42514:derl2
gene id: 42514:derl2
uniprot id: A0A3B4E1F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108414240
gene id: 42514:LOC108414240
uniprot id: A0A3B4DIH0
names: Similarity
messages: Belongs to the beta-catenin family.

42514:cnksr2a
gene id: 42514:cnksr2a
uniprot id: A0A3B4C1A3
uniprot id: A0A3B4DTU5
names: Similarity
messages: Belongs to the CNKSR family.

42514:mars1
gene id: 42514:mars1
uniprot id: A0A3B4CHN4
uniprot id: A0A3B4E1G9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

42514:tgm1l1
gene id: 42514:tgm1l1
uniprot id: A0A3B4ENX7
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

42514:f13a1b
gene id: 42514:f13a1b
uniprot id: A0A3B4DC26
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

42514:abcc12
gene id: 42514:abcc12
uniprot id: A0A3B4D0D2
names: Subcellular Location Annotation
messages: Membrane

42514:tp53inp1
gene id: 42514:tp53inp1
uniprot id: A0A3B4EEN9
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

42514:LOC108437938
gene id: 42514:LOC108437938
uniprot id: A0A3B4CFT1
names: Similarity
messages: Belongs to the aldo/keto reductase family.

42514:LOC108440498
gene id: 42514:LOC108440498
uniprot id: A0A3B4D938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:chrna5
gene id: 42514:chrna5
uniprot id: A0A3B4DDS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:dnttip2
gene id: 42514:dnttip2
uniprot id: A0A3B4E597
names: Subcellular Location Annotation
messages: nucleolus

42514:chl1b
gene id: 42514:chl1b
uniprot id: A0A3B4CU50
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

42514:actr8
gene id: 42514:actr8
uniprot id: A0A3B4BZE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

42514:fgfbp1b
gene id: 42514:fgfbp1b
uniprot id: A0A3B4BS76
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

42514:LOC108432375
gene id: 42514:LOC108432375
uniprot id: A0A3B4DWL3
names: Subcellular Location Annotation
messages: Membrane

42514:rheb
gene id: 42514:rheb
uniprot id: A0A3B4D6F6
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:dscc1
gene id: 42514:dscc1
uniprot id: A0A3B4BKS3
names: Similarity
messages: Belongs to the DCC1 family.

42514:mtx3
gene id: 42514:mtx3
uniprot id: A0A3B4ENL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:msh3
gene id: 42514:msh3
uniprot id: A0A3B4DF10
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

42514:LOC108433286
gene id: 42514:LOC108433286
uniprot id: A0A3B4EKP0
names: Similarity
messages: Belongs to the FAM168 family.

42514:golm1
gene id: 42514:golm1
uniprot id: A0A3B4CK20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

42514:pde3a
gene id: 42514:pde3a
uniprot id: A0A3B4CXD0
uniprot id: A0A3B4EDU0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:LOC108424884
gene id: 42514:LOC108424884
uniprot id: A0A3B4D5P1
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

42514:hmgcl
gene id: 42514:hmgcl
uniprot id: A0A3B4D310
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

42514:dmbx1b
gene id: 42514:dmbx1b
uniprot id: A0A3B4C5U5
names: Subcellular Location Annotation
messages: Nucleus

42514:gucy1b1
gene id: 42514:gucy1b1
uniprot id: A0A3B4BPL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

42514:ncdn
gene id: 42514:ncdn
uniprot id: A0A3B4EHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

42514:ror2
gene id: 42514:ror2
uniprot id: A0A3B4CRZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:lipf
gene id: 42514:lipf
uniprot id: A0A3B4DN44
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

42514:txndc5
gene id: 42514:txndc5
uniprot id: A0A3B4D6E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

42514:plk4
gene id: 42514:plk4
uniprot id: A0A3B4CMZ1
names: Subcellular Location Annotation
messages: centriole

42514:axin1
gene id: 42514:axin1
uniprot id: A0A3B4C1L0
uniprot id: A0A3B4DQJ5
names: Subcellular Location Annotation
messages: Cytoplasm

42514:b4galnt1b
gene id: 42514:b4galnt1b
uniprot id: A0A3B4DYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:nfe2
gene id: 42514:nfe2
uniprot id: A0A3B4E9F9
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

42514:LOC108438085
gene id: 42514:LOC108438085
uniprot id: A0A3B4DQ72
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

42514:atp6v1c1b
gene id: 42514:atp6v1c1b
uniprot id: A0A3B4C4C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

42514:si:dkey-205h23.2
gene id: 42514:si:dkey-205h23.2
uniprot id: A0A3B4DHB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

42514:ptges3b
gene id: 42514:ptges3b
uniprot id: A0A3B4C0C7
names: Similarity
messages: Belongs to the p23/wos2 family.

42514:borcs8
gene id: 42514:borcs8
uniprot id: A0A3B4CS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS8 family.
messages: Lysosome membrane
messages: Membrane

42514:slc39a4
gene id: 42514:slc39a4
uniprot id: A0A3B4E4D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

42514:palm1a
gene id: 42514:palm1a
uniprot id: A0A3B4D401
uniprot id: A0A3B4D515
uniprot id: A0A3B4EGU4
names: Similarity
messages: Belongs to the paralemmin family.

42514:LOC108438288
gene id: 42514:LOC108438288
uniprot id: A0A3B4D9R7
uniprot id: A0A3B4EL36
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108425339
gene id: 42514:LOC108425339
uniprot id: A0A3B4BQP5
uniprot id: A0A3B4DJ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

42514:leo1
gene id: 42514:leo1
uniprot id: A0A3B4CZD5
names: Similarity
messages: Belongs to the LEO1 family.

42514:arpc4l
gene id: 42514:arpc4l
uniprot id: A0A3B4CCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

42514:atp10b
gene id: 42514:atp10b
uniprot id: A0A3B4D0W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

42514:slc5a6a
gene id: 42514:slc5a6a
uniprot id: A0A3B4DAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:LOC108412547
gene id: 42514:LOC108412547
uniprot id: A0A3B4DGS1
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:LOC108412090
gene id: 42514:LOC108412090
uniprot id: A0A3B4CYV1
uniprot id: A0A3B4EB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:LOC108444057
gene id: 42514:LOC108444057
uniprot id: A0A3B4EG13
names: Similarity
messages: Belongs to the methyltransferase superfamily.

42514:dtx4b
gene id: 42514:dtx4b
uniprot id: A0A3B4DUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

42514:myo1d
gene id: 42514:myo1d
uniprot id: A0A3B4BQ29
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:LOC108443059
gene id: 42514:LOC108443059
uniprot id: A0A3B4C5U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:LOC108430517
gene id: 42514:LOC108430517
uniprot id: A0A3B4D5Y3
names: Similarity
messages: Belongs to the importin alpha family.

42514:slc47a3
gene id: 42514:slc47a3
uniprot id: A0A3B4BTR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

42514:kdm2ab
gene id: 42514:kdm2ab
uniprot id: A0A3B4D7G9
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

42514:valopa
gene id: 42514:valopa
uniprot id: A0A3B4DRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

42514:ehd3
gene id: 42514:ehd3
uniprot id: A0A3B4DFE5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

42514:adka
gene id: 42514:adka
uniprot id: A0A3B4CB61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

42514:mtch2
gene id: 42514:mtch2
uniprot id: A0A3B4D1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:pou6f1
gene id: 42514:pou6f1
uniprot id: A0A3B4CZK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

42514:mrps25
gene id: 42514:mrps25
uniprot id: A0A3B4BNP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

42514:bves
gene id: 42514:bves
uniprot id: A0A3B4E373
names: Similarity
messages: Belongs to the popeye family.

42514:cflara
gene id: 42514:cflara
uniprot id: A0A3B4DIF7
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:slc43a3a
gene id: 42514:slc43a3a
uniprot id: A0A3B4CFA4
names: Subcellular Location Annotation
messages: Membrane

42514:cltcb
gene id: 42514:cltcb
uniprot id: A0A3B4D4U2
uniprot id: A0A3B4EGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

42514:ss18l2
gene id: 42514:ss18l2
uniprot id: A0A3B4EI25
names: Similarity
messages: Belongs to the SS18 family.

42514:tmprss4a
gene id: 42514:tmprss4a
uniprot id: A0A3B4D1J7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108424318
gene id: 42514:LOC108424318
uniprot id: A0A3B4D1G3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

42514:si:dkey-103j14.5
gene id: 42514:si:dkey-103j14.5
uniprot id: A0A3B4DMF5
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

42514:maml1
gene id: 42514:maml1
uniprot id: A0A3B4E8L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

42514:LOC108414591
gene id: 42514:LOC108414591
uniprot id: A0A3B4ECH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:LOC108429239
gene id: 42514:LOC108429239
uniprot id: A0A3B4C4Y9
names: Similarity
messages: Belongs to the peptidase C13 family.

42514:nt5c2l1
gene id: 42514:nt5c2l1
uniprot id: A0A3B4BVX7
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

42514:elovl1a
gene id: 42514:elovl1a
uniprot id: A0A3B4D3C1
uniprot id: A0A3B4EGU3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

42514:runx1
gene id: 42514:runx1
uniprot id: A0A3B4BY88
uniprot id: A0A3B4BYH5
uniprot id: A0A3B4DL02
names: Subcellular Location Annotation
messages: Nucleus

42514:plac8.2
gene id: 42514:plac8.2
uniprot id: A0A3B4DLH8
names: Similarity
messages: Belongs to the cornifelin family.

42514:ildr1b
gene id: 42514:ildr1b
uniprot id: A0A3B4D2F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

42514:gtdc1
gene id: 42514:gtdc1
uniprot id: A0A3B4DVR2
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

42514:aup1
gene id: 42514:aup1
uniprot id: A0A3B4DBH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AUP1 family.
messages: Membrane

42514:si:ch73-12o23.1
gene id: 42514:si:ch73-12o23.1
uniprot id: A0A3B4C776
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:manbal
gene id: 42514:manbal
uniprot id: A0A3B4D8A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

42514:LOC108436734
gene id: 42514:LOC108436734
uniprot id: A0A3B4DM37
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:LOC108429232
gene id: 42514:LOC108429232
uniprot id: A0A3B4DTG6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:si:dkey-117i10.1
gene id: 42514:si:dkey-117i10.1
uniprot id: A0A3B4BSQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

42514:si:ch73-206p6.1
gene id: 42514:si:ch73-206p6.1
uniprot id: A0A3B4DGH2
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

42514:LOC108417215
gene id: 42514:LOC108417215
uniprot id: A0A3B4DS60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:tango6
gene id: 42514:tango6
uniprot id: A0A3B4E4Z5
names: Similarity
messages: Belongs to the Tango6 family.

42514:fut10
gene id: 42514:fut10
uniprot id: A0A3B4ED14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

42514:LOC108434414
gene id: 42514:LOC108434414
uniprot id: A0A3B4DDF8
names: Similarity
messages: Belongs to the DOCK family.

42514:sec61b
gene id: 42514:sec61b
uniprot id: A0A3B4EIR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

42514:sec24d
gene id: 42514:sec24d
uniprot id: A0A3B4DR03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

42514:grin3bb
gene id: 42514:grin3bb
uniprot id: A0A3B4EIN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:chico
gene id: 42514:chico
uniprot id: A0A3B4EFC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

42514:pdgfbb
gene id: 42514:pdgfbb
uniprot id: A0A3B4CC57
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

42514:slc27a2a
gene id: 42514:slc27a2a
uniprot id: A0A3B4DQT7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:l1camb
gene id: 42514:l1camb
uniprot id: A0A3B4DNG1
uniprot id: A0A3B4DQY8
uniprot id: A0A3B4DR28
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

42514:vopp1
gene id: 42514:vopp1
uniprot id: A0A3B4BT19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

42514:grem1a
gene id: 42514:grem1a
uniprot id: A0A3B4ECN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

42514:pdcd4b
gene id: 42514:pdcd4b
uniprot id: A0A3B4CKN9
names: Similarity
messages: Belongs to the PDCD4 family.

42514:sec22bb
gene id: 42514:sec22bb
uniprot id: A0A3B4D4D2
uniprot id: A0A3B4EEX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

42514:ube2l3a
gene id: 42514:ube2l3a
uniprot id: A0A3B4C5H1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:hat1
gene id: 42514:hat1
uniprot id: A0A3B4CSB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

42514:gnrh2
gene id: 42514:gnrh2
uniprot id: A0A3B4E158
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins.

42514:egfra
gene id: 42514:egfra
uniprot id: A0A3B4DUA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

42514:adra1aa
gene id: 42514:adra1aa
uniprot id: A0A3B4BRC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:carmil2
gene id: 42514:carmil2
uniprot id: A0A3B4E564
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

42514:ptgdsa
gene id: 42514:ptgdsa
uniprot id: A0A3B4CL01
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

42514:LOC108432685
gene id: 42514:LOC108432685
uniprot id: A0A3B4DJ11
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:tyk2
gene id: 42514:tyk2
uniprot id: A0A3B4CFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

42514:myoz2a
gene id: 42514:myoz2a
uniprot id: A0A3B4DR27
names: Similarity
messages: Belongs to the myozenin family.

42514:LOC108411917
gene id: 42514:LOC108411917
uniprot id: A0A3B4C511
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

42514:cryba4
gene id: 42514:cryba4
uniprot id: A0A3B4BW09
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:ccnb2
gene id: 42514:ccnb2
uniprot id: A0A3B4CT40
names: Similarity
messages: Belongs to the cyclin family.

42514:htr4
gene id: 42514:htr4
uniprot id: A0A3B4D2I1
uniprot id: A0A3B4EFZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

42514:psma8
gene id: 42514:psma8
uniprot id: A0A3B4DC36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

42514:prkcba
gene id: 42514:prkcba
uniprot id: A0A3B4DZF2
uniprot id: A0A3B4DZG7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

42514:sept3
gene id: 42514:sept3
uniprot id: A0A3B4D166
uniprot id: A0A3B4D184
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

42514:znf687a
gene id: 42514:znf687a
uniprot id: A0A3B4CU10
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

42514:LOC108424060
gene id: 42514:LOC108424060
uniprot id: A0A3B4BXF7
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:rusf1
gene id: 42514:rusf1
uniprot id: A0A3B4DYG7
names: Similarity
messages: Belongs to the RUS1 family.

42514:mmd
gene id: 42514:mmd
uniprot id: A0A3B4CP77
uniprot id: A0A3B4E3L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:gata4
gene id: 42514:gata4
uniprot id: A0A3B4BM25
names: Subcellular Location Annotation
messages: Nucleus

42514:arrdc1b
gene id: 42514:arrdc1b
uniprot id: A0A3B4EGK6
names: Similarity
messages: Belongs to the arrestin family.

42514:ppp2r5a
gene id: 42514:ppp2r5a
uniprot id: A0A3B4C2I0
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

42514:sumf1
gene id: 42514:sumf1
uniprot id: A0A3B4CED5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

42514:cd151
gene id: 42514:cd151
uniprot id: A0A3B4BXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:icmt
gene id: 42514:icmt
uniprot id: A0A3B4E3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:nek7
gene id: 42514:nek7
uniprot id: A0A3B4C8K6
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:nudt15
gene id: 42514:nudt15
uniprot id: A0A3B4CQJ0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

42514:lamtor2
gene id: 42514:lamtor2
uniprot id: A0A3B4DEC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

42514:eif4h
gene id: 42514:eif4h
uniprot id: A0A3B4C0J3
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

42514:cxcl19
gene id: 42514:cxcl19
uniprot id: A0A3B4CTE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

42514:rab38b
gene id: 42514:rab38b
uniprot id: A0A3B4E1Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

42514:gmfg
gene id: 42514:gmfg
uniprot id: A0A3B4CDX1
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

42514:tmem144b
gene id: 42514:tmem144b
uniprot id: A0A3B4EA33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

42514:myg1
gene id: 42514:myg1
uniprot id: A0A3B4BX34
names: Similarity
messages: Belongs to the MYG1 family.

42514:nr0b2a
gene id: 42514:nr0b2a
uniprot id: A0A3B4EM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

42514:LOC108427298
gene id: 42514:LOC108427298
uniprot id: A0A3B4CQ99
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:LOC108424654
gene id: 42514:LOC108424654
uniprot id: A0A3B4DHF2
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

42514:si:dkey-148a17.6
gene id: 42514:si:dkey-148a17.6
uniprot id: A0A3B4DWX8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:araf
gene id: 42514:araf
uniprot id: A0A3B4BW13
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

42514:galnt2
gene id: 42514:galnt2
uniprot id: A0A3B4CDW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:phospho2
gene id: 42514:phospho2
uniprot id: A0A3B4C3U9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

42514:gna11b
gene id: 42514:gna11b
uniprot id: A0A3B4CZ94
uniprot id: A0A3B4EF82
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

42514:arl11
gene id: 42514:arl11
uniprot id: A0A3B4D5M6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

42514:zgc:174164
gene id: 42514:zgc:174164
uniprot id: A0A3B4EJN6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:psph
gene id: 42514:psph
uniprot id: A0A3B4EQ84
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

42514:itga7
gene id: 42514:itga7
uniprot id: A0A3B4DES7
uniprot id: A0A3B4DIG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

42514:hck
gene id: 42514:hck
uniprot id: A0A3B4BT50
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:mmp25a
gene id: 42514:mmp25a
uniprot id: A0A3B4E8D9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

42514:LOC108432803
gene id: 42514:LOC108432803
uniprot id: A0A3B4CYE2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:cpsf2
gene id: 42514:cpsf2
uniprot id: A0A3B4C0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

42514:gja10b
gene id: 42514:gja10b
uniprot id: A0A3B4C538
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:LOC108410710
gene id: 42514:LOC108410710
uniprot id: A0A3B4E0M4
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

42514:vapal
gene id: 42514:vapal
uniprot id: A0A3B4D5C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108437644
gene id: 42514:LOC108437644
uniprot id: A0A3B4BY08
uniprot id: A0A3B4DND6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

42514:smg1
gene id: 42514:smg1
uniprot id: A0A3B4CSL3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

42514:st7l
gene id: 42514:st7l
uniprot id: A0A3B4DNF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

42514:xrn2
gene id: 42514:xrn2
uniprot id: A0A3B4C115
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

42514:grk7b
gene id: 42514:grk7b
uniprot id: A0A3B4EN25
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

42514:sypl1
gene id: 42514:sypl1
uniprot id: A0A3B4D4R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

42514:parp9
gene id: 42514:parp9
uniprot id: A0A3B4ENW4
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:gba3
gene id: 42514:gba3
uniprot id: A0A3B4BZN9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

42514:dot1l
gene id: 42514:dot1l
uniprot id: A0A3B4DB43
uniprot id: A0A3B4EPY8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

42514:LOC108438907
gene id: 42514:LOC108438907
uniprot id: A0A3B4EDK8
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:plpp2b
gene id: 42514:plpp2b
uniprot id: A0A3B4E7C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:colgalt1a
gene id: 42514:colgalt1a
uniprot id: A0A3B4CDM2
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

42514:hip1
gene id: 42514:hip1
uniprot id: A0A3B4BT66
names: Similarity
messages: Belongs to the SLA2 family.

42514:eno1b
gene id: 42514:eno1b
uniprot id: A0A3B4CGS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

42514:LOC108441957
gene id: 42514:LOC108441957
uniprot id: A0A3B4DSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:krtcap2
gene id: 42514:krtcap2
uniprot id: A0A3B4ENB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

42514:cryabb
gene id: 42514:cryabb
uniprot id: A0A3B4CB64
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

42514:ivd
gene id: 42514:ivd
uniprot id: A0A3B4CVP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

42514:tmem150c
gene id: 42514:tmem150c
uniprot id: A0A3B4E2J0
names: Subcellular Location Annotation
messages: Membrane

42514:midn
gene id: 42514:midn
uniprot id: A0A3B4CPQ5
names: Subcellular Location Annotation
messages: Nucleus

42514:brinp3a.2
gene id: 42514:brinp3a.2
uniprot id: A0A3B4C2V6
names: Similarity
messages: Belongs to the BRINP family.

42514:nipa2
gene id: 42514:nipa2
uniprot id: A0A3B4C6B0
uniprot id: A0A3B4DVF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

42514:LOC108432353
gene id: 42514:LOC108432353
uniprot id: A0A3B4CP78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

42514:tbk1
gene id: 42514:tbk1
uniprot id: A0A3B4DA98
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108429390
gene id: 42514:LOC108429390
uniprot id: A0A3B4EK70
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

42514:ndufs1
gene id: 42514:ndufs1
uniprot id: A0A3B4BS38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

42514:sdr16c5a
gene id: 42514:sdr16c5a
uniprot id: A0A3B4EPP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:gcgrb
gene id: 42514:gcgrb
uniprot id: A0A3B4C7K0
names: Subcellular Location Annotation
messages: Membrane

42514:map2k4a
gene id: 42514:map2k4a
uniprot id: A0A3B4CQG9
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:cd248a
gene id: 42514:cd248a
uniprot id: A0A3B4C5L0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:pa2g4b
gene id: 42514:pa2g4b
uniprot id: A0A3B4CUS1
names: Similarity
messages: Belongs to the peptidase M24 family.

42514:prpf38a
gene id: 42514:prpf38a
uniprot id: A0A3B4DQY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

42514:ror1
gene id: 42514:ror1
uniprot id: A0A3B4DK10
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:mffb
gene id: 42514:mffb
uniprot id: A0A3B4EL06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

42514:gtf2h1
gene id: 42514:gtf2h1
uniprot id: A0A3B4EF56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

42514:march9
gene id: 42514:march9
uniprot id: A0A3B4CX45
names: Subcellular Location Annotation
messages: Membrane

42514:yju2
gene id: 42514:yju2
uniprot id: A0A3B4D3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

42514:ppa1b
gene id: 42514:ppa1b
uniprot id: A0A3B4BRE2
names: Similarity
messages: Belongs to the PPase family.

42514:c8a
gene id: 42514:c8a
uniprot id: A0A3B4BYU7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:LOC108428399
gene id: 42514:LOC108428399
uniprot id: A0A3B4E7D4
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

42514:ramp2
gene id: 42514:ramp2
uniprot id: A0A3B4E2X4
names: Similarity
messages: Belongs to the RAMP family.

42514:sh3rf1
gene id: 42514:sh3rf1
uniprot id: A0A3B4CD96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

42514:LOC108427927
gene id: 42514:LOC108427927
uniprot id: A0A3B4CBJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

42514:podxl
gene id: 42514:podxl
uniprot id: A0A3B4DHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the podocalyxin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: filopodium
messages: lamellipodium
messages: microvillus
messages: ruffle

42514:LOC108433575
gene id: 42514:LOC108433575
uniprot id: A0A3B4E3A4
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:LOC108429167
gene id: 42514:LOC108429167
uniprot id: A0A3B4DV84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

42514:tcn2
gene id: 42514:tcn2
uniprot id: A0A3B4C078
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

42514:ipo4
gene id: 42514:ipo4
uniprot id: A0A3B4DBK1
names: Subcellular Location Annotation
messages: Cytoplasm

42514:phf10
gene id: 42514:phf10
uniprot id: A0A3B4C4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

42514:lmod3
gene id: 42514:lmod3
uniprot id: A0A3B4CST8
names: Subcellular Location Annotation
messages: cytoskeleton

42514:rab39bb
gene id: 42514:rab39bb
uniprot id: A0A3B4C8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

42514:cetn4
gene id: 42514:cetn4
uniprot id: A0A3B4DAF5
names: Similarity
messages: Belongs to the centrin family.

42514:glo1
gene id: 42514:glo1
uniprot id: A0A3B4CGB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

42514:kat8
gene id: 42514:kat8
uniprot id: A0A3B4E4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

42514:LOC108411971
gene id: 42514:LOC108411971
uniprot id: A0A3B4C1K5
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

42514:cenpx
gene id: 42514:cenpx
uniprot id: A0A3B4D0T2
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

42514:cltrn
gene id: 42514:cltrn
uniprot id: A0A3B4D531
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:slc2a8
gene id: 42514:slc2a8
uniprot id: A0A3B4DAU0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:ahcyl1
gene id: 42514:ahcyl1
uniprot id: A0A3B4BPR1
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

42514:LOC108438305
gene id: 42514:LOC108438305
uniprot id: A0A3B4D4R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

42514:hspb8
gene id: 42514:hspb8
uniprot id: A0A3B4BZI6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

42514:psmf1
gene id: 42514:psmf1
uniprot id: A0A3B4DWR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

42514:LOC108437129
gene id: 42514:LOC108437129
uniprot id: A0A3B4BWS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:adgra1a
gene id: 42514:adgra1a
uniprot id: A0A3B4BSB2
names: Subcellular Location Annotation
messages: Membrane

42514:hlx1
gene id: 42514:hlx1
uniprot id: A0A3B4BVY7
names: Subcellular Location Annotation
messages: Nucleus

42514:anxa1a
gene id: 42514:anxa1a
uniprot id: A0A3B4BT83
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium

42514:pla2g4aa
gene id: 42514:pla2g4aa
uniprot id: A0A3B4CMG8
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

42514:kcnc3a
gene id: 42514:kcnc3a
uniprot id: A0A3B4CIK1
uniprot id: A0A3B4CKE0
uniprot id: A0A3B4CLT7
names: Subcellular Location Annotation
messages: Membrane

42514:idi1
gene id: 42514:idi1
uniprot id: A0A3B4DDZ2
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

42514:tram2
gene id: 42514:tram2
uniprot id: A0A3B4DWG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

42514:LOC108439064
gene id: 42514:LOC108439064
uniprot id: A0A3B4E4P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: trans-Golgi network

42514:slco2b1
gene id: 42514:slco2b1
uniprot id: A0A3B4DZQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

42514:mgat1b
gene id: 42514:mgat1b
uniprot id: A0A3B4D9B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

42514:tfe3a
gene id: 42514:tfe3a
uniprot id: A0A3B4EIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

42514:hmbox1a
gene id: 42514:hmbox1a
uniprot id: A0A3B4D7Z6
names: Subcellular Location Annotation
messages: Nucleus

42514:tpm4b
gene id: 42514:tpm4b
uniprot id: A0A3B4D2M7
uniprot id: A0A3B4D567
uniprot id: A0A3B4EH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

42514:tmem198a
gene id: 42514:tmem198a
uniprot id: A0A3B4C639
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

42514:avpr1aa
gene id: 42514:avpr1aa
uniprot id: A0A3B4D679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:smpd5
gene id: 42514:smpd5
uniprot id: A0A3B4E6G9
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

42514:LOC108424260
gene id: 42514:LOC108424260
uniprot id: A0A3B4EFQ5
names: Subcellular Location Annotation
messages: Membrane

42514:rab42a
gene id: 42514:rab42a
uniprot id: A0A3B4E312
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

42514:aurkaip1
gene id: 42514:aurkaip1
uniprot id: A0A3B4EDA3
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

42514:tmem145
gene id: 42514:tmem145
uniprot id: A0A3B4ELI0
names: Subcellular Location Annotation
messages: Membrane

42514:kynu
gene id: 42514:kynu
uniprot id: A0A3B4EFD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.

42514:sema4e
gene id: 42514:sema4e
uniprot id: A0A3B4DUL8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:copb2
gene id: 42514:copb2
uniprot id: A0A3B4D348
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

42514:gria2b
gene id: 42514:gria2b
uniprot id: A0A3B4CDY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:rtn1a
gene id: 42514:rtn1a
uniprot id: A0A3B4C0H6
uniprot id: A0A3B4DQ52
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108439786
gene id: 42514:LOC108439786
uniprot id: A0A3B4DP49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:lamtor5
gene id: 42514:lamtor5
uniprot id: A0A3B4DIL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR5 family.
messages: Lysosome

42514:xpnpep1
gene id: 42514:xpnpep1
uniprot id: A0A3B4CJX0
uniprot id: A0A3B4E2Z5
names: Similarity
messages: Belongs to the peptidase M24B family.

42514:si:dkeyp-82a1.6
gene id: 42514:si:dkeyp-82a1.6
uniprot id: A0A3B4D0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

42514:LOC108434337
gene id: 42514:LOC108434337
uniprot id: A0A3B4DKT3
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

42514:adra1ab
gene id: 42514:adra1ab
uniprot id: A0A3B4D2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:clcn4
gene id: 42514:clcn4
uniprot id: A0A3B4BPE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

42514:desmb
gene id: 42514:desmb
uniprot id: A0A3B4EA97
names: Similarity
messages: Belongs to the intermediate filament family.

42514:cmc4
gene id: 42514:cmc4
uniprot id: A0A3B4EHZ6
names: Similarity
messages: Belongs to the CMC4 family.

42514:tctn1
gene id: 42514:tctn1
uniprot id: A0A3B4BVI0
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

42514:gdpd5a
gene id: 42514:gdpd5a
uniprot id: A0A3B4CCT2
uniprot id: A0A3B4DZD5
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

42514:ptpn4a
gene id: 42514:ptpn4a
uniprot id: A0A3B4D807
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

42514:erfl3
gene id: 42514:erfl3
uniprot id: A0A3B4CVA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:bbox1
gene id: 42514:bbox1
uniprot id: A0A3B4C9W6
names: Function
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.

42514:rrm2b
gene id: 42514:rrm2b
uniprot id: A0A3B4DS93
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

42514:cav3
gene id: 42514:cav3
uniprot id: A0A3B4CJ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

42514:LOC108439880
gene id: 42514:LOC108439880
uniprot id: A0A3B4D9D7
names: Similarity
messages: Belongs to the TGF-beta family.

42514:zgc:92162
gene id: 42514:zgc:92162
uniprot id: A0A3B4BXV1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

42514:tmem177
gene id: 42514:tmem177
uniprot id: A0A3B4D9I5
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

42514:zdhhc24
gene id: 42514:zdhhc24
uniprot id: A0A3B4E7K9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:lbx2
gene id: 42514:lbx2
uniprot id: A0A3B4D7L1
names: Subcellular Location Annotation
messages: Nucleus

42514:pdca
gene id: 42514:pdca
uniprot id: A0A3B4CS50
names: Similarity
messages: Belongs to the phosducin family.

42514:dpysl2b
gene id: 42514:dpysl2b
uniprot id: A0A3B4D0R7
uniprot id: A0A3B4D2P0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

42514:miga2
gene id: 42514:miga2
uniprot id: A0A3B4CGX7
names: Similarity
messages: Belongs to the mitoguardin family.

42514:man2c1
gene id: 42514:man2c1
uniprot id: A0A3B4C891
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

42514:hoxc12a
gene id: 42514:hoxc12a
uniprot id: A0A3B4EB15
names: Subcellular Location Annotation
messages: Nucleus

42514:tcea2
gene id: 42514:tcea2
uniprot id: A0A3B4E3L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

42514:pan2
gene id: 42514:pan2
uniprot id: A0A3B4DB98
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

42514:afg3l2
gene id: 42514:afg3l2
uniprot id: A0A3B4DDL4
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

42514:gpx7
gene id: 42514:gpx7
uniprot id: A0A3B4CZ61
names: Similarity
messages: Belongs to the glutathione peroxidase family.

42514:srpra
gene id: 42514:srpra
uniprot id: A0A3B4DWR2
uniprot id: A0A3B4DY66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:ggh
gene id: 42514:ggh
uniprot id: A0A3B4EBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

42514:plrg1
gene id: 42514:plrg1
uniprot id: A0A3B4CTZ8
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

42514:gabrd
gene id: 42514:gabrd
uniprot id: A0A3B4DSN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:ctbs
gene id: 42514:ctbs
uniprot id: A0A3B4E2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Lysosome

42514:prdm4
gene id: 42514:prdm4
uniprot id: A0A3B4CHE0
names: Subcellular Location Annotation
messages: Nucleus

42514:map2k2a
gene id: 42514:map2k2a
uniprot id: A0A3B4E4L6
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:fam171a2a
gene id: 42514:fam171a2a
uniprot id: A0A3B4CAZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

42514:gpr37b
gene id: 42514:gpr37b
uniprot id: A0A3B4D8C6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:slbp2
gene id: 42514:slbp2
uniprot id: A0A3B4C7Z0
names: Similarity
messages: Belongs to the SLBP family.

42514:runx2a
gene id: 42514:runx2a
uniprot id: A0A3B4CSK6
uniprot id: A0A3B4E7Y7
names: Subcellular Location Annotation
messages: Nucleus

42514:ypel2b
gene id: 42514:ypel2b
uniprot id: A0A3B4DM28
names: Similarity
messages: Belongs to the yippee family.

42514:tfr1b
gene id: 42514:tfr1b
uniprot id: A0A3B4BTA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

42514:slc26a2
gene id: 42514:slc26a2
uniprot id: A0A3B4D2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sulfate transporter which mediates sulfate uptake into chondrocytes in order to maintain adequate sulfation of proteoglycans which is needed for cartilage development. Mediates electroneutral anion exchange of sulfate ions for oxalate ions, sulfate and oxalate ions for chloride and/or hydroxyl ions and chloride ions for bromide, iodide and nitrate ions. The coupling of sulfate transport to both hydroxyl and chloride ions likely serves to ensure transport at both acidic pH when most sulfate uptake is mediated by sulfate-hydroxide exchange and alkaline pH when most sulfate uptake is mediated by sulfate-chloride exchange. Essential for chondrocyte proliferation, differentiation and cell size expansion.

42514:sult5a1
gene id: 42514:sult5a1
uniprot id: A0A3B4C3D3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:shrprbck1r
gene id: 42514:shrprbck1r
uniprot id: A0A3B4DIN6
names: Similarity
messages: Belongs to the RBR family.

42514:LOC108443230
gene id: 42514:LOC108443230
uniprot id: A0A3B4DK04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:casp10
gene id: 42514:casp10
uniprot id: A0A3B4CX19
uniprot id: A0A3B4CZE3
uniprot id: A0A3B4EC34
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:pclaf
gene id: 42514:pclaf
uniprot id: A0A3B4E1T0
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

42514:ppp5c
gene id: 42514:ppp5c
uniprot id: A0A3B4BTC9
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

42514:sars1
gene id: 42514:sars1
uniprot id: A0A3B4EEW0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

42514:fis1
gene id: 42514:fis1
uniprot id: A0A3B4E7E1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

42514:LOC108435734
gene id: 42514:LOC108435734
uniprot id: A0A3B4E6P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

42514:coq9
gene id: 42514:coq9
uniprot id: A0A3B4DUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

42514:rell1
gene id: 42514:rell1
uniprot id: A0A3B4BYQ7
names: Similarity
messages: Belongs to the RELT family.

42514:vwc2
gene id: 42514:vwc2
uniprot id: A0A3B4EQN7
names: Subcellular Location Annotation
messages: Synapse

42514:rbp2a
gene id: 42514:rbp2a
uniprot id: A0A3B4CYZ7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:clic5b
gene id: 42514:clic5b
uniprot id: A0A3B4CL28
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

42514:LOC108425541
gene id: 42514:LOC108425541
uniprot id: A0A3B4CUC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

42514:LOC108412783
gene id: 42514:LOC108412783
uniprot id: A0A3B4CZ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

42514:kras
gene id: 42514:kras
uniprot id: A0A3B4DF28
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:anxa13l
gene id: 42514:anxa13l
uniprot id: A0A3B4E3N6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

42514:LOC108427756
gene id: 42514:LOC108427756
uniprot id: A0A3B4D3Y7
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

42514:iscu
gene id: 42514:iscu
uniprot id: A0A3B4C0Y8
names: Similarity
messages: Belongs to the NifU family.

42514:rps3
gene id: 42514:rps3
uniprot id: A0A3B4E7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: spindle

42514:slc12a4
gene id: 42514:slc12a4
uniprot id: A0A3B4EHW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:nipblb
gene id: 42514:nipblb
uniprot id: A0A3B4CC63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

42514:aldh7a1
gene id: 42514:aldh7a1
uniprot id: A0A3B4DK63
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

42514:il17ra1a
gene id: 42514:il17ra1a
uniprot id: A0A3B4BUX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:cited1
gene id: 42514:cited1
uniprot id: A0A3B4BWG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

42514:adcyap1r1a
gene id: 42514:adcyap1r1a
uniprot id: A0A3B4C9K2
uniprot id: A0A3B4DWW1
names: Subcellular Location Annotation
messages: Membrane

42514:grm5b
gene id: 42514:grm5b
uniprot id: A0A3B4DAM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

42514:polr2i
gene id: 42514:polr2i
uniprot id: A0A3B4EJP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

42514:fam163ba
gene id: 42514:fam163ba
uniprot id: A0A3B4CL78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

42514:LOC108425804
gene id: 42514:LOC108425804
uniprot id: A0A3B4BNG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

42514:myh9b
gene id: 42514:myh9b
uniprot id: A0A3B4C917
uniprot id: A0A3B4C945
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:rab39ba
gene id: 42514:rab39ba
uniprot id: A0A3B4DZ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

42514:LOC108411237
gene id: 42514:LOC108411237
uniprot id: A0A3B4C8X7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

42514:dph2
gene id: 42514:dph2
uniprot id: A0A3B4CQW2
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

42514:clcc1
gene id: 42514:clcc1
uniprot id: A0A3B4CDE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel MCLC family.
messages: Membrane

42514:samm50l
gene id: 42514:samm50l
uniprot id: A0A3B4C0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

42514:map3k10
gene id: 42514:map3k10
uniprot id: A0A3B4CRQ1
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

42514:snf8
gene id: 42514:snf8
uniprot id: A0A3B4C9P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

42514:zgc:110158
gene id: 42514:zgc:110158
uniprot id: A0A3B4D6P5
uniprot id: A0A3B4EHY0
names: Subcellular Location Annotation
messages: Nucleus

42514:ppp1r14c
gene id: 42514:ppp1r14c
uniprot id: A0A3B4CYT6
names: Similarity
messages: Belongs to the PP1 inhibitor family.

42514:hirip3
gene id: 42514:hirip3
uniprot id: A0A3B4CPJ2
names: Subcellular Location Annotation
messages: Nucleus

42514:opn3
gene id: 42514:opn3
uniprot id: A0A3B4BSZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

42514:prokr1b
gene id: 42514:prokr1b
uniprot id: A0A3B4D6Q9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:hnf1bb
gene id: 42514:hnf1bb
uniprot id: A0A3B4CAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

42514:rpgrip1l
gene id: 42514:rpgrip1l
uniprot id: A0A3B4DI81
names: Similarity
messages: Belongs to the RPGRIP1 family.

42514:pde9a
gene id: 42514:pde9a
uniprot id: A0A3B4CG24
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:slc7a1b
gene id: 42514:slc7a1b
uniprot id: A0A3B4BZ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

42514:sept8a
gene id: 42514:sept8a
uniprot id: A0A3B4D985
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

42514:nlk2
gene id: 42514:nlk2
uniprot id: A0A3B4CFJ1
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

42514:sf3b1
gene id: 42514:sf3b1
uniprot id: A0A3B4BSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

42514:LOC108410422
gene id: 42514:LOC108410422
uniprot id: A0A3B4EG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:LOC108423896
gene id: 42514:LOC108423896
uniprot id: A0A3B4E2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:parp1
gene id: 42514:parp1
uniprot id: A0A3B4CA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

42514:pgm2l1
gene id: 42514:pgm2l1
uniprot id: A0A3B4C0I5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

42514:hcrt
gene id: 42514:hcrt
uniprot id: A0A0F6NC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: Synapse
messages: Vesicle

42514:mlf1
gene id: 42514:mlf1
uniprot id: A0A3B4BVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

42514:LOC108412425
gene id: 42514:LOC108412425
uniprot id: A0A3B4C2N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

42514:LOC108412930
gene id: 42514:LOC108412930
uniprot id: A0A3B4DYR4
names: Similarity
messages: Belongs to the MHC class I family.

42514:LOC108415880
gene id: 42514:LOC108415880
uniprot id: A0A3B4D3G8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:topaz1
gene id: 42514:topaz1
uniprot id: A0A3B4C4A5
names: Function
messages: Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.

42514:aarsd1
gene id: 42514:aarsd1
uniprot id: A0A3B4BQL1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

42514:gabra6a
gene id: 42514:gabra6a
uniprot id: A0A3B4D0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:prickle2b
gene id: 42514:prickle2b
uniprot id: A0A3B4CC10
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

42514:kcnb1
gene id: 42514:kcnb1
uniprot id: A0A3B4DS48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: dendrite
messages: sarcolemma
messages: synaptosome

42514:si:zfos-323e3.4
gene id: 42514:si:zfos-323e3.4
uniprot id: A0A3B4DHR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

42514:mdga2a
gene id: 42514:mdga2a
uniprot id: A0A3B4C7V3
uniprot id: A0A3B4C7W9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:tmem87b
gene id: 42514:tmem87b
uniprot id: A0A3B4DME2
names: Subcellular Location Annotation
messages: Membrane

42514:ap5m1
gene id: 42514:ap5m1
uniprot id: A0A3B4E4I5
names: Subcellular Location Annotation
names: Subunit
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

42514:zic1
gene id: 42514:zic1
uniprot id: A0A3B4ERY5
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

42514:adgrd2
gene id: 42514:adgrd2
uniprot id: A0A3B4BKF9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:plcd1b
gene id: 42514:plcd1b
uniprot id: A0A3B4DDM8
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

42514:LOC108425036
gene id: 42514:LOC108425036
uniprot id: A0A3B4CNL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

42514:pex5la
gene id: 42514:pex5la
uniprot id: A0A3B4D602
uniprot id: A0A3B4D8F0
uniprot id: A0A3B4EL78
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

42514:LOC108437551
gene id: 42514:LOC108437551
uniprot id: A0A3B4DTY6
names: Similarity
messages: Belongs to the EVA1 family.

42514:ptpn20
gene id: 42514:ptpn20
uniprot id: A0A3B4DI77
uniprot id: A0A3B4DI87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

42514:LOC108424097
gene id: 42514:LOC108424097
uniprot id: A0A3B4BQ40
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:gad2
gene id: 42514:gad2
uniprot id: A0A3B4DG70
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

42514:nav1a
gene id: 42514:nav1a
uniprot id: A0A3B4EFD3
names: Similarity
messages: Belongs to the Nav/unc-53 family.

42514:kcmf1
gene id: 42514:kcmf1
uniprot id: A0A3B4BPX1
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

42514:sft2d2b
gene id: 42514:sft2d2b
uniprot id: A0A3B4CXM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

42514:LOC108436081
gene id: 42514:LOC108436081
uniprot id: A0A3B4CTY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

42514:si:dkey-21c19.3
gene id: 42514:si:dkey-21c19.3
uniprot id: A0A3B4E983
names: Similarity
messages: Belongs to the peptidase C48 family.

42514:xkr6b
gene id: 42514:xkr6b
uniprot id: A0A3B4D9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:naxe
gene id: 42514:naxe
uniprot id: A0A3B4BP77
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted

42514:got1l1
gene id: 42514:got1l1
uniprot id: A0A3B4CK82
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

42514:sema4d
gene id: 42514:sema4d
uniprot id: A0A3B4BUU1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:acer2
gene id: 42514:acer2
uniprot id: A0A3B4E6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

42514:zfyve16
gene id: 42514:zfyve16
uniprot id: A0A3B4DUJ4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

42514:gpr143
gene id: 42514:gpr143
uniprot id: A0A3B4BZ35
names: Subcellular Location Annotation
messages: Membrane

42514:naa40
gene id: 42514:naa40
uniprot id: A0A3B4CN96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

42514:hephl1a
gene id: 42514:hephl1a
uniprot id: A0A3B4E7S9
names: Similarity
messages: Belongs to the multicopper oxidase family.

42514:tnr
gene id: 42514:tnr
uniprot id: A0A3B4CDM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

42514:crybb3
gene id: 42514:crybb3
uniprot id: A0A3B4BPQ5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:LOC108414695
gene id: 42514:LOC108414695
uniprot id: A0A3B4CIP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

42514:trnau1apa
gene id: 42514:trnau1apa
uniprot id: A0A3B4EF10
names: Similarity
messages: Belongs to the RRM TRSPAP family.

42514:LOC108423976
gene id: 42514:LOC108423976
uniprot id: A0A3B4DS83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:b3galt6
gene id: 42514:b3galt6
uniprot id: A0A3B4C488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:adamts6
gene id: 42514:adamts6
uniprot id: A0A3B4DPY8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:dvl1a
gene id: 42514:dvl1a
uniprot id: A0A3B4CWG7
names: Similarity
messages: Belongs to the DSH family.

42514:aplp2
gene id: 42514:aplp2
uniprot id: A0A3B4C7D5
uniprot id: A0A3B4C9H8
uniprot id: A0A3B4C9K6
uniprot id: A0A3B4DWY5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:mustn1a
gene id: 42514:mustn1a
uniprot id: A0A3B4CIG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

42514:pds5a
gene id: 42514:pds5a
uniprot id: A0A3B4EL30
names: Subcellular Location Annotation
messages: Nucleus

42514:basp1
gene id: 42514:basp1
uniprot id: A0A3B4E7J0
names: Similarity
messages: Belongs to the BASP1 family.

42514:ergic2
gene id: 42514:ergic2
uniprot id: A0A3B4CQK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

42514:dgcr6
gene id: 42514:dgcr6
uniprot id: A0A3B4DEY4
names: Similarity
messages: Belongs to the gonadal family.

42514:ppfibp1a
gene id: 42514:ppfibp1a
uniprot id: A0A3B4BU68
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

42514:fscn2a
gene id: 42514:fscn2a
uniprot id: A0A3B4BT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

42514:fuca1.2
gene id: 42514:fuca1.2
uniprot id: A0A3B4BZZ4
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

42514:hmx4
gene id: 42514:hmx4
uniprot id: A0A3B4C9U1
names: Subcellular Location Annotation
messages: Nucleus

42514:gstt1a
gene id: 42514:gstt1a
uniprot id: A0A3B4C0H5
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

42514:med15
gene id: 42514:med15
uniprot id: A0A3B4BVX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:LOC108426312
gene id: 42514:LOC108426312
uniprot id: A0A3B4DRN1
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

42514:abcd4
gene id: 42514:abcd4
uniprot id: A0A3B4DT95
names: Subcellular Location Annotation
messages: Membrane

42514:trpv4
gene id: 42514:trpv4
uniprot id: A0A3B4BRR7
names: Subcellular Location Annotation
messages: Membrane

42514:fah
gene id: 42514:fah
uniprot id: A0A3B4DVY3
names: Similarity
messages: Belongs to the FAH family.

42514:LOC108413120
gene id: 42514:LOC108413120
uniprot id: A0A3B4BWG2
uniprot id: A0A3B4BZF2
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

42514:dip2bb
gene id: 42514:dip2bb
uniprot id: A0A3B4CD85
uniprot id: A0A3B4DY37
uniprot id: A0A3B4DY97
uniprot id: A0A3B4DZ95
names: Similarity
messages: Belongs to the DIP2 family.

42514:si:ch211-195b13.1
gene id: 42514:si:ch211-195b13.1
uniprot id: A0A3B4E0E4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

42514:gata5
gene id: 42514:gata5
uniprot id: A0A3B4DNR4
names: Subcellular Location Annotation
messages: Nucleus

42514:smarcad1a
gene id: 42514:smarcad1a
uniprot id: A0A3B4DNT6
names: Subcellular Location Annotation
messages: Chromosome

42514:anxa4
gene id: 42514:anxa4
uniprot id: A0A3B4E4P8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

42514:abcb4
gene id: 42514:abcb4
uniprot id: A0A3B4E1S3
names: Subcellular Location Annotation
messages: Membrane

42514:faah2a
gene id: 42514:faah2a
uniprot id: A0A3B4C9T2
names: Similarity
messages: Belongs to the amidase family.

42514:strn
gene id: 42514:strn
uniprot id: A0A3B4C8Q5
uniprot id: A0A3B4DWJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

42514:top2a
gene id: 42514:top2a
uniprot id: A0A3B4DIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

42514:pdia7
gene id: 42514:pdia7
uniprot id: A0A3B4DFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

42514:LOC108426655
gene id: 42514:LOC108426655
uniprot id: A0A3B4D7K9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

42514:tyms
gene id: 42514:tyms
uniprot id: A0A3B4BNQ6
names: Similarity
messages: Belongs to the thymidylate synthase family.

42514:tfeb
gene id: 42514:tfeb
uniprot id: A0A3B4DTJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

42514:tmem151bb
gene id: 42514:tmem151bb
uniprot id: A0A3B4DJN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

42514:kmt5aa
gene id: 42514:kmt5aa
uniprot id: A0A3B4E2S4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

42514:tmem132e
gene id: 42514:tmem132e
uniprot id: A0A3B4CFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

42514:LOC108439348
gene id: 42514:LOC108439348
uniprot id: A0A3B4D9H3
names: Similarity
messages: Belongs to the peptidase M14 family.

42514:opn7b
gene id: 42514:opn7b
uniprot id: A0A3B4EG34
names: Subcellular Location Annotation
messages: Membrane

42514:rnaseh2a
gene id: 42514:rnaseh2a
uniprot id: A0A3B4CUE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

42514:pias4a
gene id: 42514:pias4a
uniprot id: A0A3B4CIW3
names: Similarity
messages: Belongs to the PIAS family.

42514:coq6
gene id: 42514:coq6
uniprot id: A0A3B4E2Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

42514:b3galt2
gene id: 42514:b3galt2
uniprot id: A0A3B4DM44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:LOC108427450
gene id: 42514:LOC108427450
uniprot id: A0A3B4DXL5
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

42514:ubr3
gene id: 42514:ubr3
uniprot id: A0A3B4CR26
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

42514:eif3d
gene id: 42514:eif3d
uniprot id: A0A3B4DH79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

42514:slc9a8
gene id: 42514:slc9a8
uniprot id: A0A3B4D2L7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

42514:taf9
gene id: 42514:taf9
uniprot id: A0A3B4CG15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

42514:si:dkey-22n8.3
gene id: 42514:si:dkey-22n8.3
uniprot id: A0A3B4D428
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion

42514:LOC108442659
gene id: 42514:LOC108442659
uniprot id: A0A3B4BRD1
names: Similarity
messages: Belongs to the FAM83 family.

42514:efs
gene id: 42514:efs
uniprot id: A0A3B4CZQ1
names: Similarity
messages: Belongs to the CAS family.

42514:LOC108440017
gene id: 42514:LOC108440017
uniprot id: A0A3B4CX21
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:myo10
gene id: 42514:myo10
uniprot id: A0A3B4CVZ1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:mrps15
gene id: 42514:mrps15
uniprot id: A0A3B4E220
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

42514:nbn
gene id: 42514:nbn
uniprot id: A0A3B4D9X0
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

42514:fzd8a
gene id: 42514:fzd8a
uniprot id: A0A3B4EPW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

42514:tecra
gene id: 42514:tecra
uniprot id: A0A3B4CFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

42514:LOC108431411
gene id: 42514:LOC108431411
uniprot id: A0A3B4C3R1
names: Similarity
messages: Belongs to the RBR family.

42514:ptger1c
gene id: 42514:ptger1c
uniprot id: A0A3B4E214
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:foxf2a
gene id: 42514:foxf2a
uniprot id: A0A3B4DE54
names: Subcellular Location Annotation
messages: Nucleus

42514:trabd2b
gene id: 42514:trabd2b
uniprot id: A0A3B4CMV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

42514:hspa14
gene id: 42514:hspa14
uniprot id: A0A3B4DNV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: cytosol

42514:abch1
gene id: 42514:abch1
uniprot id: A0A3B4EH73
names: Subcellular Location Annotation
messages: Membrane

42514:prdm12b
gene id: 42514:prdm12b
uniprot id: A0A3B4D3N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

42514:LOC108429762
gene id: 42514:LOC108429762
uniprot id: A0A3B4C4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

42514:hddc2
gene id: 42514:hddc2
uniprot id: A0A3B4BYX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

42514:pelo
gene id: 42514:pelo
uniprot id: A0A3B4DVR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.
messages: Cytoplasm

42514:prkcq
gene id: 42514:prkcq
uniprot id: A0A3B4DGT9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

42514:snrpa
gene id: 42514:snrpa
uniprot id: A0A3B4DE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

42514:LOC108436367
gene id: 42514:LOC108436367
uniprot id: A0A3B4C3Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

42514:pkn3
gene id: 42514:pkn3
uniprot id: A0A3B4DUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

42514:grinaa
gene id: 42514:grinaa
uniprot id: A0A3B4D4I2
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108434905
gene id: 42514:LOC108434905
uniprot id: A0A3B4ERC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

42514:emc2
gene id: 42514:emc2
uniprot id: A0A3B4DR83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

42514:LOC108427579
gene id: 42514:LOC108427579
uniprot id: A0A3B4BW54
names: Subcellular Location Annotation
messages: Membrane

42514:trim35-13
gene id: 42514:trim35-13
uniprot id: A0A3B4CDH2
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108437283
gene id: 42514:LOC108437283
uniprot id: A0A3B4D0T9
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108430445
gene id: 42514:LOC108430445
uniprot id: A0A3B4DFX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

42514:olfm2a
gene id: 42514:olfm2a
uniprot id: A0A3B4CJS9
uniprot id: A0A3B4E4B7
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

42514:tgm5l
gene id: 42514:tgm5l
uniprot id: A0A3B4ERE7
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

42514:s1pr3a
gene id: 42514:s1pr3a
uniprot id: A0A3B4DPC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:nsg2
gene id: 42514:nsg2
uniprot id: A0A3B4DC01
names: Similarity
messages: Belongs to the NSG family.

42514:si:dkey-112m2.1
gene id: 42514:si:dkey-112m2.1
uniprot id: A0A3B4BS74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

42514:pabpc1b
gene id: 42514:pabpc1b
uniprot id: A0A3B4D580
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

42514:idh3g
gene id: 42514:idh3g
uniprot id: A0A3B4EB11
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

42514:atp2b2
gene id: 42514:atp2b2
uniprot id: A0A3B4BU02
uniprot id: A0A3B4DKK6
uniprot id: A0A3B4DKL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:dlx3b
gene id: 42514:dlx3b
uniprot id: A0A3B4C6A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

42514:LOC108428262
gene id: 42514:LOC108428262
uniprot id: A0A3B4CYJ6
names: Similarity
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.

42514:pknox1.1
gene id: 42514:pknox1.1
uniprot id: A0A3B4CHJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

42514:rpl31
gene id: 42514:rpl31
uniprot id: A0A3B4E7Z7
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

42514:cpa6
gene id: 42514:cpa6
uniprot id: A0A3B4CPC6
names: Similarity
messages: Belongs to the peptidase M14 family.

42514:prdm6
gene id: 42514:prdm6
uniprot id: A0A3B4DNH2
names: Subcellular Location Annotation
messages: Nucleus

42514:syngr3a
gene id: 42514:syngr3a
uniprot id: A0A3B4D070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

42514:mtm1
gene id: 42514:mtm1
uniprot id: A0A3B4CR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

42514:popdc3
gene id: 42514:popdc3
uniprot id: A0A3B4E3F0
names: Similarity
messages: Belongs to the popeye family.

42514:zgc:136971
gene id: 42514:zgc:136971
uniprot id: A0A3B4E4K1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.

42514:gpr180
gene id: 42514:gpr180
uniprot id: A0A3B4BXK7
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108430712
gene id: 42514:LOC108430712
uniprot id: A0A3B4DYX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:hars
gene id: 42514:hars
uniprot id: A0A3B4CAQ9
uniprot id: A0A3B4DWF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

42514:tgfb2
gene id: 42514:tgfb2
uniprot id: A0A3B4C1I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

42514:ero1b
gene id: 42514:ero1b
uniprot id: A0A3B4C8L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

42514:LOC108411190
gene id: 42514:LOC108411190
uniprot id: A0A3B4DY22
names: Similarity
messages: Belongs to the NLRP family.

42514:LOC108432484
gene id: 42514:LOC108432484
uniprot id: A0A3B4C1S7
uniprot id: A0A3B4C2X0
names: Subcellular Location Annotation
messages: Membrane

42514:slc6a3
gene id: 42514:slc6a3
uniprot id: A0A3B4C769
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

42514:slc17a6a
gene id: 42514:slc17a6a
uniprot id: A0A3B4BMJ3
names: Subcellular Location Annotation
messages: Membrane

42514:si:ch211-71n6.4
gene id: 42514:si:ch211-71n6.4
uniprot id: A0A3B4CT84
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

42514:clec14a
gene id: 42514:clec14a
uniprot id: A0A3B4DK91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:creg1
gene id: 42514:creg1
uniprot id: A0A3B4DSW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

42514:diras1b
gene id: 42514:diras1b
uniprot id: A0A3B4DZE1
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:id2a
gene id: 42514:id2a
uniprot id: A0A3B4CJJ7
names: Subcellular Location Annotation
messages: Nucleus

42514:htr5ab
gene id: 42514:htr5ab
uniprot id: A0A3B4CRR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:cln8
gene id: 42514:cln8
uniprot id: A0A3B4D2D4
names: Subcellular Location Annotation
messages: Membrane

42514:atp2a3
gene id: 42514:atp2a3
uniprot id: A0A3B4C9A5
uniprot id: A0A3B4C9B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

42514:zgc:92591
gene id: 42514:zgc:92591
uniprot id: A0A3B4CDF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:wu:fb13g09
gene id: 42514:wu:fb13g09
uniprot id: A0A3B4CJS8
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108439868
gene id: 42514:LOC108439868
uniprot id: A0A3B4D937
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

42514:LOC108441812
gene id: 42514:LOC108441812
uniprot id: A0A3B4CI06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:ddb2
gene id: 42514:ddb2
uniprot id: A0A3B4CAT8
uniprot id: A0A3B4CAU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

42514:pvalb1
gene id: 42514:pvalb1
uniprot id: A0A3B4E4R8
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

42514:fam163a
gene id: 42514:fam163a
uniprot id: A0A3B4CUE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

42514:kcnj10a
gene id: 42514:kcnj10a
uniprot id: A0A3B4C2Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:zgc:171971
gene id: 42514:zgc:171971
uniprot id: A0A3B4E4I3
names: Subcellular Location Annotation
messages: Nucleus

42514:hint2
gene id: 42514:hint2
uniprot id: A0A3B4EPE9
names: Similarity
messages: Belongs to the HINT family.

42514:nutf2l
gene id: 42514:nutf2l
uniprot id: A0A3B4EDR0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

42514:henmt1
gene id: 42514:henmt1
uniprot id: A0A3B4DKY4
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

42514:snrpd1
gene id: 42514:snrpd1
uniprot id: A0A3B4CL64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

42514:yes1
gene id: 42514:yes1
uniprot id: A0A3B4DA81
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:neil3
gene id: 42514:neil3
uniprot id: A0A3B4EA79
names: Similarity
messages: Belongs to the FPG family.

42514:zic6
gene id: 42514:zic6
uniprot id: A0A3B4CS83
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

42514:rtn4a
gene id: 42514:rtn4a
uniprot id: A0A3B4BSX0
uniprot id: A0A3B4DJR6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108427062
gene id: 42514:LOC108427062
uniprot id: A0A3B4DHQ0
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:zmp:0000000711
gene id: 42514:zmp:0000000711
uniprot id: A0A3B4D7E2
uniprot id: A0A3B4EGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

42514:tmem175
gene id: 42514:tmem175
uniprot id: A0A3B4CNY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

42514:LOC108441069
gene id: 42514:LOC108441069
uniprot id: A0A3B4EIQ3
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

42514:leap2
gene id: 42514:leap2
uniprot id: A0A3B4E605
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

42514:ppp3ccb
gene id: 42514:ppp3ccb
uniprot id: A0A3B4EF52
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

42514:LOC108431838
gene id: 42514:LOC108431838
uniprot id: A0A3B4CG99
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

42514:tlcd3a
gene id: 42514:tlcd3a
uniprot id: A0A3B4EQY4
names: Subcellular Location Annotation
messages: Membrane

42514:nfascb
gene id: 42514:nfascb
uniprot id: A0A3B4CE26
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

42514:rps28
gene id: 42514:rps28
uniprot id: A0A3B4EGG4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

42514:prc1b
gene id: 42514:prc1b
uniprot id: A0A3B4CW10
names: Similarity
messages: Belongs to the MAP65/ASE1 family.

42514:ccdc47
gene id: 42514:ccdc47
uniprot id: A0A3B4CIG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC47 family.
messages: Rough endoplasmic reticulum membrane

42514:jmy
gene id: 42514:jmy
uniprot id: A0A3B4BQV7
names: Subcellular Location Annotation
messages: Membrane

42514:naa25
gene id: 42514:naa25
uniprot id: A0A3B4C6H8
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

42514:LOC108441395
gene id: 42514:LOC108441395
uniprot id: A0A3B4DXZ2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:LOC108439508
gene id: 42514:LOC108439508
uniprot id: A0A3B4CNT6
names: Similarity
messages: Belongs to the SH3RF family.

42514:tacr3l
gene id: 42514:tacr3l
uniprot id: A0A3B4DS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:hrh2b
gene id: 42514:hrh2b
uniprot id: A0A3B4D8S9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:polr2l
gene id: 42514:polr2l
uniprot id: A0A3B4CDI4
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

42514:hoxc6b
gene id: 42514:hoxc6b
uniprot id: A0A3B4BLW1
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108425703
gene id: 42514:LOC108425703
uniprot id: A0A3B4DZK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

42514:LOC108438444
gene id: 42514:LOC108438444
uniprot id: A0A3B4ECF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:irf3
gene id: 42514:irf3
uniprot id: A0A3B4CXD9
names: Subcellular Location Annotation
messages: Nucleus

42514:tmem183a
gene id: 42514:tmem183a
uniprot id: A0A3B4C0X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

42514:sdha
gene id: 42514:sdha
uniprot id: A0A3B4C002
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

42514:dna2
gene id: 42514:dna2
uniprot id: A0A3B4BP31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

42514:tmem135
gene id: 42514:tmem135
uniprot id: A0A3B4CMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane

42514:papss2b
gene id: 42514:papss2b
uniprot id: A0A3B4BT60
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

42514:twf2b
gene id: 42514:twf2b
uniprot id: A0A3B4C599
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

42514:lpar6b
gene id: 42514:lpar6b
uniprot id: A0A3B4CEL8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:gatc
gene id: 42514:gatc
uniprot id: A0A3B4DLP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

42514:uxs1
gene id: 42514:uxs1
uniprot id: A0A3B4DML1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

42514:gdnfa
gene id: 42514:gdnfa
uniprot id: A0A3B4EB85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Homodimer; disulfide-linked.
messages: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
messages: Secreted

42514:LOC108444047
gene id: 42514:LOC108444047
uniprot id: A0A3B4D121
names: Similarity
messages: Belongs to the peptidase S14 family.

42514:dlx2a
gene id: 42514:dlx2a
uniprot id: A0A3B4CQ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

42514:LOC108444564
gene id: 42514:LOC108444564
uniprot id: A0A3B4EIF2
names: Similarity
messages: Belongs to the cornifelin family.

42514:cnn1a
gene id: 42514:cnn1a
uniprot id: A0A3B4C0E1
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

42514:cd82a
gene id: 42514:cd82a
uniprot id: A0A3B4CEN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:acaa2
gene id: 42514:acaa2
uniprot id: A0A3B4BPW8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

42514:camk2b1
gene id: 42514:camk2b1
uniprot id: A0A3B4BYU0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

42514:mrpl27
gene id: 42514:mrpl27
uniprot id: A0A3B4C066
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

42514:smad6a
gene id: 42514:smad6a
uniprot id: A0A3B4CEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:dusp4
gene id: 42514:dusp4
uniprot id: A0A3B4BVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

42514:prkcda
gene id: 42514:prkcda
uniprot id: A0A3B4CHJ9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

42514:ndufs5
gene id: 42514:ndufs5
uniprot id: A0A3B4BSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

42514:ube2g2
gene id: 42514:ube2g2
uniprot id: A0A3B4DMI2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:slc2a11l
gene id: 42514:slc2a11l
uniprot id: A0A3B4BZ19
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:mphosph10
gene id: 42514:mphosph10
uniprot id: A0A3B4CUM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

42514:aldh5a1
gene id: 42514:aldh5a1
uniprot id: A0A3B4CZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

42514:mgrn1a
gene id: 42514:mgrn1a
uniprot id: A0A3B4C3A4
uniprot id: A0A3B4DRP6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

42514:s1pr1
gene id: 42514:s1pr1
uniprot id: A0A3B4EEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:tlr21
gene id: 42514:tlr21
uniprot id: A0A3B4E727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

42514:notum1a
gene id: 42514:notum1a
uniprot id: A0A3B4D0P4
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

42514:anapc13
gene id: 42514:anapc13
uniprot id: A0A3B4CJ01
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

42514:gmppab
gene id: 42514:gmppab
uniprot id: A0A3B4CVV4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

42514:LOC108410647
gene id: 42514:LOC108410647
uniprot id: A0A3B4E655
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:arcn1b
gene id: 42514:arcn1b
uniprot id: A0A3B4BUW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

42514:rspo2
gene id: 42514:rspo2
uniprot id: A0A3B4C1Z7
names: Similarity
messages: Belongs to the R-spondin family.

42514:sema4ba
gene id: 42514:sema4ba
uniprot id: A0A3B4DU63
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:brinp2
gene id: 42514:brinp2
uniprot id: A0A3B4BVN5
names: Similarity
messages: Belongs to the BRINP family.

42514:scarb2a
gene id: 42514:scarb2a
uniprot id: A0A3B4EQW6
names: Similarity
messages: Belongs to the CD36 family.

42514:LOC108423632
gene id: 42514:LOC108423632
uniprot id: A0A3B4EP44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid ceramidase family.
messages: Lysosome

42514:tom1
gene id: 42514:tom1
uniprot id: A0A3B4BRM9
uniprot id: A0A3B4DK78
names: Similarity
messages: Belongs to the TOM1 family.

42514:tbx16
gene id: 42514:tbx16
uniprot id: A0A3B4EA06
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:lactb2
gene id: 42514:lactb2
uniprot id: A0A3B4EAD8
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

42514:rgmb
gene id: 42514:rgmb
uniprot id: A0A3B4EQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

42514:utp15
gene id: 42514:utp15
uniprot id: A0A3B4D832
names: Subcellular Location Annotation
messages: nucleolus

42514:ube2ia
gene id: 42514:ube2ia
uniprot id: A0A3B4DM14
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:hoxb6b
gene id: 42514:hoxb6b
uniprot id: A0A3B4CY00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:nox1
gene id: 42514:nox1
uniprot id: A0A3B4E4D8
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108438035
gene id: 42514:LOC108438035
uniprot id: A0A3B4C5D3
names: Similarity
messages: Belongs to the amidase family.

42514:mal2
gene id: 42514:mal2
uniprot id: A0A3B4DP73
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108434747
gene id: 42514:LOC108434747
uniprot id: A0A3B4DZ29
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

42514:dynlt5
gene id: 42514:dynlt5
uniprot id: A0A3B4CI38
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

42514:mtmr6
gene id: 42514:mtmr6
uniprot id: A0A3B4D1Q6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

42514:crppa
gene id: 42514:crppa
uniprot id: A0A3B4BVA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

42514:LOC108414284
gene id: 42514:LOC108414284
uniprot id: A0A3B4BJT7
uniprot id: A0A3B4DH14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

42514:gna13a
gene id: 42514:gna13a
uniprot id: A0A3B4CAD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

42514:bace1
gene id: 42514:bace1
uniprot id: A0A3B4BPE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

42514:epdr1
gene id: 42514:epdr1
uniprot id: A0A3B4D7C5
names: Similarity
messages: Belongs to the ependymin family.

42514:ccng1
gene id: 42514:ccng1
uniprot id: A0A3B4D0D9
names: Similarity
messages: Belongs to the cyclin family.

42514:LOC108435868
gene id: 42514:LOC108435868
uniprot id: A0A3B4C729
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

42514:bace2
gene id: 42514:bace2
uniprot id: A0A3B4DVD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

42514:spon2a
gene id: 42514:spon2a
uniprot id: A0A3B4D475
names: Subcellular Location Annotation
messages: extracellular matrix

42514:ntrk3a
gene id: 42514:ntrk3a
uniprot id: A0A3B4CJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:nup58
gene id: 42514:nup58
uniprot id: A0A3B4CZH1
uniprot id: A0A3B4EBM6
names: Subcellular Location Annotation
messages: nuclear pore complex

42514:hibadhb
gene id: 42514:hibadhb
uniprot id: A0A3B4BW05
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

42514:cry3a
gene id: 42514:cry3a
uniprot id: A0A3B4EEE4
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

42514:cenpk
gene id: 42514:cenpk
uniprot id: A0A3B4DPF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

42514:mb21d2
gene id: 42514:mb21d2
uniprot id: A0A3B4DDV3
names: Similarity
messages: Belongs to the mab-21 family.

42514:adcy3a
gene id: 42514:adcy3a
uniprot id: A0A3B4DPT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

42514:LOC108439614
gene id: 42514:LOC108439614
uniprot id: A0A3B4E2G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

42514:ppp2r5ca
gene id: 42514:ppp2r5ca
uniprot id: A0A3B4C5G9
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

42514:rab14l
gene id: 42514:rab14l
uniprot id: A0A3B4CBT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

42514:epha2a
gene id: 42514:epha2a
uniprot id: A0A3B4C4L6
names: Subcellular Location Annotation
messages: Membrane

42514:ythdf2
gene id: 42514:ythdf2
uniprot id: A0A3B4BU58
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

42514:cftr
gene id: 42514:cftr
uniprot id: A0A3B4C502
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Recycling endosome membrane

42514:tubb1
gene id: 42514:tubb1
uniprot id: A0A3B4DT16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:tmtops2a
gene id: 42514:tmtops2a
uniprot id: A0A3B4BWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

42514:dok6
gene id: 42514:dok6
uniprot id: A0A3B4EET3
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

42514:zgc:136908
gene id: 42514:zgc:136908
uniprot id: A0A3B4D5A1
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:gjc2
gene id: 42514:gjc2
uniprot id: A0A3B4DH05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:nol11
gene id: 42514:nol11
uniprot id: A0A3B4DCX9
names: Subcellular Location Annotation
messages: nucleolus

42514:prickle1a
gene id: 42514:prickle1a
uniprot id: A0A3B4CNI1
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

42514:dyrk4
gene id: 42514:dyrk4
uniprot id: A0A3B4BX37
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

42514:gucy2f
gene id: 42514:gucy2f
uniprot id: A0A3B4DYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

42514:rxraa
gene id: 42514:rxraa
uniprot id: A0A3B4D2I9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

42514:ube2na
gene id: 42514:ube2na
uniprot id: A0A3B4E3V0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:LOC108429347
gene id: 42514:LOC108429347
uniprot id: A0A3B4DGU4
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

42514:stxbp5a
gene id: 42514:stxbp5a
uniprot id: A0A3B4BSS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

42514:LOC108439566
gene id: 42514:LOC108439566
uniprot id: A0A3B4E8U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

42514:LOC108436869
gene id: 42514:LOC108436869
uniprot id: A0A3B4D5B1
names: Subcellular Location Annotation
messages: Membrane

42514:pgap3
gene id: 42514:pgap3
uniprot id: A0A3B4BWI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:eomesb
gene id: 42514:eomesb
uniprot id: A0A3B4DDJ1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:glrba
gene id: 42514:glrba
uniprot id: A0A3B4EL48
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:spon1b
gene id: 42514:spon1b
uniprot id: A0A3B4BUZ4
names: Subcellular Location Annotation
messages: extracellular matrix

42514:mrpl47
gene id: 42514:mrpl47
uniprot id: A0A3B4D902
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

42514:LOC108422651
gene id: 42514:LOC108422651
uniprot id: A0A3B4CA71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

42514:pkp1b
gene id: 42514:pkp1b
uniprot id: A0A3B4BRT3
names: Similarity
messages: Belongs to the beta-catenin family.

42514:si:dkey-172j4.3
gene id: 42514:si:dkey-172j4.3
uniprot id: A0A3B4C6V4
uniprot id: A0A3B4DXF8
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

42514:LOC108414371
gene id: 42514:LOC108414371
uniprot id: A0A3B4DS07
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

42514:LOC108437369
gene id: 42514:LOC108437369
uniprot id: A0A3B4EBF3
names: Similarity
messages: Belongs to the asteroid family.

42514:optn
gene id: 42514:optn
uniprot id: A0A3B4DQV4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

42514:eva1ba
gene id: 42514:eva1ba
uniprot id: A0A3B4E1S9
names: Similarity
messages: Belongs to the EVA1 family.

42514:zgc:152891
gene id: 42514:zgc:152891
uniprot id: A0A3B4CCI5
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:gnb4a
gene id: 42514:gnb4a
uniprot id: A0A3B4C0I2
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

42514:stx6
gene id: 42514:stx6
uniprot id: A0A3B4CY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

42514:LOC108440715
gene id: 42514:LOC108440715
uniprot id: A0A3B4CIE6
names: Similarity
messages: Belongs to the MHC class I family.

42514:stn1
gene id: 42514:stn1
uniprot id: A0A3B4BTF1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

42514:hlcs
gene id: 42514:hlcs
uniprot id: A0A3B4CMD3
names: Similarity
messages: Belongs to the biotin--protein ligase family.

42514:gna13b
gene id: 42514:gna13b
uniprot id: A0A3B4C8K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

42514:ighmbp2
gene id: 42514:ighmbp2
uniprot id: A0A3B4C932
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

42514:LOC108436128
gene id: 42514:LOC108436128
uniprot id: A0A3B4CXY6
names: Similarity
messages: Belongs to the lipin family.

42514:vars2
gene id: 42514:vars2
uniprot id: A0A3B4EJX3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

42514:asrgl1
gene id: 42514:asrgl1
uniprot id: A0A3B4BUH2
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

42514:gga3b
gene id: 42514:gga3b
uniprot id: A0A3B4CJB9
uniprot id: A0A3B4DZK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

42514:sppl3
gene id: 42514:sppl3
uniprot id: A0A3B4EC13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

42514:brpf1
gene id: 42514:brpf1
uniprot id: A0A3B4DIS4
names: Subcellular Location Annotation
messages: Nucleus

42514:rrp15
gene id: 42514:rrp15
uniprot id: A0A3B4C4Z5
names: Similarity
messages: Belongs to the RRP15 family.

42514:baz1b
gene id: 42514:baz1b
uniprot id: A0A3B4EMN6
names: Subcellular Location Annotation
messages: Nucleus

42514:slc2a15a
gene id: 42514:slc2a15a
uniprot id: A0A3B4DI56
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:efnb3b
gene id: 42514:efnb3b
uniprot id: A0A3B4DUQ1
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:nuf2
gene id: 42514:nuf2
uniprot id: A0A3B4DJC2
names: Similarity
messages: Belongs to the NUF2 family.

42514:washc3
gene id: 42514:washc3
uniprot id: A0A3B4CLI4
names: Similarity
messages: Belongs to the CCDC53 family.

42514:irak1bp1
gene id: 42514:irak1bp1
uniprot id: A0A3B4D8M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

42514:esco2
gene id: 42514:esco2
uniprot id: A0A3B4DQK8
names: Subcellular Location Annotation
messages: Nucleus

42514:tasorb
gene id: 42514:tasorb
uniprot id: A0A3B4DYK8
names: Similarity
messages: Belongs to the TASOR family.

42514:sec23a
gene id: 42514:sec23a
uniprot id: A0A3B4BTW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

42514:gadd45ab
gene id: 42514:gadd45ab
uniprot id: A0A3B4BUD6
names: Similarity
messages: Belongs to the GADD45 family.

42514:ndr2
gene id: 42514:ndr2
uniprot id: A0A3B4BNZ8
names: Similarity
messages: Belongs to the TGF-beta family.

42514:gdf9
gene id: 42514:gdf9
uniprot id: A0A3B4D3F8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

42514:hspb2
gene id: 42514:hspb2
uniprot id: A0A3B4CE68
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

42514:LOC108411208
gene id: 42514:LOC108411208
uniprot id: A0A3B4C7I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

42514:fam151b
gene id: 42514:fam151b
uniprot id: A0A3B4D232
names: Similarity
messages: Belongs to the FAM151 family.

42514:amigo3
gene id: 42514:amigo3
uniprot id: A0A3B4ER15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

42514:cant1a
gene id: 42514:cant1a
uniprot id: A0A3B4D0N8
names: Similarity
messages: Belongs to the apyrase family.

42514:gtf2a1l
gene id: 42514:gtf2a1l
uniprot id: A0A3B4CC77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

42514:agbl2
gene id: 42514:agbl2
uniprot id: A0A3B4CG48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

42514:chrm4a
gene id: 42514:chrm4a
uniprot id: A0A3B4D835
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

42514:LOC108431599
gene id: 42514:LOC108431599
uniprot id: A0A3B4DHH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

42514:gtpbp8
gene id: 42514:gtpbp8
uniprot id: A0A3B4D4T3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

42514:si:ch211-276f18.2
gene id: 42514:si:ch211-276f18.2
uniprot id: A0A3B4CVI7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

42514:pld1a
gene id: 42514:pld1a
uniprot id: A0A3B4CQ92
names: Similarity
messages: Belongs to the phospholipase D family.

42514:wars1
gene id: 42514:wars1
uniprot id: A0A3B4DVE6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

42514:rfx1a
gene id: 42514:rfx1a
uniprot id: A0A3B4EHQ9
names: Subcellular Location Annotation
messages: Nucleus

42514:nucb1
gene id: 42514:nucb1
uniprot id: A0A3B4EPG7
names: Similarity
messages: Belongs to the nucleobindin family.

42514:zgc:172145
gene id: 42514:zgc:172145
uniprot id: A0A3B4DDM3
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

42514:acss2
gene id: 42514:acss2
uniprot id: A0A3B4BXZ1
uniprot id: A0A3B4DN71
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:cd164l2
gene id: 42514:cd164l2
uniprot id: A0A3B4D813
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

42514:c16h5orf24
gene id: 42514:c16h5orf24
uniprot id: A0A3B4D7Y6
names: Similarity
messages: Belongs to the UPF0461 family.

42514:irf2bp2a
gene id: 42514:irf2bp2a
uniprot id: A0A3B4BR05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

42514:LOC108430443
gene id: 42514:LOC108430443
uniprot id: A0A3B4EMZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

42514:mrs2
gene id: 42514:mrs2
uniprot id: A0A3B4CWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

42514:jpt1a
gene id: 42514:jpt1a
uniprot id: A0A3B4C9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

42514:si:ch211-22d5.2
gene id: 42514:si:ch211-22d5.2
uniprot id: A0A3B4CEM0
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:slc37a4b
gene id: 42514:slc37a4b
uniprot id: A0A3B4DCK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

42514:ddx27
gene id: 42514:ddx27
uniprot id: A0A3B4E309
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:LOC108420818
gene id: 42514:LOC108420818
uniprot id: A0A3B4C6G8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:slc29a1a
gene id: 42514:slc29a1a
uniprot id: A0A3B4DLK9
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

42514:psme4a
gene id: 42514:psme4a
uniprot id: A0A3B4DD13
uniprot id: A0A3B4DDF1
names: Similarity
messages: Belongs to the BLM10 family.

42514:pmelb
gene id: 42514:pmelb
uniprot id: A0A3B4CW85
names: Similarity
messages: Belongs to the PMEL/NMB family.

42514:xpr1b
gene id: 42514:xpr1b
uniprot id: A0A3B4D5R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

42514:LOC108412792
gene id: 42514:LOC108412792
uniprot id: A0A3B4CVX2
names: Similarity
messages: Belongs to the MHC class I family.

42514:clstn2
gene id: 42514:clstn2
uniprot id: A0A3B4D2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

42514:itm2ba
gene id: 42514:itm2ba
uniprot id: A0A3B4E758
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

42514:eloal
gene id: 42514:eloal
uniprot id: A0A3B4D3H3
names: Subcellular Location Annotation
messages: Nucleus

42514:pparg
gene id: 42514:pparg
uniprot id: A0A3B4DJN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:galnt18b
gene id: 42514:galnt18b
uniprot id: A0A3B4CDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:nop56
gene id: 42514:nop56
uniprot id: A0A3B4EFX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

42514:mffa
gene id: 42514:mffa
uniprot id: A0A3B4CPE2
uniprot id: A0A3B4E4T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

42514:mmp23ba
gene id: 42514:mmp23ba
uniprot id: A0A3B4CMD7
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:adnp2a
gene id: 42514:adnp2a
uniprot id: A0A3B4D9T3
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108412826
gene id: 42514:LOC108412826
uniprot id: A0A3B4CL74
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

42514:zdhhc17
gene id: 42514:zdhhc17
uniprot id: A0A3B4BWK5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:slc6a4b
gene id: 42514:slc6a4b
uniprot id: A0A3B4DMH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:uba3
gene id: 42514:uba3
uniprot id: A0A3B4CGH6
uniprot id: A0A3B4E1K8
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.

42514:si:dkey-23f9.4
gene id: 42514:si:dkey-23f9.4
uniprot id: A0A3B4DTS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

42514:id3
gene id: 42514:id3
uniprot id: A0A3B4BR25
names: Subcellular Location Annotation
messages: Nucleus

42514:nup35
gene id: 42514:nup35
uniprot id: A0A3B4CBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

42514:cisd2
gene id: 42514:cisd2
uniprot id: A0A3B4DEB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

42514:LOC108411836
gene id: 42514:LOC108411836
uniprot id: A0A3B4CCQ2
names: Subcellular Location Annotation
messages: Membrane

42514:yy1b
gene id: 42514:yy1b
uniprot id: A0A3B4CU27
names: Similarity
messages: Belongs to the YY transcription factor family.

42514:sema4gb
gene id: 42514:sema4gb
uniprot id: A0A3B4EKR4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:mboat2b
gene id: 42514:mboat2b
uniprot id: A0A3B4EBG8
names: Subcellular Location Annotation
messages: Membrane

42514:lmnb1
gene id: 42514:lmnb1
uniprot id: A0A3B4BP03
names: Similarity
messages: Belongs to the intermediate filament family.

42514:clta
gene id: 42514:clta
uniprot id: A0A3B4CVN8
uniprot id: A0A3B4CXB4
uniprot id: A0A3B4CY07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

42514:id1
gene id: 42514:id1
uniprot id: A0A3B4DRP9
names: Subcellular Location Annotation
messages: Nucleus

42514:itpka
gene id: 42514:itpka
uniprot id: A0A3B4EBA2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

42514:smx5
gene id: 42514:smx5
uniprot id: A0A3B4DCP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

42514:paqr9
gene id: 42514:paqr9
uniprot id: A0A3B4DST9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:LOC108415799
gene id: 42514:LOC108415799
uniprot id: A0A3B4EEP5
names: Similarity
messages: Belongs to the asteroid family.

42514:eno1a
gene id: 42514:eno1a
uniprot id: A0A3B4CR57
names: Similarity
messages: Belongs to the enolase family.

42514:cdk19
gene id: 42514:cdk19
uniprot id: A0A3B4C535
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:ehd2a
gene id: 42514:ehd2a
uniprot id: A0A3B4E4Z8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

42514:bicc1b
gene id: 42514:bicc1b
uniprot id: A0A3B4CRE6
names: Similarity
messages: Belongs to the BicC family.

42514:nudt4b
gene id: 42514:nudt4b
uniprot id: A0A3B4CJV5
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

42514:LOC108440004
gene id: 42514:LOC108440004
uniprot id: A0A3B4D281
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:LOC108412762
gene id: 42514:LOC108412762
uniprot id: A0A3B4EDF8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

42514:rc3h2
gene id: 42514:rc3h2
uniprot id: A0A3B4CII4
names: Subcellular Location Annotation
messages: P-body

42514:wnk4a
gene id: 42514:wnk4a
uniprot id: A0A3B4D9L1
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

42514:LOC108429918
gene id: 42514:LOC108429918
uniprot id: A0A3B4EH91
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

42514:gnsb
gene id: 42514:gnsb
uniprot id: A0A3B4EJ93
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

42514:LOC108436565
gene id: 42514:LOC108436565
uniprot id: A0A3B4BS05
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:cldn5a
gene id: 42514:cldn5a
uniprot id: A0A3B4BMT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:mrpl9
gene id: 42514:mrpl9
uniprot id: A0A3B4EHJ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

42514:LOC108441318
gene id: 42514:LOC108441318
uniprot id: A0A3B4E2J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

42514:gfm1
gene id: 42514:gfm1
uniprot id: A0A3B4BVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

42514:rexo4
gene id: 42514:rexo4
uniprot id: A0A3B4CRK9
names: Similarity
messages: Belongs to the REXO4 family.

42514:pou2f1b
gene id: 42514:pou2f1b
uniprot id: A0A3B4D2K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

42514:gab1
gene id: 42514:gab1
uniprot id: A0A3B4D898
names: Similarity
messages: Belongs to the GAB family.

42514:ppp1r15b
gene id: 42514:ppp1r15b
uniprot id: A0A3B4DNC8
names: Similarity
messages: Belongs to the PPP1R15 family.

42514:pdgfrl
gene id: 42514:pdgfrl
uniprot id: A0A3B4E807
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.

42514:penka
gene id: 42514:penka
uniprot id: A0A3B4DEX9
names: Similarity
messages: Belongs to the opioid neuropeptide precursor family.

42514:slc30a1a
gene id: 42514:slc30a1a
uniprot id: A0A3B4DU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

42514:LOC108428227
gene id: 42514:LOC108428227
uniprot id: A0A3B4D1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

42514:aar2
gene id: 42514:aar2
uniprot id: A0A3B4CYA2
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

42514:brpf3b
gene id: 42514:brpf3b
uniprot id: A0A3B4CG74
names: Subcellular Location Annotation
messages: Nucleus

42514:si:dkey-42i9.4
gene id: 42514:si:dkey-42i9.4
uniprot id: A0A3B4BRU1
names: Similarity
messages: Belongs to the BTG family.

42514:c3h1orf43
gene id: 42514:c3h1orf43
uniprot id: A0A3B4EGB3
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

42514:ubac2
gene id: 42514:ubac2
uniprot id: A0A3B4DSP9
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108425188
gene id: 42514:LOC108425188
uniprot id: A0A3B4CE86
uniprot id: A0A3B4E1R2
uniprot id: A0A3B4E1S2
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

42514:LOC108433495
gene id: 42514:LOC108433495
uniprot id: A0A3B4E3K5
names: Subcellular Location Annotation
messages: Nucleus

42514:skor2
gene id: 42514:skor2
uniprot id: A0A3B4DA26
names: Similarity
messages: Belongs to the SKI family.

42514:fitm1l
gene id: 42514:fitm1l
uniprot id: A0A3B4E4X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol.
messages: Membrane

42514:echdc1
gene id: 42514:echdc1
uniprot id: A0A3B4C2L9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

42514:gria1b
gene id: 42514:gria1b
uniprot id: A0A3B4C095
uniprot id: A0A3B4DT01
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:chek1
gene id: 42514:chek1
uniprot id: A0A3B4CGR7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

42514:impg2b
gene id: 42514:impg2b
uniprot id: A0A3B4D775
uniprot id: A0A3B4DB86
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: interphotoreceptor matrix

42514:si:ch211-247n2.1
gene id: 42514:si:ch211-247n2.1
uniprot id: A0A3B4CFT9
uniprot id: A0A3B4CFU4
uniprot id: A0A3B4CH80
uniprot id: A0A3B4E2U0
names: Subcellular Location Annotation
messages: Membrane

42514:camkk1b
gene id: 42514:camkk1b
uniprot id: A0A3B4BVR3
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:eloca
gene id: 42514:eloca
uniprot id: A0A3B4D142
names: Similarity
messages: Belongs to the SKP1 family.

42514:LOC108424723
gene id: 42514:LOC108424723
uniprot id: A0A3B4DH85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

42514:map1lc3c
gene id: 42514:map1lc3c
uniprot id: A0A3B4CAR8
names: Similarity
messages: Belongs to the ATG8 family.

42514:parp10
gene id: 42514:parp10
uniprot id: A0A3B4D187
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:tcirg1a
gene id: 42514:tcirg1a
uniprot id: A0A3B4CEB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

42514:ap3m1
gene id: 42514:ap3m1
uniprot id: A0A3B4CC58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.

42514:cript
gene id: 42514:cript
uniprot id: A0A3B4BX66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

42514:mapk3
gene id: 42514:mapk3
uniprot id: A0A3B4EA36
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

42514:slc13a3
gene id: 42514:slc13a3
uniprot id: A0A3B4CLK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

42514:myoz1a
gene id: 42514:myoz1a
uniprot id: A0A3B4DIW7
names: Similarity
messages: Belongs to the myozenin family.

42514:abcb11b
gene id: 42514:abcb11b
uniprot id: A0A3B4DWT9
names: Subcellular Location Annotation
messages: Membrane

42514:ankhb
gene id: 42514:ankhb
uniprot id: A0A3B4EFQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

42514:zgc:113333
gene id: 42514:zgc:113333
uniprot id: A0A3B4D828
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

42514:chmp4c
gene id: 42514:chmp4c
uniprot id: A0A3B4DLE8
names: Similarity
messages: Belongs to the SNF7 family.

42514:mb
gene id: 42514:mb
uniprot id: A0A3B4DVU6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

42514:slc35d2
gene id: 42514:slc35d2
uniprot id: A0A3B4DGJ3
names: Subcellular Location Annotation
messages: Membrane

42514:hsp90aa1.2
gene id: 42514:hsp90aa1.2
uniprot id: A0A3B4EA59
names: Similarity
messages: Belongs to the heat shock protein 90 family.

42514:trappc6b
gene id: 42514:trappc6b
uniprot id: A0A3B4DA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

42514:chmp1b
gene id: 42514:chmp1b
uniprot id: A0A3B4DJ59
names: Similarity
messages: Belongs to the SNF7 family.

42514:efnb2b
gene id: 42514:efnb2b
uniprot id: A0A3B4DCQ8
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:atp11a
gene id: 42514:atp11a
uniprot id: A0A3B4D3R5
uniprot id: A0A3B4EED0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

42514:slc15a1b
gene id: 42514:slc15a1b
uniprot id: A0A3B4CJ51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

42514:ipmkb
gene id: 42514:ipmkb
uniprot id: A0A3B4E715
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

42514:slc20a2
gene id: 42514:slc20a2
uniprot id: A0A3B4C267
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

42514:zgc:65851
gene id: 42514:zgc:65851
uniprot id: A0A3B4BPL5
names: Similarity
messages: Belongs to the intermediate filament family.

42514:LOC108434265
gene id: 42514:LOC108434265
uniprot id: A0A3B4BWZ9
names: Subcellular Location Annotation
messages: Membrane

42514:spice1
gene id: 42514:spice1
uniprot id: A0A3B4EA08
names: Subcellular Location Annotation
messages: centriole
messages: spindle

42514:LOC108431779
gene id: 42514:LOC108431779
uniprot id: A0A3B4CQ19
names: Similarity
messages: Belongs to the NipSnap family.

42514:adcy5
gene id: 42514:adcy5
uniprot id: A0A3B4EM47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

42514:ampd3a
gene id: 42514:ampd3a
uniprot id: A0A3B4DYV0
uniprot id: A0A3B4E057
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

42514:vps35l
gene id: 42514:vps35l
uniprot id: A0A3B4DA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

42514:dnmt1
gene id: 42514:dnmt1
uniprot id: A0A3B4CJF5
uniprot id: A0A3B4E434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

42514:c8g
gene id: 42514:c8g
uniprot id: A0A3B4CMX7
names: Subcellular Location Annotation
messages: Secreted

42514:arl5c
gene id: 42514:arl5c
uniprot id: A0A3B4C659
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

42514:prune
gene id: 42514:prune
uniprot id: A0A3B4D6P9
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

42514:acox3
gene id: 42514:acox3
uniprot id: A0A3B4C3J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

42514:nup85
gene id: 42514:nup85
uniprot id: A0A3B4DZN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

42514:arid5b
gene id: 42514:arid5b
uniprot id: A0A3B4CN43
names: Similarity
messages: Belongs to the ARID5B family.

42514:kcnk18
gene id: 42514:kcnk18
uniprot id: A0A3B4EF50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:smek1
gene id: 42514:smek1
uniprot id: A0A3B4E589
names: Similarity
messages: Belongs to the SMEK family.

42514:ssh1a
gene id: 42514:ssh1a
uniprot id: A0A3B4C4N5
uniprot id: A0A3B4DQ00
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

42514:serpinh1a
gene id: 42514:serpinh1a
uniprot id: A0A3B4CDX7
names: Similarity
messages: Belongs to the serpin family.

42514:slc52a3
gene id: 42514:slc52a3
uniprot id: A0A3B4E7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

42514:LOC108438467
gene id: 42514:LOC108438467
uniprot id: A0A3B4E875
uniprot id: A0A3B4E9E7
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

42514:slc5a8l
gene id: 42514:slc5a8l
uniprot id: A0A3B4BXG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:ccdc124
gene id: 42514:ccdc124
uniprot id: A0A3B4EJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC124 family.
messages: Midbody

42514:LOC108415169
gene id: 42514:LOC108415169
uniprot id: A0A3B4D167
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:hnrnph1
gene id: 42514:hnrnph1
uniprot id: A0A3B4DJA6
names: Subcellular Location Annotation
messages: nucleoplasm

42514:nrn1la
gene id: 42514:nrn1la
uniprot id: A0A3B4E8E2
names: Similarity
messages: Belongs to the neuritin family.

42514:vdra
gene id: 42514:vdra
uniprot id: A0A3B4D261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

42514:nkx2.1
gene id: 42514:nkx2.1
uniprot id: A0A3B4CHS1
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108435245
gene id: 42514:LOC108435245
uniprot id: A0A3B4CDU1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

42514:osbpl10b
gene id: 42514:osbpl10b
uniprot id: A0A3B4DRL5
names: Similarity
messages: Belongs to the OSBP family.

42514:en1b
gene id: 42514:en1b
uniprot id: A0A3B4DP41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

42514:spc25
gene id: 42514:spc25
uniprot id: A0A3B4D0H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

42514:zhx2a
gene id: 42514:zhx2a
uniprot id: A0A3B4D6K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

42514:LOC108431906
gene id: 42514:LOC108431906
uniprot id: A0A3B4C677
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:ptpn11a
gene id: 42514:ptpn11a
uniprot id: A0A3B4C7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

42514:sulf1
gene id: 42514:sulf1
uniprot id: A0A3B4CPX6
uniprot id: A0A3B4E7R2
uniprot id: A0A3B4E8Y1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

42514:alg12
gene id: 42514:alg12
uniprot id: A0A3B4DFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108410903
gene id: 42514:LOC108410903
uniprot id: A0A3B4EPS7
names: Similarity
messages: Belongs to the cyclin family.

42514:lnpa
gene id: 42514:lnpa
uniprot id: A0A3B4CX90
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

42514:slc35f1
gene id: 42514:slc35f1
uniprot id: A0A3B4DY92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

42514:cry3b
gene id: 42514:cry3b
uniprot id: A0A3B4DXC8
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

42514:LOC108433019
gene id: 42514:LOC108433019
uniprot id: A0A3B4DX93
names: Similarity
messages: Belongs to the cytochrome b5 family.

42514:LOC108423506
gene id: 42514:LOC108423506
uniprot id: A0A3B4BXL4
names: Similarity
messages: Belongs to the IFT43 family.

42514:LOC108413992
gene id: 42514:LOC108413992
uniprot id: A0A3B4BTN6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:tle5
gene id: 42514:tle5
uniprot id: A0A3B4CMK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

42514:sugct
gene id: 42514:sugct
uniprot id: A0A3B4DJ47
names: Similarity
messages: Belongs to the CoA-transferase III family.

42514:rorcb
gene id: 42514:rorcb
uniprot id: A0A3B4DTX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:adam23a
gene id: 42514:adam23a
uniprot id: A0A3B4BRZ8
uniprot id: A0A3B4BV74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:bmp4
gene id: 42514:bmp4
uniprot id: A0A3B4BR28
names: Similarity
messages: Belongs to the TGF-beta family.

42514:mboat1
gene id: 42514:mboat1
uniprot id: A0A3B4DQY9
names: Subcellular Location Annotation
messages: Membrane

42514:kcnk4a
gene id: 42514:kcnk4a
uniprot id: A0A3B4ELN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:ckbb
gene id: 42514:ckbb
uniprot id: A0A3B4EMK0
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

42514:gngt2a
gene id: 42514:gngt2a
uniprot id: A0A3B4CJ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

42514:rad9a
gene id: 42514:rad9a
uniprot id: A0A3B4EJ68
names: Similarity
messages: Belongs to the rad9 family.

42514:ngfrb
gene id: 42514:ngfrb
uniprot id: A0A3B4D8Q7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:lsm1
gene id: 42514:lsm1
uniprot id: A0A3B4DYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

42514:zgc:153916
gene id: 42514:zgc:153916
uniprot id: A0A3B4BSU7
uniprot id: A0A3B4DJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

42514:mmp2
gene id: 42514:mmp2
uniprot id: A0A3B4EE34
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

42514:rdh12l
gene id: 42514:rdh12l
uniprot id: A0A3B4EDR1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:prdm8
gene id: 42514:prdm8
uniprot id: A0A3B4BLK6
names: Subcellular Location Annotation
messages: Nucleus

42514:slc35c1
gene id: 42514:slc35c1
uniprot id: A0A3B4DB34
names: Subcellular Location Annotation
messages: Membrane

42514:pbx3a
gene id: 42514:pbx3a
uniprot id: A0A3B4CWP9
uniprot id: A0A3B4CY91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

42514:sfrp1b
gene id: 42514:sfrp1b
uniprot id: A0A3B4EGZ7
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:idh1
gene id: 42514:idh1
uniprot id: A0A3B4EIQ1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

42514:slc25a39
gene id: 42514:slc25a39
uniprot id: A0A3B4DHK0
uniprot id: A0A3B4EP77
uniprot id: A0A3B4ER29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:LOC108441154
gene id: 42514:LOC108441154
uniprot id: A0A3B4CVU9
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

42514:oprd1b
gene id: 42514:oprd1b
uniprot id: A0A3B4EE81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:spata6l
gene id: 42514:spata6l
uniprot id: A0A3B4BXZ8
names: Similarity
messages: Belongs to the SPATA6 family.

42514:chrm2b
gene id: 42514:chrm2b
uniprot id: A0A3B4E714
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

42514:cldn15a
gene id: 42514:cldn15a
uniprot id: A0A3B4E9Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:csad
gene id: 42514:csad
uniprot id: A0A3B4ED67
names: Similarity
messages: Belongs to the group II decarboxylase family.

42514:slc15a2
gene id: 42514:slc15a2
uniprot id: A0A3B4EL94
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

42514:LOC108441900
gene id: 42514:LOC108441900
uniprot id: A0A3B4DWC1
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

42514:nfx1
gene id: 42514:nfx1
uniprot id: A0A3B4E476
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

42514:jak2a
gene id: 42514:jak2a
uniprot id: A0A3B4CLJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

42514:pter
gene id: 42514:pter
uniprot id: A0A3B4DU40
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tmem30c
gene id: 42514:tmem30c
uniprot id: A0A3B4BMN9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

42514:LOC108439629
gene id: 42514:LOC108439629
uniprot id: A0A3B4DY86
names: Similarity
messages: Belongs to the GADD45 family.

42514:LOC108438687
gene id: 42514:LOC108438687
uniprot id: A0A3B4DVK4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:cltcl1
gene id: 42514:cltcl1
uniprot id: A0A3B4BSE2
uniprot id: A0A3B4DMQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

42514:six9
gene id: 42514:six9
uniprot id: A0A3B4E9C9
names: Subcellular Location Annotation
messages: Nucleus

42514:dync1i2b
gene id: 42514:dync1i2b
uniprot id: A0A3B4C062
uniprot id: A0A3B4DRU0
names: Similarity
messages: Belongs to the dynein intermediate chain family.

42514:tes
gene id: 42514:tes
uniprot id: A0A3B4ELB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

42514:hnrnpaba
gene id: 42514:hnrnpaba
uniprot id: A0A3B4DJX8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:LOC108438287
gene id: 42514:LOC108438287
uniprot id: A0A3B4EL22
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:akt2
gene id: 42514:akt2
uniprot id: A0A3B4DSP1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

42514:tmem170b
gene id: 42514:tmem170b
uniprot id: A0A3B4BSS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

42514:ddx49
gene id: 42514:ddx49
uniprot id: A0A3B4E2X9
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:rps6ka2
gene id: 42514:rps6ka2
uniprot id: A0A3B4D8Y7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

42514:LOC108430993
gene id: 42514:LOC108430993
uniprot id: A0A3B4DQ74
names: Similarity
messages: Belongs to the SLT11 family.

42514:mrpl46
gene id: 42514:mrpl46
uniprot id: A0A3B4C962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

42514:mboat7
gene id: 42514:mboat7
uniprot id: A0A3B4E1N1
names: Subcellular Location Annotation
messages: Membrane

42514:atp2a1l
gene id: 42514:atp2a1l
uniprot id: A0A3B4D2F0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

42514:LOC108424594
gene id: 42514:LOC108424594
uniprot id: A0A3B4DIZ6
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

42514:si:ch73-116o1.2
gene id: 42514:si:ch73-116o1.2
uniprot id: A0A3B4D968
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:kdm2aa
gene id: 42514:kdm2aa
uniprot id: A0A3B4CD92
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

42514:LOC108440009
gene id: 42514:LOC108440009
uniprot id: A0A3B4CXQ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:dyrk1ab
gene id: 42514:dyrk1ab
uniprot id: A0A3B4C838
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

42514:sirt2
gene id: 42514:sirt2
uniprot id: A0A3B4DUM1
uniprot id: A0A3B4DVS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

42514:fgd
gene id: 42514:fgd
uniprot id: A0A3B4E8B4
names: Subcellular Location Annotation
messages: cytoskeleton

42514:LOC108414196
gene id: 42514:LOC108414196
uniprot id: A0A3B4DEB4
uniprot id: A0A3B4DH30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:cdk5r2a
gene id: 42514:cdk5r2a
uniprot id: A0A3B4EBM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

42514:LOC108430668
gene id: 42514:LOC108430668
uniprot id: A0A3B4CSX3
names: Similarity
messages: Belongs to the actin family.

42514:atxn1b
gene id: 42514:atxn1b
uniprot id: A0A3B4DLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

42514:cab39l1
gene id: 42514:cab39l1
uniprot id: A0A3B4CU59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

42514:pmvk
gene id: 42514:pmvk
uniprot id: A0A3B4DQW5
names: Subcellular Location Annotation
messages: cytosol

42514:derl1
gene id: 42514:derl1
uniprot id: A0A3B4DAF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

42514:kcnq2a
gene id: 42514:kcnq2a
uniprot id: A0A3B4D2T8
uniprot id: A0A3B4EEW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:eif4e1c
gene id: 42514:eif4e1c
uniprot id: A0A3B4DAX8
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

42514:LOC108413118
gene id: 42514:LOC108413118
uniprot id: A0A3B4DPC3
names: Similarity
messages: Belongs to the intermediate filament family.

42514:si:dkey-239n17.4
gene id: 42514:si:dkey-239n17.4
uniprot id: A0A3B4DF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:LOC108430658
gene id: 42514:LOC108430658
uniprot id: A0A3B4CSJ0
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:g6pd
gene id: 42514:g6pd
uniprot id: A0A3B4CSW1
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.

42514:ugp2b
gene id: 42514:ugp2b
uniprot id: A0A3B4D8Q1
uniprot id: A0A3B4EH01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

42514:rxrga
gene id: 42514:rxrga
uniprot id: A0A3B4E7V5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

42514:atp6ap1b
gene id: 42514:atp6ap1b
uniprot id: A0A3B4CPB4
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

42514:en1a
gene id: 42514:en1a
uniprot id: A0A3B4D407
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

42514:wnt8a
gene id: 42514:wnt8a
uniprot id: A0A3B4CU04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:LOC108424051
gene id: 42514:LOC108424051
uniprot id: A0A3B4BYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:s100a10b
gene id: 42514:s100a10b
uniprot id: A0A3B4EMZ5
names: Similarity
messages: Belongs to the S-100 family.

42514:smc3
gene id: 42514:smc3
uniprot id: A0A3B4DXM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

42514:ppp3r1b
gene id: 42514:ppp3r1b
uniprot id: A0A3B4E629
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

42514:arl5a
gene id: 42514:arl5a
uniprot id: A0A3B4CNF7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

42514:ndufa3
gene id: 42514:ndufa3
uniprot id: A0A3B4E4X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane

42514:nfkb1
gene id: 42514:nfkb1
uniprot id: A0A3B4DR72
uniprot id: A0A3B4DV88
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:tlcd5b
gene id: 42514:tlcd5b
uniprot id: A0A3B4E120
names: Subcellular Location Annotation
messages: Membrane

42514:clk4b
gene id: 42514:clk4b
uniprot id: A0A3B4DEJ6
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:parp12b
gene id: 42514:parp12b
uniprot id: A0A3B4DKB2
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:tmem54b
gene id: 42514:tmem54b
uniprot id: A0A3B4DMW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

42514:LOC108423484
gene id: 42514:LOC108423484
uniprot id: A0A3B4BWX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

42514:uckl1a
gene id: 42514:uckl1a
uniprot id: A0A3B4C5X2
uniprot id: A0A3B4DV77
names: Similarity
messages: Belongs to the uridine kinase family.

42514:aprt
gene id: 42514:aprt
uniprot id: A0A3B4CTV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

42514:nap1l4a
gene id: 42514:nap1l4a
uniprot id: A0A3B4BWH0
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

42514:adam15
gene id: 42514:adam15
uniprot id: A0A3B4BNK4
uniprot id: A0A3B4DJ41
uniprot id: A0A3B4DK14
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dennd10
gene id: 42514:dennd10
uniprot id: A0A3B4C1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

42514:wasb
gene id: 42514:wasb
uniprot id: A0A3B4CM13
names: Subcellular Location Annotation
messages: Nucleus

42514:map3k12
gene id: 42514:map3k12
uniprot id: A0A3B4DTL3
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: May be an activator of the JNK/SAPK pathway.

42514:hspa5
gene id: 42514:hspa5
uniprot id: A0A3B4EKE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

42514:smarcd2
gene id: 42514:smarcd2
uniprot id: A0A3B4C4Q3
names: Similarity
messages: Belongs to the SMARCD family.

42514:lpcat2
gene id: 42514:lpcat2
uniprot id: A0A3B4D547
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:smad5
gene id: 42514:smad5
uniprot id: A0A3B4D5B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:c29h9orf64
gene id: 42514:c29h9orf64
uniprot id: A0A3B4E427
names: Function
names: Similarity
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.

42514:tspan33a
gene id: 42514:tspan33a
uniprot id: A0A3B4BTX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:dnajc2
gene id: 42514:dnajc2
uniprot id: A0A3B4E5B1
names: Subcellular Location Annotation
messages: cytosol

42514:tmem214
gene id: 42514:tmem214
uniprot id: A0A3B4CV71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:sgtb
gene id: 42514:sgtb
uniprot id: A0A3B4DKY7
names: Similarity
messages: Belongs to the SGT family.

42514:acad9
gene id: 42514:acad9
uniprot id: A0A3B4DHE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

42514:rpe
gene id: 42514:rpe
uniprot id: A0A3B4DJT3
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

42514:LOC108433266
gene id: 42514:LOC108433266
uniprot id: A0A3B4DGH8
uniprot id: A0A3B4DH20
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

42514:LOC108425965
gene id: 42514:LOC108425965
uniprot id: A0A3B4DCR1
names: Subcellular Location Annotation
messages: Cytoplasm

42514:ocrl
gene id: 42514:ocrl
uniprot id: A0A3B4EBM7
uniprot id: A0A3B4EBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

42514:hoxa13a
gene id: 42514:hoxa13a
uniprot id: A0A3B4BMZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

42514:zgc:103559
gene id: 42514:zgc:103559
uniprot id: A0A3B4DBS4
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Homotetramer.

42514:polr1d
gene id: 42514:polr1d
uniprot id: A0A3B4BYI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

42514:fxyd7
gene id: 42514:fxyd7
uniprot id: A0A3B4EI20
names: Similarity
messages: Belongs to the FXYD family.

42514:cd81a
gene id: 42514:cd81a
uniprot id: A0A3B4DXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:smpdl3b
gene id: 42514:smpdl3b
uniprot id: A0A3B4CEC0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

42514:stmn2b
gene id: 42514:stmn2b
uniprot id: A0A3B4DP59
names: Similarity
messages: Belongs to the stathmin family.

42514:pold2
gene id: 42514:pold2
uniprot id: A0A3B4EE50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

42514:galk2
gene id: 42514:galk2
uniprot id: A0A3B4CCB2
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

42514:hdac5
gene id: 42514:hdac5
uniprot id: A0A3B4CMG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

42514:casp23
gene id: 42514:casp23
uniprot id: A0A3B4C1Z8
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:LOC108441115
gene id: 42514:LOC108441115
uniprot id: A0A3B4EG16
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108437766
gene id: 42514:LOC108437766
uniprot id: A0A3B4D3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:ddit4
gene id: 42514:ddit4
uniprot id: A0A3B4BRC9
names: Similarity
messages: Belongs to the DDIT4 family.

42514:fam199x
gene id: 42514:fam199x
uniprot id: A0A3B4D030
names: Similarity
messages: Belongs to the FAM199 family.

42514:LOC108431958
gene id: 42514:LOC108431958
uniprot id: A0A3B4C0L1
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

42514:LOC108434724
gene id: 42514:LOC108434724
uniprot id: A0A3B4CF76
names: Similarity
messages: Belongs to the chondromodulin-1 family.

42514:tlx1
gene id: 42514:tlx1
uniprot id: A0A3B4BUE6
names: Subcellular Location Annotation
messages: Nucleus

42514:impa2
gene id: 42514:impa2
uniprot id: A0A3B4DL42
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

42514:enpp1
gene id: 42514:enpp1
uniprot id: A0A3B4CCE6
names: Subcellular Location Annotation
messages: Secreted

42514:man1b1a
gene id: 42514:man1b1a
uniprot id: A0A3B4ENE2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

42514:bco1
gene id: 42514:bco1
uniprot id: A0A3B4E0M9
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

42514:rcan2
gene id: 42514:rcan2
uniprot id: A0A3B4BR27
uniprot id: A0A3B4DJR8
names: Function
names: Similarity
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

42514:adcy8
gene id: 42514:adcy8
uniprot id: A0A3B4E9M7
uniprot id: A0A3B4EBG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

42514:hsph1
gene id: 42514:hsph1
uniprot id: A0A3B4DMM2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:LOC108435101
gene id: 42514:LOC108435101
uniprot id: A0A3B4C6C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:aass
gene id: 42514:aass
uniprot id: A0A3B4CGZ1
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

42514:cdc42bpab
gene id: 42514:cdc42bpab
uniprot id: A0A3B4BUB4
uniprot id: A0A3B4DI60
uniprot id: A0A3B4DKU2
uniprot id: A0A3B4DM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: lamellipodium

42514:foxj1a
gene id: 42514:foxj1a
uniprot id: A0A3B4D118
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FOXJ1 family.
messages: Nucleus

42514:cebpa
gene id: 42514:cebpa
uniprot id: A0A3B4EG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

42514:map2k1
gene id: 42514:map2k1
uniprot id: A0A3B4CCA7
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:timm17a
gene id: 42514:timm17a
uniprot id: A0A3B4CF60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

42514:minar1
gene id: 42514:minar1
uniprot id: A0A3B4C3Y7
names: Similarity
messages: Belongs to the MINAR family.

42514:dennd5b
gene id: 42514:dennd5b
uniprot id: A0A3B4CK41
uniprot id: A0A3B4CK92
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108429155
gene id: 42514:LOC108429155
uniprot id: A0A3B4ES35
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

42514:rbpjb
gene id: 42514:rbpjb
uniprot id: A0A3B4C2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

42514:nell2a
gene id: 42514:nell2a
uniprot id: A0A3B4E276
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:pgam1a
gene id: 42514:pgam1a
uniprot id: A0A3B4BPV8
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

42514:vamp1
gene id: 42514:vamp1
uniprot id: A0A3B4DXA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

42514:bmp7b
gene id: 42514:bmp7b
uniprot id: A0A3B4DR98
names: Similarity
messages: Belongs to the TGF-beta family.

42514:naf1
gene id: 42514:naf1
uniprot id: A0A3B4BS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

42514:vcla
gene id: 42514:vcla
uniprot id: A0A3B4CAH2
uniprot id: A0A3B4CCC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: podosome

42514:uroc1
gene id: 42514:uroc1
uniprot id: A0A3B4E091
names: Similarity
messages: Belongs to the urocanase family.

42514:LOC108427772
gene id: 42514:LOC108427772
uniprot id: A0A3B4EG04
names: Similarity
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.

42514:ngly1
gene id: 42514:ngly1
uniprot id: A0A3B4CXF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Cytoplasm
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.

42514:slc29a4
gene id: 42514:slc29a4
uniprot id: A0A3B4D0I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

42514:snx5
gene id: 42514:snx5
uniprot id: A0A3B4CKX0
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

42514:banf1
gene id: 42514:banf1
uniprot id: A0A3B4DRR7
names: Subcellular Location Annotation
messages: Nucleus

42514:unc119.1
gene id: 42514:unc119.1
uniprot id: A0A3B4ELJ0
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

42514:clcn5b
gene id: 42514:clcn5b
uniprot id: A0A3B4DXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

42514:mocs3
gene id: 42514:mocs3
uniprot id: A0A3B4CHE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

42514:LOC108413169
gene id: 42514:LOC108413169
uniprot id: A0A3B4BV47
uniprot id: A0A3B4DMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

42514:acp7
gene id: 42514:acp7
uniprot id: A0A3B4CUR1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

42514:slc25a16
gene id: 42514:slc25a16
uniprot id: A0A3B4EME5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:hnrnpa1b
gene id: 42514:hnrnpa1b
uniprot id: A0A3B4CTX8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:LOC108430776
gene id: 42514:LOC108430776
uniprot id: A0A3B4E2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:pfas
gene id: 42514:pfas
uniprot id: A0A3B4DKZ7
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

42514:mark2b
gene id: 42514:mark2b
uniprot id: A0A3B4CNE9
uniprot id: A0A3B4E855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

42514:gria1a
gene id: 42514:gria1a
uniprot id: A0A3B4E9D8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:b3gnt2a
gene id: 42514:b3gnt2a
uniprot id: A0A3B4CB49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:irg1l
gene id: 42514:irg1l
uniprot id: A0A3B4E8E6
names: Similarity
messages: Belongs to the PrpD family.

42514:eif4ebp1
gene id: 42514:eif4ebp1
uniprot id: A0A3B4E340
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

42514:cldn7b
gene id: 42514:cldn7b
uniprot id: A0A3B4ELY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:LOC108430332
gene id: 42514:LOC108430332
uniprot id: A0A3B4DKL8
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

42514:zgc:165583
gene id: 42514:zgc:165583
uniprot id: A0A3B4CAY6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108428727
gene id: 42514:LOC108428727
uniprot id: A0A3B4DIS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:nipal3
gene id: 42514:nipal3
uniprot id: A0A3B4BUP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

42514:rhot1b
gene id: 42514:rhot1b
uniprot id: A0A3B4DBE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

42514:atp11c
gene id: 42514:atp11c
uniprot id: A0A3B4CS09
uniprot id: A0A3B4E4V3
uniprot id: A0A3B4E7B3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108424293
gene id: 42514:LOC108424293
uniprot id: A0A3B4CGS3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:LOC108410407
gene id: 42514:LOC108410407
uniprot id: A0A3B4EG53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 7B2 family.
messages: Secreted

42514:LOC108436879
gene id: 42514:LOC108436879
uniprot id: A0A3B4CHX8
names: Similarity
messages: Belongs to the TTC39 family.

42514:sumo3a
gene id: 42514:sumo3a
uniprot id: A0A3B4DVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

42514:cab39l
gene id: 42514:cab39l
uniprot id: A0A3B4D5C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

42514:anxa13
gene id: 42514:anxa13
uniprot id: A0A3B4DHF4
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

42514:LOC108429163
gene id: 42514:LOC108429163
uniprot id: A0A3B4CCC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

42514:epha6
gene id: 42514:epha6
uniprot id: A0A3B4D3W2
uniprot id: A0A3B4EH78
names: Subcellular Location Annotation
messages: Membrane

42514:si:dkey-190g11.3
gene id: 42514:si:dkey-190g11.3
uniprot id: A0A3B4CC84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

42514:il6st
gene id: 42514:il6st
uniprot id: A0A3B4CTI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

42514:LOC108412813
gene id: 42514:LOC108412813
uniprot id: A0A3B4CKV2
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

42514:LOC108435466
gene id: 42514:LOC108435466
uniprot id: A0A3B4DFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:LOC108426917
gene id: 42514:LOC108426917
uniprot id: A0A3B4DLA1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:chmp1a
gene id: 42514:chmp1a
uniprot id: A0A3B4CLV6
names: Similarity
messages: Belongs to the SNF7 family.

42514:pcnx2
gene id: 42514:pcnx2
uniprot id: A0A3B4DF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

42514:cahz
gene id: 42514:cahz
uniprot id: A0A3B4D1A6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

42514:khdc4
gene id: 42514:khdc4
uniprot id: A0A3B4CZK9
names: Similarity
messages: Belongs to the KHDC4 family.

42514:LOC108442750
gene id: 42514:LOC108442750
uniprot id: A0A3B4DGQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:rnf8
gene id: 42514:rnf8
uniprot id: A0A3B4C2C8
names: Similarity
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.

42514:pard3aa
gene id: 42514:pard3aa
uniprot id: A0A3B4BRI4
uniprot id: A0A3B4DG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

42514:ip6k1
gene id: 42514:ip6k1
uniprot id: A0A3B4EML2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

42514:LOC108437340
gene id: 42514:LOC108437340
uniprot id: A0A3B4EEP7
uniprot id: A0A3B4EEQ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:top3b
gene id: 42514:top3b
uniprot id: A0A3B4CVT6
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

42514:oxa1l
gene id: 42514:oxa1l
uniprot id: A0A3B4C5N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

42514:pycr3
gene id: 42514:pycr3
uniprot id: A0A3B4BRA9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

42514:sparcl1
gene id: 42514:sparcl1
uniprot id: A0A3B4E645
names: Similarity
messages: Belongs to the SPARC family.

42514:LOC108432603
gene id: 42514:LOC108432603
uniprot id: A0A3B4DJ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:gins2
gene id: 42514:gins2
uniprot id: A0A3B4EMR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

42514:sybl1
gene id: 42514:sybl1
uniprot id: A0A3B4DN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

42514:gsx2
gene id: 42514:gsx2
uniprot id: A0A3B4DND0
names: Subcellular Location Annotation
messages: Nucleus

42514:abitram
gene id: 42514:abitram
uniprot id: A0A3B4DKP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

42514:oxsr1b
gene id: 42514:oxsr1b
uniprot id: A0A3B4CQM8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

42514:eif4a1a
gene id: 42514:eif4a1a
uniprot id: A0A3B4D9S3
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

42514:tspan9b
gene id: 42514:tspan9b
uniprot id: A0A3B4BYB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:tssc4
gene id: 42514:tssc4
uniprot id: A0A3B4CFP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TSSC4 family.
messages: Cytoplasm
messages: Nucleus

42514:stoml1
gene id: 42514:stoml1
uniprot id: A0A3B4BQ93
names: Similarity
messages: Belongs to the band 7/mec-2 family.

42514:LOC108425558
gene id: 42514:LOC108425558
uniprot id: A0A3B4CSW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

42514:grem2a
gene id: 42514:grem2a
uniprot id: A0A3B4EKJ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:adam17a
gene id: 42514:adam17a
uniprot id: A0A3B4CJR4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:slc4a2b
gene id: 42514:slc4a2b
uniprot id: A0A3B4EF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

42514:znf830
gene id: 42514:znf830
uniprot id: A0A3B4E3S2
names: Subcellular Location Annotation
messages: Nucleus

42514:wdr35
gene id: 42514:wdr35
uniprot id: A0A3B4DQ06
names: Subcellular Location Annotation
messages: centrosome
messages: cilium basal body

42514:hapln1a
gene id: 42514:hapln1a
uniprot id: A0A3B4DWG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:cct6a
gene id: 42514:cct6a
uniprot id: A0A3B4CMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

42514:hyal6
gene id: 42514:hyal6
uniprot id: A0A3B4CH52
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

42514:ptdss1a
gene id: 42514:ptdss1a
uniprot id: A0A3B4DJC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:mfsd8
gene id: 42514:mfsd8
uniprot id: A0A3B4BZJ0
names: Subcellular Location Annotation
messages: Membrane

42514:cep70
gene id: 42514:cep70
uniprot id: A0A3B4CWU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

42514:chrnb3b
gene id: 42514:chrnb3b
uniprot id: A0A3B4DFZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:f3b
gene id: 42514:f3b
uniprot id: A0A3B4DT78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

42514:LOC108434294
gene id: 42514:LOC108434294
uniprot id: A0A3B4DMK2
names: Similarity
messages: Belongs to the MHC class I family.

42514:orc2
gene id: 42514:orc2
uniprot id: A0A3B4BRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

42514:tmem208
gene id: 42514:tmem208
uniprot id: A0A3B4DK45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane

42514:hmgcrb
gene id: 42514:hmgcrb
uniprot id: A0A3B4BYL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

42514:LOC108434972
gene id: 42514:LOC108434972
uniprot id: A0A3B4DDL2
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

42514:erg28
gene id: 42514:erg28
uniprot id: A0A3B4DKE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:asf1bb
gene id: 42514:asf1bb
uniprot id: A0A3B4D3T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

42514:arhgef6
gene id: 42514:arhgef6
uniprot id: A0A3B4CP13
names: Subcellular Location Annotation
messages: lamellipodium

42514:dhrs13a.2
gene id: 42514:dhrs13a.2
uniprot id: A0A3B4DAB9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:anapc10
gene id: 42514:anapc10
uniprot id: A0A3B4BRM7
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

42514:esrrb
gene id: 42514:esrrb
uniprot id: A0A3B4BUL9
uniprot id: A0A3B4BXR3
uniprot id: A0A3B4DNB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

42514:asic1c
gene id: 42514:asic1c
uniprot id: A0A3B4CCS1
uniprot id: A0A3B4CEJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:mcrip1
gene id: 42514:mcrip1
uniprot id: A0A3B4DVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

42514:LOC108443875
gene id: 42514:LOC108443875
uniprot id: A0A3B4BPQ4
names: Subcellular Location Annotation
messages: Membrane

42514:s1pr5b
gene id: 42514:s1pr5b
uniprot id: A0A3B4BP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:gpr37a
gene id: 42514:gpr37a
uniprot id: A0A3B4E3V9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:faslg
gene id: 42514:faslg
uniprot id: A0A3B4BNA7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:mgme1
gene id: 42514:mgme1
uniprot id: A0A3B4CKU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGME1 family.
messages: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair.
messages: Mitochondrion

42514:mtif3
gene id: 42514:mtif3
uniprot id: A0A3B4EPL0
names: Similarity
messages: Belongs to the IF-3 family.

42514:med19a
gene id: 42514:med19a
uniprot id: A0A3B4D7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:LOC108437822
gene id: 42514:LOC108437822
uniprot id: A0A3B4CS44
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108434690
gene id: 42514:LOC108434690
uniprot id: A0A3B4E4V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

42514:si:ch73-233f7.1
gene id: 42514:si:ch73-233f7.1
uniprot id: A0A3B4DST7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

42514:trim2a
gene id: 42514:trim2a
uniprot id: A0A3B4BTH1
names: Similarity
messages: Belongs to the TRIM/RBCC family.

42514:ppp2r2bb
gene id: 42514:ppp2r2bb
uniprot id: A0A3B4DAY7
uniprot id: A0A3B4DCL0
uniprot id: A0A3B4DCL6
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

42514:limk1a
gene id: 42514:limk1a
uniprot id: A0A3B4DGN6
uniprot id: A0A3B4DGP1
uniprot id: A0A3B4DKY8
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

42514:usp32
gene id: 42514:usp32
uniprot id: A0A3B4BYL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

42514:LOC108442714
gene id: 42514:LOC108442714
uniprot id: A0A3B4DHT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

42514:itk
gene id: 42514:itk
uniprot id: A0A3B4CVC4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:LOC108431959
gene id: 42514:LOC108431959
uniprot id: A0A3B4DDI0
names: Similarity
messages: Belongs to the SELO family.

42514:si:ch211-160d14.6
gene id: 42514:si:ch211-160d14.6
uniprot id: A0A3B4E199
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

42514:rfx3
gene id: 42514:rfx3
uniprot id: A0A3B4CTX4
uniprot id: A0A3B4E679
names: Subcellular Location Annotation
messages: Nucleus

42514:nusap1
gene id: 42514:nusap1
uniprot id: A0A3B4C7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

42514:kcng2
gene id: 42514:kcng2
uniprot id: A0A3B4D413
names: Subcellular Location Annotation
messages: Membrane

42514:a1cf
gene id: 42514:a1cf
uniprot id: A0A3B4DJ77
names: Subcellular Location Annotation
messages: Cytoplasm

42514:hkdc1
gene id: 42514:hkdc1
uniprot id: A0A3B4E5W3
names: Similarity
messages: Belongs to the hexokinase family.

42514:emc1
gene id: 42514:emc1
uniprot id: A0A3B4EF09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108436737
gene id: 42514:LOC108436737
uniprot id: A0A3B4ED85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

42514:sec13
gene id: 42514:sec13
uniprot id: A0A3B4D4I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

42514:ucn3l
gene id: 42514:ucn3l
uniprot id: A0A3B4DH42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

42514:LOC108434139
gene id: 42514:LOC108434139
uniprot id: A0A3B4C634
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:itpkca
gene id: 42514:itpkca
uniprot id: A0A3B4E4K2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

42514:cd44b
gene id: 42514:cd44b
uniprot id: A0A3B4EPB5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

42514:LOC108441468
gene id: 42514:LOC108441468
uniprot id: A0A3B4DRU3
names: Similarity
messages: Belongs to the FAM83 family.

42514:LOC108413871
gene id: 42514:LOC108413871
uniprot id: A0A3B4D412
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

42514:per2
gene id: 42514:per2
uniprot id: A0A3B4DD80
uniprot id: A0A3B4ELP9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:tpi1b
gene id: 42514:tpi1b
uniprot id: A0A3B4CT32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

42514:LOC108430149
gene id: 42514:LOC108430149
uniprot id: A0A3B4CAB7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

42514:mdka
gene id: 42514:mdka
uniprot id: A0A3B4EIS9
names: Similarity
messages: Belongs to the pleiotrophin family.

42514:fgg
gene id: 42514:fgg
uniprot id: A0A3B4BQ91
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

42514:guf1
gene id: 42514:guf1
uniprot id: A0A3B4D536
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

42514:parvaa
gene id: 42514:parvaa
uniprot id: A0A3B4BZK8
names: Similarity
messages: Belongs to the parvin family.

42514:cdkn1a
gene id: 42514:cdkn1a
uniprot id: A0A3B4DLX7
uniprot id: A0A3B4DPJ4
names: Similarity
messages: Belongs to the CDI family.

42514:LOC108411019
gene id: 42514:LOC108411019
uniprot id: A0A3B4EBD3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

42514:msx1a
gene id: 42514:msx1a
uniprot id: A0A3B4C6Y5
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108427257
gene id: 42514:LOC108427257
uniprot id: A0A3B4CPU1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:mks1
gene id: 42514:mks1
uniprot id: A0A3B4DZ91
names: Subcellular Location Annotation
messages: cilium basal body

42514:tmem170a
gene id: 42514:tmem170a
uniprot id: A0A3B4CJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

42514:sgk2a
gene id: 42514:sgk2a
uniprot id: A0A3B4D204
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108414035
gene id: 42514:LOC108414035
uniprot id: A0A3B4BL09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

42514:phykpl
gene id: 42514:phykpl
uniprot id: A0A3B4D425
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

42514:LOC108436676
gene id: 42514:LOC108436676
uniprot id: A0A3B4D8N9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:npy
gene id: 42514:npy
uniprot id: A0A3B4BQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

42514:LOC108429846
gene id: 42514:LOC108429846
uniprot id: A0A3B4BZZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

42514:epha4a
gene id: 42514:epha4a
uniprot id: A0A3B4CVI0
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

42514:wasla
gene id: 42514:wasla
uniprot id: A0A3B4CIG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: cytoskeleton

42514:odad4
gene id: 42514:odad4
uniprot id: A0A3B4DE83
names: Subcellular Location Annotation
messages: cilium axoneme

42514:snx10a
gene id: 42514:snx10a
uniprot id: A0A3B4BRF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

42514:LOC108444401
gene id: 42514:LOC108444401
uniprot id: A0A3B4BUY8
uniprot id: A0A3B4DLF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

42514:LOC108435474
gene id: 42514:LOC108435474
uniprot id: A0A3B4DF56
uniprot id: A0A3B4END0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

42514:flot1a
gene id: 42514:flot1a
uniprot id: A0A3B4BZL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

42514:ppa1a
gene id: 42514:ppa1a
uniprot id: A0A3B4BR81
names: Similarity
messages: Belongs to the PPase family.

42514:grhl2b
gene id: 42514:grhl2b
uniprot id: A0A3B4D3C0
names: Subcellular Location Annotation
messages: Nucleus

42514:cpdb
gene id: 42514:cpdb
uniprot id: A0A3B4E0W0
names: Similarity
messages: Belongs to the peptidase M14 family.

42514:prpf4bb
gene id: 42514:prpf4bb
uniprot id: A0A3B4CG04
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

42514:LOC108438432
gene id: 42514:LOC108438432
uniprot id: A0A3B4EE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:il17rc
gene id: 42514:il17rc
uniprot id: A0A3B4DMH5
names: Subcellular Location Annotation
messages: Membrane

42514:ube2t
gene id: 42514:ube2t
uniprot id: A0A3B4CV48
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:ganab
gene id: 42514:ganab
uniprot id: A0A3B4D065
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

42514:si:ch211-213o11.11
gene id: 42514:si:ch211-213o11.11
uniprot id: A0A3B4E2I3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:olfml2bb
gene id: 42514:olfml2bb
uniprot id: A0A3B4E941
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:peli2
gene id: 42514:peli2
uniprot id: A0A3B4CKD8
names: Similarity
messages: Belongs to the pellino family.

42514:LOC108437388
gene id: 42514:LOC108437388
uniprot id: A0A3B4EAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:dnph1
gene id: 42514:dnph1
uniprot id: A0A3B4C6F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus

42514:si:ch211-39i2.2
gene id: 42514:si:ch211-39i2.2
uniprot id: A0A3B4CMT8
names: Similarity
messages: Belongs to the DDIT4 family.

42514:foxf1
gene id: 42514:foxf1
uniprot id: A0A3B4DCQ6
names: Subcellular Location Annotation
messages: Nucleus

42514:sppl2
gene id: 42514:sppl2
uniprot id: A0A3B4DPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

42514:LOC108444451
gene id: 42514:LOC108444451
uniprot id: A0A3B4BP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

42514:mbpa
gene id: 42514:mbpa
uniprot id: A0A3B4CL54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

42514:ndufb11
gene id: 42514:ndufb11
uniprot id: A0A3B4EBD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:tp73
gene id: 42514:tp73
uniprot id: A0A3B4D941
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

42514:elavl1b
gene id: 42514:elavl1b
uniprot id: A0A3B4EHQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

42514:si:ch211-13f8.2
gene id: 42514:si:ch211-13f8.2
uniprot id: A0A3B4CLE4
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

42514:zdhhc6
gene id: 42514:zdhhc6
uniprot id: A0A3B4DCD4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:pptc7a
gene id: 42514:pptc7a
uniprot id: A0A3B4BMH4
names: Similarity
messages: Belongs to the PP2C family.

42514:plxna2
gene id: 42514:plxna2
uniprot id: A0A3B4CVY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108430042
gene id: 42514:LOC108430042
uniprot id: A0A3B4EGF1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:efemp2a
gene id: 42514:efemp2a
uniprot id: A0A3B4CT77
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ap3m2
gene id: 42514:ap3m2
uniprot id: A0A3B4CAA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus

42514:ficd
gene id: 42514:ficd
uniprot id: A0A3B4DTN5
names: Similarity
messages: Belongs to the fic family.

42514:adam10a
gene id: 42514:adam10a
uniprot id: A0A3B4EBH6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:nhsl1b
gene id: 42514:nhsl1b
uniprot id: A0A3B4CY58
uniprot id: A0A3B4CYY3
uniprot id: A0A3B4CYZ3
uniprot id: A0A3B4E9S4
uniprot id: A0A3B4EBQ1
uniprot id: A0A3B4EBT5
names: Similarity
messages: Belongs to the NHS family.

42514:pygl
gene id: 42514:pygl
uniprot id: A0A3B4C7E7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

42514:dhrs13b.1
gene id: 42514:dhrs13b.1
uniprot id: A0A3B4DPN6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:sema3ab
gene id: 42514:sema3ab
uniprot id: A0A3B4CXC5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:st18
gene id: 42514:st18
uniprot id: A0A3B4CJB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

42514:slc5a2
gene id: 42514:slc5a2
uniprot id: A0A3B4EID5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:runx2b
gene id: 42514:runx2b
uniprot id: A0A3B4E6I9
names: Subcellular Location Annotation
messages: Nucleus

42514:si:ch73-362m14.4
gene id: 42514:si:ch73-362m14.4
uniprot id: A0A3B4D4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

42514:rps26
gene id: 42514:rps26
uniprot id: A0A3B4EGA0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

42514:adam9
gene id: 42514:adam9
uniprot id: A0A3B4CAQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:psmb9a
gene id: 42514:psmb9a
uniprot id: A0A3B4BX78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

42514:urod
gene id: 42514:urod
uniprot id: A0A3B4CZ42
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

42514:esf1
gene id: 42514:esf1
uniprot id: A0A3B4CCC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

42514:cwc25
gene id: 42514:cwc25
uniprot id: A0A3B4DB14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

42514:esrrd
gene id: 42514:esrrd
uniprot id: A0A3B4CRM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

42514:snx20
gene id: 42514:snx20
uniprot id: A0A3B4BPF7
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

42514:agmat
gene id: 42514:agmat
uniprot id: A0A3B4CYA1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

42514:si:ch1073-157b13.1
gene id: 42514:si:ch1073-157b13.1
uniprot id: A0A3B4C5S9
names: Similarity
messages: Belongs to the methyltransferase superfamily.

42514:fut8a
gene id: 42514:fut8a
uniprot id: A0A3B4D5L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

42514:fam72a
gene id: 42514:fam72a
uniprot id: A0A3B4C2I7
names: Similarity
messages: Belongs to the FAM72 family.

42514:kcnj13
gene id: 42514:kcnj13
uniprot id: A0A3B4CDL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:eme1
gene id: 42514:eme1
uniprot id: A0A3B4C0R3
names: Similarity
messages: Belongs to the EME1/MMS4 family.

42514:LOC108430556
gene id: 42514:LOC108430556
uniprot id: A0A3B4EFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

42514:zgc:172302
gene id: 42514:zgc:172302
uniprot id: A0A3B4C1K4
names: Subcellular Location Annotation
messages: Membrane

42514:gal3st3
gene id: 42514:gal3st3
uniprot id: A0A3B4DQG5
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

42514:mgat5
gene id: 42514:mgat5
uniprot id: A0A3B4C8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

42514:LOC108414341
gene id: 42514:LOC108414341
uniprot id: A0A3B4DHW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

42514:l3mbtl2
gene id: 42514:l3mbtl2
uniprot id: A0A3B4E8J5
names: Subcellular Location Annotation
messages: Nucleus

42514:sebox
gene id: 42514:sebox
uniprot id: A0A3B4ELJ4
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108414840
gene id: 42514:LOC108414840
uniprot id: A0A3B4DYK3
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

42514:tmem18
gene id: 42514:tmem18
uniprot id: A0A3B4DDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

42514:rap1gds1
gene id: 42514:rap1gds1
uniprot id: A0A3B4BXS7
uniprot id: A0A3B4C155
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion

42514:phf19
gene id: 42514:phf19
uniprot id: A0A3B4D1J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

42514:LOC108412875
gene id: 42514:LOC108412875
uniprot id: A0A3B4CGU9
names: Similarity
messages: Belongs to the Bcl-2 family.

42514:rbm17
gene id: 42514:rbm17
uniprot id: A0A3B4EQ94
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

42514:LOC108430711
gene id: 42514:LOC108430711
uniprot id: A0A3B4E306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:def8
gene id: 42514:def8
uniprot id: A0A3B4ELV5
names: Similarity
messages: Belongs to the DEF8 family.

42514:LOC108428628
gene id: 42514:LOC108428628
uniprot id: A0A3B4BXK6
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108413039
gene id: 42514:LOC108413039
uniprot id: A0A3B4DWP4
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:cdkn3
gene id: 42514:cdkn3
uniprot id: A0A3B4CVT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

42514:arid3b
gene id: 42514:arid3b
uniprot id: A0A3B4E148
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer with ARID3A. Interacts with unphosphorylated RB1.
messages: Nucleus
messages: Transcription factor.

42514:vgll4a
gene id: 42514:vgll4a
uniprot id: A0A3B4CXN9
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

42514:mpped1
gene id: 42514:mpped1
uniprot id: A0A3B4BXY7
names: Similarity
messages: Belongs to the UPF0046 family.

42514:LOC108424161
gene id: 42514:LOC108424161
uniprot id: A0A3B4D4F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

42514:slc18b1
gene id: 42514:slc18b1
uniprot id: A0A3B4DJ29
names: Subcellular Location Annotation
messages: Membrane

42514:exoc5
gene id: 42514:exoc5
uniprot id: A0A3B4E3A9
names: Similarity
messages: Belongs to the SEC10 family.

42514:LOC108433259
gene id: 42514:LOC108433259
uniprot id: A0A3B4EGH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

42514:si:dkey-73n8.3
gene id: 42514:si:dkey-73n8.3
uniprot id: A0A3B4CNN5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:btbd10b
gene id: 42514:btbd10b
uniprot id: A0A3B4CB48
names: Subcellular Location Annotation
messages: Cytoplasm

42514:myoc
gene id: 42514:myoc
uniprot id: A0A3B4BRH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:rad52
gene id: 42514:rad52
uniprot id: A0A3B4E5G4
names: Similarity
messages: Belongs to the RAD52 family.

42514:LOC108432260
gene id: 42514:LOC108432260
uniprot id: A0A3B4EEE5
names: Similarity
messages: Belongs to the RBR family.

42514:nop58
gene id: 42514:nop58
uniprot id: A0A3B4CXY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

42514:si:ch211-225p5.8
gene id: 42514:si:ch211-225p5.8
uniprot id: A0A3B4CSN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

42514:LOC108443465
gene id: 42514:LOC108443465
uniprot id: A0A3B4CQE5
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:chmp2a
gene id: 42514:chmp2a
uniprot id: A0A3B4C9K3
names: Similarity
messages: Belongs to the SNF7 family.

42514:zgc:86609
gene id: 42514:zgc:86609
uniprot id: A0A3B4D1B6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

42514:LOC108438266
gene id: 42514:LOC108438266
uniprot id: A0A3B4EK84
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

42514:pcxb
gene id: 42514:pcxb
uniprot id: A0A3B4DSE5
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

42514:stxbp5l
gene id: 42514:stxbp5l
uniprot id: A0A3B4D2W4
uniprot id: A0A3B4D571
uniprot id: A0A3B4EFD8
uniprot id: A0A3B4EFE3
uniprot id: A0A3B4EHQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

42514:wnt9b
gene id: 42514:wnt9b
uniprot id: A0A3B4CJI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:prrx1b
gene id: 42514:prrx1b
uniprot id: A0A3B4ENB1
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108434828
gene id: 42514:LOC108434828
uniprot id: A0A3B4C571
names: Similarity
messages: Belongs to the cornifelin family.

42514:abraxas2
gene id: 42514:abraxas2
uniprot id: A0A3B4CVD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abro1 subfamily.
messages: Nucleus
messages: spindle pole

42514:egf
gene id: 42514:egf
uniprot id: A0A3B4CRP7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:slc35b1
gene id: 42514:slc35b1
uniprot id: A0A3B4DYS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

42514:LOC108433860
gene id: 42514:LOC108433860
uniprot id: A0A3B4DE43
names: Similarity
messages: Belongs to the MS4A family.

42514:gabrb4
gene id: 42514:gabrb4
uniprot id: A0A3B4D333
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:chrm2a
gene id: 42514:chrm2a
uniprot id: A0A3B4DAW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

42514:htra3a
gene id: 42514:htra3a
uniprot id: A0A3B4DZD1
names: Similarity
messages: Belongs to the peptidase S1C family.

42514:ssbp3b
gene id: 42514:ssbp3b
uniprot id: A0A3B4EFN4
names: Subcellular Location Annotation
messages: Nucleus

42514:qpctlb
gene id: 42514:qpctlb
uniprot id: A0A3B4CGJ2
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

42514:faxca
gene id: 42514:faxca
uniprot id: A0A3B4EEU8
names: Similarity
messages: Belongs to the FAX family.

42514:p2rx8
gene id: 42514:p2rx8
uniprot id: A0A3B4E832
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

42514:chmp5a
gene id: 42514:chmp5a
uniprot id: A0A3B4CQQ9
names: Similarity
messages: Belongs to the SNF7 family.

42514:stc2a
gene id: 42514:stc2a
uniprot id: A0A3B4BZ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

42514:tsen15
gene id: 42514:tsen15
uniprot id: A0A3B4CHB6
names: Similarity
messages: Belongs to the SEN15 family.

42514:rin3
gene id: 42514:rin3
uniprot id: A0A3B4D7Y3
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

42514:srxn1
gene id: 42514:srxn1
uniprot id: A0A3B4E7R6
names: Similarity
messages: Belongs to the sulfiredoxin family.

42514:wdr4
gene id: 42514:wdr4
uniprot id: A0A3B4E1K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat TRM82 family.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

42514:zgc:56493
gene id: 42514:zgc:56493
uniprot id: A0A3B4DXX8
names: Similarity
messages: Belongs to the thioredoxin family.

42514:kcnk13a
gene id: 42514:kcnk13a
uniprot id: A0A3B4EIU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:fgf8a
gene id: 42514:fgf8a
uniprot id: A0A3B4BU93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

42514:nbr1b
gene id: 42514:nbr1b
uniprot id: A0A3B4CAD6
names: Subcellular Location Annotation
messages: autophagosome

42514:fam83fb
gene id: 42514:fam83fb
uniprot id: A0A3B4EFX1
names: Similarity
messages: Belongs to the FAM83 family.

42514:rab3ab
gene id: 42514:rab3ab
uniprot id: A0A3B4E412
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

42514:phtf1
gene id: 42514:phtf1
uniprot id: A0A3B4DV74
names: Subcellular Location Annotation
messages: Membrane

42514:mrpl3
gene id: 42514:mrpl3
uniprot id: A0A3B4BPD6
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

42514:ssr4
gene id: 42514:ssr4
uniprot id: A0A3B4C4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

42514:s100t
gene id: 42514:s100t
uniprot id: A0A3B4DRG1
names: Similarity
messages: Belongs to the S-100 family.

42514:LOC108425627
gene id: 42514:LOC108425627
uniprot id: A0A3B4E5J7
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108413650
gene id: 42514:LOC108413650
uniprot id: A0A3B4E0L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

42514:LOC108415693
gene id: 42514:LOC108415693
uniprot id: A0A3B4EM49
names: Similarity
messages: Belongs to the cystatin family.

42514:rab18b
gene id: 42514:rab18b
uniprot id: A0A3B4DW63
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

42514:LOC108444070
gene id: 42514:LOC108444070
uniprot id: A0A3B4CZJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

42514:abcg4a
gene id: 42514:abcg4a
uniprot id: A0A3B4DS14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

42514:sar1b
gene id: 42514:sar1b
uniprot id: A0A3B4CCT7
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

42514:fam3c
gene id: 42514:fam3c
uniprot id: A0A3B4DJG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

42514:bpnt2
gene id: 42514:bpnt2
uniprot id: A0A3B4DDA4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

42514:LOC108441789
gene id: 42514:LOC108441789
uniprot id: A0A3B4CI92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

42514:nrn1lb
gene id: 42514:nrn1lb
uniprot id: A0A3B4CDQ5
names: Similarity
messages: Belongs to the neuritin family.

42514:med30
gene id: 42514:med30
uniprot id: A0A3B4D5D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

42514:unc5a
gene id: 42514:unc5a
uniprot id: A0A3B4DUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

42514:dhx15
gene id: 42514:dhx15
uniprot id: A0A3B4BZ48
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

42514:ufm1
gene id: 42514:ufm1
uniprot id: A0A3B4CKQ6
uniprot id: A0A3B4E4L7
names: Function
names: Similarity
messages: Belongs to the UFM1 family.
messages: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

42514:uxt
gene id: 42514:uxt
uniprot id: A0A3B4D1E3
names: Similarity
messages: Belongs to the UXT family.

42514:chmp2bb
gene id: 42514:chmp2bb
uniprot id: A0A3B4EI36
names: Similarity
messages: Belongs to the SNF7 family.

42514:inaa
gene id: 42514:inaa
uniprot id: A0A3B4DLJ6
names: Similarity
messages: Belongs to the intermediate filament family.

42514:vps16
gene id: 42514:vps16
uniprot id: A0A3B4EBZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS16 family.
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: Vesicle

42514:LOC108434843
gene id: 42514:LOC108434843
uniprot id: A0A3B4ENR9
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

42514:fmnl1b
gene id: 42514:fmnl1b
uniprot id: A0A3B4DVV2
uniprot id: A0A3B4DZX4
names: Similarity
messages: Belongs to the formin homology family.

42514:cdca5
gene id: 42514:cdca5
uniprot id: A0A3B4CZ55
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

42514:si:dkey-251i10.1
gene id: 42514:si:dkey-251i10.1
uniprot id: A0A3B4BLB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

42514:xpot
gene id: 42514:xpot
uniprot id: A0A3B4DM72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

42514:cdx4
gene id: 42514:cdx4
uniprot id: A0A3B4E817
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

42514:ctnnal1
gene id: 42514:ctnnal1
uniprot id: A0A3B4DJ69
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

42514:trpm4a
gene id: 42514:trpm4a
uniprot id: A0A3B4CNI7
names: Subcellular Location Annotation
messages: Membrane

42514:tns2b
gene id: 42514:tns2b
uniprot id: A0A3B4CAI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

42514:LOC108435120
gene id: 42514:LOC108435120
uniprot id: A0A3B4CV16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:chst11
gene id: 42514:chst11
uniprot id: A0A3B4DRH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:ccr10
gene id: 42514:ccr10
uniprot id: A0A3B4CAJ7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:psat1
gene id: 42514:psat1
uniprot id: A0A3B4C4Z9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

42514:spsb4a
gene id: 42514:spsb4a
uniprot id: A0A3B4CTI8
names: Similarity
messages: Belongs to the SPSB family.

42514:pde5ab
gene id: 42514:pde5ab
uniprot id: A0A3B4CSK5
uniprot id: A0A3B4EAM3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:lrp10
gene id: 42514:lrp10
uniprot id: A0A3B4CWU6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:armc8
gene id: 42514:armc8
uniprot id: A0A3B4D6Q7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:antxr1a
gene id: 42514:antxr1a
uniprot id: A0A3B4EAL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

42514:LOC108415675
gene id: 42514:LOC108415675
uniprot id: A0A3B4BNL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

42514:tph2
gene id: 42514:tph2
uniprot id: A0A3B4CLG9
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

42514:lhx9
gene id: 42514:lhx9
uniprot id: A0A3B4DX99
names: Subcellular Location Annotation
messages: Nucleus

42514:antxr2a
gene id: 42514:antxr2a
uniprot id: A0A3B4CQ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

42514:loxa
gene id: 42514:loxa
uniprot id: A0A3B4DKA4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

42514:acyp1
gene id: 42514:acyp1
uniprot id: A0A3B4BU87
names: Similarity
messages: Belongs to the acylphosphatase family.

42514:si:dkey-193b15.8
gene id: 42514:si:dkey-193b15.8
uniprot id: A0A3B4C7E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

42514:sbno2a
gene id: 42514:sbno2a
uniprot id: A0A3B4D9V1
names: Similarity
messages: Belongs to the SBNO family.

42514:spsb1
gene id: 42514:spsb1
uniprot id: A0A3B4CT75
names: Similarity
messages: Belongs to the SPSB family.

42514:LOC108411280
gene id: 42514:LOC108411280
uniprot id: A0A3B4ED09
names: Similarity
messages: Belongs to the fl(2)d family.

42514:si:dkey-21c1.4
gene id: 42514:si:dkey-21c1.4
uniprot id: A0A3B4EHX4
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

42514:si:ch211-161c3.6
gene id: 42514:si:ch211-161c3.6
uniprot id: A0A3B4DUS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

42514:cdr2l
gene id: 42514:cdr2l
uniprot id: A0A3B4DVN0
names: Similarity
messages: Belongs to the CDR2 family.

42514:aldh1l2
gene id: 42514:aldh1l2
uniprot id: A0A3B4DML3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

42514:tlcd5a
gene id: 42514:tlcd5a
uniprot id: A0A3B4BT98
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108441121
gene id: 42514:LOC108441121
uniprot id: A0A3B4EEX5
names: Subcellular Location Annotation
messages: cytoskeleton

42514:igfbp2b
gene id: 42514:igfbp2b
uniprot id: A0A3B4CBA6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:LOC108443058
gene id: 42514:LOC108443058
uniprot id: A0A3B4C8Q7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:LOC108424597
gene id: 42514:LOC108424597
uniprot id: A0A3B4BL65
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

42514:eif5a2
gene id: 42514:eif5a2
uniprot id: A0A3B4E6C3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

42514:prps1b
gene id: 42514:prps1b
uniprot id: A0A3B4DF22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

42514:exoc1
gene id: 42514:exoc1
uniprot id: A0A3B4BTJ7
uniprot id: A0A3B4BWL2
uniprot id: A0A3B4DJX5
uniprot id: A0A3B4DMG2
names: Similarity
messages: Belongs to the SEC3 family.

42514:dennd6aa
gene id: 42514:dennd6aa
uniprot id: A0A3B4ELC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

42514:naa30
gene id: 42514:naa30
uniprot id: A0A3B4E4H6
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

42514:dbx2
gene id: 42514:dbx2
uniprot id: A0A3B4E4H9
names: Subcellular Location Annotation
messages: Nucleus

42514:atxn1l
gene id: 42514:atxn1l
uniprot id: A0A3B4CCF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

42514:dcaf11
gene id: 42514:dcaf11
uniprot id: A0A3B4D652
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

42514:eif4e3
gene id: 42514:eif4e3
uniprot id: A0A3B4DFU1
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

42514:fam168b
gene id: 42514:fam168b
uniprot id: A0A3B4D069
names: Similarity
messages: Belongs to the FAM168 family.

42514:st3gal8
gene id: 42514:st3gal8
uniprot id: A0A3B4DID5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:dpy19l3
gene id: 42514:dpy19l3
uniprot id: A0A3B4CG07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

42514:cpn1
gene id: 42514:cpn1
uniprot id: A0A3B4DD18
names: Similarity
messages: Belongs to the peptidase M14 family.

42514:arl6ip5a
gene id: 42514:arl6ip5a
uniprot id: A0A3B4DJ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

42514:zgc:110329
gene id: 42514:zgc:110329
uniprot id: A0A3B4CY09
names: Subcellular Location Annotation
messages: Membrane

42514:entpd3
gene id: 42514:entpd3
uniprot id: A0A3B4CTY3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

42514:ip6k2a
gene id: 42514:ip6k2a
uniprot id: A0A3B4CHC4
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

42514:flvcr2b
gene id: 42514:flvcr2b
uniprot id: A0A3B4E934
uniprot id: A0A3B4ECY6
names: Subcellular Location Annotation
messages: Membrane

42514:aldh1a2
gene id: 42514:aldh1a2
uniprot id: A0A3B4CTV5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

42514:nsmce2
gene id: 42514:nsmce2
uniprot id: A0A3B4D8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

42514:rdh1
gene id: 42514:rdh1
uniprot id: A0A3B4C4C9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:prdx1
gene id: 42514:prdx1
uniprot id: A0A3B4E728
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

42514:plbd1
gene id: 42514:plbd1
uniprot id: A0A3B4D743
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

42514:mpp1
gene id: 42514:mpp1
uniprot id: A0A3B4BYZ1
names: Similarity
messages: Belongs to the MAGUK family.

42514:npepps
gene id: 42514:npepps
uniprot id: A0A3B4DVB3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

42514:map1lc3b
gene id: 42514:map1lc3b
uniprot id: A0A3B4BTC4
names: Similarity
messages: Belongs to the ATG8 family.

42514:cldn18
gene id: 42514:cldn18
uniprot id: A0A3B4BX87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:tmem161b
gene id: 42514:tmem161b
uniprot id: A0A3B4D5D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

42514:jmjd1ca
gene id: 42514:jmjd1ca
uniprot id: A0A3B4CF59
uniprot id: A0A3B4E0T2
names: Subcellular Location Annotation
messages: Nucleus

42514:cxcl12b
gene id: 42514:cxcl12b
uniprot id: A0A3B4CP07
names: Similarity
messages: Belongs to the intercrine alpha (chemokine CxC) family.

42514:dnajc18
gene id: 42514:dnajc18
uniprot id: A0A3B4DU45
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:jph2
gene id: 42514:jph2
uniprot id: A0A3B4E858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108410436
gene id: 42514:LOC108410436
uniprot id: A0A3B4D5N7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:glra2
gene id: 42514:glra2
uniprot id: A0A3B4BW53
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

42514:ifrd2
gene id: 42514:ifrd2
uniprot id: A0A3B4CJH6
uniprot id: A0A3B4E6F1
names: Similarity
messages: Belongs to the IFRD family.

42514:gadd45ba
gene id: 42514:gadd45ba
uniprot id: A0A3B4EGX0
names: Similarity
messages: Belongs to the GADD45 family.

42514:eif3ba
gene id: 42514:eif3ba
uniprot id: A0A3B4CU53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

42514:phkg1b
gene id: 42514:phkg1b
uniprot id: A0A3B4CGN1
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

42514:tspy
gene id: 42514:tspy
uniprot id: A0A3B4D1Y7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

42514:top1l
gene id: 42514:top1l
uniprot id: A0A3B4BX75
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

42514:msto1
gene id: 42514:msto1
uniprot id: A0A3B4BSB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

42514:med31
gene id: 42514:med31
uniprot id: A0A3B4C9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:ptpn18
gene id: 42514:ptpn18
uniprot id: A0A3B4CE33
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.

42514:LOC108423525
gene id: 42514:LOC108423525
uniprot id: A0A3B4BVC4
names: Similarity
messages: Belongs to the peptidase M20A family.

42514:nsmce1
gene id: 42514:nsmce1
uniprot id: A0A3B4BXL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

42514:itga1
gene id: 42514:itga1
uniprot id: A0A3B4DKV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

42514:smg5
gene id: 42514:smg5
uniprot id: A0A3B4DAA5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

42514:npc1l1
gene id: 42514:npc1l1
uniprot id: A0A3B4CNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

42514:sult1st5
gene id: 42514:sult1st5
uniprot id: A0A3B4E7Z1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:dgkaa
gene id: 42514:dgkaa
uniprot id: A0A3B4EJJ8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic diacylglycerol kinase family.
messages: Monomer.

42514:apoc1
gene id: 42514:apoc1
uniprot id: A0A3B4D990
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C1 family.
messages: Secreted

42514:LOC108434305
gene id: 42514:LOC108434305
uniprot id: A0A3B4BST3
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

42514:nck2b
gene id: 42514:nck2b
uniprot id: A0A3B4DP19
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

42514:dhx9
gene id: 42514:dhx9
uniprot id: A0A3B4ECH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

42514:pdss2
gene id: 42514:pdss2
uniprot id: A0A3B4DT08
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

42514:scamp4
gene id: 42514:scamp4
uniprot id: A0A3B4CIX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

42514:gsg1l
gene id: 42514:gsg1l
uniprot id: A0A3B4D943
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

42514:arpc5la
gene id: 42514:arpc5la
uniprot id: A0A3B4DW48
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

42514:cyfip1
gene id: 42514:cyfip1
uniprot id: A0A3B4C358
names: Similarity
messages: Belongs to the CYFIP family.

42514:ntrk2a
gene id: 42514:ntrk2a
uniprot id: A0A3B4CM08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:sap18
gene id: 42514:sap18
uniprot id: A0A3B4DRF9
names: Function
names: Similarity
messages: Belongs to the SAP18 family.
messages: Involved in the tethering of the SIN3 complex to core histone proteins.

42514:golph3
gene id: 42514:golph3
uniprot id: A0A3B4D6K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

42514:LOC108413774
gene id: 42514:LOC108413774
uniprot id: A0A3B4BWI3
names: Subcellular Location Annotation
messages: Membrane

42514:slc25a4
gene id: 42514:slc25a4
uniprot id: A0A3B4CNT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

42514:stxbp1b
gene id: 42514:stxbp1b
uniprot id: A0A3B4EC65
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

42514:hoxa10b
gene id: 42514:hoxa10b
uniprot id: A0A3B4DJ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

42514:cldnk
gene id: 42514:cldnk
uniprot id: A0A3B4CBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:atg7
gene id: 42514:atg7
uniprot id: A0A3B4DLY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress.
messages: Homodimer.
messages: Preautophagosomal structure

42514:rad51
gene id: 42514:rad51
uniprot id: A0A3B4CVE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

42514:cavin2b
gene id: 42514:cavin2b
uniprot id: A0A3B4DLX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

42514:aldh3b2
gene id: 42514:aldh3b2
uniprot id: A0A3B4CEF8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

42514:gpsm2l
gene id: 42514:gpsm2l
uniprot id: A0A3B4D5K2
uniprot id: A0A3B4EHS6
names: Similarity
messages: Belongs to the GPSM family.

42514:snx13
gene id: 42514:snx13
uniprot id: A0A3B4DST2
names: Similarity
messages: Belongs to the sorting nexin family.

42514:smim7
gene id: 42514:smim7
uniprot id: A0A3B4E3E3
names: Similarity
messages: Belongs to the SMIM7 family.

42514:ap4b1
gene id: 42514:ap4b1
uniprot id: A0A3B4CXI3
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

42514:atp6ap1lb
gene id: 42514:atp6ap1lb
uniprot id: A0A3B4CAX7
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

42514:n4bp3
gene id: 42514:n4bp3
uniprot id: A0A3B4C009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Vesicle
messages: dendrite

42514:hmces
gene id: 42514:hmces
uniprot id: A0A3B4CFR8
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

42514:rabggta
gene id: 42514:rabggta
uniprot id: A0A3B4CTL2
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

42514:grwd1
gene id: 42514:grwd1
uniprot id: A0A3B4CMI8
names: Subcellular Location Annotation
messages: Nucleus

42514:mitfa
gene id: 42514:mitfa
uniprot id: A0A3B4BS06
uniprot id: A0A3B4DJ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

42514:casr
gene id: 42514:casr
uniprot id: A0A3B4BLA2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:sgcg
gene id: 42514:sgcg
uniprot id: A0A3B4DNC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

42514:gpt2l
gene id: 42514:gpt2l
uniprot id: A0A3B4DRF2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

42514:ncbp2
gene id: 42514:ncbp2
uniprot id: A0A3B4CX01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

42514:ucp1
gene id: 42514:ucp1
uniprot id: A0A3B4E227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:ube2ka
gene id: 42514:ube2ka
uniprot id: A0A3B4D0J7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:slc17a7b
gene id: 42514:slc17a7b
uniprot id: A0A3B4BTV6
names: Subcellular Location Annotation
messages: Membrane

42514:ropn1l
gene id: 42514:ropn1l
uniprot id: A0A3B4CY69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

42514:irf8
gene id: 42514:irf8
uniprot id: A0A3B4DED6
names: Subcellular Location Annotation
messages: Nucleus

42514:tmem120a
gene id: 42514:tmem120a
uniprot id: A0A3B4CDA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

42514:arl8ba
gene id: 42514:arl8ba
uniprot id: A0A3B4DJU0
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

42514:rps9
gene id: 42514:rps9
uniprot id: A0A3B4BZ85
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

42514:wnt7bb
gene id: 42514:wnt7bb
uniprot id: A0A3B4D410
uniprot id: A0A3B4D5U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:inpp1
gene id: 42514:inpp1
uniprot id: A0A3B4DLD6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

42514:LOC108431259
gene id: 42514:LOC108431259
uniprot id: A0A3B4C9U6
names: Subcellular Location Annotation
messages: Nucleus

42514:crb2b
gene id: 42514:crb2b
uniprot id: A0A3B4BLC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:scn1ba
gene id: 42514:scn1ba
uniprot id: A0A3B4EAS9
names: Subcellular Location Annotation
messages: Membrane

42514:cacng7b
gene id: 42514:cacng7b
uniprot id: A0A3B4E5Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

42514:si:dkey-172o19.2
gene id: 42514:si:dkey-172o19.2
uniprot id: A0A3B4DE18
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

42514:cpe
gene id: 42514:cpe
uniprot id: A0A3B4C292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Membrane
messages: secretory vesicle membrane

42514:mepce
gene id: 42514:mepce
uniprot id: A0A3B4E2T1
names: Similarity
messages: Belongs to the methyltransferase superfamily.

42514:LOC108427425
gene id: 42514:LOC108427425
uniprot id: A0A3B4CGE1
names: Similarity
messages: Belongs to the Bcl-2 family.

42514:wnt4b
gene id: 42514:wnt4b
uniprot id: A0A3B4DSF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:traf5
gene id: 42514:traf5
uniprot id: A0A3B4C246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

42514:LOC108419124
gene id: 42514:LOC108419124
uniprot id: A0A3B4CU81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108436673
gene id: 42514:LOC108436673
uniprot id: A0A3B4D8T8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:LOC108413821
gene id: 42514:LOC108413821
uniprot id: A0A3B4DD16
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

42514:cldn7a
gene id: 42514:cldn7a
uniprot id: A0A3B4DWJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:laptm4a
gene id: 42514:laptm4a
uniprot id: A0A3B4DTR3
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

42514:rpl11
gene id: 42514:rpl11
uniprot id: A0A3B4EH11
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

42514:galnt10
gene id: 42514:galnt10
uniprot id: A0A3B4CWD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:dph5
gene id: 42514:dph5
uniprot id: A0A3B4D0G5
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

42514:rcan1b
gene id: 42514:rcan1b
uniprot id: A0A3B4DNE4
uniprot id: A0A3B4DPX9
names: Similarity
messages: Belongs to the RCAN family.

42514:lin7c
gene id: 42514:lin7c
uniprot id: A0A3B4CR07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

42514:cryba2a
gene id: 42514:cryba2a
uniprot id: A0A3B4EAA4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:LOC108440014
gene id: 42514:LOC108440014
uniprot id: A0A3B4D1E4
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:acvr1bb
gene id: 42514:acvr1bb
uniprot id: A0A3B4BWP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:myca
gene id: 42514:myca
uniprot id: A0A3B4BY67
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

42514:cnot10
gene id: 42514:cnot10
uniprot id: A0A3B4CXK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

42514:heatr1
gene id: 42514:heatr1
uniprot id: A0A3B4EG87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEATR1/UTP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

42514:sigirr
gene id: 42514:sigirr
uniprot id: A0A3B4BQL7
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

42514:osbpl2a
gene id: 42514:osbpl2a
uniprot id: A0A3B4CUI0
names: Similarity
messages: Belongs to the OSBP family.

42514:setdb1b
gene id: 42514:setdb1b
uniprot id: A0A3B4CXR0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

42514:LOC108439349
gene id: 42514:LOC108439349
uniprot id: A0A3B4D9G8
names: Similarity
messages: Belongs to the peptidase M14 family.

42514:gpr1
gene id: 42514:gpr1
uniprot id: A0A3B4EDU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

42514:id4
gene id: 42514:id4
uniprot id: A0A3B4CTM8
names: Subcellular Location Annotation
messages: Nucleus

42514:slc20a1a
gene id: 42514:slc20a1a
uniprot id: A0A3B4C1P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

42514:fabp2
gene id: 42514:fabp2
uniprot id: A0A3B4DL21
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:adgrl4
gene id: 42514:adgrl4
uniprot id: A0A3B4CFJ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108443715
gene id: 42514:LOC108443715
uniprot id: A0A3B4BUW1
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:osbpl3b
gene id: 42514:osbpl3b
uniprot id: A0A3B4BRV3
names: Similarity
messages: Belongs to the OSBP family.

42514:sh3glb1b
gene id: 42514:sh3glb1b
uniprot id: A0A3B4DXX9
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Mitochondrion outer membrane

42514:igf1ra
gene id: 42514:igf1ra
uniprot id: A0A3B4C8M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

42514:rrp8
gene id: 42514:rrp8
uniprot id: A0A3B4EGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Probable methyltransferase required to silence rDNA.
messages: nucleolus

42514:tlcd1
gene id: 42514:tlcd1
uniprot id: A0A3B4CBT2
names: Subcellular Location Annotation
messages: Membrane

42514:kif21a
gene id: 42514:kif21a
uniprot id: A0A3B4DHI6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:LOC108443236
gene id: 42514:LOC108443236
uniprot id: A0A3B4BN81
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

42514:opn4a
gene id: 42514:opn4a
uniprot id: A0A3B4BR80
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:hao1
gene id: 42514:hao1
uniprot id: A0A3B4ERN9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

42514:ccn2a
gene id: 42514:ccn2a
uniprot id: A0A3B4CA12
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:pus7
gene id: 42514:pus7
uniprot id: A0A3B4DQ60
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

42514:dcbld1
gene id: 42514:dcbld1
uniprot id: A0A3B4CCY2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tspan2a
gene id: 42514:tspan2a
uniprot id: A0A3B4DMU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:igfbp1b
gene id: 42514:igfbp1b
uniprot id: A0A3B4BUF9
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:polr3f
gene id: 42514:polr3f
uniprot id: A0A3B4EL50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

42514:cnot7
gene id: 42514:cnot7
uniprot id: A0A3B4EAG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

42514:slc25a1b
gene id: 42514:slc25a1b
uniprot id: A0A3B4C6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:LOC108440592
gene id: 42514:LOC108440592
uniprot id: A0A3B4EC55
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

42514:adamts15a
gene id: 42514:adamts15a
uniprot id: A0A3B4C565
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:dldh
gene id: 42514:dldh
uniprot id: A0A3B4CI39
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

42514:uncx
gene id: 42514:uncx
uniprot id: A0A3B4BYH7
names: Subcellular Location Annotation
messages: Nucleus

42514:fam221a
gene id: 42514:fam221a
uniprot id: A0A3B4BR67
names: Similarity
messages: Belongs to the FAM221 family.

42514:prkaa2
gene id: 42514:prkaa2
uniprot id: A0A3B4DG22
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

42514:c8h11orf49
gene id: 42514:c8h11orf49
uniprot id: A0A3B4C1A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: cytoskeleton

42514:LOC108429683
gene id: 42514:LOC108429683
uniprot id: A0A3B4CDJ3
names: Subcellular Location Annotation
messages: Cytoplasm

42514:fam32a
gene id: 42514:fam32a
uniprot id: A0A3B4BJU7
names: Similarity
messages: Belongs to the FAM32 family.

42514:ndc1
gene id: 42514:ndc1
uniprot id: A0A3B4C2H7
uniprot id: A0A3B4C3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

42514:tefa
gene id: 42514:tefa
uniprot id: A0A3B4C2X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

42514:rnd3a
gene id: 42514:rnd3a
uniprot id: A0A3B4C9Z6
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

42514:pop4
gene id: 42514:pop4
uniprot id: A0A3B4EHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

42514:man1a1
gene id: 42514:man1a1
uniprot id: A0A3B4CD16
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

42514:si:ch73-352p4.8
gene id: 42514:si:ch73-352p4.8
uniprot id: A0A3B4EFS2
names: Subcellular Location Annotation
messages: Membrane

42514:exoc3l2a
gene id: 42514:exoc3l2a
uniprot id: A0A3B4D2L1
names: Similarity
messages: Belongs to the SEC6 family.

42514:zgc:103681
gene id: 42514:zgc:103681
uniprot id: A0A3B4DLZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

42514:atm
gene id: 42514:atm
uniprot id: A0A3B4C7R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus

42514:ppp3r1a
gene id: 42514:ppp3r1a
uniprot id: A0A3B4E629
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

42514:LOC108427622
gene id: 42514:LOC108427622
uniprot id: A0A3B4EPI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:zgc:77849
gene id: 42514:zgc:77849
uniprot id: A0A3B4DWU8
names: Subcellular Location Annotation
messages: Nucleus

42514:ramp1
gene id: 42514:ramp1
uniprot id: A0A3B4D8U7
names: Similarity
messages: Belongs to the RAMP family.

42514:lamb2
gene id: 42514:lamb2
uniprot id: A0A3B4EHA4
uniprot id: A0A3B4EIU5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

42514:hmga1b
gene id: 42514:hmga1b
uniprot id: A0A3B4C4H9
names: Similarity
messages: Belongs to the HMGA family.

42514:LOC108444315
gene id: 42514:LOC108444315
uniprot id: A0A3B4C0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

42514:cdk11b
gene id: 42514:cdk11b
uniprot id: A0A3B4E7I3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

42514:gdi2
gene id: 42514:gdi2
uniprot id: A0A3B4DG14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

42514:cacng3b
gene id: 42514:cacng3b
uniprot id: A0A3B4CAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

42514:LOC108413812
gene id: 42514:LOC108413812
uniprot id: A0A3B4EK85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:praf2
gene id: 42514:praf2
uniprot id: A0A3B4DL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

42514:vdac3
gene id: 42514:vdac3
uniprot id: A0A3B4BL05
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

42514:vangl1
gene id: 42514:vangl1
uniprot id: A0A3B4BNI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

42514:slc17a5
gene id: 42514:slc17a5
uniprot id: A0A3B4DN62
names: Subcellular Location Annotation
messages: Membrane

42514:traf6
gene id: 42514:traf6
uniprot id: A0A3B4CH23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

42514:kif21b
gene id: 42514:kif21b
uniprot id: A0A3B4C1A2
uniprot id: A0A3B4C1Q2
uniprot id: A0A3B4DUC0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:b4galt7
gene id: 42514:b4galt7
uniprot id: A0A3B4D4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

42514:dpf2l
gene id: 42514:dpf2l
uniprot id: A0A3B4D2H5
names: Similarity
messages: Belongs to the requiem/DPF family.

42514:LOC108422693
gene id: 42514:LOC108422693
uniprot id: A0A3B4DVV8
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

42514:gnal
gene id: 42514:gnal
uniprot id: A0A3B4EHC4
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

42514:im:7154036
gene id: 42514:im:7154036
uniprot id: A0A3B4CYP1
names: Similarity
messages: Belongs to the kindlin family.

42514:pygma
gene id: 42514:pygma
uniprot id: A0A3B4C8R2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

42514:hoxa11a
gene id: 42514:hoxa11a
uniprot id: A0A3B4BRQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:erh
gene id: 42514:erh
uniprot id: A0A3B4CJD2
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

42514:slc24a6a
gene id: 42514:slc24a6a
uniprot id: A0A3B4E7N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

42514:LOC108425545
gene id: 42514:LOC108425545
uniprot id: A0A3B4CU69
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

42514:mkxb
gene id: 42514:mkxb
uniprot id: A0A3B4C7J1
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108442647
gene id: 42514:LOC108442647
uniprot id: A0A3B4DJ84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
messages: Cytoplasm

42514:slc25a44b
gene id: 42514:slc25a44b
uniprot id: A0A3B4CKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:mrm1
gene id: 42514:mrm1
uniprot id: A0A3B4DZ94
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

42514:tnfsf10l
gene id: 42514:tnfsf10l
uniprot id: A0A3B4D7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

42514:LOC108440270
gene id: 42514:LOC108440270
uniprot id: A0A3B4C4X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

42514:npm1a
gene id: 42514:npm1a
uniprot id: A0A3B4D9D3
names: Similarity
messages: Belongs to the nucleoplasmin family.

42514:cpt1a2b
gene id: 42514:cpt1a2b
uniprot id: A0A3B4E6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:LOC108440368
gene id: 42514:LOC108440368
uniprot id: A0A3B4DIF4
names: Subcellular Location Annotation
messages: Membrane

42514:hs6st1b
gene id: 42514:hs6st1b
uniprot id: A0A3B4DGJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

42514:trappc2l
gene id: 42514:trappc2l
uniprot id: A0A3B4CU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

42514:tfap2c
gene id: 42514:tfap2c
uniprot id: A0A3B4CG63
names: Similarity
messages: Belongs to the AP-2 family.

42514:zyg11
gene id: 42514:zyg11
uniprot id: A0A3B4DJJ1
names: Similarity
messages: Belongs to the zyg-11 family.

42514:tpte
gene id: 42514:tpte
uniprot id: A0A3B4D859
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

42514:yaf2
gene id: 42514:yaf2
uniprot id: A0A3B4D027
names: Subcellular Location Annotation
messages: Nucleus

42514:arg2
gene id: 42514:arg2
uniprot id: A0A3B4DX88
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

42514:ppm1bb
gene id: 42514:ppm1bb
uniprot id: A0A3B4DKJ4
uniprot id: A0A3B4DP66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

42514:si:dkey-191g9.7
gene id: 42514:si:dkey-191g9.7
uniprot id: A0A3B4DGV3
names: Function
messages: May be involved in neurite outgrowth.

42514:eml2
gene id: 42514:eml2
uniprot id: A0A3B4BTB5
uniprot id: A0A3B4DJR0
names: Similarity
messages: Belongs to the WD repeat EMAP family.

42514:pofut1
gene id: 42514:pofut1
uniprot id: A0A3B4DNF2
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

42514:LOC108438913
gene id: 42514:LOC108438913
uniprot id: A0A3B4D2U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

42514:prkacbb
gene id: 42514:prkacbb
uniprot id: A0A3B4CA69
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

42514:rnasekb
gene id: 42514:rnasekb
uniprot id: A0A3B4BWB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

42514:ppardb
gene id: 42514:ppardb
uniprot id: A0A3B4E5E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:ddx43
gene id: 42514:ddx43
uniprot id: A0A3B4DN84
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:u2af2a
gene id: 42514:u2af2a
uniprot id: A0A3B4CIT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

42514:LOC108444406
gene id: 42514:LOC108444406
uniprot id: A0A3B4DMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

42514:smad9
gene id: 42514:smad9
uniprot id: A0A3B4CQX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:mns1
gene id: 42514:mns1
uniprot id: A0A3B4CD38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

42514:prkacba
gene id: 42514:prkacba
uniprot id: A0A3B4CG40
uniprot id: A0A3B4DYY1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

42514:cd40lg
gene id: 42514:cd40lg
uniprot id: A0A3B4E616
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:wls
gene id: 42514:wls
uniprot id: A0A3B4DC23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

42514:spns1
gene id: 42514:spns1
uniprot id: A0A3B4CEU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

42514:soga1
gene id: 42514:soga1
uniprot id: A0A3B4BY82
names: Similarity
messages: Belongs to the SOGA family.

42514:ugcg
gene id: 42514:ugcg
uniprot id: A0A3B4CG67
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

42514:mesd
gene id: 42514:mesd
uniprot id: A0A3B4C2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

42514:yipf5
gene id: 42514:yipf5
uniprot id: A0A3B4D753
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

42514:ppib
gene id: 42514:ppib
uniprot id: A0A3B4DBR6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

42514:tmem192
gene id: 42514:tmem192
uniprot id: A0A3B4DIA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

42514:ergic3
gene id: 42514:ergic3
uniprot id: A0A3B4DQ25
uniprot id: A0A3B4DSL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

42514:mpdu1b
gene id: 42514:mpdu1b
uniprot id: A0A3B4DAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane

42514:mul1b
gene id: 42514:mul1b
uniprot id: A0A3B4CVU7
names: Subcellular Location Annotation
messages: Membrane

42514:kpna1
gene id: 42514:kpna1
uniprot id: A0A3B4E767
names: Similarity
messages: Belongs to the importin alpha family.

42514:rps25
gene id: 42514:rps25
uniprot id: A0A3B4EM59
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

42514:pam
gene id: 42514:pam
uniprot id: A0A3B4CRU0
names: Cofactor
names: Similarity
messages: Binds 2 Cu(2+) ions per subunit.
messages: Binds one Zn(2+) ion per subunit.
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.

42514:slc40a1
gene id: 42514:slc40a1
uniprot id: A0A3B4CWC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

42514:LOC108425951
gene id: 42514:LOC108425951
uniprot id: A0A3B4EQ29
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

42514:zgc:55558
gene id: 42514:zgc:55558
uniprot id: A0A3B4DUQ9
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:si:dkey-197c15.6
gene id: 42514:si:dkey-197c15.6
uniprot id: A0A3B4D8A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

42514:hoxc12b
gene id: 42514:hoxc12b
uniprot id: A0A3B4DJR9
names: Subcellular Location Annotation
messages: Nucleus

42514:kita
gene id: 42514:kita
uniprot id: A0A3B4DN21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:fam120b
gene id: 42514:fam120b
uniprot id: A0A3B4DTL0
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

42514:nutf2
gene id: 42514:nutf2
uniprot id: A0A3B4CL27
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

42514:ednrbb
gene id: 42514:ednrbb
uniprot id: A0A3B4D7Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:LOC108431540
gene id: 42514:LOC108431540
uniprot id: A0A3B4DLL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

42514:snrpc
gene id: 42514:snrpc
uniprot id: A0A3B4DW81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

42514:gfra4a
gene id: 42514:gfra4a
uniprot id: A0A3B4E4U2
names: Similarity
messages: Belongs to the GDNFR family.

42514:zgc:153733
gene id: 42514:zgc:153733
uniprot id: A0A3B4C9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

42514:ptges
gene id: 42514:ptges
uniprot id: A0A3B4DCD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

42514:camk2n1a
gene id: 42514:camk2n1a
uniprot id: A0A3B4CVM5
names: Similarity
messages: Belongs to the CAMK2N family.

42514:yy1a
gene id: 42514:yy1a
uniprot id: A0A3B4E5W7
names: Similarity
messages: Belongs to the YY transcription factor family.

42514:ap1m2
gene id: 42514:ap1m2
uniprot id: A0A3B4DHQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

42514:si:ch211-225b10.3
gene id: 42514:si:ch211-225b10.3
uniprot id: A0A3B4DFM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

42514:LOC108432167
gene id: 42514:LOC108432167
uniprot id: A0A3B4D815
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:rps2
gene id: 42514:rps2
uniprot id: A0A3B4EKH1
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

42514:bpgm
gene id: 42514:bpgm
uniprot id: A0A3B4CUY1
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

42514:niban1b
gene id: 42514:niban1b
uniprot id: A0A3B4DCQ0
names: Similarity
messages: Belongs to the Niban family.

42514:pcmtd2a
gene id: 42514:pcmtd2a
uniprot id: A0A3B4CUY0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

42514:dut
gene id: 42514:dut
uniprot id: A0A3B4EJA2
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

42514:gga3a
gene id: 42514:gga3a
uniprot id: A0A3B4C8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

42514:szrd1
gene id: 42514:szrd1
uniprot id: A0A3B4CS10
names: Similarity
messages: Belongs to the SZRD1 family.

42514:kdsr
gene id: 42514:kdsr
uniprot id: A0A3B4CH54
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:mxe
gene id: 42514:mxe
uniprot id: A0A3B4CEH9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

42514:LOC108431583
gene id: 42514:LOC108431583
uniprot id: A0A3B4DE78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

42514:vegfba
gene id: 42514:vegfba
uniprot id: A0A3B4EL83
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

42514:LOC108442945
gene id: 42514:LOC108442945
uniprot id: A0A3B4E3H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

42514:LOC108413929
gene id: 42514:LOC108413929
uniprot id: A0A3B4CWZ3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:marveld2b
gene id: 42514:marveld2b
uniprot id: A0A3B4EGQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:c25h16orf87
gene id: 42514:c25h16orf87
uniprot id: A0A3B4CCU5
names: Similarity
messages: Belongs to the UPF0547 family.

42514:ndufs8b
gene id: 42514:ndufs8b
uniprot id: A0A3B4D7N3
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

42514:LOC108438075
gene id: 42514:LOC108438075
uniprot id: A0A3B4DRM2
names: Subcellular Location Annotation
messages: Membrane

42514:slc15a1a
gene id: 42514:slc15a1a
uniprot id: A0A3B4EE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

42514:nptx2b
gene id: 42514:nptx2b
uniprot id: A0A3B4BYH1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ssr3
gene id: 42514:ssr3
uniprot id: A0A3B4CD80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

42514:LOC108433551
gene id: 42514:LOC108433551
uniprot id: A0A3B4CI97
names: Similarity
names: Subcellular Location Annotation
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

42514:nit2
gene id: 42514:nit2
uniprot id: A0A3B4DQV6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

42514:LOC108443717
gene id: 42514:LOC108443717
uniprot id: A0A3B4BUX1
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:LOC108433477
gene id: 42514:LOC108433477
uniprot id: A0A3B4E797
names: Caution
names: Similarity
messages: Belongs to the Ntn-hydrolase family.
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:hs6st1a
gene id: 42514:hs6st1a
uniprot id: A0A3B4EHH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

42514:zgc:154075
gene id: 42514:zgc:154075
uniprot id: A0A3B4CNU8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

42514:slc41a2b
gene id: 42514:slc41a2b
uniprot id: A0A3B4C0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

42514:atxn1a
gene id: 42514:atxn1a
uniprot id: A0A3B4C018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

42514:arrb1
gene id: 42514:arrb1
uniprot id: A0A3B4DL71
names: Similarity
messages: Belongs to the arrestin family.

42514:rftn2
gene id: 42514:rftn2
uniprot id: A0A3B4DH11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

42514:cpsf4
gene id: 42514:cpsf4
uniprot id: A0A3B4EF74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

42514:gna14a
gene id: 42514:gna14a
uniprot id: A0A3B4E5Y0
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

42514:slc13a5a
gene id: 42514:slc13a5a
uniprot id: A0A3B4CCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

42514:epn1
gene id: 42514:epn1
uniprot id: A0A3B4CKC2
uniprot id: A0A3B4CKC9
names: Similarity
messages: Belongs to the epsin family.

42514:LOC108434146
gene id: 42514:LOC108434146
uniprot id: A0A3B4DVX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:nrtn
gene id: 42514:nrtn
uniprot id: A0A3B4D1V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

42514:ppil4
gene id: 42514:ppil4
uniprot id: A0A3B4C6T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

42514:bora
gene id: 42514:bora
uniprot id: A0A3B4BZJ4
names: Similarity
messages: Belongs to the BORA family.

42514:LOC108433253
gene id: 42514:LOC108433253
uniprot id: A0A3B4ELR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108426311
gene id: 42514:LOC108426311
uniprot id: A0A3B4C274
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

42514:chmp4ba
gene id: 42514:chmp4ba
uniprot id: A0A3B4DU08
names: Similarity
messages: Belongs to the SNF7 family.

42514:dact1
gene id: 42514:dact1
uniprot id: A0A3B4DJT2
names: Similarity
messages: Belongs to the dapper family.

42514:pcolce2b
gene id: 42514:pcolce2b
uniprot id: A0A3B4DHY8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:apoeb
gene id: 42514:apoeb
uniprot id: A0A3B4D5D4
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

42514:taf7
gene id: 42514:taf7
uniprot id: A0A3B4E7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

42514:foxn2b
gene id: 42514:foxn2b
uniprot id: A0A3B4BWK9
names: Subcellular Location Annotation
messages: Nucleus

42514:kiaa1191
gene id: 42514:kiaa1191
uniprot id: A0A3B4DG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

42514:ahdc1
gene id: 42514:ahdc1
uniprot id: A0A3B4EHK0
names: Subcellular Location Annotation
messages: Nucleus

42514:prkab1a
gene id: 42514:prkab1a
uniprot id: A0A3B4D285
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

42514:LOC108439433
gene id: 42514:LOC108439433
uniprot id: A0A3B4ECU0
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

42514:cops9
gene id: 42514:cops9
uniprot id: A0A3B4DLX6
names: Similarity
messages: Belongs to the CSN9 family.

42514:LOC108433876
gene id: 42514:LOC108433876
uniprot id: A0A3B4DE48
names: Similarity
messages: Belongs to the MS4A family.

42514:desi1a
gene id: 42514:desi1a
uniprot id: A0A3B4E8F6
names: Similarity
messages: Belongs to the DeSI family.

42514:rpl10a
gene id: 42514:rpl10a
uniprot id: A0A3B4CLH3
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

42514:si:ch211-225b11.4
gene id: 42514:si:ch211-225b11.4
uniprot id: A0A3B4C2Q5
names: Function
names: Similarity
messages: Belongs to the THADA family.
messages: Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.

42514:LOC108437208
gene id: 42514:LOC108437208
uniprot id: A0A3B4DBS0
names: Subcellular Location Annotation
messages: ruffle membrane

42514:LOC108440375
gene id: 42514:LOC108440375
uniprot id: A0A3B4BUA5
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108415106
gene id: 42514:LOC108415106
uniprot id: A0A3B4EH29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

42514:LOC108412782
gene id: 42514:LOC108412782
uniprot id: A0A3B4EC28
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

42514:etf1b
gene id: 42514:etf1b
uniprot id: A0A3B4CXK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

42514:smpd2b
gene id: 42514:smpd2b
uniprot id: A0A3B4BRS7
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

42514:letm2
gene id: 42514:letm2
uniprot id: A0A3B4CMX5
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

42514:rnf152
gene id: 42514:rnf152
uniprot id: A0A3B4CY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

42514:fam98a
gene id: 42514:fam98a
uniprot id: A0A3B4BYH8
names: Similarity
messages: Belongs to the FAM98 family.

42514:gmpr2
gene id: 42514:gmpr2
uniprot id: A0A3B4EC32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

42514:zfpl1
gene id: 42514:zfpl1
uniprot id: A0A3B4D0S6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZFPL1 family.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

42514:nde1
gene id: 42514:nde1
uniprot id: A0A3B4DTH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

42514:LOC108423711
gene id: 42514:LOC108423711
uniprot id: A0A3B4EDN9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

42514:abcb10
gene id: 42514:abcb10
uniprot id: A0A3B4CB15
names: Subcellular Location Annotation
messages: Membrane

42514:pycr1b
gene id: 42514:pycr1b
uniprot id: A0A3B4BLG5
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

42514:arl8bb
gene id: 42514:arl8bb
uniprot id: A0A3B4CI82
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

42514:slc26a10
gene id: 42514:slc26a10
uniprot id: A0A3B4CZS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

42514:agxt2
gene id: 42514:agxt2
uniprot id: A0A3B4ECH3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

42514:LOC108436281
gene id: 42514:LOC108436281
uniprot id: A0A3B4E187
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: dendrite
messages: sarcolemma
messages: synaptosome

42514:LOC108433092
gene id: 42514:LOC108433092
uniprot id: A0A3B4DQW6
names: Similarity
messages: Belongs to the HARBI1 family.

42514:sdr16c5b
gene id: 42514:sdr16c5b
uniprot id: A0A3B4CWQ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:cep19
gene id: 42514:cep19
uniprot id: A0A3B4EAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

42514:saraf
gene id: 42514:saraf
uniprot id: A0A3B4CDB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:gem
gene id: 42514:gem
uniprot id: A0A3B4DIQ3
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

42514:LOC108437608
gene id: 42514:LOC108437608
uniprot id: A0A3B4C1V7
names: Subcellular Location Annotation
messages: Membrane

42514:gbe1a
gene id: 42514:gbe1a
uniprot id: A0A3B4EFK2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

42514:mapre2
gene id: 42514:mapre2
uniprot id: A0A3B4C4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

42514:tomt
gene id: 42514:tomt
uniprot id: A0A3B4BNY1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

42514:itpk1b
gene id: 42514:itpk1b
uniprot id: A0A3B4E5I4
names: Similarity
messages: Belongs to the ITPK1 family.

42514:pfdn6
gene id: 42514:pfdn6
uniprot id: A0A3B4CT91
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

42514:apoda.1
gene id: 42514:apoda.1
uniprot id: A0A3B4C0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

42514:dnase1l1
gene id: 42514:dnase1l1
uniprot id: A0A3B4DZ16
names: Similarity
messages: Belongs to the DNase I family.

42514:alg9
gene id: 42514:alg9
uniprot id: A0A3B4CBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:alad
gene id: 42514:alad
uniprot id: A0A3B4D8D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

42514:trmt2b
gene id: 42514:trmt2b
uniprot id: A0A3B4BRV5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:cnn1b
gene id: 42514:cnn1b
uniprot id: A0A3B4BQC6
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

42514:LOC108414863
gene id: 42514:LOC108414863
uniprot id: A0A3B4DC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: Vacuole membrane

42514:si:dkey-79d12.5
gene id: 42514:si:dkey-79d12.5
uniprot id: A0A3B4EJN4
names: Similarity
messages: Belongs to the BTG family.

42514:tubgcp5
gene id: 42514:tubgcp5
uniprot id: A0A3B4DRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

42514:bco2a
gene id: 42514:bco2a
uniprot id: A0A3B4DTC2
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

42514:snrpg
gene id: 42514:snrpg
uniprot id: A0A3B4CY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

42514:LOC108431212
gene id: 42514:LOC108431212
uniprot id: A0A3B4CKU1
names: Similarity
messages: Belongs to the arrestin family.

42514:zdhhc20b
gene id: 42514:zdhhc20b
uniprot id: A0A3B4EDG3
uniprot id: A0A3B4EF70
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:nadsyn1
gene id: 42514:nadsyn1
uniprot id: A0A3B4EDT0
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

42514:zgc:154046
gene id: 42514:zgc:154046
uniprot id: A0A3B4CK71
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

42514:tmtopsb
gene id: 42514:tmtopsb
uniprot id: A0A3B4DM11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:b3gnt2l
gene id: 42514:b3gnt2l
uniprot id: A0A3B4DAD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:skib
gene id: 42514:skib
uniprot id: A0A3B4BKG1
names: Similarity
messages: Belongs to the SKI family.

42514:map4k3b
gene id: 42514:map4k3b
uniprot id: A0A3B4CY84
uniprot id: A0A3B4D0K3
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

42514:phf2
gene id: 42514:phf2
uniprot id: A0A3B4DIF0
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

42514:ints8
gene id: 42514:ints8
uniprot id: A0A3B4EN15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

42514:LOC108428599
gene id: 42514:LOC108428599
uniprot id: A0A3B4BQ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:LOC108436755
gene id: 42514:LOC108436755
uniprot id: A0A3B4CX76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

42514:si:ch211-191a24.4
gene id: 42514:si:ch211-191a24.4
uniprot id: A0A3B4DAX9
names: Subcellular Location Annotation
messages: Membrane

42514:pdp1
gene id: 42514:pdp1
uniprot id: A0A3B4BPF4
names: Similarity
messages: Belongs to the PP2C family.

42514:ano7
gene id: 42514:ano7
uniprot id: A0A3B4C307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

42514:tprkb
gene id: 42514:tprkb
uniprot id: A0A3B4EP71
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

42514:grpel1
gene id: 42514:grpel1
uniprot id: A0A3B4CEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

42514:setd3
gene id: 42514:setd3
uniprot id: A0A3B4EAC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm

42514:tecpr1a
gene id: 42514:tecpr1a
uniprot id: A0A3B4BUR6
names: Similarity
messages: Belongs to the TECPR1 family.

42514:pigs
gene id: 42514:pigs
uniprot id: A0A3B4CAQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:rps20
gene id: 42514:rps20
uniprot id: A0A3B4EAE5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

42514:myo6b
gene id: 42514:myo6b
uniprot id: A0A3B4CI31
uniprot id: A0A3B4E0J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus
messages: ruffle membrane
messages: trans-Golgi network membrane

42514:peli1b
gene id: 42514:peli1b
uniprot id: A0A3B4EKL5
names: Similarity
messages: Belongs to the pellino family.

42514:hrasb
gene id: 42514:hrasb
uniprot id: A0A3B4BNM3
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:ptgs2a
gene id: 42514:ptgs2a
uniprot id: A0A3B4CMQ4
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108418701
gene id: 42514:LOC108418701
uniprot id: A0A3B4CY83
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:ezh1
gene id: 42514:ezh1
uniprot id: A0A3B4CHW0
names: Subcellular Location Annotation
messages: Nucleus

42514:dhx29
gene id: 42514:dhx29
uniprot id: A0A3B4DL91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC).

42514:gnb5b
gene id: 42514:gnb5b
uniprot id: A0A3B4D1P7
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

42514:LOC108415267
gene id: 42514:LOC108415267
uniprot id: A0A3B4DHQ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:syk
gene id: 42514:syk
uniprot id: A0A3B4CS48
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

42514:LOC108415213
gene id: 42514:LOC108415213
uniprot id: A0A3B4CX07
names: Similarity
messages: Belongs to the MHC class I family.

42514:ccnd2a
gene id: 42514:ccnd2a
uniprot id: A0A3B4BKX1
names: Similarity
messages: Belongs to the cyclin family.

42514:micos13
gene id: 42514:micos13
uniprot id: A0A3B4DR31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

42514:pkn1a
gene id: 42514:pkn1a
uniprot id: A0A3B4D0N3
uniprot id: A0A3B4D2M6
uniprot id: A0A3B4D2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

42514:pdxkb
gene id: 42514:pdxkb
uniprot id: A0A3B4D3P7
uniprot id: A0A3B4EJS3
names: Similarity
messages: Belongs to the pyridoxine kinase family.

42514:eif3g
gene id: 42514:eif3g
uniprot id: A0A3B4CJ78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

42514:ethe1
gene id: 42514:ethe1
uniprot id: A0A3B4EPI2
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

42514:rps19bp1
gene id: 42514:rps19bp1
uniprot id: A0A3B4BNS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

42514:foxk2
gene id: 42514:foxk2
uniprot id: A0A3B4EK33
names: Subcellular Location Annotation
messages: Nucleus

42514:cldn15lb
gene id: 42514:cldn15lb
uniprot id: A0A3B4E0I0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:sgta
gene id: 42514:sgta
uniprot id: A0A3B4EHG4
names: Similarity
messages: Belongs to the SGT family.

42514:LOC108442979
gene id: 42514:LOC108442979
uniprot id: A0A3B4CCN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

42514:LOC108430243
gene id: 42514:LOC108430243
uniprot id: A0A3B4BZV2
uniprot id: A0A3B4DPP3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:LOC108432418
gene id: 42514:LOC108432418
uniprot id: A0A3B4DTZ2
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108427208
gene id: 42514:LOC108427208
uniprot id: A0A3B4D0E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:nxph1
gene id: 42514:nxph1
uniprot id: A0A3B4C6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

42514:uba2
gene id: 42514:uba2
uniprot id: A0A3B4C2J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

42514:lacc1
gene id: 42514:lacc1
uniprot id: A0A3B4E587
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

42514:ebf1b
gene id: 42514:ebf1b
uniprot id: A0A3B4C8T1
uniprot id: A0A3B4DTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

42514:ppp4cb
gene id: 42514:ppp4cb
uniprot id: A0A3B4EFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

42514:snx30
gene id: 42514:snx30
uniprot id: A0A3B4E080
names: Similarity
messages: Belongs to the sorting nexin family.

42514:dtd1
gene id: 42514:dtd1
uniprot id: A0A3B4C3B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

42514:vps51
gene id: 42514:vps51
uniprot id: A0A3B4ENY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Endosome
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

42514:glcea
gene id: 42514:glcea
uniprot id: A0A3B4DIV6
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

42514:e2f5
gene id: 42514:e2f5
uniprot id: A0A3B4D7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

42514:igbp1
gene id: 42514:igbp1
uniprot id: A0A3B4EH07
names: Similarity
messages: Belongs to the IGBP1/TAP42 family.

42514:LOC108435109
gene id: 42514:LOC108435109
uniprot id: A0A3B4CTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:march4l
gene id: 42514:march4l
uniprot id: A0A3B4C1X1
names: Subcellular Location Annotation
messages: Membrane

42514:kcns3a
gene id: 42514:kcns3a
uniprot id: A0A3B4BYI0
names: Subcellular Location Annotation
messages: Membrane

42514:c6h2orf49
gene id: 42514:c6h2orf49
uniprot id: A0A3B4BWY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

42514:eya1
gene id: 42514:eya1
uniprot id: A0A3B4D3K3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

42514:dhh
gene id: 42514:dhh
uniprot id: A0A3B4D4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

42514:lmx1ba
gene id: 42514:lmx1ba
uniprot id: A0A3B4CY34
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108414621
gene id: 42514:LOC108414621
uniprot id: A0A3B4CV30
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

42514:mospd1
gene id: 42514:mospd1
uniprot id: A0A3B4E979
names: Subcellular Location Annotation
messages: Membrane

42514:snx33
gene id: 42514:snx33
uniprot id: A0A3B4BQ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

42514:actr10
gene id: 42514:actr10
uniprot id: A0A3B4CS12
names: Similarity
messages: Belongs to the actin family.

42514:si:rp71-1d10.5
gene id: 42514:si:rp71-1d10.5
uniprot id: A0A3B4EHS3
names: Subcellular Location Annotation
messages: Membrane

42514:lhx1a
gene id: 42514:lhx1a
uniprot id: A0A3B4BVI9
names: Subcellular Location Annotation
messages: Nucleus

42514:hoxb5a
gene id: 42514:hoxb5a
uniprot id: A0A3B4E136
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:cited4b
gene id: 42514:cited4b
uniprot id: A0A3B4CBS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

42514:LOC108438993
gene id: 42514:LOC108438993
uniprot id: A0A3B4CMS7
names: Subcellular Location Annotation
messages: Membrane

42514:nf2a
gene id: 42514:nf2a
uniprot id: A0A3B4D2T5
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

42514:sephs1
gene id: 42514:sephs1
uniprot id: A0A3B4D1Q4
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

42514:zgc:163143
gene id: 42514:zgc:163143
uniprot id: A0A3B4EK40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

42514:gpsm1b
gene id: 42514:gpsm1b
uniprot id: A0A3B4BLH0
uniprot id: A0A3B4BPL0
names: Similarity
messages: Belongs to the GPSM family.

42514:LOC108435793
gene id: 42514:LOC108435793
uniprot id: A0A3B4CFZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dipk2aa
gene id: 42514:dipk2aa
uniprot id: A0A3B4E2G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

42514:rffl
gene id: 42514:rffl
uniprot id: A0A3B4C359
names: Subcellular Location Annotation
messages: Cell membrane

42514:elf1
gene id: 42514:elf1
uniprot id: A0A3B4CPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:gc
gene id: 42514:gc
uniprot id: A0A3B4DZM4
names: Function
names: Subcellular Location Annotation
messages: Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
messages: Secreted

42514:nfil3-6
gene id: 42514:nfil3-6
uniprot id: A0A3B4DHN8
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

42514:gtf2h5
gene id: 42514:gtf2h5
uniprot id: A0A3B4C8C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

42514:LOC108444462
gene id: 42514:LOC108444462
uniprot id: A0A3B4BSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

42514:pth2
gene id: 42514:pth2
uniprot id: A0A3B4D8Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

42514:ca10a
gene id: 42514:ca10a
uniprot id: A0A3B4C080
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

42514:kif26ab
gene id: 42514:kif26ab
uniprot id: A0A3B4DM82
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:LOC108441172
gene id: 42514:LOC108441172
uniprot id: A0A3B4ECM4
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

42514:LOC108412428
gene id: 42514:LOC108412428
uniprot id: A0A3B4DN01
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:slc10a2
gene id: 42514:slc10a2
uniprot id: A0A3B4D544
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

42514:hoxb8a
gene id: 42514:hoxb8a
uniprot id: A0A3B4DYF0
names: Subcellular Location Annotation
messages: Nucleus

42514:calcrlb
gene id: 42514:calcrlb
uniprot id: A0A3B4EF28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP). Receptor specificity may be modulated by accessory proteins. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

42514:im:6904045
gene id: 42514:im:6904045
uniprot id: A0A3B4C6Q8
names: Similarity
messages: Belongs to the NATD1 family.

42514:gtf2f2b
gene id: 42514:gtf2f2b
uniprot id: A0A3B4E538
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

42514:sstr2a
gene id: 42514:sstr2a
uniprot id: A0A3B4EEA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

42514:arl6ip4
gene id: 42514:arl6ip4
uniprot id: A0A3B4CNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

42514:hrasa
gene id: 42514:hrasa
uniprot id: A0A3B4CC61
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:lim2.1
gene id: 42514:lim2.1
uniprot id: A0A3B4E7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

42514:LOC108412458
gene id: 42514:LOC108412458
uniprot id: A0A3B4DPA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

42514:irx4b
gene id: 42514:irx4b
uniprot id: A0A3B4ENT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

42514:rrp12
gene id: 42514:rrp12
uniprot id: A0A3B4DI42
names: Similarity
messages: Belongs to the RRP12 family.

42514:avpr2ab
gene id: 42514:avpr2ab
uniprot id: A0A3B4C8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:pacc1
gene id: 42514:pacc1
uniprot id: A0A3B4E223
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

42514:ppih
gene id: 42514:ppih
uniprot id: A0A3B4ELE8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

42514:nck1b
gene id: 42514:nck1b
uniprot id: A0A3B4ERL9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

42514:si:dkey-199f5.8
gene id: 42514:si:dkey-199f5.8
uniprot id: A0A3B4CWY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

42514:lpar3
gene id: 42514:lpar3
uniprot id: A0A3B4DYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:sec24a
gene id: 42514:sec24a
uniprot id: A0A3B4E0J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

42514:si:dkey-71l1.1
gene id: 42514:si:dkey-71l1.1
uniprot id: A0A3B4DX19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:rpn2
gene id: 42514:rpn2
uniprot id: A0A3B4C843
uniprot id: A0A3B4C847
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

42514:mcm7
gene id: 42514:mcm7
uniprot id: A0A3B4C696
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

42514:LOC108431879
gene id: 42514:LOC108431879
uniprot id: A0A3B4CA53
names: Subcellular Location Annotation
messages: Membrane

42514:tph1a
gene id: 42514:tph1a
uniprot id: A0A3B4DI33
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

42514:trmt11
gene id: 42514:trmt11
uniprot id: A0A3B4DTJ2
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

42514:kpna2
gene id: 42514:kpna2
uniprot id: A0A3B4DL47
names: Similarity
messages: Belongs to the importin alpha family.

42514:LOC108436052
gene id: 42514:LOC108436052
uniprot id: A0A3B4DA23
names: Similarity
messages: Belongs to the HARBI1 family.

42514:vegfd
gene id: 42514:vegfd
uniprot id: A0A3B4CB32
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

42514:LOC108427785
gene id: 42514:LOC108427785
uniprot id: A0A3B4CW40
uniprot id: A0A3B4ED99
uniprot id: A0A3B4EEG4
names: Similarity
messages: Belongs to the BRAG family.

42514:haus1
gene id: 42514:haus1
uniprot id: A0A3B4CNK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

42514:rpp14
gene id: 42514:rpp14
uniprot id: A0A3B4DHC6
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

42514:gja4
gene id: 42514:gja4
uniprot id: A0A3B4BWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:grm8b
gene id: 42514:grm8b
uniprot id: A0A3B4CHX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

42514:LOC108431635
gene id: 42514:LOC108431635
uniprot id: A0A3B4D9E6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

42514:msi2b
gene id: 42514:msi2b
uniprot id: A0A3B4BSZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

42514:epn3a
gene id: 42514:epn3a
uniprot id: A0A3B4CCB9
uniprot id: A0A3B4CE56
names: Similarity
messages: Belongs to the epsin family.

42514:thbs2b
gene id: 42514:thbs2b
uniprot id: A0A3B4DBB5
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tyw1
gene id: 42514:tyw1
uniprot id: A0A3B4DMY9
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

42514:LOC108437072
gene id: 42514:LOC108437072
uniprot id: A0A3B4DU42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ependymin family.
messages: Forms disulfide-linked dimers.
messages: May play a role in neural plasticity. May be involved during axon regeneration.
messages: Secreted

42514:dner
gene id: 42514:dner
uniprot id: A0A3B4BNG5
uniprot id: A0A3B4BP13
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:adprhl1
gene id: 42514:adprhl1
uniprot id: A0A3B4DR55
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

42514:polr3b
gene id: 42514:polr3b
uniprot id: A0A3B4E4L5
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

42514:LOC108422667
gene id: 42514:LOC108422667
uniprot id: A0A3B4DVZ1
names: Subcellular Location Annotation
messages: Membrane

42514:chst6
gene id: 42514:chst6
uniprot id: A0A3B4E4B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

42514:usp10
gene id: 42514:usp10
uniprot id: A0A3B4E046
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:LOC108411452
gene id: 42514:LOC108411452
uniprot id: A0A3B4D8U1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

42514:stac
gene id: 42514:stac
uniprot id: A0A3B4CZ34
names: Subcellular Location Annotation
messages: sarcolemma

42514:tpm4a
gene id: 42514:tpm4a
uniprot id: A0A3B4CUW2
uniprot id: A0A3B4CX38
uniprot id: A0A3B4CYP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

42514:oclna
gene id: 42514:oclna
uniprot id: A0A3B4DTC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:pick1
gene id: 42514:pick1
uniprot id: A0A3B4EKC2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

42514:lias
gene id: 42514:lias
uniprot id: A0A3B4EKS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

42514:LOC108424956
gene id: 42514:LOC108424956
uniprot id: A0A3B4CX65
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

42514:spp2
gene id: 42514:spp2
uniprot id: A0A3B4C0N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

42514:hnf4a
gene id: 42514:hnf4a
uniprot id: A0A3B4CSG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:ywhah
gene id: 42514:ywhah
uniprot id: A0A3B4CXZ8
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

42514:cdkn1ca
gene id: 42514:cdkn1ca
uniprot id: A0A3B4CJ33
names: Similarity
messages: Belongs to the CDI family.

42514:vps11
gene id: 42514:vps11
uniprot id: A0A3B4DL62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS11 family.
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: autophagosome
messages: clathrin-coated vesicle

42514:tmem242
gene id: 42514:tmem242
uniprot id: A0A3B4EI56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

42514:phpt1
gene id: 42514:phpt1
uniprot id: A0A3B4EII6
names: Function
names: Similarity
messages: Belongs to the janus family.
messages: Exhibits phosphohistidine phosphatase activity.

42514:osbpl11
gene id: 42514:osbpl11
uniprot id: A0A3B4C9R0
names: Similarity
messages: Belongs to the OSBP family.

42514:gsta.1
gene id: 42514:gsta.1
uniprot id: A0A3B4D6V5
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

42514:LOC108439788
gene id: 42514:LOC108439788
uniprot id: A0A3B4DRF5
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

42514:polb
gene id: 42514:polb
uniprot id: A0A3B4DF25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

42514:LOC108423762
gene id: 42514:LOC108423762
uniprot id: A0A3B4CNS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

42514:orai1a
gene id: 42514:orai1a
uniprot id: A0A3B4D8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

42514:arsj
gene id: 42514:arsj
uniprot id: A0A3B4CSP3
names: Similarity
messages: Belongs to the sulfatase family.

42514:LOC108436364
gene id: 42514:LOC108436364
uniprot id: A0A3B4C438
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

42514:im:7150988
gene id: 42514:im:7150988
uniprot id: A0A3B4D3C9
names: Similarity
messages: Belongs to the CRISP family.

42514:LOC108432802
gene id: 42514:LOC108432802
uniprot id: A0A3B4EC98
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:svopl
gene id: 42514:svopl
uniprot id: A0A3B4BUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

42514:arglu1a
gene id: 42514:arglu1a
uniprot id: A0A3B4DW77
names: Similarity
messages: Belongs to the UPF0430 family.

42514:pkp4
gene id: 42514:pkp4
uniprot id: A0A3B4D1P1
names: Similarity
messages: Belongs to the beta-catenin family.

42514:btk
gene id: 42514:btk
uniprot id: A0A3B4E5P4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:mylk5
gene id: 42514:mylk5
uniprot id: A0A3B4CGH4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

42514:cdk5r2b
gene id: 42514:cdk5r2b
uniprot id: A0A3B4C5Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Membrane

42514:myo16
gene id: 42514:myo16
uniprot id: A0A3B4BSQ4
uniprot id: A0A3B4BW27
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:hdac7a
gene id: 42514:hdac7a
uniprot id: A0A3B4DRS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

42514:sdhc
gene id: 42514:sdhc
uniprot id: A0A3B4CXL4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

42514:wnt11f2
gene id: 42514:wnt11f2
uniprot id: A0A3B4D3V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:kin
gene id: 42514:kin
uniprot id: A0A3B4DKN5
names: Similarity
messages: Belongs to the KIN17 family.

42514:rpl13
gene id: 42514:rpl13
uniprot id: A0A3B4CB31
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

42514:chd1l
gene id: 42514:chd1l
uniprot id: A0A3B4DQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

42514:b3gat3
gene id: 42514:b3gat3
uniprot id: A0A3B4E956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:sbds
gene id: 42514:sbds
uniprot id: A0A3B4BUI8
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

42514:gpc1b
gene id: 42514:gpc1b
uniprot id: A0A3B4DUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

42514:cdk15
gene id: 42514:cdk15
uniprot id: A0A3B4CZ69
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:nploc4
gene id: 42514:nploc4
uniprot id: A0A3B4DSR4
names: Similarity
messages: Belongs to the NPL4 family.

42514:LOC108412327
gene id: 42514:LOC108412327
uniprot id: A0A3B4C5M6
names: Subcellular Location Annotation
messages: Membrane

42514:fam136a
gene id: 42514:fam136a
uniprot id: A0A3B4DND9
names: Similarity
messages: Belongs to the FAM136 family.

42514:exo1
gene id: 42514:exo1
uniprot id: A0A3B4C0G6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

42514:ptprb
gene id: 42514:ptprb
uniprot id: A0A3B4EBT4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

42514:aldh6a1
gene id: 42514:aldh6a1
uniprot id: A0A3B4CFU5
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

42514:cct3
gene id: 42514:cct3
uniprot id: A0A3B4DE71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

42514:LOC108442081
gene id: 42514:LOC108442081
uniprot id: A0A3B4BLY2
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

42514:phactr2
gene id: 42514:phactr2
uniprot id: A0A3B4CF17
uniprot id: A0A3B4CF41
uniprot id: A0A3B4CG79
uniprot id: A0A3B4CHF4
uniprot id: A0A3B4E0X2
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

42514:lsm5
gene id: 42514:lsm5
uniprot id: A0A3B4DPX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

42514:si:ch211-181l5.2
gene id: 42514:si:ch211-181l5.2
uniprot id: A0A3B4C0T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:plekha8
gene id: 42514:plekha8
uniprot id: A0A3B4BTA4
names: Subcellular Location Annotation
messages: trans-Golgi network membrane

42514:slc35a3b
gene id: 42514:slc35a3b
uniprot id: A0A3B4E3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:LOC108437555
gene id: 42514:LOC108437555
uniprot id: A0A3B4CAF9
names: Similarity
messages: Belongs to the peptidase S9A family.

42514:dok1a
gene id: 42514:dok1a
uniprot id: A0A3B4CJY8
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

42514:wdr12
gene id: 42514:wdr12
uniprot id: A0A3B4CZP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

42514:prkab1b
gene id: 42514:prkab1b
uniprot id: A0A3B4EJH0
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

42514:ano3
gene id: 42514:ano3
uniprot id: A0A3B4BQH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

42514:ufl1
gene id: 42514:ufl1
uniprot id: A0A3B4EBY6
names: Similarity
messages: Belongs to the UFL1 family.

42514:slc34a1a
gene id: 42514:slc34a1a
uniprot id: A0A3B4BZ15
uniprot id: A0A3B4DQ28
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

42514:shfl
gene id: 42514:shfl
uniprot id: A0A3B4E2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHFL family.
messages: Cytoplasm
messages: Nucleus

42514:fsip1
gene id: 42514:fsip1
uniprot id: A0A3B4EAT8
names: Similarity
messages: Belongs to the FSIP1 family.

42514:LOC108426626
gene id: 42514:LOC108426626
uniprot id: A0A3B4CVV3
names: Similarity
messages: Belongs to the PHYHIP family.

42514:fgd6
gene id: 42514:fgd6
uniprot id: A0A3B4DI35
names: Subcellular Location Annotation
messages: cytoskeleton

42514:LOC108438908
gene id: 42514:LOC108438908
uniprot id: A0A3B4CZB5
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:pde1cb
gene id: 42514:pde1cb
uniprot id: A0A3B4DSG3
uniprot id: A0A3B4DV54
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:tuba5
gene id: 42514:tuba5
uniprot id: A0A3B4CKT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:trpc4b
gene id: 42514:trpc4b
uniprot id: A0A3B4BQD8
names: Subcellular Location Annotation
messages: Membrane

42514:jpt2
gene id: 42514:jpt2
uniprot id: A0A3B4C7F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

42514:LOC108442529
gene id: 42514:LOC108442529
uniprot id: A0A3B4DSG0
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:LOC108427396
gene id: 42514:LOC108427396
uniprot id: A0A3B4CIT0
names: Similarity
messages: Belongs to the intermediate filament family.

42514:dnajb12b
gene id: 42514:dnajb12b
uniprot id: A0A3B4BRF6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:slc25a10
gene id: 42514:slc25a10
uniprot id: A0A3B4CDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:phyhiplb
gene id: 42514:phyhiplb
uniprot id: A0A3B4CPA7
uniprot id: A0A3B4E8L7
names: Similarity
messages: Belongs to the PHYHIP family.

42514:zgc:112052
gene id: 42514:zgc:112052
uniprot id: A0A3B4ECT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

42514:stradb
gene id: 42514:stradb
uniprot id: A0A3B4CA54
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

42514:nfe2l2b
gene id: 42514:nfe2l2b
uniprot id: A0A3B4DWL9
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

42514:zfyve26
gene id: 42514:zfyve26
uniprot id: A0A3B4C8A9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with AP5Z1, AP5B1, AP5S1 and SPG11. Interacts with TTC19 and KIF13A.
messages: Midbody
messages: Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair.

42514:rars2
gene id: 42514:rars2
uniprot id: A0A3B4BNT1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

42514:LOC108427159
gene id: 42514:LOC108427159
uniprot id: A0A3B4DAB7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:cdc42
gene id: 42514:cdc42
uniprot id: A0A3B4DQJ9
uniprot id: A0A3B4DS12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

42514:si:ch1073-280e3.1
gene id: 42514:si:ch1073-280e3.1
uniprot id: A0A3B4C3E6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:LOC108436230
gene id: 42514:LOC108436230
uniprot id: A0A3B4CKS8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

42514:slc9a1a
gene id: 42514:slc9a1a
uniprot id: A0A3B4DP58
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

42514:atp1a3a
gene id: 42514:atp1a3a
uniprot id: A0A3B4DP57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

42514:nrp2b
gene id: 42514:nrp2b
uniprot id: A0A3B4C1W9
uniprot id: A0A3B4DSS4
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:rce1a
gene id: 42514:rce1a
uniprot id: A0A3B4DWN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:sema4f
gene id: 42514:sema4f
uniprot id: A0A3B4BXF5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108431241
gene id: 42514:LOC108431241
uniprot id: A0A3B4BSA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:sft2d2a
gene id: 42514:sft2d2a
uniprot id: A0A3B4DST5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

42514:cebpb
gene id: 42514:cebpb
uniprot id: A0A3B4CMY8
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

42514:stim2b
gene id: 42514:stim2b
uniprot id: A0A3B4DT94
names: Subcellular Location Annotation
messages: Membrane

42514:mrps33
gene id: 42514:mrps33
uniprot id: A0A3B4BUE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

42514:ccdc43
gene id: 42514:ccdc43
uniprot id: A0A3B4CKH7
names: Similarity
messages: Belongs to the CCDC43 family.

42514:slc12a1
gene id: 42514:slc12a1
uniprot id: A0A3B4EKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:eif2b2
gene id: 42514:eif2b2
uniprot id: A0A3B4CV64
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

42514:tspan9a
gene id: 42514:tspan9a
uniprot id: A0A3B4CU98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:pxna
gene id: 42514:pxna
uniprot id: A0A3B4EMY2
uniprot id: A0A3B4EMZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
messages: Nucleus matrix
messages: The LD (leucine and aspartate-rich) motif 3 mediates interaction with GIT1 and functions as a nuclear export signal.
messages: cytoskeleton
messages: focal adhesion

42514:haus3
gene id: 42514:haus3
uniprot id: A0A3B4EAV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

42514:chrna10a
gene id: 42514:chrna10a
uniprot id: A0A3B4E1L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:eef1db
gene id: 42514:eef1db
uniprot id: A0A3B4BRM1
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

42514:dsc2l
gene id: 42514:dsc2l
uniprot id: A0A3B4EJV7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

42514:drd2b
gene id: 42514:drd2b
uniprot id: A0A3B4CGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:LOC108441034
gene id: 42514:LOC108441034
uniprot id: A0A3B4DEB7
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

42514:taf13
gene id: 42514:taf13
uniprot id: A0A3B4CLX7
names: Subcellular Location Annotation
messages: Nucleus

42514:si:ch1073-174d20.2
gene id: 42514:si:ch1073-174d20.2
uniprot id: A0A3B4CH69
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

42514:kcnj12b
gene id: 42514:kcnj12b
uniprot id: A0A3B4C5I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

42514:kcnd1
gene id: 42514:kcnd1
uniprot id: A0A3B4D7R2
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

42514:gprc5c
gene id: 42514:gprc5c
uniprot id: A0A3B4C1R4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:LOC108413555
gene id: 42514:LOC108413555
uniprot id: A0A3B4E0Q9
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

42514:zgc:194665
gene id: 42514:zgc:194665
uniprot id: A0A3B4CR28
names: Similarity
messages: Belongs to the TMEM178 family.

42514:LOC108414553
gene id: 42514:LOC108414553
uniprot id: A0A3B4EFH8
names: Similarity
messages: Belongs to the MHC class I family.

42514:slc19a1
gene id: 42514:slc19a1
uniprot id: A0A3B4DLP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

42514:baiap2a
gene id: 42514:baiap2a
uniprot id: A0A3B4D1F2
uniprot id: A0A3B4EDX0
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

42514:rps27a
gene id: 42514:rps27a
uniprot id: A0A3B4CB12
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

42514:trim69
gene id: 42514:trim69
uniprot id: A0A3B4CN42
names: Subcellular Location Annotation
messages: Cytoplasm

42514:olfml3a
gene id: 42514:olfml3a
uniprot id: A0A3B4EBC2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ada2a
gene id: 42514:ada2a
uniprot id: A0A3B4BXA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

42514:gcgra
gene id: 42514:gcgra
uniprot id: A0A3B4E024
names: Subcellular Location Annotation
messages: Membrane

42514:cluha
gene id: 42514:cluha
uniprot id: A0A3B4BVS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

42514:LOC108436389
gene id: 42514:LOC108436389
uniprot id: A0A3B4C1D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

42514:acvr1ba
gene id: 42514:acvr1ba
uniprot id: A0A3B4EDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:cct4
gene id: 42514:cct4
uniprot id: A0A3B4DVE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

42514:LOC108440930
gene id: 42514:LOC108440930
uniprot id: A0A3B4BYQ0
names: Similarity
messages: Belongs to the TTC9 family.

42514:ino80c
gene id: 42514:ino80c
uniprot id: A0A3B4D7Z7
names: Subcellular Location Annotation
messages: Nucleus

42514:tdo2b
gene id: 42514:tdo2b
uniprot id: A0A3B4E269
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:plaua
gene id: 42514:plaua
uniprot id: A0A3B4E0G0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:mrpl52
gene id: 42514:mrpl52
uniprot id: A0A3B4CZD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

42514:LOC108424690
gene id: 42514:LOC108424690
uniprot id: A0A3B4ER22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

42514:si:ch211-146m13.3
gene id: 42514:si:ch211-146m13.3
uniprot id: A0A3B4CWW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:zdhhc21
gene id: 42514:zdhhc21
uniprot id: A0A3B4CGG9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:senp8
gene id: 42514:senp8
uniprot id: A0A3B4EC26
names: Similarity
messages: Belongs to the peptidase C48 family.

42514:si:ch211-153b23.4
gene id: 42514:si:ch211-153b23.4
uniprot id: A0A3B4CSF8
names: Similarity
messages: Belongs to the SUA5 family.

42514:g6pca.2
gene id: 42514:g6pca.2
uniprot id: A0A3B4DJ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

42514:chrna3
gene id: 42514:chrna3
uniprot id: A0A3B4BP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:tfdp1a
gene id: 42514:tfdp1a
uniprot id: A0A3B4CSL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

42514:ensab
gene id: 42514:ensab
uniprot id: A0A3B4C2W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

42514:naa38
gene id: 42514:naa38
uniprot id: A0A3B4CRS2
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

42514:tmem163b
gene id: 42514:tmem163b
uniprot id: A0A3B4DXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

42514:asip1
gene id: 42514:asip1
uniprot id: A0A3B4C541
names: Subcellular Location Annotation
messages: Secreted

42514:pdha1b
gene id: 42514:pdha1b
uniprot id: A0A3B4CV91
uniprot id: A0A3B4CVE1
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

42514:npnta
gene id: 42514:npnta
uniprot id: A0A3B4CNF9
uniprot id: A0A3B4CQC5
uniprot id: A0A3B4E9B1
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:bbs7
gene id: 42514:bbs7
uniprot id: A0A3B4DAQ5
names: Function
names: Subunit
messages: Part of BBSome complex.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.

42514:fan1
gene id: 42514:fan1
uniprot id: A0A3B4CIM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

42514:ppie
gene id: 42514:ppie
uniprot id: A0A3B4EHW2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

42514:ywhag1
gene id: 42514:ywhag1
uniprot id: A0A3B4DMY0
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

42514:nudcd1
gene id: 42514:nudcd1
uniprot id: A0A3B4CUT5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:irf1b
gene id: 42514:irf1b
uniprot id: A0A3B4E2R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

42514:gpat4
gene id: 42514:gpat4
uniprot id: A0A3B4CLP5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:tfcp2
gene id: 42514:tfcp2
uniprot id: A0A3B4EDS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

42514:pvalb7
gene id: 42514:pvalb7
uniprot id: A0A3B4D9M3
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

42514:LOC108411439
gene id: 42514:LOC108411439
uniprot id: A0A3B4DD92
names: Similarity
messages: Belongs to the actin family.

42514:map3k15
gene id: 42514:map3k15
uniprot id: A0A3B4BPD5
uniprot id: A0A3B4DJV4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

42514:fdps
gene id: 42514:fdps
uniprot id: A0A3B4E7H0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

42514:jagn1a
gene id: 42514:jagn1a
uniprot id: A0A3B4BMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:snx19a
gene id: 42514:snx19a
uniprot id: A0A3B4DTK1
names: Similarity
messages: Belongs to the sorting nexin family.

42514:tmpoa
gene id: 42514:tmpoa
uniprot id: A0A3B4E216
names: Similarity
messages: Belongs to the LEM family.

42514:tacr1a
gene id: 42514:tacr1a
uniprot id: A0A3B4EE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:rbm47
gene id: 42514:rbm47
uniprot id: A0A3B4BR56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Cytoplasm
messages: Nucleus

42514:LOC108431378
gene id: 42514:LOC108431378
uniprot id: A0A3B4BZN0
uniprot id: A0A3B4DRW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

42514:st6gal2a
gene id: 42514:st6gal2a
uniprot id: A0A3B4BWF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:hlfb
gene id: 42514:hlfb
uniprot id: A0A3B4C6E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

42514:fam189b
gene id: 42514:fam189b
uniprot id: A0A3B4EM77
names: Similarity
messages: Belongs to the ENTREP family.

42514:LOC108438821
gene id: 42514:LOC108438821
uniprot id: A0A3B4DBD3
names: Subcellular Location Annotation
messages: Nucleus

42514:irx1a
gene id: 42514:irx1a
uniprot id: A0A3B4C6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

42514:gpr61l
gene id: 42514:gpr61l
uniprot id: A0A3B4E206
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108428455
gene id: 42514:LOC108428455
uniprot id: A0A3B4DXS7
uniprot id: A0A3B4E0K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

42514:LOC108432438
gene id: 42514:LOC108432438
uniprot id: A0A3B4DTY7
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

42514:c26h1orf74
gene id: 42514:c26h1orf74
uniprot id: A0A3B4CK69
names: Similarity
messages: Belongs to the UPF0739 family.

42514:dnmt3ab
gene id: 42514:dnmt3ab
uniprot id: A0A3B4CHA8
uniprot id: A0A3B4E3S4
uniprot id: A0A3B4E430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

42514:evlb
gene id: 42514:evlb
uniprot id: A0A3B4CTD1
uniprot id: A0A3B4E674
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

42514:LOC108441166
gene id: 42514:LOC108441166
uniprot id: A0A3B4CZV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

42514:tmem121ab
gene id: 42514:tmem121ab
uniprot id: A0A3B4C3Q2
names: Similarity
messages: Belongs to the TMEM121 family.

42514:LOC108423941
gene id: 42514:LOC108423941
uniprot id: A0A3B4CAP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

42514:rdh8a
gene id: 42514:rdh8a
uniprot id: A0A3B4E2T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

42514:prdx2
gene id: 42514:prdx2
uniprot id: A0A3B4CWX0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

42514:adam19b
gene id: 42514:adam19b
uniprot id: A0A3B4EET4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:lhx8a
gene id: 42514:lhx8a
uniprot id: A0A3B4DD27
uniprot id: A0A3B4DEB9
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108435733
gene id: 42514:LOC108435733
uniprot id: A0A3B4CML8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:h3f3d
gene id: 42514:h3f3d
uniprot id: A0A3B4BZQ6
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:entpd6
gene id: 42514:entpd6
uniprot id: A0A3B4EHS2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

42514:bcl2b
gene id: 42514:bcl2b
uniprot id: A0A3B4CHC5
names: Similarity
messages: Belongs to the Bcl-2 family.

42514:top1
gene id: 42514:top1
uniprot id: A0A3B4EDA2
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

42514:khdrbs1b
gene id: 42514:khdrbs1b
uniprot id: A0A3B4EMT1
names: Similarity
messages: Belongs to the KHDRBS family.

42514:LOC108429215
gene id: 42514:LOC108429215
uniprot id: A0A3B4DVM9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:p2rx3a
gene id: 42514:p2rx3a
uniprot id: A0A3B4EKX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

42514:ago2
gene id: 42514:ago2
uniprot id: A0A3B4EQ06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Note that the trimeric RLC/miRLC is also referred to as RISC.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

42514:adra2b
gene id: 42514:adra2b
uniprot id: A0A3B4E845
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:abcc3
gene id: 42514:abcc3
uniprot id: A0A3B4BRV6
uniprot id: A0A3B4DMT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

42514:ikbkb
gene id: 42514:ikbkb
uniprot id: A0A3B4BLN7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:LOC108439021
gene id: 42514:LOC108439021
uniprot id: A0A3B4CLA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:scpep1
gene id: 42514:scpep1
uniprot id: A0A3B4CCC0
names: Similarity
messages: Belongs to the peptidase S10 family.

42514:gpr182
gene id: 42514:gpr182
uniprot id: A0A3B4CUP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:map7a
gene id: 42514:map7a
uniprot id: A0A3B4D4B7
names: Similarity
messages: Belongs to the MAP7 family.

42514:pygmb
gene id: 42514:pygmb
uniprot id: A0A3B4C9Y7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

42514:actc1a
gene id: 42514:actc1a
uniprot id: A0A3B4EEV7
names: Similarity
messages: Belongs to the actin family.

42514:parp6b
gene id: 42514:parp6b
uniprot id: A0A3B4CEC5
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:si:dkey-183j2.10
gene id: 42514:si:dkey-183j2.10
uniprot id: A0A3B4CMV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:ypel5
gene id: 42514:ypel5
uniprot id: A0A3B4C4Y7
names: Similarity
messages: Belongs to the yippee family.

42514:elapor2a
gene id: 42514:elapor2a
uniprot id: A0A3B4EDR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

42514:fgfr1op2
gene id: 42514:fgfr1op2
uniprot id: A0A3B4CLT1
names: Similarity
messages: Belongs to the SIKE family.

42514:stat1b
gene id: 42514:stat1b
uniprot id: A0A3B4CW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

42514:chrm3a
gene id: 42514:chrm3a
uniprot id: A0A3B4DAG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

42514:cth1
gene id: 42514:cth1
uniprot id: A0A3B4C8S2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

42514:tent5ba
gene id: 42514:tent5ba
uniprot id: A0A3B4CXD4
names: Similarity
messages: Belongs to the TENT family.

42514:LOC108434887
gene id: 42514:LOC108434887
uniprot id: A0A3B4C3I5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:dolpp1
gene id: 42514:dolpp1
uniprot id: A0A3B4CHA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

42514:rundc3ab
gene id: 42514:rundc3ab
uniprot id: A0A3B4BXC3
names: Similarity
messages: Belongs to the RUNDC3 family.

42514:abhd2a
gene id: 42514:abhd2a
uniprot id: A0A3B4DW67
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

42514:itm2cb
gene id: 42514:itm2cb
uniprot id: A0A3B4DDN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

42514:LOC108441202
gene id: 42514:LOC108441202
uniprot id: A0A3B4E9A7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

42514:lhx2b
gene id: 42514:lhx2b
uniprot id: A0A3B4BM34
names: Subcellular Location Annotation
messages: Nucleus

42514:agtr2
gene id: 42514:agtr2
uniprot id: A0A3B4BPX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:rhebl1
gene id: 42514:rhebl1
uniprot id: A0A3B4E6J2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:cds1
gene id: 42514:cds1
uniprot id: A0A3B4E9N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

42514:pax7a
gene id: 42514:pax7a
uniprot id: A0A3B4EMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

42514:aldh3b1
gene id: 42514:aldh3b1
uniprot id: A0A3B4D2H8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

42514:slc6a1l
gene id: 42514:slc6a1l
uniprot id: A0A3B4EPC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:ntn1b
gene id: 42514:ntn1b
uniprot id: A0A3B4BNG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:erap2
gene id: 42514:erap2
uniprot id: A0A3B4DGR8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

42514:unga
gene id: 42514:unga
uniprot id: A0A3B4E9F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

42514:ppp3cca
gene id: 42514:ppp3cca
uniprot id: A0A3B4CZV4
uniprot id: A0A3B4EDY9
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

42514:hsc70
gene id: 42514:hsc70
uniprot id: A0A3B4CCA1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:sirt4
gene id: 42514:sirt4
uniprot id: A0A3B4CGX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

42514:gfm2
gene id: 42514:gfm2
uniprot id: A0A3B4E623
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

42514:LOC108444261
gene id: 42514:LOC108444261
uniprot id: A0A3B4DWW4
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

42514:wnk4b
gene id: 42514:wnk4b
uniprot id: A0A3B4E6U6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

42514:tfpi2
gene id: 42514:tfpi2
uniprot id: A0A3B4BR12
names: Subcellular Location Annotation
messages: Secreted

42514:itga2b
gene id: 42514:itga2b
uniprot id: A0A3B4C8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

42514:LOC108411165
gene id: 42514:LOC108411165
uniprot id: A0A3B4CDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

42514:zgc:56095
gene id: 42514:zgc:56095
uniprot id: A0A3B4D7V7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

42514:vipb
gene id: 42514:vipb
uniprot id: A0A3B4DK94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

42514:itgb1a
gene id: 42514:itgb1a
uniprot id: A0A3B4BN45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

42514:rfc5
gene id: 42514:rfc5
uniprot id: A0A3B4E910
names: Similarity
messages: Belongs to the activator 1 small subunits family.

42514:hs3st3b1a
gene id: 42514:hs3st3b1a
uniprot id: A0A3B4D2I3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:sh3bgrl
gene id: 42514:sh3bgrl
uniprot id: A0A3B4DUE4
names: Similarity
messages: Belongs to the SH3BGR family.

42514:eif2a
gene id: 42514:eif2a
uniprot id: A0A3B4EDR2
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

42514:smad2
gene id: 42514:smad2
uniprot id: A0A3B4D7F9
uniprot id: A0A3B4DA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:pex16
gene id: 42514:pex16
uniprot id: A0A3B4E877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

42514:LOC108424345
gene id: 42514:LOC108424345
uniprot id: A0A3B4CX71
uniprot id: A0A3B4CX91
uniprot id: A0A3B4CYV9
uniprot id: A0A3B4EC74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tasp1
gene id: 42514:tasp1
uniprot id: A0A3B4DEP1
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

42514:fars2
gene id: 42514:fars2
uniprot id: A0A3B4BMM2
uniprot id: A0A3B4DJU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

42514:aebp1
gene id: 42514:aebp1
uniprot id: A0A3B4D6A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

42514:lbx1a
gene id: 42514:lbx1a
uniprot id: A0A3B4DMD5
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108427968
gene id: 42514:LOC108427968
uniprot id: A0A3B4E2C6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108434426
gene id: 42514:LOC108434426
uniprot id: A0A3B4CS35
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:tnfsf10l3
gene id: 42514:tnfsf10l3
uniprot id: A0A3B4C9S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

42514:cacng2a
gene id: 42514:cacng2a
uniprot id: A0A3B4DFR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

42514:zcchc8
gene id: 42514:zcchc8
uniprot id: A0A3B4CS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

42514:ppm1da
gene id: 42514:ppm1da
uniprot id: A0A3B4BT73
names: Similarity
messages: Belongs to the PP2C family.

42514:LOC108411498
gene id: 42514:LOC108411498
uniprot id: A0A3B4CXV6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

42514:slc13a1
gene id: 42514:slc13a1
uniprot id: A0A3B4CGL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

42514:irx1b
gene id: 42514:irx1b
uniprot id: A0A3B4ER16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

42514:ptprsa
gene id: 42514:ptprsa
uniprot id: A0A3B4D0G0
uniprot id: A0A3B4D0Z0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

42514:klhl15
gene id: 42514:klhl15
uniprot id: A0A3B4CLL1
uniprot id: A0A3B4E5I3
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108442834
gene id: 42514:LOC108442834
uniprot id: A0A3B4D6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

42514:il17c
gene id: 42514:il17c
uniprot id: A0A3B4E4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

42514:cul4b
gene id: 42514:cul4b
uniprot id: A0A3B4CWM0
names: Similarity
messages: Belongs to the cullin family.

42514:arpp19b
gene id: 42514:arpp19b
uniprot id: A0A3B4BPQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

42514:fam234b
gene id: 42514:fam234b
uniprot id: A0A3B4EFQ6
names: Similarity
messages: Belongs to the FAM234 family.

42514:fer
gene id: 42514:fer
uniprot id: A0A3B4BSK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

42514:mrpl54
gene id: 42514:mrpl54
uniprot id: A0A3B4BKL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

42514:LOC108443957
gene id: 42514:LOC108443957
uniprot id: A0A3B4EP34
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

42514:gosr1
gene id: 42514:gosr1
uniprot id: A0A3B4BTS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

42514:katna1
gene id: 42514:katna1
uniprot id: A0A3B4DVS6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

42514:rpn1
gene id: 42514:rpn1
uniprot id: A0A3B4C6T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

42514:p2rx5
gene id: 42514:p2rx5
uniprot id: A0A3B4DQB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

42514:shbg
gene id: 42514:shbg
uniprot id: A0A3B4C1F9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:prkab2
gene id: 42514:prkab2
uniprot id: A0A3B4C4J4
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

42514:LOC108440653
gene id: 42514:LOC108440653
uniprot id: A0A3B4CPH5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:zc2hc1c
gene id: 42514:zc2hc1c
uniprot id: A0A3B4DMW3
names: Similarity
messages: Belongs to the ZC2HC1 family.

42514:LOC108424729
gene id: 42514:LOC108424729
uniprot id: A0A3B4BKE9
uniprot id: A0A3B4BP83
names: Similarity
messages: Belongs to the apolipoprotein L family.

42514:mlst8
gene id: 42514:mlst8
uniprot id: A0A3B4C031
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of TORC1 complex. Part of the TORC2 complex.
messages: Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals.

42514:nat15
gene id: 42514:nat15
uniprot id: A0A3B4EC72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

42514:serpinf2a
gene id: 42514:serpinf2a
uniprot id: A0A3B4C9R7
names: Similarity
messages: Belongs to the serpin family.

42514:idh3b
gene id: 42514:idh3b
uniprot id: A0A3B4CGC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

42514:dpy30
gene id: 42514:dpy30
uniprot id: A0A3B4E0B8
names: Similarity
messages: Belongs to the dpy-30 family.

42514:lamb4
gene id: 42514:lamb4
uniprot id: A0A3B4E3J2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

42514:mat2ab
gene id: 42514:mat2ab
uniprot id: A0A3B4CLL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

42514:zgc:112271
gene id: 42514:zgc:112271
uniprot id: A0A3B4CJK8
names: Similarity
messages: Belongs to the BolA/IbaG family.

42514:stard13b
gene id: 42514:stard13b
uniprot id: A0A3B4BPP6
uniprot id: A0A3B4DJQ8
uniprot id: A0A3B4DJT6
uniprot id: A0A3B4DLC1
names: Subcellular Location Annotation
messages: Cytoplasm

42514:adrb3b
gene id: 42514:adrb3b
uniprot id: A0A3B4E606
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108428237
gene id: 42514:LOC108428237
uniprot id: A0A3B4CZL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

42514:gas8
gene id: 42514:gas8
uniprot id: A0A3B4DDQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum
messages: flagellum axoneme

42514:rorc
gene id: 42514:rorc
uniprot id: A0A3B4CUX9
uniprot id: A0A3B4CVK3
uniprot id: A0A3B4E799
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:pik3r1
gene id: 42514:pik3r1
uniprot id: A0A3B4DDM2
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

42514:LOC108423767
gene id: 42514:LOC108423767
uniprot id: A0A3B4CGL5
names: Subcellular Location Annotation
messages: Membrane

42514:hoxd10a
gene id: 42514:hoxd10a
uniprot id: A0A3B4ECD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

42514:gpsm2
gene id: 42514:gpsm2
uniprot id: A0A3B4CM69
uniprot id: A0A3B4E4C0
names: Similarity
messages: Belongs to the GPSM family.

42514:fam167aa
gene id: 42514:fam167aa
uniprot id: A0A3B4CNK3
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

42514:zgc:112332
gene id: 42514:zgc:112332
uniprot id: A0A3B4CNK2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:dnaja
gene id: 42514:dnaja
uniprot id: A0A3B4C6Z1
names: Subcellular Location Annotation
messages: Membrane

42514:si:ch211-130m23.3
gene id: 42514:si:ch211-130m23.3
uniprot id: A0A3B4DXR7
names: Subcellular Location Annotation
messages: Nucleus

42514:setd7
gene id: 42514:setd7
uniprot id: A0A3B4DFK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
messages: Nucleus

42514:rnft1
gene id: 42514:rnft1
uniprot id: A0A3B4DSD7
names: Subcellular Location Annotation
messages: Membrane

42514:neto1l
gene id: 42514:neto1l
uniprot id: A0A3B4EDU1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tradd
gene id: 42514:tradd
uniprot id: A0A3B4BTQ3
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

42514:LOC108425195
gene id: 42514:LOC108425195
uniprot id: A0A3B4CB84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

42514:arsh
gene id: 42514:arsh
uniprot id: A0A3B4E921
names: Similarity
messages: Belongs to the sulfatase family.

42514:kat2b
gene id: 42514:kat2b
uniprot id: A0A3B4EEG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

42514:pax8
gene id: 42514:pax8
uniprot id: A0A3B4D7H8
uniprot id: A0A3B4EKQ9
names: Subcellular Location Annotation
messages: Nucleus

42514:cdadc1
gene id: 42514:cdadc1
uniprot id: A0A3B4D6D5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

42514:LOC108432634
gene id: 42514:LOC108432634
uniprot id: A0A3B4BQQ5
uniprot id: A0A3B4BQR0
names: Similarity
messages: Belongs to the RRP1 family.

42514:gpr157
gene id: 42514:gpr157
uniprot id: A0A3B4E9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 5 family.
messages: Membrane

42514:gtpbp10
gene id: 42514:gtpbp10
uniprot id: A0A3B4EK47
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

42514:rad51d
gene id: 42514:rad51d
uniprot id: A0A3B4CJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
messages: Nucleus

42514:LOC108443485
gene id: 42514:LOC108443485
uniprot id: A0A3B4CN39
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

42514:exoc4
gene id: 42514:exoc4
uniprot id: A0A3B4DK37
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

42514:rragca
gene id: 42514:rragca
uniprot id: A0A3B4C3T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

42514:zgc:163057
gene id: 42514:zgc:163057
uniprot id: A0A3B4DRC0
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108443093
gene id: 42514:LOC108443093
uniprot id: A0A3B4DVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:LOC108440268
gene id: 42514:LOC108440268
uniprot id: A0A3B4DU04
names: Similarity
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

42514:LOC108423898
gene id: 42514:LOC108423898
uniprot id: A0A3B4CHU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Membrane

42514:igfbp6a
gene id: 42514:igfbp6a
uniprot id: A0A3B4BQR1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:ddx10
gene id: 42514:ddx10
uniprot id: A0A3B4E3S3
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

42514:atic
gene id: 42514:atic
uniprot id: A0A3B4DCA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PurH family.
messages: cytosol

42514:rpl36a
gene id: 42514:rpl36a
uniprot id: A0A3B4BT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Cytoplasm

42514:aadac
gene id: 42514:aadac
uniprot id: A0A3B4DL79
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

42514:alg6
gene id: 42514:alg6
uniprot id: A0A3B4DMV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:elovl4b
gene id: 42514:elovl4b
uniprot id: A0A3B4D782
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Oligomer.

42514:nipal4
gene id: 42514:nipal4
uniprot id: A0A3B4DPI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

42514:lbh
gene id: 42514:lbh
uniprot id: A0A3B4DS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus

42514:rpl18a
gene id: 42514:rpl18a
uniprot id: A0A3B4DN18
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

42514:LOC108424644
gene id: 42514:LOC108424644
uniprot id: A0A3B4BP93
names: Subcellular Location Annotation
messages: Membrane

42514:lhx1b
gene id: 42514:lhx1b
uniprot id: A0A3B4CBP6
names: Subcellular Location Annotation
messages: Nucleus

42514:sfxn5b
gene id: 42514:sfxn5b
uniprot id: A0A3B4D0V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

42514:pif1
gene id: 42514:pif1
uniprot id: A0A3B4DNZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

42514:elf3
gene id: 42514:elf3
uniprot id: A0A3B4BZL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:taf15
gene id: 42514:taf15
uniprot id: A0A3B4BUI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

42514:prph
gene id: 42514:prph
uniprot id: A0A3B4BUR5
names: Similarity
messages: Belongs to the intermediate filament family.

42514:mpi
gene id: 42514:mpi
uniprot id: A0A3B4EHH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

42514:dnal4b
gene id: 42514:dnal4b
uniprot id: A0A3B4DC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

42514:sf3b4
gene id: 42514:sf3b4
uniprot id: A0A3B4DJE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

42514:egr2b
gene id: 42514:egr2b
uniprot id: A0A3B4CSF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

42514:pde6d
gene id: 42514:pde6d
uniprot id: A0A3B4D9G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

42514:zgc:114119
gene id: 42514:zgc:114119
uniprot id: A0A3B4EFS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

42514:pms1
gene id: 42514:pms1
uniprot id: A0A3B4CTE1
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

42514:atp1a3b
gene id: 42514:atp1a3b
uniprot id: A0A3B4CVI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

42514:faah2b
gene id: 42514:faah2b
uniprot id: A0A3B4CUF4
names: Similarity
messages: Belongs to the amidase family.

42514:jupb
gene id: 42514:jupb
uniprot id: A0A3B4EDB0
names: Similarity
messages: Belongs to the beta-catenin family.

42514:LOC108439637
gene id: 42514:LOC108439637
uniprot id: A0A3B4CCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

42514:gabrg2
gene id: 42514:gabrg2
uniprot id: A0A3B4D029
uniprot id: A0A3B4D0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:entpd4
gene id: 42514:entpd4
uniprot id: A0A3B4CQE8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

42514:LOC108413813
gene id: 42514:LOC108413813
uniprot id: A0A3B4BTX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:gabrb1
gene id: 42514:gabrb1
uniprot id: A0A3B4CD53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:chst3a
gene id: 42514:chst3a
uniprot id: A0A3B4DGP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

42514:sec24c
gene id: 42514:sec24c
uniprot id: A0A3B4CYH6
uniprot id: A0A3B4CZY1
uniprot id: A0A3B4D002
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

42514:alas1
gene id: 42514:alas1
uniprot id: A0A3B4BLU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

42514:ints14
gene id: 42514:ints14
uniprot id: A0A3B4E093
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

42514:LOC108435468
gene id: 42514:LOC108435468
uniprot id: A0A3B4DE10
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

42514:acap1
gene id: 42514:acap1
uniprot id: A0A3B4EKP6
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

42514:gbx2
gene id: 42514:gbx2
uniprot id: A0A3B4BSL3
names: Subcellular Location Annotation
messages: Nucleus

42514:otop1
gene id: 42514:otop1
uniprot id: A0A3B4DWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

42514:serpinh1b
gene id: 42514:serpinh1b
uniprot id: A0A3B4E2D6
names: Similarity
messages: Belongs to the serpin family.

42514:mcts1
gene id: 42514:mcts1
uniprot id: A0A3B4EAM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

42514:si:dkey-246i14.3
gene id: 42514:si:dkey-246i14.3
uniprot id: A0A3B4DD04
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:fmc1
gene id: 42514:fmc1
uniprot id: A0A3B4CE39
names: Similarity
messages: Belongs to the FMC1 family.

42514:agpat3
gene id: 42514:agpat3
uniprot id: A0A3B4EI64
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:snx19b
gene id: 42514:snx19b
uniprot id: A0A3B4EJI2
names: Similarity
messages: Belongs to the sorting nexin family.

42514:dmap1
gene id: 42514:dmap1
uniprot id: A0A3B4E6Q3
names: Subcellular Location Annotation
messages: Nucleus

42514:xirp2a
gene id: 42514:xirp2a
uniprot id: A0A3B4CQ80
names: Domain
names: Similarity
messages: Belongs to the Xin family.
messages: Xin repeats bind F-actin.

42514:usp2a
gene id: 42514:usp2a
uniprot id: A0A3B4C1Z9
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:lhfpl2b
gene id: 42514:lhfpl2b
uniprot id: A0A3B4DDY2
names: Subcellular Location Annotation
messages: Membrane

42514:gata6
gene id: 42514:gata6
uniprot id: A0A3B4C4F4
names: Subcellular Location Annotation
messages: Nucleus

42514:mettl14
gene id: 42514:mettl14
uniprot id: A0A3B4DPD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MT-A70-like family.
messages: Heterodimer; heterodimerizes with mettl3 to form an antiparallel heterodimer that constitutes an active methyltransferase.
messages: Nucleus
messages: The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with mettl3, mettl14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing.

42514:LOC108423542
gene id: 42514:LOC108423542
uniprot id: A0A3B4BQB2
uniprot id: A0A3B4DK70
names: Similarity
messages: Belongs to the sorting nexin family.

42514:pdpk1a
gene id: 42514:pdpk1a
uniprot id: A0A3B4DPU2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

42514:maf1b
gene id: 42514:maf1b
uniprot id: A0A3B4DIE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

42514:rbck1
gene id: 42514:rbck1
uniprot id: A0A3B4DHT6
names: Similarity
messages: Belongs to the RBR family.

42514:tnfaip1
gene id: 42514:tnfaip1
uniprot id: A0A3B4C114
names: Similarity
messages: Belongs to the BACURD family.

42514:LOC108436247
gene id: 42514:LOC108436247
uniprot id: A0A3B4E2Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

42514:LOC108415260
gene id: 42514:LOC108415260
uniprot id: A0A3B4BTL5
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:dok2
gene id: 42514:dok2
uniprot id: A0A3B4C799
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

42514:bmp6
gene id: 42514:bmp6
uniprot id: A0A3B4D6I8
names: Similarity
messages: Belongs to the TGF-beta family.

42514:ormdl2
gene id: 42514:ormdl2
uniprot id: A0A3B4DAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

42514:LOC108443332
gene id: 42514:LOC108443332
uniprot id: A0A3B4D995
names: Subcellular Location Annotation
messages: Cytoplasm

42514:slc35a2
gene id: 42514:slc35a2
uniprot id: A0A3B4EIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:spns2
gene id: 42514:spns2
uniprot id: A0A3B4C8S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

42514:mboat2a
gene id: 42514:mboat2a
uniprot id: A0A3B4CMK7
names: Subcellular Location Annotation
messages: Membrane

42514:tjp2a
gene id: 42514:tjp2a
uniprot id: A0A3B4D869
uniprot id: A0A3B4EHJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:nfs1
gene id: 42514:nfs1
uniprot id: A0A3B4DIM2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

42514:fam167ab
gene id: 42514:fam167ab
uniprot id: A0A3B4D9H6
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

42514:padi2
gene id: 42514:padi2
uniprot id: A0A3B4BZ98
uniprot id: A0A3B4DQN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

42514:aldh3a2a
gene id: 42514:aldh3a2a
uniprot id: A0A3B4DR60
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

42514:fgf1b
gene id: 42514:fgf1b
uniprot id: A0A3B4EJM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

42514:ap1m1
gene id: 42514:ap1m1
uniprot id: A0A3B4D2T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

42514:LOC108430423
gene id: 42514:LOC108430423
uniprot id: A0A3B4BPH7
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108416612
gene id: 42514:LOC108416612
uniprot id: A0A3B4CGV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:rps17
gene id: 42514:rps17
uniprot id: A0A3B4CYB3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

42514:LOC108433198
gene id: 42514:LOC108433198
uniprot id: A0A3B4DLY5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:keap1b
gene id: 42514:keap1b
uniprot id: A0A3B4BKD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

42514:rpl39
gene id: 42514:rpl39
uniprot id: A0A3B4CTU9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

42514:LOC108440646
gene id: 42514:LOC108440646
uniprot id: A0A3B4CQU6
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

42514:mcoln1a
gene id: 42514:mcoln1a
uniprot id: A0A3B4EEA1
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

42514:fam20a
gene id: 42514:fam20a
uniprot id: A0A3B4C728
names: Similarity
messages: Belongs to the FAM20 family.

42514:dync1i2a
gene id: 42514:dync1i2a
uniprot id: A0A3B4CQM5
uniprot id: A0A3B4EAW4
names: Similarity
messages: Belongs to the dynein intermediate chain family.

42514:rpl36
gene id: 42514:rpl36
uniprot id: A0A3B4EAM2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

42514:tshz1
gene id: 42514:tshz1
uniprot id: A0A3B4CI23
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

42514:fgfr4
gene id: 42514:fgfr4
uniprot id: A0A3B4E1U6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:myo7ab
gene id: 42514:myo7ab
uniprot id: A0A3B4CFK9
uniprot id: A0A3B4CH44
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:manf
gene id: 42514:manf
uniprot id: A0A3B4D7H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

42514:traf4b
gene id: 42514:traf4b
uniprot id: A0A3B4DZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

42514:elk3
gene id: 42514:elk3
uniprot id: A0A3B4CTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:ednrba
gene id: 42514:ednrba
uniprot id: A0A3B4CF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:oprd1a
gene id: 42514:oprd1a
uniprot id: A0A3B4DSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:phkg1a
gene id: 42514:phkg1a
uniprot id: A0A3B4BNL5
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

42514:actr5
gene id: 42514:actr5
uniprot id: A0A3B4EPE6
names: Similarity
messages: Belongs to the actin family.

42514:si:ch1073-272o11.3
gene id: 42514:si:ch1073-272o11.3
uniprot id: A0A3B4BR07
names: Similarity
messages: Belongs to the CDR2 family.

42514:LOC108433924
gene id: 42514:LOC108433924
uniprot id: A0A3B4D568
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

42514:cnot11
gene id: 42514:cnot11
uniprot id: A0A3B4E9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

42514:mdfic2
gene id: 42514:mdfic2
uniprot id: A0A3B4DKS0
names: Similarity
messages: Belongs to the MDFI family.

42514:tlcd2
gene id: 42514:tlcd2
uniprot id: A0A3B4BSG4
names: Subcellular Location Annotation
messages: Membrane

42514:tbl1x
gene id: 42514:tbl1x
uniprot id: A0A3B4BVK7
names: Similarity
messages: Belongs to the WD repeat EBI family.

42514:lyrm5a
gene id: 42514:lyrm5a
uniprot id: A0A3B4EQI5
names: Similarity
messages: Belongs to the complex I LYR family.

42514:sdc2
gene id: 42514:sdc2
uniprot id: A0A3B4D357
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

42514:slc7a5
gene id: 42514:slc7a5
uniprot id: A0A3B4DRT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

42514:casq2
gene id: 42514:casq2
uniprot id: A0A3B4BS22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

42514:aldocb
gene id: 42514:aldocb
uniprot id: A0A3B4CCE9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

42514:LOC108442132
gene id: 42514:LOC108442132
uniprot id: A0A3B4DM79
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:leprotl1
gene id: 42514:leprotl1
uniprot id: A0A3B4DX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

42514:rab11fip3
gene id: 42514:rab11fip3
uniprot id: A0A3B4DUF4
uniprot id: A0A3B4DVL8
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

42514:diablob
gene id: 42514:diablob
uniprot id: A0A3B4CL24
names: Subcellular Location Annotation
messages: Mitochondrion

42514:adamts2
gene id: 42514:adamts2
uniprot id: A0A3B4DF73
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:si:dkey-206f10.1
gene id: 42514:si:dkey-206f10.1
uniprot id: A0A3B4C7H3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

42514:zgc:112148
gene id: 42514:zgc:112148
uniprot id: A0A3B4DH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

42514:fabp7a
gene id: 42514:fabp7a
uniprot id: A0A3B4D120
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:sept5a
gene id: 42514:sept5a
uniprot id: A0A3B4DIG3
uniprot id: A0A3B4DIH1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

42514:esyt3
gene id: 42514:esyt3
uniprot id: A0A3B4DDN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:gpt2
gene id: 42514:gpt2
uniprot id: A0A3B4CCW5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

42514:pomcb
gene id: 42514:pomcb
uniprot id: A0A3B4C9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

42514:krt94
gene id: 42514:krt94
uniprot id: A0A3B4DU68
names: Similarity
messages: Belongs to the intermediate filament family.

42514:hoxc8a
gene id: 42514:hoxc8a
uniprot id: A0A3B4CSX8
names: Subcellular Location Annotation
messages: Nucleus

42514:trpt1
gene id: 42514:trpt1
uniprot id: A0A3B4BR18
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

42514:slc25a55a
gene id: 42514:slc25a55a
uniprot id: A0A3B4BXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:htatsf1
gene id: 42514:htatsf1
uniprot id: A0A3B4EL12
names: Similarity
messages: Belongs to the HTATSF1 family.

42514:rabggtb
gene id: 42514:rabggtb
uniprot id: A0A3B4C3Z4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

42514:LOC108431810
gene id: 42514:LOC108431810
uniprot id: A0A3B4CN01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

42514:gli2a
gene id: 42514:gli2a
uniprot id: A0A3B4CNG2
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

42514:cetn2
gene id: 42514:cetn2
uniprot id: A0A3B4E3C3
names: Similarity
messages: Belongs to the centrin family.

42514:mrap2a
gene id: 42514:mrap2a
uniprot id: A0A3B4EGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108414116
gene id: 42514:LOC108414116
uniprot id: A0A3B4DIM0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:olfm1b
gene id: 42514:olfm1b
uniprot id: A0A3B4BPF2
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

42514:nkx2.4b
gene id: 42514:nkx2.4b
uniprot id: A0A3B4DQF5
names: Subcellular Location Annotation
messages: Nucleus

42514:sema6a
gene id: 42514:sema6a
uniprot id: A0A3B4BV05
uniprot id: A0A3B4DMY2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:agrn
gene id: 42514:agrn
uniprot id: A0A3B4CPY5
uniprot id: A0A3B4CS22
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:znf330
gene id: 42514:znf330
uniprot id: A0A3B4DCJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

42514:lipca
gene id: 42514:lipca
uniprot id: A0A3B4E7P2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:LOC108433269
gene id: 42514:LOC108433269
uniprot id: A0A3B4DF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:bloc1s5
gene id: 42514:bloc1s5
uniprot id: A0A3B4D3Z3
names: Function
names: Similarity
messages: Belongs to the BLOC1S5 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).

42514:pkp2
gene id: 42514:pkp2
uniprot id: A0A3B4CMB2
names: Similarity
messages: Belongs to the beta-catenin family.

42514:pfkfb2a
gene id: 42514:pfkfb2a
uniprot id: A0A3B4EC52
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

42514:LOC108435091
gene id: 42514:LOC108435091
uniprot id: A0A3B4C8W7
names: Similarity
messages: Belongs to the TGF-beta family.

42514:ankrd13d
gene id: 42514:ankrd13d
uniprot id: A0A3B4D6V9
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

42514:rnf34a
gene id: 42514:rnf34a
uniprot id: A0A3B4CVW1
uniprot id: A0A3B4CVW8
uniprot id: A0A3B4EBN1
names: Subcellular Location Annotation
messages: Cell membrane

42514:dgki
gene id: 42514:dgki
uniprot id: A0A3B4EMX3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

42514:casp8
gene id: 42514:casp8
uniprot id: A0A3B4DL35
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:cdh12a
gene id: 42514:cdh12a
uniprot id: A0A3B4CWZ1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

42514:LOC108440010
gene id: 42514:LOC108440010
uniprot id: A0A3B4D156
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:capn3b
gene id: 42514:capn3b
uniprot id: A0A3B4C6L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ttc39c
gene id: 42514:ttc39c
uniprot id: A0A3B4CWR1
names: Similarity
messages: Belongs to the TTC39 family.

42514:scamp5a
gene id: 42514:scamp5a
uniprot id: A0A3B4E108
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

42514:LOC108410535
gene id: 42514:LOC108410535
uniprot id: A0A3B4CTA8
names: Subcellular Location Annotation
messages: Membrane

42514:coq8ab
gene id: 42514:coq8ab
uniprot id: A0A3B4BL64
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

42514:il12bb
gene id: 42514:il12bb
uniprot id: A0A3B4CMD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

42514:ccr9b
gene id: 42514:ccr9b
uniprot id: A0A3B4CEB1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:arf2b
gene id: 42514:arf2b
uniprot id: A0A3B4CBF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

42514:add2
gene id: 42514:add2
uniprot id: A0A3B4BRQ1
uniprot id: A0A3B4BRU7
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

42514:slc25a6
gene id: 42514:slc25a6
uniprot id: A0A3B4E842
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

42514:endou2
gene id: 42514:endou2
uniprot id: A0A3B4D9N9
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

42514:LOC108440668
gene id: 42514:LOC108440668
uniprot id: A0A3B4E829
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

42514:flvcr1
gene id: 42514:flvcr1
uniprot id: A0A3B4DEV0
names: Subcellular Location Annotation
messages: Membrane

42514:mtg1
gene id: 42514:mtg1
uniprot id: A0A3B4DJK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Mitochondrion inner membrane
messages: Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity.

42514:LOC108436296
gene id: 42514:LOC108436296
uniprot id: A0A3B4CBY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:c28h22orf39
gene id: 42514:c28h22orf39
uniprot id: A0A3B4BQ01
names: Similarity
messages: Belongs to the UPF0545 family.

42514:LOC108442707
gene id: 42514:LOC108442707
uniprot id: A0A3B4DIY3
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:zdhhc11
gene id: 42514:zdhhc11
uniprot id: A0A3B4DMA4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:dohh
gene id: 42514:dohh
uniprot id: A0A3B4CBC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

42514:wnt3
gene id: 42514:wnt3
uniprot id: A0A3B4C0Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:LOC108426744
gene id: 42514:LOC108426744
uniprot id: A0A3B4E0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

42514:mrpl37
gene id: 42514:mrpl37
uniprot id: A0A3B4DDR5
names: Subcellular Location Annotation
messages: Mitochondrion

42514:creb1a
gene id: 42514:creb1a
uniprot id: A0A3B4D3X0
names: Subcellular Location Annotation
messages: Nucleus

42514:snrnp27
gene id: 42514:snrnp27
uniprot id: A0A3B4BNQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

42514:pkz
gene id: 42514:pkz
uniprot id: A0A3B4D2N4
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:cdc34b
gene id: 42514:cdc34b
uniprot id: A0A3B4C3J9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:kif2a
gene id: 42514:kif2a
uniprot id: A0A3B4CPX0
uniprot id: A0A3B4E8Y7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:bcas2
gene id: 42514:bcas2
uniprot id: A0A3B4CFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

42514:mtnr1ab
gene id: 42514:mtnr1ab
uniprot id: A0A3B4D3K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

42514:syt14b
gene id: 42514:syt14b
uniprot id: A0A3B4EH38
names: Similarity
messages: Belongs to the synaptotagmin family.

42514:sbf1
gene id: 42514:sbf1
uniprot id: A0A3B4BVW3
uniprot id: A0A3B4DM61
uniprot id: A0A3B4DMA2
uniprot id: A0A3B4DNF8
uniprot id: A0A3B4DNN1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

42514:twf1a
gene id: 42514:twf1a
uniprot id: A0A3B4CL22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

42514:wasf3a
gene id: 42514:wasf3a
uniprot id: A0A3B4EN44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

42514:bmp16
gene id: 42514:bmp16
uniprot id: A0A3B4ENP1
names: Similarity
messages: Belongs to the TGF-beta family.

42514:maco1b
gene id: 42514:maco1b
uniprot id: A0A3B4CEL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

42514:ppil3
gene id: 42514:ppil3
uniprot id: A0A3B4D8K9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

42514:ranbp9
gene id: 42514:ranbp9
uniprot id: A0A3B4EKF7
names: Similarity
messages: Belongs to the RANBP9/10 family.

42514:sh3bgrl3
gene id: 42514:sh3bgrl3
uniprot id: A0A3B4EHF1
names: Similarity
messages: Belongs to the SH3BGR family.

42514:LOC108413075
gene id: 42514:LOC108413075
uniprot id: A0A3B4C034
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108436163
gene id: 42514:LOC108436163
uniprot id: A0A3B4E677
names: Similarity
messages: Belongs to the SLBP family.

42514:LOC108413312
gene id: 42514:LOC108413312
uniprot id: A0A3B4DAS1
uniprot id: A0A3B4DBT2
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:adcy2b
gene id: 42514:adcy2b
uniprot id: A0A3B4D9W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

42514:tmem59l
gene id: 42514:tmem59l
uniprot id: A0A3B4DNK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:nup88
gene id: 42514:nup88
uniprot id: A0A3B4CFQ5
names: Subcellular Location Annotation
messages: nuclear pore complex

42514:kdm7ab
gene id: 42514:kdm7ab
uniprot id: A0A3B4DHQ9
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

42514:ribc2
gene id: 42514:ribc2
uniprot id: A0A3B4DNV5
names: Similarity
messages: Belongs to the RIB43A family.

42514:neu1
gene id: 42514:neu1
uniprot id: A0A3B4C1U7
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

42514:adcy2a
gene id: 42514:adcy2a
uniprot id: A0A3B4DS97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

42514:LOC108441491
gene id: 42514:LOC108441491
uniprot id: A0A3B4DMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:msx2a
gene id: 42514:msx2a
uniprot id: A0A3B4DPE5
names: Subcellular Location Annotation
messages: Nucleus

42514:uchl1
gene id: 42514:uchl1
uniprot id: A0A3B4BRZ7
names: Similarity
messages: Belongs to the peptidase C12 family.

42514:adrb2b
gene id: 42514:adrb2b
uniprot id: A0A3B4CKI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:ccnl1a
gene id: 42514:ccnl1a
uniprot id: A0A3B4DZ15
names: Similarity
messages: Belongs to the cyclin family.

42514:gja10a
gene id: 42514:gja10a
uniprot id: A0A3B4BU85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:erap1a
gene id: 42514:erap1a
uniprot id: A0A3B4DT91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

42514:prpf3
gene id: 42514:prpf3
uniprot id: A0A3B4C2K7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

42514:ldlra
gene id: 42514:ldlra
uniprot id: A0A3B4D017
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ruvbl1
gene id: 42514:ruvbl1
uniprot id: A0A3B4CIC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

42514:tjp1b
gene id: 42514:tjp1b
uniprot id: A0A3B4BKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:fermt2
gene id: 42514:fermt2
uniprot id: A0A3B4BR26
uniprot id: A0A3B4BUI1
uniprot id: A0A3B4BUJ8
names: Similarity
messages: Belongs to the kindlin family.

42514:htr1fa
gene id: 42514:htr1fa
uniprot id: A0A3B4E0G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:paqr8
gene id: 42514:paqr8
uniprot id: A0A3B4EQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:masp2
gene id: 42514:masp2
uniprot id: A0A3B4D0Y2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:hdac6
gene id: 42514:hdac6
uniprot id: A0A3B4EGZ0
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

42514:tarbp2
gene id: 42514:tarbp2
uniprot id: A0A3B4C1P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC.

42514:tlx3b
gene id: 42514:tlx3b
uniprot id: A0A3B4DAX4
names: Subcellular Location Annotation
messages: Nucleus

42514:zgc:101566
gene id: 42514:zgc:101566
uniprot id: A0A3B4DQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

42514:dus4l
gene id: 42514:dus4l
uniprot id: A0A3B4ECE8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

42514:mfsd6l
gene id: 42514:mfsd6l
uniprot id: A0A3B4BRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

42514:rgmd
gene id: 42514:rgmd
uniprot id: A0A3B4C6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

42514:adipor2
gene id: 42514:adipor2
uniprot id: A0A3B4EHD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:ldhbb
gene id: 42514:ldhbb
uniprot id: A0A3B4EN28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

42514:plppr2a
gene id: 42514:plppr2a
uniprot id: A0A3B4BTV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:rad17
gene id: 42514:rad17
uniprot id: A0A3B4D1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

42514:pdss1
gene id: 42514:pdss1
uniprot id: A0A3B4EMY4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

42514:appb
gene id: 42514:appb
uniprot id: A0A3B4CPH8
uniprot id: A0A3B4E7I8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Cytoplasm
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Golgi apparatus
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus
messages: Secreted

42514:spdl1
gene id: 42514:spdl1
uniprot id: A0A3B4CJY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spindly family.
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex.
messages: kinetochore

42514:slc13a4
gene id: 42514:slc13a4
uniprot id: A0A3B4EBY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

42514:rrn3
gene id: 42514:rrn3
uniprot id: A0A3B4C8B5
names: Similarity
messages: Belongs to the RRN3 family.

42514:LOC108443054
gene id: 42514:LOC108443054
uniprot id: A0A3B4C722
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:rars1
gene id: 42514:rars1
uniprot id: A0A3B4CM22
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

42514:emc9
gene id: 42514:emc9
uniprot id: A0A3B4C0R7
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

42514:cep63
gene id: 42514:cep63
uniprot id: A0A3B4DCR7
names: Similarity
messages: Belongs to the CEP63 family.

42514:avpr1ab
gene id: 42514:avpr1ab
uniprot id: A0A3B4DPX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:tap2t
gene id: 42514:tap2t
uniprot id: A0A3B4CZ72
names: Subcellular Location Annotation
messages: Membrane

42514:ppp1r13ba
gene id: 42514:ppp1r13ba
uniprot id: A0A3B4BPK4
uniprot id: A0A3B4BSJ1
names: Subcellular Location Annotation
messages: Nucleus

42514:mfsd3
gene id: 42514:mfsd3
uniprot id: A0A3B4BWF8
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108435089
gene id: 42514:LOC108435089
uniprot id: A0A3B4CXM3
names: Subcellular Location Annotation
messages: Membrane

42514:bri3
gene id: 42514:bri3
uniprot id: A0A3B4CKD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

42514:LOC108443123
gene id: 42514:LOC108443123
uniprot id: A0A3B4DRB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:ippk
gene id: 42514:ippk
uniprot id: A0A3B4BS10
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

42514:LOC108425693
gene id: 42514:LOC108425693
uniprot id: A0A3B4DYD5
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108413345
gene id: 42514:LOC108413345
uniprot id: A0A3B4EI06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

42514:inhbb
gene id: 42514:inhbb
uniprot id: A0A3B4CK11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

42514:sike1
gene id: 42514:sike1
uniprot id: A0A3B4CSA3
names: Similarity
messages: Belongs to the SIKE family.

42514:vat1
gene id: 42514:vat1
uniprot id: A0A3B4CCW2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

42514:cul1b
gene id: 42514:cul1b
uniprot id: A0A3B4CMZ8
names: Similarity
messages: Belongs to the cullin family.

42514:zgc:77880
gene id: 42514:zgc:77880
uniprot id: A0A3B4D5X5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:lhx3
gene id: 42514:lhx3
uniprot id: A0A3B4DHI5
names: Subcellular Location Annotation
messages: Nucleus

42514:mms19
gene id: 42514:mms19
uniprot id: A0A3B4C7V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

42514:alx1
gene id: 42514:alx1
uniprot id: A0A3B4CMQ1
names: Subcellular Location Annotation
messages: Nucleus

42514:kif3a
gene id: 42514:kif3a
uniprot id: A0A3B4DPH9
uniprot id: A0A3B4DQL1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:dpagt1
gene id: 42514:dpagt1
uniprot id: A0A3B4C431
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:usp3
gene id: 42514:usp3
uniprot id: A0A3B4CA37
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:kcnh2b
gene id: 42514:kcnh2b
uniprot id: A0A3B4D134
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

42514:nr1h4
gene id: 42514:nr1h4
uniprot id: A0A3B4E7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

42514:ccnj
gene id: 42514:ccnj
uniprot id: A0A3B4C317
names: Similarity
messages: Belongs to the cyclin family.

42514:LOC108427782
gene id: 42514:LOC108427782
uniprot id: A0A3B4D177
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:nkain1
gene id: 42514:nkain1
uniprot id: A0A3B4D6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

42514:tbpl2
gene id: 42514:tbpl2
uniprot id: A0A3B4BT14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

42514:LOC108437045
gene id: 42514:LOC108437045
uniprot id: A0A3B4C3Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

42514:LOC108440215
gene id: 42514:LOC108440215
uniprot id: A0A3B4C5Q6
names: Similarity
messages: Belongs to the globin family.

42514:ccm2
gene id: 42514:ccm2
uniprot id: A0A3B4D742
uniprot id: A0A3B4EIC0
names: Similarity
messages: Belongs to the CCM2 family.

42514:LOC108432697
gene id: 42514:LOC108432697
uniprot id: A0A3B4ERF5
names: Subcellular Location Annotation
messages: Membrane

42514:cep170aa
gene id: 42514:cep170aa
uniprot id: A0A3B4DY55
names: Similarity
messages: Belongs to the CEP170 family.

42514:rcan1a
gene id: 42514:rcan1a
uniprot id: A0A3B4CLY0
uniprot id: A0A3B4E735
names: Similarity
messages: Belongs to the RCAN family.

42514:LOC108433590
gene id: 42514:LOC108433590
uniprot id: A0A3B4CG97
names: Similarity
messages: Belongs to the cornifelin family.

42514:LOC108412190
gene id: 42514:LOC108412190
uniprot id: A0A3B4CSH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:man2a2
gene id: 42514:man2a2
uniprot id: A0A3B4DCT3
uniprot id: A0A3B4EQR4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

42514:mettl11b
gene id: 42514:mettl11b
uniprot id: A0A3B4DDS3
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

42514:cd164
gene id: 42514:cd164
uniprot id: A0A3B4BWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

42514:mtg2
gene id: 42514:mtg2
uniprot id: A0A3B4DW05
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

42514:hspb1
gene id: 42514:hspb1
uniprot id: A0A3B4BXK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

42514:cfap45
gene id: 42514:cfap45
uniprot id: A0A3B4DCY5
uniprot id: A0A3B4EMP7
names: Similarity
messages: Belongs to the CFAP45 family.

42514:panx2
gene id: 42514:panx2
uniprot id: A0A3B4CND9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

42514:pdpr
gene id: 42514:pdpr
uniprot id: A0A3B4ELQ0
names: Similarity
messages: Belongs to the GcvT family.

42514:cpvl
gene id: 42514:cpvl
uniprot id: A0A3B4BT07
names: Similarity
messages: Belongs to the peptidase S10 family.

42514:slc25a42
gene id: 42514:slc25a42
uniprot id: A0A3B4D6T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:gask1a
gene id: 42514:gask1a
uniprot id: A0A3B4CYC4
names: Similarity
messages: Belongs to the GASK family.

42514:polr1h
gene id: 42514:polr1h
uniprot id: A0A3B4EKG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: nucleolus

42514:ppp2r2aa
gene id: 42514:ppp2r2aa
uniprot id: A0A3B4DJX4
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

42514:wdr18
gene id: 42514:wdr18
uniprot id: A0A3B4D676
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Dynein axonemal particle
messages: nucleolus
messages: nucleoplasm

42514:abcd3a
gene id: 42514:abcd3a
uniprot id: A0A3B4EE25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

42514:napaa
gene id: 42514:napaa
uniprot id: A0A3B4CGT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

42514:lta
gene id: 42514:lta
uniprot id: A0A3B4E607
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:psd3l
gene id: 42514:psd3l
uniprot id: A0A3B4EBU6
names: Subcellular Location Annotation
messages: ruffle membrane

42514:dbnlb
gene id: 42514:dbnlb
uniprot id: A0A3B4CY89
uniprot id: A0A3B4CZW2
uniprot id: A0A3B4ECZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Early endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

42514:tmtc3
gene id: 42514:tmtc3
uniprot id: A0A3B4ELG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

42514:LOC108414297
gene id: 42514:LOC108414297
uniprot id: A0A3B4BNP8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:six5
gene id: 42514:six5
uniprot id: A0A3B4CNH4
names: Subcellular Location Annotation
messages: Nucleus

42514:zgc:65811
gene id: 42514:zgc:65811
uniprot id: A0A3B4CDR6
names: Subcellular Location Annotation
messages: Membrane

42514:casc3
gene id: 42514:casc3
uniprot id: A0A3B4CHT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Nucleus speckle
messages: dendrite
messages: perinuclear region

42514:tomm5
gene id: 42514:tomm5
uniprot id: A0A3B4E9W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:scn1bb
gene id: 42514:scn1bb
uniprot id: A0A3B4C0C3
names: Subcellular Location Annotation
messages: Membrane

42514:smad3b
gene id: 42514:smad3b
uniprot id: A0A3B4DZ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:LOC108431307
gene id: 42514:LOC108431307
uniprot id: A0A3B4CDN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

42514:chst1
gene id: 42514:chst1
uniprot id: A0A3B4C1S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

42514:roraa
gene id: 42514:roraa
uniprot id: A0A3B4C898
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:desi2
gene id: 42514:desi2
uniprot id: A0A3B4DVI2
names: Similarity
messages: Belongs to the DeSI family.

42514:stt3a
gene id: 42514:stt3a
uniprot id: A0A3B4DKK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

42514:ak3
gene id: 42514:ak3
uniprot id: A0A3B4E2Y4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

42514:pde6b
gene id: 42514:pde6b
uniprot id: A0A3B4BZ43
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:si:ch211-244b2.4
gene id: 42514:si:ch211-244b2.4
uniprot id: A0A3B4EN03
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:lctla
gene id: 42514:lctla
uniprot id: A0A3B4CBA1
uniprot id: A0A3B4E021
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

42514:hnrnpr
gene id: 42514:hnrnpr
uniprot id: A0A3B4CZ92
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108424633
gene id: 42514:LOC108424633
uniprot id: A0A3B4BPN2
uniprot id: A0A3B4DIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

42514:LOC108412616
gene id: 42514:LOC108412616
uniprot id: A0A3B4BPY7
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

42514:zmp:0000000926
gene id: 42514:zmp:0000000926
uniprot id: A0A3B4C1N1
names: Subcellular Location Annotation
messages: Nucleus

42514:kcnq1.1
gene id: 42514:kcnq1.1
uniprot id: A0A3B4CFY2
uniprot id: A0A3B4E038
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

42514:arl2
gene id: 42514:arl2
uniprot id: A0A3B4CSA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

42514:pknox2
gene id: 42514:pknox2
uniprot id: A0A3B4E7G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

42514:dmrta2
gene id: 42514:dmrta2
uniprot id: A0A3B4CHA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

42514:c6h2orf76
gene id: 42514:c6h2orf76
uniprot id: A0A3B4D3J8
names: Similarity
messages: Belongs to the UPF0538 family.

42514:foxo3b
gene id: 42514:foxo3b
uniprot id: A0A3B4DJX1
names: Subcellular Location Annotation
messages: Nucleus

42514:sh3gl3a
gene id: 42514:sh3gl3a
uniprot id: A0A3B4CH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

42514:mcoln1b
gene id: 42514:mcoln1b
uniprot id: A0A3B4CKF6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

42514:kif20bb
gene id: 42514:kif20bb
uniprot id: A0A3B4DZN9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:ift20
gene id: 42514:ift20
uniprot id: A0A3B4DQI2
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

42514:tmem138
gene id: 42514:tmem138
uniprot id: A0A3B4EKX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

42514:dyrk2
gene id: 42514:dyrk2
uniprot id: A0A3B4DBG8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

42514:stmn2a
gene id: 42514:stmn2a
uniprot id: A0A3B4BYW2
names: Similarity
messages: Belongs to the stathmin family.

42514:fam131a
gene id: 42514:fam131a
uniprot id: A0A3B4CPG1
names: Similarity
messages: Belongs to the FAM131 family.

42514:kifbp
gene id: 42514:kifbp
uniprot id: A0A3B4EHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

42514:hsdl2
gene id: 42514:hsdl2
uniprot id: A0A3B4CHQ8
names: Subcellular Location Annotation
messages: Peroxisome

42514:LOC108419350
gene id: 42514:LOC108419350
uniprot id: A0A3B4E9C2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:npm2b
gene id: 42514:npm2b
uniprot id: A0A3B4BSX6
names: Similarity
messages: Belongs to the nucleoplasmin family.

42514:si:ch73-386h18.1
gene id: 42514:si:ch73-386h18.1
uniprot id: A0A3B4DB27
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108425368
gene id: 42514:LOC108425368
uniprot id: A0A3B4DI55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

42514:rps6kb1b
gene id: 42514:rps6kb1b
uniprot id: A0A3B4EJ18
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

42514:ppfia2
gene id: 42514:ppfia2
uniprot id: A0A3B4C5X8
uniprot id: A0A3B4C6V3
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

42514:ddc
gene id: 42514:ddc
uniprot id: A0A3B4DV82
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

42514:tmem129
gene id: 42514:tmem129
uniprot id: A0A3B4CZH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

42514:vat1l
gene id: 42514:vat1l
uniprot id: A0A3B4E1N9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

42514:timm23b
gene id: 42514:timm23b
uniprot id: A0A3B4C532
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

42514:papola
gene id: 42514:papola
uniprot id: A0A3B4DPL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

42514:emc8
gene id: 42514:emc8
uniprot id: A0A3B4DCY0
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

42514:LOC108424537
gene id: 42514:LOC108424537
uniprot id: A0A3B4BTG9
names: Similarity
messages: Belongs to the FMO family.

42514:ifitm5
gene id: 42514:ifitm5
uniprot id: A0A3B4BVE4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

42514:LOC108434413
gene id: 42514:LOC108434413
uniprot id: A0A3B4EM86
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

42514:rps13
gene id: 42514:rps13
uniprot id: A0A3B4E140
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

42514:syf2
gene id: 42514:syf2
uniprot id: A0A3B4E2K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

42514:clp1
gene id: 42514:clp1
uniprot id: A0A3B4EJE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

42514:esrra
gene id: 42514:esrra
uniprot id: A0A3B4DR14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

42514:LOC108429863
gene id: 42514:LOC108429863
uniprot id: A0A3B4BUX5
uniprot id: A0A3B4DPI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

42514:abcb7
gene id: 42514:abcb7
uniprot id: A0A3B4E8J0
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108411878
gene id: 42514:LOC108411878
uniprot id: A0A3B4DXH8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

42514:eef1akmt1
gene id: 42514:eef1akmt1
uniprot id: A0A3B4C0C9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

42514:sdf4
gene id: 42514:sdf4
uniprot id: A0A3B4CVP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

42514:LOC108442282
gene id: 42514:LOC108442282
uniprot id: A0A3B4EC08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

42514:elavl4
gene id: 42514:elavl4
uniprot id: A0A3B4CJC6
uniprot id: A0A3B4CKR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

42514:myd88
gene id: 42514:myd88
uniprot id: A0A3B4E9G4
names: Function
names: Subcellular Location Annotation
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm

42514:avl9
gene id: 42514:avl9
uniprot id: A0A3B4C0S6
names: Subcellular Location Annotation
messages: Recycling endosome

42514:uts2a
gene id: 42514:uts2a
uniprot id: A0A3B4E9B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

42514:LOC108424859
gene id: 42514:LOC108424859
uniprot id: A0A3B4D9W7
names: Subcellular Location Annotation
messages: Membrane

42514:sema3bl
gene id: 42514:sema3bl
uniprot id: A0A3B4CQU3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:igfbp5a
gene id: 42514:igfbp5a
uniprot id: A0A3B4DK06
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:ptch1
gene id: 42514:ptch1
uniprot id: A0A3B4C2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

42514:slc17a9a
gene id: 42514:slc17a9a
uniprot id: A0A3B4BR68
names: Subcellular Location Annotation
messages: Membrane

42514:cog1
gene id: 42514:cog1
uniprot id: A0A3B4C6Z3
uniprot id: A0A3B4DWA8
names: Similarity
messages: Belongs to the COG1 family.

42514:LOC108435133
gene id: 42514:LOC108435133
uniprot id: A0A3B4CT16
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:cdx1a
gene id: 42514:cdx1a
uniprot id: A0A3B4C0V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

42514:scn8aa
gene id: 42514:scn8aa
uniprot id: A0A3B4D5I6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

42514:cant1b
gene id: 42514:cant1b
uniprot id: A0A3B4EFJ7
names: Similarity
messages: Belongs to the apyrase family.

42514:LOC108411014
gene id: 42514:LOC108411014
uniprot id: A0A3B4D305
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

42514:LOC108442818
gene id: 42514:LOC108442818
uniprot id: A0A3B4D9M1
names: Similarity
messages: Belongs to the cornifelin family.

42514:zar1l
gene id: 42514:zar1l
uniprot id: A0A3B4EBJ1
names: Similarity
messages: Belongs to the ZAR1 family.

42514:ckap2l
gene id: 42514:ckap2l
uniprot id: A0A3B4E9D9
names: Similarity
messages: Belongs to the CKAP2 family.

42514:irf4b
gene id: 42514:irf4b
uniprot id: A0A3B4D374
names: Subcellular Location Annotation
messages: Nucleus

42514:capn5a
gene id: 42514:capn5a
uniprot id: A0A3B4CXJ1
names: Similarity
messages: Belongs to the peptidase C2 family.

42514:LOC108436233
gene id: 42514:LOC108436233
uniprot id: A0A3B4CIR1
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

42514:chst2a
gene id: 42514:chst2a
uniprot id: A0A3B4CIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

42514:si:dkey-120c6.5
gene id: 42514:si:dkey-120c6.5
uniprot id: A0A3B4CF70
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108428970
gene id: 42514:LOC108428970
uniprot id: A0A3B4ECL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

42514:LOC108429630
gene id: 42514:LOC108429630
uniprot id: A0A3B4CF75
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:mturn
gene id: 42514:mturn
uniprot id: A0A3B4CMV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

42514:slc30a6
gene id: 42514:slc30a6
uniprot id: A0A3B4BQW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

42514:adora1b
gene id: 42514:adora1b
uniprot id: A0A3B4BWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

42514:si:dkey-30c15.17
gene id: 42514:si:dkey-30c15.17
uniprot id: A0A3B4EIS7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

42514:rfc4
gene id: 42514:rfc4
uniprot id: A0A3B4DW66
names: Similarity
messages: Belongs to the activator 1 small subunits family.

42514:slc6a14
gene id: 42514:slc6a14
uniprot id: A0A3B4C0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:unc119b
gene id: 42514:unc119b
uniprot id: A0A3B4CBB9
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

42514:med20
gene id: 42514:med20
uniprot id: A0A3B4BWQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:rab21
gene id: 42514:rab21
uniprot id: A0A3B4CWL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: trans-Golgi network

42514:keap1a
gene id: 42514:keap1a
uniprot id: A0A3B4EJF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

42514:clgn
gene id: 42514:clgn
uniprot id: A0A3B4CCN5
names: Similarity
messages: Belongs to the calreticulin family.

42514:si:dkey-3h3.3
gene id: 42514:si:dkey-3h3.3
uniprot id: A0A3B4EG25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

42514:ctnnb1
gene id: 42514:ctnnb1
uniprot id: A0A3B4CUD5
uniprot id: A0A3B4EAA1
uniprot id: A0A3B4EAM0
names: Similarity
messages: Belongs to the beta-catenin family.

42514:LOC108425184
gene id: 42514:LOC108425184
uniprot id: A0A3B4CHG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

42514:serpina10a
gene id: 42514:serpina10a
uniprot id: A0A3B4DPM2
names: Similarity
messages: Belongs to the serpin family.

42514:cmpk
gene id: 42514:cmpk
uniprot id: A0A3B4E453
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

42514:LOC108443081
gene id: 42514:LOC108443081
uniprot id: A0A3B4C9D2
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:plod2
gene id: 42514:plod2
uniprot id: A0A3B4DGG2
uniprot id: A0A3B4EPM0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

42514:l3mbtl1b
gene id: 42514:l3mbtl1b
uniprot id: A0A3B4D872
names: Subcellular Location Annotation
messages: Nucleus

42514:pvalb3
gene id: 42514:pvalb3
uniprot id: A0A3B4DP32
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

42514:LOC108430459
gene id: 42514:LOC108430459
uniprot id: A0A3B4DD72
names: Similarity
messages: Belongs to the CRK family.

42514:LOC108427455
gene id: 42514:LOC108427455
uniprot id: A0A3B4CFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

42514:slc37a2
gene id: 42514:slc37a2
uniprot id: A0A3B4CCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

42514:tsg101a
gene id: 42514:tsg101a
uniprot id: A0A3B4DZK0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

42514:fam83fa
gene id: 42514:fam83fa
uniprot id: A0A3B4EJ33
names: Similarity
messages: Belongs to the FAM83 family.

42514:ssh2a
gene id: 42514:ssh2a
uniprot id: A0A3B4BW73
uniprot id: A0A3B4BW94
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

42514:serpine1
gene id: 42514:serpine1
uniprot id: A0A3B4D8M5
names: Similarity
messages: Belongs to the serpin family.

42514:dpm2
gene id: 42514:dpm2
uniprot id: A0A3B4DWZ0
uniprot id: A0A3B4DX42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

42514:rbm10
gene id: 42514:rbm10
uniprot id: A0A3B4BYK5
names: Subcellular Location Annotation
messages: Nucleus

42514:myo1f
gene id: 42514:myo1f
uniprot id: A0A3B4ENL8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:LOC108436859
gene id: 42514:LOC108436859
uniprot id: A0A3B4E3R3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:pex5lb
gene id: 42514:pex5lb
uniprot id: A0A3B4C0X2
uniprot id: A0A3B4C4F0
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

42514:dipk1ab
gene id: 42514:dipk1ab
uniprot id: A0A3B4DA41
names: Similarity
messages: Belongs to the DIPK family.

42514:si:rp71-17i16.5
gene id: 42514:si:rp71-17i16.5
uniprot id: A0A3B4D533
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

42514:vgll3
gene id: 42514:vgll3
uniprot id: A0A3B4E403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

42514:spire1a
gene id: 42514:spire1a
uniprot id: A0A3B4C4P0
uniprot id: A0A3B4DPW2
uniprot id: A0A3B4DQG9
uniprot id: A0A3B4DSG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

42514:tpra1
gene id: 42514:tpra1
uniprot id: A0A3B4ERN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

42514:si:dkey-7j14.6
gene id: 42514:si:dkey-7j14.6
uniprot id: A0A3B4DKV9
names: Similarity
messages: Belongs to the MS4A family.

42514:LOC108435612
gene id: 42514:LOC108435612
uniprot id: A0A3B4D107
names: Subcellular Location Annotation
messages: Membrane

42514:paqr5a
gene id: 42514:paqr5a
uniprot id: A0A3B4CAW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:rtca
gene id: 42514:rtca
uniprot id: A0A3B4CXU9
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

42514:smim15
gene id: 42514:smim15
uniprot id: A0A3B4CFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

42514:gcdhb
gene id: 42514:gcdhb
uniprot id: A0A3B4BT41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

42514:zmp:0000001062
gene id: 42514:zmp:0000001062
uniprot id: A0A3B4E5G3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:foxr1
gene id: 42514:foxr1
uniprot id: A0A3B4CH87
names: Subcellular Location Annotation
messages: Nucleus

42514:tyr
gene id: 42514:tyr
uniprot id: A0A3B4D9D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

42514:ptp4a2b
gene id: 42514:ptp4a2b
uniprot id: A0A3B4DNC0
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

42514:mcm3
gene id: 42514:mcm3
uniprot id: A0A3B4ENS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

42514:nectin3b
gene id: 42514:nectin3b
uniprot id: A0A3B4E3C6
names: Similarity
messages: Belongs to the nectin family.

42514:nampt2
gene id: 42514:nampt2
uniprot id: A0A3B4CDC6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

42514:zmp:0000000521
gene id: 42514:zmp:0000000521
uniprot id: A0A3B4CB38
names: Similarity
messages: Belongs to the SPIN/STSY family.

42514:LOC108441169
gene id: 42514:LOC108441169
uniprot id: A0A3B4CXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

42514:arf3a
gene id: 42514:arf3a
uniprot id: A0A3B4D532
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

42514:si:busm1-52i16.2
gene id: 42514:si:busm1-52i16.2
uniprot id: A0A3B4C0U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:tbx2b
gene id: 42514:tbx2b
uniprot id: A0A3B4BT18
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:ntn2
gene id: 42514:ntn2
uniprot id: A0A3B4E740
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:kcnt1
gene id: 42514:kcnt1
uniprot id: A0A3B4CLC5
uniprot id: A0A3B4E6C1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:memo1
gene id: 42514:memo1
uniprot id: A0A3B4BNH6
names: Similarity
messages: Belongs to the MEMO1 family.

42514:ppp2r2cb
gene id: 42514:ppp2r2cb
uniprot id: A0A3B4D731
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

42514:prph2la
gene id: 42514:prph2la
uniprot id: A0A3B4DND2
names: Subcellular Location Annotation
messages: Membrane

42514:pank4
gene id: 42514:pank4
uniprot id: A0A3B4D781
names: Similarity
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

42514:klhl40a
gene id: 42514:klhl40a
uniprot id: A0A3B4EM04
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

42514:yars1
gene id: 42514:yars1
uniprot id: A0A3B4BXE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

42514:gcnt4a
gene id: 42514:gcnt4a
uniprot id: A0A3B4DE67
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

42514:scocb
gene id: 42514:scocb
uniprot id: A0A3B4ELN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

42514:camsap1b
gene id: 42514:camsap1b
uniprot id: A0A3B4DE03
uniprot id: A0A3B4EQA2
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

42514:LOC108410695
gene id: 42514:LOC108410695
uniprot id: A0A3B4E1T7
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

42514:zwilch
gene id: 42514:zwilch
uniprot id: A0A3B4DZB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

42514:LOC108436083
gene id: 42514:LOC108436083
uniprot id: A0A3B4EKW3
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

42514:LOC108412053
gene id: 42514:LOC108412053
uniprot id: A0A3B4DAR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:LOC108435090
gene id: 42514:LOC108435090
uniprot id: A0A3B4CXD1
uniprot id: A0A3B4CY40
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

42514:cxxc1a
gene id: 42514:cxxc1a
uniprot id: A0A3B4EIE5
names: Subcellular Location Annotation
messages: Nucleus

42514:cacng5b
gene id: 42514:cacng5b
uniprot id: A0A3B4DFP9
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

42514:LOC108437829
gene id: 42514:LOC108437829
uniprot id: A0A3B4CVB5
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

42514:LOC108427100
gene id: 42514:LOC108427100
uniprot id: A0A3B4ELZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

42514:fabp10a
gene id: 42514:fabp10a
uniprot id: A0A3B4DK73
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:tyro3
gene id: 42514:tyro3
uniprot id: A0A3B4BTB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

42514:LOC108413265
gene id: 42514:LOC108413265
uniprot id: A0A3B4EP29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

42514:rab3da
gene id: 42514:rab3da
uniprot id: A0A3B4C0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

42514:atf7a
gene id: 42514:atf7a
uniprot id: A0A3B4EIS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

42514:arhgef7b
gene id: 42514:arhgef7b
uniprot id: A0A3B4D3Z1
uniprot id: A0A3B4EH92
names: Subcellular Location Annotation
messages: lamellipodium

42514:ebna1bp2
gene id: 42514:ebna1bp2
uniprot id: A0A3B4E4Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

42514:LOC108439237
gene id: 42514:LOC108439237
uniprot id: A0A3B4C0Z2
names: Subcellular Location Annotation
messages: Membrane

42514:tmem86b
gene id: 42514:tmem86b
uniprot id: A0A3B4C186
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

42514:cert1a
gene id: 42514:cert1a
uniprot id: A0A3B4DCE4
uniprot id: A0A3B4DCF8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

42514:hagh
gene id: 42514:hagh
uniprot id: A0A3B4D6Y5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

42514:rtf2
gene id: 42514:rtf2
uniprot id: A0A3B4E1K9
names: Similarity
messages: Belongs to the rtf2 family.

42514:six6b
gene id: 42514:six6b
uniprot id: A0A3B4DDP2
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108426109
gene id: 42514:LOC108426109
uniprot id: A0A3B4E0W2
names: Subcellular Location Annotation
messages: Nucleus

42514:mief1
gene id: 42514:mief1
uniprot id: A0A3B4CLR3
uniprot id: A0A3B4CNM1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

42514:psme1
gene id: 42514:psme1
uniprot id: A0A3B4EJ40
names: Similarity
messages: Belongs to the PA28 family.

42514:adgrv1
gene id: 42514:adgrv1
uniprot id: A0A3B4DW60
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108444553
gene id: 42514:LOC108444553
uniprot id: A0A3B4EKH3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:LOC108424756
gene id: 42514:LOC108424756
uniprot id: A0A3B4DGE7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108425189
gene id: 42514:LOC108425189
uniprot id: A0A3B4CG52
uniprot id: A0A3B4E011
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:LOC108425091
gene id: 42514:LOC108425091
uniprot id: A0A3B4CN09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

42514:LOC108429324
gene id: 42514:LOC108429324
uniprot id: A0A3B4DD83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dhrs13l1
gene id: 42514:dhrs13l1
uniprot id: A0A3B4EF25
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:psmg1
gene id: 42514:psmg1
uniprot id: A0A3B4E5D5
names: Similarity
messages: Belongs to the PSMG1 family.

42514:slc8a2b
gene id: 42514:slc8a2b
uniprot id: A0A3B4EEE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

42514:sf1
gene id: 42514:sf1
uniprot id: A0A3B4DX43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

42514:wnt9a
gene id: 42514:wnt9a
uniprot id: A0A3B4C291
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:crygmxl2
gene id: 42514:crygmxl2
uniprot id: A0A3B4EM18
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:bola3
gene id: 42514:bola3
uniprot id: A0A3B4CCQ8
names: Similarity
messages: Belongs to the BolA/IbaG family.

42514:atp10d
gene id: 42514:atp10d
uniprot id: A0A3B4DXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

42514:tspan18b
gene id: 42514:tspan18b
uniprot id: A0A3B4CS25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:nop53
gene id: 42514:nop53
uniprot id: A0A3B4DVL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

42514:hrh3
gene id: 42514:hrh3
uniprot id: A0A3B4DZE6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:sgsm1b
gene id: 42514:sgsm1b
uniprot id: A0A3B4CQ73
names: Similarity
messages: Belongs to the RUTBC family.

42514:suox
gene id: 42514:suox
uniprot id: A0A3B4BUQ2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.
messages: Mitochondrion intermembrane space

42514:galnt11
gene id: 42514:galnt11
uniprot id: A0A3B4DFN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:st14a
gene id: 42514:st14a
uniprot id: A0A3B4C7S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:tenm4
gene id: 42514:tenm4
uniprot id: A0A3B4C179
uniprot id: A0A3B4DRU1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108440860
gene id: 42514:LOC108440860
uniprot id: A0A3B4C281
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:cactin
gene id: 42514:cactin
uniprot id: A0A3B4C4I6
names: Similarity
messages: Belongs to the CACTIN family.

42514:panx3
gene id: 42514:panx3
uniprot id: A0A3B4CPT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

42514:pld3
gene id: 42514:pld3
uniprot id: A0A3B4DYK9
names: Similarity
messages: Belongs to the phospholipase D family.

42514:grpr
gene id: 42514:grpr
uniprot id: A0A3B4DWN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:gsk3aa
gene id: 42514:gsk3aa
uniprot id: A0A3B4BYG5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

42514:dgkh
gene id: 42514:dgkh
uniprot id: A0A3B4E4I2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

42514:b4galt1l
gene id: 42514:b4galt1l
uniprot id: A0A3B4DT58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

42514:alg14
gene id: 42514:alg14
uniprot id: A0A3B4CXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

42514:acsm3
gene id: 42514:acsm3
uniprot id: A0A3B4ECK2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:cbl
gene id: 42514:cbl
uniprot id: A0A3B4EIV4
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

42514:LOC108412772
gene id: 42514:LOC108412772
uniprot id: A0A3B4CXH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

42514:otub1b
gene id: 42514:otub1b
uniprot id: A0A3B4CSU4
names: Similarity
messages: Belongs to the peptidase C65 family.

42514:LOC108441277
gene id: 42514:LOC108441277
uniprot id: A0A3B4CJS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

42514:gcnt7
gene id: 42514:gcnt7
uniprot id: A0A3B4E1K1
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

42514:htra1a
gene id: 42514:htra1a
uniprot id: A0A3B4DA78
names: Similarity
messages: Belongs to the peptidase S1C family.

42514:kdm7aa
gene id: 42514:kdm7aa
uniprot id: A0A3B4DPD9
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

42514:luc7l3
gene id: 42514:luc7l3
uniprot id: A0A3B4EEZ4
names: Similarity
messages: Belongs to the Luc7 family.

42514:irgq1
gene id: 42514:irgq1
uniprot id: A0A3B4EH77
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

42514:cart2
gene id: 42514:cart2
uniprot id: A0A158V3X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

42514:LOC108437939
gene id: 42514:LOC108437939
uniprot id: A0A3B4CHG1
names: Similarity
messages: Belongs to the aldo/keto reductase family.

42514:lipg
gene id: 42514:lipg
uniprot id: A0A3B4CZ23
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:acp5a
gene id: 42514:acp5a
uniprot id: A0A3B4DMI1
names: Cofactor
messages: Binds 2 iron ions per subunit.

42514:LOC108429917
gene id: 42514:LOC108429917
uniprot id: A0A3B4D5D8
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

42514:asip2b
gene id: 42514:asip2b
uniprot id: A0A3B4CLA6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:grk6
gene id: 42514:grk6
uniprot id: A0A3B4CJ72
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

42514:gdf3
gene id: 42514:gdf3
uniprot id: A0A3B4BP05
names: Similarity
messages: Belongs to the TGF-beta family.

42514:tfap2a
gene id: 42514:tfap2a
uniprot id: A0A3B4D6G5
uniprot id: A0A3B4EIC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

42514:LOC108437265
gene id: 42514:LOC108437265
uniprot id: A0A3B4D1V4
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108438422
gene id: 42514:LOC108438422
uniprot id: A0A3B4CYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:LOC108424618
gene id: 42514:LOC108424618
uniprot id: A0A3B4BMD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:mrps2
gene id: 42514:mrps2
uniprot id: A0A3B4DCM7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

42514:camk2g1
gene id: 42514:camk2g1
uniprot id: A0A3B4CY27
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

42514:lim2.3
gene id: 42514:lim2.3
uniprot id: A0A3B4C7C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

42514:LOC108443079
gene id: 42514:LOC108443079
uniprot id: A0A3B4C6Z8
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:acte1
gene id: 42514:acte1
uniprot id: A0A3B4C5P3
names: Similarity
messages: Belongs to the actin family.

42514:b3gnt7
gene id: 42514:b3gnt7
uniprot id: A0A3B4CNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:ddah1
gene id: 42514:ddah1
uniprot id: A0A3B4BTI8
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

42514:prpf19
gene id: 42514:prpf19
uniprot id: A0A3B4CS95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

42514:hoxc11b
gene id: 42514:hoxc11b
uniprot id: A0A3B4BQ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:edem3
gene id: 42514:edem3
uniprot id: A0A3B4D446
uniprot id: A0A3B4D5X4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

42514:pigw
gene id: 42514:pigw
uniprot id: A0A3B4BUK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

42514:efna3a
gene id: 42514:efna3a
uniprot id: A0A3B4E5Y3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:myo7aa
gene id: 42514:myo7aa
uniprot id: A0A3B4CNH3
uniprot id: A0A3B4E6A8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:LOC108440754
gene id: 42514:LOC108440754
uniprot id: A0A3B4DY38
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:impdh1a
gene id: 42514:impdh1a
uniprot id: A0A3B4D0T5
uniprot id: A0A3B4EDV1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

42514:nrp2a
gene id: 42514:nrp2a
uniprot id: A0A3B4DNR6
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:csgalnact1a
gene id: 42514:csgalnact1a
uniprot id: A0A3B4BV55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

42514:six4b
gene id: 42514:six4b
uniprot id: A0A3B4DDA3
names: Subcellular Location Annotation
messages: Nucleus

42514:slc6a18
gene id: 42514:slc6a18
uniprot id: A0A3B4DAM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:LOC108436432
gene id: 42514:LOC108436432
uniprot id: A0A3B4DSJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

42514:ctnna1
gene id: 42514:ctnna1
uniprot id: A0A3B4CNC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

42514:slco1c1
gene id: 42514:slco1c1
uniprot id: A0A3B4CZF0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:itga3a
gene id: 42514:itga3a
uniprot id: A0A3B4DMU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

42514:pias1b
gene id: 42514:pias1b
uniprot id: A0A3B4DYR6
names: Similarity
messages: Belongs to the PIAS family.

42514:fam166b
gene id: 42514:fam166b
uniprot id: A0A3B4CYE8
names: Similarity
messages: Belongs to the CIMIP2 family.

42514:gabrr3a
gene id: 42514:gabrr3a
uniprot id: A0A3B4DZM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:LOC108435978
gene id: 42514:LOC108435978
uniprot id: A0A3B4C076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:LOC108433071
gene id: 42514:LOC108433071
uniprot id: A0A3B4C3G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:arpc1a
gene id: 42514:arpc1a
uniprot id: A0A3B4ECT5
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

42514:adss1
gene id: 42514:adss1
uniprot id: A0A3B4CTF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

42514:pola2
gene id: 42514:pola2
uniprot id: A0A3B4CPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

42514:ppm1nb
gene id: 42514:ppm1nb
uniprot id: A0A3B4CII1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

42514:rgs9b
gene id: 42514:rgs9b
uniprot id: A0A3B4DUF1
names: Subcellular Location Annotation
messages: Membrane

42514:fam49al
gene id: 42514:fam49al
uniprot id: A0A3B4BWV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

42514:endou
gene id: 42514:endou
uniprot id: A0A3B4DZQ8
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

42514:zgc:110782
gene id: 42514:zgc:110782
uniprot id: A0A3B4C592
names: Similarity
messages: Belongs to the aldo/keto reductase family.

42514:rptor
gene id: 42514:rptor
uniprot id: A0A3B4D9T2
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

42514:gpr186
gene id: 42514:gpr186
uniprot id: A0A3B4D9M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:LOC108434245
gene id: 42514:LOC108434245
uniprot id: A0A3B4DP03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

42514:ormdl3
gene id: 42514:ormdl3
uniprot id: A0A3B4BXZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

42514:foxm1
gene id: 42514:foxm1
uniprot id: A0A3B4EE59
names: Subcellular Location Annotation
messages: Nucleus

42514:tp53rk
gene id: 42514:tp53rk
uniprot id: A0A3B4BN53
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

42514:LOC108432818
gene id: 42514:LOC108432818
uniprot id: A0A3B4ECA3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108412459
gene id: 42514:LOC108412459
uniprot id: A0A3B4BZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

42514:cers5
gene id: 42514:cers5
uniprot id: A0A3B4D068
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

42514:gstz1
gene id: 42514:gstz1
uniprot id: A0A3B4CJ18
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

42514:LOC108428935
gene id: 42514:LOC108428935
uniprot id: A0A3B4CT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

42514:atl1
gene id: 42514:atl1
uniprot id: A0A3B4C6M1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

42514:rab5if
gene id: 42514:rab5if
uniprot id: A0A3B4EGC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:f7l
gene id: 42514:f7l
uniprot id: A0A3B4DT30
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:tmem19
gene id: 42514:tmem19
uniprot id: A0A3B4EEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

42514:LOC108414120
gene id: 42514:LOC108414120
uniprot id: A0A3B4DH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

42514:mark4
gene id: 42514:mark4
uniprot id: A0A3B4BZZ3
uniprot id: A0A3B4DQW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

42514:gabra4
gene id: 42514:gabra4
uniprot id: A0A3B4D3A7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:hs3st4
gene id: 42514:hs3st4
uniprot id: A0A3B4C0T8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:st6gal2b
gene id: 42514:st6gal2b
uniprot id: A0A3B4BWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:si:ch211-171h4.3
gene id: 42514:si:ch211-171h4.3
uniprot id: A0A3B4DCM1
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:acads
gene id: 42514:acads
uniprot id: A0A3B4DMY4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

42514:tecrb
gene id: 42514:tecrb
uniprot id: A0A3B4D688
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:tfap2e
gene id: 42514:tfap2e
uniprot id: A0A3B4D0F2
uniprot id: A0A3B4D3W6
names: Similarity
messages: Belongs to the AP-2 family.

42514:rhbdf1a
gene id: 42514:rhbdf1a
uniprot id: A0A3B4C5P2
uniprot id: A0A3B4DV04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

42514:zgc:162160
gene id: 42514:zgc:162160
uniprot id: A0A3B4EAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:pdia2
gene id: 42514:pdia2
uniprot id: A0A3B4DUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

42514:gpc6b
gene id: 42514:gpc6b
uniprot id: A0A3B4D7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

42514:tle2c
gene id: 42514:tle2c
uniprot id: A0A3B4EGN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

42514:si:ch1073-513e17.1
gene id: 42514:si:ch1073-513e17.1
uniprot id: A0A3B4EJ00
names: Subcellular Location Annotation
messages: Membrane

42514:txnipa
gene id: 42514:txnipa
uniprot id: A0A3B4DFP2
names: Similarity
messages: Belongs to the arrestin family.

42514:hmbox1b
gene id: 42514:hmbox1b
uniprot id: A0A3B4C054
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108426860
gene id: 42514:LOC108426860
uniprot id: A0A3B4C658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

42514:rc3h1b
gene id: 42514:rc3h1b
uniprot id: A0A3B4E469
names: Subcellular Location Annotation
messages: P-body

42514:eif1ad
gene id: 42514:eif1ad
uniprot id: A0A3B4DKQ3
names: Similarity
messages: Belongs to the EIF1AD family.

42514:edem2
gene id: 42514:edem2
uniprot id: A0A3B4E1E1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

42514:ybey
gene id: 42514:ybey
uniprot id: A0A3B4DWQ4
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

42514:plk2a
gene id: 42514:plk2a
uniprot id: A0A3B4CEA5
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

42514:gjd2b
gene id: 42514:gjd2b
uniprot id: A0A3B4BNL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:ghrh
gene id: 42514:ghrh
uniprot id: A0A3B4DY85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

42514:etnppl
gene id: 42514:etnppl
uniprot id: A0A3B4CLQ1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

42514:ssbp3a
gene id: 42514:ssbp3a
uniprot id: A0A3B4EKL8
uniprot id: A0A3B4EKM0
names: Subcellular Location Annotation
messages: Nucleus

42514:slc25a46
gene id: 42514:slc25a46
uniprot id: A0A3B4BL68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:antxr2b
gene id: 42514:antxr2b
uniprot id: A0A3B4CML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

42514:s1pr4
gene id: 42514:s1pr4
uniprot id: A0A3B4C025
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:nrn1b
gene id: 42514:nrn1b
uniprot id: A0A3B4E279
names: Similarity
messages: Belongs to the neuritin family.

42514:si:ch211-236h17.3
gene id: 42514:si:ch211-236h17.3
uniprot id: A0A3B4DFF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:nppb
gene id: 42514:nppb
uniprot id: A0A3B4EJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

42514:rpap2
gene id: 42514:rpap2
uniprot id: A0A3B4EKA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

42514:gpx8
gene id: 42514:gpx8
uniprot id: A0A3B4CTK9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

42514:fam151a
gene id: 42514:fam151a
uniprot id: A0A3B4DAG1
names: Similarity
messages: Belongs to the FAM151 family.

42514:tph1b
gene id: 42514:tph1b
uniprot id: A0A3B4E155
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

42514:ano5a
gene id: 42514:ano5a
uniprot id: A0A3B4BQ79
uniprot id: A0A3B4BQG1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:hpse2
gene id: 42514:hpse2
uniprot id: A0A3B4ERS3
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

42514:kif16ba
gene id: 42514:kif16ba
uniprot id: A0A3B4CD86
uniprot id: A0A3B4CFM1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:anxa3b
gene id: 42514:anxa3b
uniprot id: A0A3B4CN59
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

42514:gtf2f2a
gene id: 42514:gtf2f2a
uniprot id: A0A3B4EEA9
uniprot id: A0A3B4EEB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

42514:tgfb5
gene id: 42514:tgfb5
uniprot id: A0A3B4ELT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

42514:nxph2b
gene id: 42514:nxph2b
uniprot id: A0A3B4CB79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

42514:pomca
gene id: 42514:pomca
uniprot id: A0A3B4D7W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

42514:ackr3b
gene id: 42514:ackr3b
uniprot id: A0A3B4BW51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:shox2
gene id: 42514:shox2
uniprot id: A0A3B4DLH9
uniprot id: A0A3B4DLI4
names: Subcellular Location Annotation
messages: Nucleus

42514:smad1
gene id: 42514:smad1
uniprot id: A0A3B4CLW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:LOC108426414
gene id: 42514:LOC108426414
uniprot id: A0A3B4DK71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

42514:LOC108428042
gene id: 42514:LOC108428042
uniprot id: A0A3B4C6S6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:rdh5
gene id: 42514:rdh5
uniprot id: A0A3B4EPU4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:hoxa11b
gene id: 42514:hoxa11b
uniprot id: A0A3B4DNF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:LOC108431496
gene id: 42514:LOC108431496
uniprot id: A0A3B4BQJ2
names: Similarity
messages: Belongs to the cytochrome b5 family.

42514:ska3
gene id: 42514:ska3
uniprot id: A0A3B4BXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

42514:cax2
gene id: 42514:cax2
uniprot id: A0A3B4E5G6
names: Subcellular Location Annotation
messages: Membrane

42514:polg
gene id: 42514:polg
uniprot id: A0A3B4DEP7
uniprot id: A0A3B4ENV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-A family.
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

42514:eif2d
gene id: 42514:eif2d
uniprot id: A0A3B4BP43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF2D family.
messages: Cytoplasm
messages: Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.

42514:LOC108439068
gene id: 42514:LOC108439068
uniprot id: A0A3B4CKI5
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

42514:nudt18
gene id: 42514:nudt18
uniprot id: A0A3B4C9P6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

42514:aurka
gene id: 42514:aurka
uniprot id: A0A3B4CYB1
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

42514:mrpl23
gene id: 42514:mrpl23
uniprot id: A0A3B4BZQ9
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

42514:LOC108439020
gene id: 42514:LOC108439020
uniprot id: A0A3B4CLA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

42514:kdm5ba
gene id: 42514:kdm5ba
uniprot id: A0A3B4E1W0
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

42514:LOC108428864
gene id: 42514:LOC108428864
uniprot id: A0A3B4DCW2
names: Subcellular Location Annotation
messages: Membrane

42514:mterf2
gene id: 42514:mterf2
uniprot id: A0A3B4CSC4
names: Similarity
messages: Belongs to the mTERF family.

42514:edil3b
gene id: 42514:edil3b
uniprot id: A0A3B4BUX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:foxh1
gene id: 42514:foxh1
uniprot id: A0A3B4DUF7
names: Subcellular Location Annotation
messages: Nucleus

42514:fam20cl
gene id: 42514:fam20cl
uniprot id: A0A3B4DBV5
names: Similarity
messages: Belongs to the FAM20 family.

42514:fam91a1
gene id: 42514:fam91a1
uniprot id: A0A3B4DQ96
names: Similarity
messages: Belongs to the FAM91 family.

42514:LOC108411656
gene id: 42514:LOC108411656
uniprot id: A0A3B4CT12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:nmt1a
gene id: 42514:nmt1a
uniprot id: A0A3B4DKX9
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

42514:LOC108410933
gene id: 42514:LOC108410933
uniprot id: A0A3B4ELI6
names: Subcellular Location Annotation
messages: Nucleus

42514:grin3a
gene id: 42514:grin3a
uniprot id: A0A3B4E4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:ripor2
gene id: 42514:ripor2
uniprot id: A0A3B4DLB5
names: Similarity
messages: Belongs to the RIPOR family.

42514:wdfy2
gene id: 42514:wdfy2
uniprot id: A0A3B4DJ15
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

42514:LOC108427746
gene id: 42514:LOC108427746
uniprot id: A0A3B4ECN8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

42514:zgc:153993
gene id: 42514:zgc:153993
uniprot id: A0A3B4E9M6
names: Similarity
messages: Belongs to the Bcl-2 family.

42514:camlg
gene id: 42514:camlg
uniprot id: A0A3B4C0M5
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

42514:LOC108443209
gene id: 42514:LOC108443209
uniprot id: A0A3B4BQD3
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

42514:fahd2a
gene id: 42514:fahd2a
uniprot id: A0A3B4E438
names: Similarity
messages: Belongs to the FAH family.

42514:pin4
gene id: 42514:pin4
uniprot id: A0A3B4EJX5
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

42514:hnrpkl
gene id: 42514:hnrpkl
uniprot id: A0A3B4BLR8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm

42514:thbs4a
gene id: 42514:thbs4a
uniprot id: A0A3B4DEK1
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:zgc:162730
gene id: 42514:zgc:162730
uniprot id: A0A3B4EBV9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

42514:abi2b
gene id: 42514:abi2b
uniprot id: A0A3B4CM39
uniprot id: A0A3B4CP19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

42514:gfra1b
gene id: 42514:gfra1b
uniprot id: A0A3B4DGI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

42514:f8
gene id: 42514:f8
uniprot id: A0A3B4D0Q0
names: Similarity
messages: Belongs to the multicopper oxidase family.

42514:htr2b
gene id: 42514:htr2b
uniprot id: A0A3B4DP99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

42514:g6pc3
gene id: 42514:g6pc3
uniprot id: A0A3B4EM66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

42514:tmem234
gene id: 42514:tmem234
uniprot id: A0A3B4CBT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

42514:snrpb
gene id: 42514:snrpb
uniprot id: A0A3B4CGS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

42514:kcnj19b
gene id: 42514:kcnj19b
uniprot id: A0A3B4D479
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

42514:cdc26
gene id: 42514:cdc26
uniprot id: A0A3B4BS85
names: Similarity
messages: Belongs to the CDC26 family.

42514:aig1
gene id: 42514:aig1
uniprot id: A0A3B4D8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

42514:ddx41
gene id: 42514:ddx41
uniprot id: A0A3B4DU66
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

42514:vps4b
gene id: 42514:vps4b
uniprot id: A0A3B4E2K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

42514:abcc5
gene id: 42514:abcc5
uniprot id: A0A3B4EAT7
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108429433
gene id: 42514:LOC108429433
uniprot id: A0A3B4D7U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:LOC108413310
gene id: 42514:LOC108413310
uniprot id: A0A3B4EMX8
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:lim2.2
gene id: 42514:lim2.2
uniprot id: A0A3B4EEQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

42514:s1pr5a
gene id: 42514:s1pr5a
uniprot id: A0A3B4EGW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:arl3l2
gene id: 42514:arl3l2
uniprot id: A0A3B4BYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

42514:hk2
gene id: 42514:hk2
uniprot id: A0A3B4BRD0
names: Similarity
messages: Belongs to the hexokinase family.

42514:gart
gene id: 42514:gart
uniprot id: A0A3B4DL99
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

42514:th2
gene id: 42514:th2
uniprot id: A0A3B4CEE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

42514:ndufs4
gene id: 42514:ndufs4
uniprot id: A0A3B4D7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

42514:syt1a
gene id: 42514:syt1a
uniprot id: A0A3B4DW00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

42514:fli1
gene id: 42514:fli1
uniprot id: A0A3B4C5Z2
uniprot id: A0A3B4C7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:gna12a
gene id: 42514:gna12a
uniprot id: A0A3B4CW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

42514:eps8l2
gene id: 42514:eps8l2
uniprot id: A0A3B4DFX7
uniprot id: A0A3B4EMP5
names: Similarity
messages: Belongs to the EPS8 family.

42514:il17rd
gene id: 42514:il17rd
uniprot id: A0A3B4EM11
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108440363
gene id: 42514:LOC108440363
uniprot id: A0A3B4BRW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:LOC108435646
gene id: 42514:LOC108435646
uniprot id: A0A3B4CY06
names: Similarity
messages: Belongs to the CARF family.

42514:LOC108417048
gene id: 42514:LOC108417048
uniprot id: A0A3B4DDF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:igflr1
gene id: 42514:igflr1
uniprot id: A0A3B4C9S1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:meis2a
gene id: 42514:meis2a
uniprot id: A0A3B4BRS6
uniprot id: A0A3B4DIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

42514:LOC108431146
gene id: 42514:LOC108431146
uniprot id: A0A3B4E6U2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:tle3a
gene id: 42514:tle3a
uniprot id: A0A3B4C9G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

42514:prkg1b
gene id: 42514:prkg1b
uniprot id: A0A3B4BQF6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

42514:gata2b
gene id: 42514:gata2b
uniprot id: A0A3B4CJM9
names: Subcellular Location Annotation
messages: Nucleus

42514:zpr1
gene id: 42514:zpr1
uniprot id: A0A3B4DJI7
names: Similarity
messages: Belongs to the ZPR1 family.

42514:ccnb3
gene id: 42514:ccnb3
uniprot id: A0A3B4D759
uniprot id: A0A3B4D830
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

42514:srrd
gene id: 42514:srrd
uniprot id: A0A3B4BQJ6
names: Similarity
messages: Belongs to the SRR1 family.

42514:camk1ga
gene id: 42514:camk1ga
uniprot id: A0A3B4BP36
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:napbb
gene id: 42514:napbb
uniprot id: A0A3B4E4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

42514:polr3h
gene id: 42514:polr3h
uniprot id: A0A3B4C956
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

42514:mindy3
gene id: 42514:mindy3
uniprot id: A0A3B4BV65
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

42514:ccm2l
gene id: 42514:ccm2l
uniprot id: A0A3B4E3G6
names: Similarity
messages: Belongs to the CCM2 family.

42514:trpc7a
gene id: 42514:trpc7a
uniprot id: A0A3B4CUC1
names: Subcellular Location Annotation
messages: Membrane

42514:prkd1
gene id: 42514:prkd1
uniprot id: A0A3B4CQW8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

42514:ndufa12
gene id: 42514:ndufa12
uniprot id: A0A3B4EPM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

42514:amd1
gene id: 42514:amd1
uniprot id: A0A3B4C2V4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

42514:emc7
gene id: 42514:emc7
uniprot id: A0A3B4EH13
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

42514:bzw2
gene id: 42514:bzw2
uniprot id: A0A3B4DNB2
names: Similarity
messages: Belongs to the BZW family.

42514:pla2g4f.1
gene id: 42514:pla2g4f.1
uniprot id: A0A3B4D6H6
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

42514:serinc1
gene id: 42514:serinc1
uniprot id: A0A3B4E0I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

42514:slc1a6
gene id: 42514:slc1a6
uniprot id: A0A3B4ED17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

42514:LOC108410534
gene id: 42514:LOC108410534
uniprot id: A0A3B4EBZ1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:zfx
gene id: 42514:zfx
uniprot id: A0A3B4CK88
uniprot id: A0A3B4CKB7
names: Subcellular Location Annotation
messages: Nucleus

42514:atp2a1
gene id: 42514:atp2a1
uniprot id: A0A3B4D006
uniprot id: A0A3B4EAI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

f3
gene id: 42514:il17a/f3
uniprot id: A0A3B4DFU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

42514:timm13
gene id: 42514:timm13
uniprot id: A0A3B4BYT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

42514:unm sa1261
gene id: 42514:unm_sa1261
uniprot id: A0A3B4D108
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

42514:gstt1b
gene id: 42514:gstt1b
uniprot id: A0A3B4DZL6
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

42514:reep2
gene id: 42514:reep2
uniprot id: A0A3B4D5Z4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108429652
gene id: 42514:LOC108429652
uniprot id: A0A3B4CHA3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:atxn2l
gene id: 42514:atxn2l
uniprot id: A0A3B4CEI9
uniprot id: A0A3B4DZ62
names: Similarity
messages: Belongs to the ataxin-2 family.

42514:ube2b
gene id: 42514:ube2b
uniprot id: A0A3B4CFE5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:LOC108441623
gene id: 42514:LOC108441623
uniprot id: A0A3B4DB82
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

42514:mtfr2
gene id: 42514:mtfr2
uniprot id: A0A3B4CLQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

42514:LOC108430611
gene id: 42514:LOC108430611
uniprot id: A0A3B4BX07
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108412991
gene id: 42514:LOC108412991
uniprot id: A0A3B4DYP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

42514:mogs
gene id: 42514:mogs
uniprot id: A0A3B4EL95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

42514:uck2a
gene id: 42514:uck2a
uniprot id: A0A3B4EKG8
names: Similarity
messages: Belongs to the uridine kinase family.

42514:tspo
gene id: 42514:tspo
uniprot id: A0A3B4CG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

42514:pbrm1
gene id: 42514:pbrm1
uniprot id: A0A3B4C7W0
names: Subcellular Location Annotation
messages: Nucleus

42514:cdaa
gene id: 42514:cdaa
uniprot id: A0A3B4EEI6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

42514:erg
gene id: 42514:erg
uniprot id: A0A3B4CLM0
uniprot id: A0A3B4E6M4
uniprot id: A0A3B4E6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:cuedc2
gene id: 42514:cuedc2
uniprot id: A0A3B4BS48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

42514:ythdf3
gene id: 42514:ythdf3
uniprot id: A0A3B4CTL4
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

42514:peds1
gene id: 42514:peds1
uniprot id: A0A3B4E3S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

42514:LOC108440581
gene id: 42514:LOC108440581
uniprot id: A0A3B4D106
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:cdc42l2
gene id: 42514:cdc42l2
uniprot id: A0A3B4CGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

42514:emx1
gene id: 42514:emx1
uniprot id: A0A3B4CN29
names: Subcellular Location Annotation
messages: Nucleus

42514:tada2a
gene id: 42514:tada2a
uniprot id: A0A3B4CAZ5
uniprot id: A0A3B4DWS0
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108425458
gene id: 42514:LOC108425458
uniprot id: A0A3B4D4T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

42514:cert1b
gene id: 42514:cert1b
uniprot id: A0A3B4BV38
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

42514:tspan18a
gene id: 42514:tspan18a
uniprot id: A0A3B4CCT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:tspan2b
gene id: 42514:tspan2b
uniprot id: A0A3B4CVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:pth4
gene id: 42514:pth4
uniprot id: A0A3B4BZV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

42514:smim8
gene id: 42514:smim8
uniprot id: A0A3B4DD32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

42514:psmc1a
gene id: 42514:psmc1a
uniprot id: A0A3B4BRQ7
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:mvb12bb
gene id: 42514:mvb12bb
uniprot id: A0A3B4DEP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

42514:atp6v0ca
gene id: 42514:atp6v0ca
uniprot id: A0A3B4C427
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

42514:cfl1
gene id: 42514:cfl1
uniprot id: A0A3B4E9P4
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

42514:lig3
gene id: 42514:lig3
uniprot id: A0A3B4E3M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

42514:reep6
gene id: 42514:reep6
uniprot id: A0A3B4D2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

42514:pbx3b
gene id: 42514:pbx3b
uniprot id: A0A3B4DAU6
uniprot id: A0A3B4EL02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

42514:cdnf
gene id: 42514:cdnf
uniprot id: A0A3B4BVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

42514:atp6v0a2a
gene id: 42514:atp6v0a2a
uniprot id: A0A3B4DLU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

42514:LOC108412438
gene id: 42514:LOC108412438
uniprot id: A0A3B4BWW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

42514:LOC108414295
gene id: 42514:LOC108414295
uniprot id: A0A3B4EK85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:myclb
gene id: 42514:myclb
uniprot id: A0A3B4DMS3
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

42514:p2ry4
gene id: 42514:p2ry4
uniprot id: A0A3B4CR16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:foxa1
gene id: 42514:foxa1
uniprot id: A0A3B4BQ81
names: Subcellular Location Annotation
messages: Nucleus

42514:cnih1
gene id: 42514:cnih1
uniprot id: A0A3B4E923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

42514:LOC108429307
gene id: 42514:LOC108429307
uniprot id: A0A3B4BNU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

42514:cntnap1
gene id: 42514:cntnap1
uniprot id: A0A3B4E3Y5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

42514:ykt6
gene id: 42514:ykt6
uniprot id: A0A3B4EG20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

42514:rad23ab
gene id: 42514:rad23ab
uniprot id: A0A3B4CLF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Nucleus

42514:cnot6b
gene id: 42514:cnot6b
uniprot id: A0A3B4DB69
uniprot id: A0A3B4DDU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

42514:exosc2
gene id: 42514:exosc2
uniprot id: A0A3B4DYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

42514:fes
gene id: 42514:fes
uniprot id: A0A3B4CAW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

42514:rpl9
gene id: 42514:rpl9
uniprot id: A0A3B4DAC9
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

42514:esyt2a
gene id: 42514:esyt2a
uniprot id: A0A3B4CTV2
uniprot id: A0A3B4E8W1
uniprot id: A0A3B4EAA6
uniprot id: A0A3B4EAJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:pigl
gene id: 42514:pigl
uniprot id: A0A3B4BYV8
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

42514:nrp1a
gene id: 42514:nrp1a
uniprot id: A0A3B4DKM3
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:actr6
gene id: 42514:actr6
uniprot id: A0A3B4CSH7
names: Similarity
messages: Belongs to the actin family.

42514:ptpn12
gene id: 42514:ptpn12
uniprot id: A0A3B4BTF8
uniprot id: A0A3B4DJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.
messages: Cytoplasm
messages: Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.

42514:LOC108425192
gene id: 42514:LOC108425192
uniprot id: A0A3B4CC93
uniprot id: A0A3B4CC98
uniprot id: A0A3B4CEN3
uniprot id: A0A3B4DZ71
uniprot id: A0A3B4DZ81
uniprot id: A0A3B4E0B3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:adcy7
gene id: 42514:adcy7
uniprot id: A0A3B4D2M1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

42514:pcsk9
gene id: 42514:pcsk9
uniprot id: A0A3B4DFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Endosome
messages: Golgi apparatus
messages: Lysosome

42514:mdm2
gene id: 42514:mdm2
uniprot id: A0A3B4BWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

42514:sh3pxd2aa
gene id: 42514:sh3pxd2aa
uniprot id: A0A3B4BQQ2
uniprot id: A0A3B4BTK8
uniprot id: A0A3B4BTP2
uniprot id: A0A3B4DHR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm

42514:hhatlb
gene id: 42514:hhatlb
uniprot id: A0A3B4E6Q6
names: Subcellular Location Annotation
messages: Membrane

42514:tm6sf2
gene id: 42514:tm6sf2
uniprot id: A0A3B4CSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

42514:gipc1
gene id: 42514:gipc1
uniprot id: A0A3B4CC96
names: Similarity
messages: Belongs to the GIPC family.

42514:ntrk2b
gene id: 42514:ntrk2b
uniprot id: A0A3B4BPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:prickle1b
gene id: 42514:prickle1b
uniprot id: A0A3B4D1T3
uniprot id: A0A3B4EGY7
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

42514:vps53
gene id: 42514:vps53
uniprot id: A0A3B4DJP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

42514:thada
gene id: 42514:thada
uniprot id: A0A3B4CAD7
uniprot id: A0A3B4DW55
names: Function
names: Similarity
messages: Belongs to the THADA family.
messages: Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.

42514:LOC108439023
gene id: 42514:LOC108439023
uniprot id: A0A3B4CL80
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:efnb2a
gene id: 42514:efnb2a
uniprot id: A0A3B4DW93
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:emp2
gene id: 42514:emp2
uniprot id: A0A3B4C4A7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108443377
gene id: 42514:LOC108443377
uniprot id: A0A3B4EFV7
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

42514:map2k5
gene id: 42514:map2k5
uniprot id: A0A3B4DZA1
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:skap2
gene id: 42514:skap2
uniprot id: A0A3B4BSB1
names: Similarity
messages: Belongs to the SKAP family.

42514:ppdpfb
gene id: 42514:ppdpfb
uniprot id: A0A3B4E2F9
names: Similarity
messages: Belongs to the PPDPF family.

42514:trim65
gene id: 42514:trim65
uniprot id: A0A3B4DY20
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108444096
gene id: 42514:LOC108444096
uniprot id: A0A3B4EDL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:mgat1a
gene id: 42514:mgat1a
uniprot id: A0A3B4E5R3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

42514:LOC108426836
gene id: 42514:LOC108426836
uniprot id: A0A3B4DY47
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

42514:cpne2
gene id: 42514:cpne2
uniprot id: A0A3B4CHL0
names: Similarity
messages: Belongs to the copine family.

42514:fundc2
gene id: 42514:fundc2
uniprot id: A0A3B4D605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

42514:srp68
gene id: 42514:srp68
uniprot id: A0A3B4DEX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

42514:LOC108441187
gene id: 42514:LOC108441187
uniprot id: A0A3B4C793
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:ssbp1
gene id: 42514:ssbp1
uniprot id: A0A3B4CUV6
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

42514:trmt2a
gene id: 42514:trmt2a
uniprot id: A0A3B4CHK6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tppp3
gene id: 42514:tppp3
uniprot id: A0A3B4CBU9
names: Similarity
messages: Belongs to the TPPP family.

42514:ap1s3b
gene id: 42514:ap1s3b
uniprot id: A0A3B4E8E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

42514:si:ch73-267c23.10
gene id: 42514:si:ch73-267c23.10
uniprot id: A0A3B4DG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

42514:LOC108443952
gene id: 42514:LOC108443952
uniprot id: A0A3B4DAR5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:itpa
gene id: 42514:itpa
uniprot id: A0A3B4BMR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

42514:jakmip2
gene id: 42514:jakmip2
uniprot id: A0A3B4E0E3
names: Similarity
messages: Belongs to the JAKMIP family.

42514:LOC108435092
gene id: 42514:LOC108435092
uniprot id: A0A3B4CWL0
uniprot id: A0A3B4CWM4
uniprot id: A0A3B4CX95
uniprot id: A0A3B4EB26
names: Similarity
messages: Belongs to the SEC2 family.

42514:LOC108435264
gene id: 42514:LOC108435264
uniprot id: A0A3B4DDB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

42514:ddah2
gene id: 42514:ddah2
uniprot id: A0A3B4CBV9
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

42514:LOC108436498
gene id: 42514:LOC108436498
uniprot id: A0A3B4BUA1
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

42514:LOC108439431
gene id: 42514:LOC108439431
uniprot id: A0A3B4EEH8
names: Similarity
messages: Belongs to the multicopper oxidase family.

42514:LOC108425722
gene id: 42514:LOC108425722
uniprot id: A0A3B4CBB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:gad1b
gene id: 42514:gad1b
uniprot id: A0A3B4C0Y2
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

42514:si:ch1073-70f20.1
gene id: 42514:si:ch1073-70f20.1
uniprot id: A0A3B4DRV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

42514:camk4
gene id: 42514:camk4
uniprot id: A0A3B4BPM0
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108443108
gene id: 42514:LOC108443108
uniprot id: A0A3B4BYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:LOC108424920
gene id: 42514:LOC108424920
uniprot id: A0A3B4D1H6
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

42514:itgae.2
gene id: 42514:itgae.2
uniprot id: A0A3B4D623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

42514:p3h2
gene id: 42514:p3h2
uniprot id: A0A3B4ELN1
names: Similarity
messages: Belongs to the leprecan family.

42514:tnfsf14
gene id: 42514:tnfsf14
uniprot id: A0A3B4CP16
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:zgc:153441
gene id: 42514:zgc:153441
uniprot id: A0A3B4DCI2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:si:dkey-222f2.1
gene id: 42514:si:dkey-222f2.1
uniprot id: A0A3B4D0D4
names: Similarity
messages: Belongs to the intermediate filament family.

42514:pip4p1b
gene id: 42514:pip4p1b
uniprot id: A0A3B4EJF6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

42514:nfu1
gene id: 42514:nfu1
uniprot id: A0A3B4CUF9
names: Similarity
messages: Belongs to the NifU family.

42514:scamp3
gene id: 42514:scamp3
uniprot id: A0A3B4CHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

42514:hesx1
gene id: 42514:hesx1
uniprot id: A0A3B4ENI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

42514:soul5l
gene id: 42514:soul5l
uniprot id: A0A3B4BZ84
names: Similarity
messages: Belongs to the HEBP family.

42514:mapk1
gene id: 42514:mapk1
uniprot id: A0A3B4E7N0
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

42514:tfpia
gene id: 42514:tfpia
uniprot id: A0A3B4BRM0
names: Subcellular Location Annotation
messages: Secreted

42514:chdh
gene id: 42514:chdh
uniprot id: A0A3B4DNY3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

42514:LOC108436754
gene id: 42514:LOC108436754
uniprot id: A0A3B4EDT5
names: Similarity
messages: Belongs to the DTD family.

42514:LOC108411980
gene id: 42514:LOC108411980
uniprot id: A0A3B4DRE3
names: Similarity
messages: Belongs to the sulfatase family.

42514:efna1b
gene id: 42514:efna1b
uniprot id: A0A3B4ELT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:gpc6a
gene id: 42514:gpc6a
uniprot id: A0A3B4BNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

42514:LOC108443021
gene id: 42514:LOC108443021
uniprot id: A0A3B4DZP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

42514:erlin2
gene id: 42514:erlin2
uniprot id: A0A3B4DHL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Membrane

42514:diras1a
gene id: 42514:diras1a
uniprot id: A0A3B4D278
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:ankrd13a
gene id: 42514:ankrd13a
uniprot id: A0A3B4DLG8
names: Subcellular Location Annotation
messages: Membrane

42514:alg10
gene id: 42514:alg10
uniprot id: A0A3B4EP75
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108440950
gene id: 42514:LOC108440950
uniprot id: A0A3B4BTJ1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

42514:galr1b
gene id: 42514:galr1b
uniprot id: A0A3B4CCI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:hgfa
gene id: 42514:hgfa
uniprot id: A0A3B4DN28
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

42514:dgkzb
gene id: 42514:dgkzb
uniprot id: A0A3B4BPY3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

42514:ptger4c
gene id: 42514:ptger4c
uniprot id: A0A3B4BWQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:park7
gene id: 42514:park7
uniprot id: A0A3B4EMU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

42514:LOC108436231
gene id: 42514:LOC108436231
uniprot id: A0A3B4CLD8
names: Similarity
messages: Belongs to the DDIT4 family.

42514:atxn10
gene id: 42514:atxn10
uniprot id: A0A3B4EP41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
messages: perinuclear region

42514:pigk
gene id: 42514:pigk
uniprot id: A0A3B4CB68
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.

42514:LOC108426117
gene id: 42514:LOC108426117
uniprot id: A0A3B4DE34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:pole2
gene id: 42514:pole2
uniprot id: A0A3B4C7L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus
messages: Participates in DNA repair and in chromosomal DNA replication.

42514:wscd2
gene id: 42514:wscd2
uniprot id: A0A3B4DNH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Golgi apparatus membrane
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

42514:ywhaqa
gene id: 42514:ywhaqa
uniprot id: A0A3B4EFW3
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

42514:pou3f2a
gene id: 42514:pou3f2a
uniprot id: A0A3B4D2T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

42514:tmem176
gene id: 42514:tmem176
uniprot id: A0A3B4CIE8
names: Similarity
messages: Belongs to the MS4A family.

42514:lect2l
gene id: 42514:lect2l
uniprot id: A0A3B4ECH9
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

42514:med19b
gene id: 42514:med19b
uniprot id: A0A3B4DNA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:abi1b
gene id: 42514:abi1b
uniprot id: A0A3B4CH55
uniprot id: A0A3B4CIS3
uniprot id: A0A3B4E3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

42514:dynll1
gene id: 42514:dynll1
uniprot id: A0A3B4DF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

42514:bnip3la
gene id: 42514:bnip3la
uniprot id: A0A3B4BRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

42514:smarca5
gene id: 42514:smarca5
uniprot id: A0A3B4EJM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

42514:LOC108424738
gene id: 42514:LOC108424738
uniprot id: A0A3B4DEL2
names: Similarity
messages: Belongs to the heme oxygenase family.

42514:sts
gene id: 42514:sts
uniprot id: A0A3B4CZY6
names: Similarity
messages: Belongs to the sulfatase family.

42514:LOC108439097
gene id: 42514:LOC108439097
uniprot id: A0A3B4DWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

42514:ddr2l
gene id: 42514:ddr2l
uniprot id: A0A3B4CJS1
names: Subcellular Location Annotation
messages: Membrane

42514:marcksb
gene id: 42514:marcksb
uniprot id: A0A3B4EB09
names: Similarity
messages: Belongs to the MARCKS family.

42514:txnrd3
gene id: 42514:txnrd3
uniprot id: A0A3B4DDN6
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

42514:grk3
gene id: 42514:grk3
uniprot id: A0A3B4BSP0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

42514:trh
gene id: 42514:trh
uniprot id: A0A3B4DHA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

42514:LOC108428395
gene id: 42514:LOC108428395
uniprot id: A0A3B4E839
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108424030
gene id: 42514:LOC108424030
uniprot id: A0A3B4BT21
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:hmgn2
gene id: 42514:hmgn2
uniprot id: A0A3B4CTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

42514:flncb
gene id: 42514:flncb
uniprot id: A0A3B4BU81
uniprot id: A0A3B4BUD3
uniprot id: A0A3B4BUN4
uniprot id: A0A3B4DKZ9
names: Similarity
messages: Belongs to the filamin family.

42514:srp19
gene id: 42514:srp19
uniprot id: A0A3B4BTP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

42514:mfn2
gene id: 42514:mfn2
uniprot id: A0A3B4EKD3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

42514:slc22a18
gene id: 42514:slc22a18
uniprot id: A0A3B4D5N2
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108430250
gene id: 42514:LOC108430250
uniprot id: A0A3B4BV08
uniprot id: A0A3B4BV14
uniprot id: A0A3B4BY86
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

42514:LOC108423765
gene id: 42514:LOC108423765
uniprot id: A0A3B4CM00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

42514:per1b
gene id: 42514:per1b
uniprot id: A0A3B4C1Z2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:mpped2
gene id: 42514:mpped2
uniprot id: A0A3B4CI08
names: Similarity
messages: Belongs to the UPF0046 family.

42514:tmem121aa
gene id: 42514:tmem121aa
uniprot id: A0A3B4D7S2
names: Similarity
messages: Belongs to the TMEM121 family.

42514:grinab
gene id: 42514:grinab
uniprot id: A0A3B4CN57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

42514:chmp5b
gene id: 42514:chmp5b
uniprot id: A0A3B4CWU4
names: Similarity
messages: Belongs to the SNF7 family.

42514:tmem63c
gene id: 42514:tmem63c
uniprot id: A0A3B4CG83
uniprot id: A0A3B4E2U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

42514:colgalt2
gene id: 42514:colgalt2
uniprot id: A0A3B4EGK8
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

42514:trim71
gene id: 42514:trim71
uniprot id: A0A3B4CVE9
names: Similarity
messages: Belongs to the TRIM/RBCC family.

42514:marchf4
gene id: 42514:marchf4
uniprot id: A0A3B4E130
names: Subcellular Location Annotation
messages: Membrane

42514:im:7138535
gene id: 42514:im:7138535
uniprot id: A0A3B4CTM5
names: Similarity
messages: Belongs to the FAM98 family.

42514:postnb
gene id: 42514:postnb
uniprot id: A0A3B4BPT4
names: Subcellular Location Annotation
messages: extracellular matrix

42514:slc25a14
gene id: 42514:slc25a14
uniprot id: A0A3B4CFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:adra1d
gene id: 42514:adra1d
uniprot id: A0A3B4EPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

42514:atp5f1d
gene id: 42514:atp5f1d
uniprot id: A0A3B4CPP2
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

42514:bcr
gene id: 42514:bcr
uniprot id: A0A3B4CUD3
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

42514:si:ch211-157c3.4
gene id: 42514:si:ch211-157c3.4
uniprot id: A0A3B4EGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

42514:dlx1a
gene id: 42514:dlx1a
uniprot id: A0A3B4EAP4
names: Subcellular Location Annotation
messages: Nucleus

42514:mapk8a
gene id: 42514:mapk8a
uniprot id: A0A3B4BQE0
uniprot id: A0A3B4DFI9
uniprot id: A0A3B4DJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

42514:pcyt1bb
gene id: 42514:pcyt1bb
uniprot id: A0A3B4DY06
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

42514:clcn7
gene id: 42514:clcn7
uniprot id: A0A3B4EG85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

42514:pck1
gene id: 42514:pck1
uniprot id: A0A3B4C0P8
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

42514:wnt5a
gene id: 42514:wnt5a
uniprot id: A0A3B4E5L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:ube2g1a
gene id: 42514:ube2g1a
uniprot id: A0A3B4DWH3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:bpnt1
gene id: 42514:bpnt1
uniprot id: A0A3B4DWI6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

42514:LOC108441008
gene id: 42514:LOC108441008
uniprot id: A0A3B4D0I1
names: Similarity
messages: Belongs to the peptidase A1 family.

42514:pnpla7b
gene id: 42514:pnpla7b
uniprot id: A0A3B4E9H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:sumo1
gene id: 42514:sumo1
uniprot id: A0A3B4CVL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

42514:mrpl20
gene id: 42514:mrpl20
uniprot id: A0A3B4CI74
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

42514:ndufs2
gene id: 42514:ndufs2
uniprot id: A0A3B4E6F4
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

42514:spaca4l
gene id: 42514:spaca4l
uniprot id: A0A3B4DZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

42514:ube2d4
gene id: 42514:ube2d4
uniprot id: A0A3B4D0J1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:hacd4
gene id: 42514:hacd4
uniprot id: A0A3B4CQ40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:mut
gene id: 42514:mut
uniprot id: A0A3B4E6S5
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

42514:nfe2l3
gene id: 42514:nfe2l3
uniprot id: A0A3B4DIT4
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

42514:mybl1
gene id: 42514:mybl1
uniprot id: A0A3B4CYR4
names: Subcellular Location Annotation
messages: Nucleus

42514:lyn
gene id: 42514:lyn
uniprot id: A0A3B4CZ93
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:slc26a11
gene id: 42514:slc26a11
uniprot id: A0A3B4CZT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

42514:hoxb6a
gene id: 42514:hoxb6a
uniprot id: A0A3B4CDI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:lrwd1
gene id: 42514:lrwd1
uniprot id: A0A3B4E417
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

42514:jag2b
gene id: 42514:jag2b
uniprot id: A0A3B4DEF1
uniprot id: A0A3B4EM83
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

42514:eif3hb
gene id: 42514:eif3hb
uniprot id: A0A3B4EGI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

42514:kcnk3b
gene id: 42514:kcnk3b
uniprot id: A0A3B4CIY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:slc25a22b
gene id: 42514:slc25a22b
uniprot id: A0A3B4CDS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:hpdb
gene id: 42514:hpdb
uniprot id: A0A3B4DWE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

42514:pi4kb
gene id: 42514:pi4kb
uniprot id: A0A3B4D1Z6
uniprot id: A0A3B4D5E6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

42514:fbxo34
gene id: 42514:fbxo34
uniprot id: A0A3B4DJY8
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

42514:mmp13b
gene id: 42514:mmp13b
uniprot id: A0A3B4DU34
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

42514:hyi
gene id: 42514:hyi
uniprot id: A0A3B4CDQ9
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

42514:tmed9
gene id: 42514:tmed9
uniprot id: A0A3B4D5Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108412554
gene id: 42514:LOC108412554
uniprot id: A0A3B4BS62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

42514:LOC108431035
gene id: 42514:LOC108431035
uniprot id: A0A3B4DB80
uniprot id: A0A3B4DFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:mctp2a
gene id: 42514:mctp2a
uniprot id: A0A3B4E389
names: Subcellular Location Annotation
messages: Membrane

42514:fgf1a
gene id: 42514:fgf1a
uniprot id: A0A3B4DPZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

42514:LOC108437237
gene id: 42514:LOC108437237
uniprot id: A0A3B4D7W4
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

42514:polr3glb
gene id: 42514:polr3glb
uniprot id: A0A3B4BSF0
uniprot id: A0A3B4DKJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Nucleus

42514:cenph
gene id: 42514:cenph
uniprot id: A0A3B4CRC7
uniprot id: A0A3B4E7M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

42514:hoxd3a
gene id: 42514:hoxd3a
uniprot id: A0A3B4CT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

42514:cplx4c
gene id: 42514:cplx4c
uniprot id: A0A3B4D634
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

42514:crabp2a
gene id: 42514:crabp2a
uniprot id: A0A3B4CQB1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:LOC108423534
gene id: 42514:LOC108423534
uniprot id: A0A3B4DL40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:LOC108440226
gene id: 42514:LOC108440226
uniprot id: A0A3B4C331
names: Similarity
messages: Belongs to the globin family.

42514:LOC108442749
gene id: 42514:LOC108442749
uniprot id: A0A3B4DFQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:stk17a
gene id: 42514:stk17a
uniprot id: A0A3B4BP06
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:nr2f5
gene id: 42514:nr2f5
uniprot id: A0A3B4DF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:scfd1
gene id: 42514:scfd1
uniprot id: A0A3B4CR96
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

42514:dpcd
gene id: 42514:dpcd
uniprot id: A0A3B4BZ45
names: Similarity
messages: Belongs to the DPCD family.

42514:rnf20
gene id: 42514:rnf20
uniprot id: A0A3B4EH44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

42514:slc26a5
gene id: 42514:slc26a5
uniprot id: A0A3B4CHY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

42514:mtmr9
gene id: 42514:mtmr9
uniprot id: A0A3B4EKL7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

42514:usp37
gene id: 42514:usp37
uniprot id: A0A3B4DWK9
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:exosc1
gene id: 42514:exosc1
uniprot id: A0A3B4C3M4
names: Subcellular Location Annotation
messages: Cytoplasm

42514:tmem230a
gene id: 42514:tmem230a
uniprot id: A0A3B4ECJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

42514:cks1b
gene id: 42514:cks1b
uniprot id: A0A3B4DN58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

42514:csgalnact2
gene id: 42514:csgalnact2
uniprot id: A0A3B4CGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

42514:mfsd6a
gene id: 42514:mfsd6a
uniprot id: A0A3B4CS46
uniprot id: A0A3B4CSS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

42514:tmem11
gene id: 42514:tmem11
uniprot id: A0A3B4C757
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Plays a role in mitochondrial morphogenesis.

42514:cacfd1
gene id: 42514:cacfd1
uniprot id: A0A3B4E7K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

42514:tmem54a
gene id: 42514:tmem54a
uniprot id: A0A3B4D3J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

42514:LOC108426351
gene id: 42514:LOC108426351
uniprot id: A0A3B4DMC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

42514:mindy4
gene id: 42514:mindy4
uniprot id: A0A3B4E6A9
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

42514:nemp1
gene id: 42514:nemp1
uniprot id: A0A3B4DAK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

42514:fzr1b
gene id: 42514:fzr1b
uniprot id: A0A3B4E713
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

42514:tmlhe
gene id: 42514:tmlhe
uniprot id: A0A3B4DQD9
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

42514:cygb2
gene id: 42514:cygb2
uniprot id: A0A3B4EPL8
names: Similarity
messages: Belongs to the globin family.

42514:sdhaf2
gene id: 42514:sdhaf2
uniprot id: A0A3B4CE81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

42514:dhodh
gene id: 42514:dhodh
uniprot id: A0A3B4C6E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

42514:waplb
gene id: 42514:waplb
uniprot id: A0A3B4EJ10
names: Similarity
messages: Belongs to the WAPL family.

42514:ndufb2
gene id: 42514:ndufb2
uniprot id: A0A3B4BXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

42514:nova2
gene id: 42514:nova2
uniprot id: A0A3B4BWF2
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

42514:psmc5
gene id: 42514:psmc5
uniprot id: A0A3B4C103
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:prox3
gene id: 42514:prox3
uniprot id: A0A3B4EA20
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108418154
gene id: 42514:LOC108418154
uniprot id: A0A3B4EEB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

42514:vps28
gene id: 42514:vps28
uniprot id: A0A3B4D2U7
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

42514:cxcr2
gene id: 42514:cxcr2
uniprot id: A0A3B4BQ64
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:fgf6a
gene id: 42514:fgf6a
uniprot id: A0A3B4DJ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

42514:dnm3a
gene id: 42514:dnm3a
uniprot id: A0A3B4DIS5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

42514:rps8a
gene id: 42514:rps8a
uniprot id: A0A3B4DS56
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

42514:fpr1
gene id: 42514:fpr1
uniprot id: A0A3B4EJ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

42514:strada
gene id: 42514:strada
uniprot id: A0A3B4CLI8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

42514:adss2
gene id: 42514:adss2
uniprot id: A0A3B4CBV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

42514:ganc
gene id: 42514:ganc
uniprot id: A0A3B4E3G9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

42514:ptpn2b
gene id: 42514:ptpn2b
uniprot id: A0A3B4EJZ5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

42514:LOC108426377
gene id: 42514:LOC108426377
uniprot id: A0A3B4DNS5
names: Similarity
messages: Belongs to the TPPP family.

42514:slc7a3b
gene id: 42514:slc7a3b
uniprot id: A0A3B4EAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

42514:atpv0e2
gene id: 42514:atpv0e2
uniprot id: A0A3B4CKM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

42514:prdm9
gene id: 42514:prdm9
uniprot id: A0A3B4CUP6
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108424642
gene id: 42514:LOC108424642
uniprot id: A0A3B4BPD4
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

42514:zgc:113054
gene id: 42514:zgc:113054
uniprot id: A0A3B4DJ74
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

42514:si:ch211-243g18.2
gene id: 42514:si:ch211-243g18.2
uniprot id: A0A3B4CIN1
names: Similarity
messages: Belongs to the intermediate filament family.

42514:trappc5
gene id: 42514:trappc5
uniprot id: A0A3B4EFR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

42514:llgl2
gene id: 42514:llgl2
uniprot id: A0A3B4DBG7
uniprot id: A0A3B4DBI3
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

42514:map4l
gene id: 42514:map4l
uniprot id: A0A3B4BS55
uniprot id: A0A3B4BVF0
names: Subcellular Location Annotation
messages: cytoskeleton

42514:flvcr2a
gene id: 42514:flvcr2a
uniprot id: A0A3B4DKD2
names: Subcellular Location Annotation
messages: Membrane

42514:slc4a11
gene id: 42514:slc4a11
uniprot id: A0A3B4E2W2
uniprot id: A0A3B4E458
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

42514:mmgt1
gene id: 42514:mmgt1
uniprot id: A0A3B4CTR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

42514:afg1la
gene id: 42514:afg1la
uniprot id: A0A3B4BM81
names: Similarity
messages: Belongs to the AFG1 ATPase family.

42514:tbc1d7
gene id: 42514:tbc1d7
uniprot id: A0A3B4BR85
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

42514:LOC108433903
gene id: 42514:LOC108433903
uniprot id: A0A3B4D9M5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

42514:LOC108438290
gene id: 42514:LOC108438290
uniprot id: A0A3B4D9I4
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:c1galt1a
gene id: 42514:c1galt1a
uniprot id: A0A3B4D1N8
names: Subcellular Location Annotation
messages: Membrane

42514:cilp2
gene id: 42514:cilp2
uniprot id: A0A3B4CRX3
names: Subcellular Location Annotation
messages: extracellular matrix

42514:eif4a3
gene id: 42514:eif4a3
uniprot id: A0A3B4DJ65
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:ebf1a
gene id: 42514:ebf1a
uniprot id: A0A3B4CPU8
uniprot id: A0A3B4CPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

42514:dapk2b
gene id: 42514:dapk2b
uniprot id: A0A3B4DXG0
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108430666
gene id: 42514:LOC108430666
uniprot id: A0A3B4CTR4
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

42514:LOC108428158
gene id: 42514:LOC108428158
uniprot id: A0A3B4DQ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Homodimer.

42514:hnrnph1l
gene id: 42514:hnrnph1l
uniprot id: A0A3B4C996
names: Subcellular Location Annotation
messages: nucleoplasm

42514:cdc14b
gene id: 42514:cdc14b
uniprot id: A0A3B4BNL9
uniprot id: A0A3B4BSB8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

42514:eps8l3b
gene id: 42514:eps8l3b
uniprot id: A0A3B4EE83
names: Similarity
messages: Belongs to the EPS8 family.

42514:fshb
gene id: 42514:fshb
uniprot id: A0A3B4E115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

42514:fam135b
gene id: 42514:fam135b
uniprot id: A0A3B4CBG5
names: Similarity
messages: Belongs to the FAM135 family.

42514:LOC108425194
gene id: 42514:LOC108425194
uniprot id: A0A3B4CAA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

42514:moxd1
gene id: 42514:moxd1
uniprot id: A0A3B4DX58
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

42514:otpb
gene id: 42514:otpb
uniprot id: A0A3B4DFK1
names: Subcellular Location Annotation
messages: Nucleus

42514:prps1a
gene id: 42514:prps1a
uniprot id: A0A3B4BSW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

42514:hspa4b
gene id: 42514:hspa4b
uniprot id: A0A3B4DQ12
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:u2af2b
gene id: 42514:u2af2b
uniprot id: A0A3B4DBU1
uniprot id: A0A3B4EKW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

42514:gnaq
gene id: 42514:gnaq
uniprot id: A0A3B4BPT5
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

42514:palm3
gene id: 42514:palm3
uniprot id: A0A3B4D884
names: Similarity
messages: Belongs to the paralemmin family.

42514:ctsf
gene id: 42514:ctsf
uniprot id: A0A3B4BU27
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:slc1a8a
gene id: 42514:slc1a8a
uniprot id: A0A3B4EG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

42514:ikbke
gene id: 42514:ikbke
uniprot id: A0A3B4BWZ3
names: Subcellular Location Annotation
messages: Cytoplasm

42514:hsd11b2
gene id: 42514:hsd11b2
uniprot id: A0A3B4CB71
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:drgx
gene id: 42514:drgx
uniprot id: A0A3B4DJY3
names: Subcellular Location Annotation
messages: Nucleus

42514:trim36
gene id: 42514:trim36
uniprot id: A0A3B4DXR1
names: Subcellular Location Annotation
messages: cytoskeleton

42514:nme6
gene id: 42514:nme6
uniprot id: A0A3B4DBP5
names: Similarity
messages: Belongs to the NDK family.

42514:LOC108414109
gene id: 42514:LOC108414109
uniprot id: A0A3B4EK85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:LOC108430662
gene id: 42514:LOC108430662
uniprot id: A0A3B4E908
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

42514:cul2
gene id: 42514:cul2
uniprot id: A0A3B4DIT9
names: Similarity
messages: Belongs to the cullin family.

42514:tap1
gene id: 42514:tap1
uniprot id: A0A3B4DEA2
names: Subcellular Location Annotation
messages: Membrane

42514:raf1b
gene id: 42514:raf1b
uniprot id: A0A3B4DJH7
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

42514:ppm1ba
gene id: 42514:ppm1ba
uniprot id: A0A3B4CAU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

42514:LOC108440166
gene id: 42514:LOC108440166
uniprot id: A0A3B4E561
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

42514:rab4b
gene id: 42514:rab4b
uniprot id: A0A3B4BXK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

42514:LOC108412396
gene id: 42514:LOC108412396
uniprot id: A0A3B4DTK9
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:snupn
gene id: 42514:snupn
uniprot id: A0A3B4EK03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

42514:mpc2b
gene id: 42514:mpc2b
uniprot id: A0A3B4D1P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

42514:LOC108425984
gene id: 42514:LOC108425984
uniprot id: A0A3B4D8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

42514:aifm1
gene id: 42514:aifm1
uniprot id: A0A3B4BSS8
uniprot id: A0A3B4BSY2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

42514:cdca7a
gene id: 42514:cdca7a
uniprot id: A0A3B4CTT3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:slc6a7
gene id: 42514:slc6a7
uniprot id: A0A3B4CEI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:kif7
gene id: 42514:kif7
uniprot id: A0A3B4C756
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:celf4
gene id: 42514:celf4
uniprot id: A0A3B4D358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

42514:pigf
gene id: 42514:pigf
uniprot id: A0A3B4DK82
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:spi1b
gene id: 42514:spi1b
uniprot id: A0A3B4E0U4
uniprot id: A0A3B4E277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:cd63
gene id: 42514:cd63
uniprot id: A0A3B4DBX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:smarca2
gene id: 42514:smarca2
uniprot id: A0A3B4DWH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

42514:ddx51
gene id: 42514:ddx51
uniprot id: A0A3B4E5U0
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

42514:fam49a
gene id: 42514:fam49a
uniprot id: A0A3B4DIT3
uniprot id: A0A3B4DMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

42514:LOC108442255
gene id: 42514:LOC108442255
uniprot id: A0A3B4D0A7
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

42514:zdhhc22
gene id: 42514:zdhhc22
uniprot id: A0A3B4E4N4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:LOC108424901
gene id: 42514:LOC108424901
uniprot id: A0A3B4CZC5
uniprot id: A0A3B4ED04
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108432285
gene id: 42514:LOC108432285
uniprot id: A0A3B4CSM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

42514:med28
gene id: 42514:med28
uniprot id: A0A3B4C3X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

42514:ints9
gene id: 42514:ints9
uniprot id: A0A3B4C323
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

42514:si:dkey-204f11.64
gene id: 42514:si:dkey-204f11.64
uniprot id: A0A3B4CZ24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

42514:rybpa
gene id: 42514:rybpa
uniprot id: A0A3B4ELV9
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108410533
gene id: 42514:LOC108410533
uniprot id: A0A3B4ED42
names: Similarity
messages: Belongs to the BCL7 family.

42514:si:ch211-168f7.5
gene id: 42514:si:ch211-168f7.5
uniprot id: A0A3B4D1W6
names: Similarity
messages: Belongs to the dapper family.

42514:LOC108430851
gene id: 42514:LOC108430851
uniprot id: A0A3B4DLM1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

42514:nhp2
gene id: 42514:nhp2
uniprot id: A0A3B4C8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

42514:zgc:110410
gene id: 42514:zgc:110410
uniprot id: A0A3B4EK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

42514:LOC108434183
gene id: 42514:LOC108434183
uniprot id: A0A3B4BY06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

42514:LOC108432827
gene id: 42514:LOC108432827
uniprot id: A0A3B4ED62
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:bcl2l16
gene id: 42514:bcl2l16
uniprot id: A0A3B4CYY0
names: Similarity
messages: Belongs to the Bcl-2 family.

42514:LOC108432761
gene id: 42514:LOC108432761
uniprot id: A0A3B4D6W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:psmc6
gene id: 42514:psmc6
uniprot id: A0A3B4D800
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:nr3c1
gene id: 42514:nr3c1
uniprot id: A0A3B4BZT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

42514:abcg5
gene id: 42514:abcg5
uniprot id: A0A3B4C883
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

42514:LOC108432931
gene id: 42514:LOC108432931
uniprot id: A0A3B4DFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

42514:ywhae1
gene id: 42514:ywhae1
uniprot id: A0A3B4BXG4
uniprot id: A0A3B4DK98
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

42514:csmd2
gene id: 42514:csmd2
uniprot id: A0A3B4DM36
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:adra2a
gene id: 42514:adra2a
uniprot id: A0A3B4E5U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:tbpl1
gene id: 42514:tbpl1
uniprot id: A0A3B4EJG3
names: Similarity
messages: Belongs to the TBP family.

42514:ptbp1b
gene id: 42514:ptbp1b
uniprot id: A0A3B4D1A1
names: Subcellular Location Annotation
messages: Nucleus

42514:sulf2b
gene id: 42514:sulf2b
uniprot id: A0A3B4DGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack

42514:fgf17
gene id: 42514:fgf17
uniprot id: A0A3B4CZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

42514:gsr
gene id: 42514:gsr
uniprot id: A0A3B4E590
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

42514:tyw3
gene id: 42514:tyw3
uniprot id: A0A3B4DD57
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

42514:trappc13
gene id: 42514:trappc13
uniprot id: A0A3B4BVA1
uniprot id: A0A3B4DL38
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

42514:LOC108437279
gene id: 42514:LOC108437279
uniprot id: A0A3B4D3M5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:ap4s1
gene id: 42514:ap4s1
uniprot id: A0A3B4CQT7
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

42514:elovl8b
gene id: 42514:elovl8b
uniprot id: A0A3B4E886
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

42514:LOC108424337
gene id: 42514:LOC108424337
uniprot id: A0A3B4D0C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

42514:LOC108443084
gene id: 42514:LOC108443084
uniprot id: A0A3B4DWG8
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:ifih1
gene id: 42514:ifih1
uniprot id: A0A3B4EF69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

42514:tead3b
gene id: 42514:tead3b
uniprot id: A0A3B4DKF4
uniprot id: A0A3B4DKH0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

42514:slco2a1
gene id: 42514:slco2a1
uniprot id: A0A3B4EMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

42514:poc5
gene id: 42514:poc5
uniprot id: A0A3B4CBR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

42514:slx4
gene id: 42514:slx4
uniprot id: A0A3B4E5F6
names: Similarity
messages: Belongs to the SLX4 family.

42514:mmd2a
gene id: 42514:mmd2a
uniprot id: A0A3B4CZF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:acsf3
gene id: 42514:acsf3
uniprot id: A0A3B4DVN8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:smim22
gene id: 42514:smim22
uniprot id: A0A3B4DVB1
names: Subcellular Location Annotation
messages: Membrane

42514:slc35b4
gene id: 42514:slc35b4
uniprot id: A0A3B4DGC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

42514:oxsm
gene id: 42514:oxsm
uniprot id: A0A3B4E474
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

42514:tgfb3
gene id: 42514:tgfb3
uniprot id: A0A3B4BUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

42514:capn5b
gene id: 42514:capn5b
uniprot id: A0A3B4CHS2
names: Similarity
messages: Belongs to the peptidase C2 family.

42514:inhbaa
gene id: 42514:inhbaa
uniprot id: A0A3B4DJQ7
names: Similarity
messages: Belongs to the TGF-beta family.

42514:si:ch73-139j3.4
gene id: 42514:si:ch73-139j3.4
uniprot id: A0A3B4DPB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:senp2
gene id: 42514:senp2
uniprot id: A0A3B4C9M7
names: Similarity
messages: Belongs to the peptidase C48 family.

42514:aoc2
gene id: 42514:aoc2
uniprot id: A0A3B4C959
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

42514:si:ch73-212j7.1
gene id: 42514:si:ch73-212j7.1
uniprot id: A0A3B4D2G9
uniprot id: A0A3B4EIW9
names: Similarity
messages: Belongs to the CEP170 family.

42514:eif2s1a
gene id: 42514:eif2s1a
uniprot id: A0A3B4C8I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

42514:stx12l
gene id: 42514:stx12l
uniprot id: A0A3B4E1W7
names: Similarity
messages: Belongs to the syntaxin family.

42514:jpt1b
gene id: 42514:jpt1b
uniprot id: A0A3B4CHF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

42514:ralbb
gene id: 42514:ralbb
uniprot id: A0A3B4E932
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:LOC108437275
gene id: 42514:LOC108437275
uniprot id: A0A3B4D1H0
names: Subcellular Location Annotation
messages: Membrane

42514:aspn
gene id: 42514:aspn
uniprot id: A0A3B4BRZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

42514:ptafr
gene id: 42514:ptafr
uniprot id: A0A3B4D2U8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

42514:zgc:92606
gene id: 42514:zgc:92606
uniprot id: A0A3B4E8A6
names: Similarity
messages: Belongs to the ATG8 family.

42514:gpd1l
gene id: 42514:gpd1l
uniprot id: A0A3B4DRK3
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

42514:atp6v1ab
gene id: 42514:atp6v1ab
uniprot id: A0A3B4EA49
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

42514:LOC108440217
gene id: 42514:LOC108440217
uniprot id: A0A3B4C8Y6
names: Similarity
messages: Belongs to the globin family.

42514:LOC108415901
gene id: 42514:LOC108415901
uniprot id: A0A3B4D406
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108412461
gene id: 42514:LOC108412461
uniprot id: A0A3B4BZH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

42514:LOC108424660
gene id: 42514:LOC108424660
uniprot id: A0A3B4BRB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

42514:rpl26
gene id: 42514:rpl26
uniprot id: A0A3B4EJV2
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

42514:slc25a23b
gene id: 42514:slc25a23b
uniprot id: A0A3B4D3P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:l1cama
gene id: 42514:l1cama
uniprot id: A0A3B4CXD3
uniprot id: A0A3B4D1M0
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

42514:gtf2h4
gene id: 42514:gtf2h4
uniprot id: A0A3B4DAW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

42514:pithd1
gene id: 42514:pithd1
uniprot id: A0A3B4D7J1
names: Similarity
messages: Belongs to the PITHD1 family.

42514:ppm1f
gene id: 42514:ppm1f
uniprot id: A0A3B4E9W4
names: Similarity
messages: Belongs to the PP2C family.

42514:bmpr1bb
gene id: 42514:bmpr1bb
uniprot id: A0A3B4CS59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:ncana
gene id: 42514:ncana
uniprot id: A0A3B4EI28
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:picalmb
gene id: 42514:picalmb
uniprot id: A0A3B4C7Y3
uniprot id: A0A3B4C820
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

42514:LOC108439997
gene id: 42514:LOC108439997
uniprot id: A0A3B4EFY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:sardh
gene id: 42514:sardh
uniprot id: A0A3B4E3S7
names: Similarity
messages: Belongs to the GcvT family.

42514:LOC108443187
gene id: 42514:LOC108443187
uniprot id: A0A3B4DLK4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:smu1a
gene id: 42514:smu1a
uniprot id: A0A3B4C8X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

42514:anapc4
gene id: 42514:anapc4
uniprot id: A0A3B4BZN6
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

42514:hapln3
gene id: 42514:hapln3
uniprot id: A0A3B4EAC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ngfb
gene id: 42514:ngfb
uniprot id: A0A3B4BU23
names: Similarity
messages: Belongs to the NGF-beta family.

42514:slc25a44a
gene id: 42514:slc25a44a
uniprot id: A0A3B4EMG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:pex7
gene id: 42514:pex7
uniprot id: A0A3B4DQF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Peroxisome matrix
messages: cytosol

42514:dmrt3a
gene id: 42514:dmrt3a
uniprot id: A0A3B4CDK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

42514:ponzr2
gene id: 42514:ponzr2
uniprot id: A0A3B4DAP8
names: Similarity
messages: Belongs to the cornifelin family.

42514:LOC108443125
gene id: 42514:LOC108443125
uniprot id: A0A3B4EEK1
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

42514:rnf10
gene id: 42514:rnf10
uniprot id: A0A3B4DW82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

42514:tsc22d2
gene id: 42514:tsc22d2
uniprot id: A0A3B4CGW2
uniprot id: A0A3B4DZG4
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

42514:cd247
gene id: 42514:cd247
uniprot id: A0A3B4DS25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

42514:bud13
gene id: 42514:bud13
uniprot id: A0A3B4CFP5
names: Similarity
messages: Belongs to the CWC26 family.

42514:pdcd5
gene id: 42514:pdcd5
uniprot id: A0A3B4EM08
names: Similarity
messages: Belongs to the PDCD5 family.

42514:ehd4
gene id: 42514:ehd4
uniprot id: A0A3B4CQ04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

42514:slc25a15a
gene id: 42514:slc25a15a
uniprot id: A0A3B4BZE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:grk7a
gene id: 42514:grk7a
uniprot id: A0A3B4E6W8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

42514:matk
gene id: 42514:matk
uniprot id: A0A3B4DMS6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:arf3b
gene id: 42514:arf3b
uniprot id: A0A3B4D532
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

42514:timm9
gene id: 42514:timm9
uniprot id: A0A3B4DL04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

42514:dip2cb
gene id: 42514:dip2cb
uniprot id: A0A3B4E7Z6
names: Similarity
messages: Belongs to the DIP2 family.

42514:LOC108426899
gene id: 42514:LOC108426899
uniprot id: A0A3B4DRC1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108431923
gene id: 42514:LOC108431923
uniprot id: A0A3B4DUK0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

42514:ppp2caa
gene id: 42514:ppp2caa
uniprot id: A0A3B4DQ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

42514:nhsl1a
gene id: 42514:nhsl1a
uniprot id: A0A3B4CLI1
uniprot id: A0A3B4E5G1
names: Similarity
messages: Belongs to the NHS family.

42514:kcnk6
gene id: 42514:kcnk6
uniprot id: A0A3B4C8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:plrdgb
gene id: 42514:plrdgb
uniprot id: A0A3B4E062
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

42514:abracl
gene id: 42514:abracl
uniprot id: A0A3B4EKE4
names: Similarity
messages: Belongs to the costars family.

42514:ttc27
gene id: 42514:ttc27
uniprot id: A0A3B4DSD4
names: Similarity
messages: Belongs to the TTC27 family.

42514:ptpn4b
gene id: 42514:ptpn4b
uniprot id: A0A3B4CA26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

42514:gdf10b
gene id: 42514:gdf10b
uniprot id: A0A3B4D2D7
names: Similarity
messages: Belongs to the TGF-beta family.

42514:itpr2
gene id: 42514:itpr2
uniprot id: A0A3B4E5B7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

42514:med10
gene id: 42514:med10
uniprot id: A0A3B4D5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:dsg2l
gene id: 42514:dsg2l
uniprot id: A0A3B4CAC3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

42514:tubb2b
gene id: 42514:tubb2b
uniprot id: A0A3B4CZ40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:znf711
gene id: 42514:znf711
uniprot id: A0A3B4DEX0
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108424401
gene id: 42514:LOC108424401
uniprot id: A0A3B4E2Y3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

42514:LOC108429008
gene id: 42514:LOC108429008
uniprot id: A0A3B4CRC0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:hsp90ab1
gene id: 42514:hsp90ab1
uniprot id: A0A3B4DTC7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

42514:pkig
gene id: 42514:pkig
uniprot id: A0A3B4CPZ6
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

42514:si:dkey-175m17.7
gene id: 42514:si:dkey-175m17.7
uniprot id: A0A3B4C526
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

42514:elapor2b
gene id: 42514:elapor2b
uniprot id: A0A3B4BYF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

42514:LOC108436198
gene id: 42514:LOC108436198
uniprot id: A0A3B4CMU4
names: Similarity
messages: Belongs to the FAM154 family.

42514:rpl38
gene id: 42514:rpl38
uniprot id: A0A3B4DH84
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

42514:mcm5
gene id: 42514:mcm5
uniprot id: A0A3B4CZ78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

42514:cog2
gene id: 42514:cog2
uniprot id: A0A3B4CEW1
names: Similarity
messages: Belongs to the COG2 family.

42514:nanog
gene id: 42514:nanog
uniprot id: A0A3B4DBE9
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108416945
gene id: 42514:LOC108416945
uniprot id: A0A3B4E3Z6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:nup210
gene id: 42514:nup210
uniprot id: A0A3B4D0M0
names: Similarity
messages: Belongs to the NUP210 family.

42514:irgq2
gene id: 42514:irgq2
uniprot id: A0A3B4BUL2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

42514:rorb
gene id: 42514:rorb
uniprot id: A0A3B4BT28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:kalrna
gene id: 42514:kalrna
uniprot id: A0A3B4CNE7
uniprot id: A0A3B4E6K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

42514:si:ch211-26b3.4
gene id: 42514:si:ch211-26b3.4
uniprot id: A0A3B4DKG3
names: Similarity
messages: Belongs to the CNKSR family.

42514:anapc11
gene id: 42514:anapc11
uniprot id: A0A3B4DBM6
names: Similarity
messages: Belongs to the RING-box family.

42514:slc25a34
gene id: 42514:slc25a34
uniprot id: A0A3B4BK58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:ndufc1
gene id: 42514:ndufc1
uniprot id: A0A3B4DF39
names: Similarity
names: Subunit
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.

42514:dtymk
gene id: 42514:dtymk
uniprot id: A0A3B4EQS0
names: Similarity
messages: Belongs to the thymidylate kinase family.

42514:msrb3
gene id: 42514:msrb3
uniprot id: A0A3B4BVC8
uniprot id: A0A3B4DN13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

42514:plppr3a
gene id: 42514:plppr3a
uniprot id: A0A3B4DU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:nr2c2
gene id: 42514:nr2c2
uniprot id: A0A3B4BP50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:mst1
gene id: 42514:mst1
uniprot id: A0A3B4C326
names: Caution
names: Similarity
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108437516
gene id: 42514:LOC108437516
uniprot id: A0A3B4CIR9
names: Subcellular Location Annotation
messages: Membrane

42514:dennd5a
gene id: 42514:dennd5a
uniprot id: A0A3B4EMT5
uniprot id: A0A3B4EN46
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:mfsd10
gene id: 42514:mfsd10
uniprot id: A0A3B4C9V8
names: Subcellular Location Annotation
messages: Membrane

42514:bcl9
gene id: 42514:bcl9
uniprot id: A0A3B4EMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

42514:cpped1
gene id: 42514:cpped1
uniprot id: A0A3B4C200
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.

42514:ppp2cb
gene id: 42514:ppp2cb
uniprot id: A0A3B4D6N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

42514:rhpn2
gene id: 42514:rhpn2
uniprot id: A0A3B4CAQ4
names: Similarity
messages: Belongs to the RHPN family.

42514:polr2b
gene id: 42514:polr2b
uniprot id: A0A3B4C4Z1
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

42514:LOC108420326
gene id: 42514:LOC108420326
uniprot id: A0A3B4CJF0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:mcee
gene id: 42514:mcee
uniprot id: A0A3B4CUN1
uniprot id: A0A3B4CYF0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

42514:slc1a2b
gene id: 42514:slc1a2b
uniprot id: A0A3B4DH86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

42514:mrpl12
gene id: 42514:mrpl12
uniprot id: A0A3B4CEY3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

42514:ldb2a
gene id: 42514:ldb2a
uniprot id: A0A3B4EMV7
names: Similarity
messages: Belongs to the LDB family.

42514:gatb
gene id: 42514:gatb
uniprot id: A0A3B4CUN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

42514:prkcea
gene id: 42514:prkcea
uniprot id: A0A3B4DPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

42514:cd248b
gene id: 42514:cd248b
uniprot id: A0A3B4C333
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:zgc:158689
gene id: 42514:zgc:158689
uniprot id: A0A3B4E6E2
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

42514:zgc:153675
gene id: 42514:zgc:153675
uniprot id: A0A3B4C8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

42514:kif14
gene id: 42514:kif14
uniprot id: A0A3B4C964
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:sncb
gene id: 42514:sncb
uniprot id: A0A3B4DRY0
names: Similarity
messages: Belongs to the synuclein family.

42514:LOC108425763
gene id: 42514:LOC108425763
uniprot id: A0A3B4DW12
names: Similarity
messages: Belongs to the PPP1R15 family.

42514:tppp2
gene id: 42514:tppp2
uniprot id: A0A3B4C426
names: Similarity
messages: Belongs to the TPPP family.

42514:prok1
gene id: 42514:prok1
uniprot id: A0A3B4DJ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

42514:osbpl6
gene id: 42514:osbpl6
uniprot id: A0A3B4EDH6
names: Similarity
messages: Belongs to the OSBP family.

42514:LOC108429407
gene id: 42514:LOC108429407
uniprot id: A0A3B4D9J0
uniprot id: A0A3B4ELT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

42514:usp44
gene id: 42514:usp44
uniprot id: A0A3B4ERV0
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:LOC108441721
gene id: 42514:LOC108441721
uniprot id: A0A3B4CNM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:grin2cb
gene id: 42514:grin2cb
uniprot id: A0A3B4C9I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

42514:LOC108432107
gene id: 42514:LOC108432107
uniprot id: A0A3B4BQW9
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:bsk146
gene id: 42514:bsk146
uniprot id: A0A3B4EJS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

42514:sh2b1
gene id: 42514:sh2b1
uniprot id: A0A3B4CMF9
names: Similarity
messages: Belongs to the SH2B adapter family.

42514:rrs1
gene id: 42514:rrs1
uniprot id: A0A3B4CWB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

42514:mbtps1
gene id: 42514:mbtps1
uniprot id: A0A3B4E9M1
names: Similarity
messages: Belongs to the peptidase S8 family.

42514:slc20a1b
gene id: 42514:slc20a1b
uniprot id: A0A3B4BY99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

42514:draxin
gene id: 42514:draxin
uniprot id: A0A3B4EH16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord.
messages: Secreted

42514:si:ch211-87j1.4
gene id: 42514:si:ch211-87j1.4
uniprot id: A0A3B4DJE9
names: Similarity
messages: Belongs to the TMEM178 family.

42514:nt5c3a
gene id: 42514:nt5c3a
uniprot id: A0A3B4EJQ1
uniprot id: A0A3B4ELN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

42514:LOC108437321
gene id: 42514:LOC108437321
uniprot id: A0A3B4D081
names: Subcellular Location Annotation
messages: Membrane

42514:zgc:64051
gene id: 42514:zgc:64051
uniprot id: A0A3B4BW48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:prl
gene id: 42514:prl
uniprot id: A0A3B4CP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

42514:stambpb
gene id: 42514:stambpb
uniprot id: A0A3B4EER2
names: Similarity
messages: Belongs to the peptidase M67C family.

42514:cc2d1a
gene id: 42514:cc2d1a
uniprot id: A0A3B4DVJ0
names: Similarity
messages: Belongs to the CC2D1 family.

42514:pdzk1ip1
gene id: 42514:pdzk1ip1
uniprot id: A0A3B4ECZ5
names: Subcellular Location Annotation
messages: Membrane

42514:thg1l
gene id: 42514:thg1l
uniprot id: A0A3B4CD25
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

42514:otc
gene id: 42514:otc
uniprot id: A0A3B4DK13
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

42514:clcn5a
gene id: 42514:clcn5a
uniprot id: A0A3B4CBI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:agxtb
gene id: 42514:agxtb
uniprot id: A0A3B4BZ99
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

42514:senp6a
gene id: 42514:senp6a
uniprot id: A0A3B4CAC5
uniprot id: A0A3B4DYD0
names: Similarity
messages: Belongs to the peptidase C48 family.

42514:LOC108427197
gene id: 42514:LOC108427197
uniprot id: A0A3B4CW41
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:eif4enif1
gene id: 42514:eif4enif1
uniprot id: A0A3B4E406
names: Subcellular Location Annotation
messages: Cytoplasm

42514:pym1
gene id: 42514:pym1
uniprot id: A0A3B4CQE7
names: Similarity
names: Subunit
messages: Belongs to the pym family.
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

42514:hbp1
gene id: 42514:hbp1
uniprot id: A0A3B4ERG5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

42514:ccn1
gene id: 42514:ccn1
uniprot id: A0A3B4BTH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:LOC108443299
gene id: 42514:LOC108443299
uniprot id: A0A3B4DHJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:adam8a
gene id: 42514:adam8a
uniprot id: A0A3B4CAZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:arhgef12a
gene id: 42514:arhgef12a
uniprot id: A0A3B4BT72
uniprot id: A0A3B4DLM6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

42514:ssr2
gene id: 42514:ssr2
uniprot id: A0A3B4DQT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

42514:ufd1l
gene id: 42514:ufd1l
uniprot id: A0A3B4BQT3
names: Similarity
messages: Belongs to the UFD1 family.

42514:armc1l
gene id: 42514:armc1l
uniprot id: A0A3B4CNK1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

42514:fam114a2
gene id: 42514:fam114a2
uniprot id: A0A3B4E1X6
names: Similarity
messages: Belongs to the FAM114 family.

42514:sst6
gene id: 42514:sst6
uniprot id: A0A3B4EEJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

42514:LOC108425316
gene id: 42514:LOC108425316
uniprot id: A0A3B4BLI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:steap3
gene id: 42514:steap3
uniprot id: A0A3B4D2A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

42514:prr5a
gene id: 42514:prr5a
uniprot id: A0A3B4E5H0
names: Similarity
messages: Belongs to the PROTOR family.

42514:zgpat
gene id: 42514:zgpat
uniprot id: A0A3B4DSB6
names: Subcellular Location Annotation
messages: Nucleus

42514:amotl2a
gene id: 42514:amotl2a
uniprot id: A0A3B4DE42
names: Similarity
messages: Belongs to the angiomotin family.

42514:LOC108430275
gene id: 42514:LOC108430275
uniprot id: A0A3B4EPQ3
uniprot id: A0A3B4EQ88
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

42514:traf2b
gene id: 42514:traf2b
uniprot id: A0A3B4DAK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

42514:csnk2b
gene id: 42514:csnk2b
uniprot id: A0A3B4DAJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

42514:ap2a1
gene id: 42514:ap2a1
uniprot id: A0A3B4CPB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

42514:c27h18orf21
gene id: 42514:c27h18orf21
uniprot id: A0A3B4DIZ3
names: Similarity
messages: Belongs to the UPF0711 family.

42514:LOC108440056
gene id: 42514:LOC108440056
uniprot id: A0A3B4ECL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

42514:LOC108440221
gene id: 42514:LOC108440221
uniprot id: A0A3B4C3A2
names: Similarity
messages: Belongs to the globin family.

42514:LOC108439315
gene id: 42514:LOC108439315
uniprot id: A0A3B4DDQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:rxfp3.2b
gene id: 42514:rxfp3.2b
uniprot id: A0A3B4DUX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:upk1a
gene id: 42514:upk1a
uniprot id: A0A3B4BYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:hs3st1
gene id: 42514:hs3st1
uniprot id: A0A3B4C5Z8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:psmb5
gene id: 42514:psmb5
uniprot id: A0A3B4CWX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

42514:soul4
gene id: 42514:soul4
uniprot id: A0A3B4C024
names: Similarity
messages: Belongs to the HEBP family.

42514:LOC108442518
gene id: 42514:LOC108442518
uniprot id: A0A3B4C442
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

42514:fam83d
gene id: 42514:fam83d
uniprot id: A0A3B4BU43
names: Similarity
messages: Belongs to the FAM83 family.

42514:nupr1b
gene id: 42514:nupr1b
uniprot id: A0A3B4CC45
names: Similarity
messages: Belongs to the NUPR family.

42514:eef2kmt
gene id: 42514:eef2kmt
uniprot id: A0A3B4D563
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

42514:phf5a
gene id: 42514:phf5a
uniprot id: A0A3B4DTB3
names: Similarity
messages: Belongs to the PHF5 family.

42514:glra3
gene id: 42514:glra3
uniprot id: A0A3B4E2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

42514:gprin3
gene id: 42514:gprin3
uniprot id: A0A3B4CGN2
names: Function
messages: May be involved in neurite outgrowth.

42514:stat5b
gene id: 42514:stat5b
uniprot id: A0A3B4C5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

42514:pyyb
gene id: 42514:pyyb
uniprot id: A0A1I9HVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

42514:srfbp1
gene id: 42514:srfbp1
uniprot id: A0A3B4EQX0
names: Function
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

42514:mief2
gene id: 42514:mief2
uniprot id: A0A3B4CF36
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

42514:gng8
gene id: 42514:gng8
uniprot id: A0A3B4CGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

42514:clk4a
gene id: 42514:clk4a
uniprot id: A0A3B4BMA8
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:dpm1
gene id: 42514:dpm1
uniprot id: A0A3B4E2E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

42514:ppt1
gene id: 42514:ppt1
uniprot id: A0A3B4D802
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

42514:hspa9
gene id: 42514:hspa9
uniprot id: A0A3B4ENN0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:LOC108427446
gene id: 42514:LOC108427446
uniprot id: A0A3B4CE19
names: Similarity
messages: Belongs to the RASGRP family.

42514:mthfs
gene id: 42514:mthfs
uniprot id: A0A3B4DW17
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

42514:gja5b
gene id: 42514:gja5b
uniprot id: A0A3B4DFK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:stip1
gene id: 42514:stip1
uniprot id: A0A3B4EDI4
names: Subcellular Location Annotation
messages: Cytoplasm

42514:mrpl51
gene id: 42514:mrpl51
uniprot id: A0A3B4E502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.
messages: Mitochondrion

42514:ppifb
gene id: 42514:ppifb
uniprot id: A0A3B4DL70
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

42514:LOC108425536
gene id: 42514:LOC108425536
uniprot id: A0A3B4CVC7
uniprot id: A0A3B4ECR1
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108413752
gene id: 42514:LOC108413752
uniprot id: A0A3B4DQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

42514:fgf20b
gene id: 42514:fgf20b
uniprot id: A0A3B4E7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

42514:dbt
gene id: 42514:dbt
uniprot id: A0A3B4CZ64
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

42514:stoml2
gene id: 42514:stoml2
uniprot id: A0A3B4EFT2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

42514:LOC108436105
gene id: 42514:LOC108436105
uniprot id: A0A3B4CYB8
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108439342
gene id: 42514:LOC108439342
uniprot id: A0A3B4D9R0
names: Similarity
messages: Belongs to the peptidase M14 family.

42514:rbpms2a
gene id: 42514:rbpms2a
uniprot id: A0A3B4EL19
names: Subcellular Location Annotation
messages: Cytoplasm

42514:mrpl32
gene id: 42514:mrpl32
uniprot id: A0A3B4CEN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL32 family.
messages: Cytoplasm

42514:egr2a
gene id: 42514:egr2a
uniprot id: A0A3B4DZC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

42514:stmn4l
gene id: 42514:stmn4l
uniprot id: A0A3B4DQA5
names: Similarity
messages: Belongs to the stathmin family.

42514:si:dkeyp-9d4.3
gene id: 42514:si:dkeyp-9d4.3
uniprot id: A0A3B4DS16
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108423593
gene id: 42514:LOC108423593
uniprot id: A0A3B4D7A8
uniprot id: A0A3B4D7B8
names: Subcellular Location Annotation
messages: Nucleus

42514:mcoln2
gene id: 42514:mcoln2
uniprot id: A0A3B4CA80
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

42514:phyhipla
gene id: 42514:phyhipla
uniprot id: A0A3B4EJT6
names: Similarity
messages: Belongs to the PHYHIP family.

42514:trappc4
gene id: 42514:trappc4
uniprot id: A0A3B4DPS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

42514:cdc20
gene id: 42514:cdc20
uniprot id: A0A3B4D3F5
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

42514:mipb
gene id: 42514:mipb
uniprot id: A0A3B4DPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:snx25
gene id: 42514:snx25
uniprot id: A0A3B4EI83
names: Similarity
messages: Belongs to the sorting nexin family.

42514:ldb3b
gene id: 42514:ldb3b
uniprot id: A0A3B4DNW4
uniprot id: A0A3B4DPU3
names: Subcellular Location Annotation
messages: Z line

42514:LOC108436451
gene id: 42514:LOC108436451
uniprot id: A0A3B4DNV2
names: Similarity
messages: Belongs to the intermediate filament family.

42514:rgma
gene id: 42514:rgma
uniprot id: A0A3B4E359
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

42514:LOC108431133
gene id: 42514:LOC108431133
uniprot id: A0A3B4D1N4
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:LOC108431780
gene id: 42514:LOC108431780
uniprot id: A0A3B4CL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

42514:LOC108436548
gene id: 42514:LOC108436548
uniprot id: A0A3B4BT13
uniprot id: A0A3B4DJX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

42514:bcl7bb
gene id: 42514:bcl7bb
uniprot id: A0A3B4EPM3
names: Similarity
messages: Belongs to the BCL7 family.

42514:car15
gene id: 42514:car15
uniprot id: A0A3B4CG36
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

42514:clul1
gene id: 42514:clul1
uniprot id: A0A3B4DA71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

42514:pxmp4
gene id: 42514:pxmp4
uniprot id: A0A3B4DHH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

42514:si:ch211-45c16.2
gene id: 42514:si:ch211-45c16.2
uniprot id: A0A3B4DZ41
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

42514:hdac3
gene id: 42514:hdac3
uniprot id: A0A3B4D146
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

42514:ca7
gene id: 42514:ca7
uniprot id: A0A3B4BT95
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

42514:fabp1a
gene id: 42514:fabp1a
uniprot id: A0A3B4DZJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

42514:cfap298
gene id: 42514:cfap298
uniprot id: A0A3B4ECE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

42514:aqp9b
gene id: 42514:aqp9b
uniprot id: A0A3B4EBN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:nog1
gene id: 42514:nog1
uniprot id: A0A3B4CMG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

42514:edc3
gene id: 42514:edc3
uniprot id: A0A3B4CTB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

42514:LOC108444509
gene id: 42514:LOC108444509
uniprot id: A0A3B4EM65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

42514:LOC108444149
gene id: 42514:LOC108444149
uniprot id: A0A3B4E9I1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:LOC108427721
gene id: 42514:LOC108427721
uniprot id: A0A3B4EDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:arid1b
gene id: 42514:arid1b
uniprot id: A0A3B4EGE7
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108424272
gene id: 42514:LOC108424272
uniprot id: A0A3B4E8S7
names: Subcellular Location Annotation
messages: Nucleus

42514:tmprss13b
gene id: 42514:tmprss13b
uniprot id: A0A3B4DV65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:cavin4b
gene id: 42514:cavin4b
uniprot id: A0A3B4C577
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

42514:ccdc93
gene id: 42514:ccdc93
uniprot id: A0A3B4EG73
names: Similarity
messages: Belongs to the CCDC93 family.

42514:dact3a
gene id: 42514:dact3a
uniprot id: A0A3B4CS02
names: Similarity
messages: Belongs to the dapper family.

42514:LOC108411523
gene id: 42514:LOC108411523
uniprot id: A0A3B4D4S5
names: Similarity
messages: Belongs to the peptidase S8 family.

42514:apc2
gene id: 42514:apc2
uniprot id: A0A3B4EFG9
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

42514:psmc3
gene id: 42514:psmc3
uniprot id: A0A3B4EGH1
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:gask1b
gene id: 42514:gask1b
uniprot id: A0A3B4CRG4
names: Similarity
messages: Belongs to the GASK family.

42514:ipo8
gene id: 42514:ipo8
uniprot id: A0A3B4DPL4
names: Subcellular Location Annotation
messages: Cytoplasm

42514:slc2a9l2
gene id: 42514:slc2a9l2
uniprot id: A0A3B4C7S7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:nek3
gene id: 42514:nek3
uniprot id: A0A3B4BWD9
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108431792
gene id: 42514:LOC108431792
uniprot id: A0A3B4CJR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

42514:pla2g15
gene id: 42514:pla2g15
uniprot id: A0A3B4DU03
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

42514:hmga2
gene id: 42514:hmga2
uniprot id: A0A3B4DN08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

42514:mgst2
gene id: 42514:mgst2
uniprot id: A0A3B4EQ43
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:tmem97
gene id: 42514:tmem97
uniprot id: A0A3B4BYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

42514:cnpy1
gene id: 42514:cnpy1
uniprot id: A0A3B4CMU7
names: Similarity
messages: Belongs to the canopy family.

42514:LOC108436332
gene id: 42514:LOC108436332
uniprot id: A0A3B4DXC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

42514:LOC108437308
gene id: 42514:LOC108437308
uniprot id: A0A3B4D2E2
names: Similarity
messages: Belongs to the TGF-beta family.

42514:rpain
gene id: 42514:rpain
uniprot id: A0A3B4BUE4
names: Subcellular Location Annotation
messages: Nucleus

42514:pgpep1
gene id: 42514:pgpep1
uniprot id: A0A3B4D7B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

42514:ccz1
gene id: 42514:ccz1
uniprot id: A0A3B4BU89
names: Similarity
messages: Belongs to the CCZ1 family.

42514:mfsd8l2
gene id: 42514:mfsd8l2
uniprot id: A0A3B4E462
names: Subcellular Location Annotation
messages: Membrane

42514:tpst1
gene id: 42514:tpst1
uniprot id: A0A3B4DNF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

42514:entpd5a
gene id: 42514:entpd5a
uniprot id: A0A3B4E3Y0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

42514:ppp1r12c
gene id: 42514:ppp1r12c
uniprot id: A0A3B4DG72
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

42514:si:ch211-113j14.1
gene id: 42514:si:ch211-113j14.1
uniprot id: A0A3B4EF23
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:mitfb
gene id: 42514:mitfb
uniprot id: A0A3B4BYC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

42514:ppil2
gene id: 42514:ppil2
uniprot id: A0A3B4E9Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

42514:hadh
gene id: 42514:hadh
uniprot id: A0A3B4CPX1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

42514:fzd5
gene id: 42514:fzd5
uniprot id: A0A3B4D8K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

42514:eml1
gene id: 42514:eml1
uniprot id: A0A3B4CKQ3
uniprot id: A0A3B4CMX4
uniprot id: A0A3B4E5X5
names: Similarity
messages: Belongs to the WD repeat EMAP family.

42514:opn1sw2
gene id: 42514:opn1sw2
uniprot id: A0A3B4BY98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

42514:il17d
gene id: 42514:il17d
uniprot id: A0A3B4DPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

42514:LOC108434124
gene id: 42514:LOC108434124
uniprot id: A0A3B4DXE4
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:tmem205
gene id: 42514:tmem205
uniprot id: A0A3B4BQ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

42514:LOC108426721
gene id: 42514:LOC108426721
uniprot id: A0A3B4CL53
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

42514:LOC108425424
gene id: 42514:LOC108425424
uniprot id: A0A3B4D7S8
names: Function
names: Subcellular Location Annotation
messages: Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
messages: Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
messages: Secreted

42514:tfdp1b
gene id: 42514:tfdp1b
uniprot id: A0A3B4BYH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

42514:cacng8b
gene id: 42514:cacng8b
uniprot id: A0A3B4CKS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

42514:tdrd3
gene id: 42514:tdrd3
uniprot id: A0A3B4D836
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1.

42514:adgrl2a
gene id: 42514:adgrl2a
uniprot id: A0A3B4CF14
names: Subcellular Location Annotation
messages: Membrane

42514:rhbdd3
gene id: 42514:rhbdd3
uniprot id: A0A3B4CBV3
names: Subcellular Location Annotation
messages: Membrane

42514:kcnc1b
gene id: 42514:kcnc1b
uniprot id: A0A3B4BM53
uniprot id: A0A3B4BQ49
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108412307
gene id: 42514:LOC108412307
uniprot id: A0A3B4DYY2
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6c family.

42514:cstf1
gene id: 42514:cstf1
uniprot id: A0A3B4CTW2
names: Subcellular Location Annotation
messages: Nucleus

42514:itpr3
gene id: 42514:itpr3
uniprot id: A0A3B4EJE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

42514:urad
gene id: 42514:urad
uniprot id: A0A3B4EHN9
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

42514:kif25
gene id: 42514:kif25
uniprot id: A0A3B4CWD5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:pmm2
gene id: 42514:pmm2
uniprot id: A0A3B4C725
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

42514:ptgir
gene id: 42514:ptgir
uniprot id: A0A3B4DN56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:scnm1
gene id: 42514:scnm1
uniprot id: A0A3B4DTL2
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: nucleoplasm

42514:LOC108414960
gene id: 42514:LOC108414960
uniprot id: A0A3B4DNJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

42514:apln
gene id: 42514:apln
uniprot id: A0A3B4CSG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apelin family.
messages: extracellular space

42514:LOC108444058
gene id: 42514:LOC108444058
uniprot id: A0A3B4D091
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108434837
gene id: 42514:LOC108434837
uniprot id: A0A3B4DWB1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

42514:wasf3b
gene id: 42514:wasf3b
uniprot id: A0A3B4EIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

42514:hacd2
gene id: 42514:hacd2
uniprot id: A0A3B4DBB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:ptger4b
gene id: 42514:ptger4b
uniprot id: A0A3B4CVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

42514:tap2a
gene id: 42514:tap2a
uniprot id: A0A3B4C872
names: Subcellular Location Annotation
messages: Membrane

42514:tmbim4
gene id: 42514:tmbim4
uniprot id: A0A3B4BS35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

42514:acd
gene id: 42514:acd
uniprot id: A0A3B4BTM1
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

42514:mrps24
gene id: 42514:mrps24
uniprot id: A0A3B4EHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

42514:nptx2a
gene id: 42514:nptx2a
uniprot id: A0A3B4CIZ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:vbp1
gene id: 42514:vbp1
uniprot id: A0A3B4DY90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

42514:evla
gene id: 42514:evla
uniprot id: A0A3B4CME4
uniprot id: A0A3B4CP15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

42514:traf3
gene id: 42514:traf3
uniprot id: A0A3B4E945
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

42514:atp2b1a
gene id: 42514:atp2b1a
uniprot id: A0A3B4BNY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:arid1aa
gene id: 42514:arid1aa
uniprot id: A0A3B4D855
names: Subcellular Location Annotation
messages: Nucleus

42514:pfklb
gene id: 42514:pfklb
uniprot id: A0A3B4DK19
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108430948
gene id: 42514:LOC108430948
uniprot id: A0A3B4C3B8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

42514:stk17b
gene id: 42514:stk17b
uniprot id: A0A3B4EN98
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:ltv1
gene id: 42514:ltv1
uniprot id: A0A3B4E361
names: Similarity
messages: Belongs to the LTV1 family.

42514:grm1a
gene id: 42514:grm1a
uniprot id: A0A3B4DMC7
uniprot id: A0A3B4DNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

42514:pik3r3b
gene id: 42514:pik3r3b
uniprot id: A0A3B4DQK3
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

42514:cdr2a
gene id: 42514:cdr2a
uniprot id: A0A3B4E6L8
names: Similarity
messages: Belongs to the CDR2 family.

42514:efnb1
gene id: 42514:efnb1
uniprot id: A0A3B4BM39
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ythdf1
gene id: 42514:ythdf1
uniprot id: A0A3B4C6C3
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

42514:ninj2
gene id: 42514:ninj2
uniprot id: A0A3B4DNU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

42514:exo5
gene id: 42514:exo5
uniprot id: A0A3B4BWQ0
names: Similarity
messages: Belongs to the EXO5 family.

42514:tm7sf2
gene id: 42514:tm7sf2
uniprot id: A0A3B4DDX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

42514:cux2b
gene id: 42514:cux2b
uniprot id: A0A3B4DJ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

42514:tpd52l2b
gene id: 42514:tpd52l2b
uniprot id: A0A3B4E1A4
names: Similarity
messages: Belongs to the TPD52 family.

42514:lmnb2
gene id: 42514:lmnb2
uniprot id: A0A3B4EED5
names: Similarity
messages: Belongs to the intermediate filament family.

42514:acvr2aa
gene id: 42514:acvr2aa
uniprot id: A0A3B4DQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:camk1a
gene id: 42514:camk1a
uniprot id: A0A3B4DRT5
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:ccr7
gene id: 42514:ccr7
uniprot id: A0A3B4C974
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

42514:LOC108414659
gene id: 42514:LOC108414659
uniprot id: A0A3B4CP83
names: Similarity
messages: Belongs to the peptidase A1 family.

42514:mrpl35
gene id: 42514:mrpl35
uniprot id: A0A3B4CLP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

42514:srsf1a
gene id: 42514:srsf1a
uniprot id: A0A3B4EE04
names: Similarity
messages: Belongs to the splicing factor SR family.

42514:pigh
gene id: 42514:pigh
uniprot id: A0A3B4DPJ6
names: Similarity
messages: Belongs to the PIGH family.

42514:jph1b
gene id: 42514:jph1b
uniprot id: A0A3B4CLJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

42514:pfkla
gene id: 42514:pfkla
uniprot id: A0A3B4CEW0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:pus10
gene id: 42514:pus10
uniprot id: A0A3B4C9R8
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

42514:mmp15b
gene id: 42514:mmp15b
uniprot id: A0A3B4ECF6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

42514:LOC108410481
gene id: 42514:LOC108410481
uniprot id: A0A3B4EGF5
names: Similarity
messages: Belongs to the LCA5 family.

42514:pgm5
gene id: 42514:pgm5
uniprot id: A0A3B4CDJ8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

42514:tet1
gene id: 42514:tet1
uniprot id: A0A3B4EMD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

42514:zgc:194282
gene id: 42514:zgc:194282
uniprot id: A0A3B4CE01
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:wee1
gene id: 42514:wee1
uniprot id: A0A3B4E4J4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

42514:atp7a
gene id: 42514:atp7a
uniprot id: A0A3B4EEV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

42514:parvab
gene id: 42514:parvab
uniprot id: A0A3B4E073
names: Similarity
messages: Belongs to the parvin family.

42514:taf5
gene id: 42514:taf5
uniprot id: A0A3B4CLT5
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

42514:LOC108435180
gene id: 42514:LOC108435180
uniprot id: A0A3B4E6S3
names: Similarity
messages: Belongs to the BZW family.

42514:mcm2
gene id: 42514:mcm2
uniprot id: A0A3B4D274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

42514:tpra
gene id: 42514:tpra
uniprot id: A0A3B4E8X5
names: Similarity
messages: Belongs to the TPR family.

42514:neu4
gene id: 42514:neu4
uniprot id: A0A3B4DL41
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

42514:tecpr1b
gene id: 42514:tecpr1b
uniprot id: A0A3B4E4U7
names: Similarity
messages: Belongs to the TECPR1 family.

42514:LOC108435954
gene id: 42514:LOC108435954
uniprot id: A0A3B4C030
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:xkrx
gene id: 42514:xkrx
uniprot id: A0A3B4E6Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:eogt
gene id: 42514:eogt
uniprot id: A0A3B4CDL4
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

42514:fam20cb
gene id: 42514:fam20cb
uniprot id: A0A3B4DP15
names: Similarity
messages: Belongs to the FAM20 family.

42514:cd9a
gene id: 42514:cd9a
uniprot id: A0A3B4EJR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

42514:tmem168a
gene id: 42514:tmem168a
uniprot id: A0A3B4DDA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane
messages: Nucleus membrane

42514:amfra
gene id: 42514:amfra
uniprot id: A0A3B4DHP1
names: Subcellular Location Annotation
messages: Membrane

42514:polr2g
gene id: 42514:polr2g
uniprot id: A0A3B4D6M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

42514:dusp1
gene id: 42514:dusp1
uniprot id: A0A3B4E7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

42514:gls2b
gene id: 42514:gls2b
uniprot id: A0A3B4DDG5
uniprot id: A0A3B4DH90
names: Similarity
messages: Belongs to the glutaminase family.

42514:myt1b
gene id: 42514:myt1b
uniprot id: A0A3B4DK20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

42514:cers2b
gene id: 42514:cers2b
uniprot id: A0A3B4E582
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

42514:LOC108436390
gene id: 42514:LOC108436390
uniprot id: A0A3B4DSH6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108440218
gene id: 42514:LOC108440218
uniprot id: A0A3B4C3V5
names: Similarity
messages: Belongs to the globin family.

42514:ngfa
gene id: 42514:ngfa
uniprot id: A0A3B4CXW1
names: Similarity
messages: Belongs to the NGF-beta family.

42514:ghitm
gene id: 42514:ghitm
uniprot id: A0A3B4CNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

42514:ppdpfa
gene id: 42514:ppdpfa
uniprot id: A0A3B4BRG2
names: Similarity
messages: Belongs to the PPDPF family.

42514:si:dkey-234i14.3
gene id: 42514:si:dkey-234i14.3
uniprot id: A0A3B4E264
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:zfp36l1a
gene id: 42514:zfp36l1a
uniprot id: A0A3B4CI79
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

42514:ins
gene id: 42514:ins
uniprot id: A0A3B4DUP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

42514:dmbx1a
gene id: 42514:dmbx1a
uniprot id: A0A3B4DMB0
names: Subcellular Location Annotation
messages: Nucleus

42514:ccnjl
gene id: 42514:ccnjl
uniprot id: A0A3B4C9J0
names: Similarity
messages: Belongs to the cyclin family.

42514:paqr7b
gene id: 42514:paqr7b
uniprot id: A0A3B4CZX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:eif6
gene id: 42514:eif6
uniprot id: A0A3B4DSN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

42514:rabep1
gene id: 42514:rabep1
uniprot id: A0A3B4E1G1
uniprot id: A0A3B4E1H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

42514:slc6a2
gene id: 42514:slc6a2
uniprot id: A0A3B4D3D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:pus7l
gene id: 42514:pus7l
uniprot id: A0A3B4D3N2
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

42514:enoph1
gene id: 42514:enoph1
uniprot id: A0A3B4CFQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

42514:csnk1g1
gene id: 42514:csnk1g1
uniprot id: A0A3B4EBV0
uniprot id: A0A3B4ECZ4
uniprot id: A0A3B4ED24
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

42514:atp6ap1la
gene id: 42514:atp6ap1la
uniprot id: A0A3B4EN85
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

42514:prlra
gene id: 42514:prlra
uniprot id: A0A3B4ECI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

42514:LOC108423911
gene id: 42514:LOC108423911
uniprot id: A0A3B4E0A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

42514:eif3f
gene id: 42514:eif3f
uniprot id: A0A3B4D5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

42514:tsfm
gene id: 42514:tsfm
uniprot id: A0A3B4CEB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

42514:spcs3
gene id: 42514:spcs3
uniprot id: A0A3B4DW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:nme5
gene id: 42514:nme5
uniprot id: A0A3B4DIH6
names: Similarity
messages: Belongs to the NDK family.

42514:trim3b
gene id: 42514:trim3b
uniprot id: A0A3B4CHR7
uniprot id: A0A3B4E2W1
names: Similarity
messages: Belongs to the TRIM/RBCC family.

42514:adra1ba
gene id: 42514:adra1ba
uniprot id: A0A3B4CAS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

42514:hebp2
gene id: 42514:hebp2
uniprot id: A0A3B4E9L4
names: Similarity
messages: Belongs to the HEBP family.

42514:si:dkey-6i22.5
gene id: 42514:si:dkey-6i22.5
uniprot id: A0A3B4D979
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

42514:sept5b
gene id: 42514:sept5b
uniprot id: A0A3B4DLS3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

42514:pim2
gene id: 42514:pim2
uniprot id: A0A3B4EGS5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

42514:rbfox3a
gene id: 42514:rbfox3a
uniprot id: A0A3B4C7W7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

42514:lgr4
gene id: 42514:lgr4
uniprot id: A0A3B4CEQ5
names: Subcellular Location Annotation
messages: Membrane

42514:phospho1
gene id: 42514:phospho1
uniprot id: A0A3B4C7U9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

42514:nme3
gene id: 42514:nme3
uniprot id: A0A3B4C6H2
names: Similarity
messages: Belongs to the NDK family.

42514:nxf1
gene id: 42514:nxf1
uniprot id: A0A3B4C1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

42514:si
gene id: 42514:si
uniprot id: A0A3B4CQB8
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tpmt.1
gene id: 42514:tpmt.1
uniprot id: A0A3B4EHI3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.

42514:pbx2
gene id: 42514:pbx2
uniprot id: A0A3B4DF99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

42514:cacng4b
gene id: 42514:cacng4b
uniprot id: A0A3B4E457
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

42514:LOC108440225
gene id: 42514:LOC108440225
uniprot id: A0A3B4C6Z7
names: Similarity
messages: Belongs to the globin family.

42514:slc66a1
gene id: 42514:slc66a1
uniprot id: A0A3B4E147
names: Subcellular Location Annotation
messages: Membrane

42514:sypb
gene id: 42514:sypb
uniprot id: A0A3B4CGL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

42514:ptgfr
gene id: 42514:ptgfr
uniprot id: A0A3B4DV41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:mid1ip1b
gene id: 42514:mid1ip1b
uniprot id: A0A3B4ED23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

42514:LOC108424863
gene id: 42514:LOC108424863
uniprot id: A0A3B4EJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

42514:LOC108426790
gene id: 42514:LOC108426790
uniprot id: A0A3B4E151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

42514:pfdn4
gene id: 42514:pfdn4
uniprot id: A0A3B4CWI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

42514:tmed2
gene id: 42514:tmed2
uniprot id: A0A3B4C914
uniprot id: A0A3B4DV98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

42514:LOC108440424
gene id: 42514:LOC108440424
uniprot id: A0A3B4ELT1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:LOC108423685
gene id: 42514:LOC108423685
uniprot id: A0A3B4E2E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL.
messages: Secreted

42514:trmt6
gene id: 42514:trmt6
uniprot id: A0A3B4CPZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

42514:crabp1a
gene id: 42514:crabp1a
uniprot id: A0A3B4D7E1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:gpbp1l1
gene id: 42514:gpbp1l1
uniprot id: A0A3B4BYU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

42514:tars2
gene id: 42514:tars2
uniprot id: A0A3B4DW07
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

42514:oafa
gene id: 42514:oafa
uniprot id: A0A3B4DHI4
names: Similarity
messages: Belongs to the OAF family.

42514:immp1l
gene id: 42514:immp1l
uniprot id: A0A3B4BPT7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

42514:ppp2r5d
gene id: 42514:ppp2r5d
uniprot id: A0A3B4C3W3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

42514:magl
gene id: 42514:magl
uniprot id: A0A3B4CRG7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:glula
gene id: 42514:glula
uniprot id: A0A3B4ED78
names: Similarity
messages: Belongs to the glutamine synthetase family.

42514:LOC108434966
gene id: 42514:LOC108434966
uniprot id: A0A3B4DE12
names: Similarity
messages: Belongs to the dysbindin family.

42514:spdya
gene id: 42514:spdya
uniprot id: A0A3B4D2R7
names: Similarity
messages: Belongs to the Speedy/Ringo family.

42514:med24
gene id: 42514:med24
uniprot id: A0A3B4BPB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

42514:tmem167a
gene id: 42514:tmem167a
uniprot id: A0A3B4BUU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

42514:actn3b
gene id: 42514:actn3b
uniprot id: A0A3B4DQC4
names: Similarity
messages: Belongs to the alpha-actinin family.

42514:calr
gene id: 42514:calr
uniprot id: A0A3B4E0P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

42514:avpr2aa
gene id: 42514:avpr2aa
uniprot id: A0A3B4EB67
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:opn6b
gene id: 42514:opn6b
uniprot id: A0A3B4CNS7
names: Subcellular Location Annotation
messages: Membrane

42514:fermt3b
gene id: 42514:fermt3b
uniprot id: A0A3B4BR39
names: Similarity
messages: Belongs to the kindlin family.

42514:pdyn
gene id: 42514:pdyn
uniprot id: A0A3B4CWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opioid activity and may have anti-apoptotic effect.
messages: Secreted

42514:zgc:112294
gene id: 42514:zgc:112294
uniprot id: A0A3B4DDC9
names: Subcellular Location Annotation
messages: Membrane

42514:cdca8
gene id: 42514:cdca8
uniprot id: A0A3B4EFN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

42514:pdia6
gene id: 42514:pdia6
uniprot id: A0A3B4CT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

42514:LOC108431611
gene id: 42514:LOC108431611
uniprot id: A0A3B4EQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

42514:ptgesl
gene id: 42514:ptgesl
uniprot id: A0A3B4C1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

42514:LOC108428979
gene id: 42514:LOC108428979
uniprot id: A0A3B4CWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:rhpn1
gene id: 42514:rhpn1
uniprot id: A0A3B4BN40
names: Similarity
messages: Belongs to the RHPN family.

42514:eva1bb
gene id: 42514:eva1bb
uniprot id: A0A3B4DF16
names: Similarity
messages: Belongs to the EVA1 family.

42514:glra1
gene id: 42514:glra1
uniprot id: A0A3B4D4Q8
uniprot id: A0A3B4EEB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

42514:prr5b
gene id: 42514:prr5b
uniprot id: A0A3B4BTZ8
uniprot id: A0A3B4BXB6
names: Similarity
messages: Belongs to the PROTOR family.

42514:ap4m1
gene id: 42514:ap4m1
uniprot id: A0A3B4DIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal.
messages: Early endosome
messages: trans-Golgi network membrane

42514:cdk8
gene id: 42514:cdk8
uniprot id: A0A3B4D2Q5
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:mdm1
gene id: 42514:mdm1
uniprot id: A0A3B4EN93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM1 family.
messages: Nucleus
messages: centriole

42514:gpr137bb
gene id: 42514:gpr137bb
uniprot id: A0A3B4DT65
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

42514:specc1lb
gene id: 42514:specc1lb
uniprot id: A0A3B4BRH2
uniprot id: A0A3B4BRJ8
uniprot id: A0A3B4BUX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

42514:mtor
gene id: 42514:mtor
uniprot id: A0A3B4DE66
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

42514:itgb3a
gene id: 42514:itgb3a
uniprot id: A0A3B4DYP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

42514:api5
gene id: 42514:api5
uniprot id: A0A3B4CFR0
names: Similarity
messages: Belongs to the API5 family.

42514:tysnd1
gene id: 42514:tysnd1
uniprot id: A0A3B4DKK5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

42514:coro2ba
gene id: 42514:coro2ba
uniprot id: A0A3B4CD18
uniprot id: A0A3B4CEU1
uniprot id: A0A3B4E031
names: Similarity
messages: Belongs to the WD repeat coronin family.

42514:scarb1
gene id: 42514:scarb1
uniprot id: A0A3B4BYC4
names: Similarity
messages: Belongs to the CD36 family.

42514:tmem53
gene id: 42514:tmem53
uniprot id: A0A3B4DHX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

42514:nap1l1
gene id: 42514:nap1l1
uniprot id: A0A3B4DR32
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

42514:kcnn4
gene id: 42514:kcnn4
uniprot id: A0A3B4EI48
names: Subcellular Location Annotation
messages: Membrane

42514:ckma
gene id: 42514:ckma
uniprot id: A0A3B4EH25
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

42514:xdh
gene id: 42514:xdh
uniprot id: A0A3B4D7U7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

42514:daxx
gene id: 42514:daxx
uniprot id: A0A3B4DRD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

42514:syt16
gene id: 42514:syt16
uniprot id: A0A3B4CPS5
names: Similarity
messages: Belongs to the synaptotagmin family.

42514:LOC108411210
gene id: 42514:LOC108411210
uniprot id: A0A3B4CAB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:shroom3
gene id: 42514:shroom3
uniprot id: A0A3B4CLT8
uniprot id: A0A3B4E6R2
uniprot id: A0A3B4E878
uniprot id: A0A3B4E891
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

42514:si:dkey-202e22.2
gene id: 42514:si:dkey-202e22.2
uniprot id: A0A3B4DZB2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:lmln
gene id: 42514:lmln
uniprot id: A0A3B4C688
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

42514:cpt1ab
gene id: 42514:cpt1ab
uniprot id: A0A3B4BZQ4
uniprot id: A0A3B4DQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:scarb2c
gene id: 42514:scarb2c
uniprot id: A0A3B4BK39
names: Similarity
messages: Belongs to the CD36 family.

42514:ccr6a
gene id: 42514:ccr6a
uniprot id: A0A3B4CUT3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108426118
gene id: 42514:LOC108426118
uniprot id: A0A3B4CMQ3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:si:ch211-117c19.1
gene id: 42514:si:ch211-117c19.1
uniprot id: A0A3B4DGD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

42514:cd79a
gene id: 42514:cd79a
uniprot id: A0A3B4D8S4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:sema6ba
gene id: 42514:sema6ba
uniprot id: A0A3B4C1K3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:caly
gene id: 42514:caly
uniprot id: A0A3B4E3P2
names: Similarity
messages: Belongs to the NSG family.

42514:gpr156
gene id: 42514:gpr156
uniprot id: A0A3B4CVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:atxn2
gene id: 42514:atxn2
uniprot id: A0A3B4DQF9
names: Similarity
messages: Belongs to the ataxin-2 family.

42514:nr4a2a
gene id: 42514:nr4a2a
uniprot id: A0A3B4CHQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:thbs1b
gene id: 42514:thbs1b
uniprot id: A0A3B4D0C0
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:c12h3orf70
gene id: 42514:c12h3orf70
uniprot id: A0A3B4DS34
names: Similarity
messages: Belongs to the UPF0524 family.

42514:stom
gene id: 42514:stom
uniprot id: A0A3B4EFE1
uniprot id: A0A3B4EGX9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

42514:fgf12a
gene id: 42514:fgf12a
uniprot id: A0A3B4DEU7
uniprot id: A0A3B4DFA5
uniprot id: A0A3B4EPM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

42514:tac1
gene id: 42514:tac1
uniprot id: A0A3B4CGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

42514:cmbl
gene id: 42514:cmbl
uniprot id: A0A3B4CJY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

42514:mdh2
gene id: 42514:mdh2
uniprot id: A0A3B4CE36
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

42514:b9d2
gene id: 42514:b9d2
uniprot id: A0A3B4CGX9
names: Subcellular Location Annotation
messages: cilium basal body

42514:atp5l
gene id: 42514:atp5l
uniprot id: A0A3B4C4N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

42514:cdkn1d
gene id: 42514:cdkn1d
uniprot id: A0A3B4BQ78
names: Similarity
messages: Belongs to the CDI family.

42514:slc6a17
gene id: 42514:slc6a17
uniprot id: A0A3B4BPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:bxdc2
gene id: 42514:bxdc2
uniprot id: A0A3B4DQX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

42514:LOC108429431
gene id: 42514:LOC108429431
uniprot id: A0A3B4DWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: spindle pole

42514:tnfsf11
gene id: 42514:tnfsf11
uniprot id: A0A3B4CI43
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:tefb
gene id: 42514:tefb
uniprot id: A0A3B4C9I8
uniprot id: A0A3B4CCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

42514:kif4
gene id: 42514:kif4
uniprot id: A0A3B4D7J8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:LOC108425743
gene id: 42514:LOC108425743
uniprot id: A0A3B4C7Y0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:sfxn5a
gene id: 42514:sfxn5a
uniprot id: A0A3B4E7R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

42514:nkiras2
gene id: 42514:nkiras2
uniprot id: A0A3B4DDR3
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

42514:cxcr3.2
gene id: 42514:cxcr3.2
uniprot id: A0A3B4E9N9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:fbp2
gene id: 42514:fbp2
uniprot id: A0A3B4CBZ5
names: Similarity
messages: Belongs to the FBPase class 1 family.

42514:kif11
gene id: 42514:kif11
uniprot id: A0A3B4DB64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
messages: spindle pole

42514:zdhhc14
gene id: 42514:zdhhc14
uniprot id: A0A3B4D574
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:atl3
gene id: 42514:atl3
uniprot id: A0A3B4CSS9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

42514:LOC108423446
gene id: 42514:LOC108423446
uniprot id: A0A3B4C4U3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:emg1
gene id: 42514:emg1
uniprot id: A0A3B4CU39
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

42514:nudt21
gene id: 42514:nudt21
uniprot id: A0A3B4CJ37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

42514:pmepa1
gene id: 42514:pmepa1
uniprot id: A0A3B4C2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

42514:rsad2
gene id: 42514:rsad2
uniprot id: A0A3B4E5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RSAD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:pth2ra
gene id: 42514:pth2ra
uniprot id: A0A3B4EJA3
names: Subcellular Location Annotation
messages: Membrane

42514:nipsnap2
gene id: 42514:nipsnap2
uniprot id: A0A3B4DFV4
names: Similarity
messages: Belongs to the NipSnap family.

42514:mark3b
gene id: 42514:mark3b
uniprot id: A0A3B4CML4
uniprot id: A0A3B4E3D4
uniprot id: A0A3B4E5V1
uniprot id: A0A3B4E5V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

42514:elac2
gene id: 42514:elac2
uniprot id: A0A3B4E7J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Z family.
messages: mitochondrion nucleoid

42514:LOC108434931
gene id: 42514:LOC108434931
uniprot id: A0A3B4ERN6
names: Subcellular Location Annotation
messages: Membrane

42514:snd1
gene id: 42514:snd1
uniprot id: A0A3B4DMW7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

42514:gas6
gene id: 42514:gas6
uniprot id: A0A3B4DQJ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108412648
gene id: 42514:LOC108412648
uniprot id: A0A3B4EKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

42514:adi1
gene id: 42514:adi1
uniprot id: A0A3B4C0X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

42514:LOC108440224
gene id: 42514:LOC108440224
uniprot id: A0A3B4C718
names: Similarity
messages: Belongs to the globin family.

42514:tacr1b
gene id: 42514:tacr1b
uniprot id: A0A3B4BV91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:en2a
gene id: 42514:en2a
uniprot id: A0A3B4CMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

42514:lbr
gene id: 42514:lbr
uniprot id: A0A3B4DV73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

42514:aspdh
gene id: 42514:aspdh
uniprot id: A0A3B4C1F6
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.

42514:timeless
gene id: 42514:timeless
uniprot id: A0A3B4BST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

42514:paf1
gene id: 42514:paf1
uniprot id: A0A3B4CDV6
names: Similarity
messages: Belongs to the PAF1 family.

42514:sigmar1
gene id: 42514:sigmar1
uniprot id: A0A3B4EJB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle

42514:s1pr2
gene id: 42514:s1pr2
uniprot id: A0A3B4CL20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:alox5a
gene id: 42514:alox5a
uniprot id: A0A3B4DA59
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:lin9
gene id: 42514:lin9
uniprot id: A0A3B4C766
names: Similarity
messages: Belongs to the lin-9 family.

42514:LOC108427800
gene id: 42514:LOC108427800
uniprot id: A0A3B4CZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

42514:LOC108437647
gene id: 42514:LOC108437647
uniprot id: A0A3B4BXP0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:tgfb1b
gene id: 42514:tgfb1b
uniprot id: A0A3B4CKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

42514:LOC108427501
gene id: 42514:LOC108427501
uniprot id: A0A3B4DY87
names: Subcellular Location Annotation
messages: interphotoreceptor matrix

42514:upf2
gene id: 42514:upf2
uniprot id: A0A3B4DP04
names: Subcellular Location Annotation
messages: Cytoplasm

42514:zfp36l2
gene id: 42514:zfp36l2
uniprot id: A0A3B4BXK9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

42514:otud7a
gene id: 42514:otud7a
uniprot id: A0A3B4DUD4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:med22
gene id: 42514:med22
uniprot id: A0A3B4ENI3
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

42514:tmcc1a
gene id: 42514:tmcc1a
uniprot id: A0A3B4BKB3
uniprot id: A0A3B4BP45
uniprot id: A0A3B4DIS0
names: Similarity
messages: Belongs to the TEX28 family.

42514:kdelr2a
gene id: 42514:kdelr2a
uniprot id: A0A3B4EJ58
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:serpine2
gene id: 42514:serpine2
uniprot id: A0A3B4D033
names: Similarity
messages: Belongs to the serpin family.

42514:LOC108425006
gene id: 42514:LOC108425006
uniprot id: A0A3B4CRI6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

42514:LOC108436944
gene id: 42514:LOC108436944
uniprot id: A0A3B4DZI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

42514:st8sia6
gene id: 42514:st8sia6
uniprot id: A0A3B4DRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:dop1b
gene id: 42514:dop1b
uniprot id: A0A3B4BNR0
names: Similarity
messages: Belongs to the dopey family.

42514:lpcat1
gene id: 42514:lpcat1
uniprot id: A0A3B4DH39
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:washc5
gene id: 42514:washc5
uniprot id: A0A3B4E2H1
names: Similarity
messages: Belongs to the strumpellin family.

42514:srprb
gene id: 42514:srprb
uniprot id: A0A3B4DNP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:triqk
gene id: 42514:triqk
uniprot id: A0A3B4C462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:snap25a
gene id: 42514:snap25a
uniprot id: A0A3B4EMM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

42514:pdrg1
gene id: 42514:pdrg1
uniprot id: A0A3B4C9M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

42514:LOC108414487
gene id: 42514:LOC108414487
uniprot id: A0A3B4D6R6
names: Similarity
messages: Belongs to the NDK family.

42514:pnkd
gene id: 42514:pnkd
uniprot id: A0A3B4BR82
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

42514:fam174c
gene id: 42514:fam174c
uniprot id: A0A3B4EGL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

42514:LOC108436144
gene id: 42514:LOC108436144
uniprot id: A0A3B4EC06
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:gjb7
gene id: 42514:gjb7
uniprot id: A0A3B4DD62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:kdm6al
gene id: 42514:kdm6al
uniprot id: A0A3B4BZR1
uniprot id: A0A3B4DR34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

42514:ptch2
gene id: 42514:ptch2
uniprot id: A0A3B4DLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

42514:tmem121b
gene id: 42514:tmem121b
uniprot id: A0A3B4BRN9
names: Similarity
messages: Belongs to the TMEM121 family.

42514:unc5db
gene id: 42514:unc5db
uniprot id: A0A3B4BWT2
uniprot id: A0A3B4BWV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

42514:LOC108432842
gene id: 42514:LOC108432842
uniprot id: A0A3B4D2Q6
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

42514:LOC108427628
gene id: 42514:LOC108427628
uniprot id: A0A3B4DG28
names: Subcellular Location Annotation
messages: Nucleus

42514:ptprna
gene id: 42514:ptprna
uniprot id: A0A3B4DUR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

42514:plcd1a
gene id: 42514:plcd1a
uniprot id: A0A3B4CRH2
uniprot id: A0A3B4E8I4
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

42514:alpl
gene id: 42514:alpl
uniprot id: A0A3B4CSJ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

42514:slc43a3b
gene id: 42514:slc43a3b
uniprot id: A0A3B4EEC2
names: Subcellular Location Annotation
messages: Membrane

42514:opn7d
gene id: 42514:opn7d
uniprot id: A0A3B4E3X8
names: Subcellular Location Annotation
messages: Membrane

42514:mcm6l
gene id: 42514:mcm6l
uniprot id: A0A3B4C5Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

42514:nup98
gene id: 42514:nup98
uniprot id: A0A3B4DYL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

42514:LOC108417198
gene id: 42514:LOC108417198
uniprot id: A0A3B4D896
uniprot id: A0A3B4EHF4
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

42514:slc35d1a
gene id: 42514:slc35d1a
uniprot id: A0A3B4DS94
names: Subcellular Location Annotation
messages: Membrane

42514:abl1
gene id: 42514:abl1
uniprot id: A0A3B4DZQ6
uniprot id: A0A3B4E002
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:chchd6a
gene id: 42514:chchd6a
uniprot id: A0A3B4D0X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Membrane
messages: Mitochondrion inner membrane

42514:bckdha
gene id: 42514:bckdha
uniprot id: A0A3B4ES62
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

42514:rbks
gene id: 42514:rbks
uniprot id: A0A3B4C070
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

42514:hmgb1a
gene id: 42514:hmgb1a
uniprot id: A0A3B4DSI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

42514:ext2
gene id: 42514:ext2
uniprot id: A0A3B4CE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

42514:psmb2
gene id: 42514:psmb2
uniprot id: A0A3B4EFY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

42514:nrn1a
gene id: 42514:nrn1a
uniprot id: A0A3B4DIC0
names: Similarity
messages: Belongs to the neuritin family.

42514:rnmt
gene id: 42514:rnmt
uniprot id: A0A3B4D8D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus

42514:plod1a
gene id: 42514:plod1a
uniprot id: A0A3B4DBN8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

42514:actr2b
gene id: 42514:actr2b
uniprot id: A0A3B4DUC2
names: Similarity
messages: Belongs to the actin family.

42514:zgc:158270
gene id: 42514:zgc:158270
uniprot id: A0A3B4C704
uniprot id: A0A3B4C8C8
uniprot id: A0A3B4DXG3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

42514:LOC108414383
gene id: 42514:LOC108414383
uniprot id: A0A3B4BMZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

42514:extl2
gene id: 42514:extl2
uniprot id: A0A3B4EJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

42514:naa10
gene id: 42514:naa10
uniprot id: A0A3B4E760
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

42514:ppm1g
gene id: 42514:ppm1g
uniprot id: A0A3B4C2X8
names: Similarity
messages: Belongs to the PP2C family.

42514:aqp11
gene id: 42514:aqp11
uniprot id: A0A3B4CKK7
uniprot id: A0A3B4E649
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108437088
gene id: 42514:LOC108437088
uniprot id: A0A3B4C096
names: Similarity
messages: Belongs to the TGF-beta family.

42514:tmem107
gene id: 42514:tmem107
uniprot id: A0A3B4DVW8
names: Subcellular Location Annotation
messages: Membrane

42514:atrnl1b
gene id: 42514:atrnl1b
uniprot id: A0A3B4DF62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:mrps7
gene id: 42514:mrps7
uniprot id: A0A3B4CLI6
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

42514:mapkapk2b
gene id: 42514:mapkapk2b
uniprot id: A0A3B4DH78
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:sept6
gene id: 42514:sept6
uniprot id: A0A3B4E9B5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

42514:LOC108434578
gene id: 42514:LOC108434578
uniprot id: A0A3B4CTZ0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:kif5bb
gene id: 42514:kif5bb
uniprot id: A0A3B4BTN1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:gemin2
gene id: 42514:gemin2
uniprot id: A0A3B4CJU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

42514:LOC108427823
gene id: 42514:LOC108427823
uniprot id: A0A3B4CXA9
names: Similarity
messages: Belongs to the NKAP family.

42514:tcf7l2
gene id: 42514:tcf7l2
uniprot id: A0A3B4DC06
uniprot id: A0A3B4ENU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

42514:LOC108430740
gene id: 42514:LOC108430740
uniprot id: A0A3B4CKP8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:si:dkey-97m3.1
gene id: 42514:si:dkey-97m3.1
uniprot id: A0A3B4D2D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

42514:ext1a
gene id: 42514:ext1a
uniprot id: A0A3B4C3K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

42514:mlh1
gene id: 42514:mlh1
uniprot id: A0A3B4CLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

42514:ercc2
gene id: 42514:ercc2
uniprot id: A0A3B4DQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

42514:hs6st3b
gene id: 42514:hs6st3b
uniprot id: A0A3B4D8L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

42514:vgll2a
gene id: 42514:vgll2a
uniprot id: A0A3B4CBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

42514:LOC108440497
gene id: 42514:LOC108440497
uniprot id: A0A3B4EJI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:sin3ab
gene id: 42514:sin3ab
uniprot id: A0A3B4E0A0
names: Subcellular Location Annotation
messages: Nucleus

42514:slc25a19
gene id: 42514:slc25a19
uniprot id: A0A3B4CNL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:LOC108411357
gene id: 42514:LOC108411357
uniprot id: A0A3B4BNB5
names: Similarity
messages: Belongs to the CLCR family.

42514:lmf2b
gene id: 42514:lmf2b
uniprot id: A0A3B4BWC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

42514:krt1-c5
gene id: 42514:krt1-c5
uniprot id: A0A3B4EKF0
names: Similarity
messages: Belongs to the intermediate filament family.

42514:pfkmb
gene id: 42514:pfkmb
uniprot id: A0A3B4DZB5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ctsba
gene id: 42514:ctsba
uniprot id: A0A3B4D6Z1
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:LOC108415251
gene id: 42514:LOC108415251
uniprot id: A0A3B4DKW3
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:vkorc1l1
gene id: 42514:vkorc1l1
uniprot id: A0A3B4CQ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:si:dkey-185m8.2
gene id: 42514:si:dkey-185m8.2
uniprot id: A0A3B4DAZ7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:galr1a
gene id: 42514:galr1a
uniprot id: A0A3B4CHM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:LOC108443670
gene id: 42514:LOC108443670
uniprot id: A0A3B4C145
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:zdhhc23b
gene id: 42514:zdhhc23b
uniprot id: A0A3B4CV42
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:rpl35a
gene id: 42514:rpl35a
uniprot id: A0A3B4E9E9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

42514:pik3ip1
gene id: 42514:pik3ip1
uniprot id: A0A3B4DTC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108443227
gene id: 42514:LOC108443227
uniprot id: A0A3B4DIW9
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

42514:sfxn1
gene id: 42514:sfxn1
uniprot id: A0A3B4D1T5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

42514:actb2
gene id: 42514:actb2
uniprot id: A0A3B4CWN6
names: Similarity
messages: Belongs to the actin family.

42514:LOC108414495
gene id: 42514:LOC108414495
uniprot id: A0A3B4D5V2
names: Subcellular Location Annotation
messages: Membrane

42514:kctd10
gene id: 42514:kctd10
uniprot id: A0A3B4CIV0
names: Similarity
messages: Belongs to the BACURD family.

42514:LOC108431043
gene id: 42514:LOC108431043
uniprot id: A0A3B4BQV5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:malb
gene id: 42514:malb
uniprot id: A0A3B4DTH8
names: Subcellular Location Annotation
messages: Membrane

42514:eef1a1b
gene id: 42514:eef1a1b
uniprot id: A0A3B4DNG9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

42514:LOC108442020
gene id: 42514:LOC108442020
uniprot id: A0A3B4BUA2
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:lim2.4
gene id: 42514:lim2.4
uniprot id: A0A3B4DLT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:hdhd2
gene id: 42514:hdhd2
uniprot id: A0A3B4EKJ1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

42514:hoxb1a
gene id: 42514:hoxb1a
uniprot id: A0A3B4CD95
names: Subcellular Location Annotation
messages: Nucleus

42514:crabp1b
gene id: 42514:crabp1b
uniprot id: A0A3B4E0E7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:LOC108436554
gene id: 42514:LOC108436554
uniprot id: A0A3B4BPG3
names: Subcellular Location Annotation
messages: Nucleus

42514:taz
gene id: 42514:taz
uniprot id: A0A3B4EA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

42514:cyhr1
gene id: 42514:cyhr1
uniprot id: A0A3B4EK26
names: Similarity
messages: Belongs to the ZFTRAF1 family.

42514:zeb2a
gene id: 42514:zeb2a
uniprot id: A0A3B4DVW7
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

42514:LOC108441433
gene id: 42514:LOC108441433
uniprot id: A0A3B4C1W7
uniprot id: A0A3B4C4K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus

42514:tcea3
gene id: 42514:tcea3
uniprot id: A0A3B4CVC8
uniprot id: A0A3B4CZ48
uniprot id: A0A3B4CZP0
uniprot id: A0A3B4EAC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

42514:slc35b3
gene id: 42514:slc35b3
uniprot id: A0A3B4D643
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

42514:ptges3l
gene id: 42514:ptges3l
uniprot id: A0A3B4DI52
names: Similarity
messages: Belongs to the p23/wos2 family.

42514:prorp
gene id: 42514:prorp
uniprot id: A0A3B4CLD1
uniprot id: A0A3B4CLD6
uniprot id: A0A3B4E3M1
names: Similarity
messages: Belongs to the PPR family. P subfamily.

42514:e2f3
gene id: 42514:e2f3
uniprot id: A0A3B4EPH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

42514:ptgs1
gene id: 42514:ptgs1
uniprot id: A0A3B4D9Z7
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ndufab1a
gene id: 42514:ndufab1a
uniprot id: A0A3B4E0F5
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

42514:afmid
gene id: 42514:afmid
uniprot id: A0A3B4D1N6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

42514:LOC108412955
gene id: 42514:LOC108412955
uniprot id: A0A3B4CD72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

42514:jag1b
gene id: 42514:jag1b
uniprot id: A0A3B4E235
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

42514:polrmt
gene id: 42514:polrmt
uniprot id: A0A3B4CTI5
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

42514:fscn1a
gene id: 42514:fscn1a
uniprot id: A0A3B4D0A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

42514:cept1b
gene id: 42514:cept1b
uniprot id: A0A3B4C9T1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

42514:sars2
gene id: 42514:sars2
uniprot id: A0A3B4D436
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

42514:LOC108431527
gene id: 42514:LOC108431527
uniprot id: A0A3B4BRB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:pdpk1b
gene id: 42514:pdpk1b
uniprot id: A0A3B4DW50
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

42514:LOC108415300
gene id: 42514:LOC108415300
uniprot id: A0A3B4BQK8
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:rasgrp2
gene id: 42514:rasgrp2
uniprot id: A0A3B4C6A3
names: Similarity
messages: Belongs to the RASGRP family.

42514:metap2b
gene id: 42514:metap2b
uniprot id: A0A3B4DHE8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

42514:csnk1e
gene id: 42514:csnk1e
uniprot id: A0A3B4DSL5
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:cd82b
gene id: 42514:cd82b
uniprot id: A0A3B4EFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:pih1d1
gene id: 42514:pih1d1
uniprot id: A0A3B4E6F2
names: Similarity
messages: Belongs to the PIH1 family.

42514:dclre1c
gene id: 42514:dclre1c
uniprot id: A0A3B4DPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

42514:ano5b
gene id: 42514:ano5b
uniprot id: A0A3B4CDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

42514:cers2a
gene id: 42514:cers2a
uniprot id: A0A3B4CLC3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

42514:scn12aa
gene id: 42514:scn12aa
uniprot id: A0A3B4D3E4
uniprot id: A0A3B4EGX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

42514:LOC108424757
gene id: 42514:LOC108424757
uniprot id: A0A3B4ERF9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:hhipl1
gene id: 42514:hhipl1
uniprot id: A0A3B4CWE8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:cdk9
gene id: 42514:cdk9
uniprot id: A0A3B4DJ36
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:rtcb
gene id: 42514:rtcb
uniprot id: A0A3B4DMD0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

42514:erlec1
gene id: 42514:erlec1
uniprot id: A0A3B4DCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum lumen
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

42514:usp30
gene id: 42514:usp30
uniprot id: A0A3B4BVN4
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:pah
gene id: 42514:pah
uniprot id: A0A3B4CED1
uniprot id: A0A3B4CED6
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

42514:gpat3
gene id: 42514:gpat3
uniprot id: A0A3B4BTC7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:serpinh2
gene id: 42514:serpinh2
uniprot id: A0A3B4D4J8
names: Similarity
messages: Belongs to the serpin family.

42514:scrn3
gene id: 42514:scrn3
uniprot id: A0A3B4CS05
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

42514:llgl1
gene id: 42514:llgl1
uniprot id: A0A3B4EEA0
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

42514:sgsh
gene id: 42514:sgsh
uniprot id: A0A3B4EED8
names: Similarity
messages: Belongs to the sulfatase family.

42514:trim33l
gene id: 42514:trim33l
uniprot id: A0A3B4BRM6
names: Subcellular Location Annotation
messages: Cytoplasm

42514:siah2l
gene id: 42514:siah2l
uniprot id: A0A3B4CFI2
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

42514:LOC108427228
gene id: 42514:LOC108427228
uniprot id: A0A3B4CY28
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

42514:fam102aa
gene id: 42514:fam102aa
uniprot id: A0A3B4DJF1
names: Similarity
messages: Belongs to the EEIG family.

42514:pias4b
gene id: 42514:pias4b
uniprot id: A0A3B4DC22
names: Similarity
messages: Belongs to the PIAS family.

42514:ppip5k2
gene id: 42514:ppip5k2
uniprot id: A0A3B4EB57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

42514:prkg3
gene id: 42514:prkg3
uniprot id: A0A3B4E7X9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

42514:zgc:158291
gene id: 42514:zgc:158291
uniprot id: A0A3B4CHW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

42514:mrpl24
gene id: 42514:mrpl24
uniprot id: A0A3B4BS58
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

42514:LOC108438613
gene id: 42514:LOC108438613
uniprot id: A0A3B4C8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

42514:snrpd2
gene id: 42514:snrpd2
uniprot id: A0A3B4D7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

42514:LOC108434041
gene id: 42514:LOC108434041
uniprot id: A0A3B4CL11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:sparc
gene id: 42514:sparc
uniprot id: A0A3B4D543
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

42514:atp2a2a
gene id: 42514:atp2a2a
uniprot id: A0A3B4D2X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

42514:mos
gene id: 42514:mos
uniprot id: A0A3B4BTB8
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:coq3
gene id: 42514:coq3
uniprot id: A0A3B4E4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

42514:agxta
gene id: 42514:agxta
uniprot id: A0A3B4EQP5
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

42514:adhfe1
gene id: 42514:adhfe1
uniprot id: A0A3B4E9K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

42514:skp1
gene id: 42514:skp1
uniprot id: A0A3B4CFK7
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.

42514:tubb4b
gene id: 42514:tubb4b
uniprot id: A0A3B4DBV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:tnfrsf21
gene id: 42514:tnfrsf21
uniprot id: A0A3B4CIQ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:antxr1c
gene id: 42514:antxr1c
uniprot id: A0A3B4EEQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

42514:apc
gene id: 42514:apc
uniprot id: A0A3B4CPI9
uniprot id: A0A3B4E7D2
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

42514:hoxd9a
gene id: 42514:hoxd9a
uniprot id: A0A3B4CWU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:chpfb
gene id: 42514:chpfb
uniprot id: A0A3B4EBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

42514:boka
gene id: 42514:boka
uniprot id: A0A3B4EP33
names: Similarity
messages: Belongs to the Bcl-2 family.

42514:psmd4a
gene id: 42514:psmd4a
uniprot id: A0A3B4BQ20
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

42514:sar1aa
gene id: 42514:sar1aa
uniprot id: A0A3B4BR37
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

42514:lamp2
gene id: 42514:lamp2
uniprot id: A0A3B4CXJ9
uniprot id: A0A3B4E8R4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

42514:gprc5ba
gene id: 42514:gprc5ba
uniprot id: A0A3B4D294
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:spon2b
gene id: 42514:spon2b
uniprot id: A0A3B4D040
names: Subcellular Location Annotation
messages: extracellular matrix

42514:stk38a
gene id: 42514:stk38a
uniprot id: A0A3B4CZB3
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:ppp2r5cb
gene id: 42514:ppp2r5cb
uniprot id: A0A3B4E9V4
uniprot id: A0A3B4EBK1
uniprot id: A0A3B4EBQ8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

42514:alkbh6
gene id: 42514:alkbh6
uniprot id: A0A3B4D2X1
names: Similarity
messages: Belongs to the alkB family.

42514:LOC108427783
gene id: 42514:LOC108427783
uniprot id: A0A3B4CZM2
uniprot id: A0A3B4EBR4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:man1b1b
gene id: 42514:man1b1b
uniprot id: A0A3B4EB63
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

42514:pdgfc
gene id: 42514:pdgfc
uniprot id: A0A3B4CRC6
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108440227
gene id: 42514:LOC108440227
uniprot id: A0A3B4DRH1
names: Similarity
messages: Belongs to the globin family.

42514:tlr1
gene id: 42514:tlr1
uniprot id: A0A3B4D0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

42514:h3f3c
gene id: 42514:h3f3c
uniprot id: A0A3B4BZQ6
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:coro2a
gene id: 42514:coro2a
uniprot id: A0A3B4D754
names: Similarity
messages: Belongs to the WD repeat coronin family.

42514:LOC108411646
gene id: 42514:LOC108411646
uniprot id: A0A3B4EC40
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

42514:isl2b
gene id: 42514:isl2b
uniprot id: A0A3B4DYU5
names: Subcellular Location Annotation
messages: Nucleus

42514:npb
gene id: 42514:npb
uniprot id: A0A3B4EEG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

42514:gadd45bb
gene id: 42514:gadd45bb
uniprot id: A0A3B4CC44
names: Similarity
messages: Belongs to the GADD45 family.

42514:slc35a3a
gene id: 42514:slc35a3a
uniprot id: A0A3B4D6B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:c9
gene id: 42514:c9
uniprot id: A0A3B4D296
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

42514:ube2l3b
gene id: 42514:ube2l3b
uniprot id: A0A3B4EBB3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:ipo7
gene id: 42514:ipo7
uniprot id: A0A3B4D9I9
names: Subcellular Location Annotation
messages: Cytoplasm

42514:si:ch211-195d17.2
gene id: 42514:si:ch211-195d17.2
uniprot id: A0A3B4EF71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

42514:cadm2b
gene id: 42514:cadm2b
uniprot id: A0A3B4BVG1
uniprot id: A0A3B4BYM3
uniprot id: A0A3B4BYR9
names: Similarity
messages: Belongs to the nectin family.

42514:mknk2a
gene id: 42514:mknk2a
uniprot id: A0A3B4DKM5
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:slc39a9
gene id: 42514:slc39a9
uniprot id: A0A3B4BZG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

42514:sf3b3
gene id: 42514:sf3b3
uniprot id: A0A3B4CD56
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108430767
gene id: 42514:LOC108430767
uniprot id: A0A3B4CIS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

42514:psmb11a
gene id: 42514:psmb11a
uniprot id: A0A3B4EDI2
names: Subcellular Location Annotation
messages: Nucleus

42514:si:ch211-184m13.4
gene id: 42514:si:ch211-184m13.4
uniprot id: A0A3B4CZ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:slc6a16a
gene id: 42514:slc6a16a
uniprot id: A0A3B4C361
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:dbndd1
gene id: 42514:dbndd1
uniprot id: A0A3B4E3T9
names: Similarity
messages: Belongs to the dysbindin family.

42514:azin1b
gene id: 42514:azin1b
uniprot id: A0A3B4C0C6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

42514:agla
gene id: 42514:agla
uniprot id: A0A3B4DKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

42514:orai1b
gene id: 42514:orai1b
uniprot id: A0A3B4CJ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

42514:LOC108430779
gene id: 42514:LOC108430779
uniprot id: A0A3B4BUS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:xgb
gene id: 42514:xgb
uniprot id: A0A3B4CTW6
names: Similarity
messages: Belongs to the globin family.

42514:rab38a
gene id: 42514:rab38a
uniprot id: A0A3B4D8Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

42514:txlna
gene id: 42514:txlna
uniprot id: A0A3B4EPQ7
names: Similarity
messages: Belongs to the taxilin family.

42514:atp5if1a
gene id: 42514:atp5if1a
uniprot id: A0A3B4CX78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

42514:slc7a2
gene id: 42514:slc7a2
uniprot id: A0A3B4CQF0
uniprot id: A0A3B4CST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

42514:adgra3
gene id: 42514:adgra3
uniprot id: A0A3B4BWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

42514:mab21l2
gene id: 42514:mab21l2
uniprot id: A0A3B4E9J6
names: Similarity
messages: Belongs to the mab-21 family.

42514:ndufs6
gene id: 42514:ndufs6
uniprot id: A0A3B4DFG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

42514:LOC108433744
gene id: 42514:LOC108433744
uniprot id: A0A3B4DP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

42514:LOC108433657
gene id: 42514:LOC108433657
uniprot id: A0A3B4C4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

42514:LOC108435795
gene id: 42514:LOC108435795
uniprot id: A0A3B4CG01
names: Similarity
messages: Belongs to the peptidase C2 family.

42514:gde1
gene id: 42514:gde1
uniprot id: A0A3B4E594
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

42514:cct7
gene id: 42514:cct7
uniprot id: A0A3B4BXT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

42514:acoxl
gene id: 42514:acoxl
uniprot id: A0A3B4BSM3
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

42514:tlcd3bb
gene id: 42514:tlcd3bb
uniprot id: A0A3B4D9T0
names: Subcellular Location Annotation
messages: Membrane

42514:acvrl1
gene id: 42514:acvrl1
uniprot id: A0A3B4EH50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:LOC108441353
gene id: 42514:LOC108441353
uniprot id: A0A3B4DZZ2
names: Subcellular Location Annotation
messages: Membrane

42514:si:ch211-30b16.2
gene id: 42514:si:ch211-30b16.2
uniprot id: A0A3B4CT53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:rnf170
gene id: 42514:rnf170
uniprot id: A0A3B4C6L0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108425338
gene id: 42514:LOC108425338
uniprot id: A0A3B4BQF7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

42514:odc1
gene id: 42514:odc1
uniprot id: A0A3B4BZP8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

42514:clic2
gene id: 42514:clic2
uniprot id: A0A3B4CTS3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

42514:fbxl5
gene id: 42514:fbxl5
uniprot id: A0A3B4EIT2
names: Subcellular Location Annotation
messages: perinuclear region

42514:foxn3
gene id: 42514:foxn3
uniprot id: A0A3B4D905
names: Function
names: Subcellular Location Annotation
messages: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).
messages: Nucleus

42514:sema7a
gene id: 42514:sema7a
uniprot id: A0A3B4C7T4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ccbe1
gene id: 42514:ccbe1
uniprot id: A0A3B4EEX6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:aatf
gene id: 42514:aatf
uniprot id: A0A3B4CBF4
names: Similarity
messages: Belongs to the AATF family.

42514:hpse
gene id: 42514:hpse
uniprot id: A0A3B4BWW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

42514:znf703
gene id: 42514:znf703
uniprot id: A0A3B4BPL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

42514:LOC108430449
gene id: 42514:LOC108430449
uniprot id: A0A3B4EQ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

42514:LOC108425342
gene id: 42514:LOC108425342
uniprot id: A0A3B4DI82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:gatad2b
gene id: 42514:gatad2b
uniprot id: A0A3B4ENB0
names: Subcellular Location Annotation
messages: Nucleus

42514:serinc4
gene id: 42514:serinc4
uniprot id: A0A3B4CXI6
uniprot id: A0A3B4EAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

42514:LOC108411899
gene id: 42514:LOC108411899
uniprot id: A0A3B4C6T9
names: Similarity
messages: Belongs to the SEC6 family.

42514:etfdh
gene id: 42514:etfdh
uniprot id: A0A3B4EP56
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

42514:unm hu7910
gene id: 42514:unm_hu7910
uniprot id: A0A3B4E806
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

42514:pfn2l
gene id: 42514:pfn2l
uniprot id: A0A3B4CEY2
names: Similarity
messages: Belongs to the profilin family.

42514:b4galt4
gene id: 42514:b4galt4
uniprot id: A0A3B4BNY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

42514:tubb4bl
gene id: 42514:tubb4bl
uniprot id: A0A3B4CEQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:LOC108425592
gene id: 42514:LOC108425592
uniprot id: A0A3B4CK22
uniprot id: A0A3B4CK40
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:slc1a9
gene id: 42514:slc1a9
uniprot id: A0A3B4DGC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

42514:LOC108442743
gene id: 42514:LOC108442743
uniprot id: A0A3B4DGQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:sostdc1b
gene id: 42514:sostdc1b
uniprot id: A0A3B4BUU5
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:si:ch211-149b19.3
gene id: 42514:si:ch211-149b19.3
uniprot id: A0A3B4BQL4
names: Similarity
messages: Belongs to the PP2C family.

42514:pde6c
gene id: 42514:pde6c
uniprot id: A0A3B4C7Y8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:mmp17a
gene id: 42514:mmp17a
uniprot id: A0A3B4EIB8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

42514:LOC108413001
gene id: 42514:LOC108413001
uniprot id: A0A3B4DY23
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:lmnl3
gene id: 42514:lmnl3
uniprot id: A0A3B4CH96
uniprot id: A0A3B4E0T1
names: Similarity
messages: Belongs to the intermediate filament family.

42514:rtn1b
gene id: 42514:rtn1b
uniprot id: A0A3B4D9V8
uniprot id: A0A3B4EKB8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:rps26l
gene id: 42514:rps26l
uniprot id: A0A3B4DP86
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

42514:sv2bb
gene id: 42514:sv2bb
uniprot id: A0A3B4DGD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

42514:LOC108433637
gene id: 42514:LOC108433637
uniprot id: A0A3B4DY61
names: Subcellular Location Annotation
messages: Membrane

42514:notum1b
gene id: 42514:notum1b
uniprot id: A0A3B4DHJ8
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

42514:nmt1b
gene id: 42514:nmt1b
uniprot id: A0A3B4D5P5
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

42514:ptgs2b
gene id: 42514:ptgs2b
uniprot id: A0A3B4E4K8
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:oprk1
gene id: 42514:oprk1
uniprot id: A0A3B4E712
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:pth3r
gene id: 42514:pth3r
uniprot id: A0A3B4BTY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

42514:ppat
gene id: 42514:ppat
uniprot id: A0A3B4DJJ0
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

42514:ccr9a
gene id: 42514:ccr9a
uniprot id: A0A3B4DKP5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:phactr4b
gene id: 42514:phactr4b
uniprot id: A0A3B4CXV5
uniprot id: A0A3B4CY03
uniprot id: A0A3B4EEA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

42514:zmp:0000000660
gene id: 42514:zmp:0000000660
uniprot id: A0A3B4BZH0
uniprot id: A0A3B4DT72
names: Subcellular Location Annotation
messages: Cytoplasm

42514:tmco1
gene id: 42514:tmco1
uniprot id: A0A3B4EB99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:rad23b
gene id: 42514:rad23b
uniprot id: A0A3B4BWQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

42514:blm
gene id: 42514:blm
uniprot id: A0A3B4C4J8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

42514:c16h18orf25
gene id: 42514:c16h18orf25
uniprot id: A0A3B4CLZ3
uniprot id: A0A3B4E5H4
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108429511
gene id: 42514:LOC108429511
uniprot id: A0A3B4CU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Late endosome membrane
messages: Membrane

42514:LOC108429393
gene id: 42514:LOC108429393
uniprot id: A0A3B4EJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:orc3
gene id: 42514:orc3
uniprot id: A0A3B4BPJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

42514:nfyba
gene id: 42514:nfyba
uniprot id: A0A3B4DRG5
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

42514:cmc1
gene id: 42514:cmc1
uniprot id: A0A3B4EMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

42514:ccnh
gene id: 42514:ccnh
uniprot id: A0A3B4D577
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

42514:lsr
gene id: 42514:lsr
uniprot id: A0A3B4BUH7
uniprot id: A0A3B4BUS6
uniprot id: A0A3B4DML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

42514:LOC108425233
gene id: 42514:LOC108425233
uniprot id: A0A3B4BW95
uniprot id: A0A3B4DJS2
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:vegfab
gene id: 42514:vegfab
uniprot id: A0A3B4CR50
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

42514:adora2b
gene id: 42514:adora2b
uniprot id: A0A3B4E5N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:yeats2
gene id: 42514:yeats2
uniprot id: A0A3B4CVF9
names: Subcellular Location Annotation
messages: Nucleus

42514:vipr2
gene id: 42514:vipr2
uniprot id: A0A3B4DES2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

42514:cdk5rap1
gene id: 42514:cdk5rap1
uniprot id: A0A3B4CAM0
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

42514:slc17a9b
gene id: 42514:slc17a9b
uniprot id: A0A3B4CHN0
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108415433
gene id: 42514:LOC108415433
uniprot id: A0A3B4DH01
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108436499
gene id: 42514:LOC108436499
uniprot id: A0A3B4DKV1
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

42514:LOC108411143
gene id: 42514:LOC108411143
uniprot id: A0A3B4CDM3
names: Similarity
messages: Belongs to the dapper family.

42514:LOC108442076
gene id: 42514:LOC108442076
uniprot id: A0A3B4DFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:dhrs13a.3
gene id: 42514:dhrs13a.3
uniprot id: A0A3B4BVB6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:LOC108441221
gene id: 42514:LOC108441221
uniprot id: A0A3B4E6M1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:vsx2
gene id: 42514:vsx2
uniprot id: A0A3B4E9W6
names: Subcellular Location Annotation
messages: Nucleus

42514:kcnf1b
gene id: 42514:kcnf1b
uniprot id: A0A3B4DTG3
names: Subcellular Location Annotation
messages: Membrane

42514:lnpk
gene id: 42514:lnpk
uniprot id: A0A3B4C8Q6
uniprot id: A0A3B4DWH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

42514:six3b
gene id: 42514:six3b
uniprot id: A0A3B4DKQ4
names: Subcellular Location Annotation
messages: Nucleus

42514:erlin1
gene id: 42514:erlin1
uniprot id: A0A3B4CDE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Membrane

42514:limk1b
gene id: 42514:limk1b
uniprot id: A0A3B4E0N8
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

42514:zgc:114130
gene id: 42514:zgc:114130
uniprot id: A0A3B4CZR4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

42514:tram1
gene id: 42514:tram1
uniprot id: A0A3B4EEE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

42514:atp6v0a1b
gene id: 42514:atp6v0a1b
uniprot id: A0A3B4D8S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

42514:lim2.5
gene id: 42514:lim2.5
uniprot id: A0A3B4EE94
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:cnot3b
gene id: 42514:cnot3b
uniprot id: A0A3B4DAH0
uniprot id: A0A3B4DBM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Nucleus

42514:mat2b
gene id: 42514:mat2b
uniprot id: A0A3B4DDV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

42514:actl6a
gene id: 42514:actl6a
uniprot id: A0A3B4D973
names: Similarity
messages: Belongs to the actin family.

42514:ubl4a
gene id: 42514:ubl4a
uniprot id: A0A3B4EBE2
names: Subcellular Location Annotation
messages: cytosol

42514:myod1
gene id: 42514:myod1
uniprot id: A0A3B4ENT0
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

42514:psma6a
gene id: 42514:psma6a
uniprot id: A0A3B4CL96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

42514:LOC108436424
gene id: 42514:LOC108436424
uniprot id: A0A3B4BZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:mark2a
gene id: 42514:mark2a
uniprot id: A0A3B4C5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

42514:ddx3xb
gene id: 42514:ddx3xb
uniprot id: A0A3B4DQC6
uniprot id: A0A3B4DRD8
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:LOC108429948
gene id: 42514:LOC108429948
uniprot id: A0A3B4EIE1
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:stard9
gene id: 42514:stard9
uniprot id: A0A3B4E2C1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:LOC108442162
gene id: 42514:LOC108442162
uniprot id: A0A3B4DAA2
uniprot id: A0A3B4EMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOG/XMAP215 family.
messages: kinetochore

42514:cdh6
gene id: 42514:cdh6
uniprot id: A0A3B4EB94
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

42514:pde4bb
gene id: 42514:pde4bb
uniprot id: A0A3B4E5V0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:c1d
gene id: 42514:c1d
uniprot id: A0A3B4DC18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

42514:cdc5l
gene id: 42514:cdc5l
uniprot id: A0A3B4CPQ6
names: Similarity
messages: Belongs to the CEF1 family.

42514:synpr
gene id: 42514:synpr
uniprot id: A0A3B4CA62
uniprot id: A0A3B4CC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

42514:frrs1b
gene id: 42514:frrs1b
uniprot id: A0A3B4CW55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

42514:LOC108437148
gene id: 42514:LOC108437148
uniprot id: A0A3B4BT40
names: Similarity
messages: Belongs to the actin family.

42514:ergic1
gene id: 42514:ergic1
uniprot id: A0A3B4CNI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

42514:psmc2
gene id: 42514:psmc2
uniprot id: A0A3B4CG18
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:coq8aa
gene id: 42514:coq8aa
uniprot id: A0A3B4EQA0
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

42514:spata18
gene id: 42514:spata18
uniprot id: A0A3B4BYH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

42514:nudt1
gene id: 42514:nudt1
uniprot id: A0A3B4EB56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

42514:si:dkey-151g10.3
gene id: 42514:si:dkey-151g10.3
uniprot id: A0A3B4CQQ1
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

42514:LOC108443086
gene id: 42514:LOC108443086
uniprot id: A0A3B4C7V4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

42514:zufsp
gene id: 42514:zufsp
uniprot id: A0A3B4DWC5
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

42514:LOC108433632
gene id: 42514:LOC108433632
uniprot id: A0A3B4C800
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

42514:zgc:55461
gene id: 42514:zgc:55461
uniprot id: A0A3B4EFT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:heatr5b
gene id: 42514:heatr5b
uniprot id: A0A3B4DQ08
names: Similarity
messages: Belongs to the HEATR5 family.

42514:pex19
gene id: 42514:pex19
uniprot id: A0A3B4C1A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

42514:si:dkey-156n14.5
gene id: 42514:si:dkey-156n14.5
uniprot id: A0A3B4EN24
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:clptm1
gene id: 42514:clptm1
uniprot id: A0A3B4BWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

42514:aldh9a1b
gene id: 42514:aldh9a1b
uniprot id: A0A3B4CK27
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

42514:hnf4b
gene id: 42514:hnf4b
uniprot id: A0A3B4DZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:odr4
gene id: 42514:odr4
uniprot id: A0A3B4E8V4
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

42514:zdhhc15b
gene id: 42514:zdhhc15b
uniprot id: A0A3B4CTG0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:raf1a
gene id: 42514:raf1a
uniprot id: A0A3B4CVQ7
uniprot id: A0A3B4CZE9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

42514:ercc1
gene id: 42514:ercc1
uniprot id: A0A3B4BNS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

42514:si:dkey-37o8.1
gene id: 42514:si:dkey-37o8.1
uniprot id: A0A3B4BV77
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

42514:LOC108414085
gene id: 42514:LOC108414085
uniprot id: A0A3B4BNK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

42514:btf3l4
gene id: 42514:btf3l4
uniprot id: A0A3B4DSK5
names: Similarity
messages: Belongs to the NAC-beta family.

42514:hoxa3a
gene id: 42514:hoxa3a
uniprot id: A0A3B4BNE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

42514:LOC108428921
gene id: 42514:LOC108428921
uniprot id: A0A3B4EDN7
names: Subcellular Location Annotation
messages: Membrane

42514:ralba
gene id: 42514:ralba
uniprot id: A0A3B4CM17
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:sfrp5
gene id: 42514:sfrp5
uniprot id: A0A3B4DHV7
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ruvbl2
gene id: 42514:ruvbl2
uniprot id: A0A3B4DV14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

42514:LOC108441794
gene id: 42514:LOC108441794
uniprot id: A0A3B4CGM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:ephb2b
gene id: 42514:ephb2b
uniprot id: A0A3B4CSV4
names: Subcellular Location Annotation
messages: Membrane

42514:pou3f3b
gene id: 42514:pou3f3b
uniprot id: A0A3B4CUU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

42514:LOC108424983
gene id: 42514:LOC108424983
uniprot id: A0A3B4CWX1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:psmd5
gene id: 42514:psmd5
uniprot id: A0A3B4E6K8
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

42514:abl2
gene id: 42514:abl2
uniprot id: A0A3B4CKH4
uniprot id: A0A3B4E5S8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:dpp3
gene id: 42514:dpp3
uniprot id: A0A3B4C5J9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

42514:b4galt3
gene id: 42514:b4galt3
uniprot id: A0A3B4DZR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

42514:LOC108428580
gene id: 42514:LOC108428580
uniprot id: A0A3B4C192
uniprot id: A0A3B4DQF0
names: Similarity
messages: Belongs to the PAIP2 family.

42514:LOC108435922
gene id: 42514:LOC108435922
uniprot id: A0A3B4C4W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

42514:plcd4a
gene id: 42514:plcd4a
uniprot id: A0A3B4EEM4
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

42514:gsc
gene id: 42514:gsc
uniprot id: A0A3B4DKA9
names: Subcellular Location Annotation
messages: Nucleus

42514:adck2
gene id: 42514:adck2
uniprot id: A0A3B4D382
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

42514:gtpbp4
gene id: 42514:gtpbp4
uniprot id: A0A3B4E694
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

42514:LOC108444260
gene id: 42514:LOC108444260
uniprot id: A0A3B4DWW9
names: Subcellular Location Annotation
messages: Membrane

42514:pomt2
gene id: 42514:pomt2
uniprot id: A0A3B4CX17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

42514:b3galnt2
gene id: 42514:b3galnt2
uniprot id: A0A3B4BNI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:fam83hb
gene id: 42514:fam83hb
uniprot id: A0A3B4EJ42
names: Similarity
messages: Belongs to the FAM83 family.

42514:LOC108423643
gene id: 42514:LOC108423643
uniprot id: A0A3B4ENN2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

42514:LOC108423781
gene id: 42514:LOC108423781
uniprot id: A0A3B4E7X4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:p2ry8
gene id: 42514:p2ry8
uniprot id: A0A3B4CT19
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:camk2n1b
gene id: 42514:camk2n1b
uniprot id: A0A3B4CXX2
names: Similarity
messages: Belongs to the CAMK2N family.

42514:LOC108425948
gene id: 42514:LOC108425948
uniprot id: A0A3B4DFS3
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:psmd7
gene id: 42514:psmd7
uniprot id: A0A3B4DZ10
names: Similarity
messages: Belongs to the peptidase M67A family.

42514:rpia
gene id: 42514:rpia
uniprot id: A0A3B4E4B6
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

42514:cdkn1cb
gene id: 42514:cdkn1cb
uniprot id: A0A3B4BSJ4
names: Similarity
messages: Belongs to the CDI family.

42514:zgc:103625
gene id: 42514:zgc:103625
uniprot id: A0A3B4CDS5
names: Similarity
messages: Belongs to the UPF0585 family.

42514:LOC108424028
gene id: 42514:LOC108424028
uniprot id: A0A3B4DLZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:polr1b
gene id: 42514:polr1b
uniprot id: A0A3B4DU94
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

42514:brms1lb
gene id: 42514:brms1lb
uniprot id: A0A3B4BMY9
names: Subcellular Location Annotation
messages: Nucleus

42514:erbb2
gene id: 42514:erbb2
uniprot id: A0A3B4BWV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

42514:sumf2
gene id: 42514:sumf2
uniprot id: A0A3B4CJ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

42514:ing1
gene id: 42514:ing1
uniprot id: A0A3B4CUJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

42514:paip2b
gene id: 42514:paip2b
uniprot id: A0A3B4E4D2
names: Similarity
messages: Belongs to the PAIP2 family.

42514:apoea
gene id: 42514:apoea
uniprot id: A0A3B4BUS2
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

42514:hoxa2b
gene id: 42514:hoxa2b
uniprot id: A0A3B4DLV6
names: Subcellular Location Annotation
messages: Nucleus

42514:gale
gene id: 42514:gale
uniprot id: A0A3B4EF47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

42514:cacng1b
gene id: 42514:cacng1b
uniprot id: A0A3B4CJI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

42514:LOC108432196
gene id: 42514:LOC108432196
uniprot id: A0A3B4D6U7
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

42514:ddx61
gene id: 42514:ddx61
uniprot id: A0A3B4EFX0
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:smg8
gene id: 42514:smg8
uniprot id: A0A3B4DZC4
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

42514:LOC108443575
gene id: 42514:LOC108443575
uniprot id: A0A3B4DTE5
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

42514:phlda1
gene id: 42514:phlda1
uniprot id: A0A3B4CXN0
names: Subcellular Location Annotation
messages: Cytoplasm

42514:tubg1
gene id: 42514:tubg1
uniprot id: A0A3B4CH93
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

42514:suds3
gene id: 42514:suds3
uniprot id: A0A3B4DQI9
names: Subcellular Location Annotation
messages: Nucleus

42514:ngrn
gene id: 42514:ngrn
uniprot id: A0A3B4DHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

42514:csnk2a4
gene id: 42514:csnk2a4
uniprot id: A0A3B4BQY0
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:spsb4b
gene id: 42514:spsb4b
uniprot id: A0A3B4DAP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

42514:wscd1b
gene id: 42514:wscd1b
uniprot id: A0A3B4E003
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Golgi apparatus membrane
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

42514:rnft2
gene id: 42514:rnft2
uniprot id: A0A3B4D2F4
uniprot id: A0A3B4D2K0
names: Subcellular Location Annotation
messages: Membrane

42514:ache
gene id: 42514:ache
uniprot id: A0A3B4E5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

42514:mrps14
gene id: 42514:mrps14
uniprot id: A0A3B4CCQ4
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

42514:zgc:86764
gene id: 42514:zgc:86764
uniprot id: A0A3B4BYQ3
names: Similarity
messages: Belongs to the MAP65/ASE1 family.

42514:pdk4
gene id: 42514:pdk4
uniprot id: A0A3B4DEW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

42514:cenpn
gene id: 42514:cenpn
uniprot id: A0A3B4DMJ0
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

42514:spns3
gene id: 42514:spns3
uniprot id: A0A3B4C4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

42514:gch2
gene id: 42514:gch2
uniprot id: A0A3B4DMS8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

42514:aqp4
gene id: 42514:aqp4
uniprot id: A0A3B4DCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:shhb
gene id: 42514:shhb
uniprot id: A0A3B4CS27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

42514:mrpl53
gene id: 42514:mrpl53
uniprot id: A0A3B4C003
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

42514:crybb1
gene id: 42514:crybb1
uniprot id: A0A3B4BVR5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:ilvbl
gene id: 42514:ilvbl
uniprot id: A0A3B4DY13
names: Similarity
messages: Belongs to the TPP enzyme family.

42514:rap1ab
gene id: 42514:rap1ab
uniprot id: A0A3B4EK76
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:hbae5
gene id: 42514:hbae5
uniprot id: A0A3B4DQK6
names: Similarity
messages: Belongs to the globin family.

42514:gpia
gene id: 42514:gpia
uniprot id: A0A3B4DHH6
names: Similarity
messages: Belongs to the GPI family.

42514:osbpl3a
gene id: 42514:osbpl3a
uniprot id: A0A3B4BR20
names: Similarity
messages: Belongs to the OSBP family.

42514:ldlrad3
gene id: 42514:ldlrad3
uniprot id: A0A3B4EPU8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:foxi3a
gene id: 42514:foxi3a
uniprot id: A0A3B4DYM2
names: Subcellular Location Annotation
messages: Nucleus

42514:tm9sf4
gene id: 42514:tm9sf4
uniprot id: A0A3B4DJN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

42514:smfn
gene id: 42514:smfn
uniprot id: A0A3B4BR50
names: Similarity
messages: Belongs to the oligoribonuclease family.

42514:pnpla6
gene id: 42514:pnpla6
uniprot id: A0A3B4EEW1
uniprot id: A0A3B4EGD4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108412335
gene id: 42514:LOC108412335
uniprot id: A0A3B4C7I5
names: Subcellular Location Annotation
messages: Membrane

42514:actn3a
gene id: 42514:actn3a
uniprot id: A0A3B4DRT4
names: Similarity
messages: Belongs to the alpha-actinin family.

42514:tcea1
gene id: 42514:tcea1
uniprot id: A0A3B4CME2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

42514:sult2st3
gene id: 42514:sult2st3
uniprot id: A0A3B4DBF6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:upp1
gene id: 42514:upp1
uniprot id: A0A3B4C1E5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

42514:sst1.2
gene id: 42514:sst1.2
uniprot id: A0A3B4DX75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

42514:vkorc1
gene id: 42514:vkorc1
uniprot id: A0A3B4EAX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:fam118b
gene id: 42514:fam118b
uniprot id: A0A3B4DU77
names: Similarity
messages: Belongs to the FAM118 family.

42514:kcnab2a
gene id: 42514:kcnab2a
uniprot id: A0A3B4D874
uniprot id: A0A3B4DAT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

42514:LOC108439354
gene id: 42514:LOC108439354
uniprot id: A0A3B4D5G8
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:utp18
gene id: 42514:utp18
uniprot id: A0A3B4D5J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

42514:sub1b
gene id: 42514:sub1b
uniprot id: A0A3B4EF76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

42514:ccka
gene id: 42514:ccka
uniprot id: A0A3B4ECK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

42514:tomm22
gene id: 42514:tomm22
uniprot id: A0A3B4C0V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom22 family.
messages: Mitochondrion outer membrane

42514:meig1
gene id: 42514:meig1
uniprot id: A0A3B4BVA5
names: Function
names: Similarity
messages: Belongs to the MEIG1 family.
messages: Essential for spermiogenesis.

42514:LOC108412268
gene id: 42514:LOC108412268
uniprot id: A0A3B4E2F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

42514:slc47a1
gene id: 42514:slc47a1
uniprot id: A0A3B4CCZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

42514:crygn2
gene id: 42514:crygn2
uniprot id: A0A3B4EJS5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:LOC108429191
gene id: 42514:LOC108429191
uniprot id: A0A3B4C777
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF3 family.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.

42514:eaf1
gene id: 42514:eaf1
uniprot id: A0A3B4BX14
names: Similarity
messages: Belongs to the EAF family.

42514:LOC108431615
gene id: 42514:LOC108431615
uniprot id: A0A3B4DCC9
uniprot id: A0A3B4DDY3
names: Similarity
messages: Belongs to the filamin family.

42514:bola1
gene id: 42514:bola1
uniprot id: A0A3B4DDV6
names: Similarity
messages: Belongs to the BolA/IbaG family.

42514:LOC108431231
gene id: 42514:LOC108431231
uniprot id: A0A3B4DZC7
names: Subcellular Location Annotation
messages: Membrane

42514:slc7a3a
gene id: 42514:slc7a3a
uniprot id: A0A3B4C9G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

42514:tlr22
gene id: 42514:tlr22
uniprot id: A0A3B4CF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

42514:LOC108431254
gene id: 42514:LOC108431254
uniprot id: A0A3B4DVB0
names: Subcellular Location Annotation
messages: Membrane

42514:irx3b
gene id: 42514:irx3b
uniprot id: A0A3B4EPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

42514:cavin1a
gene id: 42514:cavin1a
uniprot id: A0A3B4CCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

42514:cnksr2b
gene id: 42514:cnksr2b
uniprot id: A0A3B4DZV6
names: Similarity
messages: Belongs to the CNKSR family.

42514:dusp16
gene id: 42514:dusp16
uniprot id: A0A3B4EMF6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

42514:LOC108425176
gene id: 42514:LOC108425176
uniprot id: A0A3B4CIM9
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108427489
gene id: 42514:LOC108427489
uniprot id: A0A3B4DQY6
names: Similarity
messages: Belongs to the ZC3H12 family.

42514:LOC108440247
gene id: 42514:LOC108440247
uniprot id: A0A3B4CFE4
names: Similarity
messages: Belongs to the globin family.

42514:creb5b
gene id: 42514:creb5b
uniprot id: A0A3B4BST2
uniprot id: A0A3B4DN67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.
messages: Binds to the cAMP response element and activates transcription.
messages: Nucleus

42514:spire2
gene id: 42514:spire2
uniprot id: A0A3B4CLE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

42514:phb
gene id: 42514:phb
uniprot id: A0A3B4C580
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

42514:tspan15
gene id: 42514:tspan15
uniprot id: A0A3B4EEF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:slc16a3
gene id: 42514:slc16a3
uniprot id: A0A3B4CB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

42514:sgcd
gene id: 42514:sgcd
uniprot id: A0A3B4CLS5
uniprot id: A0A3B4CLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

42514:mrps26
gene id: 42514:mrps26
uniprot id: A0A3B4E609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS26 family.
messages: Mitochondrion

42514:got1
gene id: 42514:got1
uniprot id: A0A3B4BL30
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

42514:smu1b
gene id: 42514:smu1b
uniprot id: A0A3B4CJP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

42514:plppr5a
gene id: 42514:plppr5a
uniprot id: A0A3B4DL31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:alkbh8
gene id: 42514:alkbh8
uniprot id: A0A3B4CUB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

42514:pax2a
gene id: 42514:pax2a
uniprot id: A0A3B4DJC3
uniprot id: A0A3B4DKC4
uniprot id: A0A3B4DKT5
names: Subcellular Location Annotation
messages: Nucleus

42514:cpne1
gene id: 42514:cpne1
uniprot id: A0A3B4BPC0
names: Similarity
messages: Belongs to the copine family.

42514:apoba
gene id: 42514:apoba
uniprot id: A0A3B4E6W9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:agtpbp1
gene id: 42514:agtpbp1
uniprot id: A0A3B4CHZ6
uniprot id: A0A3B4CM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

42514:zgc:113531
gene id: 42514:zgc:113531
uniprot id: A0A3B4DLU1
names: Subcellular Location Annotation
messages: Synapse

42514:si:dkeyp-75b4.8
gene id: 42514:si:dkeyp-75b4.8
uniprot id: A0A3B4DUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

42514:LOC108431223
gene id: 42514:LOC108431223
uniprot id: A0A3B4CHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

42514:cers4b
gene id: 42514:cers4b
uniprot id: A0A3B4EIY9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

42514:LOC108441946
gene id: 42514:LOC108441946
uniprot id: A0A3B4C2D5
names: Similarity
messages: Belongs to the S-100 family.

42514:lix1
gene id: 42514:lix1
uniprot id: A0A3B4D723
names: Similarity
messages: Belongs to the LIX1 family.

42514:elof1
gene id: 42514:elof1
uniprot id: A0A3B4BQA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

42514:olfml2a
gene id: 42514:olfml2a
uniprot id: A0A3B4C6C2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:lyve1b
gene id: 42514:lyve1b
uniprot id: A0A3B4E6B2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108427382
gene id: 42514:LOC108427382
uniprot id: A0A3B4E619
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

42514:dbr1
gene id: 42514:dbr1
uniprot id: A0A3B4EI50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

42514:b4galt5
gene id: 42514:b4galt5
uniprot id: A0A3B4D0L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

42514:slc7a14b
gene id: 42514:slc7a14b
uniprot id: A0A3B4DLS0
names: Subcellular Location Annotation
messages: Membrane

42514:clu
gene id: 42514:clu
uniprot id: A0A3B4BZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol

42514:chrna2a
gene id: 42514:chrna2a
uniprot id: A0A3B4BPM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:tufm
gene id: 42514:tufm
uniprot id: A0A3B4CNV5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

42514:mrpl49
gene id: 42514:mrpl49
uniprot id: A0A3B4ENZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

42514:LOC108440432
gene id: 42514:LOC108440432
uniprot id: A0A3B4DBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

42514:atg5
gene id: 42514:atg5
uniprot id: A0A3B4EPB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

42514:cln3
gene id: 42514:cln3
uniprot id: A0A3B4CWZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

42514:LOC108425691
gene id: 42514:LOC108425691
uniprot id: A0A3B4CDT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:abcc4
gene id: 42514:abcc4
uniprot id: A0A3B4DRQ9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane

42514:ca14
gene id: 42514:ca14
uniprot id: A0A3B4C3M3
uniprot id: A0A3B4DP98
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

42514:psmd12
gene id: 42514:psmd12
uniprot id: A0A3B4DDI3
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

42514:eef1a2
gene id: 42514:eef1a2
uniprot id: A0A3B4DJ54
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

42514:lypla2
gene id: 42514:lypla2
uniprot id: A0A3B4EKI1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

42514:sec22c
gene id: 42514:sec22c
uniprot id: A0A3B4CUB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

42514:hyou1
gene id: 42514:hyou1
uniprot id: A0A3B4DL52
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:LOC108424798
gene id: 42514:LOC108424798
uniprot id: A0A3B4EPJ1
names: Similarity
messages: Belongs to the MS4A family.

42514:heg1
gene id: 42514:heg1
uniprot id: A0A3B4DVF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dgat1a
gene id: 42514:dgat1a
uniprot id: A0A3B4CJQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

42514:lrp3
gene id: 42514:lrp3
uniprot id: A0A3B4DXA8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:rbbp4
gene id: 42514:rbbp4
uniprot id: A0A3B4DN59
names: Subcellular Location Annotation
messages: Nucleus

42514:trhrb
gene id: 42514:trhrb
uniprot id: A0A3B4EAS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

42514:ndufaf7
gene id: 42514:ndufaf7
uniprot id: A0A3B4DMJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

42514:tmx2b
gene id: 42514:tmx2b
uniprot id: A0A3B4DPP5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

42514:si:dkey-239i20.4
gene id: 42514:si:dkey-239i20.4
uniprot id: A0A3B4BRW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

42514:fam131bb
gene id: 42514:fam131bb
uniprot id: A0A3B4CTW7
uniprot id: A0A3B4E8Y6
names: Similarity
messages: Belongs to the FAM131 family.

42514:nav3
gene id: 42514:nav3
uniprot id: A0A3B4C4F7
names: Similarity
messages: Belongs to the Nav/unc-53 family.

42514:birc2
gene id: 42514:birc2
uniprot id: A0A3B4CBP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

42514:arap3
gene id: 42514:arap3
uniprot id: A0A3B4D6H0
names: Subcellular Location Annotation
messages: Cytoplasm

42514:fez2
gene id: 42514:fez2
uniprot id: A0A3B4DPQ3
uniprot id: A0A3B4DS88
names: Similarity
messages: Belongs to the zygin family.

42514:LOC108425280
gene id: 42514:LOC108425280
uniprot id: A0A3B4BMU4
names: Subcellular Location Annotation
messages: Nucleus

42514:hspa4l
gene id: 42514:hspa4l
uniprot id: A0A3B4CLG8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:LOC108425945
gene id: 42514:LOC108425945
uniprot id: A0A3B4DFS9
names: Similarity
messages: Belongs to the dynein intermediate chain family.

42514:LOC108414724
gene id: 42514:LOC108414724
uniprot id: A0A3B4CIA5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:pnoca
gene id: 42514:pnoca
uniprot id: A0A3B4EGW9
names: Similarity
messages: Belongs to the opioid neuropeptide precursor family.

42514:c2h20orf27
gene id: 42514:c2h20orf27
uniprot id: A0A3B4DBM4
names: Similarity
messages: Belongs to the ADISSP family.

42514:arpin
gene id: 42514:arpin
uniprot id: A0A3B4C6I3
names: Similarity
messages: Belongs to the Arpin family.

42514:arpc5b
gene id: 42514:arpc5b
uniprot id: A0A3B4CID9
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

42514:LOC108436793
gene id: 42514:LOC108436793
uniprot id: A0A3B4BTS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

42514:usp7
gene id: 42514:usp7
uniprot id: A0A3B4ED22
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:pcolcea
gene id: 42514:pcolcea
uniprot id: A0A3B4DHY0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:plxnb2b
gene id: 42514:plxnb2b
uniprot id: A0A3B4DBG5
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:zgc:153039
gene id: 42514:zgc:153039
uniprot id: A0A3B4CZN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:si:rp71-39b20.4
gene id: 42514:si:rp71-39b20.4
uniprot id: A0A3B4EM96
names: Subcellular Location Annotation
messages: Membrane

42514:flr
gene id: 42514:flr
uniprot id: A0A3B4EL09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

42514:riox1
gene id: 42514:riox1
uniprot id: A0A3B4DT88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

42514:LOC108424711
gene id: 42514:LOC108424711
uniprot id: A0A3B4DFM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

42514:zgc:114123
gene id: 42514:zgc:114123
uniprot id: A0A3B4EDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

42514:LOC108412848
gene id: 42514:LOC108412848
uniprot id: A0A3B4CPS8
names: Similarity
messages: Belongs to the cystatin family.

42514:akirin1
gene id: 42514:akirin1
uniprot id: A0A3B4CQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

42514:tmeff1b
gene id: 42514:tmeff1b
uniprot id: A0A3B4DTY0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:nr1d4b
gene id: 42514:nr1d4b
uniprot id: A0A3B4DFH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:guk1b
gene id: 42514:guk1b
uniprot id: A0A3B4E483
names: Similarity
messages: Belongs to the guanylate kinase family.

42514:psmd11a
gene id: 42514:psmd11a
uniprot id: A0A3B4DMX2
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

42514:LOC108443576
gene id: 42514:LOC108443576
uniprot id: A0A3B4ES67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

42514:sypa
gene id: 42514:sypa
uniprot id: A0A3B4C2U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

42514:ppifa
gene id: 42514:ppifa
uniprot id: A0A3B4DFY0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

42514:exosc9
gene id: 42514:exosc9
uniprot id: A0A3B4BRM8
names: Subcellular Location Annotation
messages: Cytoplasm

42514:osbpl5
gene id: 42514:osbpl5
uniprot id: A0A3B4BZL7
names: Similarity
messages: Belongs to the OSBP family.

42514:LOC108425037
gene id: 42514:LOC108425037
uniprot id: A0A3B4E6X0
names: Subcellular Location Annotation
messages: Membrane

42514:sfrp2l
gene id: 42514:sfrp2l
uniprot id: A0A3B4BND9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108441595
gene id: 42514:LOC108441595
uniprot id: A0A3B4DFT7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

42514:idua
gene id: 42514:idua
uniprot id: A0A3B4DT80
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

42514:vangl2
gene id: 42514:vangl2
uniprot id: A0A3B4CPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

42514:usp11
gene id: 42514:usp11
uniprot id: A0A3B4D3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

42514:plp2
gene id: 42514:plp2
uniprot id: A0A3B4CI40
names: Subcellular Location Annotation
messages: Membrane

42514:m17
gene id: 42514:m17
uniprot id: A0A3B4DKK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

42514:zfpm1
gene id: 42514:zfpm1
uniprot id: A0A3B4E3J7
names: Subcellular Location Annotation
messages: Nucleus

42514:txnrd2.2
gene id: 42514:txnrd2.2
uniprot id: A0A3B4DQ71
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

42514:dnase1l4.1
gene id: 42514:dnase1l4.1
uniprot id: A0A3B4EFZ5
names: Similarity
messages: Belongs to the DNase I family.

42514:ctsa
gene id: 42514:ctsa
uniprot id: A0A3B4DAG7
names: Similarity
messages: Belongs to the peptidase S10 family.

42514:stard8
gene id: 42514:stard8
uniprot id: A0A3B4BQM6
uniprot id: A0A3B4BTS4
names: Subcellular Location Annotation
messages: Cytoplasm

42514:ahr1b
gene id: 42514:ahr1b
uniprot id: A0A3B4E9H1
names: Subcellular Location Annotation
messages: Cytoplasm

42514:ern1
gene id: 42514:ern1
uniprot id: A0A3B4DGS3
names: Subcellular Location Annotation
messages: Membrane

42514:grpel2
gene id: 42514:grpel2
uniprot id: A0A3B4DXN3
names: Similarity
messages: Belongs to the GrpE family.

42514:eef2k
gene id: 42514:eef2k
uniprot id: A0A3B4CA84
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

42514:nelfcd
gene id: 42514:nelfcd
uniprot id: A0A3B4C5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

42514:hnf1a
gene id: 42514:hnf1a
uniprot id: A0A3B4ELV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

42514:bbs2
gene id: 42514:bbs2
uniprot id: A0A3B4CHP1
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

42514:myo1b
gene id: 42514:myo1b
uniprot id: A0A3B4CMM8
uniprot id: A0A3B4E642
uniprot id: A0A3B4E6D9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:fign
gene id: 42514:fign
uniprot id: A0A3B4EDB6
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:taf10
gene id: 42514:taf10
uniprot id: A0A3B4EDP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus
messages: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.

42514:pthlha
gene id: 42514:pthlha
uniprot id: A0A3B4BSR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

42514:zmp:0000000936
gene id: 42514:zmp:0000000936
uniprot id: A0A3B4EDV7
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

42514:slc4a2a
gene id: 42514:slc4a2a
uniprot id: A0A3B4CT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

42514:celf1
gene id: 42514:celf1
uniprot id: A0A3B4C710
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

42514:hcfc2
gene id: 42514:hcfc2
uniprot id: A0A3B4C083
names: Subcellular Location Annotation
messages: Nucleus

42514:pmela
gene id: 42514:pmela
uniprot id: A0A3B4BQ48
names: Similarity
messages: Belongs to the PMEL/NMB family.

42514:LOC108414103
gene id: 42514:LOC108414103
uniprot id: A0A3B4DTP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

42514:tnnt1
gene id: 42514:tnnt1
uniprot id: A0A3B4CJ40
uniprot id: A0A3B4E2F7
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

42514:aida
gene id: 42514:aida
uniprot id: A0A3B4BWN9
names: Similarity
messages: Belongs to the AIDA family.

42514:lef1
gene id: 42514:lef1
uniprot id: A0A3B4CPS9
uniprot id: A0A3B4E8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

42514:srp54
gene id: 42514:srp54
uniprot id: A0A3B4DKQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Nucleus speckle
messages: The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.
messages: The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.

42514:camk2n2
gene id: 42514:camk2n2
uniprot id: A0A3B4C113
names: Similarity
messages: Belongs to the CAMK2N family.

42514:polr2h
gene id: 42514:polr2h
uniprot id: A0A3B4C0J2
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

42514:ptpn21
gene id: 42514:ptpn21
uniprot id: A0A3B4BPS6
uniprot id: A0A3B4BSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

42514:LOC108421350
gene id: 42514:LOC108421350
uniprot id: A0A3B4E0V3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

42514:pax1a
gene id: 42514:pax1a
uniprot id: A0A3B4CHY1
names: Subcellular Location Annotation
messages: Nucleus

42514:ptges3a
gene id: 42514:ptges3a
uniprot id: A0A3B4EG63
names: Similarity
messages: Belongs to the p23/wos2 family.

42514:ecsit
gene id: 42514:ecsit
uniprot id: A0A3B4DXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ECSIT family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus

42514:emp3b
gene id: 42514:emp3b
uniprot id: A0A3B4DTD0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:marcksa
gene id: 42514:marcksa
uniprot id: A0A3B4E4P9
names: Similarity
messages: Belongs to the MARCKS family.

42514:LOC108430889
gene id: 42514:LOC108430889
uniprot id: A0A3B4C5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

42514:LOC108443080
gene id: 42514:LOC108443080
uniprot id: A0A3B4C7Z3
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:hspb3
gene id: 42514:hspb3
uniprot id: A0A3B4CU67
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

42514:osbpl1a
gene id: 42514:osbpl1a
uniprot id: A0A3B4EDR3
uniprot id: A0A3B4EDS4
names: Similarity
messages: Belongs to the OSBP family.

42514:ddt
gene id: 42514:ddt
uniprot id: A0A3B4E3H4
names: Similarity
messages: Belongs to the MIF family.

42514:LOC108411194
gene id: 42514:LOC108411194
uniprot id: A0A3B4DYC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

42514:rictora
gene id: 42514:rictora
uniprot id: A0A3B4CDH7
names: Similarity
messages: Belongs to the RICTOR family.

42514:lmod2a
gene id: 42514:lmod2a
uniprot id: A0A3B4CGX6
names: Subcellular Location Annotation
messages: cytoskeleton

42514:fabp4a
gene id: 42514:fabp4a
uniprot id: A0A3B4BWN8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:LOC108436223
gene id: 42514:LOC108436223
uniprot id: A0A3B4E1K6
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:kmt2a
gene id: 42514:kmt2a
uniprot id: A0A3B4EEY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
messages: Nucleus

42514:oafb
gene id: 42514:oafb
uniprot id: A0A3B4CFW0
names: Similarity
messages: Belongs to the OAF family.

42514:gpn3
gene id: 42514:gpn3
uniprot id: A0A3B4CEN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

42514:ninj1
gene id: 42514:ninj1
uniprot id: A0A3B4DNH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

42514:fam168a
gene id: 42514:fam168a
uniprot id: A0A3B4CRD9
names: Similarity
messages: Belongs to the FAM168 family.

42514:igf2b
gene id: 42514:igf2b
uniprot id: A0A3B4DM38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

42514:ctsla
gene id: 42514:ctsla
uniprot id: A0A3B4DYV3
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:LOC108414843
gene id: 42514:LOC108414843
uniprot id: A0A3B4DUJ2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

42514:kcnh5a
gene id: 42514:kcnh5a
uniprot id: A0A3B4D8P3
names: Subcellular Location Annotation
messages: Membrane

42514:ppp1r14aa
gene id: 42514:ppp1r14aa
uniprot id: A0A3B4D3U6
names: Similarity
messages: Belongs to the PP1 inhibitor family.

42514:chst2b
gene id: 42514:chst2b
uniprot id: A0A3B4DGK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

42514:nr1i2
gene id: 42514:nr1i2
uniprot id: A0A3B4CTB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:aplnr2
gene id: 42514:aplnr2
uniprot id: A0A3B4D4W9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:zgc:162331
gene id: 42514:zgc:162331
uniprot id: A0A3B4CW92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:sap130b
gene id: 42514:sap130b
uniprot id: A0A3B4BYE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

42514:otog
gene id: 42514:otog
uniprot id: A0A3B4EHW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108439477
gene id: 42514:LOC108439477
uniprot id: A0A3B4CTL6
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

42514:neurl2
gene id: 42514:neurl2
uniprot id: A0A3B4BZN5
names: Subcellular Location Annotation
messages: Cytoplasm

42514:p3h1
gene id: 42514:p3h1
uniprot id: A0A3B4BY09
names: Similarity
messages: Belongs to the leprecan family.

42514:fgf2
gene id: 42514:fgf2
uniprot id: A0A3B4CZH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

42514:alas2
gene id: 42514:alas2
uniprot id: A0A3B4D8V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

42514:si:ch211-234h8.7
gene id: 42514:si:ch211-234h8.7
uniprot id: A0A3B4CAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

42514:bet1l
gene id: 42514:bet1l
uniprot id: A0A3B4DHP0
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108439293
gene id: 42514:LOC108439293
uniprot id: A0A3B4DFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

42514:lsm12b
gene id: 42514:lsm12b
uniprot id: A0A3B4DA16
names: Similarity
messages: Belongs to the LSM12 family.

42514:tyrp1b
gene id: 42514:tyrp1b
uniprot id: A0A3B4BND2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

42514:crata
gene id: 42514:crata
uniprot id: A0A3B4D191
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

42514:chpt1
gene id: 42514:chpt1
uniprot id: A0A3B4E343
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

42514:mmachc
gene id: 42514:mmachc
uniprot id: A0A3B4BP35
names: Similarity
messages: Belongs to the MMACHC family.

42514:fxyd1
gene id: 42514:fxyd1
uniprot id: A0A3B4EK80
names: Similarity
messages: Belongs to the FXYD family.

42514:triap1
gene id: 42514:triap1
uniprot id: A0A3B4E7W4
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

42514:oxtrl
gene id: 42514:oxtrl
uniprot id: A0A3B4BYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:hhat
gene id: 42514:hhat
uniprot id: A0A3B4C493
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108443884
gene id: 42514:LOC108443884
uniprot id: A0A3B4BPH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:gda
gene id: 42514:gda
uniprot id: A0A3B4D1D8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

42514:ppp1cc
gene id: 42514:ppp1cc
uniprot id: A0A3B4EKK2
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

42514:aqp7
gene id: 42514:aqp7
uniprot id: A0A3B4D5D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:palm2akap2
gene id: 42514:palm2akap2
uniprot id: A0A3B4CG73
uniprot id: A0A3B4CKF1
names: Similarity
messages: Belongs to the paralemmin family.

42514:LOC108434831
gene id: 42514:LOC108434831
uniprot id: A0A3B4DST6
names: Similarity
messages: Belongs to the cornifelin family.

42514:mrpl14
gene id: 42514:mrpl14
uniprot id: A0A3B4E5A1
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

42514:adcyap1a
gene id: 42514:adcyap1a
uniprot id: A0A3B4EBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

42514:ilk
gene id: 42514:ilk
uniprot id: A0A3B4CKZ1
names: Subcellular Location Annotation
messages: lamellipodium
messages: sarcomere

42514:rps12
gene id: 42514:rps12
uniprot id: A0A3B4D803
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

42514:gjd1a
gene id: 42514:gjd1a
uniprot id: A0A3B4C684
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:snx21
gene id: 42514:snx21
uniprot id: A0A3B4BR01
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

42514:slco3a1
gene id: 42514:slco3a1
uniprot id: A0A3B4CHG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

42514:sumo2a
gene id: 42514:sumo2a
uniprot id: A0A3B4DXR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

42514:rsl24d1
gene id: 42514:rsl24d1
uniprot id: A0A3B4CP34
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

42514:si:dkey-27c15.3
gene id: 42514:si:dkey-27c15.3
uniprot id: A0A3B4D893
names: Subcellular Location Annotation
messages: Nucleus

42514:rngtt
gene id: 42514:rngtt
uniprot id: A0A3B4CAR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

42514:tmed1a
gene id: 42514:tmed1a
uniprot id: A0A3B4E8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

42514:runx3
gene id: 42514:runx3
uniprot id: A0A3B4CFK1
names: Subcellular Location Annotation
messages: Nucleus

42514:tiprl
gene id: 42514:tiprl
uniprot id: A0A3B4E659
names: Similarity
messages: Belongs to the TIP41 family.

42514:prox1a
gene id: 42514:prox1a
uniprot id: A0A3B4D765
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108430143
gene id: 42514:LOC108430143
uniprot id: A0A3B4C902
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:adamts8a
gene id: 42514:adamts8a
uniprot id: A0A3B4C272
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:LOC108444230
gene id: 42514:LOC108444230
uniprot id: A0A3B4CF89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:intu
gene id: 42514:intu
uniprot id: A0A3B4CTD0
uniprot id: A0A3B4CTI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

42514:si:ch211-221n20.8
gene id: 42514:si:ch211-221n20.8
uniprot id: A0A3B4DKB6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:zdhhc3b
gene id: 42514:zdhhc3b
uniprot id: A0A3B4E4B8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:nr5a2
gene id: 42514:nr5a2
uniprot id: A0A3B4CCJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

42514:zgc:171572
gene id: 42514:zgc:171572
uniprot id: A0A3B4CNZ1
uniprot id: A0A3B4E6X2
names: Similarity
messages: Belongs to the BicD family.

42514:LOC108443424
gene id: 42514:LOC108443424
uniprot id: A0A3B4CZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

42514:cnfn
gene id: 42514:cnfn
uniprot id: A0A3B4CSR0
names: Similarity
messages: Belongs to the cornifelin family.

42514:LOC108413844
gene id: 42514:LOC108413844
uniprot id: A0A3B4EJM5
names: Similarity
messages: Belongs to the serpin family.

42514:phb2a
gene id: 42514:phb2a
uniprot id: A0A3B4DPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

42514:tmem200ca
gene id: 42514:tmem200ca
uniprot id: A0A3B4D409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

42514:pnp5a
gene id: 42514:pnp5a
uniprot id: A0A3B4DPN9
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

42514:yipf4
gene id: 42514:yipf4
uniprot id: A0A3B4BZW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:xylb
gene id: 42514:xylb
uniprot id: A0A3B4EI44
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

42514:ntrk3b
gene id: 42514:ntrk3b
uniprot id: A0A3B4C7B3
uniprot id: A0A3B4C970
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:LOC108424565
gene id: 42514:LOC108424565
uniprot id: A0A3B4BN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

42514:mpp7a
gene id: 42514:mpp7a
uniprot id: A0A3B4DSJ8
names: Similarity
messages: Belongs to the MAGUK family.

42514:cdo1
gene id: 42514:cdo1
uniprot id: A0A3B4C8S5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

42514:mark1
gene id: 42514:mark1
uniprot id: A0A3B4C322
uniprot id: A0A3B4DSW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

42514:mri1
gene id: 42514:mri1
uniprot id: A0A3B4C6F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

42514:atat1
gene id: 42514:atat1
uniprot id: A0A3B4D964
uniprot id: A0A3B4D978
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. May be involved in neuron development.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

42514:psmd2
gene id: 42514:psmd2
uniprot id: A0A3B4DP07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

42514:tfap2d
gene id: 42514:tfap2d
uniprot id: A0A3B4C6K1
names: Similarity
messages: Belongs to the AP-2 family.

42514:st6gal1
gene id: 42514:st6gal1
uniprot id: A0A3B4E0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:mgmt
gene id: 42514:mgmt
uniprot id: A0A3B4D7C8
names: Function
names: Similarity
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

42514:rpl22l1
gene id: 42514:rpl22l1
uniprot id: A0A3B4BQT6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

42514:si:ch211-212k18.7
gene id: 42514:si:ch211-212k18.7
uniprot id: A0A3B4CQ02
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

42514:vipr1a
gene id: 42514:vipr1a
uniprot id: A0A3B4ENX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

42514:urm1
gene id: 42514:urm1
uniprot id: A0A3B4CHG2
uniprot id: A0A3B4CKT8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Cytoplasm

42514:capn9
gene id: 42514:capn9
uniprot id: A0A3B4E5I7
names: Similarity
messages: Belongs to the peptidase C2 family.

42514:cnih4
gene id: 42514:cnih4
uniprot id: A0A3B4C4E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

42514:abcb8
gene id: 42514:abcb8
uniprot id: A0A3B4E0V6
names: Subcellular Location Annotation
messages: Membrane

42514:pdgfrb
gene id: 42514:pdgfrb
uniprot id: A0A3B4DS17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:lztfl1
gene id: 42514:lztfl1
uniprot id: A0A3B4E1Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

42514:hdac8
gene id: 42514:hdac8
uniprot id: A0A3B4DQH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility. In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones.
messages: Nucleus

42514:chsy1
gene id: 42514:chsy1
uniprot id: A0A3B4DWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

42514:ap3s2
gene id: 42514:ap3s2
uniprot id: A0A3B4CHG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

42514:dis3l2
gene id: 42514:dis3l2
uniprot id: A0A3B4DFG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

42514:spock3
gene id: 42514:spock3
uniprot id: A0A3B4C372
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:hnf4g
gene id: 42514:hnf4g
uniprot id: A0A3B4CX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

42514:LOC108441013
gene id: 42514:LOC108441013
uniprot id: A0A3B4DGR1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:nudt12
gene id: 42514:nudt12
uniprot id: A0A3B4BWR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

42514:si:ch211-251b21.1
gene id: 42514:si:ch211-251b21.1
uniprot id: A0A3B4D8T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:il2rb
gene id: 42514:il2rb
uniprot id: A0A3B4CP31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane

42514:igfbp2a
gene id: 42514:igfbp2a
uniprot id: A0A3B4BT42
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:mul1a
gene id: 42514:mul1a
uniprot id: A0A3B4CW21
names: Subcellular Location Annotation
messages: Membrane

42514:pgm3
gene id: 42514:pgm3
uniprot id: A0A3B4D1X9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

42514:extl3
gene id: 42514:extl3
uniprot id: A0A3B4C379
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

42514:zhx3
gene id: 42514:zhx3
uniprot id: A0A3B4D2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

42514:LOC108436916
gene id: 42514:LOC108436916
uniprot id: A0A3B4E2C2
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

42514:dmrt2b
gene id: 42514:dmrt2b
uniprot id: A0A3B4DQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

42514:dnase2b
gene id: 42514:dnase2b
uniprot id: A0A3B4CIB4
names: Similarity
messages: Belongs to the DNase II family.

42514:emc3
gene id: 42514:emc3
uniprot id: A0A3B4CGG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

42514:LOC108430263
gene id: 42514:LOC108430263
uniprot id: A0A3B4BV37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

42514:gsdmea
gene id: 42514:gsdmea
uniprot id: A0A3B4BR08
names: Similarity
messages: Belongs to the gasdermin family.

42514:LOC108435399
gene id: 42514:LOC108435399
uniprot id: A0A3B4BUX3
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

42514:strip2
gene id: 42514:strip2
uniprot id: A0A3B4EMF8
names: Similarity
messages: Belongs to the STRIP family.

42514:atp6v1f
gene id: 42514:atp6v1f
uniprot id: A0A3B4BVP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

42514:stat6
gene id: 42514:stat6
uniprot id: A0A3B4EJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

42514:xrcc4
gene id: 42514:xrcc4
uniprot id: A0A3B4DM85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

42514:cluap1
gene id: 42514:cluap1
uniprot id: A0A3B4C896
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

42514:gins3
gene id: 42514:gins3
uniprot id: A0A3B4C0T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

42514:per1a
gene id: 42514:per1a
uniprot id: A0A3B4BPT2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:LOC108442150
gene id: 42514:LOC108442150
uniprot id: A0A3B4D923
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

42514:zgc:110319
gene id: 42514:zgc:110319
uniprot id: A0A3B4EIG2
names: Similarity
messages: Belongs to the NifU family.

42514:zgc:153409
gene id: 42514:zgc:153409
uniprot id: A0A3B4EQP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:opa1
gene id: 42514:opa1
uniprot id: A0A3B4DSD1
uniprot id: A0A3B4DTM0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

42514:slc30a5
gene id: 42514:slc30a5
uniprot id: A0A3B4DBX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Membrane
messages: trans-Golgi network membrane

42514:vps26bl
gene id: 42514:vps26bl
uniprot id: A0A3B4CRM8
names: Similarity
messages: Belongs to the VPS26 family.

42514:cpsf6
gene id: 42514:cpsf6
uniprot id: A0A3B4EFN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

42514:tafa5l
gene id: 42514:tafa5l
uniprot id: A0A3B4CH40
names: Similarity
messages: Belongs to the TAFA family.

42514:spon1a
gene id: 42514:spon1a
uniprot id: A0A3B4DDY1
names: Subcellular Location Annotation
messages: extracellular matrix

42514:immp2l
gene id: 42514:immp2l
uniprot id: A0A3B4CIU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

42514:LOC108411664
gene id: 42514:LOC108411664
uniprot id: A0A3B4CSF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

42514:asz1
gene id: 42514:asz1
uniprot id: A0A3B4C7X2
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.

42514:sntb1
gene id: 42514:sntb1
uniprot id: A0A3B4DPM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

42514:serping1
gene id: 42514:serping1
uniprot id: A0A3B4CN53
names: Similarity
messages: Belongs to the serpin family.

42514:chrna11
gene id: 42514:chrna11
uniprot id: A0A3B4E480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:fxr1
gene id: 42514:fxr1
uniprot id: A0A3B4CUS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule

42514:LOC108436201
gene id: 42514:LOC108436201
uniprot id: A0A3B4E479
names: Subcellular Location Annotation
messages: Nucleus

42514:atp1b4
gene id: 42514:atp1b4
uniprot id: A0A3B4CWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

42514:stra6
gene id: 42514:stra6
uniprot id: A0A3B4DIX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:arl3l1
gene id: 42514:arl3l1
uniprot id: A0A3B4CAF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

42514:dars2
gene id: 42514:dars2
uniprot id: A0A3B4DNY8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

42514:dusp27
gene id: 42514:dusp27
uniprot id: A0A3B4C335
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

42514:LOC108443606
gene id: 42514:LOC108443606
uniprot id: A0A3B4C3Z2
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:gnrhr4
gene id: 42514:gnrhr4
uniprot id: A0A3B4CJV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:htra3b
gene id: 42514:htra3b
uniprot id: A0A3B4C4M9
names: Similarity
messages: Belongs to the peptidase S1C family.

42514:setdb2
gene id: 42514:setdb2
uniprot id: A0A3B4C2B4
names: Subcellular Location Annotation
messages: Chromosome

42514:LOC108410946
gene id: 42514:LOC108410946
uniprot id: A0A3B4D4F5
uniprot id: A0A3B4D7V2
names: Similarity
messages: Belongs to the MHC class I family.

42514:si:ch211-286o17.1
gene id: 42514:si:ch211-286o17.1
uniprot id: A0A3B4DQV3
names: Subcellular Location Annotation
messages: Membrane

42514:sncgb
gene id: 42514:sncgb
uniprot id: A0A3B4BY94
uniprot id: A0A3B4DKZ2
names: Similarity
messages: Belongs to the synuclein family.

42514:srd5a1
gene id: 42514:srd5a1
uniprot id: A0A3B4D8M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Microsome membrane

42514:bnip3
gene id: 42514:bnip3
uniprot id: A0A3B4C829
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

42514:ndst2a
gene id: 42514:ndst2a
uniprot id: A0A3B4DJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

42514:inpp4aa
gene id: 42514:inpp4aa
uniprot id: A0A3B4DMX3
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

42514:LOC108411508
gene id: 42514:LOC108411508
uniprot id: A0A3B4EF05
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

42514:opa3
gene id: 42514:opa3
uniprot id: A0A3B4EQC1
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

42514:noc2l
gene id: 42514:noc2l
uniprot id: A0A3B4E9Y2
names: Similarity
messages: Belongs to the NOC2 family.

42514:trim9
gene id: 42514:trim9
uniprot id: A0A3B4CB70
uniprot id: A0A3B4DWK4
names: Subcellular Location Annotation
messages: cytoskeleton

42514:usp22
gene id: 42514:usp22
uniprot id: A0A3B4CSM0
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:suv39h1a
gene id: 42514:suv39h1a
uniprot id: A0A3B4CHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

42514:LOC108415428
gene id: 42514:LOC108415428
uniprot id: A0A3B4CLW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:wdr48b
gene id: 42514:wdr48b
uniprot id: A0A3B4EIC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Late endosome

42514:dcps
gene id: 42514:dcps
uniprot id: A0A3B4BQR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Cytoplasm
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

42514:lsm14aa
gene id: 42514:lsm14aa
uniprot id: A0A3B4BNZ1
uniprot id: A0A3B4BPH1
names: Similarity
messages: Belongs to the LSM14 family.

42514:plpp4
gene id: 42514:plpp4
uniprot id: A0A3B4D0W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:LOC108442487
gene id: 42514:LOC108442487
uniprot id: A0A3B4C681
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

42514:fbxo32
gene id: 42514:fbxo32
uniprot id: A0A3B4D3Z5
names: Subcellular Location Annotation
messages: Nucleus

42514:ipo13
gene id: 42514:ipo13
uniprot id: A0A3B4DJV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

42514:slc25a48
gene id: 42514:slc25a48
uniprot id: A0A3B4D565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:rgs7bpa
gene id: 42514:rgs7bpa
uniprot id: A0A3B4CX75
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

42514:pde4ca
gene id: 42514:pde4ca
uniprot id: A0A3B4DH43
uniprot id: A0A3B4DH87
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:LOC108432121
gene id: 42514:LOC108432121
uniprot id: A0A3B4DIA0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:sst2
gene id: 42514:sst2
uniprot id: A0A3B4DB04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

42514:vegfaa
gene id: 42514:vegfaa
uniprot id: A0A3B4E6K7
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

42514:sema5a
gene id: 42514:sema5a
uniprot id: A0A3B4CZC3
uniprot id: A0A3B4EFA8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:atg4a
gene id: 42514:atg4a
uniprot id: A0A3B4D8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

42514:tasora
gene id: 42514:tasora
uniprot id: A0A3B4EM89
uniprot id: A0A3B4EP80
names: Similarity
messages: Belongs to the TASOR family.

42514:ubiad1
gene id: 42514:ubiad1
uniprot id: A0A3B4E7D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

42514:tnfa
gene id: 42514:tnfa
uniprot id: A0A3B4EMD7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:abca5
gene id: 42514:abca5
uniprot id: A0A3B4BQT1
names: Subcellular Location Annotation
messages: Membrane

42514:unk
gene id: 42514:unk
uniprot id: A0A3B4C1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

42514:cpeb3
gene id: 42514:cpeb3
uniprot id: A0A3B4C4J9
uniprot id: A0A3B4DTF4
names: Similarity
messages: Belongs to the RRM CPEB family.

42514:dkk1a
gene id: 42514:dkk1a
uniprot id: A0A3B4ERP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

42514:LOC108427189
gene id: 42514:LOC108427189
uniprot id: A0A3B4D2R5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:psenen
gene id: 42514:psenen
uniprot id: A0A3B4C8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

42514:dand5
gene id: 42514:dand5
uniprot id: A0A3B4EAW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

42514:LOC108430321
gene id: 42514:LOC108430321
uniprot id: A0A3B4BSI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:dhx58
gene id: 42514:dhx58
uniprot id: A0A3B4EMP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

42514:prkrip1
gene id: 42514:prkrip1
uniprot id: A0A3B4CEH6
names: Similarity
messages: Belongs to the PRKRIP1 family.

42514:tpp1
gene id: 42514:tpp1
uniprot id: A0A3B4CM34
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:c15h6orf120
gene id: 42514:c15h6orf120
uniprot id: A0A3B4C117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

42514:flot2b
gene id: 42514:flot2b
uniprot id: A0A3B4CN87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

42514:impdh2
gene id: 42514:impdh2
uniprot id: A0A3B4CT00
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

42514:si:ch211-200p22.4
gene id: 42514:si:ch211-200p22.4
uniprot id: A0A3B4C967
uniprot id: A0A3B4DU82
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

42514:sox21b
gene id: 42514:sox21b
uniprot id: A0A3B4EH42
names: Subcellular Location Annotation
messages: Nucleus

42514:si:dkey-246g23.4
gene id: 42514:si:dkey-246g23.4
uniprot id: A0A3B4CTV9
names: Subcellular Location Annotation
messages: Membrane

42514:slc66a2
gene id: 42514:slc66a2
uniprot id: A0A3B4D1Z5
uniprot id: A0A3B4D238
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108442070
gene id: 42514:LOC108442070
uniprot id: A0A3B4DIR6
names: Similarity
messages: Belongs to the acylphosphatase family.

42514:trip13
gene id: 42514:trip13
uniprot id: A0A3B4BQP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.

42514:zgc:122979
gene id: 42514:zgc:122979
uniprot id: A0A3B4E386
names: Similarity
messages: Belongs to the globin family.

42514:LOC108440755
gene id: 42514:LOC108440755
uniprot id: A0A3B4DYB4
names: Subcellular Location Annotation
messages: Nucleus

42514:pdcl3
gene id: 42514:pdcl3
uniprot id: A0A3B4CNQ6
names: Similarity
messages: Belongs to the phosducin family.

42514:galnt13
gene id: 42514:galnt13
uniprot id: A0A3B4CKE3
uniprot id: A0A3B4CPI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:hdac9b
gene id: 42514:hdac9b
uniprot id: A0A3B4CFX8
uniprot id: A0A3B4CIN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus

42514:slc5a6b
gene id: 42514:slc5a6b
uniprot id: A0A3B4BLA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:LOC108429244
gene id: 42514:LOC108429244
uniprot id: A0A3B4DP45
uniprot id: A0A3B4DP61
uniprot id: A0A3B4DSQ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108427094
gene id: 42514:LOC108427094
uniprot id: A0A3B4DBE5
names: Similarity
messages: Belongs to the ANKRD34 family.

42514:pwp2h
gene id: 42514:pwp2h
uniprot id: A0A3B4CMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

42514:adora2ab
gene id: 42514:adora2ab
uniprot id: A0A3B4DIH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

42514:arrdc3a
gene id: 42514:arrdc3a
uniprot id: A0A3B4DX66
names: Similarity
messages: Belongs to the arrestin family.

42514:slc30a9
gene id: 42514:slc30a9
uniprot id: A0A3B4EB87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

42514:bcat2
gene id: 42514:bcat2
uniprot id: A0A3B4DG97
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

42514:ankrd13b
gene id: 42514:ankrd13b
uniprot id: A0A3B4DN23
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

42514:ism2a
gene id: 42514:ism2a
uniprot id: A0A3B4CNF4
names: Similarity
messages: Belongs to the isthmin family.

42514:LOC108430644
gene id: 42514:LOC108430644
uniprot id: A0A3B4CTZ7
names: Similarity
messages: Belongs to the phospholipase D family.

42514:bag6
gene id: 42514:bag6
uniprot id: A0A3B4DLP3
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol
messages: extracellular exosome

42514:LOC108428931
gene id: 42514:LOC108428931
uniprot id: A0A3B4CVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

42514:kdrl
gene id: 42514:kdrl
uniprot id: A0A3B4E6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:eif3ja
gene id: 42514:eif3ja
uniprot id: A0A3B4E527
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

42514:cnrip1a
gene id: 42514:cnrip1a
uniprot id: A0A3B4E4X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

42514:chuk
gene id: 42514:chuk
uniprot id: A0A3B4CC00
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:prr15lb
gene id: 42514:prr15lb
uniprot id: A0A3B4DH72
names: Similarity
messages: Belongs to the PRR15 family.

42514:erbb3b
gene id: 42514:erbb3b
uniprot id: A0A3B4CSL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

42514:LOC108443953
gene id: 42514:LOC108443953
uniprot id: A0A3B4D8C2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:gareml
gene id: 42514:gareml
uniprot id: A0A3B4C5L2
names: Similarity
messages: Belongs to the GAREM family.

42514:LOC108424624
gene id: 42514:LOC108424624
uniprot id: A0A3B4DIB7
names: Subcellular Location Annotation
messages: Nucleus

42514:neurod4
gene id: 42514:neurod4
uniprot id: A0A3B4CZ18
names: Subcellular Location Annotation
messages: Nucleus

42514:wasf2
gene id: 42514:wasf2
uniprot id: A0A3B4EJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

42514:foxd5
gene id: 42514:foxd5
uniprot id: A0A3B4CBU6
names: Subcellular Location Annotation
messages: Nucleus

42514:sf3a3
gene id: 42514:sf3a3
uniprot id: A0A3B4BZ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3A3 family.
messages: Nucleus

42514:ubald1b
gene id: 42514:ubald1b
uniprot id: A0A3B4DR36
names: Similarity
messages: Belongs to the UBALD family.

42514:atg13
gene id: 42514:atg13
uniprot id: A0A3B4EKK8
uniprot id: A0A3B4EKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

42514:amer3
gene id: 42514:amer3
uniprot id: A0A3B4CRJ1
names: Similarity
messages: Belongs to the Amer family.

42514:rpl22
gene id: 42514:rpl22
uniprot id: A0A3B4D867
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

42514:gadd45aa
gene id: 42514:gadd45aa
uniprot id: A0A3B4EKN5
names: Similarity
messages: Belongs to the GADD45 family.

42514:mms22l
gene id: 42514:mms22l
uniprot id: A0A3B4BNC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

42514:gpr39
gene id: 42514:gpr39
uniprot id: A0A3B4D3S0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:adma
gene id: 42514:adma
uniprot id: A0A3B4DYW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

42514:imp4
gene id: 42514:imp4
uniprot id: A0A3B4C0V2
names: Subcellular Location Annotation
messages: nucleolus

42514:tagln3a
gene id: 42514:tagln3a
uniprot id: A0A3B4EPM9
names: Similarity
messages: Belongs to the calponin family.

42514:rab11fip4a
gene id: 42514:rab11fip4a
uniprot id: A0A3B4CDC1
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

42514:dlgap1b
gene id: 42514:dlgap1b
uniprot id: A0A3B4D9U5
uniprot id: A0A3B4DDI6
names: Similarity
messages: Belongs to the SAPAP family.

42514:lmna
gene id: 42514:lmna
uniprot id: A0A3B4C3G3
names: Similarity
messages: Belongs to the intermediate filament family.

42514:slc25a37
gene id: 42514:slc25a37
uniprot id: A0A3B4CSF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:sec23b
gene id: 42514:sec23b
uniprot id: A0A3B4BZL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

42514:isl2a
gene id: 42514:isl2a
uniprot id: A0A3B4DZU2
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108439741
gene id: 42514:LOC108439741
uniprot id: A0A3B4C198
uniprot id: A0A3B4DUC5
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

42514:meltf
gene id: 42514:meltf
uniprot id: A0A3B4D748
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.

42514:hspb6
gene id: 42514:hspb6
uniprot id: A0A3B4DXG7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

42514:pitpnm3
gene id: 42514:pitpnm3
uniprot id: A0A3B4BTE6
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

42514:tle2b
gene id: 42514:tle2b
uniprot id: A0A3B4CPW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

42514:ube2d1b
gene id: 42514:ube2d1b
uniprot id: A0A3B4E899
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:zgc:162171
gene id: 42514:zgc:162171
uniprot id: A0A3B4CBT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

42514:efhc1
gene id: 42514:efhc1
uniprot id: A0A3B4C8U7
names: Subcellular Location Annotation
messages: cilium axoneme

42514:nol8
gene id: 42514:nol8
uniprot id: A0A3B4EN59
names: Subcellular Location Annotation
messages: nucleolus

42514:gstcd
gene id: 42514:gstcd
uniprot id: A0A3B4CQ60
names: Similarity
messages: Belongs to the GSTCD family.

42514:acss1
gene id: 42514:acss1
uniprot id: A0A3B4DT21
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:slc24a3
gene id: 42514:slc24a3
uniprot id: A0A3B4BW70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

42514:twsg1a
gene id: 42514:twsg1a
uniprot id: A0A3B4CDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

42514:chst14
gene id: 42514:chst14
uniprot id: A0A3B4BWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:dctn4
gene id: 42514:dctn4
uniprot id: A0A3B4E830
uniprot id: A0A3B4E8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunit 4 family.
messages: cell cortex
messages: centrosome
messages: sarcomere
messages: stress fiber

42514:aqp3b
gene id: 42514:aqp3b
uniprot id: A0A3B4E7L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

42514:st8sia5
gene id: 42514:st8sia5
uniprot id: A0A3B4CMJ8
uniprot id: A0A3B4E7E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:clic5a
gene id: 42514:clic5a
uniprot id: A0A3B4E973
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

42514:pou3f3a
gene id: 42514:pou3f3a
uniprot id: A0A3B4DMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

42514:hspa4a
gene id: 42514:hspa4a
uniprot id: A0A3B4D9D0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:lrrc8aa
gene id: 42514:lrrc8aa
uniprot id: A0A3B4CZ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

42514:lpxn
gene id: 42514:lpxn
uniprot id: A0A3B4E523
names: Subcellular Location Annotation
messages: cytoskeleton

42514:cand1
gene id: 42514:cand1
uniprot id: A0A3B4DB61
names: Similarity
messages: Belongs to the CAND family.

42514:yod1
gene id: 42514:yod1
uniprot id: A0A3B4C797
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Cleaves both polyubiquitin and di-ubiquitin.

42514:kcnk10b
gene id: 42514:kcnk10b
uniprot id: A0A3B4BSN6
uniprot id: A0A3B4BSP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:LOC108426952
gene id: 42514:LOC108426952
uniprot id: A0A3B4DRQ0
names: Similarity
messages: Belongs to the peptidase S28 family.

42514:dhrs7b
gene id: 42514:dhrs7b
uniprot id: A0A3B4C7Q8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:gpr137c
gene id: 42514:gpr137c
uniprot id: A0A3B4CBI0
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

42514:msx1b
gene id: 42514:msx1b
uniprot id: A0A3B4CHD5
names: Subcellular Location Annotation
messages: Nucleus

42514:mllt3
gene id: 42514:mllt3
uniprot id: A0A3B4CPW3
names: Subcellular Location Annotation
messages: Nucleus

42514:cept1a
gene id: 42514:cept1a
uniprot id: A0A3B4CEU4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

42514:LOC108425222
gene id: 42514:LOC108425222
uniprot id: A0A3B4BZT5
uniprot id: A0A3B4DPN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

42514:mzt1
gene id: 42514:mzt1
uniprot id: A0A3B4DRG6
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

42514:galnt6
gene id: 42514:galnt6
uniprot id: A0A3B4C726
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:LOC108411831
gene id: 42514:LOC108411831
uniprot id: A0A3B4CFI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

42514:tapt1b
gene id: 42514:tapt1b
uniprot id: A0A3B4BS61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

42514:gphnb
gene id: 42514:gphnb
uniprot id: A0A3B4C0S2
uniprot id: A0A3B4C423
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

42514:dtx3
gene id: 42514:dtx3
uniprot id: A0A3B4EI37
uniprot id: A0A3B4EID7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

42514:etf1a
gene id: 42514:etf1a
uniprot id: A0A3B4DRH3
uniprot id: A0A3B4DSZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

42514:srsf1b
gene id: 42514:srsf1b
uniprot id: A0A3B4CAR6
names: Similarity
messages: Belongs to the splicing factor SR family.

42514:st3gal7
gene id: 42514:st3gal7
uniprot id: A0A3B4ENF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:cebpg
gene id: 42514:cebpg
uniprot id: A0A3B4EEK4
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

42514:mab21l3
gene id: 42514:mab21l3
uniprot id: A0A3B4E871
names: Similarity
messages: Belongs to the mab-21 family.

42514:zgc:63587
gene id: 42514:zgc:63587
uniprot id: A0A3B4DJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

42514:hoxb2a
gene id: 42514:hoxb2a
uniprot id: A0A3B4E2E1
names: Subcellular Location Annotation
messages: Nucleus

42514:tbx3a
gene id: 42514:tbx3a
uniprot id: A0A3B4E4A9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:ubald2
gene id: 42514:ubald2
uniprot id: A0A3B4EER1
names: Similarity
messages: Belongs to the UBALD family.

42514:orc4
gene id: 42514:orc4
uniprot id: A0A3B4D1R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

42514:dtnbp1b
gene id: 42514:dtnbp1b
uniprot id: A0A3B4DBD5
names: Similarity
messages: Belongs to the dysbindin family.

42514:ipmka
gene id: 42514:ipmka
uniprot id: A0A3B4DGI2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

42514:reep3b
gene id: 42514:reep3b
uniprot id: A0A3B4CPY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

42514:nr4a2b
gene id: 42514:nr4a2b
uniprot id: A0A3B4E407
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

42514:rhot2
gene id: 42514:rhot2
uniprot id: A0A3B4DSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

42514:tent5aa
gene id: 42514:tent5aa
uniprot id: A0A3B4BY14
names: Similarity
messages: Belongs to the TENT family.

42514:polr2c
gene id: 42514:polr2c
uniprot id: A0A3B4C2D3
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

42514:sec22a
gene id: 42514:sec22a
uniprot id: A0A3B4EJ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

42514:LOC108413157
gene id: 42514:LOC108413157
uniprot id: A0A3B4BTD7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

42514:taf11
gene id: 42514:taf11
uniprot id: A0A3B4CXL3
names: Similarity
messages: Belongs to the TAF11 family.

42514:pnn
gene id: 42514:pnn
uniprot id: A0A3B4E5Q4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

42514:nadkb
gene id: 42514:nadkb
uniprot id: A0A3B4C015
names: Similarity
messages: Belongs to the NAD kinase family.

42514:ndufs8a
gene id: 42514:ndufs8a
uniprot id: A0A3B4CEK9
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

42514:cavin2a
gene id: 42514:cavin2a
uniprot id: A0A3B4D8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

42514:pabpc1a
gene id: 42514:pabpc1a
uniprot id: A0A3B4EPE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

42514:adnpa
gene id: 42514:adnpa
uniprot id: A0A3B4BUC2
names: Subcellular Location Annotation
messages: Nucleus

42514:fam193a
gene id: 42514:fam193a
uniprot id: A0A3B4CP52
names: Similarity
messages: Belongs to the FAM193 family.

42514:prickle2a
gene id: 42514:prickle2a
uniprot id: A0A3B4EHT5
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

42514:ogt.1
gene id: 42514:ogt.1
uniprot id: A0A3B4CP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

42514:rspo1
gene id: 42514:rspo1
uniprot id: A0A3B4DBG6
names: Similarity
messages: Belongs to the R-spondin family.

42514:psma4
gene id: 42514:psma4
uniprot id: A0A3B4DBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

42514:nmnat2
gene id: 42514:nmnat2
uniprot id: A0A3B4DRR5
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

42514:nr0b1
gene id: 42514:nr0b1
uniprot id: A0A3B4CAF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

42514:aldh3a2b
gene id: 42514:aldh3a2b
uniprot id: A0A3B4CCF7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

42514:mrpl16
gene id: 42514:mrpl16
uniprot id: A0A3B4DLW6
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

42514:LOC108435911
gene id: 42514:LOC108435911
uniprot id: A0A3B4C564
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:skila
gene id: 42514:skila
uniprot id: A0A3B4C037
names: Similarity
messages: Belongs to the SKI family.

42514:hcn3
gene id: 42514:hcn3
uniprot id: A0A3B4CGE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

42514:zgc:153293
gene id: 42514:zgc:153293
uniprot id: A0A3B4CIF1
names: Subcellular Location Annotation
messages: flagellum

42514:coro6
gene id: 42514:coro6
uniprot id: A0A3B4CBR5
names: Similarity
messages: Belongs to the WD repeat coronin family.

42514:psmb1
gene id: 42514:psmb1
uniprot id: A0A3B4D4U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

42514:LOC108439881
gene id: 42514:LOC108439881
uniprot id: A0A3B4EK13
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:polr3k
gene id: 42514:polr3k
uniprot id: A0A3B4C670
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

42514:LOC108410557
gene id: 42514:LOC108410557
uniprot id: A0A3B4CTR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

42514:nit1
gene id: 42514:nit1
uniprot id: A0A3B4E711
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

42514:tbl3
gene id: 42514:tbl3
uniprot id: A0A3B4CMJ7
names: Subcellular Location Annotation
messages: nucleolus

42514:LOC108425609
gene id: 42514:LOC108425609
uniprot id: A0A3B4CC92
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:slc7a7
gene id: 42514:slc7a7
uniprot id: A0A3B4C204
names: Subcellular Location Annotation
messages: Membrane

42514:kmt5b
gene id: 42514:kmt5b
uniprot id: A0A3B4DUN6
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

42514:LOC108428821
gene id: 42514:LOC108428821
uniprot id: A0A3B4DEY2
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

42514:cntnap2b
gene id: 42514:cntnap2b
uniprot id: A0A3B4C6Z4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

42514:taf12
gene id: 42514:taf12
uniprot id: A0A3B4CBK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

42514:LOC108442482
gene id: 42514:LOC108442482
uniprot id: A0A3B4DW74
names: Subcellular Location Annotation
messages: Cytoplasm

42514:pus1
gene id: 42514:pus1
uniprot id: A0A3B4EK11
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

42514:LOC108430398
gene id: 42514:LOC108430398
uniprot id: A0A3B4DDW0
names: Subcellular Location Annotation
messages: Nucleus

42514:spen
gene id: 42514:spen
uniprot id: A0A3B4EA51
names: Similarity
messages: Belongs to the RRM Spen family.

42514:ep300a
gene id: 42514:ep300a
uniprot id: A0A3B4E892
names: Subcellular Location Annotation
messages: Cytoplasm

42514:tafa4b
gene id: 42514:tafa4b
uniprot id: A0A3B4DZY8
names: Similarity
messages: Belongs to the TAFA family.

42514:LOC108416262
gene id: 42514:LOC108416262
uniprot id: A0A3B4CJX7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:c2h4orf48
gene id: 42514:c2h4orf48
uniprot id: A0A3B4EAH0
names: Subcellular Location Annotation
messages: Secreted

42514:sec61g
gene id: 42514:sec61g
uniprot id: A0A3B4CLX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:hoxa13b
gene id: 42514:hoxa13b
uniprot id: A0A3B4BSN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

42514:cops5
gene id: 42514:cops5
uniprot id: A0A3B4EDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

42514:LOC108436379
gene id: 42514:LOC108436379
uniprot id: A0A3B4C225
uniprot id: A0A3B4C5T4
names: Subcellular Location Annotation
messages: Nucleus

42514:nrxn1a
gene id: 42514:nrxn1a
uniprot id: A0A3B4DJ62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:get4
gene id: 42514:get4
uniprot id: A0A3B4DA22
names: Similarity
messages: Belongs to the GET4 family.

42514:slco4a1
gene id: 42514:slco4a1
uniprot id: A0A3B4DH23
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:zgc:101810
gene id: 42514:zgc:101810
uniprot id: A0A3B4C477
names: Similarity
messages: Belongs to the actin family.

42514:tspan5b
gene id: 42514:tspan5b
uniprot id: A0A3B4CD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:LOC108429936
gene id: 42514:LOC108429936
uniprot id: A0A3B4DBY3
names: Similarity
messages: Belongs to the S-100 family.

42514:pla2g12a
gene id: 42514:pla2g12a
uniprot id: A0A3B4C831
names: Subcellular Location Annotation
messages: Secreted

42514:prkg1a
gene id: 42514:prkg1a
uniprot id: A0A3B4END9
uniprot id: A0A3B4ERQ2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

42514:parvb
gene id: 42514:parvb
uniprot id: A0A3B4ELM9
names: Similarity
messages: Belongs to the parvin family.

42514:hapln4
gene id: 42514:hapln4
uniprot id: A0A3B4CU45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:zgc:110789
gene id: 42514:zgc:110789
uniprot id: A0A3B4CUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

42514:si:ch211-120k19.1
gene id: 42514:si:ch211-120k19.1
uniprot id: A0A3B4CNY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

42514:slc2a1b
gene id: 42514:slc2a1b
uniprot id: A0A3B4BYE8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:LOC108433700
gene id: 42514:LOC108433700
uniprot id: A0A3B4C455
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

42514:mettl16
gene id: 42514:mettl16
uniprot id: A0A3B4BVW9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

42514:si:ch73-383l1.1
gene id: 42514:si:ch73-383l1.1
uniprot id: A0A3B4EKH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

42514:mrpl41
gene id: 42514:mrpl41
uniprot id: A0A3B4CUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

42514:thyn1
gene id: 42514:thyn1
uniprot id: A0A3B4C6Z0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

42514:cnot8
gene id: 42514:cnot8
uniprot id: A0A3B4CIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

42514:mutyh
gene id: 42514:mutyh
uniprot id: A0A3B4E433
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

42514:ckba
gene id: 42514:ckba
uniprot id: A0A3B4ENX5
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

42514:upf3b
gene id: 42514:upf3b
uniprot id: A0A3B4CVQ8
names: Similarity
messages: Belongs to the RENT3 family.

42514:rpl8
gene id: 42514:rpl8
uniprot id: A0A3B4CUV8
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

42514:ccdc65
gene id: 42514:ccdc65
uniprot id: A0A3B4BX71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC1 family.
messages: cilium axoneme
messages: flagellum axoneme

42514:LOC108424370
gene id: 42514:LOC108424370
uniprot id: A0A3B4EAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:kif15
gene id: 42514:kif15
uniprot id: A0A3B4DLZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.
messages: spindle

42514:lcat
gene id: 42514:lcat
uniprot id: A0A3B4C0Z9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

42514:LOC108424607
gene id: 42514:LOC108424607
uniprot id: A0A3B4DIP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:mrps27
gene id: 42514:mrps27
uniprot id: A0A3B4DJ02
names: Subcellular Location Annotation
messages: Mitochondrion

42514:rps6ka1
gene id: 42514:rps6ka1
uniprot id: A0A3B4BR94
uniprot id: A0A3B4BRC4
uniprot id: A0A3B4BRC8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

42514:crx
gene id: 42514:crx
uniprot id: A0A3B4C397
names: Subcellular Location Annotation
messages: Nucleus

42514:panx1a
gene id: 42514:panx1a
uniprot id: A0A3B4E828
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

42514:eomesa
gene id: 42514:eomesa
uniprot id: A0A3B4C6Y0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:si:ch73-257c13.2
gene id: 42514:si:ch73-257c13.2
uniprot id: A0A3B4BU13
names: Similarity
messages: Belongs to the HARBI1 family.

42514:slc10a1
gene id: 42514:slc10a1
uniprot id: A0A3B4DNM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

42514:upp2
gene id: 42514:upp2
uniprot id: A0A3B4DYQ4
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

42514:si:ch211-63o20.7
gene id: 42514:si:ch211-63o20.7
uniprot id: A0A3B4DG25
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:slc39a10
gene id: 42514:slc39a10
uniprot id: A0A3B4EN42
names: Subcellular Location Annotation
messages: Membrane

42514:adgra2
gene id: 42514:adgra2
uniprot id: A0A3B4CM14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

42514:LOC108428958
gene id: 42514:LOC108428958
uniprot id: A0A3B4EDL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

42514:LOC108433277
gene id: 42514:LOC108433277
uniprot id: A0A3B4DC38
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

42514:jupa
gene id: 42514:jupa
uniprot id: A0A3B4DU53
names: Similarity
messages: Belongs to the beta-catenin family.

42514:ca6
gene id: 42514:ca6
uniprot id: A0A3B4CR56
names: Caution
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:masp1
gene id: 42514:masp1
uniprot id: A0A3B4D0U9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108434377
gene id: 42514:LOC108434377
uniprot id: A0A3B4DGX7
names: Subcellular Location Annotation
messages: Membrane

42514:nek8
gene id: 42514:nek8
uniprot id: A0A3B4CAS1
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

42514:crygs3
gene id: 42514:crygs3
uniprot id: A0A3B4CFY0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:fam126a
gene id: 42514:fam126a
uniprot id: A0A3B4E6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

42514:tpd52l2a
gene id: 42514:tpd52l2a
uniprot id: A0A3B4BRL6
uniprot id: A0A3B4DMN6
names: Similarity
messages: Belongs to the TPD52 family.

42514:wnt2
gene id: 42514:wnt2
uniprot id: A0A3B4CAW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:lmod1b
gene id: 42514:lmod1b
uniprot id: A0A3B4CD84
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

42514:zgc:86598
gene id: 42514:zgc:86598
uniprot id: A0A3B4BSW3
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:fam114a1
gene id: 42514:fam114a1
uniprot id: A0A3B4CG70
names: Similarity
messages: Belongs to the FAM114 family.

42514:LOC108412723
gene id: 42514:LOC108412723
uniprot id: A0A3B4D930
names: Similarity
messages: Belongs to the synuclein family.

42514:LOC108416588
gene id: 42514:LOC108416588
uniprot id: A0A3B4BTX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:tnfrsf9a
gene id: 42514:tnfrsf9a
uniprot id: A0A3B4E9I0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dgcr2
gene id: 42514:dgcr2
uniprot id: A0A3B4CGD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:prkaa1
gene id: 42514:prkaa1
uniprot id: A0A3B4ELK3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

42514:higd2a
gene id: 42514:higd2a
uniprot id: A0A3B4C4K1
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

42514:scp2a
gene id: 42514:scp2a
uniprot id: A0A3B4CN23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Cytoplasm
messages: Mitochondrion

42514:tspan17
gene id: 42514:tspan17
uniprot id: A0A3B4CNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:edn1
gene id: 42514:edn1
uniprot id: A0A3B4BSR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

42514:LOC108439812
gene id: 42514:LOC108439812
uniprot id: A0A3B4DPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

42514:dhx8
gene id: 42514:dhx8
uniprot id: A0A3B4BTP9
names: Subcellular Location Annotation
messages: Nucleus

42514:ppp3ca
gene id: 42514:ppp3ca
uniprot id: A0A3B4C6Y7
uniprot id: A0A3B4C7K1
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

42514:pde10a
gene id: 42514:pde10a
uniprot id: A0A3B4D926
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:reep5
gene id: 42514:reep5
uniprot id: A0A3B4CWS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

42514:LOC108434137
gene id: 42514:LOC108434137
uniprot id: A0A3B4DVN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:atg9a
gene id: 42514:atg9a
uniprot id: A0A3B4C6F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

42514:lpcat3
gene id: 42514:lpcat3
uniprot id: A0A3B4CQV8
names: Subcellular Location Annotation
messages: Membrane

42514:foxa
gene id: 42514:foxa
uniprot id: A0A3B4CTF5
names: Subcellular Location Annotation
messages: Nucleus

42514:tgfbr2b
gene id: 42514:tgfbr2b
uniprot id: A0A3B4DPC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

42514:emx3
gene id: 42514:emx3
uniprot id: A0A3B4EIW4
names: Subcellular Location Annotation
messages: Nucleus

42514:cct2
gene id: 42514:cct2
uniprot id: A0A3B4DDV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

42514:msh2
gene id: 42514:msh2
uniprot id: A0A3B4DMJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

42514:acsf2
gene id: 42514:acsf2
uniprot id: A0A3B4DXQ7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:trnt1
gene id: 42514:trnt1
uniprot id: A0A3B4DKG5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

42514:LOC108414326
gene id: 42514:LOC108414326
uniprot id: A0A3B4BKI8
names: Similarity
messages: Belongs to the MHC class I family.

42514:ndufb3
gene id: 42514:ndufb3
uniprot id: A0A3B4BM04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

42514:mycla
gene id: 42514:mycla
uniprot id: A0A3B4BZM6
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

42514:LOC108438897
gene id: 42514:LOC108438897
uniprot id: A0A3B4EEF1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:wu:fa11c10
gene id: 42514:wu:fa11c10
uniprot id: A0A3B4C6A2
names: Similarity
messages: Belongs to the FAM110 family.

42514:ccne2
gene id: 42514:ccne2
uniprot id: A0A3B4CZX7
names: Similarity
messages: Belongs to the cyclin family.

42514:ncoa2
gene id: 42514:ncoa2
uniprot id: A0A3B4EI31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

42514:svopa
gene id: 42514:svopa
uniprot id: A0A3B4C3I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

42514:arl6
gene id: 42514:arl6
uniprot id: A0A3B4D2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

42514:slc35a5
gene id: 42514:slc35a5
uniprot id: A0A3B4D214
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:slc2a11a
gene id: 42514:slc2a11a
uniprot id: A0A3B4E419
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:ess2
gene id: 42514:ess2
uniprot id: A0A3B4DZ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

42514:atl2
gene id: 42514:atl2
uniprot id: A0A3B4EQ30
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

42514:LOC108412385
gene id: 42514:LOC108412385
uniprot id: A0A3B4DQM5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:clstn3
gene id: 42514:clstn3
uniprot id: A0A3B4E5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

42514:LOC108414923
gene id: 42514:LOC108414923
uniprot id: A0A3B4C1H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

42514:cryl1
gene id: 42514:cryl1
uniprot id: A0A3B4BZ40
uniprot id: A0A3B4BZ67
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

42514:LOC108414952
gene id: 42514:LOC108414952
uniprot id: A0A3B4DRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

42514:mpp5b
gene id: 42514:mpp5b
uniprot id: A0A3B4C4P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: tight junction

42514:magi2a
gene id: 42514:magi2a
uniprot id: A0A3B4DNR8
names: Subcellular Location Annotation
messages: Membrane

42514:sypl2a
gene id: 42514:sypl2a
uniprot id: A0A3B4CIP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

42514:vasna
gene id: 42514:vasna
uniprot id: A0A3B4CRW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:zgc:64002
gene id: 42514:zgc:64002
uniprot id: A0A3B4E525
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

42514:cd37
gene id: 42514:cd37
uniprot id: A0A3B4BPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:aldh8a1
gene id: 42514:aldh8a1
uniprot id: A0A3B4D8R0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

42514:nsdhl
gene id: 42514:nsdhl
uniprot id: A0A3B4CPK9
names: Similarity
messages: Belongs to the 3-beta-HSD family.

42514:ccdc86
gene id: 42514:ccdc86
uniprot id: A0A3B4DMU6
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108412669
gene id: 42514:LOC108412669
uniprot id: A0A3B4CKD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

42514:LOC108443155
gene id: 42514:LOC108443155
uniprot id: A0A3B4BXH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

42514:celsr1b
gene id: 42514:celsr1b
uniprot id: A0A3B4CTJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

42514:ndufa1
gene id: 42514:ndufa1
uniprot id: A0A3B4CY12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

42514:tmpob
gene id: 42514:tmpob
uniprot id: A0A3B4DHG1
names: Similarity
messages: Belongs to the LEM family.

42514:sae1
gene id: 42514:sae1
uniprot id: A0A3B4DP64
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

42514:dvl2
gene id: 42514:dvl2
uniprot id: A0A3B4EKS7
names: Similarity
messages: Belongs to the DSH family.

42514:LOC108436679
gene id: 42514:LOC108436679
uniprot id: A0A3B4EIP8
names: Similarity
messages: Belongs to the apolipoprotein L family.

42514:tmem201
gene id: 42514:tmem201
uniprot id: A0A3B4CYB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

42514:capn2a
gene id: 42514:capn2a
uniprot id: A0A3B4CL91
names: Similarity
messages: Belongs to the peptidase C2 family.

42514:psma5
gene id: 42514:psma5
uniprot id: A0A3B4CJP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

42514:fto
gene id: 42514:fto
uniprot id: A0A3B4D4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

42514:tdrd7a
gene id: 42514:tdrd7a
uniprot id: A0A3B4CV00
names: Subcellular Location Annotation
messages: Cytoplasm

42514:si:ch211-106h11.3
gene id: 42514:si:ch211-106h11.3
uniprot id: A0A3B4CAK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:LOC108437174
gene id: 42514:LOC108437174
uniprot id: A0A3B4EML7
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

42514:etv6
gene id: 42514:etv6
uniprot id: A0A3B4BQX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:eif3i
gene id: 42514:eif3i
uniprot id: A0A3B4DDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

42514:hexdc
gene id: 42514:hexdc
uniprot id: A0A3B4EDP4
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

42514:pdp2
gene id: 42514:pdp2
uniprot id: A0A3B4D1I3
names: Similarity
messages: Belongs to the PP2C family.

42514:LOC108430260
gene id: 42514:LOC108430260
uniprot id: A0A3B4BSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

42514:oprm1
gene id: 42514:oprm1
uniprot id: A0A3B4EQE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

42514:soul2
gene id: 42514:soul2
uniprot id: A0A3B4BT84
names: Similarity
messages: Belongs to the HEBP family.

42514:LOC108413244
gene id: 42514:LOC108413244
uniprot id: A0A3B4BRZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

42514:glud1b
gene id: 42514:glud1b
uniprot id: A0A3B4BY26
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

42514:dyrk3
gene id: 42514:dyrk3
uniprot id: A0A3B4C0H0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

42514:tinagl1
gene id: 42514:tinagl1
uniprot id: A0A3B4EN87
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:lsm8
gene id: 42514:lsm8
uniprot id: A0A3B4BZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

42514:ptpn22
gene id: 42514:ptpn22
uniprot id: A0A3B4C734
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.

42514:gria4b
gene id: 42514:gria4b
uniprot id: A0A3B4CIL8
uniprot id: A0A3B4E4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:casp2
gene id: 42514:casp2
uniprot id: A0A3B4CQD3
uniprot id: A0A3B4CSF2
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:kat7b
gene id: 42514:kat7b
uniprot id: A0A3B4DFD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

42514:pxmp2
gene id: 42514:pxmp2
uniprot id: A0A3B4DNB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

42514:uvssa
gene id: 42514:uvssa
uniprot id: A0A3B4CNA5
names: Similarity
messages: Belongs to the UVSSA family.

42514:prf1.5
gene id: 42514:prf1.5
uniprot id: A0A3B4BZ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

42514:acss3
gene id: 42514:acss3
uniprot id: A0A3B4C7T3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:ugdh
gene id: 42514:ugdh
uniprot id: A0A3B4DAP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

42514:LOC108423901
gene id: 42514:LOC108423901
uniprot id: A0A3B4CDD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

42514:si:ch73-374l24.1
gene id: 42514:si:ch73-374l24.1
uniprot id: A0A3B4EP19
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane

42514:chd8
gene id: 42514:chd8
uniprot id: A0A3B4CVH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. CHD8 subfamily.
messages: Component of some MLL1/MLL complex.
messages: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. May also act as a transcription activator by participating in efficient U6 RNA polymerase III transcription.
messages: Nucleus

42514:svilc
gene id: 42514:svilc
uniprot id: A0A3B4BQZ2
names: Similarity
messages: Belongs to the villin/gelsolin family.

42514:dcp1a
gene id: 42514:dcp1a
uniprot id: A0A3B4DSY1
names: Similarity
messages: Belongs to the DCP1 family.

42514:mycn
gene id: 42514:mycn
uniprot id: A0A3B4CJ11
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

42514:trim32
gene id: 42514:trim32
uniprot id: A0A3B4ECS8
names: Similarity
messages: Belongs to the TRIM/RBCC family.

42514:rbm5
gene id: 42514:rbm5
uniprot id: A0A3B4C553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

42514:slc7a10b
gene id: 42514:slc7a10b
uniprot id: A0A3B4CI34
names: Subcellular Location Annotation
messages: Membrane

42514:ism2b
gene id: 42514:ism2b
uniprot id: A0A3B4BNV8
names: Similarity
messages: Belongs to the isthmin family.

42514:LOC108412682
gene id: 42514:LOC108412682
uniprot id: A0A3B4ENC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

42514:dkc1
gene id: 42514:dkc1
uniprot id: A0A3B4BVW4
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

42514:iqcg
gene id: 42514:iqcg
uniprot id: A0A3B4DEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC9 family.
messages: flagellum
messages: flagellum axoneme

42514:csk
gene id: 42514:csk
uniprot id: A0A3B4CTE4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:numb
gene id: 42514:numb
uniprot id: A0A3B4DNU1
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

42514:LOC108425947
gene id: 42514:LOC108425947
uniprot id: A0A3B4DBK5
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:golga5
gene id: 42514:golga5
uniprot id: A0A3B4C9V7
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

42514:rb1
gene id: 42514:rb1
uniprot id: A0A3B4CBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

42514:smdt1b
gene id: 42514:smdt1b
uniprot id: A0A3B4CE75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

42514:srp9
gene id: 42514:srp9
uniprot id: A0A3B4DLE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

42514:ndufaf1
gene id: 42514:ndufaf1
uniprot id: A0A3B4C7Y9
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

42514:LOC108430900
gene id: 42514:LOC108430900
uniprot id: A0A3B4C6D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

42514:fbp1b
gene id: 42514:fbp1b
uniprot id: A0A3B4CTT9
names: Similarity
messages: Belongs to the FBPase class 1 family.

42514:aldh1l1
gene id: 42514:aldh1l1
uniprot id: A0A3B4DDQ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

42514:gtf2a1
gene id: 42514:gtf2a1
uniprot id: A0A3B4BN47
uniprot id: A0A3B4BQZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

42514:napepld
gene id: 42514:napepld
uniprot id: A0A3B4DZQ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPE-PLD family.
messages: Binds 2 zinc divalent cations per subunit.
messages: Homodimer. Bile acids promote the assembly of inactive monomers into an active dimer and enable catalysis.
messages: Nucleus envelope

42514:LOC108427363
gene id: 42514:LOC108427363
uniprot id: A0A3B4E7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
messages: Nucleus

42514:si:ch211-195b15.7
gene id: 42514:si:ch211-195b15.7
uniprot id: A0A3B4E7K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

42514:inpp4ab
gene id: 42514:inpp4ab
uniprot id: A0A3B4EAR1
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

42514:ago3b
gene id: 42514:ago3b
uniprot id: A0A3B4BS12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

42514:ncln
gene id: 42514:ncln
uniprot id: A0A3B4BX35
names: Similarity
messages: Belongs to the nicastrin family.

42514:slco5a1a
gene id: 42514:slco5a1a
uniprot id: A0A3B4E940
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:acadsb
gene id: 42514:acadsb
uniprot id: A0A3B4E421
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

42514:p2ry1
gene id: 42514:p2ry1
uniprot id: A0A3B4CMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:gmnn
gene id: 42514:gmnn
uniprot id: A0A3B4BYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

42514:snrpe
gene id: 42514:snrpe
uniprot id: A0A3B4C772
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

42514:sft2d3
gene id: 42514:sft2d3
uniprot id: A0A3B4C0Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

42514:LOC108440485
gene id: 42514:LOC108440485
uniprot id: A0A3B4EHH5
names: Similarity
messages: Belongs to the FAM124 family.

42514:fxr2
gene id: 42514:fxr2
uniprot id: A0A3B4C9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule

42514:cdk5r1b
gene id: 42514:cdk5r1b
uniprot id: A0A3B4DK52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

42514:prmt3
gene id: 42514:prmt3
uniprot id: A0A3B4D5L5
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108415447
gene id: 42514:LOC108415447
uniprot id: A0A3B4DDF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:LOC108432397
gene id: 42514:LOC108432397
uniprot id: A0A3B4C9M6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:slc6a1a
gene id: 42514:slc6a1a
uniprot id: A0A3B4ECC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:LOC108438832
gene id: 42514:LOC108438832
uniprot id: A0A3B4D983
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

42514:LOC108425092
gene id: 42514:LOC108425092
uniprot id: A0A3B4CLG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

42514:si:dkey-202l22.3
gene id: 42514:si:dkey-202l22.3
uniprot id: A0A3B4CYQ4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:htra4
gene id: 42514:htra4
uniprot id: A0A3B4BW42
names: Similarity
messages: Belongs to the peptidase S1C family.

42514:eif4ebp3
gene id: 42514:eif4ebp3
uniprot id: A0A3B4BZN4
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

42514:slc6a11b
gene id: 42514:slc6a11b
uniprot id: A0A3B4BU30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:cacng5a
gene id: 42514:cacng5a
uniprot id: A0A3B4DG21
uniprot id: A0A3B4DG33
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

42514:tmem237b
gene id: 42514:tmem237b
uniprot id: A0A3B4CWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

42514:nf2b
gene id: 42514:nf2b
uniprot id: A0A3B4E1Z8
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

42514:dpys
gene id: 42514:dpys
uniprot id: A0A3B4BWM2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

42514:grhl1
gene id: 42514:grhl1
uniprot id: A0A3B4EEI7
names: Subcellular Location Annotation
messages: Nucleus

42514:dennd6b
gene id: 42514:dennd6b
uniprot id: A0A3B4DNF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

42514:ca4a
gene id: 42514:ca4a
uniprot id: A0A3B4CTJ1
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

42514:LOC108426548
gene id: 42514:LOC108426548
uniprot id: A0A3B4D1G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: dendrite

42514:ube2r2
gene id: 42514:ube2r2
uniprot id: A0A3B4D0X0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:sntg1
gene id: 42514:sntg1
uniprot id: A0A3B4CHT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

42514:LOC108423545
gene id: 42514:LOC108423545
uniprot id: A0A3B4DHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

42514:ap1s1
gene id: 42514:ap1s1
uniprot id: A0A3B4EHR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

42514:si:dkeyp-69e1.8
gene id: 42514:si:dkeyp-69e1.8
uniprot id: A0A3B4D3W1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:chga
gene id: 42514:chga
uniprot id: A0A3B4DLP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

42514:serpinf2b
gene id: 42514:serpinf2b
uniprot id: A0A3B4BU14
names: Similarity
messages: Belongs to the serpin family.

42514:kdm4b
gene id: 42514:kdm4b
uniprot id: A0A3B4D2V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

42514:pfkfb2b
gene id: 42514:pfkfb2b
uniprot id: A0A3B4C5K6
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

42514:tex261
gene id: 42514:tex261
uniprot id: A0A3B4EL82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

42514:h3f3a
gene id: 42514:h3f3a
uniprot id: A0A3B4BZQ6
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:si:ch211-201h21.5
gene id: 42514:si:ch211-201h21.5
uniprot id: A0A3B4EK92
names: Similarity
messages: Belongs to the IUNH family.

42514:LOC108430216
gene id: 42514:LOC108430216
uniprot id: A0A3B4C3P1
names: Subcellular Location Annotation
messages: Membrane

42514:loxl2a
gene id: 42514:loxl2a
uniprot id: A0A3B4D3Z8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

42514:rps6ka4
gene id: 42514:rps6ka4
uniprot id: A0A3B4CYZ4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

42514:adam12
gene id: 42514:adam12
uniprot id: A0A3B4EE65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:si:dkey-35i13.1
gene id: 42514:si:dkey-35i13.1
uniprot id: A0A3B4C3E4
names: Subcellular Location Annotation
messages: Membrane

42514:kdm4c
gene id: 42514:kdm4c
uniprot id: A0A3B4E7C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

42514:popdc2
gene id: 42514:popdc2
uniprot id: A0A3B4C135
names: Similarity
messages: Belongs to the popeye family.

42514:marcksl1a
gene id: 42514:marcksl1a
uniprot id: A0A3B4C3J7
names: Similarity
messages: Belongs to the MARCKS family.

42514:tm9sf3
gene id: 42514:tm9sf3
uniprot id: A0A3B4DSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

42514:LOC108436550
gene id: 42514:LOC108436550
uniprot id: A0A3B4DKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:riox2
gene id: 42514:riox2
uniprot id: A0A3B4E7D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

42514:coq7
gene id: 42514:coq7
uniprot id: A0A3B4DWH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

42514:ddrgk1
gene id: 42514:ddrgk1
uniprot id: A0A3B4DAG4
names: Similarity
messages: Belongs to the DDRGK1 family.

42514:gipc2
gene id: 42514:gipc2
uniprot id: A0A3B4E653
names: Similarity
messages: Belongs to the GIPC family.

42514:glg1a
gene id: 42514:glg1a
uniprot id: A0A3B4CET0
uniprot id: A0A3B4CJ03
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

42514:txlnbb
gene id: 42514:txlnbb
uniprot id: A0A3B4BL24
names: Similarity
messages: Belongs to the taxilin family.

42514:tlcd4a
gene id: 42514:tlcd4a
uniprot id: A0A3B4CXB6
names: Subcellular Location Annotation
messages: Membrane

42514:zgc:172076
gene id: 42514:zgc:172076
uniprot id: A0A3B4DSR3
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:gpr171
gene id: 42514:gpr171
uniprot id: A0A3B4BYZ2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108424720
gene id: 42514:LOC108424720
uniprot id: A0A3B4DIU6
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

42514:LOC108439227
gene id: 42514:LOC108439227
uniprot id: A0A3B4C2B0
names: Subcellular Location Annotation
messages: Membrane

42514:ap3b1a
gene id: 42514:ap3b1a
uniprot id: A0A3B4DAZ1
uniprot id: A0A3B4DCA8
uniprot id: A0A3B4DCE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

42514:ttyh2l
gene id: 42514:ttyh2l
uniprot id: A0A3B4EDZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

42514:tmco3
gene id: 42514:tmco3
uniprot id: A0A3B4C2D1
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108433586
gene id: 42514:LOC108433586
uniprot id: A0A3B4E129
names: Similarity
messages: Belongs to the ZC3H12 family.

42514:evx2
gene id: 42514:evx2
uniprot id: A0A3B4ECL1
names: Subcellular Location Annotation
messages: Nucleus

42514:chac2
gene id: 42514:chac2
uniprot id: A0A3B4EJC0
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

42514:LOC108426478
gene id: 42514:LOC108426478
uniprot id: A0A3B4ELJ7
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

42514:mccc2
gene id: 42514:mccc2
uniprot id: A0A3B4CB09
names: Similarity
messages: Belongs to the AccD/PCCB family.

42514:zgc:77439
gene id: 42514:zgc:77439
uniprot id: A0A3B4D8Q9
names: Similarity
messages: Belongs to the FMO family.

42514:wdr44
gene id: 42514:wdr44
uniprot id: A0A3B4CZZ3
names: Subcellular Location Annotation
messages: trans-Golgi network

42514:imp3
gene id: 42514:imp3
uniprot id: A0A3B4CLN8
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

42514:si:cabz01101003.1
gene id: 42514:si:cabz01101003.1
uniprot id: A0A3B4CZG4
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

42514:ciapin1
gene id: 42514:ciapin1
uniprot id: A0A3B4DTP7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

42514:best1
gene id: 42514:best1
uniprot id: A0A3B4D0A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

42514:gabarapb
gene id: 42514:gabarapb
uniprot id: A0A3B4C1C1
names: Similarity
messages: Belongs to the ATG8 family.

42514:sgsm2
gene id: 42514:sgsm2
uniprot id: A0A3B4BY70
uniprot id: A0A3B4C160
names: Similarity
messages: Belongs to the RUTBC family.

42514:mstna
gene id: 42514:mstna
uniprot id: A0A3B4E933
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

42514:oxct1a
gene id: 42514:oxct1a
uniprot id: A0A3B4BP26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

42514:ube2f
gene id: 42514:ube2f
uniprot id: A0A3B4CYF6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:csrnp1b
gene id: 42514:csrnp1b
uniprot id: A0A3B4E802
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

42514:LOC108432821
gene id: 42514:LOC108432821
uniprot id: A0A3B4CWL3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:mmp28
gene id: 42514:mmp28
uniprot id: A0A3B4BUT2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

42514:bsx
gene id: 42514:bsx
uniprot id: A0A3B4CSD0
names: Subcellular Location Annotation
messages: Nucleus

42514:churc1
gene id: 42514:churc1
uniprot id: A0A3B4C851
names: Similarity
messages: Belongs to the Churchill family.

42514:tbx18
gene id: 42514:tbx18
uniprot id: A0A3B4EGL6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:LOC108430898
gene id: 42514:LOC108430898
uniprot id: A0A3B4C540
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:slc44a5a
gene id: 42514:slc44a5a
uniprot id: A0A3B4DD94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

42514:rorca
gene id: 42514:rorca
uniprot id: A0A3B4C2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:slc44a1a
gene id: 42514:slc44a1a
uniprot id: A0A3B4CES0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

42514:dlg5a
gene id: 42514:dlg5a
uniprot id: A0A3B4ENK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cytoplasm

42514:LOC108431845
gene id: 42514:LOC108431845
uniprot id: A0A3B4E2K6
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:crygn1
gene id: 42514:crygn1
uniprot id: A0A3B4EHK5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:LOC108438711
gene id: 42514:LOC108438711
uniprot id: A0A3B4BSD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

42514:LOC108432015
gene id: 42514:LOC108432015
uniprot id: A0A3B4DN95
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

42514:si:dkey-206d17.12
gene id: 42514:si:dkey-206d17.12
uniprot id: A0A3B4C1G8
names: Similarity
messages: Belongs to the ZC3H12 family.

42514:tlcd3ba
gene id: 42514:tlcd3ba
uniprot id: A0A3B4CQ48
names: Subcellular Location Annotation
messages: Membrane

42514:calb2a
gene id: 42514:calb2a
uniprot id: A0A3B4C3I0
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

42514:fen1
gene id: 42514:fen1
uniprot id: A0A3B4DB77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Mitochondrion
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

42514:pan3
gene id: 42514:pan3
uniprot id: A0A3B4EJC2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

42514:c23h9orf78
gene id: 42514:c23h9orf78
uniprot id: A0A3B4EQB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TLS1 family.
messages: Nucleus

42514:mycb
gene id: 42514:mycb
uniprot id: A0A3B4D5H7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

42514:zgc:91976
gene id: 42514:zgc:91976
uniprot id: A0A3B4C9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

42514:cpt1aa
gene id: 42514:cpt1aa
uniprot id: A0A3B4E377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:hmgcs1
gene id: 42514:hmgcs1
uniprot id: A0A3B4CV79
uniprot id: A0A3B4CVB9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

42514:slc6a8
gene id: 42514:slc6a8
uniprot id: A0A3B4D4G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:LOC108432124
gene id: 42514:LOC108432124
uniprot id: A0A3B4DFB2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:exoc3l2b
gene id: 42514:exoc3l2b
uniprot id: A0A3B4BXC5
names: Similarity
messages: Belongs to the SEC6 family.

42514:plp1a
gene id: 42514:plp1a
uniprot id: A0A3B4CM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

42514:ephb2a
gene id: 42514:ephb2a
uniprot id: A0A3B4E8J6
names: Subcellular Location Annotation
messages: Membrane

42514:fibinb
gene id: 42514:fibinb
uniprot id: A0A3B4CCZ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

42514:LOC108442278
gene id: 42514:LOC108442278
uniprot id: A0A3B4DJ33
names: Similarity
messages: Belongs to the DDIT4 family.

42514:LOC108414084
gene id: 42514:LOC108414084
uniprot id: A0A3B4BP39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

42514:wu:fl23c11
gene id: 42514:wu:fl23c11
uniprot id: A0A3B4DJN6
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108424220
gene id: 42514:LOC108424220
uniprot id: A0A3B4D6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

42514:p4ha1b
gene id: 42514:p4ha1b
uniprot id: A0A3B4CXW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

42514:elk1
gene id: 42514:elk1
uniprot id: A0A3B4EII0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:shank3a
gene id: 42514:shank3a
uniprot id: A0A3B4D4P8
uniprot id: A0A3B4EE29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cytoplasm
messages: Postsynaptic density

42514:ubn2b
gene id: 42514:ubn2b
uniprot id: A0A3B4CLW7
names: Similarity
messages: Belongs to the ubinuclein family.

42514:LOC108443055
gene id: 42514:LOC108443055
uniprot id: A0A3B4C8V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

42514:bscl2l
gene id: 42514:bscl2l
uniprot id: A0A3B4DBJ8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:pthlhb
gene id: 42514:pthlhb
uniprot id: A0A3B4DGG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

42514:ddias
gene id: 42514:ddias
uniprot id: A0A3B4E012
names: Similarity
messages: Belongs to the replication factor A protein 1 family.

42514:acsl6
gene id: 42514:acsl6
uniprot id: A0A3B4CET8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

42514:clec16a
gene id: 42514:clec16a
uniprot id: A0A3B4C4M4
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

42514:LOC108424343
gene id: 42514:LOC108424343
uniprot id: A0A3B4ECB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

42514:gmds
gene id: 42514:gmds
uniprot id: A0A3B4D168
uniprot id: A0A3B4EHS5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

42514:pla1a
gene id: 42514:pla1a
uniprot id: A0A3B4C175
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

42514:slc5a7a
gene id: 42514:slc5a7a
uniprot id: A0A3B4EHC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:capn12
gene id: 42514:capn12
uniprot id: A0A3B4E7C8
names: Similarity
messages: Belongs to the peptidase C2 family.

42514:slc7a1a
gene id: 42514:slc7a1a
uniprot id: A0A3B4D4W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

42514:ckmt1
gene id: 42514:ckmt1
uniprot id: A0A3B4CVT4
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

42514:LOC108426645
gene id: 42514:LOC108426645
uniprot id: A0A3B4D947
names: Similarity
messages: Belongs to the mab-21 family.

42514:fuz
gene id: 42514:fuz
uniprot id: A0A3B4DV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fuzzy family.
messages: cytoskeleton

42514:si:ch211-232m10.6
gene id: 42514:si:ch211-232m10.6
uniprot id: A0A3B4D7L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

42514:grin2ca
gene id: 42514:grin2ca
uniprot id: A0A3B4D4W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

42514:rdh10a
gene id: 42514:rdh10a
uniprot id: A0A3B4D1D1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:rpp30
gene id: 42514:rpp30
uniprot id: A0A3B4E0U5
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

42514:polr2a
gene id: 42514:polr2a
uniprot id: A0A3B4C1X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

42514:myoz1b
gene id: 42514:myoz1b
uniprot id: A0A3B4DP28
names: Similarity
messages: Belongs to the myozenin family.

42514:slc49a3
gene id: 42514:slc49a3
uniprot id: A0A3B4DCP1
names: Subcellular Location Annotation
messages: Membrane

42514:nagk
gene id: 42514:nagk
uniprot id: A0A3B4DQD0
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

42514:abcg8
gene id: 42514:abcg8
uniprot id: A0A3B4C8T8
names: Subcellular Location Annotation
messages: Membrane

42514:blvra
gene id: 42514:blvra
uniprot id: A0A3B4D823
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.
messages: Monomer.
messages: Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
messages: cytosol

42514:sgms2a
gene id: 42514:sgms2a
uniprot id: A0A3B4CPZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

42514:rap2c
gene id: 42514:rap2c
uniprot id: A0A3B4DJT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

42514:mylkb
gene id: 42514:mylkb
uniprot id: A0A3B4ED00
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

42514:LOC108429255
gene id: 42514:LOC108429255
uniprot id: A0A3B4DQX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

42514:tspan12
gene id: 42514:tspan12
uniprot id: A0A3B4DQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:LOC108428404
gene id: 42514:LOC108428404
uniprot id: A0A3B4CK16
names: Subcellular Location Annotation
messages: Nucleus

42514:vps37a
gene id: 42514:vps37a
uniprot id: A0A3B4DS80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

42514:snx7
gene id: 42514:snx7
uniprot id: A0A3B4EBW5
names: Similarity
messages: Belongs to the sorting nexin family.

42514:atp1b2b
gene id: 42514:atp1b2b
uniprot id: A0A3B4CAK9
uniprot id: A0A3B4DYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

42514:cpm
gene id: 42514:cpm
uniprot id: A0A3B4BWB5
names: Similarity
messages: Belongs to the peptidase M14 family.

42514:elavl2
gene id: 42514:elavl2
uniprot id: A0A3B4DFZ6
names: Similarity
messages: Belongs to the RRM elav family.

42514:LOC108440021
gene id: 42514:LOC108440021
uniprot id: A0A3B4CWL4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:nrxn3b
gene id: 42514:nrxn3b
uniprot id: A0A3B4EIN7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:slc35e4
gene id: 42514:slc35e4
uniprot id: A0A3B4BWI2
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108441939
gene id: 42514:LOC108441939
uniprot id: A0A3B4DTH0
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

42514:LOC108432943
gene id: 42514:LOC108432943
uniprot id: A0A3B4CSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

42514:stk33
gene id: 42514:stk33
uniprot id: A0A3B4CF66
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108439955
gene id: 42514:LOC108439955
uniprot id: A0A3B4EJ75
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

42514:si:ch211-79m20.1
gene id: 42514:si:ch211-79m20.1
uniprot id: A0A3B4EL63
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

42514:rpl30
gene id: 42514:rpl30
uniprot id: A0A3B4C368
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

42514:lasp1
gene id: 42514:lasp1
uniprot id: A0A3B4DVU7
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

42514:itm2bb
gene id: 42514:itm2bb
uniprot id: A0A3B4CQ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

42514:si:dkey-174m14.3
gene id: 42514:si:dkey-174m14.3
uniprot id: A0A3B4BLJ8
names: Subcellular Location Annotation
messages: Membrane

42514:fmnl1a
gene id: 42514:fmnl1a
uniprot id: A0A3B4E3N9
names: Similarity
messages: Belongs to the formin homology family.

42514:fam174b
gene id: 42514:fam174b
uniprot id: A0A3B4CJH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

42514:scgn
gene id: 42514:scgn
uniprot id: A0A3B4DRH2
names: Subcellular Location Annotation
messages: Cytoplasm

42514:nkx3-1
gene id: 42514:nkx3-1
uniprot id: A0A3B4CSK0
names: Subcellular Location Annotation
messages: Nucleus

42514:ankrd34c
gene id: 42514:ankrd34c
uniprot id: A0A3B4DQ78
names: Similarity
messages: Belongs to the ANKRD34 family.

42514:epdl2
gene id: 42514:epdl2
uniprot id: A0A3B4C951
names: Similarity
messages: Belongs to the ependymin family.

42514:gtf2e1
gene id: 42514:gtf2e1
uniprot id: A0A3B4EJT3
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

42514:rpl10
gene id: 42514:rpl10
uniprot id: A0A3B4CB39
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

42514:tor2a
gene id: 42514:tor2a
uniprot id: A0A3B4ERD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

42514:rtbdn
gene id: 42514:rtbdn
uniprot id: A0A3B4CK08
names: Similarity
messages: Belongs to the folate receptor family.

42514:tbx4
gene id: 42514:tbx4
uniprot id: A0A3B4BT26
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:hoxc9a
gene id: 42514:hoxc9a
uniprot id: A0A3B4CUX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.