D6CQB9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

426114:THI RS04605
gene id: 426114:THI_RS04605
uniprot id: D6CKW5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

426114:THI RS09890
gene id: 426114:THI_RS09890
uniprot id: D6CU42
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

426114:THI RS11100
gene id: 426114:THI_RS11100
uniprot id: D6CUT3
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS04260
gene id: 426114:THI_RS04260
uniprot id: D6CSB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

426114:THI RS04770
gene id: 426114:THI_RS04770
uniprot id: D6CKZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

426114:THI RS15455
gene id: 426114:THI_RS15455
uniprot id: D6CN16
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS10615
gene id: 426114:THI_RS10615
uniprot id: D6CUI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

426114:THI RS12900
gene id: 426114:THI_RS12900
uniprot id: D6CLI6
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

426114:THI RS06925
gene id: 426114:THI_RS06925
uniprot id: D6CQC5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

426114:THI RS15510
gene id: 426114:THI_RS15510
uniprot id: D6CN28
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

426114:THI RS12495
gene id: 426114:THI_RS12495
uniprot id: D6CLA6
names: Similarity
messages: Belongs to the PrpD family.

426114:THI RS09575
gene id: 426114:THI_RS09575
uniprot id: D6CTX9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

426114:THI RS13500
gene id: 426114:THI_RS13500
uniprot id: D6CLV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

426114:THI RS02550
gene id: 426114:THI_RS02550
uniprot id: D6CRP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

426114:THI RS00275
gene id: 426114:THI_RS00275
uniprot id: D6CVP0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

426114:THI RS15675
gene id: 426114:THI_RS15675
uniprot id: D6CN61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

426114:THI RS02670
gene id: 426114:THI_RS02670
uniprot id: D6CRS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

426114:THI RS12100
gene id: 426114:THI_RS12100
uniprot id: D6CVD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

426114:THI RS04060
gene id: 426114:THI_RS04060
uniprot id: D6CS71
names: Similarity
messages: Belongs to the PspA/IM30 family.

426114:THI RS15305
gene id: 426114:THI_RS15305
uniprot id: D6CMY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

426114:THI RS02830
gene id: 426114:THI_RS02830
uniprot id: D6CNY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

426114:THI RS01450
gene id: 426114:THI_RS01450
uniprot id: D6CR23
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

426114:THI RS09655
gene id: 426114:THI_RS09655
uniprot id: D6CTZ5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

426114:THI RS13475
gene id: 426114:THI_RS13475
uniprot id: D6CLV4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS17285
gene id: 426114:THI_RS17285
uniprot id: D6CP49
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

426114:THI RS11180
gene id: 426114:THI_RS11180
uniprot id: D6CUU9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

426114:THI RS03175
gene id: 426114:THI_RS03175
uniprot id: D6CS27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

426114:THI RS09950
gene id: 426114:THI_RS09950
uniprot id: D6CU55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

426114:THI RS08045
gene id: 426114:THI_RS08045
uniprot id: D6CT13
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

426114:THI RS07965
gene id: 426114:THI_RS07965
uniprot id: D6CSZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS08340
gene id: 426114:THI_RS08340
uniprot id: D6CT73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS12765
gene id: 426114:THI_RS12765
uniprot id: D6CLF9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

426114:THI RS11505
gene id: 426114:THI_RS11505
uniprot id: D6CV16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

426114:THI RS05430
gene id: 426114:THI_RS05430
uniprot id: D6CPF5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

426114:THI RS11815
gene id: 426114:THI_RS11815
uniprot id: D6CV81
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

426114:THI RS14925
gene id: 426114:THI_RS14925
uniprot id: D6CMR0
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

426114:THI RS05850
gene id: 426114:THI_RS05850
uniprot id: D6CPP3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

426114:THI RS07300
gene id: 426114:THI_RS07300
uniprot id: D6CSL2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS10315
gene id: 426114:THI_RS10315
uniprot id: D6CUC4
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

426114:THI RS15755
gene id: 426114:THI_RS15755
uniprot id: D6CN79
names: Similarity
messages: Belongs to the TPP enzyme family.

426114:THI RS09830
gene id: 426114:THI_RS09830
uniprot id: D6CU30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

426114:THI RS17805
gene id: 426114:THI_RS17805
uniprot id: D6CVU0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS12185
gene id: 426114:THI_RS12185
uniprot id: D6CVF4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

426114:THI RS08010
gene id: 426114:THI_RS08010
uniprot id: D6CT06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

426114:THI RS12895
gene id: 426114:THI_RS12895
uniprot id: D6CLI5
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS15925
gene id: 426114:THI_RS15925
uniprot id: D6CNA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

426114:THI RS01250
gene id: 426114:THI_RS01250
uniprot id: D6CQY0
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS12665
gene id: 426114:THI_RS12665
uniprot id: D6CLD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

426114:THI RS02040
gene id: 426114:THI_RS02040
uniprot id: A0A8I1MU68
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS12525
gene id: 426114:THI_RS12525
uniprot id: D6CLB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

426114:THI RS00705
gene id: 426114:THI_RS00705
uniprot id: D6CQM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS15040
gene id: 426114:THI_RS15040
uniprot id: D6CMT3
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

426114:THI RS01915
gene id: 426114:THI_RS01915
uniprot id: D6CRB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

426114:THI RS01530
gene id: 426114:THI_RS01530
uniprot id: D6CR39
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

426114:THI RS13555
gene id: 426114:THI_RS13555
uniprot id: D6CLX0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

426114:THI RS03975
gene id: 426114:THI_RS03975
uniprot id: D6CS54
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

426114:THI RS11610
gene id: 426114:THI_RS11610
uniprot id: D6CV37
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

426114:THI RS03905
gene id: 426114:THI_RS03905
uniprot id: D6CKV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS16120
gene id: 426114:THI_RS16120
uniprot id: D6CNF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS14970
gene id: 426114:THI_RS14970
uniprot id: D6CMR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

426114:THI RS16620
gene id: 426114:THI_RS16620
uniprot id: D6CNR1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

426114:THI RS01340
gene id: 426114:THI_RS01340
uniprot id: D6CQZ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

426114:THI RS01170
gene id: 426114:THI_RS01170
uniprot id: D6CQW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

426114:THI RS03820
gene id: 426114:THI_RS03820
uniprot id: D6CKT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

426114:THI RS09345
gene id: 426114:THI_RS09345
uniprot id: D6CTT0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type II subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In contrast to form I RuBisCO, the form II RuBisCO are composed solely of large subunits.

426114:THI RS12685
gene id: 426114:THI_RS12685
uniprot id: D6CLE3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

426114:THI RS06945
gene id: 426114:THI_RS06945
uniprot id: D6CQC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

426114:THI RS15165
gene id: 426114:THI_RS15165
uniprot id: D6CMV8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

426114:THI RS15825
gene id: 426114:THI_RS15825
uniprot id: D6CN93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

426114:THI RS04595
gene id: 426114:THI_RS04595
uniprot id: D6CKW3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

426114:THI RS07370
gene id: 426114:THI_RS07370
uniprot id: D6CSM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

426114:THI RS13710
gene id: 426114:THI_RS13710
uniprot id: D6CM00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

426114:THI RS02625
gene id: 426114:THI_RS02625
uniprot id: D6CRR1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

426114:THI RS15230
gene id: 426114:THI_RS15230
uniprot id: D6CMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

426114:THI RS00720
gene id: 426114:THI_RS00720
uniprot id: D6CQM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

426114:THI RS02690
gene id: 426114:THI_RS02690
uniprot id: D6CRS4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

426114:THI RS10620
gene id: 426114:THI_RS10620
uniprot id: D6CUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

426114:THI RS01485
gene id: 426114:THI_RS01485
uniprot id: D6CR30
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS16535
gene id: 426114:THI_RS16535
uniprot id: D6CNP3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

426114:THI RS12860
gene id: 426114:THI_RS12860
uniprot id: D6CLH8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

426114:THI RS11330
gene id: 426114:THI_RS11330
uniprot id: D6CUX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

426114:THI RS10800
gene id: 426114:THI_RS10800
uniprot id: D6CUM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS14205
gene id: 426114:THI_RS14205
uniprot id: D6CMA8
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS08615
gene id: 426114:THI_RS08615
uniprot id: D6CTC9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

426114:THI RS12800
gene id: 426114:THI_RS12800
uniprot id: D6CLG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

426114:THI RS11590
gene id: 426114:THI_RS11590
uniprot id: D6CV33
names: Similarity
messages: Belongs to the pyruvate kinase family.

426114:THI RS01220
gene id: 426114:THI_RS01220
uniprot id: D6CQX4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

426114:THI RS09825
gene id: 426114:THI_RS09825
uniprot id: D6CU29
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

426114:THI RS12080
gene id: 426114:THI_RS12080
uniprot id: A0A8I1SSY5
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS07695
gene id: 426114:THI_RS07695
uniprot id: D6CSU1
names: Similarity
messages: Belongs to the WrbA family.

426114:THI RS14625
gene id: 426114:THI_RS14625
uniprot id: D6CMJ6
names: Similarity
messages: Belongs to the AOR/FOR family.

426114:THI RS12925
gene id: 426114:THI_RS12925
uniprot id: D6CLJ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

426114:THI RS15690
gene id: 426114:THI_RS15690
uniprot id: D6CN64
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

426114:THI RS16210
gene id: 426114:THI_RS16210
uniprot id: D6CNH2
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS05245
gene id: 426114:THI_RS05245
uniprot id: D6CL96
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

426114:THI RS12785
gene id: 426114:THI_RS12785
uniprot id: D6CLG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

426114:THI RS00025
gene id: 426114:THI_RS00025
uniprot id: D6CKF7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

426114:THI RS03485
gene id: 426114:THI_RS03485
uniprot id: D6CKL7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

426114:THI RS10765
gene id: 426114:THI_RS10765
uniprot id: D6CUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS04310
gene id: 426114:THI_RS04310
uniprot id: D6CPQ7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

426114:THI RS17235
gene id: 426114:THI_RS17235
uniprot id: D6CP39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

426114:THI RS02185
gene id: 426114:THI_RS02185
uniprot id: D6CRG8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

426114:THI RS12820
gene id: 426114:THI_RS12820
uniprot id: A0A8I1SVL1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS05550
gene id: 426114:THI_RS05550
uniprot id: D6CPI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

426114:THI RS15445
gene id: 426114:THI_RS15445
uniprot id: D6CN14
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

426114:THI RS12745
gene id: 426114:THI_RS12745
uniprot id: D6CLF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

426114:THI RS17135
gene id: 426114:THI_RS17135
uniprot id: D6CP23
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS03565
gene id: 426114:THI_RS03565
uniprot id: D6CKN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS05235
gene id: 426114:THI_RS05235
uniprot id: D6CL94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

426114:THI RS02030
gene id: 426114:THI_RS02030
uniprot id: D6CRD7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

426114:THI RS06850
gene id: 426114:THI_RS06850
uniprot id: D6CQB2
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

426114:THI RS03815
gene id: 426114:THI_RS03815
uniprot id: D6CKT1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

426114:THI RS15235
gene id: 426114:THI_RS15235
uniprot id: D6CMX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

426114:THI RS14825
gene id: 426114:THI_RS14825
uniprot id: D6CMP0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

426114:THI RS14525
gene id: 426114:THI_RS14525
uniprot id: D6CMH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

426114:THI RS02645
gene id: 426114:THI_RS02645
uniprot id: D6CRR5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

426114:THI RS08075
gene id: 426114:THI_RS08075
uniprot id: D6CT19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS08225
gene id: 426114:THI_RS08225
uniprot id: D6CT50
names: Function
names: Subcellular Location Annotation
messages: Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
messages: Periplasm

426114:THI RS05810
gene id: 426114:THI_RS05810
uniprot id: D6CPN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

426114:THI RS13585
gene id: 426114:THI_RS13585
uniprot id: D6CLX6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

426114:THI RS07055
gene id: 426114:THI_RS07055
uniprot id: D6CQF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

426114:THI RS08120
gene id: 426114:THI_RS08120
uniprot id: D6CT28
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS13770
gene id: 426114:THI_RS13770
uniprot id: D6CM13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

426114:THI RS09880
gene id: 426114:THI_RS09880
uniprot id: D6CU40
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS09730
gene id: 426114:THI_RS09730
uniprot id: D6CU10
names: Similarity
messages: Belongs to the UPF0166 family.

426114:THI RS03370
gene id: 426114:THI_RS03370
uniprot id: D6CKJ2
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

426114:THI RS01205
gene id: 426114:THI_RS01205
uniprot id: A0A8I1MV28
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS13235
gene id: 426114:THI_RS13235
uniprot id: D6CLQ5
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS00460
gene id: 426114:THI_RS00460
uniprot id: D6CKE8
names: Similarity
messages: Belongs to the Smg family.

426114:THI RS07110
gene id: 426114:THI_RS07110
uniprot id: D6CQG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

426114:THI RS08065
gene id: 426114:THI_RS08065
uniprot id: D6CT17
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

426114:THI RS13440
gene id: 426114:THI_RS13440
uniprot id: D6CLU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

426114:THI RS02565
gene id: 426114:THI_RS02565
uniprot id: D6CRP9
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS12485
gene id: 426114:THI_RS12485
uniprot id: D6CLA4
names: Similarity
messages: Belongs to the citrate synthase family.

426114:THI RS01180
gene id: 426114:THI_RS01180
uniprot id: D6CQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS10325
gene id: 426114:THI_RS10325
uniprot id: D6CUC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

426114:THI RS14870
gene id: 426114:THI_RS14870
uniprot id: D6CMP9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

426114:THI RS12125
gene id: 426114:THI_RS12125
uniprot id: D6CVE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

426114:THI RS15375
gene id: 426114:THI_RS15375
uniprot id: D6CN00
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

426114:THI RS12955
gene id: 426114:THI_RS12955
uniprot id: D6CLJ7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

426114:THI RS13910
gene id: 426114:THI_RS13910
uniprot id: D6CM42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

426114:THI RS15810
gene id: 426114:THI_RS15810
uniprot id: D6CN90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

426114:THI RS11865
gene id: 426114:THI_RS11865
uniprot id: D6CV90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

426114:THI RS12380
gene id: 426114:THI_RS12380
uniprot id: D6CVJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

426114:THI RS11935
gene id: 426114:THI_RS11935
uniprot id: D6CVA4
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS15300
gene id: 426114:THI_RS15300
uniprot id: D6CMY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

426114:THI RS15750
gene id: 426114:THI_RS15750
uniprot id: D6CN78
names: Similarity
messages: Belongs to the hyi family.

426114:THI RS06640
gene id: 426114:THI_RS06640
uniprot id: D6CQ67
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

426114:THI RS12865
gene id: 426114:THI_RS12865
uniprot id: D6CLH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

426114:THI RS01840
gene id: 426114:THI_RS01840
uniprot id: D6CR99
names: Similarity
messages: Belongs to the ABC transporter superfamily.

426114:THI RS06890
gene id: 426114:THI_RS06890
uniprot id: D6CQB8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

426114:THI RS15880
gene id: 426114:THI_RS15880
uniprot id: D6CNA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

426114:THI RS09035
gene id: 426114:THI_RS09035
uniprot id: D6CTL4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

426114:THI RS09715
gene id: 426114:THI_RS09715
uniprot id: D6CU07
names: Similarity
messages: Belongs to the FrhG family.

426114:THI RS01635
gene id: 426114:THI_RS01635
uniprot id: D6CR59
names: Similarity
messages: Belongs to the ABC transporter superfamily.

426114:THI RS06085
gene id: 426114:THI_RS06085
uniprot id: D6CPU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

426114:THI RS13890
gene id: 426114:THI_RS13890
uniprot id: D6CM38
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

426114:THI RS00645
gene id: 426114:THI_RS00645
uniprot id: A0A8I1SVV4
names: Caution
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

426114:THI RS07445
gene id: 426114:THI_RS07445
uniprot id: D6CSP1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

426114:THI RS12115
gene id: 426114:THI_RS12115
uniprot id: D6CVD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

426114:THI RS13070
gene id: 426114:THI_RS13070
uniprot id: D6CLM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

426114:THI RS13325
gene id: 426114:THI_RS13325
uniprot id: D6CLS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS12950
gene id: 426114:THI_RS12950
uniprot id: D6CLJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

426114:THI RS04345
gene id: 426114:THI_RS04345
uniprot id: D6CSD7
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

426114:THI RS05700
gene id: 426114:THI_RS05700
uniprot id: D6CPL3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

426114:THI RS10000
gene id: 426114:THI_RS10000
uniprot id: D6CU64
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

426114:THI RS01770
gene id: 426114:THI_RS01770
uniprot id: D6CR86
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

426114:THI RS10995
gene id: 426114:THI_RS10995
uniprot id: D6CUR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

426114:THI RS17280
gene id: 426114:THI_RS17280
uniprot id: D6CP48
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS00925
gene id: 426114:THI_RS00925
uniprot id: D6CQR4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

426114:THI RS01795
gene id: 426114:THI_RS01795
uniprot id: D6CR91
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

426114:THI RS04540
gene id: 426114:THI_RS04540
uniprot id: D6CSH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

426114:THI RS13900
gene id: 426114:THI_RS13900
uniprot id: D6CM40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

426114:THI RS07760
gene id: 426114:THI_RS07760
uniprot id: D6CSV3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

426114:THI RS14480
gene id: 426114:THI_RS14480
uniprot id: D6CMG7
names: Function
names: Similarity
messages: Anion-transporting ATPase.
messages: Belongs to the arsA ATPase family.

426114:THI RS11060
gene id: 426114:THI_RS11060
uniprot id: D6CUS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS03600
gene id: 426114:THI_RS03600
uniprot id: D6CKP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

426114:THI RS03860
gene id: 426114:THI_RS03860
uniprot id: D6CKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Homododecamer. Tetramer of trimer.
messages: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.

426114:THI RS01935
gene id: 426114:THI_RS01935
uniprot id: D6CRB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

426114:THI RS05705
gene id: 426114:THI_RS05705
uniprot id: D6CPL4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

426114:THI RS03635
gene id: 426114:THI_RS03635
uniprot id: D6CKP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

426114:THI RS11515
gene id: 426114:THI_RS11515
uniprot id: D6CV18
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

426114:THI RS03765
gene id: 426114:THI_RS03765
uniprot id: D6CKS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

426114:THI RS13805
gene id: 426114:THI_RS13805
uniprot id: D6CM20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

426114:THI RS12355
gene id: 426114:THI_RS12355
uniprot id: D6CVI7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS02385
gene id: 426114:THI_RS02385
uniprot id: D6CRL1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

426114:THI RS03105
gene id: 426114:THI_RS03105
uniprot id: D6CS14
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS12970
gene id: 426114:THI_RS12970
uniprot id: D6CLK0
names: Similarity
messages: Belongs to the lipid A palmitoyltransferase family.

426114:THI RS04965
gene id: 426114:THI_RS04965
uniprot id: D6CL39
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS16985
gene id: 426114:THI_RS16985
uniprot id: D6CNZ3
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

426114:THI RS15430
gene id: 426114:THI_RS15430
uniprot id: D6CN11
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS01755
gene id: 426114:THI_RS01755
uniprot id: D6CR83
names: Similarity
messages: Belongs to the GSP E family.

426114:THI RS07260
gene id: 426114:THI_RS07260
uniprot id: D6CSK4
names: Subcellular Location Annotation
messages: Periplasm

426114:THI RS12455
gene id: 426114:THI_RS12455
uniprot id: D6CL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

426114:THI RS02985
gene id: 426114:THI_RS02985
uniprot id: D6CRY9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS10090
gene id: 426114:THI_RS10090
uniprot id: D6CU82
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

426114:THI RS17545
gene id: 426114:THI_RS17545
uniprot id: D6CPA2
names: Similarity
messages: Belongs to the thioredoxin family.

426114:THI RS10075
gene id: 426114:THI_RS10075
uniprot id: D6CU79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

426114:THI RS13515
gene id: 426114:THI_RS13515
uniprot id: D6CLW2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS07980
gene id: 426114:THI_RS07980
uniprot id: D6CT00
names: Cofactor
messages: Can also use Mn(2+) ion.

426114:THI RS16500
gene id: 426114:THI_RS16500
uniprot id: D6CNN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

426114:THI RS12050
gene id: 426114:THI_RS12050
uniprot id: D6CVC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

426114:THI RS13960
gene id: 426114:THI_RS13960
uniprot id: D6CM53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

426114:THI RS13015
gene id: 426114:THI_RS13015
uniprot id: D6CLK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

426114:THI RS08155
gene id: 426114:THI_RS08155
uniprot id: D6CT35
names: Similarity
messages: Belongs to the universal stress protein A family.

426114:THI RS13610
gene id: 426114:THI_RS13610
uniprot id: D6CLY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

426114:THI RS01650
gene id: 426114:THI_RS01650
uniprot id: D6CR62
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

426114:THI RS02155
gene id: 426114:THI_RS02155
uniprot id: D6CPR5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS09785
gene id: 426114:THI_RS09785
uniprot id: D6CU21
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

426114:THI RS01950
gene id: 426114:THI_RS01950
uniprot id: D6CRC2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

426114:THI RS12795
gene id: 426114:THI_RS12795
uniprot id: D6CLG5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

426114:THI RS12040
gene id: 426114:THI_RS12040
uniprot id: D6CVC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

426114:THI RS00020
gene id: 426114:THI_RS00020
uniprot id: D6CKF6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

426114:THI RS14710
gene id: 426114:THI_RS14710
uniprot id: D6CML2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

426114:THI RS09795
gene id: 426114:THI_RS09795
uniprot id: D6CU23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

426114:THI RS03650
gene id: 426114:THI_RS03650
uniprot id: D6CKQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

426114:THI RS09780
gene id: 426114:THI_RS09780
uniprot id: D6CU20
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

426114:THI RS00510
gene id: 426114:THI_RS00510
uniprot id: D6CQI0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

426114:THI RS06320
gene id: 426114:THI_RS06320
uniprot id: D6CPZ1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

426114:THI RS00010
gene id: 426114:THI_RS00010
uniprot id: D6CKF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

426114:THI RS01535
gene id: 426114:THI_RS01535
uniprot id: D6CR40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

426114:THI RS16750
gene id: 426114:THI_RS16750
uniprot id: D6CNU1
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS00935
gene id: 426114:THI_RS00935
uniprot id: D6CQR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

426114:THI RS17705
gene id: 426114:THI_RS17705
uniprot id: D6CVR7
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

426114:THI RS05240
gene id: 426114:THI_RS05240
uniprot id: D6CL95
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

426114:THI RS00135
gene id: 426114:THI_RS00135
uniprot id: D6CVK8
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

426114:THI RS06140
gene id: 426114:THI_RS06140
uniprot id: D6CPV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

426114:THI RS01960
gene id: 426114:THI_RS01960
uniprot id: D6CRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

426114:THI RS14895
gene id: 426114:THI_RS14895
uniprot id: D6CMQ4
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

426114:THI RS15955
gene id: 426114:THI_RS15955
uniprot id: D6CNB5
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

426114:THI RS02020
gene id: 426114:THI_RS02020
uniprot id: D6CRD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

426114:THI RS10230
gene id: 426114:THI_RS10230
uniprot id: D6CUA7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

426114:THI RS01920
gene id: 426114:THI_RS01920
uniprot id: D6CRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

426114:THI RS15730
gene id: 426114:THI_RS15730
uniprot id: D6CN74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS13085
gene id: 426114:THI_RS13085
uniprot id: D6CLM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS07490
gene id: 426114:THI_RS07490
uniprot id: D6CSQ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

426114:THI RS02975
gene id: 426114:THI_RS02975
uniprot id: D6CRY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

426114:THI RS17205
gene id: 426114:THI_RS17205
uniprot id: D6CP33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

426114:THI RS14720
gene id: 426114:THI_RS14720
uniprot id: D6CML4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

426114:THI RS15465
gene id: 426114:THI_RS15465
uniprot id: D6CN18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

426114:THI RS03320
gene id: 426114:THI_RS03320
uniprot id: D6CKI2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS06770
gene id: 426114:THI_RS06770
uniprot id: D6CQ95
names: Similarity
messages: Belongs to the type III secretion exporter family.

426114:THI RS00435
gene id: 426114:THI_RS00435
uniprot id: D6CKE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

426114:THI RS03880
gene id: 426114:THI_RS03880
uniprot id: D6CKU5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

426114:THI RS10140
gene id: 426114:THI_RS10140
uniprot id: D6CU92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

426114:THI RS14555
gene id: 426114:THI_RS14555
uniprot id: D6CMI2
names: PTM
messages: Binds 1 heme c group covalently per subunit.

426114:THI RS04900
gene id: 426114:THI_RS04900
uniprot id: D6CL25
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

426114:THI RS11455
gene id: 426114:THI_RS11455
uniprot id: D6CV04
names: Similarity
messages: Belongs to the peptidase U62 family.

426114:THI RS05345
gene id: 426114:THI_RS05345
uniprot id: D6CPD8
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

426114:THI RS07590
gene id: 426114:THI_RS07590
uniprot id: D6CSS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

426114:THI RS11230
gene id: 426114:THI_RS11230
uniprot id: D6CUV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

426114:THI RS05070
gene id: 426114:THI_RS05070
uniprot id: D6CL60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

426114:THI RS00815
gene id: 426114:THI_RS00815
uniprot id: D6CQP2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

426114:THI RS03800
gene id: 426114:THI_RS03800
uniprot id: D6CKS8
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

426114:THI RS07585
gene id: 426114:THI_RS07585
uniprot id: D6CSS0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

426114:THI RS15120
gene id: 426114:THI_RS15120
uniprot id: D6CMU9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

426114:THI RS02110
gene id: 426114:THI_RS02110
uniprot id: D6CRF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

426114:THI RS15020
gene id: 426114:THI_RS15020
uniprot id: D6CMS9
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

426114:THI RS00005
gene id: 426114:THI_RS00005
uniprot id: D6CKF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

426114:THI RS12015
gene id: 426114:THI_RS12015
uniprot id: D6CVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

426114:THI RS13845
gene id: 426114:THI_RS13845
uniprot id: D6CM29
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

426114:THI RS04675
gene id: 426114:THI_RS04675
uniprot id: D6CKX9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

426114:THI RS17270
gene id: 426114:THI_RS17270
uniprot id: D6CP46
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

426114:THI RS16790
gene id: 426114:THI_RS16790
uniprot id: D6CNU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS03870
gene id: 426114:THI_RS03870
uniprot id: D6CKU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

426114:THI RS17180
gene id: 426114:THI_RS17180
uniprot id: D6CP28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

426114:THI RS05370
gene id: 426114:THI_RS05370
uniprot id: D6CPE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

426114:THI RS13895
gene id: 426114:THI_RS13895
uniprot id: D6CM39
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

426114:THI RS12690
gene id: 426114:THI_RS12690
uniprot id: D6CLE4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

426114:THI RS05640
gene id: 426114:THI_RS05640
uniprot id: D6CPK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

426114:THI RS04020
gene id: 426114:THI_RS04020
uniprot id: D6CS63
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

426114:THI RS13745
gene id: 426114:THI_RS13745
uniprot id: D6CM08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

426114:THI RS05260
gene id: 426114:THI_RS05260
uniprot id: D6CPC2
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS04680
gene id: 426114:THI_RS04680
uniprot id: D6CKY0
names: Similarity
messages: Belongs to the peptidase C56 family.

426114:THI RS05955
gene id: 426114:THI_RS05955
uniprot id: D6CPR5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

426114:THI RS03520
gene id: 426114:THI_RS03520
uniprot id: D6CKM4
names: Similarity
messages: Belongs to the leucine-binding protein family.

426114:THI RS03770
gene id: 426114:THI_RS03770
uniprot id: D6CKS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

426114:THI RS14165
gene id: 426114:THI_RS14165
uniprot id: D6CM98
names: Function
names: Subcellular Location Annotation
messages: Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
messages: Periplasm

426114:THI RS05030
gene id: 426114:THI_RS05030
uniprot id: D6CL52
names: Similarity
messages: Belongs to the BolA/IbaG family.

426114:THI RS06125
gene id: 426114:THI_RS06125
uniprot id: D6CPV2
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

426114:THI RS01060
gene id: 426114:THI_RS01060
uniprot id: D6CQU1
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

426114:THI RS07150
gene id: 426114:THI_RS07150
uniprot id: D6CQH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

426114:THI RS14860
gene id: 426114:THI_RS14860
uniprot id: D6CMP7
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS11825
gene id: 426114:THI_RS11825
uniprot id: D6CV82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

426114:THI RS02305
gene id: 426114:THI_RS02305
uniprot id: D6CRJ5
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

426114:THI RS07130
gene id: 426114:THI_RS07130
uniprot id: D6CQG6
names: Similarity
messages: Belongs to the asparaginase 1 family.

426114:THI RS00475
gene id: 426114:THI_RS00475
uniprot id: D6CKF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

426114:THI RS14560
gene id: 426114:THI_RS14560
uniprot id: A4FT63
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

426114:THI RS05900
gene id: 426114:THI_RS05900
uniprot id: D6CPQ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

426114:THI RS13995
gene id: 426114:THI_RS13995
uniprot id: D6CM61
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.

426114:THI RS05740
gene id: 426114:THI_RS05740
uniprot id: D6CPM1
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

426114:THI RS00735
gene id: 426114:THI_RS00735
uniprot id: D6CQM6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

426114:THI RS13875
gene id: 426114:THI_RS13875
uniprot id: D6CM35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

426114:THI RS15395
gene id: 426114:THI_RS15395
uniprot id: D6CN04
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

426114:THI RS17360
gene id: 426114:THI_RS17360
uniprot id: D6CP64
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS06350
gene id: 426114:THI_RS06350
uniprot id: D6CPZ7
names: Similarity
messages: Belongs to the disproportionating enzyme family.

426114:THI RS18210
gene id: 426114:THI_RS18210
uniprot id: D6CVR1
names: Similarity
messages: Belongs to the ParB family.

426114:THI RS00035
gene id: 426114:THI_RS00035
uniprot id: D6CKF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

426114:THI RS06920
gene id: 426114:THI_RS06920
uniprot id: D6CQC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

426114:THI RS07895
gene id: 426114:THI_RS07895
uniprot id: D6CSX9
names: Similarity
messages: Belongs to the autoinducer synthase family.

426114:THI RS11295
gene id: 426114:THI_RS11295
uniprot id: D6CUX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

426114:THI RS14460
gene id: 426114:THI_RS14460
uniprot id: D6CMG3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS01015
gene id: 426114:THI_RS01015
uniprot id: D6CQT2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

426114:THI RS15845
gene id: 426114:THI_RS15845
uniprot id: D6CN97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

426114:THI RS06990
gene id: 426114:THI_RS06990
uniprot id: D6CQD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

426114:THI RS07045
gene id: 426114:THI_RS07045
uniprot id: D6CQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

426114:THI RS05615
gene id: 426114:THI_RS05615
uniprot id: D6CPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS04775
gene id: 426114:THI_RS04775
uniprot id: D6CKZ9
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS18055
gene id: 426114:THI_RS18055
uniprot id: D6CPS0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

426114:THI RS11570
gene id: 426114:THI_RS11570
uniprot id: D6CV29
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS01045
gene id: 426114:THI_RS01045
uniprot id: D6CQT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

426114:THI RS00140
gene id: 426114:THI_RS00140
uniprot id: D6CVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

426114:THI RS04495
gene id: 426114:THI_RS04495
uniprot id: D6CSG7
names: Similarity
messages: Belongs to the UPF0250 family.

426114:THI RS09760
gene id: 426114:THI_RS09760
uniprot id: D6CU16
names: Similarity
messages: Belongs to the CFA/CMAS family.

426114:THI RS03750
gene id: 426114:THI_RS03750
uniprot id: D6CKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS08390
gene id: 426114:THI_RS08390
uniprot id: D6CT83
names: Similarity
messages: Belongs to the BolA/IbaG family.

426114:THI RS05275
gene id: 426114:THI_RS05275
uniprot id: D6CPC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

426114:THI RS00185
gene id: 426114:THI_RS00185
uniprot id: D6CVM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

426114:THI RS08500
gene id: 426114:THI_RS08500
uniprot id: D6CTA5
names: Subcellular Location Annotation
messages: Periplasm

426114:THI RS14875
gene id: 426114:THI_RS14875
uniprot id: D6CMQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

426114:THI RS01810
gene id: 426114:THI_RS01810
uniprot id: D6CR93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

426114:THI RS12425
gene id: 426114:THI_RS12425
uniprot id: D6CVK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

426114:THI RS12985
gene id: 426114:THI_RS12985
uniprot id: D6CLK3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

426114:THI RS10060
gene id: 426114:THI_RS10060
uniprot id: D6CU76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

426114:THI RS00975
gene id: 426114:THI_RS00975
uniprot id: D6CQS4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

426114:THI RS14745
gene id: 426114:THI_RS14745
uniprot id: D6CML9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

426114:THI RS12725
gene id: 426114:THI_RS12725
uniprot id: D6CLF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

426114:THI RS13570
gene id: 426114:THI_RS13570
uniprot id: D6CLX3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

426114:THI RS02510
gene id: 426114:THI_RS02510
uniprot id: D6CRN8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

426114:THI RS13755
gene id: 426114:THI_RS13755
uniprot id: D6CM10
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS18190
gene id: 426114:THI_RS18190
uniprot id: D6CNE3
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

426114:THI RS00425
gene id: 426114:THI_RS00425
uniprot id: D6CKE0
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

426114:THI RS15140
gene id: 426114:THI_RS15140
uniprot id: D6CMV3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

426114:THI RS02175
gene id: 426114:THI_RS02175
uniprot id: D6CRG6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

426114:THI RS15205
gene id: 426114:THI_RS15205
uniprot id: D6CMW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

426114:THI RS00740
gene id: 426114:THI_RS00740
uniprot id: D6CQM7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

426114:THI RS16470
gene id: 426114:THI_RS16470
uniprot id: D6CNM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

426114:THI RS09835
gene id: 426114:THI_RS09835
uniprot id: D6CU31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

426114:THI RS15345
gene id: 426114:THI_RS15345
uniprot id: D6CMZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

426114:THI RS12500
gene id: 426114:THI_RS12500
uniprot id: D6CLA7
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

426114:THI RS13815
gene id: 426114:THI_RS13815
uniprot id: D6CM23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Periplasm
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

426114:THI RS16250
gene id: 426114:THI_RS16250
uniprot id: D6CNI0
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS05560
gene id: 426114:THI_RS05560
uniprot id: D6CPI2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

426114:THI RS04300
gene id: 426114:THI_RS04300
uniprot id: D6CSC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

426114:THI RS17790
gene id: 426114:THI_RS17790
uniprot id: D6CVT7
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

426114:THI RS02665
gene id: 426114:THI_RS02665
uniprot id: D6CRR9
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

426114:THI RS04350
gene id: 426114:THI_RS04350
uniprot id: D6CSD8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

426114:THI RS10515
gene id: 426114:THI_RS10515
uniprot id: D6CUG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

426114:THI RS03235
gene id: 426114:THI_RS03235
uniprot id: D6CS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

426114:THI RS13170
gene id: 426114:THI_RS13170
uniprot id: D6CLP1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

426114:THI RS10275
gene id: 426114:THI_RS10275
uniprot id: D6CUB6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

426114:THI RS00355
gene id: 426114:THI_RS00355
uniprot id: D6CPQ7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

426114:THI RS10035
gene id: 426114:THI_RS10035
uniprot id: D6CU71
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

426114:THI RS06905
gene id: 426114:THI_RS06905
uniprot id: D6CQC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

426114:THI RS06695
gene id: 426114:THI_RS06695
uniprot id: D6CQ79
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

426114:THI RS16490
gene id: 426114:THI_RS16490
uniprot id: D6CNN3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

426114:THI RS15095
gene id: 426114:THI_RS15095
uniprot id: D6CMU4
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

426114:THI RS14000
gene id: 426114:THI_RS14000
uniprot id: D6CM62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

426114:THI RS01335
gene id: 426114:THI_RS01335
uniprot id: D6CQZ8
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

426114:THI RS02375
gene id: 426114:THI_RS02375
uniprot id: D6CPQ7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

426114:THI RS05420
gene id: 426114:THI_RS05420
uniprot id: D6CPF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

426114:THI RS13675
gene id: 426114:THI_RS13675
uniprot id: D6CLZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

426114:THI RS02190
gene id: 426114:THI_RS02190
uniprot id: D6CRG9
names: Subunit
messages: Homodimer.

426114:THI RS01065
gene id: 426114:THI_RS01065
uniprot id: D6CQU2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

426114:THI RS12210
gene id: 426114:THI_RS12210
uniprot id: D6CVF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

426114:THI RS09350
gene id: 426114:THI_RS09350
uniprot id: D6CTT1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

426114:THI RS16090
gene id: 426114:THI_RS16090
uniprot id: D6CNE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

426114:THI RS00165
gene id: 426114:THI_RS00165
uniprot id: D6CVL6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

426114:THI RS15965
gene id: 426114:THI_RS15965
uniprot id: D6CNB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

426114:THI RS15635
gene id: 426114:THI_RS15635
uniprot id: D6CN53
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

426114:THI RS05665
gene id: 426114:THI_RS05665
uniprot id: D6CPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

426114:THI RS02915
gene id: 426114:THI_RS02915
uniprot id: D6CRX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

426114:THI RS13905
gene id: 426114:THI_RS13905
uniprot id: D6CM41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

426114:THI RS11170
gene id: 426114:THI_RS11170
uniprot id: D6CUU7
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

426114:THI RS15310
gene id: 426114:THI_RS15310
uniprot id: D6CMY7
names: Similarity
messages: Belongs to the GSP N family.

426114:THI RS02940
gene id: 426114:THI_RS02940
uniprot id: D6CRY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

426114:THI RS03500
gene id: 426114:THI_RS03500
uniprot id: D6CKM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

426114:THI RS04570
gene id: 426114:THI_RS04570
uniprot id: D6CSI3
names: Subcellular Location Annotation
messages: Membrane

426114:THI RS12145
gene id: 426114:THI_RS12145
uniprot id: D6CVE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

426114:THI RS09305
gene id: 426114:THI_RS09305
uniprot id: D6CTS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

426114:THI RS05680
gene id: 426114:THI_RS05680
uniprot id: D6CPK9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

426114:THI RS15625
gene id: 426114:THI_RS15625
uniprot id: D6CN51
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.