420245:LBRM 07 0030
gene id: 420245:LBRM_07_0030
uniprot id: A0A3P3YYD1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

420245:LBRM 24 2090
gene id: 420245:LBRM_24_2090
uniprot id: A0A3P3Z8A0
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

420245:LBRM 29 2310
gene id: 420245:LBRM_29_2310
uniprot id: A0A3P3ZC25
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

420245:LBRM 24 2150
gene id: 420245:LBRM_24_2150
uniprot id: A0A3P3Z876
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

420245:LBRM 35 2280
gene id: 420245:LBRM_35_2280
uniprot id: A0A3P3ZIF6
names: Similarity
messages: Belongs to the PPP phosphatase family.

420245:LBRM 17 1580
gene id: 420245:LBRM_17_1580
uniprot id: A0A3P3Z334
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 27 0690
gene id: 420245:LBRM_27_0690
uniprot id: A0A3P3ZA00
names: Similarity
messages: Belongs to the WD repeat SMU1 family.

420245:LBRM 28 0920
gene id: 420245:LBRM_28_0920
uniprot id: A0A3P3ZAP8
names: Similarity
messages: Belongs to the MCM family.

420245:LBRM 30 0760
gene id: 420245:LBRM_30_0760
uniprot id: A0A3P3ZCK4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

420245:LBRM 06 0100
gene id: 420245:LBRM_06_0100
uniprot id: A0A3P3YXY6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

420245:LBRM 01 0060
gene id: 420245:LBRM_01_0060
uniprot id: A0A3P3YWI9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 32 3720
gene id: 420245:LBRM_32_3720
uniprot id: A0A3P3ZF32
names: Similarity
messages: Belongs to the FAM161 family.

420245:LBRM 22 1260
gene id: 420245:LBRM_22_1260
uniprot id: A0A3P3Z6U1
names: Similarity
messages: Belongs to the MAK16 family.

420245:LBRM 35 0160
gene id: 420245:LBRM_35_0160
uniprot id: A0A3P3ZHZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Nucleus

420245:LBRM 19 1470
gene id: 420245:LBRM_19_1470
uniprot id: A0A3P3Z3Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

420245:LBRM 33 0830
gene id: 420245:LBRM_33_0830
uniprot id: A0A3P3Z6P9
names: Similarity
messages: Belongs to the ATPase gamma chain family.

420245:LBRM 28 2230
gene id: 420245:LBRM_28_2230
uniprot id: A0A3P3ZAY4
names: Similarity
messages: Belongs to the DPCD family.

420245:LBRM 31 1760
gene id: 420245:LBRM_31_1760
uniprot id: A0A3P3ZDN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

420245:LBRM 15 1380
gene id: 420245:LBRM_15_1380
uniprot id: A0A3P3Z240
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

420245:LBRM 32 3960
gene id: 420245:LBRM_32_3960
uniprot id: A0A3P3ZF69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

420245:LBRM 32 1310
gene id: 420245:LBRM_32_1310
uniprot id: A0A3P3ZET2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

420245:LBRM 24 0340
gene id: 420245:LBRM_24_0340
uniprot id: A0A3P3Z7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 33 3480
gene id: 420245:LBRM_33_3480
uniprot id: A0A3P3ZGM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

420245:LBRM 23 0040
gene id: 420245:LBRM_23_0040
uniprot id: A0A3P3Z6X4
names: Subcellular Location Annotation
messages: nucleolus

420245:LBRM 28 2700
gene id: 420245:LBRM_28_2700
uniprot id: A0A3P3ZB93
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

420245:LBRM 22 0370
gene id: 420245:LBRM_22_0370
uniprot id: A0A3P3Z6M0
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

420245:LBRM 32 4050
gene id: 420245:LBRM_32_4050
uniprot id: A0A3P3ZFL8
names: Similarity
messages: Belongs to the SHQ1 family.

420245:LBRM 24 0320
gene id: 420245:LBRM_24_0320
uniprot id: A0A3P3Z7Q1
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Homodimer.

420245:LBRM 30 3760
gene id: 420245:LBRM_30_3760
uniprot id: A0A3P3ZDV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: P1 and P2 exist as dimers at the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

420245:LBRM 35 5180
gene id: 420245:LBRM_35_5180
uniprot id: A0A3P3ZJM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

420245:LBRM 28 1220
gene id: 420245:LBRM_28_1220
uniprot id: A0A3P3ZAS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

420245:LBRM 28 2600
gene id: 420245:LBRM_28_2600
uniprot id: A0A3P3ZB79
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.

420245:LBRM 25 0260
gene id: 420245:LBRM_25_0260
uniprot id: A0A3P3Z869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

420245:LBRM 31 2110
gene id: 420245:LBRM_31_2110
uniprot id: A0A3P3ZDU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome.
messages: Cytoplasm
messages: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Part of the 60S ribosomal subunit.

420245:LBRM 33 2900
gene id: 420245:LBRM_33_2900
uniprot id: A0A3P3ZG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 09 0500
gene id: 420245:LBRM_09_0500
uniprot id: A0A3P3YZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

420245:LBRM 30 1670
gene id: 420245:LBRM_30_1670
uniprot id: A0A3P3ZCL8
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 12 0040
gene id: 420245:LBRM_12_0040
uniprot id: A0A3P3Z0E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

420245:LBRM 22 0600
gene id: 420245:LBRM_22_0600
uniprot id: A0A3P3Z6V3
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

420245:LBRM 19 1750
gene id: 420245:LBRM_19_1750
uniprot id: A0A3P3Z496
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

420245:LBRM 31 2290
gene id: 420245:LBRM_31_2290
uniprot id: A0A3P3ZDU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome.
messages: Cytoplasm
messages: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Part of the 60S ribosomal subunit.

420245:LBRM 11 0790
gene id: 420245:LBRM_11_0790
uniprot id: A0A3P3Z082
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

420245:LBRM 34 4670
gene id: 420245:LBRM_34_4670
uniprot id: A0A3P3ZI05
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 03 0100
gene id: 420245:LBRM_03_0100
uniprot id: A0A3P3YWY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

420245:LBRM 23 1490
gene id: 420245:LBRM_23_1490
uniprot id: A0A3P3Z7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 16 1430
gene id: 420245:LBRM_16_1430
uniprot id: A0A3P3Z2H1
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

420245:LBRM 19 0110
gene id: 420245:LBRM_19_0110
uniprot id: A0A3P3Z056
names: Similarity
messages: Belongs to the PPase family.

420245:LBRM 28 1990
gene id: 420245:LBRM_28_1990
uniprot id: A0A3P3ZB17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

420245:LBRM 11 0700
gene id: 420245:LBRM_11_0700
uniprot id: A0A3P3Z096
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

420245:LBRM 19 0520
gene id: 420245:LBRM_19_0520
uniprot id: A0A3P3Z3N9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

420245:LBRM 02 0020
gene id: 420245:LBRM_02_0020
uniprot id: A0A3P3YWP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 13 1530
gene id: 420245:LBRM_13_1530
uniprot id: A0A3P3Z169
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

420245:LBRM 33 0630
gene id: 420245:LBRM_33_0630
uniprot id: A0A3P3ZFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS41 family.
messages: Mitochondrion

420245:LBRM 32 1220
gene id: 420245:LBRM_32_1220
uniprot id: A0A3P3ZEF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 03 0370
gene id: 420245:LBRM_03_0370
uniprot id: A0A3P3YX63
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 11 0290
gene id: 420245:LBRM_11_0290
uniprot id: A0A3P3Z0D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.
messages: Membrane

420245:LBRM 28 1100
gene id: 420245:LBRM_28_1100
uniprot id: A0A3P3ZAU5
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

420245:LBRM 27 0360
gene id: 420245:LBRM_27_0360
uniprot id: A0A3P3ZGJ3
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 23 0370
gene id: 420245:LBRM_23_0370
uniprot id: A0A3P3Z704
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

420245:LBRM 24 1450
gene id: 420245:LBRM_24_1450
uniprot id: A0A3P3Z7T5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 04 0010
gene id: 420245:LBRM_04_0010
uniprot id: A0A3P3YYK2
names: Cofactor
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.

420245:LBRM 05 0410
gene id: 420245:LBRM_05_0410
uniprot id: A0A3P3YXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

420245:LBRM 09 1540
gene id: 420245:LBRM_09_1540
uniprot id: A0A3P3YZF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TET family. JBP1 subfamily.
messages: Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU). DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. Also specifically binds to base J-containing DNA (J-DNA). Involved in propagation and maintenance of DNA base J synthesis initiated by JBP2 by specifically binding already synthesized DNA base J and propagating J synthesis. Thymine dioxygenase activity and J-DNA-binding are independent functions.
messages: Monomer. Binds to DNA as a monomer.
messages: Nucleus

420245:LBRM 10 0410
gene id: 420245:LBRM_10_0410
uniprot id: A0A3P3YZQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

420245:LBRM 35 0680
gene id: 420245:LBRM_35_0680
uniprot id: A0A3P3ZHY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

420245:LBRM 23 1360
gene id: 420245:LBRM_23_1360
uniprot id: A0A3P3Z7A3
names: Similarity
messages: Belongs to the RICTOR family.

420245:LBRM 04 0570
gene id: 420245:LBRM_04_0570
uniprot id: A0A3P3YXD3
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 31 2970
gene id: 420245:LBRM_31_2970
uniprot id: A0A3P3ZDY0
names: Similarity
messages: Belongs to the PPP phosphatase family.

420245:LBRM 35 0150
gene id: 420245:LBRM_35_0150
uniprot id: A0A3P3ZHU3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

420245:LBRM 04 0880
gene id: 420245:LBRM_04_0880
uniprot id: A0A3P3YXG8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

420245:LBRM 29 2320
gene id: 420245:LBRM_29_2320
uniprot id: A0A3P3ZCC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex.
messages: Mitochondrion inner membrane

420245:LBRM 07 0590
gene id: 420245:LBRM_07_0590
uniprot id: A0A3P3YYI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

420245:LBRM 34 4560
gene id: 420245:LBRM_34_4560
uniprot id: A0A3P3ZHJ0
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 35 2060
gene id: 420245:LBRM_35_2060
uniprot id: A0A3P3ZIC4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Nucleus
messages: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport.
messages: The vault ribonucleoprotein particle is a huge (400 A x 670 A) cage structure of 12.9 MDa. It consists of a dimer of half-vaults, with each half-vault comprising 39 identical major vault protein (MVP) chains, PARP4 and one or more vault RNAs (vRNAs).

420245:LBRM 02 0070
gene id: 420245:LBRM_02_0070
uniprot id: A0A3P3YWT4
names: Similarity
messages: Belongs to the cytochrome b5 family.

420245:LBRM 15 0030
gene id: 420245:LBRM_15_0030
uniprot id: A0A3P3Z1N4
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

420245:LBRM 18 0900
gene id: 420245:LBRM_18_0900
uniprot id: A0A3P3Z3B8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

420245:LBRM 21 0390
gene id: 420245:LBRM_21_0390
uniprot id: A0A3P3Z5Y3
names: Similarity
messages: Belongs to the VPS51 family.

420245:LBRM 16 1210
gene id: 420245:LBRM_16_1210
uniprot id: A0A3P3ZC08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

420245:LBRM 28 0570
gene id: 420245:LBRM_28_0570
uniprot id: A0A3P3ZAH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA.
messages: Nucleus

420245:LBRM 10 0380
gene id: 420245:LBRM_10_0380
uniprot id: A0A3P3YZP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

420245:LBRM 34 0150
gene id: 420245:LBRM_34_0150
uniprot id: A0A3P3ZGQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

420245:LBRM 24 0020
gene id: 420245:LBRM_24_0020
uniprot id: A0A3P3Z7F0
names: Subcellular Location Annotation
messages: clathrin-coated pit

420245:LBRM 27 2520
gene id: 420245:LBRM_27_2520
uniprot id: A0A3P3ZA81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

420245:LBRM 28 3110
gene id: 420245:LBRM_28_3110
uniprot id: A0A3P3ZBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

420245:LBRM 22 1420
gene id: 420245:LBRM_22_1420
uniprot id: A0A3P3Z745
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

420245:LBRM 08 0210
gene id: 420245:LBRM_08_0210
uniprot id: A0A3P3YYT3
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

420245:LBRM 14 1650
gene id: 420245:LBRM_14_1650
uniprot id: A0A3P3Z1W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

420245:LBRM 14 0980
gene id: 420245:LBRM_14_0980
uniprot id: A0A3P3Z1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 34 1580
gene id: 420245:LBRM_34_1580
uniprot id: A0A3P3ZGY1
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

420245:LBRM 33 0270
gene id: 420245:LBRM_33_0270
uniprot id: A0A3P3ZFH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

420245:LBRM 35 1950
gene id: 420245:LBRM_35_1950
uniprot id: A0A3P3ZIC3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

420245:LBRM 32 4130
gene id: 420245:LBRM_32_4130
uniprot id: A0A3P3ZFM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

420245:LBRM 25 1240
gene id: 420245:LBRM_25_1240
uniprot id: A0A3P3Z8M1
names: Similarity
messages: Belongs to the cullin family.

420245:LBRM 25 1320
gene id: 420245:LBRM_25_1320
uniprot id: A0A3P3Z8I0
names: Subcellular Location Annotation
messages: cilium axoneme

420245:LBRM 28 2950
gene id: 420245:LBRM_28_2950
uniprot id: A0A3P3ZB69
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

420245:LBRM 13 1420
gene id: 420245:LBRM_13_1420
uniprot id: A0A3P3Z197
names: Similarity
messages: Belongs to the GTR/RAG GTP-binding protein family.

420245:LBRM 06 1150
gene id: 420245:LBRM_06_1150
uniprot id: A0A3P3YYB0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

420245:LBRM 06 1160
gene id: 420245:LBRM_06_1160
uniprot id: A0A3P3YYB2
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 14 0760
gene id: 420245:LBRM_14_0760
uniprot id: A0A3P3Z1N7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL21 family.

420245:LBRM 25 1960
gene id: 420245:LBRM_25_1960
uniprot id: A0A3P3Z8T6
names: Similarity
messages: Belongs to the adenylate kinase family.

420245:LBRM 18 0450
gene id: 420245:LBRM_18_0450
uniprot id: A0A3P3Z386
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

420245:LBRM 29 2840
gene id: 420245:LBRM_29_2840
uniprot id: A0A3P3ZC48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 34 3230
gene id: 420245:LBRM_34_3230
uniprot id: A0A3P3ZH82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum

420245:LBRM 29 0780
gene id: 420245:LBRM_29_0780
uniprot id: A0A3P3ZBI5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

420245:LBRM 34 1980
gene id: 420245:LBRM_34_1980
uniprot id: A0A3P3ZH80
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.

420245:LBRM 04 0310
gene id: 420245:LBRM_04_0310
uniprot id: A0A3P3YXA1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

420245:LBRM 19 1820
gene id: 420245:LBRM_19_1820
uniprot id: A0A3P3Z492
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

420245:LBRM 01 0210
gene id: 420245:LBRM_01_0210
uniprot id: A0A3P3YWG4
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 15 0100
gene id: 420245:LBRM_15_0100
uniprot id: A0A3P3Z1N8
names: Similarity
messages: Belongs to the FMO family.

420245:LBRM 16 0810
gene id: 420245:LBRM_16_0810
uniprot id: A0A3P3Z2C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69.2) family.
messages: Involved in cellular auxin homeostasis by regulating auxin metabolism. Regulates intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signaling.
messages: Membrane

420245:LBRM 33 0710
gene id: 420245:LBRM_33_0710
uniprot id: A0A3P3ZFH3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

420245:LBRM 19 1690
gene id: 420245:LBRM_19_1690
uniprot id: A0A3P3Z400
names: Similarity
messages: Belongs to the peptidase C1 family.

420245:LBRM 35 3170
gene id: 420245:LBRM_35_3170
uniprot id: A0A3P3ZIP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

420245:LBRM 35 6180
gene id: 420245:LBRM_35_6180
uniprot id: A0A3P3ZJJ9
names: Similarity
messages: Belongs to the GTR/RAG GTP-binding protein family.

420245:LBRM 34 2000
gene id: 420245:LBRM_34_2000
uniprot id: A0A3P3ZH21
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 28 0960
gene id: 420245:LBRM_28_0960
uniprot id: A0A3P3ZAX2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

420245:LBRM 25 0120
gene id: 420245:LBRM_25_0120
uniprot id: A0A3P3Z8E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

420245:LBRM 15 0402
gene id: 420245:LBRM_15_0402
uniprot id: A0A3P3Z1R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: P1 and P2 exist as dimers at the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

420245:LBRM 24 0240
gene id: 420245:LBRM_24_0240
uniprot id: A0A3P3Z7H6
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

420245:LBRM 18 0980
gene id: 420245:LBRM_18_0980
uniprot id: A0A3P3Z3C8
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.

420245:LBRM 35 6410
gene id: 420245:LBRM_35_6410
uniprot id: A0A3P3ZJL4
names: Similarity
messages: Belongs to the CNOT10 family.

420245:LBRM 26 2370
gene id: 420245:LBRM_26_2370
uniprot id: A0A3P3Z9U8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

420245:LBRM 26 0880
gene id: 420245:LBRM_26_0880
uniprot id: A0A3P3Z921
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 02 0050
gene id: 420245:LBRM_02_0050
uniprot id: A0A3P3YXZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 14 0640
gene id: 420245:LBRM_14_0640
uniprot id: A0A3P3Z1N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

420245:LBRM 21 0460
gene id: 420245:LBRM_21_0460
uniprot id: A0A3P3Z5Z1
names: Similarity
messages: Belongs to the peptidase C19 family.

420245:LBRM 06 0800
gene id: 420245:LBRM_06_0800
uniprot id: A0A3P3YY70
names: Similarity
messages: Belongs to the lipin family.

420245:LBRM 28 2610
gene id: 420245:LBRM_28_2610
uniprot id: A0A3P3ZB27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

420245:LBRM 24 1700
gene id: 420245:LBRM_24_1700
uniprot id: A0A3P3Z7X0
names: Function
names: Similarity
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

420245:LBRM 34 0060
gene id: 420245:LBRM_34_0060
uniprot id: A0A3P3YYZ8
names: Similarity
messages: Belongs to the pyruvate kinase family.

420245:LBRM 11 0850
gene id: 420245:LBRM_11_0850
uniprot id: A0A3P3Z099
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

420245:LBRM 05 1090
gene id: 420245:LBRM_05_1090
uniprot id: A0A3P3YY55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

420245:LBRM 34 0280
gene id: 420245:LBRM_34_0280
uniprot id: A0A3P3ZGC5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

420245:LBRM 35 4660
gene id: 420245:LBRM_35_4660
uniprot id: A0A3P3ZJL0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

420245:LBRM 34 0690
gene id: 420245:LBRM_34_0690
uniprot id: A0A3P3ZH00
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

420245:LBRM 32 4140
gene id: 420245:LBRM_32_4140
uniprot id: A0A3P3ZH28
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

420245:LBRM 14 0340
gene id: 420245:LBRM_14_0340
uniprot id: A0A3P3Z1A8
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

420245:LBRM 25 1990
gene id: 420245:LBRM_25_1990
uniprot id: A0A3P3Z8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

420245:LBRM 32 0500
gene id: 420245:LBRM_32_0500
uniprot id: A0A3P3Z7M1
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

420245:LBRM 13 0200
gene id: 420245:LBRM_13_0200
uniprot id: A0A3P3Z0R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

420245:LBRM 28 2060
gene id: 420245:LBRM_28_2060
uniprot id: A0A3P3ZB31
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

420245:LBRM 32 0170
gene id: 420245:LBRM_32_0170
uniprot id: A0A3P3ZE45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 10 0270
gene id: 420245:LBRM_10_0270
uniprot id: A0A3P3YZI7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

420245:LBRM 18 0590
gene id: 420245:LBRM_18_0590
uniprot id: A0A3P3Z397
names: Similarity
messages: Belongs to the TBCC family.

420245:LBRM 18 0620
gene id: 420245:LBRM_18_0620
uniprot id: A0A3P3Z387
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

420245:LBRM 31 0400
gene id: 420245:LBRM_31_0400
uniprot id: A0A3P3ZD99
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 34 3970
gene id: 420245:LBRM_34_3970
uniprot id: A0A3P3ZHD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 26 1990
gene id: 420245:LBRM_26_1990
uniprot id: A0A3P3Z9F7
names: Similarity
messages: Belongs to the peptidase C48 family.

420245:LBRM 29 0510
gene id: 420245:LBRM_29_0510
uniprot id: A0A3P3ZBL6
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

420245:LBRM 13 0380
gene id: 420245:LBRM_13_0380
uniprot id: A0A3P3Z0U5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

420245:LBRM 22 1460
gene id: 420245:LBRM_22_1460
uniprot id: A0A3P3Z745
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

420245:LBRM 33 0400
gene id: 420245:LBRM_33_0400
uniprot id: A0A3P3ZFP0
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 30 2200
gene id: 420245:LBRM_30_2200
uniprot id: A0A3P3ZCT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

420245:LBRM 23 1700
gene id: 420245:LBRM_23_1700
uniprot id: A0A3P3Z7C5
names: Similarity
messages: Belongs to the TIP41 family.

420245:LBRM 33 1970
gene id: 420245:LBRM_33_1970
uniprot id: A0A3P3ZFS8
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 32 0980
gene id: 420245:LBRM_32_0980
uniprot id: A0A3P3ZEZ3
names: Similarity
messages: Belongs to the cytidylyltransferase family.

420245:LBRM 27 0270
gene id: 420245:LBRM_27_0270
uniprot id: A0A3P3Z9N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Mitochondrion
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

420245:LBRM 35 2720
gene id: 420245:LBRM_35_2720
uniprot id: A0A3P3ZJ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

420245:LBRM 05 0560
gene id: 420245:LBRM_05_0560
uniprot id: A0A3P3YXQ4
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 33 3510
gene id: 420245:LBRM_33_3510
uniprot id: A0A3P3ZG96
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

420245:LBRM 30 2420
gene id: 420245:LBRM_30_2420
uniprot id: A0A3P3ZCV3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

420245:LBRM 11 0330
gene id: 420245:LBRM_11_0330
uniprot id: A0A3P3Z1D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane

420245:LBRM 19 0590
gene id: 420245:LBRM_19_0590
uniprot id: A0A3P3Z3P4
names: Subcellular Location Annotation
messages: Cell membrane

420245:LBRM 31 3310
gene id: 420245:LBRM_31_3310
uniprot id: A0A3P3ZE05
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

420245:LBRM 33 2820
gene id: 420245:LBRM_33_2820
uniprot id: A0A3P3ZGR1
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

420245:LBRM 14 0610
gene id: 420245:LBRM_14_0610
uniprot id: A0A3P3Z1D6
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 35 1110
gene id: 420245:LBRM_35_1110
uniprot id: A0A3P3ZIA3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

420245:LBRM 23 0980
gene id: 420245:LBRM_23_0980
uniprot id: A0A3P3Z761
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

420245:LBRM 23 0420
gene id: 420245:LBRM_23_0420
uniprot id: A0A3P3Z705
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 09 0220
gene id: 420245:LBRM_09_0220
uniprot id: A0A3P3YZ77
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 30 1980
gene id: 420245:LBRM_30_1980
uniprot id: A0A3P3ZCS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 19 1220
gene id: 420245:LBRM_19_1220
uniprot id: A0A3P3Z448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

420245:LBRM 24 1690
gene id: 420245:LBRM_24_1690
uniprot id: A0A3P3Z888
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

420245:LBRM 29 2820
gene id: 420245:LBRM_29_2820
uniprot id: A0A3P3ZCG8
names: Similarity
messages: Belongs to the IFT56 family.

420245:LBRM 04 1170
gene id: 420245:LBRM_04_1170
uniprot id: A0A3P3YXL9
names: Similarity
messages: Belongs to the FBPase class 1 family.

420245:LBRM 14 1020
gene id: 420245:LBRM_14_1020
uniprot id: A0A3P3Z1K6
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 34 3860
gene id: 420245:LBRM_34_3860
uniprot id: A0A3P3ZHC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

420245:LBRM 23 1890
gene id: 420245:LBRM_23_1890
uniprot id: A0A3P3YXQ6
names: Similarity
messages: Belongs to the COG4 family.

420245:LBRM 22 0390
gene id: 420245:LBRM_22_0390
uniprot id: A0A3P3Z6K0
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 10 0970
gene id: 420245:LBRM_10_0970
uniprot id: A0A3P3YZT5
names: Similarity
messages: Belongs to the histone H3 family.

420245:LBRM 34 3560
gene id: 420245:LBRM_34_3560
uniprot id: A0A3P3ZHA0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

420245:LBRM 02 0580
gene id: 420245:LBRM_02_0580
uniprot id: A0A3P3YWV7
names: Similarity
messages: Belongs to the ARPC4 family.

420245:LBRM 28 1660
gene id: 420245:LBRM_28_1660
uniprot id: A0A3P3ZAZ0
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 06 0620
gene id: 420245:LBRM_06_0620
uniprot id: A0A3P3YY54
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

420245:LBRM 34 1760
gene id: 420245:LBRM_34_1760
uniprot id: A0A3P3ZH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

420245:LBRM 13 1540
gene id: 420245:LBRM_13_1540
uniprot id: A0A3P3Z1D1
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

420245:LBRM 25 1680
gene id: 420245:LBRM_25_1680
uniprot id: A0A3P3Z8P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

420245:LBRM 28 0590
gene id: 420245:LBRM_28_0590
uniprot id: A0A3P3ZAI9
names: Similarity
messages: Belongs to the VPS37 family.

420245:LBRM 28 2890
gene id: 420245:LBRM_28_2890
uniprot id: A0A3P3ZBC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

420245:LBRM 34 1180
gene id: 420245:LBRM_34_1180
uniprot id: A0A3P3ZGP7
names: Similarity
messages: Belongs to the AAA ATPase family.

420245:LBRM 24 2140
gene id: 420245:LBRM_24_2140
uniprot id: A0A3P3Z812
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

420245:LBRM 04 0530
gene id: 420245:LBRM_04_0530
uniprot id: A0A3P3YXE3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

420245:LBRM 31 1950
gene id: 420245:LBRM_31_1950
uniprot id: A0A3P3ZDP7
names: Similarity
messages: Belongs to the cullin family.

420245:LBRM 28 1030
gene id: 420245:LBRM_28_1030
uniprot id: A0A3P3ZD70
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

420245:LBRM 35 4000
gene id: 420245:LBRM_35_4000
uniprot id: A0A3P3ZJF6
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

420245:LBRM 31 3620
gene id: 420245:LBRM_31_3620
uniprot id: A0A3P3ZE32
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 03 0450
gene id: 420245:LBRM_03_0450
uniprot id: A0A3P3YX15
names: Similarity
messages: Belongs to the AAA ATPase family.

420245:LBRM 35 2110
gene id: 420245:LBRM_35_2110
uniprot id: A0A3P3ZID1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: cytoskeleton

420245:LBRM 35 1920
gene id: 420245:LBRM_35_1920
uniprot id: A0A3P3ZIH8
names: Similarity
messages: Belongs to the COG3 family.

420245:LBRM 23 0150
gene id: 420245:LBRM_23_0150
uniprot id: A0A3P3Z775
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Vacuole membrane

420245:LBRM 28 0670
gene id: 420245:LBRM_28_0670
uniprot id: A0A3P3ZAI6
names: Similarity
messages: Belongs to the WD repeat SEC13 family.

420245:LBRM 30 3100
gene id: 420245:LBRM_30_3100
uniprot id: A0A3P3ZD11
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.

420245:LBRM 33 0660
gene id: 420245:LBRM_33_0660
uniprot id: A0A3P3ZFE6
names: Similarity
messages: Belongs to the IFT57 family.

420245:LBRM 19 1300
gene id: 420245:LBRM_19_1300
uniprot id: A0A3P3Z3V3
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

420245:LBRM 18 0290
gene id: 420245:LBRM_18_0290
uniprot id: A0A3P3Z347
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

420245:LBRM 30 1010
gene id: 420245:LBRM_30_1010
uniprot id: A0A3P3ZCF3
names: Function
names: Similarity
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.

420245:LBRM 35 6710
gene id: 420245:LBRM_35_6710
uniprot id: A0A3P3ZJR4
names: Subcellular Location Annotation
messages: cilium axoneme

420245:LBRM 30 2440
gene id: 420245:LBRM_30_2440
uniprot id: A0A3P3ZCY0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

420245:LBRM 04 0490
gene id: 420245:LBRM_04_0490
uniprot id: A0A3P3YXD9
names: Similarity
messages: Belongs to the peptidase C2 family.

420245:LBRM 27 2370
gene id: 420245:LBRM_27_2370
uniprot id: A0A3P3ZAC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 19 0860
gene id: 420245:LBRM_19_0860
uniprot id: A0A3P3Z3R8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

420245:LBRM 34 1330
gene id: 420245:LBRM_34_1330
uniprot id: A0A3P3ZH60
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

420245:LBRM 24 0160
gene id: 420245:LBRM_24_0160
uniprot id: A0A3P3Z7G0
names: Similarity
messages: Belongs to the phosducin family.

420245:LBRM 09 1350
gene id: 420245:LBRM_09_1350
uniprot id: A0A3P3YZE5
names: Similarity
messages: Belongs to the DeSI family.

420245:LBRM 27 1390
gene id: 420245:LBRM_27_1390
uniprot id: A0A3P3ZA92
names: Similarity
messages: Belongs to the peptidase C19 family.

420245:LBRM 25 1150
gene id: 420245:LBRM_25_1150
uniprot id: A0A3P3Z8M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

420245:LBRM 22 1240
gene id: 420245:LBRM_22_1240
uniprot id: A0A3P3Z6W2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

420245:LBRM 27 1310
gene id: 420245:LBRM_27_1310
uniprot id: A0A3P3Z9Y6
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

420245:LBRM 22 1230
gene id: 420245:LBRM_22_1230
uniprot id: A0A3P3Z6T2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

420245:LBRM 21 2010
gene id: 420245:LBRM_21_2010
uniprot id: A0A3P3Z6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.

420245:LBRM 01 0500
gene id: 420245:LBRM_01_0500
uniprot id: A0A3P3YWJ6
names: Similarity
messages: Belongs to the isochorismatase family.

420245:LBRM 10 1090
gene id: 420245:LBRM_10_1090
uniprot id: A0A3P3YZT5
names: Similarity
messages: Belongs to the histone H3 family.

420245:LBRM 07 0020
gene id: 420245:LBRM_07_0020
uniprot id: A0A3P3YYC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

420245:LBRM 35 6810
gene id: 420245:LBRM_35_6810
uniprot id: A0A3P3ZJS3
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

420245:LBRM 34 3290
gene id: 420245:LBRM_34_3290
uniprot id: A0A3P3ZHK7
names: Function
names: Subcellular Location Annotation
messages: Displays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities. Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation. At the mRNAs 5' end, methylates the ribose 2' OH group of the first transcribed nucleotide, thereby producing a 2'-O-methylpurine cap. At the 3' end, functions as a processivity factor which stimulates the activity of the viral poly(A) polymerase OPG063 that creates mRNA's poly(A) tail. In the presence of OPG102, OPG063 does not dissociate from the RNA allowing tail elongation to around 250 adenylates.
messages: Virion

420245:LBRM 16 0170
gene id: 420245:LBRM_16_0170
uniprot id: A0A3P3Z234
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

420245:LBRM 35 5370
gene id: 420245:LBRM_35_5370
uniprot id: A0A3P3ZJS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

420245:LBRM 34 2340
gene id: 420245:LBRM_34_2340
uniprot id: A0A3P3ZGW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus

420245:LBRM 27 2320
gene id: 420245:LBRM_27_2320
uniprot id: A0A3P3ZAA3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.

420245:LBRM 31 3150
gene id: 420245:LBRM_31_3150
uniprot id: A0A3P3ZDZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

420245:LBRM 18 0130
gene id: 420245:LBRM_18_0130
uniprot id: A0A3P3Z345
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO4 family.
messages: Membrane

420245:LBRM 35 0840
gene id: 420245:LBRM_35_0840
uniprot id: A0A3P3ZI01
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

420245:LBRM 29 1300
gene id: 420245:LBRM_29_1300
uniprot id: A0A3P3ZBS2
names: Similarity
messages: Belongs to the CWC16 family.

420245:LBRM 32 3600
gene id: 420245:LBRM_32_3600
uniprot id: A0A3P3ZFF9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

420245:LBRM 31 1890
gene id: 420245:LBRM_31_1890
uniprot id: A0A3P3ZDU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS3/PSF3 family.
messages: Nucleus

420245:LBRM 28 2400
gene id: 420245:LBRM_28_2400
uniprot id: A0A3P3ZB19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

420245:LBRM 02 0640
gene id: 420245:LBRM_02_0640
uniprot id: A0A3P3YWY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

420245:LBRM 01 0740
gene id: 420245:LBRM_01_0740
uniprot id: A0A3P3YWM9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G.

420245:LBRM 26 2500
gene id: 420245:LBRM_26_2500
uniprot id: A0A3P3Z9P1
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 28 0660
gene id: 420245:LBRM_28_0660
uniprot id: A0A3P3ZAT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

420245:LBRM 31 3590
gene id: 420245:LBRM_31_3590
uniprot id: A0A3P3ZE28
names: Similarity
messages: Belongs to the GAMAD family.

420245:LBRM 28 1060
gene id: 420245:LBRM_28_1060
uniprot id: A0A3P3ZAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

420245:LBRM 24 0920
gene id: 420245:LBRM_24_0920
uniprot id: A0A3P3Z7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

420245:LBRM 33 0280
gene id: 420245:LBRM_33_0280
uniprot id: A0A3P3ZFB2
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 25 1100
gene id: 420245:LBRM_25_1100
uniprot id: A0A3P3Z8U3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

420245:LBRM 32 1270
gene id: 420245:LBRM_32_1270
uniprot id: A0A3P3Z661
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 23 0700
gene id: 420245:LBRM_23_0700
uniprot id: A0A3P3Z7D3
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

420245:LBRM 35 7010
gene id: 420245:LBRM_35_7010
uniprot id: A0A3P3ZJU0
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

420245:LBRM 28 2661
gene id: 420245:LBRM_28_2661
uniprot id: A0A3P3ZBF2
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

420245:LBRM 33 0840
gene id: 420245:LBRM_33_0840
uniprot id: A0A3P3Z6G5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

420245:LBRM 35 7160
gene id: 420245:LBRM_35_7160
uniprot id: A0A3P3ZK13
names: Similarity
messages: Belongs to the UFL1 family.

420245:LBRM 27 2720
gene id: 420245:LBRM_27_2720
uniprot id: A0A3P3ZAA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

420245:LBRM 10 1320
gene id: 420245:LBRM_10_1320
uniprot id: A0A3P3YZX4
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 35 2410
gene id: 420245:LBRM_35_2410
uniprot id: A0A3P3ZIG2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 32 0490
gene id: 420245:LBRM_32_0490
uniprot id: A0A3P3ZEM0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 18 0360
gene id: 420245:LBRM_18_0360
uniprot id: A0A3P3Z368
names: Similarity
messages: Belongs to the FAM221 family.

420245:LBRM 28 2080
gene id: 420245:LBRM_28_2080
uniprot id: A0A3P3ZAX0
names: Similarity
messages: Belongs to the BCP1 family.

420245:LBRM 28 1410
gene id: 420245:LBRM_28_1410
uniprot id: A0A3P3ZAR2
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

420245:LBRM 22 1170
gene id: 420245:LBRM_22_1170
uniprot id: A0A3P3Z6V1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

420245:LBRM 18 1190
gene id: 420245:LBRM_18_1190
uniprot id: A0A3P3Z3F0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

420245:LBRM 30 1970
gene id: 420245:LBRM_30_1970
uniprot id: A0A3P3ZCR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

420245:LBRM 07 1200
gene id: 420245:LBRM_07_1200
uniprot id: A0A3P3YYN1
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

420245:LBRM 17 1500
gene id: 420245:LBRM_17_1500
uniprot id: A0A3P3Z3A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

420245:LBRM 35 7320
gene id: 420245:LBRM_35_7320
uniprot id: A0A3P3ZK91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

420245:LBRM 23 1560
gene id: 420245:LBRM_23_1560
uniprot id: A0A3P3Z7B8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

420245:LBRM 26 0160
gene id: 420245:LBRM_26_0160
uniprot id: A0A3P3Z912
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

420245:LBRM 34 3740
gene id: 420245:LBRM_34_3740
uniprot id: A0A3P3ZHA6
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

420245:LBRM 30 3120
gene id: 420245:LBRM_30_3120
uniprot id: A0A3P3ZD89
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

420245:LBRM 21 2000
gene id: 420245:LBRM_21_2000
uniprot id: A0A3P3Z6E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

420245:LBRM 33 0750
gene id: 420245:LBRM_33_0750
uniprot id: A0A3P3ZFM5
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

420245:LBRM 23 0520
gene id: 420245:LBRM_23_0520
uniprot id: A0A3P3Z779
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

420245:LBRM 32 3560
gene id: 420245:LBRM_32_3560
uniprot id: A0A3P3ZF06
names: Function
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

420245:LBRM 16 1590
gene id: 420245:LBRM_16_1590
uniprot id: A0A3P3Z2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

420245:LBRM 30 0620
gene id: 420245:LBRM_30_0620
uniprot id: A0A3P3ZCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

420245:LBRM 23 1750
gene id: 420245:LBRM_23_1750
uniprot id: A0A3P3Z7C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

420245:LBRM 28 1900
gene id: 420245:LBRM_28_1900
uniprot id: A0A3P3ZAW4
names: Similarity
messages: Belongs to the proteasome subunit S1 family.

420245:LBRM 19 1020
gene id: 420245:LBRM_19_1020
uniprot id: A0A3P3Z3T2
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

420245:LBRM 34 1230
gene id: 420245:LBRM_34_1230
uniprot id: A0A3P3ZH18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 11 0040
gene id: 420245:LBRM_11_0040
uniprot id: A0A3P3Z072
names: Similarity
messages: Belongs to the 14-3-3 family.

420245:LBRM 30 0710
gene id: 420245:LBRM_30_0710
uniprot id: A0A3P3ZCC7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

420245:LBRM 30 2790
gene id: 420245:LBRM_30_2790
uniprot id: A0A3P3ZCY4
names: Function
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

420245:LBRM 27 0220
gene id: 420245:LBRM_27_0220
uniprot id: A0A3P3Z9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

420245:LBRM 32 2050
gene id: 420245:LBRM_32_2050
uniprot id: A0A3P3ZF94
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 11 0950
gene id: 420245:LBRM_11_0950
uniprot id: A0A3P3Z0B3
names: Similarity
messages: Belongs to the SKP1 family.

420245:LBRM 21 1130
gene id: 420245:LBRM_21_1130
uniprot id: A0A3P3Z6E5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

420245:LBRM 04 0960
gene id: 420245:LBRM_04_0960
uniprot id: A0A3P3YXJ3
names: Similarity
messages: Belongs to the adenylate kinase family.

420245:LBRM 08 0540
gene id: 420245:LBRM_08_0540
uniprot id: A0A3P3YYV0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

420245:LBRM 32 0100
gene id: 420245:LBRM_32_0100
uniprot id: A0A3P3ZE43
names: Similarity
messages: Belongs to the WD repeat SEC13 family.

420245:LBRM 30 1240
gene id: 420245:LBRM_30_1240
uniprot id: A0A3P3ZCI5
names: Similarity
messages: Belongs to the importin alpha family.

420245:LBRM 23 1390
gene id: 420245:LBRM_23_1390
uniprot id: A0A3P3Z7K2
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 21 1100
gene id: 420245:LBRM_21_1100
uniprot id: A0A3P3Z6C3
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 18 1640
gene id: 420245:LBRM_18_1640
uniprot id: A0A3P3Z3J3
names: Similarity
messages: Belongs to the NOC2 family.

420245:LBRM 29 2480
gene id: 420245:LBRM_29_2480
uniprot id: A0A3P3ZC30
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by AMP.
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Glycosome
messages: Homotetramer.

420245:LBRM 23 1280
gene id: 420245:LBRM_23_1280
uniprot id: A0A3P3Z792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

420245:LBRM 34 0840
gene id: 420245:LBRM_34_0840
uniprot id: A0A3P3ZGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPC1 family.
messages: Membrane

420245:LBRM 05 0070
gene id: 420245:LBRM_05_0070
uniprot id: A0A3P3YXK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

420245:LBRM 10 0740
gene id: 420245:LBRM_10_0740
uniprot id: A0A3P3YZQ5
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

420245:LBRM 33 0890
gene id: 420245:LBRM_33_0890
uniprot id: A0A3P3Z6N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.

420245:LBRM 35 1290
gene id: 420245:LBRM_35_1290
uniprot id: A0A3P3ZI51
names: Similarity
messages: Belongs to the MEMO1 family.

420245:LBRM 25 0610
gene id: 420245:LBRM_25_0610
uniprot id: A0A3P3Z8A2
names: Function
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

420245:LBRM 07 0900
gene id: 420245:LBRM_07_0900
uniprot id: A0A3P3YYN7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

420245:LBRM 10 0640
gene id: 420245:LBRM_10_0640
uniprot id: A0A3P3YZP5
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

420245:LBRM 29 1810
gene id: 420245:LBRM_29_1810
uniprot id: A0A3P3ZBU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 14 1240
gene id: 420245:LBRM_14_1240
uniprot id: A0A3P3Z4J0
names: Similarity
messages: Belongs to the SNF8 family.

420245:LBRM 26 0110
gene id: 420245:LBRM_26_0110
uniprot id: A0A3P3Z8U8
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 28 1300
gene id: 420245:LBRM_28_1300
uniprot id: A0A3P3ZAP6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

420245:LBRM 35 0920
gene id: 420245:LBRM_35_0920
uniprot id: A0A3P3ZI16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

420245:LBRM 31 2810
gene id: 420245:LBRM_31_2810
uniprot id: A0A3P3ZDV9
names: Similarity
messages: Belongs to the uridine kinase family.

420245:LBRM 28 2260
gene id: 420245:LBRM_28_2260
uniprot id: A0A3P3ZAY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

420245:LBRM 22 1490
gene id: 420245:LBRM_22_1490
uniprot id: A0A3P3Z6W0
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 32 0970
gene id: 420245:LBRM_32_0970
uniprot id: A0A3P3ZGD7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

420245:LBRM 27 0310
gene id: 420245:LBRM_27_0310
uniprot id: A0A3P3Z9U0
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.

420245:LBRM 33 0911
gene id: 420245:LBRM_33_0911
uniprot id: A0A3P3Z6G7
names: Similarity
messages: Belongs to the BolA/IbaG family.

420245:LBRM 19 1080
gene id: 420245:LBRM_19_1080
uniprot id: A0A3P3Z3U1
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 08 0900
gene id: 420245:LBRM_08_0900
uniprot id: A0A3P3YZ01
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

420245:LBRM 22 0300
gene id: 420245:LBRM_22_0300
uniprot id: A0A3P3Z6R7
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

420245:LBRM 35 6680
gene id: 420245:LBRM_35_6680
uniprot id: A0A3P3ZK29
names: Similarity
messages: Belongs to the CAF1 family.

420245:LBRM 34 4130
gene id: 420245:LBRM_34_4130
uniprot id: A0A3P3ZHY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

420245:LBRM 15 0740
gene id: 420245:LBRM_15_0740
uniprot id: A0A3P3Z1X5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Peroxisome membrane

420245:LBRM 14 0230
gene id: 420245:LBRM_14_0230
uniprot id: A0A3P3Z1B0
names: Similarity
messages: Belongs to the SEC5 family.

420245:LBRM 34 0480
gene id: 420245:LBRM_34_0480
uniprot id: A0A3P3ZGE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAP2/GCS1 family.
messages: Cell membrane
messages: Membrane

420245:LBRM 31 2560
gene id: 420245:LBRM_31_2560
uniprot id: A0A3P3ZE24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

420245:LBRM 34 2160
gene id: 420245:LBRM_34_2160
uniprot id: A0A3P3ZHE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KMP-11 family.
messages: Monomer.
messages: cytoskeleton

420245:LBRM 35 3800
gene id: 420245:LBRM_35_3800
uniprot id: A0A3P3ZJB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 14 1350
gene id: 420245:LBRM_14_1350
uniprot id: A0A3P3Z1I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

420245:LBRM 35 1570
gene id: 420245:LBRM_35_1570
uniprot id: A0A3P3ZI82
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

420245:LBRM 28 1910
gene id: 420245:LBRM_28_1910
uniprot id: A0A3P3ZAW5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

420245:LBRM 13 0160
gene id: 420245:LBRM_13_0160
uniprot id: A0A3P3Z0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

420245:LBRM 26 1710
gene id: 420245:LBRM_26_1710
uniprot id: A0A3P3Z9J7
names: Similarity
messages: Belongs to the EAF6 family.

420245:LBRM 23 0650
gene id: 420245:LBRM_23_0650
uniprot id: A0A3P3Z790
names: Similarity
messages: Belongs to the CAF1 family.

420245:LBRM 14 0690
gene id: 420245:LBRM_14_0690
uniprot id: A0A3P3Z1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

420245:LBRM 23 0080
gene id: 420245:LBRM_23_0080
uniprot id: A0A3P3Z6Z9
names: Similarity
messages: Belongs to the arginase family.

420245:LBRM 32 0960
gene id: 420245:LBRM_32_0960
uniprot id: A0A3P3ZEF7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

420245:LBRM 06 0150
gene id: 420245:LBRM_06_0150
uniprot id: A0A3P3YXZ8
names: Similarity
messages: Belongs to the TRM112 family.

420245:LBRM 14 0660
gene id: 420245:LBRM_14_0660
uniprot id: A0A3P3Z1J3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

420245:LBRM 33 1220
gene id: 420245:LBRM_33_1220
uniprot id: A0A3P3ZFK2
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

420245:LBRM 14 0070
gene id: 420245:LBRM_14_0070
uniprot id: A0A3P3Z175
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

420245:LBRM 33 0920
gene id: 420245:LBRM_33_0920
uniprot id: A0A3P3ZG23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

420245:LBRM 35 5860
gene id: 420245:LBRM_35_5860
uniprot id: A0A3P3ZJY6
names: Similarity
messages: Belongs to the CAP family.

420245:LBRM 25 0900
gene id: 420245:LBRM_25_0900
uniprot id: A0A3P3Z8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 33 0860
gene id: 420245:LBRM_33_0860
uniprot id: A0A3P3Z6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Vacuole membrane

420245:LBRM 35 4880
gene id: 420245:LBRM_35_4880
uniprot id: A0A3P3ZJP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

420245:LBRM 30 3380
gene id: 420245:LBRM_30_3380
uniprot id: A0A3P3Z6G4
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

420245:LBRM 23 0060
gene id: 420245:LBRM_23_0060
uniprot id: A0A3P3Z762
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

420245:LBRM 17 0810
gene id: 420245:LBRM_17_0810
uniprot id: A0A3P3Z2W5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 21 1410
gene id: 420245:LBRM_21_1410
uniprot id: A0A3P3Z693
names: Similarity
messages: Belongs to the thymidine kinase family.

420245:LBRM 34 3730
gene id: 420245:LBRM_34_3730
uniprot id: A0A3P3ZHP2
names: Similarity
messages: Belongs to the cullin family.

420245:LBRM 26 1720
gene id: 420245:LBRM_26_1720
uniprot id: A0A3P3Z9H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEATR1/UTP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

420245:LBRM 12 0080
gene id: 420245:LBRM_12_0080
uniprot id: A0A3P3Z0F0
names: Similarity
messages: Belongs to the isochorismatase family.

420245:LBRM 35 1750
gene id: 420245:LBRM_35_1750
uniprot id: A0A3P3ZI93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.

420245:LBRM 32 0240
gene id: 420245:LBRM_32_0240
uniprot id: A0A3P3ZE57
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

420245:LBRM 32 0470
gene id: 420245:LBRM_32_0470
uniprot id: A0A3P3ZE73
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G.

420245:LBRM 15 0990
gene id: 420245:LBRM_15_0990
uniprot id: A0A3P3Z202
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

420245:LBRM 32 0800
gene id: 420245:LBRM_32_0800
uniprot id: A0A3P3ZEK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

420245:LBRM 26 0480
gene id: 420245:LBRM_26_0480
uniprot id: A0A3P3Z958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

420245:LBRM 27 0700
gene id: 420245:LBRM_27_0700
uniprot id: A0A3P3Z9W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF3 family.
messages: Cytoplasm

420245:LBRM 34 5030
gene id: 420245:LBRM_34_5030
uniprot id: A0A3P3ZHM9
names: Similarity
messages: Belongs to the PPR family. P subfamily.

420245:LBRM 16 0060
gene id: 420245:LBRM_16_0060
uniprot id: A0A3P3Z226
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

420245:LBRM 25 1760
gene id: 420245:LBRM_25_1760
uniprot id: A0A3P3Z8R3
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

420245:LBRM 21 0030
gene id: 420245:LBRM_21_0030
uniprot id: A0A3P3Z5U8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

420245:LBRM 28 2830
gene id: 420245:LBRM_28_2830
uniprot id: A0A3P3ZBB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

420245:LBRM 18 1050
gene id: 420245:LBRM_18_1050
uniprot id: A0A3P3Z3K2
names: Similarity
messages: Belongs to the UDPGP type 1 family.

420245:LBRM 35 7240
gene id: 420245:LBRM_35_7240
uniprot id: A0A3P3ZJU7
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 05 0030
gene id: 420245:LBRM_05_0030
uniprot id: A0A3P3YXS9
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

420245:LBRM 33 0520
gene id: 420245:LBRM_33_0520
uniprot id: A0A3P3ZFE9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

420245:LBRM 07 0060
gene id: 420245:LBRM_07_0060
uniprot id: A0A3P3YYE1
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

420245:LBRM 32 0260
gene id: 420245:LBRM_32_0260
uniprot id: A0A3P3ZE88
names: Similarity
messages: Belongs to the heat shock protein 70 family.

420245:LBRM 10 0280
gene id: 420245:LBRM_10_0280
uniprot id: A0A3P3YZP1
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 33 2630
gene id: 420245:LBRM_33_2630
uniprot id: A0A3P3ZGP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

420245:LBRM 09 0210
gene id: 420245:LBRM_09_0210
uniprot id: A0A3P3YZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP96 family.
messages: centrosome

420245:LBRM 26 1260
gene id: 420245:LBRM_26_1260
uniprot id: A0A3P3Z9G0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

420245:LBRM 29 0450
gene id: 420245:LBRM_29_0450
uniprot id: A0A3P3ZBG6
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

420245:LBRM 19 1050
gene id: 420245:LBRM_19_1050
uniprot id: A0A3P3Z3R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

420245:LBRM 22 0400
gene id: 420245:LBRM_22_0400
uniprot id: A0A3P3Z6T4
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

420245:LBRM 35 1230
gene id: 420245:LBRM_35_1230
uniprot id: A0A3P3ZIB2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

420245:LBRM 33 0930
gene id: 420245:LBRM_33_0930
uniprot id: A0A3P3Z6R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

420245:LBRM 34 1920
gene id: 420245:LBRM_34_1920
uniprot id: A0A3P3ZGT3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

420245:LBRM 06 0230
gene id: 420245:LBRM_06_0230
uniprot id: A0A3P3YY20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

420245:LBRM 35 4040
gene id: 420245:LBRM_35_4040
uniprot id: A0A3P3ZJC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

420245:LBRM 35 3980
gene id: 420245:LBRM_35_3980
uniprot id: A0A3P3ZIY5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

420245:LBRM 35 3380
gene id: 420245:LBRM_35_3380
uniprot id: A0A3P3ZJ92
names: Similarity
messages: Belongs to the TBCC family.

420245:LBRM 22 0850
gene id: 420245:LBRM_22_0850
uniprot id: A0A3P3Z6P5
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 30 1170
gene id: 420245:LBRM_30_1170
uniprot id: A0A3P3ZCG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 16 0630
gene id: 420245:LBRM_16_0630
uniprot id: A0A3P3Z278
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

420245:LBRM 10 1120
gene id: 420245:LBRM_10_1120
uniprot id: A0A3P3YZV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 34 3760
gene id: 420245:LBRM_34_3760
uniprot id: A0A3P3ZHA6
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

420245:LBRM 22 1330
gene id: 420245:LBRM_22_1330
uniprot id: A0A3P3Z6U5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

420245:LBRM 06 0390
gene id: 420245:LBRM_06_0390
uniprot id: A0A3P3YY18
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

420245:LBRM 26 0500
gene id: 420245:LBRM_26_0500
uniprot id: A0A3P3Z938
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

420245:LBRM 28 2290
gene id: 420245:LBRM_28_2290
uniprot id: A0A3P3ZB09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

420245:LBRM 08 0600
gene id: 420245:LBRM_08_0600
uniprot id: A0A3P3YYY0
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

420245:LBRM 34 3840
gene id: 420245:LBRM_34_3840
uniprot id: A0A3P3ZHB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

420245:LBRM 29 0730
gene id: 420245:LBRM_29_0730
uniprot id: A0A3P3ZBI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

420245:LBRM 09 0230
gene id: 420245:LBRM_09_0230
uniprot id: A0A3P3YZ25
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

420245:LBRM 35 5790
gene id: 420245:LBRM_35_5790
uniprot id: A0A3P3ZJN1
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 32 2550
gene id: 420245:LBRM_32_2550
uniprot id: A0A3P3ZF49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

420245:LBRM 17 1350
gene id: 420245:LBRM_17_1350
uniprot id: A0A3P3Z2Z9
names: Similarity
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.

420245:LBRM 19 0470
gene id: 420245:LBRM_19_0470
uniprot id: A0A3P3Z3V1
names: Similarity
messages: Belongs to the peptidase M24 family.

420245:LBRM 18 1350
gene id: 420245:LBRM_18_1350
uniprot id: A0A3P3Z3G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 23 1310
gene id: 420245:LBRM_23_1310
uniprot id: A0A3P3Z794
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

420245:LBRM 25 0890
gene id: 420245:LBRM_25_0890
uniprot id: A0A3P3Z8K7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

420245:LBRM 21 2030
gene id: 420245:LBRM_21_2030
uniprot id: A0A3P3Z6F3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

420245:LBRM 23 0270
gene id: 420245:LBRM_23_0270
uniprot id: A0A3P3Z782
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

420245:LBRM 28 0710
gene id: 420245:LBRM_28_0710
uniprot id: A0A3P3ZAP7
names: Similarity
messages: Belongs to the PPP phosphatase family.

420245:LBRM 35 4140
gene id: 420245:LBRM_35_4140
uniprot id: A0A3P3ZIZ8
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

420245:LBRM 03 0640
gene id: 420245:LBRM_03_0640
uniprot id: A0A3P3YX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

420245:LBRM 03 0210
gene id: 420245:LBRM_03_0210
uniprot id: A0A3P3YWZ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

420245:LBRM 34 3190
gene id: 420245:LBRM_34_3190
uniprot id: A0A3P3ZHD6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

420245:LBRM 31 0570
gene id: 420245:LBRM_31_0570
uniprot id: A0A3P3YWP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Membrane

420245:LBRM 33 2040
gene id: 420245:LBRM_33_2040
uniprot id: A0A3P3ZFT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus

420245:LBRM 35 2150
gene id: 420245:LBRM_35_2150
uniprot id: A0A3P3ZID5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

420245:LBRM 08 0330
gene id: 420245:LBRM_08_0330
uniprot id: A0A3P3YYR9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

420245:LBRM 28 1640
gene id: 420245:LBRM_28_1640
uniprot id: A0A3P3ZB21
names: Similarity
messages: Belongs to the syntaxin family.

420245:LBRM 19 0950
gene id: 420245:LBRM_19_0950
uniprot id: A0A3P3Z3S5
names: Similarity
messages: Belongs to the histone H3 family.

420245:LBRM 34 2300
gene id: 420245:LBRM_34_2300
uniprot id: A0A3P3ZH50
names: Similarity
messages: Belongs to the peptidase M24B family.

420245:LBRM 34 3310
gene id: 420245:LBRM_34_3310
uniprot id: A0A3P3ZHE6
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

420245:LBRM 30 0280
gene id: 420245:LBRM_30_0280
uniprot id: A0A3P3ZCM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

420245:LBRM 33 0210
gene id: 420245:LBRM_33_0210
uniprot id: A0A3P3ZFZ6
names: Similarity
messages: Belongs to the peptidase M14 family.

420245:LBRM 19 1860
gene id: 420245:LBRM_19_1860
uniprot id: A0A3P3Z4A3
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 35 3230
gene id: 420245:LBRM_35_3230
uniprot id: A0A3P3ZJ28
names: Similarity
messages: Belongs to the glutathione peroxidase family.

420245:LBRM 21 2070
gene id: 420245:LBRM_21_2070
uniprot id: A0A3P3Z6G0
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

420245:LBRM 05 1160
gene id: 420245:LBRM_05_1160
uniprot id: A0A3P3YXZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

420245:LBRM 14 0380
gene id: 420245:LBRM_14_0380
uniprot id: A0A3P3Z1H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

420245:LBRM 30 0560
gene id: 420245:LBRM_30_0560
uniprot id: A0A3P3ZCI6
names: Similarity
messages: Belongs to the bystin family.

420245:LBRM 27 2430
gene id: 420245:LBRM_27_2430
uniprot id: A0A3P3ZAJ8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

420245:LBRM 27 1690
gene id: 420245:LBRM_27_1690
uniprot id: A0A3P3ZA53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

420245:LBRM 03 0400
gene id: 420245:LBRM_03_0400
uniprot id: A0A3P3YX05
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

420245:LBRM 26 1630
gene id: 420245:LBRM_26_1630
uniprot id: A0A3P3Z9J4
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

420245:LBRM 30 0540
gene id: 420245:LBRM_30_0540
uniprot id: A0A3P3ZCC4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

420245:LBRM 34 3200
gene id: 420245:LBRM_34_3200
uniprot id: A0A3P3ZHD6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

420245:LBRM 30 3470
gene id: 420245:LBRM_30_3470
uniprot id: A0A3P3ZD36
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

420245:LBRM 35 6030
gene id: 420245:LBRM_35_6030
uniprot id: A0A3P3ZJI7
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

420245:LBRM 29 0040
gene id: 420245:LBRM_29_0040
uniprot id: A0A3P3ZBC0
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

420245:LBRM 35 4090
gene id: 420245:LBRM_35_4090
uniprot id: A0A3P3ZJE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAP2/GCS1 family.
messages: Cell membrane
messages: Membrane

420245:LBRM 30 0480
gene id: 420245:LBRM_30_0480
uniprot id: A0A3P3ZC99
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 09 0900
gene id: 420245:LBRM_09_0900
uniprot id: A0A3P3YZ94
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

420245:LBRM 31 3330
gene id: 420245:LBRM_31_3330
uniprot id: A0A3P3ZE17
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 32 2670
gene id: 420245:LBRM_32_2670
uniprot id: A0A3P3ZES0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 35 4440
gene id: 420245:LBRM_35_4440
uniprot id: A0A3P3ZJG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS2/PSF2 family.
messages: Nucleus

420245:LBRM 21 0300
gene id: 420245:LBRM_21_0300
uniprot id: A0A3P3Z5X1
names: Similarity
messages: Belongs to the actin family.

420245:LBRM 29 0610
gene id: 420245:LBRM_29_0610
uniprot id: A0A3P3ZBK6
names: Similarity
messages: Belongs to the NFX1 family.

420245:LBRM 33 2420
gene id: 420245:LBRM_33_2420
uniprot id: A0A3P3ZGM1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 24 2360
gene id: 420245:LBRM_24_2360
uniprot id: A0A3P3Z836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

420245:LBRM 24 2160
gene id: 420245:LBRM_24_2160
uniprot id: A0A3P3Z876
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

420245:LBRM 35 7200
gene id: 420245:LBRM_35_7200
uniprot id: A0A3P3ZJT8
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 28 2250
gene id: 420245:LBRM_28_2250
uniprot id: A0A3P3ZAY8
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

420245:LBRM 08 0920
gene id: 420245:LBRM_08_0920
uniprot id: A0A3P3YYZ7
names: Similarity
messages: Belongs to the SEC3 family.

420245:LBRM 13 0020
gene id: 420245:LBRM_13_0020
uniprot id: A0A3P3Z0U7
names: Similarity
messages: Belongs to the UPP synthase family.

420245:LBRM 19 1850
gene id: 420245:LBRM_19_1850
uniprot id: A0A3P3Z405
names: Similarity
messages: Belongs to the AAA ATPase family.

420245:LBRM 23 0750
gene id: 420245:LBRM_23_0750
uniprot id: A0A3P3Z735
names: Similarity
messages: Belongs to the DIM1 family.

420245:LBRM 35 1480
gene id: 420245:LBRM_35_1480
uniprot id: A0A3P3ZI59
names: Similarity
messages: Belongs to the adenylate kinase family.

420245:LBRM 32 3110
gene id: 420245:LBRM_32_3110
uniprot id: A0A3P3ZF04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

420245:LBRM 28 2960
gene id: 420245:LBRM_28_2960
uniprot id: A0A3P3ZB67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

420245:LBRM 11 0560
gene id: 420245:LBRM_11_0560
uniprot id: A0A3P3Z0H3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS21 family.

420245:LBRM 29 0850
gene id: 420245:LBRM_29_0850
uniprot id: A0A3P3ZBL3
names: Similarity
messages: Belongs to the peptidase C1 family.

420245:LBRM 10 1260
gene id: 420245:LBRM_10_1260
uniprot id: A0A3P3Z074
names: Similarity
messages: Belongs to the CFAP45 family.

420245:LBRM 33 2090
gene id: 420245:LBRM_33_2090
uniprot id: A0A3P3ZFT4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

420245:LBRM 34 4010
gene id: 420245:LBRM_34_4010
uniprot id: A0A3P3ZHW6
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

420245:LBRM 03 0830
gene id: 420245:LBRM_03_0830
uniprot id: A0A3P3YX56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

420245:LBRM 11 0890
gene id: 420245:LBRM_11_0890
uniprot id: A0A3P3Z0J8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

420245:LBRM 35 4230
gene id: 420245:LBRM_35_4230
uniprot id: A0A3P3ZJE3
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

420245:LBRM 24 1320
gene id: 420245:LBRM_24_1320
uniprot id: A0A3P3Z7W0
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

420245:LBRM 16 0890
gene id: 420245:LBRM_16_0890
uniprot id: A0A3P3Z2C0
names: Similarity
messages: Belongs to the RRP1 family.

420245:LBRM 23 1300
gene id: 420245:LBRM_23_1300
uniprot id: A0A3P3Z7G1
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

420245:LBRM 26 1400
gene id: 420245:LBRM_26_1400
uniprot id: A0A3P3Z974
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

420245:LBRM 27 0320
gene id: 420245:LBRM_27_0320
uniprot id: A0A3P3Z9S8
names: Similarity
messages: Belongs to the CAND family.

420245:LBRM 18 0670
gene id: 420245:LBRM_18_0670
uniprot id: A0A3P3Z3F9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

420245:LBRM 16 0750
gene id: 420245:LBRM_16_0750
uniprot id: A0A3P3Z298
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

420245:LBRM 03 0050
gene id: 420245:LBRM_03_0050
uniprot id: A0A3P3YWY1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

420245:LBRM 35 7280
gene id: 420245:LBRM_35_7280
uniprot id: A0A3P3ZJW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

420245:LBRM 25 1390
gene id: 420245:LBRM_25_1390
uniprot id: A0A3P3Z8L7
names: Similarity
messages: Belongs to the SLBP family.

420245:LBRM 27 1520
gene id: 420245:LBRM_27_1520
uniprot id: A0A3P3Z9Z8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

420245:LBRM 07 1220
gene id: 420245:LBRM_07_1220
uniprot id: A0A3P3YYR3
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

420245:LBRM 34 0170
gene id: 420245:LBRM_34_0170
uniprot id: A0A3P3ZGJ4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

420245:LBRM 34 3640
gene id: 420245:LBRM_34_3640
uniprot id: A0A3P3ZH98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

420245:LBRM 23 1860
gene id: 420245:LBRM_23_1860
uniprot id: A0A3P3YXR6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 22 0960
gene id: 420245:LBRM_22_0960
uniprot id: A0A3P3Z6T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures.
messages: Nucleus

420245:LBRM 07 1070
gene id: 420245:LBRM_07_1070
uniprot id: A0A3P3YYM8
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: Monomer.

420245:LBRM 27 0660
gene id: 420245:LBRM_27_0660
uniprot id: A0A3P3Z9V6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

420245:LBRM 34 3140
gene id: 420245:LBRM_34_3140
uniprot id: A0A3P3ZHQ9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

420245:LBRM 09 1400
gene id: 420245:LBRM_09_1400
uniprot id: A0A3P3YZE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 34 4750
gene id: 420245:LBRM_34_4750
uniprot id: A0A3P3ZHL3
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 35 1200
gene id: 420245:LBRM_35_1200
uniprot id: A0A3P3ZIB2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

420245:LBRM 28 0580
gene id: 420245:LBRM_28_0580
uniprot id: A0A3P3ZAN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

420245:LBRM 33 3460
gene id: 420245:LBRM_33_3460
uniprot id: A0A3P3ZGR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

420245:LBRM 29 2720
gene id: 420245:LBRM_29_2720
uniprot id: A0A3P3Z0Q3
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

420245:LBRM 14 1330
gene id: 420245:LBRM_14_1330
uniprot id: A0A3P3Z1J5
names: Similarity
messages: Belongs to the enolase family.

420245:LBRM 30 1610
gene id: 420245:LBRM_30_1610
uniprot id: A0A3P3ZCL0
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

420245:LBRM 26 1890
gene id: 420245:LBRM_26_1890
uniprot id: A0A3P3Z9D9
names: Similarity
messages: Belongs to the SCO1/2 family.

420245:LBRM 05 0320
gene id: 420245:LBRM_05_0320
uniprot id: A0A3P3YXQ8
names: Similarity
messages: Belongs to the MCM family.

420245:LBRM 10 1070
gene id: 420245:LBRM_10_1070
uniprot id: A0A3P3YZT5
names: Similarity
messages: Belongs to the histone H3 family.

420245:LBRM 05 1140
gene id: 420245:LBRM_05_1140
uniprot id: A0A3P3YXW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

420245:LBRM 33 2260
gene id: 420245:LBRM_33_2260
uniprot id: A0A3P3ZGA6
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 03 0260
gene id: 420245:LBRM_03_0260
uniprot id: A0A3P3YX11
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

420245:LBRM 18 0420
gene id: 420245:LBRM_18_0420
uniprot id: A0A3P3Z373
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 29 2900
gene id: 420245:LBRM_29_2900
uniprot id: A0A3P3YXZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 32 1490
gene id: 420245:LBRM_32_1490
uniprot id: A0A3P3ZF48
names: Similarity
messages: Belongs to the DeSI family.

420245:LBRM 34 3160
gene id: 420245:LBRM_34_3160
uniprot id: A0A3P3ZH53
names: Similarity
messages: Belongs to the activator 1 small subunits family.

420245:LBRM 34 0600
gene id: 420245:LBRM_34_0600
uniprot id: A0A3P3ZGD7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

420245:LBRM 30 1130
gene id: 420245:LBRM_30_1130
uniprot id: A0A3P3ZCH8
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 33 1630
gene id: 420245:LBRM_33_1630
uniprot id: A0A3P3ZFZ3
names: Similarity
messages: Belongs to the complex I LYR family.

420245:LBRM 32 2450
gene id: 420245:LBRM_32_2450
uniprot id: A0A3P3ZEQ2
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

420245:LBRM 04 0950
gene id: 420245:LBRM_04_0950
uniprot id: A0A3P3YXH2
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

420245:LBRM 22 1040
gene id: 420245:LBRM_22_1040
uniprot id: A0A3P3Z6S8
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

420245:LBRM 19 1360
gene id: 420245:LBRM_19_1360
uniprot id: A0A3P3Z3X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

420245:LBRM 35 1010
gene id: 420245:LBRM_35_1010
uniprot id: A0A3P3ZI94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

420245:LBRM 24 0420
gene id: 420245:LBRM_24_0420
uniprot id: A0A3P3Z7J1
names: Similarity
messages: Belongs to the peptidase C12 family.

420245:LBRM 10 0020
gene id: 420245:LBRM_10_0020
uniprot id: A0A3P3YZK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

420245:LBRM 35 3140
gene id: 420245:LBRM_35_3140
uniprot id: A0A3P3ZIN6
names: Similarity
messages: Belongs to the PHF5 family.

420245:LBRM 18 0380
gene id: 420245:LBRM_18_0380
uniprot id: A0A3P3Z3F3
names: Similarity
messages: Belongs to the peptidase C13 family.

420245:LBRM 34 0260
gene id: 420245:LBRM_34_0260
uniprot id: A0A3P3ZGE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Mitochondrion inner membrane

420245:LBRM 28 2760
gene id: 420245:LBRM_28_2760
uniprot id: A0A3P3ZBI3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

420245:LBRM 35 0420
gene id: 420245:LBRM_35_0420
uniprot id: A0A3P3ZHX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

420245:LBRM 24 0650
gene id: 420245:LBRM_24_0650
uniprot id: A0A3P3Z7L5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 30 0390
gene id: 420245:LBRM_30_0390
uniprot id: A0A3P3ZC98
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 27 1800
gene id: 420245:LBRM_27_1800
uniprot id: A0A3P3ZA62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

420245:LBRM 29 2360
gene id: 420245:LBRM_29_2360
uniprot id: A0A3P3ZC13
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 35 5520
gene id: 420245:LBRM_35_5520
uniprot id: A0A3P3ZJD2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

420245:LBRM 17 0160
gene id: 420245:LBRM_17_0160
uniprot id: A0A3P3Z2P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

420245:LBRM 15 1560
gene id: 420245:LBRM_15_1560
uniprot id: A0A3P3Z214
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 06 0630
gene id: 420245:LBRM_06_0630
uniprot id: A0A3P3YYE6
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.

420245:LBRM 32 0120
gene id: 420245:LBRM_32_0120
uniprot id: A0A3P3ZE54
names: Similarity
messages: Belongs to the syntaxin family.

420245:LBRM 32 3270
gene id: 420245:LBRM_32_3270
uniprot id: A0A3P3ZEY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 11 0490
gene id: 420245:LBRM_11_0490
uniprot id: A0A3P3Z0B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer.

420245:LBRM 34 5310
gene id: 420245:LBRM_34_5310
uniprot id: A0A3P3ZI69
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

420245:LBRM 31 0040
gene id: 420245:LBRM_31_0040
uniprot id: A0A3P3ZD80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

420245:LBRM 12 0910
gene id: 420245:LBRM_12_0910
uniprot id: A0A3P3Z0W9
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 35 2920
gene id: 420245:LBRM_35_2920
uniprot id: A0A3P3ZIL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

420245:LBRM 34 1700
gene id: 420245:LBRM_34_1700
uniprot id: A0A3P3ZGR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus

420245:LBRM 17 0260
gene id: 420245:LBRM_17_0260
uniprot id: A0A3P3Z2Q8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 26 2320
gene id: 420245:LBRM_26_2320
uniprot id: A0A3P3Z9H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

420245:LBRM 35 2130
gene id: 420245:LBRM_35_2130
uniprot id: A0A3P3ZID9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

420245:LBRM 28 3070
gene id: 420245:LBRM_28_3070
uniprot id: A0A3P3ZB85
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

420245:LBRM 09 0920
gene id: 420245:LBRM_09_0920
uniprot id: A0A3P3YZ86
names: Similarity
messages: Belongs to the MYG1 family.

420245:LBRM 16 0950
gene id: 420245:LBRM_16_0950
uniprot id: A0A3P3Z2B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

420245:LBRM 25 0580
gene id: 420245:LBRM_25_0580
uniprot id: A0A3P3Z8A2
names: Function
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

420245:LBRM 15 1050
gene id: 420245:LBRM_15_1050
uniprot id: A0A3P3Z208
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

420245:LBRM 26 2410
gene id: 420245:LBRM_26_2410
uniprot id: A0A3P3Z9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

420245:LBRM 13 0920
gene id: 420245:LBRM_13_0920
uniprot id: A0A3P3Z177
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

420245:LBRM 13 1000
gene id: 420245:LBRM_13_1000
uniprot id: A0A3P3Z109
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

420245:LBRM 23 0400
gene id: 420245:LBRM_23_0400
uniprot id: A0A3P3Z733
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

420245:LBRM 12 0480
gene id: 420245:LBRM_12_0480
uniprot id: A0A3P3Z0I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

420245:LBRM 34 3360
gene id: 420245:LBRM_34_3360
uniprot id: A0A3P3ZHS7
names: Similarity
messages: Belongs to the XPC family.

420245:LBRM 13 1150
gene id: 420245:LBRM_13_1150
uniprot id: A0A3P3Z123
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

420245:LBRM 30 0130
gene id: 420245:LBRM_30_0130
uniprot id: A0A3P3ZC92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
messages: Homodimer.
messages: Peroxisome

420245:LBRM 30 2880
gene id: 420245:LBRM_30_2880
uniprot id: A0A3P3ZCZ8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

420245:LBRM 32 3820
gene id: 420245:LBRM_32_3820
uniprot id: A0A3P3ZFD7
names: Similarity
messages: Belongs to the GAMAD family.

420245:LBRM 12 0630
gene id: 420245:LBRM_12_0630
uniprot id: A0A3P3Z0K0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

420245:LBRM 26 2620
gene id: 420245:LBRM_26_2620
uniprot id: A0A3P3Z9U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 13 0990
gene id: 420245:LBRM_13_0990
uniprot id: A0A3P3Z0Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

420245:LBRM 33 1620
gene id: 420245:LBRM_33_1620
uniprot id: A0A3P3ZFQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

420245:LBRM 21 0740
gene id: 420245:LBRM_21_0740
uniprot id: A0A3P3Z619
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

420245:LBRM 09 0160
gene id: 420245:LBRM_09_0160
uniprot id: A0A3P3YZ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

420245:LBRM 30 0370
gene id: 420245:LBRM_30_0370
uniprot id: A0A3P3ZGI0
names: Subcellular Location Annotation
messages: trans-Golgi network

420245:LBRM 35 0600
gene id: 420245:LBRM_35_0600
uniprot id: A0A3P3ZHZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 11 0920
gene id: 420245:LBRM_11_0920
uniprot id: A0A3P3Z097
names: Similarity
messages: Belongs to the WD repeat SEC31 family.

420245:LBRM 15 1160
gene id: 420245:LBRM_15_1160
uniprot id: A0A3P3Z207
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

420245:LBRM 24 1210
gene id: 420245:LBRM_24_1210
uniprot id: A0A3P3Z7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

420245:LBRM 13 0220
gene id: 420245:LBRM_13_0220
uniprot id: A0A3P3Z0S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

420245:LBRM 14 0320
gene id: 420245:LBRM_14_0320
uniprot id: A0A3P3Z1B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.
messages: Membrane

420245:LBRM 24 1230
gene id: 420245:LBRM_24_1230
uniprot id: A0A3P3Z7S0
names: Similarity
messages: Belongs to the SUI1 family.

420245:LBRM 23 0840
gene id: 420245:LBRM_23_0840
uniprot id: A0A3P3Z741
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

420245:LBRM 10 0070
gene id: 420245:LBRM_10_0070
uniprot id: A0A3P3YZH1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

420245:LBRM 08 0340
gene id: 420245:LBRM_08_0340
uniprot id: A0A3P3YYR7
names: Similarity
messages: Belongs to the isochorismatase family.

420245:LBRM 06 0320
gene id: 420245:LBRM_06_0320
uniprot id: A0A3P3YY32
names: Similarity
messages: Belongs to the peptidase S9A family.

420245:LBRM 26 0400
gene id: 420245:LBRM_26_0400
uniprot id: A0A3P3Z931
names: Similarity
messages: Belongs to the IST1 family.

420245:LBRM 34 2150
gene id: 420245:LBRM_34_2150
uniprot id: A0A3P3ZHE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KMP-11 family.
messages: Monomer.
messages: cytoskeleton

420245:LBRM 21 1920
gene id: 420245:LBRM_21_1920
uniprot id: A0A3P3Z6E1
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

420245:LBRM 21 1310
gene id: 420245:LBRM_21_1310
uniprot id: A0A3P3Z690
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 10 0960
gene id: 420245:LBRM_10_0960
uniprot id: A0A3P3Z048
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

420245:LBRM 34 2950
gene id: 420245:LBRM_34_2950
uniprot id: A0A3P3ZH37
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

420245:LBRM 29 1530
gene id: 420245:LBRM_29_1530
uniprot id: A0A3P3ZBR9
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

420245:LBRM 19 1610
gene id: 420245:LBRM_19_1610
uniprot id: A0A3P3Z3Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

420245:LBRM 34 4620
gene id: 420245:LBRM_34_4620
uniprot id: A0A3P3ZHJ6
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 28 0040
gene id: 420245:LBRM_28_0040
uniprot id: A0A3P3ZAC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

420245:LBRM 27 0200
gene id: 420245:LBRM_27_0200
uniprot id: A0A3P3Z9V7
names: Similarity
messages: Belongs to the peptidase T1A family.

420245:LBRM 24 1970
gene id: 420245:LBRM_24_1970
uniprot id: A0A3P3Z7Z9
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 35 0550
gene id: 420245:LBRM_35_0550
uniprot id: A0A3P3ZIE9
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

420245:LBRM 32 0690
gene id: 420245:LBRM_32_0690
uniprot id: A0A3P3ZEN0
names: Similarity
messages: Belongs to the WD repeat SEC13 family.

420245:LBRM 31 0270
gene id: 420245:LBRM_31_0270
uniprot id: A0A3P3ZDC0
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

420245:LBRM 18 1160
gene id: 420245:LBRM_18_1160
uniprot id: A0A3P3Z3E9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 25 0800
gene id: 420245:LBRM_25_0800
uniprot id: A0A3P3Z8J5
names: Similarity
messages: Belongs to the SLBP family.

420245:LBRM 16 0210
gene id: 420245:LBRM_16_0210
uniprot id: A0A3P3Z2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 18 1180
gene id: 420245:LBRM_18_1180
uniprot id: A0A3P3Z3F1
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 16 1530
gene id: 420245:LBRM_16_1530
uniprot id: A0A3P3Z2J9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 04 0500
gene id: 420245:LBRM_04_0500
uniprot id: A0A3P3YXC4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

420245:LBRM 08 0150
gene id: 420245:LBRM_08_0150
uniprot id: A0A3P3YYQ1
names: Similarity
messages: Belongs to the XPF family.

420245:LBRM 21 0810
gene id: 420245:LBRM_21_0810
uniprot id: A0A3P3Z624
names: Function
names: Similarity
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.

420245:LBRM 35 1060
gene id: 420245:LBRM_35_1060
uniprot id: A0A3P3ZIL1
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

420245:LBRM 05 0060
gene id: 420245:LBRM_05_0060
uniprot id: A0A3P3YXK6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Nucleus
messages: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport.
messages: The vault ribonucleoprotein particle is a huge (400 A x 670 A) cage structure of 12.9 MDa. It consists of a dimer of half-vaults, with each half-vault comprising 39 identical major vault protein (MVP) chains, PARP4 and one or more vault RNAs (vRNAs).

420245:LBRM 06 0040
gene id: 420245:LBRM_06_0040
uniprot id: A0A3P3YY69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

420245:LBRM 31 2960
gene id: 420245:LBRM_31_2960
uniprot id: A0A3P3ZE39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

420245:LBRM 29 2280
gene id: 420245:LBRM_29_2280
uniprot id: A0A3P3ZC16
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

420245:LBRM 35 2580
gene id: 420245:LBRM_35_2580
uniprot id: A0A3P3ZIP8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

420245:LBRM 06 0830
gene id: 420245:LBRM_06_0830
uniprot id: A0A3P3YY75
names: Function
names: Similarity
messages: Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.
messages: In the C-terminal section; belongs to the thymidylate synthase family.
messages: In the N-terminal section; belongs to the dihydrofolate reductase family.

420245:LBRM 09 0490
gene id: 420245:LBRM_09_0490
uniprot id: A0A3P3YZ51
names: Similarity
messages: Belongs to the PPP phosphatase family.

420245:LBRM 29 1410
gene id: 420245:LBRM_29_1410
uniprot id: A0A3P3ZBQ3
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

420245:LBRM 01 0300
gene id: 420245:LBRM_01_0300
uniprot id: A0A3P3YWH5
names: Similarity
messages: Belongs to the thioredoxin family.

420245:LBRM 34 4230
gene id: 420245:LBRM_34_4230
uniprot id: A0A3P3ZHV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

420245:LBRM 27 1440
gene id: 420245:LBRM_27_1440
uniprot id: A0A3P3Z9Y2
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

420245:LBRM 14 0920
gene id: 420245:LBRM_14_0920
uniprot id: A0A3P3Z1G3
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

420245:LBRM 35 1780
gene id: 420245:LBRM_35_1780
uniprot id: A0A3P3ZIG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

420245:LBRM 23 1180
gene id: 420245:LBRM_23_1180
uniprot id: A0A3P3Z783
names: Function
names: Similarity
messages: Belongs to the BMT2 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase.

420245:LBRM 15 1260
gene id: 420245:LBRM_15_1260
uniprot id: A0A3P3Z2A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

420245:LBRM 35 5400
gene id: 420245:LBRM_35_5400
uniprot id: A0A3P3ZJJ1
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 28 1250
gene id: 420245:LBRM_28_1250
uniprot id: A0A3P3ZAZ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Vacuole membrane

420245:LBRM 19 0440
gene id: 420245:LBRM_19_0440
uniprot id: A0A3P3Z3M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

420245:LBRM 34 1360
gene id: 420245:LBRM_34_1360
uniprot id: A0A3P3ZH28
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

420245:LBRM 32 3680
gene id: 420245:LBRM_32_3680
uniprot id: A0A3P3ZF65
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

420245:LBRM 23 0580
gene id: 420245:LBRM_23_0580
uniprot id: A0A3P3Z720
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

420245:LBRM 16 0560
gene id: 420245:LBRM_16_0560
uniprot id: A0A3P3Z2A0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

420245:LBRM 32 4080
gene id: 420245:LBRM_32_4080
uniprot id: A0A3P3ZF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

420245:LBRM 21 0530
gene id: 420245:LBRM_21_0530
uniprot id: A0A3P3Z694
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

420245:LBRM 13 0470
gene id: 420245:LBRM_13_0470
uniprot id: A0A3P3Z0W4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

420245:LBRM 33 1020
gene id: 420245:LBRM_33_1020
uniprot id: A0A3P3ZFI6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

420245:LBRM 31 1550
gene id: 420245:LBRM_31_1550
uniprot id: A0A3P3ZDL9
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 35 6350
gene id: 420245:LBRM_35_6350
uniprot id: A0A3P3ZJZ6
names: Similarity
messages: Belongs to the COG2 family.

420245:LBRM 14 0880
gene id: 420245:LBRM_14_0880
uniprot id: A0A3P3Z1E4
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

420245:LBRM 04 1030
gene id: 420245:LBRM_04_1030
uniprot id: A0A3P3YXH9
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 34 3270
gene id: 420245:LBRM_34_3270
uniprot id: A0A3P3ZHP9
names: Similarity
messages: Belongs to the THADA family.

420245:LBRM 27 1880
gene id: 420245:LBRM_27_1880
uniprot id: A0A3P3ZA21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

420245:LBRM 30 3690
gene id: 420245:LBRM_30_3690
uniprot id: A0A3P3ZDC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

420245:LBRM 19 1170
gene id: 420245:LBRM_19_1170
uniprot id: A0A3P3Z435
names: Similarity
messages: Belongs to the ATG8 family.

420245:LBRM 13 0930
gene id: 420245:LBRM_13_0930
uniprot id: A0A3P3Z100
names: Similarity
messages: Belongs to the RMD1/sif2 family.

420245:LBRM 19 1430
gene id: 420245:LBRM_19_1430
uniprot id: A0A3P3Z3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 24 2320
gene id: 420245:LBRM_24_2320
uniprot id: A0A3P3Z860
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

420245:LBRM 35 1380
gene id: 420245:LBRM_35_1380
uniprot id: A0A3P3ZI54
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

420245:LBRM 30 1700
gene id: 420245:LBRM_30_1700
uniprot id: A0A3P3ZCM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 25 1030
gene id: 420245:LBRM_25_1030
uniprot id: A0A3P3Z8J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with a member of the SLX4 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

420245:LBRM 35 1050
gene id: 420245:LBRM_35_1050
uniprot id: A0A3P3ZIL1
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

420245:LBRM 33 2840
gene id: 420245:LBRM_33_2840
uniprot id: A0A3P3ZG54
names: Similarity
messages: Belongs to the peptidase M17 family.

420245:LBRM 29 1350
gene id: 420245:LBRM_29_1350
uniprot id: A0A3P3ZBX3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

420245:LBRM 32 0580
gene id: 420245:LBRM_32_0580
uniprot id: A0A3P3ZEV9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

420245:LBRM 35 1860
gene id: 420245:LBRM_35_1860
uniprot id: A0A3P3ZIT5
names: Function
names: Similarity
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.

420245:LBRM 25 1700
gene id: 420245:LBRM_25_1700
uniprot id: A0A3P3Z8W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

420245:LBRM 35 5610
gene id: 420245:LBRM_35_5610
uniprot id: A0A3P3ZJE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

420245:LBRM 17 0400
gene id: 420245:LBRM_17_0400
uniprot id: A0A3P3Z2S2
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 27 0670
gene id: 420245:LBRM_27_0670
uniprot id: A0A3P3Z9S4
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 07 0800
gene id: 420245:LBRM_07_0800
uniprot id: A0A3P3YYS9
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 34 1900
gene id: 420245:LBRM_34_1900
uniprot id: A0A3P3ZH12
names: Subcellular Location Annotation
messages: nucleolus

420245:LBRM 15 1530
gene id: 420245:LBRM_15_1530
uniprot id: A0A3P3Z261
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

420245:LBRM 19 0570
gene id: 420245:LBRM_19_0570
uniprot id: A0A3P3Z3N0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 19 0460
gene id: 420245:LBRM_19_0460
uniprot id: A0A3P3Z3K8
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 30 2950
gene id: 420245:LBRM_30_2950
uniprot id: A0A3P3ZD00
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

420245:LBRM 32 0130
gene id: 420245:LBRM_32_0130
uniprot id: A0A3P3ZE52
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

420245:LBRM 14 1280
gene id: 420245:LBRM_14_1280
uniprot id: A0A3P3Z4I8
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

420245:LBRM 34 5040
gene id: 420245:LBRM_34_5040
uniprot id: A0A3P3ZHN5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.

420245:LBRM 26 0040
gene id: 420245:LBRM_26_0040
uniprot id: A0A3P3Z918
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

420245:LBRM 30 0530
gene id: 420245:LBRM_30_0530
uniprot id: A0A3P3ZCB6
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

420245:LBRM 33 2590
gene id: 420245:LBRM_33_2590
uniprot id: A0A3P3ZG07
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

420245:LBRM 14 0350
gene id: 420245:LBRM_14_0350
uniprot id: A0A3P3Z1F0
names: Similarity
messages: Belongs to the threonine synthase family.

420245:LBRM 21 1280
gene id: 420245:LBRM_21_1280
uniprot id: A0A3P3Z6G4
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

420245:LBRM 28 2220
gene id: 420245:LBRM_28_2220
uniprot id: A0A3P3ZB82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

420245:LBRM 11 0320
gene id: 420245:LBRM_11_0320
uniprot id: A0A3P3Z054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

420245:LBRM 25 1810
gene id: 420245:LBRM_25_1810
uniprot id: A0A3P3Z8X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

420245:LBRM 22 0530
gene id: 420245:LBRM_22_0530
uniprot id: A0A3P3Z6W4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

420245:LBRM 16 1670
gene id: 420245:LBRM_16_1670
uniprot id: A0A3P3Z2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

420245:LBRM 26 0060
gene id: 420245:LBRM_26_0060
uniprot id: A0A3P3Z902
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 34 2040
gene id: 420245:LBRM_34_2040
uniprot id: A0A3P3ZHG8
names: Similarity
messages: Belongs to the synaptobrevin family.

420245:LBRM 27 1850
gene id: 420245:LBRM_27_1850
uniprot id: A0A3P3ZA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

420245:LBRM 34 0810
gene id: 420245:LBRM_34_0810
uniprot id: A0A3P3ZGI6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

420245:LBRM 18 0170
gene id: 420245:LBRM_18_0170
uniprot id: A0A3P3Z348
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

420245:LBRM 08 0160
gene id: 420245:LBRM_08_0160
uniprot id: A0A3P3YYQ5
names: Similarity
messages: Belongs to the PIGH family.

420245:LBRM 15 1510
gene id: 420245:LBRM_15_1510
uniprot id: A0A3P3Z255
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS1/PSF1 family.
messages: Nucleus

420245:LBRM 32 1150
gene id: 420245:LBRM_32_1150
uniprot id: A0A3P3ZED7
names: Similarity
messages: Belongs to the VPS29 family.

420245:LBRM 07 1060
gene id: 420245:LBRM_07_1060
uniprot id: A0A3P3YYM2
names: Similarity
messages: Belongs to the MIP18 family.

420245:LBRM 24 0780
gene id: 420245:LBRM_24_0780
uniprot id: A0A3P3Z7W4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

420245:LBRM 35 2600
gene id: 420245:LBRM_35_2600
uniprot id: A0A3P3ZII3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.

420245:LBRM 24 2390
gene id: 420245:LBRM_24_2390
uniprot id: A0A3P3Z8C4
names: Similarity
messages: Belongs to the UPF0610 family.

420245:LBRM 25 0790
gene id: 420245:LBRM_25_0790
uniprot id: A0A3P3Z8D3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

420245:LBRM 35 2250
gene id: 420245:LBRM_35_2250
uniprot id: A0A3P3ZIE8
names: Function
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

420245:LBRM 24 2330
gene id: 420245:LBRM_24_2330
uniprot id: A0A3P3Z826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane

420245:LBRM 28 0360
gene id: 420245:LBRM_28_0360
uniprot id: A0A3P3ZAF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Membrane

420245:LBRM 08 0890
gene id: 420245:LBRM_08_0890
uniprot id: A0A3P3YZ53
names: Subcellular Location Annotation
messages: cilium axoneme

420245:LBRM 24 0660
gene id: 420245:LBRM_24_0660
uniprot id: A0A3P3Z7K0
names: Similarity
messages: Belongs to the DeSI family.

420245:LBRM 11 0660
gene id: 420245:LBRM_11_0660
uniprot id: A0A3P3Z085
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 34 1650
gene id: 420245:LBRM_34_1650
uniprot id: A0A3P3ZGQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: cytoskeleton

420245:LBRM 16 1450
gene id: 420245:LBRM_16_1450
uniprot id: A0A3P3Z2I4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

420245:LBRM 21 0800
gene id: 420245:LBRM_21_0800
uniprot id: A0A3P3Z697
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

420245:LBRM 24 1350
gene id: 420245:LBRM_24_1350
uniprot id: A0A3P3Z7V8
names: Similarity
messages: Belongs to the TCTP family.

420245:LBRM 32 2000
gene id: 420245:LBRM_32_2000
uniprot id: A0A3P3ZEL6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

420245:LBRM 35 7380
gene id: 420245:LBRM_35_7380
uniprot id: A0A3P3ZJX3
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

420245:LBRM 31 0170
gene id: 420245:LBRM_31_0170
uniprot id: A0A3P3ZBX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

420245:LBRM 19 0740
gene id: 420245:LBRM_19_0740
uniprot id: A0A3P3Z3P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

420245:LBRM 11 1040
gene id: 420245:LBRM_11_1040
uniprot id: A0A3P3Z0B2
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 09 0720
gene id: 420245:LBRM_09_0720
uniprot id: A0A3P3YZD2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

420245:LBRM 23 1590
gene id: 420245:LBRM_23_1590
uniprot id: A0A3P3Z7B5
names: Similarity
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.

420245:LBRM 04 1230
gene id: 420245:LBRM_04_1230
uniprot id: A0A3P3YXJ8
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 28 2120
gene id: 420245:LBRM_28_2120
uniprot id: A0A3P3ZAY5
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 34 4170
gene id: 420245:LBRM_34_4170
uniprot id: A0A3P3ZHM3
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 15 1060
gene id: 420245:LBRM_15_1060
uniprot id: A0A3P3Z292
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

420245:LBRM 28 0220
gene id: 420245:LBRM_28_0220
uniprot id: A0A3P3ZAC8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 33 0290
gene id: 420245:LBRM_33_0290
uniprot id: A0A3P3ZG06
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

420245:LBRM 18 1330
gene id: 420245:LBRM_18_1330
uniprot id: A0A3P3Z3H0
names: Similarity
messages: Belongs to the PIH1 family.

420245:LBRM 34 4980
gene id: 420245:LBRM_34_4980
uniprot id: A0A3P3ZHN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

420245:LBRM 35 2070
gene id: 420245:LBRM_35_2070
uniprot id: A0A3P3ZIV7
names: Similarity
messages: Belongs to the CBF/MAK21 family.

420245:LBRM 27 0050
gene id: 420245:LBRM_27_0050
uniprot id: A0A3P3Z9W2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

420245:LBRM 29 1400
gene id: 420245:LBRM_29_1400
uniprot id: A0A3P3ZBS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: Nucleus

420245:LBRM 18 0510
gene id: 420245:LBRM_18_0510
uniprot id: A0A3P3Z3A1
names: Similarity
messages: Belongs to the peptidase S10 family.

420245:LBRM 35 6620
gene id: 420245:LBRM_35_6620
uniprot id: A0A3P3ZJQ4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

420245:LBRM 30 0830
gene id: 420245:LBRM_30_0830
uniprot id: A0A3P3ZCE5
names: Similarity
messages: Belongs to the GrpE family.

420245:LBRM 07 0560
gene id: 420245:LBRM_07_0560
uniprot id: A0A3P3YYJ0
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

420245:LBRM 28 3230
gene id: 420245:LBRM_28_3230
uniprot id: A0A3P3ZB86
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

420245:LBRM 31 1310
gene id: 420245:LBRM_31_1310
uniprot id: A0A3P3ZDH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

420245:LBRM 35 4170
gene id: 420245:LBRM_35_4170
uniprot id: A0A3P3ZJ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

420245:LBRM 10 1080
gene id: 420245:LBRM_10_1080
uniprot id: A0A3P3YZT5
names: Similarity
messages: Belongs to the histone H3 family.

420245:LBRM 32 3330
gene id: 420245:LBRM_32_3330
uniprot id: A0A3P3ZEZ6
names: Similarity
messages: Belongs to the PPP phosphatase family.

420245:LBRM 09 0850
gene id: 420245:LBRM_09_0850
uniprot id: A0A3P3YZD6
names: Similarity
messages: Belongs to the peptidase S9A family.

420245:LBRM 21 0820
gene id: 420245:LBRM_21_0820
uniprot id: A0A3P3Z6C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

420245:LBRM 02 0410
gene id: 420245:LBRM_02_0410
uniprot id: A0A3P3YWV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

420245:LBRM 35 2240
gene id: 420245:LBRM_35_2240
uniprot id: A0A3P3ZIX6
names: Function
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

420245:LBRM 24 2420
gene id: 420245:LBRM_24_2420
uniprot id: A0A3P3Z870
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

420245:LBRM 27 2630
gene id: 420245:LBRM_27_2630
uniprot id: A0A3P3ZAL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

420245:LBRM 35 2370
gene id: 420245:LBRM_35_2370
uniprot id: A0A3P3ZIF5
names: Similarity
messages: Belongs to the DEAD box helicase family.

420245:LBRM 15 0401
gene id: 420245:LBRM_15_0401
uniprot id: A0A3P3Z1R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: P1 and P2 exist as dimers at the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

420245:LBRM 27 2470
gene id: 420245:LBRM_27_2470
uniprot id: A0A3P3ZA99
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

420245:LBRM 27 1590
gene id: 420245:LBRM_27_1590
uniprot id: A0A3P3Z9Z1
names: Similarity
messages: Belongs to the CBF/MAK21 family.

420245:LBRM 10 0620
gene id: 420245:LBRM_10_0620
uniprot id: A0A3P3YZP6
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

420245:LBRM 23 0740
gene id: 420245:LBRM_23_0740
uniprot id: A0A3P3Z6Y6
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 25 0480
gene id: 420245:LBRM_25_0480
uniprot id: A0A3P3Z8F8
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 28 0850
gene id: 420245:LBRM_28_0850
uniprot id: A0A3P3ZAX1
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

420245:LBRM 21 1680
gene id: 420245:LBRM_21_1680
uniprot id: A0A3P3Z6C5
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

420245:LBRM 35 0190
gene id: 420245:LBRM_35_0190
uniprot id: A0A3P3ZHU0
names: Similarity
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.

420245:LBRM 24 2290
gene id: 420245:LBRM_24_2290
uniprot id: A0A3P3Z8B3
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

420245:LBRM 14 0650
gene id: 420245:LBRM_14_0650
uniprot id: A0A3P3Z1D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

420245:LBRM 35 2040
gene id: 420245:LBRM_35_2040
uniprot id: A0A3P3ZIC2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G.

420245:LBRM 32 3210
gene id: 420245:LBRM_32_3210
uniprot id: A0A3P3ZF18
names: Similarity
messages: Belongs to the NDK family.

420245:LBRM 24 1560
gene id: 420245:LBRM_24_1560
uniprot id: A0A3P3Z7Z4
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

420245:LBRM 35 4690
gene id: 420245:LBRM_35_4690
uniprot id: A0A3P3ZJH3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

420245:LBRM 34 3990
gene id: 420245:LBRM_34_3990
uniprot id: A0A3P3ZHE0
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 29 2620
gene id: 420245:LBRM_29_2620
uniprot id: A0A3P3ZC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

420245:LBRM 21 1320
gene id: 420245:LBRM_21_1320
uniprot id: A0A3P3Z674
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

420245:LBRM 30 0380
gene id: 420245:LBRM_30_0380
uniprot id: A0A3P3ZCA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus

420245:LBRM 05 0290
gene id: 420245:LBRM_05_0290
uniprot id: A0A3P3YXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

420245:LBRM 21 1300
gene id: 420245:LBRM_21_1300
uniprot id: A0A3P3Z6H1
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

420245:LBRM 18 0520
gene id: 420245:LBRM_18_0520
uniprot id: A0A3P3Z395
names: Similarity
messages: Belongs to the TBCB family.

420245:LBRM 04 0600
gene id: 420245:LBRM_04_0600
uniprot id: A0A3P3YXD1
names: Similarity
messages: Belongs to the TTC21 family.

420245:LBRM 28 2340
gene id: 420245:LBRM_28_2340
uniprot id: A0A3P3ZB56
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

420245:LBRM 34 0640
gene id: 420245:LBRM_34_0640
uniprot id: A0A3P3ZGF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

420245:LBRM 35 3690
gene id: 420245:LBRM_35_3690
uniprot id: A0A3P3ZIV5
names: Similarity
messages: Belongs to the NipSnap family.

420245:LBRM 34 2441
gene id: 420245:LBRM_34_2441
uniprot id: A0A3P3ZHJ8
names: Similarity
messages: Belongs to the YOS1 family.

420245:LBRM 30 2300
gene id: 420245:LBRM_30_2300
uniprot id: A0A3P3ZCU4
names: Similarity
messages: Belongs to the group II decarboxylase family.

420245:LBRM 25 1930
gene id: 420245:LBRM_25_1930
uniprot id: A0A3P3Z8S3
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 35 6690
gene id: 420245:LBRM_35_6690
uniprot id: A0A3P3ZJQ6
names: Similarity
messages: Belongs to the TMA16 family.

420245:LBRM 30 0940
gene id: 420245:LBRM_30_0940
uniprot id: A0A3P3ZCH2
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

420245:LBRM 34 4390
gene id: 420245:LBRM_34_4390
uniprot id: A0A3P3ZHH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.
messages: Membrane

420245:LBRM 26 0250
gene id: 420245:LBRM_26_0250
uniprot id: A0A3P3Z8W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

420245:LBRM 27 1140
gene id: 420245:LBRM_27_1140
uniprot id: A0A3P3Z9V1
names: Similarity
messages: Belongs to the AAA ATPase family.

420245:LBRM 28 1080
gene id: 420245:LBRM_28_1080
uniprot id: A0A3P3ZAU5
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

420245:LBRM 18 1700
gene id: 420245:LBRM_18_1700
uniprot id: A0A3P3Z3L2
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

420245:LBRM 32 3670
gene id: 420245:LBRM_32_3670
uniprot id: A0A3P3ZF19
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

420245:LBRM 28 2570
gene id: 420245:LBRM_28_2570
uniprot id: A0A3P3ZBG8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 30 1190
gene id: 420245:LBRM_30_1190
uniprot id: A0A3P3ZCI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.

420245:LBRM 35 1840
gene id: 420245:LBRM_35_1840
uniprot id: A0A3P3ZIA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

420245:LBRM 06 0410
gene id: 420245:LBRM_06_0410
uniprot id: A0A3P3YY41
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

420245:LBRM 22 1220
gene id: 420245:LBRM_22_1220
uniprot id: A0A3P3Z6U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

420245:LBRM 32 3610
gene id: 420245:LBRM_32_3610
uniprot id: A0A3P3ZF11
names: Similarity
messages: Belongs to the cyclin family.

420245:LBRM 22 0030
gene id: 420245:LBRM_22_0030
uniprot id: A0A3P3YXF0
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

420245:LBRM 26 0200
gene id: 420245:LBRM_26_0200
uniprot id: A0A3P3Z997
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.
messages: Cytoplasm

420245:LBRM 27 2210
gene id: 420245:LBRM_27_2210
uniprot id: A0A3P3ZA52
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

420245:LBRM 35 3450
gene id: 420245:LBRM_35_3450
uniprot id: A0A3P3ZIT2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

420245:LBRM 34 3350
gene id: 420245:LBRM_34_3350
uniprot id: A0A3P3ZH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

420245:LBRM 30 0360
gene id: 420245:LBRM_30_0360
uniprot id: A0A3P3ZFY8
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 06 1030
gene id: 420245:LBRM_06_1030
uniprot id: A0A3P3YYC0
names: Similarity
messages: Belongs to the protein disulfide isomerase family.

420245:LBRM 33 0850
gene id: 420245:LBRM_33_0850
uniprot id: A0A3P3Z6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Vacuole membrane

420245:LBRM 35 2390
gene id: 420245:LBRM_35_2390
uniprot id: A0A3P3ZIG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

420245:LBRM 34 5270
gene id: 420245:LBRM_34_5270
uniprot id: A0A3P3ZHT0
names: Subunit
messages: Homooctamer. Dimer of tetramers.

420245:LBRM 18 1210
gene id: 420245:LBRM_18_1210
uniprot id: A0A3P3Z3F2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

420245:LBRM 21 0990
gene id: 420245:LBRM_21_0990
uniprot id: A0A3P3Z646
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

420245:LBRM 34 4450
gene id: 420245:LBRM_34_4450
uniprot id: A0A3P3ZI12
names: Similarity
messages: Belongs to the p23/wos2 family.

420245:LBRM 07 0140
gene id: 420245:LBRM_07_0140
uniprot id: A0A3P3YYN0
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 25 1160
gene id: 420245:LBRM_25_1160
uniprot id: A0A3P3Z8M4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

420245:LBRM 16 0010
gene id: 420245:LBRM_16_0010
uniprot id: A0A3P3Z2D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

420245:LBRM 30 2310
gene id: 420245:LBRM_30_2310
uniprot id: A0A3P3ZDF7
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 06 0870
gene id: 420245:LBRM_06_0870
uniprot id: A0A3P3YY81
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

420245:LBRM 24 2340
gene id: 420245:LBRM_24_2340
uniprot id: A0A3P3Z833
names: Subcellular Location Annotation
messages: nucleolus

420245:LBRM 13 1520
gene id: 420245:LBRM_13_1520
uniprot id: A0A3P3Z1A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

420245:LBRM 34 0050
gene id: 420245:LBRM_34_0050
uniprot id: A0A3P3ZHT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 34 5180
gene id: 420245:LBRM_34_5180
uniprot id: A0A3P3ZI92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Nucleus

420245:LBRM 26 1660
gene id: 420245:LBRM_26_1660
uniprot id: A0A3P3Z9D6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

420245:LBRM 11 0940
gene id: 420245:LBRM_11_0940
uniprot id: A0A3P3Z0I3
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 32 1350
gene id: 420245:LBRM_32_1350
uniprot id: A0A3P3ZEH6
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

420245:LBRM 09 0870
gene id: 420245:LBRM_09_0870
uniprot id: A0A3P3YZJ4
names: Similarity
messages: Belongs to the WD repeat WDR91 family.

420245:LBRM 23 0280
gene id: 420245:LBRM_23_0280
uniprot id: A0A3P3Z788
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 31 2130
gene id: 420245:LBRM_31_2130
uniprot id: A0A3P3ZDU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome.
messages: Cytoplasm
messages: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Part of the 60S ribosomal subunit.

420245:LBRM 27 2480
gene id: 420245:LBRM_27_2480
uniprot id: A0A3P3ZA85
names: Similarity
messages: Belongs to the SPT5 family.

420245:LBRM 25 1620
gene id: 420245:LBRM_25_1620
uniprot id: A0A3P3Z8V4
names: Similarity
messages: Belongs to the PP2C family.

420245:LBRM 02 0210
gene id: 420245:LBRM_02_0210
uniprot id: A0A3P3YWT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Membrane

420245:LBRM 24 1200
gene id: 420245:LBRM_24_1200
uniprot id: A0A3P3Z832
names: Similarity
messages: Belongs to the SURF6 family.

420245:LBRM 35 6050
gene id: 420245:LBRM_35_6050
uniprot id: A0A3P3ZJI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

420245:LBRM 19 0760
gene id: 420245:LBRM_19_0760
uniprot id: A0A3P3Z3Q0
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

420245:LBRM 34 3770
gene id: 420245:LBRM_34_3770
uniprot id: A0A3P3ZHC5
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

420245:LBRM 27 0940
gene id: 420245:LBRM_27_0940
uniprot id: A0A3P3Z9U3
names: Subcellular Location Annotation
messages: cilium axoneme

420245:LBRM 33 2320
gene id: 420245:LBRM_33_2320
uniprot id: A0A3P3ZGK9
names: Subcellular Location Annotation
messages: nuclear pore complex

420245:LBRM 19 0190
gene id: 420245:LBRM_19_0190
uniprot id: A0A3P3Z012
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

420245:LBRM 21 0310
gene id: 420245:LBRM_21_0310
uniprot id: A0A3P3Z5Y1
names: Similarity
messages: Belongs to the hexokinase family.

420245:LBRM 33 2170
gene id: 420245:LBRM_33_2170
uniprot id: A0A3P3ZGA1
names: Similarity
messages: Belongs to the CEP43 family.

420245:LBRM 28 2480
gene id: 420245:LBRM_28_2480
uniprot id: A0A3P3ZB29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

420245:LBRM 23 1640
gene id: 420245:LBRM_23_1640
uniprot id: A0A3P3Z7L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

420245:LBRM 31 2920
gene id: 420245:LBRM_31_2920
uniprot id: A0A3P3ZDY1
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

420245:LBRM 25 0210
gene id: 420245:LBRM_25_0210
uniprot id: A0A3P3Z872
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 34 1310
gene id: 420245:LBRM_34_1310
uniprot id: A0A3P3ZGM7
names: Similarity
messages: Belongs to the peptidase C64 family.

420245:LBRM 35 5990
gene id: 420245:LBRM_35_5990
uniprot id: A0A3P3ZK14
names: Function
messages: Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

420245:LBRM 35 4110
gene id: 420245:LBRM_35_4110
uniprot id: A0A3P3ZIZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

420245:LBRM 19 1770
gene id: 420245:LBRM_19_1770
uniprot id: A0A3P3Z425
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 27 2400
gene id: 420245:LBRM_27_2400
uniprot id: A0A3P3ZAE7
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

420245:LBRM 16 1360
gene id: 420245:LBRM_16_1360
uniprot id: A0A3P3Z2H8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

420245:LBRM 19 0490
gene id: 420245:LBRM_19_0490
uniprot id: A0A3P3Z3N3
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 21 0120
gene id: 420245:LBRM_21_0120
uniprot id: A0A3P3Z5V8
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 34 2750
gene id: 420245:LBRM_34_2750
uniprot id: A0A3P3ZH17
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

420245:LBRM 23 1760
gene id: 420245:LBRM_23_1760
uniprot id: A0A3P3Z7M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

420245:LBRM 35 3210
gene id: 420245:LBRM_35_3210
uniprot id: A0A3P3ZJ74
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

420245:LBRM 29 0630
gene id: 420245:LBRM_29_0630
uniprot id: A0A3P3ZBH3
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 35 4750
gene id: 420245:LBRM_35_4750
uniprot id: A0A3P3ZJL9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

420245:LBRM 28 2090
gene id: 420245:LBRM_28_2090
uniprot id: A0A3P3ZB26
names: Similarity
messages: Belongs to the PDCD5 family.

420245:LBRM 32 0650
gene id: 420245:LBRM_32_0650
uniprot id: A0A3P3ZE93
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

420245:LBRM 30 2320
gene id: 420245:LBRM_30_2320
uniprot id: A0A3P3ZD05
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

420245:LBRM 33 0180
gene id: 420245:LBRM_33_0180
uniprot id: A0A3P3ZFB4
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 29 1390
gene id: 420245:LBRM_29_1390
uniprot id: A0A3P3ZBP7
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

420245:LBRM 35 3430
gene id: 420245:LBRM_35_3430
uniprot id: A0A3P3ZIS4
names: Similarity
messages: Belongs to the 14-3-3 family.

420245:LBRM 07 0280
gene id: 420245:LBRM_07_0280
uniprot id: A0A3P3YYE9
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

420245:LBRM 33 0160
gene id: 420245:LBRM_33_0160
uniprot id: A0A3P3ZFK6
names: Similarity
messages: Belongs to the IWR1/SLC7A6OS family.

420245:LBRM 24 2210
gene id: 420245:LBRM_24_2210
uniprot id: A0A3P3Z818
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

420245:LBRM 18 1100
gene id: 420245:LBRM_18_1100
uniprot id: A0A3P3Z3E0
names: Similarity
messages: Belongs to the oxoprolinase family.

420245:LBRM 29 0640
gene id: 420245:LBRM_29_0640
uniprot id: A0A3P3ZBI9
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 21 1150
gene id: 420245:LBRM_21_1150
uniprot id: A0A3P3Z655
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 14 1490
gene id: 420245:LBRM_14_1490
uniprot id: A0A3P3Z1P1
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

420245:LBRM 24 2120
gene id: 420245:LBRM_24_2120
uniprot id: A0A3P3Z841
names: Similarity
messages: Belongs to the BolA/IbaG family.

420245:LBRM 30 3180
gene id: 420245:LBRM_30_3180
uniprot id: A0A3P3ZD29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane

420245:LBRM 33 2050
gene id: 420245:LBRM_33_2050
uniprot id: A0A3P3ZG91
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 29 0130
gene id: 420245:LBRM_29_0130
uniprot id: A0A3P3ZBC7
names: Similarity
messages: Belongs to the proteasome subunit S2 family.

420245:LBRM 35 6330
gene id: 420245:LBRM_35_6330
uniprot id: A0A3P3ZK42
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.

420245:LBRM 07 0150
gene id: 420245:LBRM_07_0150
uniprot id: A0A3P3YYD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

420245:LBRM 28 0750
gene id: 420245:LBRM_28_0750
uniprot id: A0A3P3ZAW1
names: Similarity
messages: Belongs to the SAS10 family.

420245:LBRM 13 0770
gene id: 420245:LBRM_13_0770
uniprot id: A0A3P3Z180
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

420245:LBRM 32 1100
gene id: 420245:LBRM_32_1100
uniprot id: A0A3P3ZED1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

420245:LBRM 32 0720
gene id: 420245:LBRM_32_0720
uniprot id: A0A3P3ZE99
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

420245:LBRM 15 0930
gene id: 420245:LBRM_15_0930
uniprot id: A0A3P3Z1W2
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 28 0340
gene id: 420245:LBRM_28_0340
uniprot id: A0A3P3ZAS4
names: Similarity
messages: Belongs to the RNR ribonuclease family.

420245:LBRM 33 0130
gene id: 420245:LBRM_33_0130
uniprot id: A0A3P3ZF93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body

420245:LBRM 29 0660
gene id: 420245:LBRM_29_0660
uniprot id: A0A3P3ZBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

420245:LBRM 29 0150
gene id: 420245:LBRM_29_0150
uniprot id: A0A3P3ZBD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

420245:LBRM 25 1910
gene id: 420245:LBRM_25_1910
uniprot id: A0A3P3Z8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 30 3230
gene id: 420245:LBRM_30_3230
uniprot id: A0A3P3ZAT1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

420245:LBRM 35 6430
gene id: 420245:LBRM_35_6430
uniprot id: A0A3P3ZK03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

420245:LBRM 09 0060
gene id: 420245:LBRM_09_0060
uniprot id: A0A3P3YZ59
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

420245:LBRM 26 1640
gene id: 420245:LBRM_26_1640
uniprot id: A0A3P3Z9A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

420245:LBRM 21 1240
gene id: 420245:LBRM_21_1240
uniprot id: A0A3P3Z676
names: Similarity
messages: Belongs to the tubulin family.

420245:LBRM 25 1300
gene id: 420245:LBRM_25_1300
uniprot id: A0A3P3Z8P0
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 13 1480
gene id: 420245:LBRM_13_1480
uniprot id: A0A3P3Z170
names: Function
names: Similarity
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.

420245:LBRM 14 1180
gene id: 420245:LBRM_14_1180
uniprot id: A0A3P3Z4L2
names: Similarity
messages: Belongs to the TPPP family.

420245:LBRM 07 0570
gene id: 420245:LBRM_07_0570
uniprot id: A0A3P3YYJ0
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

420245:LBRM 07 0050
gene id: 420245:LBRM_07_0050
uniprot id: A0A3P3YYC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.
messages: coated pit

420245:LBRM 33 0760
gene id: 420245:LBRM_33_0760
uniprot id: A0A3P3ZFF8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

420245:LBRM 34 4810
gene id: 420245:LBRM_34_4810
uniprot id: A0A3P3ZHS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.

420245:LBRM 35 4260
gene id: 420245:LBRM_35_4260
uniprot id: A0A3P3ZJ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR1 family.
messages: Golgi apparatus membrane
messages: Membrane

420245:LBRM 29 0990
gene id: 420245:LBRM_29_0990
uniprot id: A0A3P3ZBK2
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

420245:LBRM 34 3050
gene id: 420245:LBRM_34_3050
uniprot id: A0A3P3ZH51
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

420245:LBRM 35 3250
gene id: 420245:LBRM_35_3250
uniprot id: A0A3P3ZIW7
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

420245:LBRM 13 0390
gene id: 420245:LBRM_13_0390
uniprot id: A0A3P3Z148
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

420245:LBRM 18 1410
gene id: 420245:LBRM_18_1410
uniprot id: A0A3P3Z3H9
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

420245:LBRM 27 1370
gene id: 420245:LBRM_27_1370
uniprot id: A0A3P3Z9X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

420245:LBRM 24 1340
gene id: 420245:LBRM_24_1340
uniprot id: A0A3P3Z844
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

420245:LBRM 30 2890
gene id: 420245:LBRM_30_2890
uniprot id: A0A3P3ZD16
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 13 1430
gene id: 420245:LBRM_13_1430
uniprot id: A0A3P3Z163
names: Similarity
messages: Belongs to the PPP phosphatase family.

420245:LBRM 28 2580
gene id: 420245:LBRM_28_2580
uniprot id: A0A3P3ZBB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

420245:LBRM 26 0630
gene id: 420245:LBRM_26_0630
uniprot id: A0A3P3Z948
names: Similarity
messages: Belongs to the GroES chaperonin family.

420245:LBRM 33 2210
gene id: 420245:LBRM_33_2210
uniprot id: A0A3P3ZFV1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

420245:LBRM 30 3620
gene id: 420245:LBRM_30_3620
uniprot id: A0A3P3ZD70
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

420245:LBRM 30 0750
gene id: 420245:LBRM_30_0750
uniprot id: A0A3P3ZCK4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

420245:LBRM 22 0540
gene id: 420245:LBRM_22_0540
uniprot id: A0A3P3Z6M8
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

420245:LBRM 15 1470
gene id: 420245:LBRM_15_1470
uniprot id: A0A3P3Z209
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

420245:LBRM 07 0380
gene id: 420245:LBRM_07_0380
uniprot id: A0A3P3YYF4
names: Similarity
messages: Belongs to the SDHAF4 family.

420245:LBRM 10 0590
gene id: 420245:LBRM_10_0590
uniprot id: A0A3P3YZS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.
messages: Has an integral role during the infection of macrophages in the mammalian host.

420245:LBRM 07 0660
gene id: 420245:LBRM_07_0660
uniprot id: A0A3P3YYJ8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

420245:LBRM 19 1890
gene id: 420245:LBRM_19_1890
uniprot id: A0A3P3Z423
names: Similarity
messages: Belongs to the ATG8 family.

420245:LBRM 23 0320
gene id: 420245:LBRM_23_0320
uniprot id: A0A3P3Z701
names: Similarity
messages: Belongs to the HUS1 family.

420245:LBRM 26 1850
gene id: 420245:LBRM_26_1850
uniprot id: A0A3P3Z9P4
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 34 1220
gene id: 420245:LBRM_34_1220
uniprot id: A0A3P3ZGL6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

420245:LBRM 29 0210
gene id: 420245:LBRM_29_0210
uniprot id: A0A3P3ZBC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

420245:LBRM 35 1880
gene id: 420245:LBRM_35_1880
uniprot id: A0A3P3ZIA6
names: Similarity
messages: Belongs to the peptidase M76 family.

420245:LBRM 17 1030
gene id: 420245:LBRM_17_1030
uniprot id: A0A3P3Z2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

420245:LBRM 35 0660
gene id: 420245:LBRM_35_0660
uniprot id: A0A3P3ZHZ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 16 1370
gene id: 420245:LBRM_16_1370
uniprot id: A0A3P3Z2G4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

420245:LBRM 08 0710
gene id: 420245:LBRM_08_0710
uniprot id: A0A3P3YZ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

420245:LBRM 29 2510
gene id: 420245:LBRM_29_2510
uniprot id: A0A3P3ZC35
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

420245:LBRM 06 0350
gene id: 420245:LBRM_06_0350
uniprot id: A0A3P3YY19
names: Similarity
messages: Belongs to the glutamine synthetase family.

420245:LBRM 29 1610
gene id: 420245:LBRM_29_1610
uniprot id: A0A3P3ZBT4
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 30 0700
gene id: 420245:LBRM_30_0700
uniprot id: A0A3P3ZCD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

420245:LBRM 15 0010
gene id: 420245:LBRM_15_0010
uniprot id: A0A3P3ZHT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 11 0050
gene id: 420245:LBRM_11_0050
uniprot id: A0A3P3Z037
names: Similarity
messages: Belongs to the OPA3 family.

420245:LBRM 18 0690
gene id: 420245:LBRM_18_0690
uniprot id: A0A3P3Z383
names: Similarity
messages: Belongs to the AAA ATPase family.

420245:LBRM 25 1400
gene id: 420245:LBRM_25_1400
uniprot id: A0A3P3Z8U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

420245:LBRM 27 1920
gene id: 420245:LBRM_27_1920
uniprot id: A0A3P3ZA38
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

420245:LBRM 34 3920
gene id: 420245:LBRM_34_3920
uniprot id: A0A3P3ZHX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane

420245:LBRM 18 0870
gene id: 420245:LBRM_18_0870
uniprot id: A0A3P3Z3B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Nucleus

420245:LBRM 05 0190
gene id: 420245:LBRM_05_0190
uniprot id: A0A3P3YXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

420245:LBRM 33 0300
gene id: 420245:LBRM_33_0300
uniprot id: A0A3P3ZFR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

420245:LBRM 05 0670
gene id: 420245:LBRM_05_0670
uniprot id: A0A3P3YXU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

420245:LBRM 35 3720
gene id: 420245:LBRM_35_3720
uniprot id: A0A3P3ZIV8
names: Similarity
messages: Belongs to the CFAP298 family.

420245:LBRM 33 3420
gene id: 420245:LBRM_33_3420
uniprot id: A0A3P3ZG86
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

420245:LBRM 11 0670
gene id: 420245:LBRM_11_0670
uniprot id: A0A3P3Z0I1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 28 2010
gene id: 420245:LBRM_28_2010
uniprot id: A0A3P3ZAX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Cytoplasm

420245:LBRM 33 2140
gene id: 420245:LBRM_33_2140
uniprot id: A0A3P3ZGJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

420245:LBRM 19 0140
gene id: 420245:LBRM_19_0140
uniprot id: A0A3P3Z024
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 25 1660
gene id: 420245:LBRM_25_1660
uniprot id: A0A3P3Z8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal TPase family.
messages: Nucleus

420245:LBRM 05 1190
gene id: 420245:LBRM_05_1190
uniprot id: A0A3P3YY59
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

420245:LBRM 35 1000
gene id: 420245:LBRM_35_1000
uniprot id: A0A3P3ZI21
names: Similarity
messages: Belongs to the NifU family.

420245:LBRM 04 0440
gene id: 420245:LBRM_04_0440
uniprot id: A0A3P3YXI9
names: Similarity
messages: Belongs to the APC10 family.

420245:LBRM 15 1010
gene id: 420245:LBRM_15_1010
uniprot id: A0A3P3Z1W7
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.

420245:LBRM 28 2990
gene id: 420245:LBRM_28_2990
uniprot id: A0A3P3ZB76
names: Similarity
messages: Belongs to the heat shock protein 70 family.

420245:LBRM 16 1400
gene id: 420245:LBRM_16_1400
uniprot id: A0A3P3Z2Q6
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.

420245:LBRM 35 4430
gene id: 420245:LBRM_35_4430
uniprot id: A0A3P3ZJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 31 1450
gene id: 420245:LBRM_31_1450
uniprot id: A0A3P3ZDJ2
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 35 3320
gene id: 420245:LBRM_35_3320
uniprot id: A0A3P3ZJ35
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

420245:LBRM 19 1100
gene id: 420245:LBRM_19_1100
uniprot id: A0A3P3Z426
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Cytoplasm

420245:LBRM 25 0980
gene id: 420245:LBRM_25_0980
uniprot id: A0A3P3Z8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

420245:LBRM 33 2610
gene id: 420245:LBRM_33_2610
uniprot id: A0A3P3ZG14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

420245:LBRM 32 3090
gene id: 420245:LBRM_32_3090
uniprot id: A0A3P3ZEW0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Dynein axonemal particle
messages: neuron projection

420245:LBRM 18 0230
gene id: 420245:LBRM_18_0230
uniprot id: A0A3P3Z340
names: Similarity
messages: Belongs to the AHA1 family.

420245:LBRM 07 0100
gene id: 420245:LBRM_07_0100
uniprot id: A0A3P3YYD3
names: Similarity
messages: Belongs to the peptidase M16 family.

420245:LBRM 30 1550
gene id: 420245:LBRM_30_1550
uniprot id: A0A3P3ZCJ7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 26 1490
gene id: 420245:LBRM_26_1490
uniprot id: A0A3P3Z983
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

420245:LBRM 11 0710
gene id: 420245:LBRM_11_0710
uniprot id: A0A3P3Z080
names: Similarity
messages: Belongs to the AAA ATPase family.

420245:LBRM 35 3630
gene id: 420245:LBRM_35_3630
uniprot id: A0A3P3ZIU3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

420245:LBRM 29 2340
gene id: 420245:LBRM_29_2340
uniprot id: A0A3P3ZC08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

420245:LBRM 34 2420
gene id: 420245:LBRM_34_2420
uniprot id: A0A3P3ZGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: nucleolus
messages: nucleoplasm

420245:LBRM 06 1050
gene id: 420245:LBRM_06_1050
uniprot id: A0A3P3YYA3
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

420245:LBRM 35 5510
gene id: 420245:LBRM_35_5510
uniprot id: A0A3P3ZJD3
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

420245:LBRM 28 0460
gene id: 420245:LBRM_28_0460
uniprot id: A0A3P3ZAS7
names: Similarity
messages: Belongs to the RNR ribonuclease family.

420245:LBRM 18 1060
gene id: 420245:LBRM_18_1060
uniprot id: A0A3P3Z3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 32 1050
gene id: 420245:LBRM_32_1050
uniprot id: A0A3P3ZEG4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

420245:LBRM 34 1000
gene id: 420245:LBRM_34_1000
uniprot id: A0A3P3ZGK7
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 13 0050
gene id: 420245:LBRM_13_0050
uniprot id: A0A3P3Z0N8
names: Caution
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 10 0030
gene id: 420245:LBRM_10_0030
uniprot id: A0A3P3YZF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

420245:LBRM 34 1610
gene id: 420245:LBRM_34_1610
uniprot id: A0A3P3ZGT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

420245:LBRM 31 2680
gene id: 420245:LBRM_31_2680
uniprot id: A0A3P3ZE21
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 30 0410
gene id: 420245:LBRM_30_0410
uniprot id: A0A3P3ZCB7
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

420245:LBRM 34 1680
gene id: 420245:LBRM_34_1680
uniprot id: A0A3P3ZGS6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

420245:LBRM 05 0360
gene id: 420245:LBRM_05_0360
uniprot id: A0A3P3YXP0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G.

420245:LBRM 32 1170
gene id: 420245:LBRM_32_1170
uniprot id: A0A3P3ZES3
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

420245:LBRM 35 3650
gene id: 420245:LBRM_35_3650
uniprot id: A0A3P3ZJA1
names: Similarity
messages: Belongs to the VPS26 family.

420245:LBRM 11 0550
gene id: 420245:LBRM_11_0550
uniprot id: A0A3P3Z0H3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS21 family.

420245:LBRM 04 0350
gene id: 420245:LBRM_04_0350
uniprot id: A0A3P3YXB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

420245:LBRM 27 0510
gene id: 420245:LBRM_27_0510
uniprot id: A0A3P3Z9N7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

420245:LBRM 09 1080
gene id: 420245:LBRM_09_1080
uniprot id: A0A3P3YZG4
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

420245:LBRM 30 3550
gene id: 420245:LBRM_30_3550
uniprot id: A0A3P3ZDS9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

420245:LBRM 30 3000
gene id: 420245:LBRM_30_3000
uniprot id: A0A3P3ZD03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

420245:LBRM 24 1460
gene id: 420245:LBRM_24_1460
uniprot id: A0A3P3Z810
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

420245:LBRM 24 0690
gene id: 420245:LBRM_24_0690
uniprot id: A0A3P3Z7V4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

420245:LBRM 09 0070
gene id: 420245:LBRM_09_0070
uniprot id: A0A3P3YYZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Mitochondrion
messages: Nucleus

420245:LBRM 34 4100
gene id: 420245:LBRM_34_4100
uniprot id: A0A3P3ZHF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

420245:LBRM 35 3480
gene id: 420245:LBRM_35_3480
uniprot id: A0A3P3ZIS8
names: Similarity
messages: Belongs to the CCZ1 family.

420245:LBRM 19 0710
gene id: 420245:LBRM_19_0710
uniprot id: A0A3P3ZG86
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

420245:LBRM 33 3330
gene id: 420245:LBRM_33_3330
uniprot id: A0A3P3ZG76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

420245:LBRM 07 0390
gene id: 420245:LBRM_07_0390
uniprot id: A0A3P3YYG0
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 15 0120
gene id: 420245:LBRM_15_0120
uniprot id: A0A3P3Z1N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 35 3300
gene id: 420245:LBRM_35_3300
uniprot id: A0A3P3ZJ58
names: Similarity
messages: Belongs to the LipB family.

420245:LBRM 30 1060
gene id: 420245:LBRM_30_1060
uniprot id: A0A3P3ZCN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

420245:LBRM 25 0600
gene id: 420245:LBRM_25_0600
uniprot id: A0A3P3Z8A2
names: Function
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

420245:LBRM 21 1270
gene id: 420245:LBRM_21_1270
uniprot id: A0A3P3Z667
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 25 1710
gene id: 420245:LBRM_25_1710
uniprot id: A0A3P3Z8W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

420245:LBRM 15 0550
gene id: 420245:LBRM_15_0550
uniprot id: A0A3P3Z1V6
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

420245:LBRM 26 0980
gene id: 420245:LBRM_26_0980
uniprot id: A0A3P3Z929
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

420245:LBRM 09 1490
gene id: 420245:LBRM_09_1490
uniprot id: A0A3P3YZK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

420245:LBRM 29 1180
gene id: 420245:LBRM_29_1180
uniprot id: A0A3P3ZBM6
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

420245:LBRM 34 2850
gene id: 420245:LBRM_34_2850
uniprot id: A0A3P3ZHN4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues.

420245:LBRM 26 1840
gene id: 420245:LBRM_26_1840
uniprot id: A0A3P3Z9B8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

420245:LBRM 28 2770
gene id: 420245:LBRM_28_2770
uniprot id: A0A3P3ZBI3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

420245:LBRM 28 2330
gene id: 420245:LBRM_28_2330
uniprot id: A0A3P3ZAZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

420245:LBRM 29 1600
gene id: 420245:LBRM_29_1600
uniprot id: A0A3P3ZBR8
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 16 1090
gene id: 420245:LBRM_16_1090
uniprot id: A0A3P3Z2E1
names: Function
names: Similarity
messages: Belongs to the UFM1 family.
messages: Ubiquitin-like modifier.

420245:LBRM 25 1440
gene id: 420245:LBRM_25_1440
uniprot id: A0A3P3Z925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

420245:LBRM 35 2710
gene id: 420245:LBRM_35_2710
uniprot id: A0A3P3ZIJ8
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 26 2120
gene id: 420245:LBRM_26_2120
uniprot id: A0A3P3Z9K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

420245:LBRM 30 3590
gene id: 420245:LBRM_30_3590
uniprot id: A0A3P3ZDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

420245:LBRM 01 0380
gene id: 420245:LBRM_01_0380
uniprot id: A0A3P3YWI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

420245:LBRM 13 0340
gene id: 420245:LBRM_13_0340
uniprot id: A0A3P3Z0T4
names: Similarity
messages: Belongs to the CCDC124 family.

420245:LBRM 29 1150
gene id: 420245:LBRM_29_1150
uniprot id: A0A3P3ZBM6
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

420245:LBRM 34 0990
gene id: 420245:LBRM_34_0990
uniprot id: A0A3P3ZGY0
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 29 2140
gene id: 420245:LBRM_29_2140
uniprot id: A0A3P3ZC70
names: Similarity
messages: Belongs to the Rab GDI family.

420245:LBRM 21 0610
gene id: 420245:LBRM_21_0610
uniprot id: A0A3P3Z6A5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

420245:LBRM 22 0510
gene id: 420245:LBRM_22_0510
uniprot id: A0A3P3Z6U7
names: Similarity
messages: Belongs to the AAA ATPase family.

420245:LBRM 34 2610
gene id: 420245:LBRM_34_2610
uniprot id: A0A3P3ZH31
names: Similarity
messages: Belongs to the syntaxin family.

420245:LBRM 30 0240
gene id: 420245:LBRM_30_0240
uniprot id: A0A3P3ZC91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 04 1140
gene id: 420245:LBRM_04_1140
uniprot id: A0A3P3YXI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

420245:LBRM 28 1290
gene id: 420245:LBRM_28_1290
uniprot id: A0A3P3ZAQ2
names: Similarity
messages: Belongs to the copine family.

420245:LBRM 18 1650
gene id: 420245:LBRM_18_1650
uniprot id: A0A3P3Z3S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

420245:LBRM 04 0740
gene id: 420245:LBRM_04_0740
uniprot id: A0A3P3YXH2
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

420245:LBRM 07 0310
gene id: 420245:LBRM_07_0310
uniprot id: A0A3P3YYF0
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 34 3850
gene id: 420245:LBRM_34_3850
uniprot id: A0A3P3ZHI4
names: Subcellular Location Annotation
messages: cilium axoneme

420245:LBRM 32 0780
gene id: 420245:LBRM_32_0780
uniprot id: A0A3P3ZEN8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

420245:LBRM 05 0720
gene id: 420245:LBRM_05_0720
uniprot id: A0A3P3YXS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

420245:LBRM 34 1570
gene id: 420245:LBRM_34_1570
uniprot id: A0A3P3ZGR4
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

420245:LBRM 08 0780
gene id: 420245:LBRM_08_0780
uniprot id: A0A3P3YYY5
names: Similarity
messages: Belongs to the dpy-30 family.

420245:LBRM 11 0430
gene id: 420245:LBRM_11_0430
uniprot id: A0A3P3Z063
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 31 3080
gene id: 420245:LBRM_31_3080
uniprot id: A0A3P3ZE48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

420245:LBRM 32 4070
gene id: 420245:LBRM_32_4070
uniprot id: A0A3P3ZFH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

420245:LBRM 10 0750
gene id: 420245:LBRM_10_0750
uniprot id: A0A3P3YZV8
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

420245:LBRM 27 2560
gene id: 420245:LBRM_27_2560
uniprot id: A0A3P3ZAF0
names: Similarity
messages: Belongs to the synaptobrevin family.

420245:LBRM 26 1500
gene id: 420245:LBRM_26_1500
uniprot id: A0A3P3Z990
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

420245:LBRM 30 1180
gene id: 420245:LBRM_30_1180
uniprot id: A0A3P3ZCJ0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

420245:LBRM 35 1100
gene id: 420245:LBRM_35_1100
uniprot id: A0A3P3ZIA3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

420245:LBRM 28 0120
gene id: 420245:LBRM_28_0120
uniprot id: A0A3P3ZAP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

420245:LBRM 33 0960
gene id: 420245:LBRM_33_0960
uniprot id: A0A3P3ZG23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

420245:LBRM 10 0310
gene id: 420245:LBRM_10_0310
uniprot id: A0A3P3YZJ2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

420245:LBRM 24 1780
gene id: 420245:LBRM_24_1780
uniprot id: A0A3P3Z866
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

420245:LBRM 27 1450
gene id: 420245:LBRM_27_1450
uniprot id: A0A3P3ZA60
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

420245:LBRM 29 0960
gene id: 420245:LBRM_29_0960
uniprot id: A0A3P3ZBT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

420245:LBRM 35 0940
gene id: 420245:LBRM_35_0940
uniprot id: A0A3P3ZI14
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

420245:LBRM 35 0400
gene id: 420245:LBRM_35_0400
uniprot id: A0A3P3ZHV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

420245:LBRM 09 0940
gene id: 420245:LBRM_09_0940
uniprot id: A0A3P3YZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

420245:LBRM 28 2270
gene id: 420245:LBRM_28_2270
uniprot id: A0A3P3ZB44
names: Similarity
messages: Belongs to the DEAD box helicase family.

420245:LBRM 34 3250
gene id: 420245:LBRM_34_3250
uniprot id: A0A3P3ZH83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

420245:LBRM 35 3400
gene id: 420245:LBRM_35_3400
uniprot id: A0A3P3ZJ44
names: Function
messages: Could act as a receptor for an unknown ligand.

420245:LBRM 18 1140
gene id: 420245:LBRM_18_1140
uniprot id: A0A3P3Z3I3
names: Similarity
messages: Belongs to the cytidylyltransferase family.

420245:LBRM 33 3470
gene id: 420245:LBRM_33_3470
uniprot id: A0A3P3ZG73
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 18 0760
gene id: 420245:LBRM_18_0760
uniprot id: A0A3P3Z384
names: Similarity
messages: Belongs to the citrate synthase family.

420245:LBRM 34 2990
gene id: 420245:LBRM_34_2990
uniprot id: A0A3P3ZHH4
names: Similarity
messages: Belongs to the FGGY kinase family.

420245:LBRM 35 2030
gene id: 420245:LBRM_35_2030
uniprot id: A0A3P3ZIC7
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

420245:LBRM 33 3100
gene id: 420245:LBRM_33_3100
uniprot id: A0A3P3ZG56
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 14 0970
gene id: 420245:LBRM_14_0970
uniprot id: A0A3P3Z1I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Membrane
messages: Monomer.

420245:LBRM 22 0500
gene id: 420245:LBRM_22_0500
uniprot id: A0A3P3Z6L9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 35 4900
gene id: 420245:LBRM_35_4900
uniprot id: A0A3P3ZJJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

420245:LBRM 21 0900
gene id: 420245:LBRM_21_0900
uniprot id: A0A3P3Z633
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

420245:LBRM 28 0560
gene id: 420245:LBRM_28_0560
uniprot id: A0A3P3ZAT1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

420245:LBRM 19 1320
gene id: 420245:LBRM_19_1320
uniprot id: A0A3P3Z3V2
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

420245:LBRM 13 1450
gene id: 420245:LBRM_13_1450
uniprot id: A0A3P3Z137
names: Similarity
messages: Belongs to the TCP10 family.

420245:LBRM 34 1630
gene id: 420245:LBRM_34_1630
uniprot id: A0A3P3ZHC8
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 34 4850
gene id: 420245:LBRM_34_4850
uniprot id: A0A3P3ZHM0
names: Similarity
messages: Belongs to the RecA family. DMC1 subfamily.

420245:LBRM 16 0480
gene id: 420245:LBRM_16_0480
uniprot id: A0A3P3Z2A6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

420245:LBRM 26 2160
gene id: 420245:LBRM_26_2160
uniprot id: A0A3P3Z9F8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 05 1060
gene id: 420245:LBRM_05_1060
uniprot id: A0A3P3YXW5
names: Similarity
messages: Belongs to the AFG1 ATPase family.

420245:LBRM 35 5200
gene id: 420245:LBRM_35_5200
uniprot id: A0A3P3ZJP7
names: Similarity
messages: Belongs to the alkB family.

420245:LBRM 34 1350
gene id: 420245:LBRM_34_1350
uniprot id: A0A3P3ZH28
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

420245:LBRM 14 1540
gene id: 420245:LBRM_14_1540
uniprot id: A0A3P3Z1L3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

420245:LBRM 34 3820
gene id: 420245:LBRM_34_3820
uniprot id: A0A3P3ZHA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

420245:LBRM 35 3990
gene id: 420245:LBRM_35_3990
uniprot id: A0A3P3Z3F9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

420245:LBRM 28 2320
gene id: 420245:LBRM_28_2320
uniprot id: A0A3P3ZB91
names: Similarity
messages: Belongs to the cullin family.

420245:LBRM 35 0740
gene id: 420245:LBRM_35_0740
uniprot id: A0A3P3ZIH9
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.

420245:LBRM 21 0950
gene id: 420245:LBRM_21_0950
uniprot id: A0A3P3Z631
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

420245:LBRM 11 0760
gene id: 420245:LBRM_11_0760
uniprot id: A0A3P3Z0A0
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

420245:LBRM 35 3350
gene id: 420245:LBRM_35_3350
uniprot id: A0A3P3ZIR4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

420245:LBRM 24 0110
gene id: 420245:LBRM_24_0110
uniprot id: A0A3P3Z7I9
names: Function
names: Subcellular Location Annotation
messages: Displays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities. Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation. At the mRNAs 5' end, methylates the ribose 2' OH group of the first transcribed nucleotide, thereby producing a 2'-O-methylpurine cap. At the 3' end, functions as a processivity factor which stimulates the activity of the viral poly(A) polymerase OPG063 that creates mRNA's poly(A) tail. In the presence of OPG102, OPG063 does not dissociate from the RNA allowing tail elongation to around 250 adenylates.
messages: Virion

420245:LBRM 30 3160
gene id: 420245:LBRM_30_3160
uniprot id: A0A3P3ZD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus

420245:LBRM 14 0310
gene id: 420245:LBRM_14_0310
uniprot id: A0A3P3Z1B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.

420245:LBRM 32 2880
gene id: 420245:LBRM_32_2880
uniprot id: A0A3P3ZF46
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

420245:LBRM 27 2690
gene id: 420245:LBRM_27_2690
uniprot id: A0A3P3ZAA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

420245:LBRM 32 3520
gene id: 420245:LBRM_32_3520
uniprot id: A0A3P3ZF02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: Cytoplasm

420245:LBRM 32 1760
gene id: 420245:LBRM_32_1760
uniprot id: A0A3P3ZEJ2
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: Monomer.

420245:LBRM 11 1020
gene id: 420245:LBRM_11_1020
uniprot id: A0A3P3Z0C6
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 22 1180
gene id: 420245:LBRM_22_1180
uniprot id: A0A3P3Z6S6
names: Similarity
messages: Belongs to the ATG8 family.

420245:LBRM 16 1220
gene id: 420245:LBRM_16_1220
uniprot id: A0A3P3Z2F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

420245:LBRM 18 1430
gene id: 420245:LBRM_18_1430
uniprot id: A0A3P3Z3H1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

420245:LBRM 35 5190
gene id: 420245:LBRM_35_5190
uniprot id: A0A3P3ZJH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

420245:LBRM 09 0990
gene id: 420245:LBRM_09_0990
uniprot id: A0A3P3YZ96
names: Similarity
messages: Belongs to the NEMF family.

420245:LBRM 35 2980
gene id: 420245:LBRM_35_2980
uniprot id: A0A3P3ZIU0
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 21 1160
gene id: 420245:LBRM_21_1160
uniprot id: A0A3P3Z661
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 17 0080
gene id: 420245:LBRM_17_0080
uniprot id: A0A3P3Z2L6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

420245:LBRM 35 3620
gene id: 420245:LBRM_35_3620
uniprot id: A0A3P3ZIU3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

420245:LBRM 30 2530
gene id: 420245:LBRM_30_2530
uniprot id: A0A3P3ZCW6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 34 3830
gene id: 420245:LBRM_34_3830
uniprot id: A0A3P3ZHQ6
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

420245:LBRM 11 0800
gene id: 420245:LBRM_11_0800
uniprot id: A0A3P3Z0A7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

420245:LBRM 15 0840
gene id: 420245:LBRM_15_0840
uniprot id: A0A3P3Z1Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

420245:LBRM 19 1140
gene id: 420245:LBRM_19_1140
uniprot id: A0A3P3Z3U9
names: Similarity
messages: Belongs to the ATG8 family.

420245:LBRM 10 0170
gene id: 420245:LBRM_10_0170
uniprot id: A0A3P3YZL4
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

420245:LBRM 19 1120
gene id: 420245:LBRM_19_1120
uniprot id: A0A3P3Z3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

420245:LBRM 34 0370
gene id: 420245:LBRM_34_0370
uniprot id: A0A3P3ZGF0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

420245:LBRM 32 2780
gene id: 420245:LBRM_32_2780
uniprot id: A0A3P3ZF37
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

420245:LBRM 21 1290
gene id: 420245:LBRM_21_1290
uniprot id: A0A3P3Z6H1
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

420245:LBRM 16 0250
gene id: 420245:LBRM_16_0250
uniprot id: A0A3P3Z289
names: Similarity
messages: Belongs to the ELP3 family.

420245:LBRM 32 3780
gene id: 420245:LBRM_32_3780
uniprot id: A0A3P3ZF31
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

420245:LBRM 05 0350
gene id: 420245:LBRM_05_0350
uniprot id: A0A3P3YXN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Trypanothione is the parasite analog of glutathione; this enzyme is the equivalent of glutathione reductase.

420245:LBRM 34 4710
gene id: 420245:LBRM_34_4710
uniprot id: A0A3P3ZHK0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

420245:LBRM 26 2660
gene id: 420245:LBRM_26_2660
uniprot id: A0A3P3Z9R0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

420245:LBRM 29 0770
gene id: 420245:LBRM_29_0770
uniprot id: A0A3P3ZBR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: nucleolus

420245:LBRM 17 0690
gene id: 420245:LBRM_17_0690
uniprot id: A0A3P3Z333
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

420245:LBRM 35 0720
gene id: 420245:LBRM_35_0720
uniprot id: A0A3P3ZHZ1
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

420245:LBRM 06 1250
gene id: 420245:LBRM_06_1250
uniprot id: A0A3P3YYL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

420245:LBRM 34 2790
gene id: 420245:LBRM_34_2790
uniprot id: A0A3P3ZHF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

420245:LBRM 30 3340
gene id: 420245:LBRM_30_3340
uniprot id: A0A3P3ZD26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

420245:LBRM 26 0900
gene id: 420245:LBRM_26_0900
uniprot id: A0A3P3Z952
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

420245:LBRM 25 0080
gene id: 420245:LBRM_25_0080
uniprot id: A0A3P3Z882
names: Similarity
messages: Belongs to the polyadenylate-binding protein type-1 family.

420245:LBRM 21 1810
gene id: 420245:LBRM_21_1810
uniprot id: A0A3P3Z6B0
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

420245:LBRM 09 1120
gene id: 420245:LBRM_09_1120
uniprot id: A0A3P3YZG7
names: Similarity
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.

420245:LBRM 31 0010
gene id: 420245:LBRM_31_0010
uniprot id: A0A3P3ZD72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

420245:LBRM 16 0920
gene id: 420245:LBRM_16_0920
uniprot id: A0A3P3Z2L9
names: Function
names: Similarity
messages: Belongs to the calflagin family.
messages: May contribute to the rapid motility of the trypanosomes, playing a role either in flagellar structure or in calcium metabolism. Could alternate between a GDP-bound inactive form to a calcium/GTP-bound active form.

420245:LBRM 29 0250
gene id: 420245:LBRM_29_0250
uniprot id: A0A3P3ZBE6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

420245:LBRM 12 0680
gene id: 420245:LBRM_12_0680
uniprot id: A0A3P3Z0U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: centriolar satellite
messages: cilium membrane

420245:LBRM 28 2030
gene id: 420245:LBRM_28_2030
uniprot id: A0A3P3ZBA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP96 family.
messages: centrosome

420245:LBRM 30 0960
gene id: 420245:LBRM_30_0960
uniprot id: A0A3P3ZCM4
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

420245:LBRM 34 2940
gene id: 420245:LBRM_34_2940
uniprot id: A0A3P3ZH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 30 2020
gene id: 420245:LBRM_30_2020
uniprot id: A0A3P3ZCR6
names: Similarity
messages: Belongs to the CCDC25 family.

420245:LBRM 33 3020
gene id: 420245:LBRM_33_3020
uniprot id: A0A3P3ZGI9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

420245:LBRM 01 0430
gene id: 420245:LBRM_01_0430
uniprot id: A0A3P3YWP4
names: Similarity
messages: Belongs to the dymeclin family.

420245:LBRM 24 2130
gene id: 420245:LBRM_24_2130
uniprot id: A0A3P3ZGY1
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

420245:LBRM 07 0490
gene id: 420245:LBRM_07_0490
uniprot id: A0A3P3YYH0
names: Subcellular Location Annotation
messages: nucleolus

420245:LBRM 35 3500
gene id: 420245:LBRM_35_3500
uniprot id: A0A3P3ZIT3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

420245:LBRM 27 0870
gene id: 420245:LBRM_27_0870
uniprot id: A0A3P3Z9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

420245:LBRM 17 1550
gene id: 420245:LBRM_17_1550
uniprot id: A0A3P3Z3B6
names: Similarity
messages: Belongs to the ZPR1 family.

420245:LBRM 32 4110
gene id: 420245:LBRM_32_4110
uniprot id: A0A3P3ZF78
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

420245:LBRM 35 4770
gene id: 420245:LBRM_35_4770
uniprot id: A0A3P3ZJI3
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

420245:LBRM 17 1530
gene id: 420245:LBRM_17_1530
uniprot id: A0A3P3Z314
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

420245:LBRM 25 1530
gene id: 420245:LBRM_25_1530
uniprot id: A0A3P3Z8N0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 16 0620
gene id: 420245:LBRM_16_0620
uniprot id: A0A3P3Z268
names: Similarity
messages: Belongs to the TOP6A family.

420245:LBRM 32 1200
gene id: 420245:LBRM_32_1200
uniprot id: A0A3P3ZEE2
names: Similarity
messages: Belongs to the exportin family.

420245:LBRM 32 3970
gene id: 420245:LBRM_32_3970
uniprot id: A0A3P3ZFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane

420245:LBRM 30 3510
gene id: 420245:LBRM_30_3510
uniprot id: A0A3P3ZD63
names: Similarity
messages: Belongs to the yippee family.

420245:LBRM 29 2270
gene id: 420245:LBRM_29_2270
uniprot id: A0A3P3ZC15
names: Similarity
messages: Belongs to the peptidase C19 family.

420245:LBRM 15 1450
gene id: 420245:LBRM_15_1450
uniprot id: A0A3P3Z206
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

420245:LBRM 28 3140
gene id: 420245:LBRM_28_3140
uniprot id: A0A3P3ZB84
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 31 3610
gene id: 420245:LBRM_31_3610
uniprot id: A0A3P3ZEH8
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 30 0220
gene id: 420245:LBRM_30_0220
uniprot id: A0A3P3ZCA0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 31 0140
gene id: 420245:LBRM_31_0140
uniprot id: A0A3P3ZDA2
names: Similarity
messages: Belongs to the peptidase C19 family.

420245:LBRM 34 1140
gene id: 420245:LBRM_34_1140
uniprot id: A0A3P3ZH08
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

420245:LBRM 34 2630
gene id: 420245:LBRM_34_2630
uniprot id: A0A3P3ZHL4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

420245:LBRM 28 0410
gene id: 420245:LBRM_28_0410
uniprot id: A0A3P3ZAJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton

420245:LBRM 34 0440
gene id: 420245:LBRM_34_0440
uniprot id: A0A3P3ZGC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

420245:LBRM 05 0130
gene id: 420245:LBRM_05_0130
uniprot id: A0A3P3YXT4
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 05 0180
gene id: 420245:LBRM_05_0180
uniprot id: A0A3P3YXL7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

420245:LBRM 35 4010
gene id: 420245:LBRM_35_4010
uniprot id: A0A3P3ZIY6
names: Similarity
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Part of the nascent polypeptide-associated complex (NAC).

420245:LBRM 22 0800
gene id: 420245:LBRM_22_0800
uniprot id: A0A3P3Z6P3
names: Similarity
messages: Belongs to the PRP18 family.

420245:LBRM 27 0630
gene id: 420245:LBRM_27_0630
uniprot id: A0A3P3ZA23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flagellar radial spoke RSP3 family.
messages: flagellum axoneme

420245:LBRM 08 0950
gene id: 420245:LBRM_08_0950
uniprot id: A0A3P3YZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

420245:LBRM 01 0470
gene id: 420245:LBRM_01_0470
uniprot id: A0A3P3YWJ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

420245:LBRM 30 0820
gene id: 420245:LBRM_30_0820
uniprot id: A0A3P3ZCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

420245:LBRM 08 0320
gene id: 420245:LBRM_08_0320
uniprot id: A0A3P3YYR2
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

420245:LBRM 35 2890
gene id: 420245:LBRM_35_2890
uniprot id: A0A3P3ZJ41
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 04 1020
gene id: 420245:LBRM_04_1020
uniprot id: A0A3P3YXI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

420245:LBRM 04 0930
gene id: 420245:LBRM_04_0930
uniprot id: A0A3P3YXE0
names: Similarity
messages: Belongs to the TRAPPC13 family.

420245:LBRM 35 5640
gene id: 420245:LBRM_35_5640
uniprot id: A0A3P3ZJE5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

420245:LBRM 34 2120
gene id: 420245:LBRM_34_2120
uniprot id: A0A3P3ZGY5
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

420245:LBRM 07 0780
gene id: 420245:LBRM_07_0780
uniprot id: A0A3P3YYK6
names: Similarity
messages: Belongs to the centrin family.

420245:LBRM 34 2640
gene id: 420245:LBRM_34_2640
uniprot id: A0A3P3ZHJ2
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

420245:LBRM 33 0720
gene id: 420245:LBRM_33_0720
uniprot id: A0A3P3ZFR7
names: Similarity
messages: Belongs to the ERG4/ERG24 family.

420245:LBRM 34 5200
gene id: 420245:LBRM_34_5200
uniprot id: A0A3P3ZHR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

420245:LBRM 34 4310
gene id: 420245:LBRM_34_4310
uniprot id: A0A3P3ZI03
names: Similarity
messages: Belongs to the PIH1 family.

420245:LBRM 29 0080
gene id: 420245:LBRM_29_0080
uniprot id: A0A3P3ZBE7
names: Similarity
messages: Belongs to the syntaxin family.

420245:LBRM 35 4340
gene id: 420245:LBRM_35_4340
uniprot id: A0A3P3ZJF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

420245:LBRM 32 0810
gene id: 420245:LBRM_32_0810
uniprot id: A0A3P3ZEA6
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 19 0980
gene id: 420245:LBRM_19_0980
uniprot id: A0A3P3Z406
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

420245:LBRM 29 0340
gene id: 420245:LBRM_29_0340
uniprot id: A0A3P3ZBJ3
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 31 0050
gene id: 420245:LBRM_31_0050
uniprot id: A0A3P3ZD88
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

420245:LBRM 34 4640
gene id: 420245:LBRM_34_4640
uniprot id: A0A3P3ZI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus

420245:LBRM 35 3710
gene id: 420245:LBRM_35_3710
uniprot id: A0A3P3ZIV4
names: Similarity
messages: Belongs to the SMAP family.

420245:LBRM 23 0330
gene id: 420245:LBRM_23_0330
uniprot id: A0A3P3Z6Z4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

420245:LBRM 32 1000
gene id: 420245:LBRM_32_1000
uniprot id: A0A3P3ZEB9
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated.

420245:LBRM 16 0800
gene id: 420245:LBRM_16_0800
uniprot id: A0A3P3Z2C9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

420245:LBRM 06 1260
gene id: 420245:LBRM_06_1260
uniprot id: A0A3P3YYB4
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

420245:LBRM 30 1370
gene id: 420245:LBRM_30_1370
uniprot id: A0A3P3ZCI4
names: Similarity
messages: Belongs to the pyridoxine kinase family.

420245:LBRM 34 4870
gene id: 420245:LBRM_34_4870
uniprot id: A0A3P3ZI52
names: Similarity
messages: Belongs to the MCM family.

420245:LBRM 25 0060
gene id: 420245:LBRM_25_0060
uniprot id: A0A3P3Z8C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

420245:LBRM 27 1090
gene id: 420245:LBRM_27_1090
uniprot id: A0A3P3Z9W4
names: Similarity
messages: Belongs to the SEC6 family.

420245:LBRM 30 1920
gene id: 420245:LBRM_30_1920
uniprot id: A0A3P3ZDC3
names: Similarity
messages: Belongs to the ZNF277 family.

420245:LBRM 27 0300
gene id: 420245:LBRM_27_0300
uniprot id: A0A3P3Z9W8
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

420245:LBRM 30 0090
gene id: 420245:LBRM_30_0090
uniprot id: A0A3P3ZC85
names: Similarity
messages: Belongs to the cyclin family.

420245:LBRM 35 7260
gene id: 420245:LBRM_35_7260
uniprot id: A0A3P3ZK18
names: Similarity
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.

420245:LBRM 13 0760
gene id: 420245:LBRM_13_0760
uniprot id: A0A3P3Z0Y7
names: Similarity
messages: Belongs to the actin family.

420245:LBRM 18 1630
gene id: 420245:LBRM_18_1630
uniprot id: A0A3P3Z3K1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 27 1210
gene id: 420245:LBRM_27_1210
uniprot id: A0A3P3ZA44
names: Similarity
messages: Belongs to the TSR2 family.

420245:LBRM 34 0140
gene id: 420245:LBRM_34_0140
uniprot id: A0A3P3ZG92
names: Similarity
messages: Belongs to the UQCRB/QCR7 family.

420245:LBRM 27 0390
gene id: 420245:LBRM_27_0390
uniprot id: A0A3P3ZH75
names: Similarity
messages: Belongs to the KRI1 family.

420245:LBRM 15 0690
gene id: 420245:LBRM_15_0690
uniprot id: A0A3P3Z1U0
names: Similarity
messages: Belongs to the CMC family.

420245:LBRM 35 5430
gene id: 420245:LBRM_35_5430
uniprot id: A0A3P3ZJC3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

420245:LBRM 33 1610
gene id: 420245:LBRM_33_1610
uniprot id: A0A3P3ZG42
names: Similarity
messages: Belongs to the syntaxin family.

420245:LBRM 27 2230
gene id: 420245:LBRM_27_2230
uniprot id: A0A3P3ZAH3
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

420245:LBRM 33 1260
gene id: 420245:LBRM_33_1260
uniprot id: A0A3P3ZG12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

420245:LBRM 31 0300
gene id: 420245:LBRM_31_0300
uniprot id: A0A3P3ZDG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

420245:LBRM 15 0850
gene id: 420245:LBRM_15_0850
uniprot id: A0A3P3Z271
names: Similarity
messages: Belongs to the Rab GDI family.

420245:LBRM 11 0180
gene id: 420245:LBRM_11_0180
uniprot id: A0A3P3Z033
names: Similarity
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.

420245:LBRM 34 0030
gene id: 420245:LBRM_34_0030
uniprot id: A0A3P3ZHT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 28 1960
gene id: 420245:LBRM_28_1960
uniprot id: A0A3P3ZAV9
names: Similarity
messages: Belongs to the AAA ATPase family. PCH2 subfamily.

420245:LBRM 31 2010
gene id: 420245:LBRM_31_2010
uniprot id: A0A3P3ZDW0
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 17 0180
gene id: 420245:LBRM_17_0180
uniprot id: A0A3P3Z2Q2
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Belongs to the peptidase M20B family.

420245:LBRM 21 0700
gene id: 420245:LBRM_21_0700
uniprot id: A0A3P3Z614
names: Similarity
messages: Belongs to the phosphohexose mutase family.

420245:LBRM 15 1230
gene id: 420245:LBRM_15_1230
uniprot id: A0A3P3Z213
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

420245:LBRM 34 0250
gene id: 420245:LBRM_34_0250
uniprot id: A0A3P3ZGQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

420245:LBRM 28 2020
gene id: 420245:LBRM_28_2020
uniprot id: A0A3P3ZAX5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 15 0610
gene id: 420245:LBRM_15_0610
uniprot id: A0A3P3Z228
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 19 1070
gene id: 420245:LBRM_19_1070
uniprot id: A0A3P3Z3S9
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 30 0600
gene id: 420245:LBRM_30_0600
uniprot id: A0A3P3ZCC1
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

420245:LBRM 34 1730
gene id: 420245:LBRM_34_1730
uniprot id: A0A3P3ZGR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

420245:LBRM 33 1900
gene id: 420245:LBRM_33_1900
uniprot id: A0A3P3ZFU1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

420245:LBRM 34 0110
gene id: 420245:LBRM_34_0110
uniprot id: A0A3P3ZGB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

420245:LBRM 01 0600
gene id: 420245:LBRM_01_0600
uniprot id: A0A3P3YWK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

420245:LBRM 27 0960
gene id: 420245:LBRM_27_0960
uniprot id: A0A3P3Z9V5
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

420245:LBRM 17 1210
gene id: 420245:LBRM_17_1210
uniprot id: A0A3P3Z388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

420245:LBRM 26 2630
gene id: 420245:LBRM_26_2630
uniprot id: A0A3P3Z9R0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

420245:LBRM 26 0320
gene id: 420245:LBRM_26_0320
uniprot id: A0A3P3Z8W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

420245:LBRM 15 0210
gene id: 420245:LBRM_15_0210
uniprot id: A0A3P3Z1Z7
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

420245:LBRM 24 2370
gene id: 420245:LBRM_24_2370
uniprot id: A0A3P3Z8B8
names: Similarity
messages: Belongs to the cullin family.

420245:LBRM 16 0930
gene id: 420245:LBRM_16_0930
uniprot id: A0A3P3Z2B2
names: Function
names: Similarity
messages: Belongs to the calflagin family.
messages: May contribute to the rapid motility of the trypanosomes, playing a role either in flagellar structure or in calcium metabolism. Could alternate between a GDP-bound inactive form to a calcium/GTP-bound active form.

420245:LBRM 34 1820
gene id: 420245:LBRM_34_1820
uniprot id: A0A3P3ZGV7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

420245:LBRM 17 0090
gene id: 420245:LBRM_17_0090
uniprot id: A0A3P3Z2W9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

420245:LBRM 34 1070
gene id: 420245:LBRM_34_1070
uniprot id: A0A3P3ZGK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

420245:LBRM 34 3910
gene id: 420245:LBRM_34_3910
uniprot id: A0A3P3ZHV8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

420245:LBRM 26 0650
gene id: 420245:LBRM_26_0650
uniprot id: A0A3P3Z9C9
names: Similarity
messages: Belongs to the GroES chaperonin family.

420245:LBRM 35 6720
gene id: 420245:LBRM_35_6720
uniprot id: A0A3P3ZK52
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

420245:LBRM 14 0630
gene id: 420245:LBRM_14_0630
uniprot id: A0A3P3Z1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

420245:LBRM 05 0800
gene id: 420245:LBRM_05_0800
uniprot id: A0A3P3YXT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

420245:LBRM 25 0700
gene id: 420245:LBRM_25_0700
uniprot id: A0A3P3Z8I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

420245:LBRM 23 1320
gene id: 420245:LBRM_23_1320
uniprot id: A0A3P3Z791
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

420245:LBRM 11 0300
gene id: 420245:LBRM_11_0300
uniprot id: A0A3P3Z046
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

420245:LBRM 05 0140
gene id: 420245:LBRM_05_0140
uniprot id: A0A3P3YXN9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

420245:LBRM 34 3780
gene id: 420245:LBRM_34_3780
uniprot id: A0A3P3ZHC5
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

420245:LBRM 29 0940
gene id: 420245:LBRM_29_0940
uniprot id: A0A3P3ZBM3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

420245:LBRM 23 1720
gene id: 420245:LBRM_23_1720
uniprot id: A0A3P3Z7D4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

420245:LBRM 33 1830
gene id: 420245:LBRM_33_1830
uniprot id: A0A3P3ZFS0
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

420245:LBRM 34 4410
gene id: 420245:LBRM_34_4410
uniprot id: A0A3P3ZHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

420245:LBRM 28 0540
gene id: 420245:LBRM_28_0540
uniprot id: A0A3P3ZAG1
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

420245:LBRM 23 1650
gene id: 420245:LBRM_23_1650
uniprot id: A0A3P3Z7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

420245:LBRM 13 0900
gene id: 420245:LBRM_13_0900
uniprot id: A0A3P3Z183
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

420245:LBRM 33 1110
gene id: 420245:LBRM_33_1110
uniprot id: A0A3P3ZG98
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

420245:LBRM 02 0650
gene id: 420245:LBRM_02_0650
uniprot id: A0A3P3YWW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

420245:LBRM 27 1700
gene id: 420245:LBRM_27_1700
uniprot id: A0A3P3ZA40
names: Similarity
messages: Belongs to the diacylglycerol acyltransferase family.

420245:LBRM 35 1270
gene id: 420245:LBRM_35_1270
uniprot id: A0A3P3ZI50
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

420245:LBRM 10 0950
gene id: 420245:LBRM_10_0950
uniprot id: A0A3P3YZU0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

420245:LBRM 19 1660
gene id: 420245:LBRM_19_1660
uniprot id: A0A3P3Z416
names: Similarity
messages: Belongs to the TBP family.

420245:LBRM 25 1130
gene id: 420245:LBRM_25_1130
uniprot id: A0A3P3Z8F0
names: Function
names: Similarity
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.

420245:LBRM 05 0520
gene id: 420245:LBRM_05_0520
uniprot id: A0A3P3YXS3
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

420245:LBRM 32 0550
gene id: 420245:LBRM_32_0550
uniprot id: A0A3P3ZE84
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 34 0780
gene id: 420245:LBRM_34_0780
uniprot id: A0A3P3ZH44
names: Similarity
messages: Belongs to the actin family.

420245:LBRM 27 1600
gene id: 420245:LBRM_27_1600
uniprot id: A0A3P3ZAB2
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

420245:LBRM 33 2550
gene id: 420245:LBRM_33_2550
uniprot id: A0A3P3ZGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeSI family.
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

420245:LBRM 22 0060
gene id: 420245:LBRM_22_0060
uniprot id: A0A3P3Z6Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

420245:LBRM 09 1460
gene id: 420245:LBRM_09_1460
uniprot id: A0A3P3YZE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

420245:LBRM 16 0320
gene id: 420245:LBRM_16_0320
uniprot id: A0A3P3Z2G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

420245:LBRM 25 0940
gene id: 420245:LBRM_25_0940
uniprot id: A0A3P3Z8F1
names: Similarity
messages: Belongs to the frataxin family.

420245:LBRM 27 0990
gene id: 420245:LBRM_27_0990
uniprot id: A0A3P3ZA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

420245:LBRM 32 2960
gene id: 420245:LBRM_32_2960
uniprot id: A0A3P3ZF92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

420245:LBRM 32 3650
gene id: 420245:LBRM_32_3650
uniprot id: A0A3P3ZFB8
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 07 0200
gene id: 420245:LBRM_07_0200
uniprot id: A0A3P3YYE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

420245:LBRM 19 1290
gene id: 420245:LBRM_19_1290
uniprot id: A0A3P3Z3V4
names: Similarity
messages: Belongs to the WD repeat LST8 family.

420245:LBRM 35 2950
gene id: 420245:LBRM_35_2950
uniprot id: A0A3P3ZIL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

420245:LBRM 33 1290
gene id: 420245:LBRM_33_1290
uniprot id: A0A3P3ZFL1
names: Similarity
messages: Belongs to the guanylate kinase family.

420245:LBRM 26 0330
gene id: 420245:LBRM_26_0330
uniprot id: A0A3P3Z9A2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

420245:LBRM 28 2670
gene id: 420245:LBRM_28_2670
uniprot id: A0A3P3ZBH8
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

420245:LBRM 32 1750
gene id: 420245:LBRM_32_1750
uniprot id: A0A3P3ZEJ6
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

420245:LBRM 28 2710
gene id: 420245:LBRM_28_2710
uniprot id: A0A3P3ZB34
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

420245:LBRM 35 3540
gene id: 420245:LBRM_35_3540
uniprot id: A0A3P3ZIU2
names: Similarity
messages: Belongs to the actin family.

420245:LBRM 03 0580
gene id: 420245:LBRM_03_0580
uniprot id: A0A3P3YX55
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

420245:LBRM 24 2350
gene id: 420245:LBRM_24_2350
uniprot id: A0A3P3Z896
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

420245:LBRM 32 1570
gene id: 420245:LBRM_32_1570
uniprot id: A0A3P3ZEL1
names: Similarity
messages: Belongs to the Cyclase 1 superfamily.

420245:LBRM 33 1160
gene id: 420245:LBRM_33_1160
uniprot id: A0A3P3ZFL4
names: Similarity
messages: Belongs to the NAPRTase family.

420245:LBRM 24 1540
gene id: 420245:LBRM_24_1540
uniprot id: A0A3P3Z816
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

420245:LBRM 30 3280
gene id: 420245:LBRM_30_3280
uniprot id: A0A3P3ZD74
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

420245:LBRM 26 1960
gene id: 420245:LBRM_26_1960
uniprot id: A0A3P3Z9N8
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 34 1450
gene id: 420245:LBRM_34_1450
uniprot id: A0A3P3ZGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Membrane

420245:LBRM 18 0800
gene id: 420245:LBRM_18_0800
uniprot id: A0A3P3Z3B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

420245:LBRM 35 3290
gene id: 420245:LBRM_35_3290
uniprot id: A0A3P3ZIR1
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

420245:LBRM 25 0190
gene id: 420245:LBRM_25_0190
uniprot id: A0A3P3Z862
names: Similarity
messages: Belongs to the peptidase C12 family.

420245:LBRM 28 2630
gene id: 420245:LBRM_28_2630
uniprot id: A0A3P3ZB97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

420245:LBRM 14 0140
gene id: 420245:LBRM_14_0140
uniprot id: A0A3P3Z1H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

420245:LBRM 33 0600
gene id: 420245:LBRM_33_0600
uniprot id: A0A3P3ZFU9
names: Similarity
messages: Belongs to the NKAP family.

420245:LBRM 26 2140
gene id: 420245:LBRM_26_2140
uniprot id: A0A3P3Z9S2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

420245:LBRM 32 1190
gene id: 420245:LBRM_32_1190
uniprot id: A0A3P3ZEQ1
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.

420245:LBRM 07 0960
gene id: 420245:LBRM_07_0960
uniprot id: A0A3P3YYL1
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 28 0650
gene id: 420245:LBRM_28_0650
uniprot id: A0A3P3ZAV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 01 0690
gene id: 420245:LBRM_01_0690
uniprot id: A0A3P3YWM0
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

420245:LBRM 22 0760
gene id: 420245:LBRM_22_0760
uniprot id: A0A3P3Z6P8
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

420245:LBRM 08 0730
gene id: 420245:LBRM_08_0730
uniprot id: A0A3P3YZ79
names: Similarity
messages: Belongs to the RNase Z family.

420245:LBRM 31 0190
gene id: 420245:LBRM_31_0190
uniprot id: A0A3P3ZBW8
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

420245:LBRM 34 2970
gene id: 420245:LBRM_34_2970
uniprot id: A0A3P3ZHM6
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

420245:LBRM 35 4740
gene id: 420245:LBRM_35_4740
uniprot id: A0A3P3ZJ47
names: Similarity
messages: Belongs to the CFAP298 family.

420245:LBRM 29 1820
gene id: 420245:LBRM_29_1820
uniprot id: A0A3P3ZBU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 35 3490
gene id: 420245:LBRM_35_3490
uniprot id: A0A3P3ZJ54
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

420245:LBRM 32 1900
gene id: 420245:LBRM_32_1900
uniprot id: A0A3P3ZEK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

420245:LBRM 34 0360
gene id: 420245:LBRM_34_0360
uniprot id: A0A3P3ZGR9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

420245:LBRM 07 0750
gene id: 420245:LBRM_07_0750
uniprot id: A0A3P3YYK4
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

420245:LBRM 28 2620
gene id: 420245:LBRM_28_2620
uniprot id: A0A3P3ZB25
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

420245:LBRM 34 3600
gene id: 420245:LBRM_34_3600
uniprot id: A0A3P3ZH87
names: Similarity
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.

420245:LBRM 32 3550
gene id: 420245:LBRM_32_3550
uniprot id: A0A3P3ZF14
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.

420245:LBRM 16 0570
gene id: 420245:LBRM_16_0570
uniprot id: A0A3P3Z2I2
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

420245:LBRM 15 1190
gene id: 420245:LBRM_15_1190
uniprot id: A0A3P3Z280
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

420245:LBRM 35 1390
gene id: 420245:LBRM_35_1390
uniprot id: A0A3P3ZI57
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

420245:LBRM 10 0210
gene id: 420245:LBRM_10_0210
uniprot id: A0A3P3YZI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

420245:LBRM 23 0050
gene id: 420245:LBRM_23_0050
uniprot id: A0A3P3Z765
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

420245:LBRM 30 3430
gene id: 420245:LBRM_30_3430
uniprot id: A0A3P3ZD69
names: Similarity
messages: Belongs to the XPO2/CSE1 family.

420245:LBRM 26 1830
gene id: 420245:LBRM_26_1830
uniprot id: A0A3P3Z9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Nucleus

420245:LBRM 19 1180
gene id: 420245:LBRM_19_1180
uniprot id: A0A3P3Z3U6
names: Similarity
messages: Belongs to the ATG8 family.

420245:LBRM 34 1150
gene id: 420245:LBRM_34_1150
uniprot id: A0A3P3ZGM6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

420245:LBRM 05 0490
gene id: 420245:LBRM_05_0490
uniprot id: A0A3P3YXQ5
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 35 4600
gene id: 420245:LBRM_35_4600
uniprot id: A0A3P3ZJI5
names: Similarity
messages: Belongs to the AAA ATPase family.

420245:LBRM 25 0240
gene id: 420245:LBRM_25_0240
uniprot id: A0A3P3Z8K0
names: Similarity
messages: Belongs to the CWC26 family.

420245:LBRM 07 1110
gene id: 420245:LBRM_07_1110
uniprot id: A0A3P3YYQ8
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

420245:LBRM 23 0020
gene id: 420245:LBRM_23_0020
uniprot id: A0A3P3Z6X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

420245:LBRM 15 0820
gene id: 420245:LBRM_15_0820
uniprot id: A0A3P3Z1X3
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 18 0700
gene id: 420245:LBRM_18_0700
uniprot id: A0A3P3Z380
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

420245:LBRM 25 1270
gene id: 420245:LBRM_25_1270
uniprot id: A0A3P3Z8W0
names: Similarity
messages: Belongs to the PPP4R2 family.

420245:LBRM 28 2310
gene id: 420245:LBRM_28_2310
uniprot id: A0A3P3ZBE4
names: Similarity
messages: Belongs to the cullin family.

420245:LBRM 28 1460
gene id: 420245:LBRM_28_1460
uniprot id: A0A3P3YX29
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 29 2570
gene id: 420245:LBRM_29_2570
uniprot id: A0A3P3ZC34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

420245:LBRM 35 6760
gene id: 420245:LBRM_35_6760
uniprot id: A0A3P3ZJY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 19 0020
gene id: 420245:LBRM_19_0020
uniprot id: A0A3P3Z017
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 08 0010
gene id: 420245:LBRM_08_0010
uniprot id: A0A3P3YYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

420245:LBRM 14 1440
gene id: 420245:LBRM_14_1440
uniprot id: A0A3P3Z1K5
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

420245:LBRM 28 2050
gene id: 420245:LBRM_28_2050
uniprot id: A0A3P3ZAW6
names: Subcellular Location Annotation
messages: nucleolus

420245:LBRM 28 1650
gene id: 420245:LBRM_28_1650
uniprot id: A0A3P3ZAR8
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 10 1450
gene id: 420245:LBRM_10_1450
uniprot id: A0A3P3Z007
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

420245:LBRM 32 1010
gene id: 420245:LBRM_32_1010
uniprot id: A0A3P3ZEM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

420245:LBRM 29 1720
gene id: 420245:LBRM_29_1720
uniprot id: A0A3P3ZBV1
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 28 3030
gene id: 420245:LBRM_28_3030
uniprot id: A0A3P3ZBD3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

420245:LBRM 27 2050
gene id: 420245:LBRM_27_2050
uniprot id: A0A3P3ZA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

420245:LBRM 22 1440
gene id: 420245:LBRM_22_1440
uniprot id: A0A3P3Z6V5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

420245:LBRM 13 0970
gene id: 420245:LBRM_13_0970
uniprot id: A0A3P3Z104
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Parasitic protozoa lack the de novo purine biosynthesis pathway and rely exclusively on the salvage pathway for their purine nucleotide requirements.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.
messages: Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

420245:LBRM 31 0510
gene id: 420245:LBRM_31_0510
uniprot id: A0A3P3ZDB0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 34 2390
gene id: 420245:LBRM_34_2390
uniprot id: A0A3P3ZGY4
names: Similarity
messages: Belongs to the FAH family.

420245:LBRM 29 0070
gene id: 420245:LBRM_29_0070
uniprot id: A0A3P3ZBA4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

420245:LBRM 35 1900
gene id: 420245:LBRM_35_1900
uniprot id: A0A3P3ZIQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

420245:LBRM 33 3540
gene id: 420245:LBRM_33_3540
uniprot id: A0A3P3ZGX9
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 26 1730
gene id: 420245:LBRM_26_1730
uniprot id: A0A3P3Z9G2
names: Similarity
messages: Belongs to the MGMT family.

420245:LBRM 01 0320
gene id: 420245:LBRM_01_0320
uniprot id: A0A3P3YWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

420245:LBRM 21 1740
gene id: 420245:LBRM_21_1740
uniprot id: A0A3P3Z6D7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

420245:LBRM 25 0840
gene id: 420245:LBRM_25_0840
uniprot id: A0A3P3Z8R5
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

420245:LBRM 27 0480
gene id: 420245:LBRM_27_0480
uniprot id: A0A3P3Z9X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

420245:LBRM 05 0940
gene id: 420245:LBRM_05_0940
uniprot id: A0A3P3YXV2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

420245:LBRM 34 3400
gene id: 420245:LBRM_34_3400
uniprot id: A0A3P3ZH88
names: Similarity
messages: Belongs to the syntaxin family.

420245:LBRM 24 0620
gene id: 420245:LBRM_24_0620
uniprot id: A0A3P3Z7K3
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 35 3280
gene id: 420245:LBRM_35_3280
uniprot id: A0A3P3ZIQ3
names: Similarity
messages: Belongs to the cullin family.

420245:LBRM 35 2400
gene id: 420245:LBRM_35_2400
uniprot id: A0A3P3ZIN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

420245:LBRM 32 3220
gene id: 420245:LBRM_32_3220
uniprot id: A0A3P3ZEY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

420245:LBRM 27 1050
gene id: 420245:LBRM_27_1050
uniprot id: A0A3P3ZA59
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 13 0880
gene id: 420245:LBRM_13_0880
uniprot id: A0A3P3Z156
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

420245:LBRM 22 1300
gene id: 420245:LBRM_22_1300
uniprot id: A0A3P3Z6U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

420245:LBRM 35 6830
gene id: 420245:LBRM_35_6830
uniprot id: A0A3P3ZK65
names: Similarity
messages: Belongs to the UFD1 family.

420245:LBRM 35 5000
gene id: 420245:LBRM_35_5000
uniprot id: A0A3P3ZJ82
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 19 0990
gene id: 420245:LBRM_19_0990
uniprot id: A0A3P3Z3S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP11 family.
messages: nucleolus

420245:LBRM 35 4220
gene id: 420245:LBRM_35_4220
uniprot id: A0A3P3ZJ77
names: Similarity
messages: Belongs to the CDC73 family.

420245:LBRM 19 0360
gene id: 420245:LBRM_19_0360
uniprot id: A0A3P3Z3L5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 29 1840
gene id: 420245:LBRM_29_1840
uniprot id: A0A3P3ZBW2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

420245:LBRM 35 4070
gene id: 420245:LBRM_35_4070
uniprot id: A0A3P3ZIZ0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

420245:LBRM 12 0930
gene id: 420245:LBRM_12_0930
uniprot id: A0A3P3Z0U0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

420245:LBRM 30 0050
gene id: 420245:LBRM_30_0050
uniprot id: A0A3P3ZC72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

420245:LBRM 29 0030
gene id: 420245:LBRM_29_0030
uniprot id: A0A3P3ZBB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

420245:LBRM 30 3630
gene id: 420245:LBRM_30_3630
uniprot id: A0A3P3ZD76
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

420245:LBRM 30 1070
gene id: 420245:LBRM_30_1070
uniprot id: A0A3P3ZCF1
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 18 0920
gene id: 420245:LBRM_18_0920
uniprot id: A0A3P3Z3C0
names: Similarity
messages: Belongs to the WD repeat PWP2 family.

420245:LBRM 11 0230
gene id: 420245:LBRM_11_0230
uniprot id: A0A3P3Z734
names: Subcellular Location Annotation
messages: nucleolus

420245:LBRM 14 0620
gene id: 420245:LBRM_14_0620
uniprot id: A0A3P3Z1H3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

420245:LBRM 15 0230
gene id: 420245:LBRM_15_0230
uniprot id: A0A3P3Z1R6
names: Similarity
messages: Belongs to the PPP phosphatase family.

420245:LBRM 34 0430
gene id: 420245:LBRM_34_0430
uniprot id: A0A3P3ZGC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

420245:LBRM 34 5090
gene id: 420245:LBRM_34_5090
uniprot id: A0A3P3ZI41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

420245:LBRM 33 1910
gene id: 420245:LBRM_33_1910
uniprot id: A0A3P3ZGH3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

420245:LBRM 31 3630
gene id: 420245:LBRM_31_3630
uniprot id: A0A3P3ZHT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

420245:LBRM 35 3090
gene id: 420245:LBRM_35_3090
uniprot id: A0A3P3ZIM7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

420245:LBRM 21 1390
gene id: 420245:LBRM_21_1390
uniprot id: A0A3P3Z680
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: Monomer.

420245:LBRM 32 2030
gene id: 420245:LBRM_32_2030
uniprot id: A0A3P3ZEP2
names: Function
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.
messages: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

420245:LBRM 14 0720
gene id: 420245:LBRM_14_0720
uniprot id: A0A3P3Z1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

420245:LBRM 35 0760
gene id: 420245:LBRM_35_0760
uniprot id: A0A3P3ZI00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

420245:LBRM 32 3230
gene id: 420245:LBRM_32_3230
uniprot id: A0A3P3ZFL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

420245:LBRM 35 6730
gene id: 420245:LBRM_35_6730
uniprot id: A0A3P3ZK61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

420245:LBRM 28 1380
gene id: 420245:LBRM_28_1380
uniprot id: A0A3P3ZB08
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

420245:LBRM 07 0230
gene id: 420245:LBRM_07_0230
uniprot id: A0A3P3YYF9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Monomer.

420245:LBRM 28 2401
gene id: 420245:LBRM_28_2401
uniprot id: A0A3P3ZBF2
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

420245:LBRM 05 0270
gene id: 420245:LBRM_05_0270
uniprot id: A0A3P3YXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Membrane

420245:LBRM 28 2510
gene id: 420245:LBRM_28_2510
uniprot id: A0A3P3ZB14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

420245:LBRM 14 1190
gene id: 420245:LBRM_14_1190
uniprot id: A0A3P3Z4K4
names: Similarity
messages: Belongs to the TPPP family.

420245:LBRM 34 1960
gene id: 420245:LBRM_34_1960
uniprot id: A0A3P3ZHC3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

420245:LBRM 10 0060
gene id: 420245:LBRM_10_0060
uniprot id: A0A3P3YZK5
names: Similarity
messages: Belongs to the thymidylate kinase family.

420245:LBRM 25 0630
gene id: 420245:LBRM_25_0630
uniprot id: A0A3P3Z8M0
names: Similarity
messages: Belongs to the PP2C family.

420245:LBRM 01 0490
gene id: 420245:LBRM_01_0490
uniprot id: A0A3P3YWQ3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

420245:LBRM 33 2670
gene id: 420245:LBRM_33_2670
uniprot id: A0A3P3ZGA2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

420245:LBRM 09 0630
gene id: 420245:LBRM_09_0630
uniprot id: A0A3P3YZK2
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 25 1510
gene id: 420245:LBRM_25_1510
uniprot id: A0A3P3Z8U0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

420245:LBRM 14 1360
gene id: 420245:LBRM_14_1360
uniprot id: A0A3P3Z1J7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

420245:LBRM 30 1840
gene id: 420245:LBRM_30_1840
uniprot id: A0A3P3ZDB5
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 33 1960
gene id: 420245:LBRM_33_1960
uniprot id: A0A3P3ZG32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

420245:LBRM 02 0310
gene id: 420245:LBRM_02_0310
uniprot id: A0A3P3YWT0
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 34 2840
gene id: 420245:LBRM_34_2840
uniprot id: A0A3P3ZH27
names: Similarity
messages: Belongs to the polyprenol kinase family.

420245:LBRM 33 2280
gene id: 420245:LBRM_33_2280
uniprot id: A0A3P3ZG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Membrane

420245:LBRM 35 6400
gene id: 420245:LBRM_35_6400
uniprot id: A0A3P3ZK31
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

420245:LBRM 34 2140
gene id: 420245:LBRM_34_2140
uniprot id: A0A3P3ZHE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KMP-11 family.
messages: Monomer.
messages: cytoskeleton

420245:LBRM 35 7120
gene id: 420245:LBRM_35_7120
uniprot id: A0A3P3ZK74
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

420245:LBRM 10 0110
gene id: 420245:LBRM_10_0110
uniprot id: A0A3P3YZH4
names: Function
names: Similarity
messages: Belongs to the WD repeat CIA1 family.
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

420245:LBRM 09 0420
gene id: 420245:LBRM_09_0420
uniprot id: A0A3P3YZ48
names: Similarity
messages: Belongs to the protein kinase superfamily.

420245:LBRM 34 1790
gene id: 420245:LBRM_34_1790
uniprot id: A0A3P3ZGS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

420245:LBRM 08 0880
gene id: 420245:LBRM_08_0880
uniprot id: A0A3P3YYZ0
names: Subcellular Location Annotation
messages: Cytoplasm

420245:LBRM 13 0100
gene id: 420245:LBRM_13_0100
uniprot id: A0A3P3Z0P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

420245:LBRM 32 0520
gene id: 420245:LBRM_32_0520
uniprot id: A0A3P3ZE81
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

420245:LBRM 34 0760
gene id: 420245:LBRM_34_0760
uniprot id: A0A3P3ZGJ6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 22 0090
gene id: 420245:LBRM_22_0090
uniprot id: A0A3P3Z6I7
names: Similarity
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.

420245:LBRM 34 3010
gene id: 420245:LBRM_34_3010
uniprot id: A0A3P3ZHB6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G.

420245:LBRM 19 1800
gene id: 420245:LBRM_19_1800
uniprot id: A0A3P3Z413
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

420245:LBRM 02 0400
gene id: 420245:LBRM_02_0400
uniprot id: A0A3P3YWS5
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

420245:LBRM 04 0780
gene id: 420245:LBRM_04_0780
uniprot id: A0A3P3YXG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pescadillo family.
messages: Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
messages: nucleolus
messages: nucleoplasm

420245:LBRM 33 0570
gene id: 420245:LBRM_33_0570
uniprot id: A0A3P3ZFX0
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

420245:LBRM 32 0300
gene id: 420245:LBRM_32_0300
uniprot id: A0A3P3ZE56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

420245:LBRM 27 2220
gene id: 420245:LBRM_27_2220
uniprot id: A0A3P3ZAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

420245:LBRM 32 4220
gene id: 420245:LBRM_32_4220
uniprot id: A0A3P3ZFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Belongs to the NAF1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

420245:LBRM 12 0170
gene id: 420245:LBRM_12_0170
uniprot id: A0A3P3Z0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APH-1 family.
messages: Membrane

420245:LBRM 30 1480
gene id: 420245:LBRM_30_1480
uniprot id: A0A3P3ZCM0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

420245:LBRM 18 1070
gene id: 420245:LBRM_18_1070
uniprot id: A0A3P3Z3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: cytoskeleton

420245:LBRM 31 3480
gene id: 420245:LBRM_31_3480
uniprot id: A0A3P3ZE27
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 07 0090
gene id: 420245:LBRM_07_0090
uniprot id: A0A3P3YYD6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

420245:LBRM 04 0610
gene id: 420245:LBRM_04_0610
uniprot id: A0A3P3YXK9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

420245:LBRM 26 0270
gene id: 420245:LBRM_26_0270
uniprot id: A0A3P3Z8V8
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

420245:LBRM 05 0100
gene id: 420245:LBRM_05_0100
uniprot id: A0A3P3YXN6
names: Similarity
messages: Belongs to the PPP phosphatase family.

420245:LBRM 30 3580
gene id: 420245:LBRM_30_3580
uniprot id: A0A3P3ZD54
names: Similarity
messages: Belongs to the cytochrome P450 family.

420245:LBRM 14 0700
gene id: 420245:LBRM_14_0700
uniprot id: A0A3P3Z1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

420245:LBRM 28 1670
gene id: 420245:LBRM_28_1670
uniprot id: A0A3P3ZAT5
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 15 0540
gene id: 420245:LBRM_15_0540
uniprot id: A0A3P3Z1T2
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

420245:LBRM 02 0420
gene id: 420245:LBRM_02_0420
uniprot id: A0A3P3YWS8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

420245:LBRM 27 2010
gene id: 420245:LBRM_27_2010
uniprot id: A0A3P3ZAF3
names: Similarity
messages: In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.

420245:LBRM 19 0510
gene id: 420245:LBRM_19_0510
uniprot id: A0A3P3Z3N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

420245:LBRM 26 0030
gene id: 420245:LBRM_26_0030
uniprot id: A0A3P3Z8S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

420245:LBRM 35 5340
gene id: 420245:LBRM_35_5340
uniprot id: A0A3P3ZJA5
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Tetramer of two alpha and two beta subunits.

420245:LBRM 14 0670
gene id: 420245:LBRM_14_0670
uniprot id: A0A3P3Z1B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

420245:LBRM 33 2510
gene id: 420245:LBRM_33_2510
uniprot id: A0A3P3ZG18
names: Similarity
messages: Belongs to the CFAP91 family.

420245:LBRM 31 0250
gene id: 420245:LBRM_31_0250
uniprot id: A0A3P3ZBW3
names: Similarity
messages: Belongs to the PIH1 family.

420245:LBRM 32 3240
gene id: 420245:LBRM_32_3240
uniprot id: A0A3P3ZFC5
names: Similarity
messages: Belongs to the phosducin family.

420245:LBRM 21 1580
gene id: 420245:LBRM_21_1580
uniprot id: A0A3P3Z6A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

420245:LBRM 32 2870
gene id: 420245:LBRM_32_2870
uniprot id: A0A3P3ZEU9
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

420245:LBRM 32 3140
gene id: 420245:LBRM_32_3140
uniprot id: A0A3P3ZFA8
names: Similarity
messages: Belongs to the SNAP family.

420245:LBRM 24 0040
gene id: 420245:LBRM_24_0040
uniprot id: A0A3P3Z7M1
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

420245:LBRM 35 2870
gene id: 420245:LBRM_35_2870
uniprot id: A0A3P3ZIK7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

420245:LBRM 27 2550
gene id: 420245:LBRM_27_2550
uniprot id: A0A3P3ZA96
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

420245:LBRM 33 2060
gene id: 420245:LBRM_33_2060
uniprot id: A0A3P3ZFV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

420245:LBRM 26 0890
gene id: 420245:LBRM_26_0890
uniprot id: A0A3P3Z952
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

420245:LBRM 29 0910
gene id: 420245:LBRM_29_0910
uniprot id: A0A3P3ZBJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

420245:LBRM 01 0420
gene id: 420245:LBRM_01_0420
uniprot id: A0A3P3YWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

420245:LBRM 28 0250
gene id: 420245:LBRM_28_0250
uniprot id: A0A3P3ZAQ8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

420245:LBRM 15 1150
gene id: 420245:LBRM_15_1150
uniprot id: A0A3P3Z2A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: P1 and P2 exist as dimers at the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

420245:LBRM 22 1540
gene id: 420245:LBRM_22_1540
uniprot id: A0A3P3Z6W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

420245:LBRM 35 7150
gene id: 420245:LBRM_35_7150
uniprot id: A0A3P3ZKA0
names: Similarity
messages: Belongs to the AFG1 ATPase family.

420245:LBRM 15 1040
gene id: 420245:LBRM_15_1040
uniprot id: A0A3P3Z1Y7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

420245:LBRM 33 1510
gene id: 420245:LBRM_33_1510
uniprot id: A0A3P3ZFP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

420245:LBRM 12 0020
gene id: 420245:LBRM_12_0020
uniprot id: A0A3P3Z0D8
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

420245:LBRM 31 1980
gene id: 420245:LBRM_31_1980
uniprot id: A0A3P3ZDQ1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

420245:LBRM 32 4030
gene id: 420245:LBRM_32_4030
uniprot id: A0A3P3ZFM0
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

420245:LBRM 28 2870
gene id: 420245:LBRM_28_2870
uniprot id: A0A3P3ZBJ2
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.

420245:LBRM 35 5310
gene id: 420245:LBRM_35_5310
uniprot id: A0A3P3ZJQ7
names: Similarity
messages: Belongs to the NOB1 family.

420245:LBRM 19 0630
gene id: 420245:LBRM_19_0630
uniprot id: A0A3P3Z3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

420245:LBRM 32 1460
gene id: 420245:LBRM_32_1460
uniprot id: A0A3P3ZEG3
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.

420245:LBRM 15 0900
gene id: 420245:LBRM_15_0900
uniprot id: A0A3P3Z1V8
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 26 1650
gene id: 420245:LBRM_26_1650
uniprot id: A0A3P3Z9D6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

420245:LBRM 27 1680
gene id: 420245:LBRM_27_1680
uniprot id: A0A3P3ZA84
names: Function
names: Similarity
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.

420245:LBRM 30 3420
gene id: 420245:LBRM_30_3420
uniprot id: A0A3P3ZD51
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

420245:LBRM 22 1080
gene id: 420245:LBRM_22_1080
uniprot id: A0A3P3Z6S3
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

420245:LBRM 35 5900
gene id: 420245:LBRM_35_5900
uniprot id: A0A3P3ZJP3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

420245:LBRM 27 2160
gene id: 420245:LBRM_27_2160
uniprot id: A0A3P3ZA73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
messages: nucleolus

420245:LBRM 31 0720
gene id: 420245:LBRM_31_0720
uniprot id: A0A3P3ZDD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Cytoplasm

420245:LBRM 34 1340
gene id: 420245:LBRM_34_1340
uniprot id: A0A3P3ZGM5
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

420245:LBRM 34 1800
gene id: 420245:LBRM_34_1800
uniprot id: A0A3P3ZGS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

420245:LBRM 28 1950
gene id: 420245:LBRM_28_1950
uniprot id: A0A3P3ZB23
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

420245:LBRM 25 0360
gene id: 420245:LBRM_25_0360
uniprot id: A0A3P3Z8E6
names: Similarity
messages: Belongs to the DENR family.

420245:LBRM 32 4160
gene id: 420245:LBRM_32_4160
uniprot id: A0A3P3ZFM6
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

420245:LBRM 11 0880
gene id: 420245:LBRM_11_0880
uniprot id: A0A3P3Z0A9
names: Similarity
messages: Belongs to the cytochrome P450 family.

420245:LBRM 32 0570
gene id: 420245:LBRM_32_0570
uniprot id: A0A3P3ZE85
names: Similarity
messages: Belongs to the profilin family.

420245:LBRM 13 0190
gene id: 420245:LBRM_13_0190
uniprot id: A0A3P3Z0R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

420245:LBRM 32 4060
gene id: 420245:LBRM_32_4060
uniprot id: A0A3P3ZF77
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 32 2270
gene id: 420245:LBRM_32_2270
uniprot id: A0A3P3ZEN4
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 04 0030
gene id: 420245:LBRM_04_0030
uniprot id: A0A3P3YXE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

420245:LBRM 15 1100
gene id: 420245:LBRM_15_1100
uniprot id: A0A3P3Z274
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

420245:LBRM 17 1240
gene id: 420245:LBRM_17_1240
uniprot id: A0A3P3Z307
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

420245:LBRM 08 0090
gene id: 420245:LBRM_08_0090
uniprot id: A0A3P3YYR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 3 (AP-3) is a heterotetramer.
messages: Belongs to the adaptor complexes large subunit family.
messages: Golgi apparatus

420245:LBRM 18 1610
gene id: 420245:LBRM_18_1610
uniprot id: A0A3P3Z3K6
names: Similarity
messages: Belongs to the IUNH family.

420245:LBRM 35 3110
gene id: 420245:LBRM_35_3110
uniprot id: A0A3P3ZIN9
names: Subcellular Location Annotation
messages: Membrane

420245:LBRM 30 1940
gene id: 420245:LBRM_30_1940
uniprot id: A0A3P3ZCQ8
names: Similarity
messages: Belongs to the APC1 family.

420245:LBRM 26 0050
gene id: 420245:LBRM_26_0050
uniprot id: A0A3P3Z904
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

420245:LBRM 32 2580
gene id: 420245:LBRM_32_2580
uniprot id: A0A3P3ZER6
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

420245:LBRM 28 1700
gene id: 420245:LBRM_28_1700
uniprot id: A0A3P3ZAW2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G.

420245:LBRM 04 0520
gene id: 420245:LBRM_04_0520
uniprot id: A0A3P3YXF0
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

420245:LBRM 05 0980
gene id: 420245:LBRM_05_0980
uniprot id: A0A3P3YXY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

420245:LBRM 22 0010
gene id: 420245:LBRM_22_0010
uniprot id: A0A3P3Z6I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Membrane

420245:LBRM 29 2800
gene id: 420245:LBRM_29_2800
uniprot id: A0A3P3ZC60
names: Similarity
messages: Belongs to the actin family.

420245:LBRM 22 0560
gene id: 420245:LBRM_22_0560
uniprot id: A0A3P3Z6N5
names: Similarity
messages: Belongs to the AAA ATPase family.

420245:LBRM 29 1130
gene id: 420245:LBRM_29_1130
uniprot id: A0A3P3ZBN0
names: Subcellular Location Annotation
messages: Nucleus

420245:LBRM 35 5650
gene id: 420245:LBRM_35_5650
uniprot id: A0A3P3ZJV8
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

420245:LBRM 30 0030
gene id: 420245:LBRM_30_0030
uniprot id: A0A3P3ZC81
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

420245:LBRM 27 2180
gene id: 420245:LBRM_27_2180
uniprot id: A0A3P3ZAC5
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

420245:LBRM 19 1710
gene id: 420245:LBRM_19_1710
uniprot id: A0A3P3Z483
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

420245:LBRM 24 0630
gene id: 420245:LBRM_24_0630
uniprot id: A0A3P3Z7P4
names: Similarity
messages: Belongs to the peptidase C19 family.

420245:LBRM 33 0900
gene id: 420245:LBRM_33_0900
uniprot id: A0A3P3Z6G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
messages: Peroxisome membrane

420245:LBRM 34 4690
gene id: 420245:LBRM_34_4690
uniprot id: A0A3P3ZHR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

420245:LBRM 25 0590
gene id: 420245:LBRM_25_0590
uniprot id: A0A3P3Z8A2
names: Function
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

420245:LBRM 35 1540
gene id: 420245:LBRM_35_1540
uniprot id: A0A3P3ZIE0
names: Similarity
messages: Belongs to the CFAP36 family.