419612:LOC102519874
gene id: 419612:LOC102519874
uniprot id: S9W978
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:PI4K2A
gene id: 419612:PI4K2A
uniprot id: A0A8B8TXL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

419612:PIAS2
gene id: 419612:PIAS2
uniprot id: A0A8B8S8I6
uniprot id: A0A8B8S9T1
uniprot id: A0A8B8S9Y6
uniprot id: A0A8B8SAS2
names: Similarity
messages: Belongs to the PIAS family.

419612:SPTA1
gene id: 419612:SPTA1
uniprot id: A0A8B6Y9G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

419612:LOC106730863
gene id: 419612:LOC106730863
uniprot id: A0A8B8U8S3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

419612:ANP32A
gene id: 419612:ANP32A
uniprot id: A0A8B6Y7Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

419612:LOC102523613
gene id: 419612:LOC102523613
uniprot id: A0A8B6YLC9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

419612:TFAP2A
gene id: 419612:TFAP2A
uniprot id: A0A8B8RK93
uniprot id: A0A8B8RK99
uniprot id: A0A8B8RKA2
uniprot id: A0A8B8RKK6
uniprot id: A0A8B8RM21
uniprot id: A0A8B8RMI5
uniprot id: A0A8B8RMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

419612:TFR2
gene id: 419612:TFR2
uniprot id: A0A8B8RC57
uniprot id: A0A8B8RC62
uniprot id: A0A8B8RC65
uniprot id: A0A8B8RE97
uniprot id: A0A8B8REA2
uniprot id: A0A8B8RER2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

419612:PRKG2
gene id: 419612:PRKG2
uniprot id: A0A8B8R471
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

419612:ELOF1
gene id: 419612:ELOF1
uniprot id: A0A8B6YJK1
uniprot id: A0A8B8RUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

419612:CSTF2T
gene id: 419612:CSTF2T
uniprot id: A0A8B6YDX8
names: Subcellular Location Annotation
messages: Nucleus

419612:DOP1A
gene id: 419612:DOP1A
uniprot id: A0A8B8TDU9
uniprot id: A0A8B8TDV1
uniprot id: A0A8B8TE00
uniprot id: A0A8B8TF51
names: Similarity
messages: Belongs to the dopey family.

419612:GSC
gene id: 419612:GSC
uniprot id: A0A8B8T881
names: Subcellular Location Annotation
messages: Nucleus

419612:VAMP7
gene id: 419612:VAMP7
uniprot id: A0A8B8SN37
names: Similarity
messages: Belongs to the synaptobrevin family.

419612:PER2
gene id: 419612:PER2
uniprot id: A0A8B8T2R5
uniprot id: A0A8B8T3G3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

419612:GRIK5
gene id: 419612:GRIK5
uniprot id: A0A8B8THU0
uniprot id: A0A8B8THV7
uniprot id: A0A8B8THW2
uniprot id: A0A8B8THX0
uniprot id: A0A8B8TJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

419612:FAM118B
gene id: 419612:FAM118B
uniprot id: A0A8B8SDH2
uniprot id: A0A8B8SEM7
uniprot id: A0A8B8SES2
names: Similarity
messages: Belongs to the FAM118 family.

419612:ST8SIA5
gene id: 419612:ST8SIA5
uniprot id: A0A8B6YEW3
uniprot id: A0A8B7K989
uniprot id: A0A8B7K9A0
uniprot id: A0A8B7K9V7
uniprot id: A0A8B7KBC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

419612:HACD4
gene id: 419612:HACD4
uniprot id: A0A8B8STW9
uniprot id: A0A8B8SVB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC102520892
gene id: 419612:LOC102520892
uniprot id: A0A8B8U8Y6
names: Similarity
messages: Belongs to the CFAP144 family.

419612:SURF6
gene id: 419612:SURF6
uniprot id: A0A8B8SXJ6
uniprot id: A0A8B8SXS9
uniprot id: A0A8B8SY11
names: Similarity
messages: Belongs to the SURF6 family.

419612:GIMAP2
gene id: 419612:GIMAP2
uniprot id: A0A8B7KIT3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

419612:RPGRIP1
gene id: 419612:RPGRIP1
uniprot id: A0A8B8T5J3
uniprot id: A0A8B8T5M6
uniprot id: A0A8B8T6F3
names: Similarity
messages: Belongs to the RPGRIP1 family.

419612:STAG2
gene id: 419612:STAG2
uniprot id: A0A8B7KH22
uniprot id: A0A8B8SPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

419612:IER5L
gene id: 419612:IER5L
uniprot id: A0A8B8SWZ2
names: Similarity
messages: Belongs to the IER family.

419612:P2RY8
gene id: 419612:P2RY8
uniprot id: A0A8B8SLR8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:CRYGN
gene id: 419612:CRYGN
uniprot id: A0A8B8T9V0
uniprot id: A0A8B8TA65
uniprot id: A0A8B8TA70
uniprot id: A0A8B8TAT7
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

419612:RRP15
gene id: 419612:RRP15
uniprot id: A0A8B7KC81
names: Similarity
messages: Belongs to the RRP15 family.

419612:FURIN
gene id: 419612:FURIN
uniprot id: A0A8B8S4N0
uniprot id: A0A8B8S5Z6
names: Similarity
messages: Belongs to the peptidase S8 family.

419612:ELAC1
gene id: 419612:ELAC1
uniprot id: A0A8B8S7X0
uniprot id: S9WW24
names: Subunit
messages: Homodimer.

419612:EPC2
gene id: 419612:EPC2
uniprot id: A0A8B8SZ38
uniprot id: A0A8B8SZ50
uniprot id: A0A8B8SZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

419612:LOC102515633
gene id: 419612:LOC102515633
uniprot id: A0A8B8SKA5
uniprot id: A0A8B8SML0
names: Similarity
messages: Belongs to the sulfatase family.

419612:ODAM
gene id: 419612:ODAM
uniprot id: A0A8B6YIY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ODAM family.
messages: Cytoplasm
messages: Interacts (via C-terminus) with ARHGEF5.
messages: Nucleus
messages: Secreted
messages: Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface.

419612:PARK7
gene id: 419612:PARK7
uniprot id: A0A8B8U8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

419612:CDKN1A
gene id: 419612:CDKN1A
uniprot id: A0A8B7KHV5
uniprot id: A0A8B8RLN2
names: Similarity
messages: Belongs to the CDI family.

419612:PDXK
gene id: 419612:PDXK
uniprot id: A0A8B8UD42
uniprot id: A0A8B8UD68
names: Similarity
messages: Belongs to the pyridoxine kinase family.

419612:SIN3A
gene id: 419612:SIN3A
uniprot id: A0A8B8S5W5
names: Subcellular Location Annotation
messages: Nucleus

419612:DHRS3
gene id: 419612:DHRS3
uniprot id: A0A8B8U952
uniprot id: A0A8B8UAB6
uniprot id: T0MIK7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:PSAT1
gene id: 419612:PSAT1
uniprot id: A0A8B6YJ89
uniprot id: A0A8B8SUK0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

419612:PAQR7
gene id: 419612:PAQR7
uniprot id: A0A8B7KD23
uniprot id: A0A8B8UAS2
uniprot id: A0A8B8UAX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

419612:CCR7
gene id: 419612:CCR7
uniprot id: A0A8B6YN20
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:TBC1D7
gene id: 419612:TBC1D7
uniprot id: A0A8B7K8H1
uniprot id: A0A8B7KAL2
uniprot id: A0A8B8RKN2
uniprot id: A0A8B8RML4
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

419612:SEPTIN12
gene id: 419612:SEPTIN12
uniprot id: A0A8B7K4B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

419612:NELFE
gene id: 419612:NELFE
uniprot id: A0A8B6YDY8
uniprot id: A0A8B7K6E1
uniprot id: A0A8B8RNA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

419612:LOC102521104
gene id: 419612:LOC102521104
uniprot id: A0A8B8U5X0
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

419612:ACVR2A
gene id: 419612:ACVR2A
uniprot id: A0A8B6YJB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

419612:TMEM163
gene id: 419612:TMEM163
uniprot id: A0A8B8SZZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

419612:LOC106730224
gene id: 419612:LOC106730224
uniprot id: A0A8B8RDK4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:PSEN2
gene id: 419612:PSEN2
uniprot id: A0A8B6YIG7
uniprot id: A0A8B7KCH4
uniprot id: A0A8B8RWZ5
uniprot id: A0A8B8RYQ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

419612:HESX1
gene id: 419612:HESX1
uniprot id: A0A8B7KC16
uniprot id: A0A8B8R818
uniprot id: A0A8B8RA60
uniprot id: A0A8B8RA65
uniprot id: A0A8B8RAV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

419612:TMEM132E
gene id: 419612:TMEM132E
uniprot id: A0A8B8R8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

419612:EMX2
gene id: 419612:EMX2
uniprot id: A0A8B7K940
names: Subcellular Location Annotation
messages: Nucleus

419612:UBE2B
gene id: 419612:UBE2B
uniprot id: A0A8B6YC40
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:LOC106730619
gene id: 419612:LOC106730619
uniprot id: A0A8B8SYA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

419612:CHRNB4
gene id: 419612:CHRNB4
uniprot id: A0A8B8S5F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:MYADM
gene id: 419612:MYADM
uniprot id: S9XPC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

419612:SPIRE1
gene id: 419612:SPIRE1
uniprot id: A0A8B8RYP9
uniprot id: A0A8B8S033
uniprot id: A0A8B8S0D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

419612:NIPAL3
gene id: 419612:NIPAL3
uniprot id: A0A8B7KF62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

419612:ASPHD1
gene id: 419612:ASPHD1
uniprot id: A0A8B8RI52
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

419612:PPFIA4
gene id: 419612:PPFIA4
uniprot id: A0A8B8RYN3
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

419612:AASDH
gene id: 419612:AASDH
uniprot id: A0A8B6Y979
uniprot id: A0A8B7K5A0
uniprot id: A0A8B8UH32
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

419612:BMT2
gene id: 419612:BMT2
uniprot id: A0A8B8TBH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

419612:TAF2
gene id: 419612:TAF2
uniprot id: A0A8B6YL19
uniprot id: A0A8B7KBD0
uniprot id: A0A8B7KD39
uniprot id: A0A8B8S2Y6
uniprot id: A0A8B8S306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

419612:LOC106730647
gene id: 419612:LOC106730647
uniprot id: A0A8B8S8A7
names: Similarity
messages: Belongs to the serpin family.

419612:EBF4
gene id: 419612:EBF4
uniprot id: A0A8B8RIT4
uniprot id: A0A8B8RIT5
uniprot id: A0A8B8RJ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

419612:CPLX2
gene id: 419612:CPLX2
uniprot id: A0A8B8RSL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

419612:POT1
gene id: 419612:POT1
uniprot id: A0A8B6YJC8
uniprot id: A0A8B8TB87
uniprot id: A0A8B8TBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

419612:KCNB2
gene id: 419612:KCNB2
uniprot id: A0A8B8S6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: dendrite

419612:GNB4
gene id: 419612:GNB4
uniprot id: A0A8B8TD77
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

419612:NELFCD
gene id: 419612:NELFCD
uniprot id: A0A8B8RHA9
uniprot id: A0A8B8RHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

419612:PARD6B
gene id: 419612:PARD6B
uniprot id: A0A8B8RHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

419612:NQO1
gene id: 419612:NQO1
uniprot id: A0A8B6YBQ4
uniprot id: A0A8B8TJW4
uniprot id: A0A8B8TL49
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

419612:DYSF
gene id: 419612:DYSF
uniprot id: A0A8B8UGH5
uniprot id: A0A8B8UGI1
uniprot id: A0A8B8UGI2
uniprot id: A0A8B8UGI8
uniprot id: A0A8B8UGJ2
uniprot id: A0A8B8UGJ3
uniprot id: A0A8B8UGJ6
uniprot id: A0A8B8UGJ8
uniprot id: A0A8B8UGK2
uniprot id: A0A8B8UGK3
uniprot id: A0A8B8UH57
uniprot id: A0A8B8UH61
uniprot id: A0A8B8UH62
uniprot id: A0A8B8UH66
uniprot id: A0A8B8UH67
uniprot id: A0A8B8UH71
uniprot id: A0A8B8UH73
uniprot id: A0A8B8UH76
uniprot id: A0A8B8UH80
uniprot id: A0A8B8UH81
uniprot id: A0A8B8UH85
uniprot id: A0A8B8UHV7
uniprot id: A0A8B8UHW2
uniprot id: A0A8B8UHW7
uniprot id: A0A8B8UHX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

419612:NAGK
gene id: 419612:NAGK
uniprot id: A0A8B8UH48
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

419612:ADGRG5
gene id: 419612:ADGRG5
uniprot id: A0A8B8TJ91
names: Subcellular Location Annotation
messages: Membrane

419612:TICAM1
gene id: 419612:TICAM1
uniprot id: A0A8B8RUW1
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer. Found in a multi-helicase-TICAM1 complex at least composed of DHX36, DDX1, DDX21 and TICAM1.
messages: Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines.
messages: Mitochondrion
messages: The N-terminal region is essential for activation of the IFNB promoter activity.
messages: autophagosome
messages: cytosol

419612:TMEM132A
gene id: 419612:TMEM132A
uniprot id: A0A8B8TT08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

419612:MAP7
gene id: 419612:MAP7
uniprot id: A0A8B6YK55
names: Similarity
messages: Belongs to the MAP7 family.

419612:PRPH
gene id: 419612:PRPH
uniprot id: A0A8B8U234
uniprot id: A0A8B8U2K9
uniprot id: A0A8B8U337
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: axon

419612:FAM98A
gene id: 419612:FAM98A
uniprot id: A0A8B6YMC9
names: Similarity
messages: Belongs to the FAM98 family.

419612:IL15
gene id: 419612:IL15
uniprot id: A0A8B6YNB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

419612:TNFRSF11A
gene id: 419612:TNFRSF11A
uniprot id: A0A8B8S7N0
uniprot id: A0A8B8S9U4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:IDI1
gene id: 419612:IDI1
uniprot id: A0A8B8SHE5
uniprot id: A0A8B8SIH2
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

419612:LOC102516568
gene id: 419612:LOC102516568
uniprot id: A0A8B6YKK6
names: Similarity
messages: Belongs to the cornifelin family.

419612:CD34
gene id: 419612:CD34
uniprot id: A0A8B6YBS5
uniprot id: A0A8B6YD45
names: Subcellular Location Annotation
messages: Membrane

419612:FAM135A
gene id: 419612:FAM135A
uniprot id: A0A8B8TDM3
uniprot id: A0A8B8TDM8
uniprot id: A0A8B8TDN1
uniprot id: A0A8B8TDN5
uniprot id: A0A8B8TDS8
uniprot id: A0A8B8TDT3
uniprot id: A0A8B8TEW8
names: Similarity
messages: Belongs to the FAM135 family.

419612:PTGFR
gene id: 419612:PTGFR
uniprot id: A0A8B8U8C0
uniprot id: A0A8B8U8I3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:NOL11
gene id: 419612:NOL11
uniprot id: A0A8B6YA60
names: Subcellular Location Annotation
messages: nucleolus

419612:GABRB3
gene id: 419612:GABRB3
uniprot id: A0A8B8S5X2
uniprot id: A0A8B8S647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:SOST
gene id: 419612:SOST
uniprot id: A0A8B8R810
names: Similarity
messages: Belongs to the sclerostin family.

419612:LOC102513122
gene id: 419612:LOC102513122
uniprot id: A0A8B6Y6M3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:C33H11orf87
gene id: 419612:C33H11orf87
uniprot id: A0A8B8SDN4
names: Subcellular Location Annotation
messages: Membrane

419612:NOX1
gene id: 419612:NOX1
uniprot id: A0A8B7KG07
uniprot id: A0A8B8SLL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

419612:INTS3
gene id: 419612:INTS3
uniprot id: A0A8B6Y8D7
names: Similarity
messages: Belongs to the Integrator subunit 3 family.

419612:PODXL
gene id: 419612:PODXL
uniprot id: A0A8B8TAG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the podocalyxin family.
messages: Cell membrane
messages: Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
messages: Membrane
messages: Membrane raft
messages: filopodium
messages: lamellipodium
messages: microvillus
messages: ruffle

419612:TCF7
gene id: 419612:TCF7
uniprot id: A0A8B8SR48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

419612:NSG1
gene id: 419612:NSG1
uniprot id: A0A8B8U658
uniprot id: A0A8B8U684
names: Similarity
messages: Belongs to the NSG family.

419612:LOC102520257
gene id: 419612:LOC102520257
uniprot id: A0A8B8TPQ7
uniprot id: A0A8B8TPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

419612:PTGR1
gene id: 419612:PTGR1
uniprot id: A0A8B6YAU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

419612:GNPDA1
gene id: 419612:GNPDA1
uniprot id: A0A8B8STQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

419612:LOC102508857
gene id: 419612:LOC102508857
uniprot id: A0A8B8TZD9
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:HSPB6
gene id: 419612:HSPB6
uniprot id: A0A8B8TP69
uniprot id: A0A8B8TPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Nucleus

419612:ADAM33
gene id: 419612:ADAM33
uniprot id: A0A8B8RIL1
uniprot id: A0A8B8RIL6
uniprot id: A0A8B8RIM1
uniprot id: A0A8B8RIM3
uniprot id: A0A8B8RIM7
uniprot id: A0A8B8RIM8
uniprot id: A0A8B8RIN4
uniprot id: A0A8B8RIP2
uniprot id: A0A8B8RIP7
uniprot id: A0A8B8RIS7
uniprot id: A0A8B8RIT3
uniprot id: A0A8B8RIT8
uniprot id: A0A8B8RIU3
uniprot id: A0A8B8RIV1
uniprot id: A0A8B8RIW8
uniprot id: A0A8B8RKG2
uniprot id: A0A8B8RKH2
uniprot id: A0A8B8RKH7
uniprot id: A0A8B8RKJ2
uniprot id: A0A8B8RKW2
uniprot id: A0A8B8RKW7
uniprot id: A0A8B8RKX3
uniprot id: A0A8B8RKX9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102509981
gene id: 419612:LOC102509981
uniprot id: A0A8B6YD19
uniprot id: A0A8B8TYB4
uniprot id: A0A8B8TZM7
names: Similarity
messages: Belongs to the neutral ceramidase family.

419612:PCSK4
gene id: 419612:PCSK4
uniprot id: A0A8B8RVK7
uniprot id: A0A8B8RVL1
uniprot id: A0A8B8RVL3
uniprot id: A0A8B8RWS5
uniprot id: A0A8B8RX49
uniprot id: A0A8B8RXF5
names: Similarity
messages: Belongs to the peptidase S8 family.

419612:ACBD5
gene id: 419612:ACBD5
uniprot id: A0A8B7KEU4
uniprot id: A0A8B8SIH8
uniprot id: A0A8B8SJK8
uniprot id: A0A8B8SJV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane
messages: Peroxisome membrane

419612:PRKG1
gene id: 419612:PRKG1
uniprot id: A0A8B6YCL9
uniprot id: A0A8B8TYD0
uniprot id: A0A8B8TZB8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

419612:ARPC4
gene id: 419612:ARPC4
uniprot id: A0A8B8RA48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

419612:UNC5D
gene id: 419612:UNC5D
uniprot id: A0A8B8S4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

419612:NPC1L1
gene id: 419612:NPC1L1
uniprot id: A0A8B6YAW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

419612:LOC106730222
gene id: 419612:LOC106730222
uniprot id: A0A8B8S2V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TSPAN9
gene id: 419612:TSPAN9
uniprot id: A0A8B8SIH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:LCNL1
gene id: 419612:LCNL1
uniprot id: A0A8B7K3M8
uniprot id: A0A8B8SY54
uniprot id: A0A8B8SYB4
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

419612:SMR3A
gene id: 419612:SMR3A
uniprot id: A0A8B8R9B5
names: Subcellular Location Annotation
messages: Secreted

419612:PHPT1
gene id: 419612:PHPT1
uniprot id: A0A8B8SYW5
names: Function
names: Similarity
messages: Belongs to the janus family.
messages: Exhibits phosphohistidine phosphatase activity.

419612:CDX4
gene id: 419612:CDX4
uniprot id: A0A8B6YSA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

419612:CHDH
gene id: 419612:CHDH
uniprot id: A0A8B8R839
uniprot id: A0A8B8R845
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

419612:TSHZ2
gene id: 419612:TSHZ2
uniprot id: A0A8B8RH54
uniprot id: A0A8B8RHC9
uniprot id: A0A8B8RJ22
uniprot id: A0A8B8RJ27
uniprot id: A0A8B8RJH4
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

419612:RNF168
gene id: 419612:RNF168
uniprot id: A0A8B6YG59
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF168 cannot initiate H2A 'Lys-63'-linked ubiquitination and is recruited following RNF8-dependent histone ubiquitination to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Monomer. Interacts with UBE2N/UBC13.
messages: Nucleus
messages: Sumoylated with SUMO1 by PIAS4 in response to double-strand breaks (DSBs).
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).
messages: Ubiquitinated.

419612:LOC106728686
gene id: 419612:LOC106728686
uniprot id: A0A8B8TWW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102520234
gene id: 419612:LOC102520234
uniprot id: A0A8B7KED2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

419612:DPF2
gene id: 419612:DPF2
uniprot id: A0A8B6YB57
names: Similarity
messages: Belongs to the requiem/DPF family.

419612:MTF2
gene id: 419612:MTF2
uniprot id: A0A8B6YKX5
uniprot id: A0A8B6YL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

419612:PDIK1L
gene id: 419612:PDIK1L
uniprot id: A0A8B8UAV4
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:UBR2
gene id: 419612:UBR2
uniprot id: A0A8B8RM20
uniprot id: A0A8B8RM23
uniprot id: A0A8B8RM25
uniprot id: A0A8B8RMC0
uniprot id: A0A8B8RMC7
uniprot id: A0A8B8RNT0
uniprot id: A0A8B8RP80
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

419612:TAS2R38
gene id: 419612:TAS2R38
uniprot id: S9WX76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

419612:PHLDA1
gene id: 419612:PHLDA1
uniprot id: A0A8B8U613
names: Subcellular Location Annotation
messages: Cytoplasm

419612:LYZL4
gene id: 419612:LYZL4
uniprot id: A0A8B6YCC6
uniprot id: A0A8B8RAN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

419612:LOC116659119
gene id: 419612:LOC116659119
uniprot id: A0A8B8RXH4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC116667611
gene id: 419612:LOC116667611
uniprot id: A0A8B8U3X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC116661868
gene id: 419612:LOC116661868
uniprot id: A0A8B8SK02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

419612:DCBLD1
gene id: 419612:DCBLD1
uniprot id: A0A8B8TEJ9
uniprot id: A0A8B8TEP9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MAPK1
gene id: 419612:MAPK1
uniprot id: A0A8B8SEF5
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: caveola
messages: focal adhesion

419612:CCZ1
gene id: 419612:CCZ1
uniprot id: A0A8B8RF89
names: Similarity
messages: Belongs to the CCZ1 family.

419612:LOC102522466
gene id: 419612:LOC102522466
uniprot id: A0A8B6YBL8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

419612:LOC102520741
gene id: 419612:LOC102520741
uniprot id: A0A8B8SLX2
names: Similarity
messages: Belongs to the GAGE family.

419612:ITGA1
gene id: 419612:ITGA1
uniprot id: A0A8B6YGG3
uniprot id: A0A8B8SC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

419612:FOXK1
gene id: 419612:FOXK1
uniprot id: A0A8B8RCY4
names: Subcellular Location Annotation
messages: Nucleus

419612:CNDP2
gene id: 419612:CNDP2
uniprot id: A0A8B8S993
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

419612:LOC102512073
gene id: 419612:LOC102512073
uniprot id: A0A8B8TGV7
uniprot id: A0A8B8TGW1
uniprot id: A0A8B8TI75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Belongs to the ferritin family.
messages: Membrane
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:TRMT13
gene id: 419612:TRMT13
uniprot id: A0A8B6YKY5
uniprot id: A0A8B8TLF5
uniprot id: A0A8B8TLT5
uniprot id: A0A8B8TMN1
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

419612:LOC102515720
gene id: 419612:LOC102515720
uniprot id: A0A8B6YL66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SLC30A8
gene id: 419612:SLC30A8
uniprot id: A0A8B8S0P9
uniprot id: A0A8B8S220
uniprot id: S9XX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

419612:GALNT5
gene id: 419612:GALNT5
uniprot id: A0A8B6YLP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

419612:SBDS
gene id: 419612:SBDS
uniprot id: A0A8B6YKZ9
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

419612:LOC102518127
gene id: 419612:LOC102518127
uniprot id: A0A8B7KCF6
uniprot id: A0A8B8TB18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:NCBP2
gene id: 419612:NCBP2
uniprot id: A0A8B6YBI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

419612:LOC102518010
gene id: 419612:LOC102518010
uniprot id: A0A8B8TRZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FAM3D
gene id: 419612:FAM3D
uniprot id: A0A8B6YFG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

419612:PSMB5
gene id: 419612:PSMB5
uniprot id: A0A8B6YBD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

419612:STMN3
gene id: 419612:STMN3
uniprot id: A0A8B8RHQ9
names: Similarity
messages: Belongs to the stathmin family.

419612:SEH1L
gene id: 419612:SEH1L
uniprot id: A0A8B8RZ90
uniprot id: A0A8B8RZA4
uniprot id: A0A8B8RZA8
uniprot id: A0A8B8S0L6
uniprot id: A0A8B8S0T1
uniprot id: A0A8B8S0W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

419612:LOC102510801
gene id: 419612:LOC102510801
uniprot id: A0A8B6Y8R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

419612:EGFL7
gene id: 419612:EGFL7
uniprot id: A0A8B8SXR3
uniprot id: A0A8B8SYJ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:PFKFB4
gene id: 419612:PFKFB4
uniprot id: A0A8B6YA13
uniprot id: A0A8B8R8Z4
uniprot id: A0A8B8RB50
uniprot id: A0A8B8RBS5
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

419612:LOC116660778
gene id: 419612:LOC116660778
uniprot id: A0A8B8S9B5
uniprot id: A0A8B8SBN4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:CHRM3
gene id: 419612:CHRM3
uniprot id: A0A8B8TZT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

419612:DNASE1L2
gene id: 419612:DNASE1L2
uniprot id: A0A8B8RDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

419612:PIGN
gene id: 419612:PIGN
uniprot id: A0A8B8S8T9
uniprot id: A0A8B8SA30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

419612:ANXA10
gene id: 419612:ANXA10
uniprot id: A0A8B8S980
uniprot id: A0A8B8SAH2
uniprot id: A0A8B8SAM5
names: Similarity
messages: Belongs to the annexin family.

419612:SGSH
gene id: 419612:SGSH
uniprot id: A0A8B8R680
names: Similarity
messages: Belongs to the sulfatase family.

419612:TSSK4
gene id: 419612:TSSK4
uniprot id: A0A8B8T6K1
uniprot id: A0A8B8T6R5
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:ROGDI
gene id: 419612:ROGDI
uniprot id: A0A8B8RDZ9
uniprot id: A0A8B8RG15
uniprot id: A0A8B8RGH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Presynapse
messages: Vesicle
messages: synaptic vesicle

419612:RPL39
gene id: 419612:RPL39
uniprot id: A0A8B7KAB6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

419612:CAVIN4
gene id: 419612:CAVIN4
uniprot id: A0A8B6YH33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

419612:LOC102514923
gene id: 419612:LOC102514923
uniprot id: A0A8B8UHT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CLIP1
gene id: 419612:CLIP1
uniprot id: A0A8B8SCJ5
names: Subcellular Location Annotation
messages: cytoskeleton

419612:GRWD1
gene id: 419612:GRWD1
uniprot id: A0A8B6YC05
names: Subcellular Location Annotation
messages: Nucleus

419612:CHAF1B
gene id: 419612:CHAF1B
uniprot id: A0A8B8S354
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102513052
gene id: 419612:LOC102513052
uniprot id: A0A8B7KEP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

419612:GTF2H3
gene id: 419612:GTF2H3
uniprot id: A0A8B6YDG7
uniprot id: A0A8B8SBM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

419612:LOC102515911
gene id: 419612:LOC102515911
uniprot id: A0A8B8U528
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

419612:TSN
gene id: 419612:TSN
uniprot id: A0A8B8SZ78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

419612:TNXB
gene id: 419612:TNXB
uniprot id: A0A8B8RKX8
uniprot id: A0A8B8RKY1
uniprot id: A0A8B8RKY4
uniprot id: A0A8B8RKY6
uniprot id: A0A8B8RKZ0
uniprot id: A0A8B8RKZ3
uniprot id: A0A8B8RL92
uniprot id: A0A8B8RL98
uniprot id: A0A8B8RMP4
uniprot id: A0A8B8RMQ1
uniprot id: A0A8B8RMQ8
uniprot id: A0A8B8RMR4
uniprot id: A0A8B8RN59
uniprot id: A0A8B8RN65
uniprot id: A0A8B8RN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

419612:TMEM86A
gene id: 419612:TMEM86A
uniprot id: A0A8B8TR79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

419612:ITPR1
gene id: 419612:ITPR1
uniprot id: A0A8B7KAL1
uniprot id: A0A8B7KCN7
uniprot id: A0A8B8R7H0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

419612:ELMO1
gene id: 419612:ELMO1
uniprot id: A0A8B6YN14
uniprot id: A0A8B8TBJ9
uniprot id: A0A8B8TBT9
uniprot id: A0A8B8TCM4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

419612:POLL
gene id: 419612:POLL
uniprot id: A0A8B7K8T7
uniprot id: A0A8B8TXB1
uniprot id: A0A8B8TYN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

419612:CCNG2
gene id: 419612:CCNG2
uniprot id: A0A8B8R7V9
names: Similarity
messages: Belongs to the cyclin family.

419612:BCOR
gene id: 419612:BCOR
uniprot id: A0A8B8SJZ0
names: Similarity
messages: Belongs to the BCOR family.

419612:ARF6
gene id: 419612:ARF6
uniprot id: S9WDJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

419612:PROS1
gene id: 419612:PROS1
uniprot id: A0A8B6YNC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:C9H19orf54
gene id: 419612:C9H19orf54
uniprot id: A0A8B6YJY0
uniprot id: A0A8B7KD97
uniprot id: A0A8B8TI40
uniprot id: A0A8B8TI42
uniprot id: A0A8B8TI51
names: Similarity
messages: Belongs to the ACTMAP family.

419612:ACAP2
gene id: 419612:ACAP2
uniprot id: A0A8B8T5W9
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

419612:FXYD2
gene id: 419612:FXYD2
uniprot id: A0A8B7K616
uniprot id: A0A8B8SE89
uniprot id: A0A8B8SFJ0
uniprot id: A0A8B8SGS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FXYD family.
messages: May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
messages: Membrane
messages: Regulatory subunit of the sodium/potassium-transporting ATPase which is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.

419612:ANXA11
gene id: 419612:ANXA11
uniprot id: A0A8B8TYU0
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

419612:LOC102518644
gene id: 419612:LOC102518644
uniprot id: A0A8B6YNH8
names: Similarity
messages: Belongs to the PRAME family.

419612:KRT34
gene id: 419612:KRT34
uniprot id: A0A8B8UHQ6
names: Similarity
messages: Belongs to the intermediate filament family.

419612:LOC102515332
gene id: 419612:LOC102515332
uniprot id: A0A8B8R4F0
uniprot id: A0A8B8R4M0
names: Subcellular Location Annotation
messages: Membrane

419612:LOC116666656
gene id: 419612:LOC116666656
uniprot id: A0A8B8TX15
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:NSG2
gene id: 419612:NSG2
uniprot id: A0A8B6YEM2
names: Similarity
messages: Belongs to the NSG family.

419612:GRIK1
gene id: 419612:GRIK1
uniprot id: A0A8B8SRZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

419612:LOC102514201
gene id: 419612:LOC102514201
uniprot id: A0A8B8U035
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ZRANB1
gene id: 419612:ZRANB1
uniprot id: A0A8B8TWA6
uniprot id: A0A8B8TXN2
names: Similarity
messages: Belongs to the peptidase C64 family.

419612:CALHM6
gene id: 419612:CALHM6
uniprot id: A0A8B8TGD8
uniprot id: A0A8B8THR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

419612:DNMT1
gene id: 419612:DNMT1
uniprot id: A0A8B7K6U8
uniprot id: A0A8B8RU55
uniprot id: A0A8B8RVQ6
uniprot id: A0A8B8RW11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

419612:ING4
gene id: 419612:ING4
uniprot id: A0A8B8SGB5
uniprot id: A0A8B8SGC0
uniprot id: A0A8B8SGC8
uniprot id: A0A8B8SGD3
uniprot id: A0A8B8SHG3
uniprot id: A0A8B8SHG9
uniprot id: A0A8B8SHJ4
uniprot id: A0A8B8SIX3
uniprot id: A0A8B8SIX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

419612:UNC5B
gene id: 419612:UNC5B
uniprot id: A0A8B8S754
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

419612:KCNQ4
gene id: 419612:KCNQ4
uniprot id: A0A8B8U5G5
uniprot id: A0A8B8U5H0
uniprot id: A0A8B8U5H1
uniprot id: A0A8B8U6D2
uniprot id: A0A8B8U6E0
uniprot id: A0A8B8U6E5
uniprot id: A0A8B8U6L6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:MEX3C
gene id: 419612:MEX3C
uniprot id: A0A8B7K913
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

419612:TCTEX1D1
gene id: 419612:TCTEX1D1
uniprot id: A0A8B6YPS8
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

419612:CAMK4
gene id: 419612:CAMK4
uniprot id: A0A8B6YMK7
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:USP4
gene id: 419612:USP4
uniprot id: A0A8B8R8U5
uniprot id: A0A8B8RAY8
uniprot id: A0A8B8RBM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

419612:SLAIN2
gene id: 419612:SLAIN2
uniprot id: A0A8B8UF98
uniprot id: A0A8B8UFA7
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

419612:GAST
gene id: 419612:GAST
uniprot id: S9XCX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
messages: Secreted

419612:URAD
gene id: 419612:URAD
uniprot id: A0A8B8UDA2
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

419612:BCHE
gene id: 419612:BCHE
uniprot id: A0A8B6YFT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

419612:SIN3B
gene id: 419612:SIN3B
uniprot id: A0A8B8RTF9
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC116658365
gene id: 419612:LOC116658365
uniprot id: A0A8B8RN83
names: Similarity
messages: Belongs to the TMA7 family.

419612:GNA15
gene id: 419612:GNA15
uniprot id: A0A8B8RVA3
uniprot id: A0A8B8RVA7
uniprot id: A0A8B8RWG0
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

419612:DHODH
gene id: 419612:DHODH
uniprot id: A0A8B6YIJ3
uniprot id: A0A8B8TJY1
uniprot id: A0A8B8TK83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

419612:MFN2
gene id: 419612:MFN2
uniprot id: A0A8B8U936
uniprot id: A0A8B8U9W5
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

419612:UBA6
gene id: 419612:UBA6
uniprot id: A0A8B8RAM6
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

419612:LOC116662082
gene id: 419612:LOC116662082
uniprot id: A0A8B8SNC0
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

419612:LOC102512467
gene id: 419612:LOC102512467
uniprot id: S9WQ05
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

419612:PICK1
gene id: 419612:PICK1
uniprot id: A0A8B8U0M1
uniprot id: A0A8B8U0Y9
uniprot id: A0A8B8U1M8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

419612:CSTF1
gene id: 419612:CSTF1
uniprot id: A0A8B7KCW8
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC116664745
gene id: 419612:LOC116664745
uniprot id: A0A8B8TAC8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:DEGS2
gene id: 419612:DEGS2
uniprot id: A0A8B8T8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:RAB3D
gene id: 419612:RAB3D
uniprot id: T0NL88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

419612:LY6G5C
gene id: 419612:LY6G5C
uniprot id: A0A8B8RN93
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Forms oligomers.
messages: May have a role in hematopoietic cell differentiation.
messages: Secreted

419612:LOC102522281
gene id: 419612:LOC102522281
uniprot id: A0A8B6YAB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102509712
gene id: 419612:LOC102509712
uniprot id: A0A8B8R3R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

419612:LOC102517094
gene id: 419612:LOC102517094
uniprot id: A0A8B6YRU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:OPTC
gene id: 419612:OPTC
uniprot id: A0A8B8RYR5
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

419612:PSD3
gene id: 419612:PSD3
uniprot id: A0A8B8S3X7
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

419612:FAM3B
gene id: 419612:FAM3B
uniprot id: A0A8B8RJU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

419612:MED18
gene id: 419612:MED18
uniprot id: A0A8B7KAY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

419612:FAM227A
gene id: 419612:FAM227A
uniprot id: A0A8B8U1R8
names: Similarity
messages: Belongs to the FAM227 family.

419612:GAS8
gene id: 419612:GAS8
uniprot id: A0A8B8RTB7
uniprot id: A0A8B8RTN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum
messages: flagellum axoneme

419612:NIP7
gene id: 419612:NIP7
uniprot id: A0A8B7K753
uniprot id: S9X993
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

419612:LOC116660661
gene id: 419612:LOC116660661
uniprot id: A0A8B8S9S8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:OST4
gene id: 419612:OST4
uniprot id: A0A8B6YK24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:STX3
gene id: 419612:STX3
uniprot id: A0A8B8TSZ8
uniprot id: A0A8B8TU00
uniprot id: A0A8B8TU23
names: Similarity
messages: Belongs to the syntaxin family.

419612:NKG7
gene id: 419612:NKG7
uniprot id: A0A8B8TNM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

419612:ARF5
gene id: 419612:ARF5
uniprot id: A0A8B8TBD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

419612:LOC102512567
gene id: 419612:LOC102512567
uniprot id: A0A8B6YLI7
names: Similarity
messages: Belongs to the KHDC1 family.

419612:ETNPPL
gene id: 419612:ETNPPL
uniprot id: A0A8B8RHQ7
uniprot id: A0A8B8RJL7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

419612:LHX1
gene id: 419612:LHX1
uniprot id: A0A8B8UJA7
names: Subcellular Location Annotation
messages: Nucleus

419612:INO80D
gene id: 419612:INO80D
uniprot id: A0A8B8T0W0
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102514493
gene id: 419612:LOC102514493
uniprot id: A0A8B6Y5E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102524012
gene id: 419612:LOC102524012
uniprot id: A0A8B6YED1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102507722
gene id: 419612:LOC102507722
uniprot id: A0A8B8SH86
names: Similarity
messages: Belongs to the Rho GDI family.

419612:TBX10
gene id: 419612:TBX10
uniprot id: A0A8B6YL25
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

419612:MMAA
gene id: 419612:MMAA
uniprot id: A0A8B6YJ13
uniprot id: A0A8B8RQJ2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

419612:GABARAP
gene id: 419612:GABARAP
uniprot id: A0A8B6Y7P4
names: Similarity
messages: Belongs to the ATG8 family.

419612:GHITM
gene id: 419612:GHITM
uniprot id: A0A8B6Y7I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

419612:CNTN1
gene id: 419612:CNTN1
uniprot id: A0A8B6YPY5
uniprot id: A0A8B8U4C3
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

419612:LOC102515207
gene id: 419612:LOC102515207
uniprot id: A0A8B6YMP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FLT1
gene id: 419612:FLT1
uniprot id: A0A8B8UD56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

419612:UBE2G2
gene id: 419612:UBE2G2
uniprot id: A0A8B8TYQ6
uniprot id: A0A8B8TYV0
uniprot id: A0A8B8TZ61
uniprot id: A0A8B8TZ84
uniprot id: A0A8B8TZS5
uniprot id: A0A8B8U0Q4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:DEFB110
gene id: 419612:DEFB110
uniprot id: A0A8B6YL05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

419612:PTPRF
gene id: 419612:PTPRF
uniprot id: A0A8B8U5R3
uniprot id: A0A8B8U5R7
uniprot id: A0A8B8U5R8
uniprot id: A0A8B8U5S2
uniprot id: A0A8B8U5S4
uniprot id: A0A8B8U5S8
uniprot id: A0A8B8U6N6
uniprot id: A0A8B8U6P0
uniprot id: A0A8B8U6P1
uniprot id: A0A8B8U6P5
uniprot id: A0A8B8U6Q0
uniprot id: A0A8B8U6V7
uniprot id: A0A8B8U6W2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

419612:TET1
gene id: 419612:TET1
uniprot id: A0A8B8TYM8
uniprot id: A0A8B8TZN6
uniprot id: A0A8B8TZZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

419612:IKBKE
gene id: 419612:IKBKE
uniprot id: A0A8B8RYC0
uniprot id: A0A8B8RZQ6
names: Subcellular Location Annotation
messages: Cytoplasm

419612:LOC102508103
gene id: 419612:LOC102508103
uniprot id: A0A8B6YAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PSMC5
gene id: 419612:PSMC5
uniprot id: A0A8B8R4S7
uniprot id: A0A8B8R7H1
names: Similarity
messages: Belongs to the AAA ATPase family.

419612:DHRS7C
gene id: 419612:DHRS7C
uniprot id: A0A8B6Y9S7
uniprot id: A0A8B7K572
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:LOC102507188
gene id: 419612:LOC102507188
uniprot id: A0A8B8SSD8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

419612:NMUR2
gene id: 419612:NMUR2
uniprot id: A0A8B6YIY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

419612:CUL1
gene id: 419612:CUL1
uniprot id: A0A8B8TAD3
names: Similarity
messages: Belongs to the cullin family.

419612:SUPT6H
gene id: 419612:SUPT6H
uniprot id: A0A8B7KC26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

419612:CDK20
gene id: 419612:CDK20
uniprot id: A0A8B8S9Q3
uniprot id: A0A8B8SAY1
uniprot id: A0A8B8SB34
uniprot id: S9XFB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: cilium

419612:CDH26
gene id: 419612:CDH26
uniprot id: A0A8B8RJU3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:AVPR2
gene id: 419612:AVPR2
uniprot id: A0A8B8SKL7
uniprot id: A0A8B8SLQ3
uniprot id: A0A8B8SM13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:GPN2
gene id: 419612:GPN2
uniprot id: A0A8B6Y6E6
uniprot id: A0A8B8UA81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

419612:ADAMTS14
gene id: 419612:ADAMTS14
uniprot id: A0A8B8S774
uniprot id: A0A8B8S778
uniprot id: A0A8B8S780
uniprot id: A0A8B8S784
uniprot id: A0A8B8S8I1
uniprot id: A0A8B8S8P2
uniprot id: A0A8B8S9E7
uniprot id: A0A8B8S9F1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:MOXD1
gene id: 419612:MOXD1
uniprot id: A0A8B8TF15
uniprot id: A0A8B8TF57
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

419612:ZNF326
gene id: 419612:ZNF326
uniprot id: A0A8B8TL10
uniprot id: A0A8B8TL11
uniprot id: A0A8B8TLC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AKAP95 family.
messages: Nucleus matrix

419612:MALRD1
gene id: 419612:MALRD1
uniprot id: A0A8B8SKZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:GTF2I
gene id: 419612:GTF2I
uniprot id: A0A8B8RBN6
uniprot id: A0A8B8RBP0
uniprot id: A0A8B8RBP1
uniprot id: A0A8B8RBP3
uniprot id: A0A8B8RDS4
uniprot id: A0A8B8REA4
uniprot id: A0A8B8REA9
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102509398
gene id: 419612:LOC102509398
uniprot id: A0A8B8U8Z4
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

419612:ELAVL2
gene id: 419612:ELAVL2
uniprot id: A0A8B7KEN8
uniprot id: A0A8B7KGM2
uniprot id: A0A8B8STP7
uniprot id: A0A8B8SU67
uniprot id: A0A8B8SU72
uniprot id: A0A8B8SUK8
names: Similarity
messages: Belongs to the RRM elav family.

419612:PRPF4B
gene id: 419612:PRPF4B
uniprot id: A0A8B8RK43
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

419612:SPIC
gene id: 419612:SPIC
uniprot id: A0A8B6YKL8
uniprot id: A0A8B8U4A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:SLCO2B1
gene id: 419612:SLCO2B1
uniprot id: A0A8B7K859
uniprot id: A0A8B7K8C4
uniprot id: A0A8B8TSN1
uniprot id: A0A8B8TTK4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:ZC3HAV1
gene id: 419612:ZC3HAV1
uniprot id: A0A8B8TBW6
names: Similarity
messages: Belongs to the ARTD/PARP family.

419612:SPATA6
gene id: 419612:SPATA6
uniprot id: A0A8B6Y9L0
uniprot id: A0A8B6Y9U2
uniprot id: A0A8B8U6A6
uniprot id: A0A8B8U777
uniprot id: A0A8B8U7D6
names: Similarity
messages: Belongs to the SPATA6 family.

419612:SPON1
gene id: 419612:SPON1
uniprot id: A0A8B7KES9
uniprot id: A0A8B8TSJ9
names: Subcellular Location Annotation
messages: extracellular matrix

419612:ZDHHC4
gene id: 419612:ZDHHC4
uniprot id: A0A8B6Y9R5
uniprot id: A0A8B7KBT0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

419612:LOC102518541
gene id: 419612:LOC102518541
uniprot id: A0A8B7K733
names: Subcellular Location Annotation
messages: Membrane

419612:USP11
gene id: 419612:USP11
uniprot id: A0A8B8SNC6
uniprot id: A0A8B8SNC7
uniprot id: A0A8B8SPA7
uniprot id: A0A8B8SQI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

419612:STX12
gene id: 419612:STX12
uniprot id: A0A8B8UB26
names: Similarity
messages: Belongs to the syntaxin family.

419612:TMEM170B
gene id: 419612:TMEM170B
uniprot id: A0A8B8RKB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

419612:CNOT8
gene id: 419612:CNOT8
uniprot id: S9W9F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

419612:SIX5
gene id: 419612:SIX5
uniprot id: A0A8B8THE0
names: Subcellular Location Annotation
messages: Nucleus

419612:RAD21L1
gene id: 419612:RAD21L1
uniprot id: A0A8B8RIV4
uniprot id: A0A8B8RKP5
uniprot id: A0A8B8RL51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

419612:HK1
gene id: 419612:HK1
uniprot id: A0A8B8TYP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

419612:WDR44
gene id: 419612:WDR44
uniprot id: A0A8B8SMN2
names: Subcellular Location Annotation
messages: trans-Golgi network

419612:CFAP298
gene id: 419612:CFAP298
uniprot id: A0A8B8SN82
uniprot id: A0A8B8SPC1
uniprot id: A0A8B8SPD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

419612:PRKAR1A
gene id: 419612:PRKAR1A
uniprot id: A0A8B8R4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

419612:SNTG2
gene id: 419612:SNTG2
uniprot id: A0A8B8UI99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

419612:CCL11
gene id: 419612:CCL11
uniprot id: A0A8B6YCR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

419612:LOC102503506
gene id: 419612:LOC102503506
uniprot id: A0A8B8SHD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

419612:PDIA3
gene id: 419612:PDIA3
uniprot id: A0A8B7K6F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

419612:CD4
gene id: 419612:CD4
uniprot id: A0A8B8SHL5
names: Subcellular Location Annotation
messages: Cell membrane

419612:ZDHHC13
gene id: 419612:ZDHHC13
uniprot id: A0A8B6YSX8
uniprot id: A0A8B8TR72
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

419612:CALHM5
gene id: 419612:CALHM5
uniprot id: A0A8B6YRG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

419612:CALB1
gene id: 419612:CALB1
uniprot id: A0A8B6YIU8
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.

419612:LDLRAD1
gene id: 419612:LDLRAD1
uniprot id: A0A8B7K7D3
uniprot id: A0A8B8U7G9
uniprot id: A0A8B8U7I9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:FOXR2
gene id: 419612:FOXR2
uniprot id: A0A8B6YMQ9
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102518117
gene id: 419612:LOC102518117
uniprot id: A0A8B6YDY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ROPN1L
gene id: 419612:ROPN1L
uniprot id: A0A8B8S6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

419612:MFSD6
gene id: 419612:MFSD6
uniprot id: A0A8B8T1J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

419612:LOC102524575
gene id: 419612:LOC102524575
uniprot id: S9XBN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ALDH16A1
gene id: 419612:ALDH16A1
uniprot id: A0A8B6Y654
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Interacts with SPG21.

419612:GPR87
gene id: 419612:GPR87
uniprot id: A0A8B6YJE0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:ST6GALNAC6
gene id: 419612:ST6GALNAC6
uniprot id: A0A8B7K804
uniprot id: A0A8B7KA65
uniprot id: A0A8B8SWM9
uniprot id: A0A8B8SWR8
uniprot id: A0A8B8SX42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

419612:CNKSR1
gene id: 419612:CNKSR1
uniprot id: A0A8B8UA33
names: Similarity
messages: Belongs to the CNKSR family.

419612:LOC102522622
gene id: 419612:LOC102522622
uniprot id: S9WE77
names: Similarity
messages: Belongs to the CD225/Dispanin family.

419612:RXRA
gene id: 419612:RXRA
uniprot id: A0A8B8SXI7
uniprot id: A0A8B8SXY2
uniprot id: A0A8B8SYQ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

419612:LOC116667829
gene id: 419612:LOC116667829
uniprot id: A0A8B8U598
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MRPL15
gene id: 419612:MRPL15
uniprot id: S9XME9
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

419612:LOC106729844
gene id: 419612:LOC106729844
uniprot id: A0A8B7KB14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

419612:ETV1
gene id: 419612:ETV1
uniprot id: A0A8B7KD41
uniprot id: A0A8B7KF79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:LOC102513377
gene id: 419612:LOC102513377
uniprot id: A0A8B7KFT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MPV17L
gene id: 419612:MPV17L
uniprot id: A0A8B8RHW7
uniprot id: A0A8B8RIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

419612:HCN1
gene id: 419612:HCN1
uniprot id: A0A8B8SBX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

419612:RPS23
gene id: 419612:RPS23
uniprot id: A0A8B6YJ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Rough endoplasmic reticulum

419612:GPR161
gene id: 419612:GPR161
uniprot id: A0A8B8RP21
uniprot id: A0A8B8RP24
uniprot id: S9XQA8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:BSX
gene id: 419612:BSX
uniprot id: A0A8B8SEB7
names: Subcellular Location Annotation
messages: Nucleus

419612:STX16
gene id: 419612:STX16
uniprot id: A0A8B6YGQ1
uniprot id: A0A8B6YGQ3
uniprot id: A0A8B6YH17
uniprot id: A0A8B6YHY5
uniprot id: A0A8B8RH94
names: Similarity
messages: Belongs to the syntaxin family.

419612:DPPA2
gene id: 419612:DPPA2
uniprot id: A0A8B8RXI2
uniprot id: A0A8B8RYX9
names: Subcellular Location Annotation
messages: Nucleus

419612:PSMG1
gene id: 419612:PSMG1
uniprot id: A0A8B8RRS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PSMG1 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
messages: Cytoplasm
messages: Forms a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer interacts directly with the PSMA5 and PSMA7 proteasome alpha subunits.
messages: Forms a heterodimer with psmg2.

419612:GSR
gene id: 419612:GSR
uniprot id: A0A8B7KG85
uniprot id: A0A8B8S537
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

419612:RRM2B
gene id: 419612:RRM2B
uniprot id: A0A8B7KF54
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

419612:LOC106730240
gene id: 419612:LOC106730240
uniprot id: A0A8B8TR47
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

419612:LOC102518649
gene id: 419612:LOC102518649
uniprot id: A0A8B8SMA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

419612:GLB1L
gene id: 419612:GLB1L
uniprot id: A0A8B7KC89
uniprot id: A0A8B7KDE1
uniprot id: A0A8B8T1M8
uniprot id: A0A8B8T283
uniprot id: A0A8B8T2I5
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

419612:ATP6V1B1
gene id: 419612:ATP6V1B1
uniprot id: A0A8B8UGG1
uniprot id: A0A8B8UH39
uniprot id: A0A8B8UH43
uniprot id: A0A8B8UHT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

419612:CLDN25
gene id: 419612:CLDN25
uniprot id: S9YH08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

419612:HNF4A
gene id: 419612:HNF4A
uniprot id: A0A8B6YN22
uniprot id: A0A8B6YN91
uniprot id: A0A8B7KFK3
uniprot id: A0A8B7KHQ9
uniprot id: A0A8B8RGL5
uniprot id: A0A8B8RGL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

419612:GRK6
gene id: 419612:GRK6
uniprot id: A0A8B8RSE2
uniprot id: A0A8B8RSF4
uniprot id: A0A8B8RT91
uniprot id: A0A8B8RT97
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

419612:KRT15
gene id: 419612:KRT15
uniprot id: A0A8B6YBA6
uniprot id: A0A8B8UHJ9
names: Similarity
messages: Belongs to the intermediate filament family.

419612:GBA
gene id: 419612:GBA
uniprot id: A0A8B6Y5M1
uniprot id: A0A8B7K3E1
uniprot id: A0A8B8RRZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

419612:LOC102507166
gene id: 419612:LOC102507166
uniprot id: A0A8B6YEN7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TACR3
gene id: 419612:TACR3
uniprot id: A0A8B7KDS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:SLC25A43
gene id: 419612:SLC25A43
uniprot id: A0A8B8SNQ4
uniprot id: A0A8B8SNR5
uniprot id: A0A8B8SPZ5
uniprot id: A0A8B8SQV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:LOC102522811
gene id: 419612:LOC102522811
uniprot id: A0A8B6YDF1
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:PTX3
gene id: 419612:PTX3
uniprot id: A0A8B8TH28
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:HS6ST1
gene id: 419612:HS6ST1
uniprot id: A0A8B8SZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

419612:BORCS5
gene id: 419612:BORCS5
uniprot id: A0A8B8SFL4
uniprot id: A0A8B8SFL8
uniprot id: A0A8B8SGR2
uniprot id: A0A8B8SGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

419612:SLC5A11
gene id: 419612:SLC5A11
uniprot id: A0A8B8RHG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

419612:KIF12
gene id: 419612:KIF12
uniprot id: A0A8B8SVP4
uniprot id: A0A8B8SVZ3
uniprot id: A0A8B8SWE7
uniprot id: A0A8B8SX24
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:POU3F2
gene id: 419612:POU3F2
uniprot id: A0A8B8TDJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

419612:RAX
gene id: 419612:RAX
uniprot id: A0A8B8S8A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

419612:CHD9
gene id: 419612:CHD9
uniprot id: A0A8B6YKI9
uniprot id: A0A8B8TIY9
uniprot id: A0A8B8TIZ4
uniprot id: A0A8B8TIZ5
uniprot id: A0A8B8TJ00
uniprot id: A0A8B8TJ06
uniprot id: A0A8B8TJ13
uniprot id: A0A8B8TJ42
uniprot id: A0A8B8TJ51
uniprot id: A0A8B8TJ56
uniprot id: A0A8B8TK68
uniprot id: A0A8B8TK74
uniprot id: A0A8B8TK81
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

419612:ZNF445
gene id: 419612:ZNF445
uniprot id: A0A8B8RAE4
names: Subcellular Location Annotation
messages: Nucleus

419612:KIF5C
gene id: 419612:KIF5C
uniprot id: A0A8B8T059
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:ATG12
gene id: 419612:ATG12
uniprot id: A0A8B6YMX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Ubiquitin-like protein involved in autophagic vesicle formation.

419612:NTNG2
gene id: 419612:NTNG2
uniprot id: A0A8B8SX22
uniprot id: A0A8B8SX85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:GNG11
gene id: 419612:GNG11
uniprot id: S9XK08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

419612:POLR2H
gene id: 419612:POLR2H
uniprot id: A0A8B6YI60
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

419612:CCSER1
gene id: 419612:CCSER1
uniprot id: A0A8B8RC90
uniprot id: A0A8B8RCC5
uniprot id: A0A8B8RCD0
uniprot id: A0A8B8RCD5
uniprot id: A0A8B8REG4
names: Similarity
messages: Belongs to the CCSER family.

419612:LOC102508377
gene id: 419612:LOC102508377
uniprot id: S9WXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:STON2
gene id: 419612:STON2
uniprot id: A0A8B8T7X6
uniprot id: A0A8B8T8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm

419612:TRIM54
gene id: 419612:TRIM54
uniprot id: A0A8B6YNQ3
uniprot id: A0A8B8UGB4
names: Function
names: Subcellular Location Annotation
messages: May bind and stabilize microtubules during myotubes formation.
messages: Z line

419612:TSPYL6
gene id: 419612:TSPYL6
uniprot id: S9YXK8
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

419612:CALHM4
gene id: 419612:CALHM4
uniprot id: A0A8B8TFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

419612:PBX2
gene id: 419612:PBX2
uniprot id: A0A8B6YAH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

419612:C2H4orf48
gene id: 419612:C2H4orf48
uniprot id: A0A8B8U2M3
names: Subcellular Location Annotation
messages: Secreted

419612:TSR2
gene id: 419612:TSR2
uniprot id: A0A8B6YNZ5
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

419612:GPR15
gene id: 419612:GPR15
uniprot id: A0A8B6YCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:BBS2
gene id: 419612:BBS2
uniprot id: A0A8B6YKE6
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

419612:EXOC2
gene id: 419612:EXOC2
uniprot id: A0A8B8RJY8
uniprot id: A0A8B8RLS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

419612:SLC25A12
gene id: 419612:SLC25A12
uniprot id: A0A8B6YPP1
uniprot id: A0A8B7KHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

419612:LOC102515767
gene id: 419612:LOC102515767
uniprot id: A0A8B6YC50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CUL2
gene id: 419612:CUL2
uniprot id: A0A8B8SI87
uniprot id: A0A8B8SKQ1
names: Similarity
messages: Belongs to the cullin family.

419612:MBOAT2
gene id: 419612:MBOAT2
uniprot id: A0A8B8UE63
uniprot id: A0A8B8UE65
uniprot id: A0A8B8UEY9
names: Subcellular Location Annotation
messages: Membrane

419612:LOC106730534
gene id: 419612:LOC106730534
uniprot id: A0A8B8RN63
uniprot id: A0A8B8RN64
uniprot id: A0A8B8RNJ2
uniprot id: A0A8B8RPV6
names: Similarity
messages: Belongs to the MHC class I family.

419612:TRPV6
gene id: 419612:TRPV6
uniprot id: A0A8B6YH69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:CTNND2
gene id: 419612:CTNND2
uniprot id: A0A8B8S893
uniprot id: A0A8B8S8D6
names: Similarity
messages: Belongs to the beta-catenin family.

419612:MUC5B
gene id: 419612:MUC5B
uniprot id: A0A8B8TV24
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:AKT3
gene id: 419612:AKT3
uniprot id: A0A8B8RWU6
uniprot id: A0A8B8RWV2
uniprot id: A0A8B8RWV3
uniprot id: A0A8B8RY51
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

419612:SEPTIN11
gene id: 419612:SEPTIN11
uniprot id: A0A8B8R5S7
uniprot id: A0A8B8R7Y3
uniprot id: A0A8B8R8I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

419612:FAM160B1
gene id: 419612:FAM160B1
uniprot id: A0A8B8TY55
names: Similarity
messages: Belongs to the FHIP family.

419612:IRX1
gene id: 419612:IRX1
uniprot id: A0A8B8S5S0
uniprot id: A0A8B8S5S5
uniprot id: A0A8B8S7T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

419612:THBS1
gene id: 419612:THBS1
uniprot id: A0A8B6YC26
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:GABRB1
gene id: 419612:GABRB1
uniprot id: A0A8B8UFD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:SLC6A5
gene id: 419612:SLC6A5
uniprot id: A0A8B8TS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

419612:HCK
gene id: 419612:HCK
uniprot id: A0A8B6YAD9
uniprot id: A0A8B7K6A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

419612:CENPX
gene id: 419612:CENPX
uniprot id: A0A8B8R5C3
uniprot id: A0A8B8R5R5
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

419612:CTSC
gene id: 419612:CTSC
uniprot id: A0A8B6YQZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Lysosome
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

419612:LOC106729886
gene id: 419612:LOC106729886
uniprot id: A0A8B8TGS2
uniprot id: A0A8B8TGS4
names: Subcellular Location Annotation
messages: Membrane

419612:TMED7
gene id: 419612:TMED7
uniprot id: A0A8B7KFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

419612:SESN2
gene id: 419612:SESN2
uniprot id: A0A8B6Y6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

419612:CDH24
gene id: 419612:CDH24
uniprot id: A0A8B8T6K2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

419612:NDP
gene id: 419612:NDP
uniprot id: A0A8B6YMZ3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

419612:LOC102518693
gene id: 419612:LOC102518693
uniprot id: A0A8B8S4S4
names: Similarity
messages: Belongs to the SUI1 family.

419612:IFT57
gene id: 419612:IFT57
uniprot id: A0A8B8SX26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

419612:CDC42EP4
gene id: 419612:CDC42EP4
uniprot id: A0A8B8R492
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

419612:PIK3R2
gene id: 419612:PIK3R2
uniprot id: A0A8B8RU44
uniprot id: A0A8B8RV37
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

419612:FGD5
gene id: 419612:FGD5
uniprot id: A0A8B8RBH7
names: Subcellular Location Annotation
messages: cytoskeleton

419612:LOC102505795
gene id: 419612:LOC102505795
uniprot id: S9X567
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

419612:CTLA4
gene id: 419612:CTLA4
uniprot id: A0A8B6YNN3
uniprot id: A0A8B6YNV8
uniprot id: A0A8B8T0X0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

419612:MED15
gene id: 419612:MED15
uniprot id: A0A8B8SDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

419612:MCCC2
gene id: 419612:MCCC2
uniprot id: A0A8B6YH23
names: Similarity
messages: Belongs to the AccD/PCCB family.

419612:HOXB8
gene id: 419612:HOXB8
uniprot id: A0A8B8R6W1
uniprot id: A0A8B8R913
names: Subcellular Location Annotation
messages: Nucleus

419612:PARP16
gene id: 419612:PARP16
uniprot id: A0A8B6YIT1
uniprot id: A0A8B8T3I1
uniprot id: A0A8B8T3I2
uniprot id: A0A8B8T499
names: Similarity
messages: Belongs to the ARTD/PARP family.

419612:ACTG2
gene id: 419612:ACTG2
uniprot id: A0A8B7K415
names: Similarity
messages: Belongs to the actin family.

419612:CRYBG3
gene id: 419612:CRYBG3
uniprot id: A0A8B8TTR2
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

419612:FEN1
gene id: 419612:FEN1
uniprot id: S9XGF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Mitochondrion
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

419612:AKIRIN2
gene id: 419612:AKIRIN2
uniprot id: A0A8B8TE05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

419612:SCN4A
gene id: 419612:SCN4A
uniprot id: A0A8B8R4X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

419612:TSPAN2
gene id: 419612:TSPAN2
uniprot id: A0A8B8TL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:TGFB1
gene id: 419612:TGFB1
uniprot id: A0A8B8TI15
uniprot id: A0A8B8TI41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with LRRC33/NRROS regulates activation of TGF-beta-1 in macrophages and microglia. Interaction with LRRC32/GARP controls activation of TGF-beta-1 on the surface of activated regulatory T-cells (Tregs). Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

419612:MAST2
gene id: 419612:MAST2
uniprot id: A0A8B8U645
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

419612:LOC102512748
gene id: 419612:LOC102512748
uniprot id: A0A8B6YQ31
uniprot id: A0A8B8SKU8
uniprot id: A0A8B8SM95
names: Similarity
messages: Belongs to the SNF7 family.

419612:LOC102519496
gene id: 419612:LOC102519496
uniprot id: A0A8B6YJ72
uniprot id: A0A8B8RC23
uniprot id: A0A8B8RC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

419612:SLC30A7
gene id: 419612:SLC30A7
uniprot id: A0A8B6YMG5
uniprot id: A0A8B8TLV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Membrane
messages: trans-Golgi network membrane

419612:GLDN
gene id: 419612:GLDN
uniprot id: A0A8B8T511
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:TMEM91
gene id: 419612:TMEM91
uniprot id: A0A8B8TI25
uniprot id: A0A8B8TI27
names: Similarity
messages: Belongs to the CD225/Dispanin family.

419612:AKIRIN1
gene id: 419612:AKIRIN1
uniprot id: A0A8B8U675
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

419612:CCNF
gene id: 419612:CCNF
uniprot id: A0A8B8RFR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family.
messages: Nucleus
messages: centriole
messages: perinuclear region

419612:GALNT1
gene id: 419612:GALNT1
uniprot id: A0A8B8S0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

419612:RPL10L
gene id: 419612:RPL10L
uniprot id: S9WG52
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

419612:RHBDL2
gene id: 419612:RHBDL2
uniprot id: A0A8B7KBA5
uniprot id: A0A8B8U671
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Membrane

419612:CENPK
gene id: 419612:CENPK
uniprot id: A0A8B8SGR6
uniprot id: A0A8B8SI81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

419612:EIF1
gene id: 419612:EIF1
uniprot id: A0A8B6YA23
names: Similarity
messages: Belongs to the SUI1 family.

419612:RAB14
gene id: 419612:RAB14
uniprot id: A0A8B8SWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

419612:HDAC7
gene id: 419612:HDAC7
uniprot id: A0A8B8U1W3
uniprot id: A0A8B8U1W7
uniprot id: A0A8B8U1W8
uniprot id: A0A8B8U1X2
uniprot id: A0A8B8U1X3
uniprot id: A0A8B8U2D5
uniprot id: A0A8B8U2D9
uniprot id: A0A8B8U2E4
uniprot id: A0A8B8U2E9
uniprot id: A0A8B8U2W6
uniprot id: A0A8B8U2X1
uniprot id: A0A8B8U2X5
uniprot id: A0A8B8U351
uniprot id: A0A8B8U356
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

419612:LOC102507048
gene id: 419612:LOC102507048
uniprot id: A0A8B6YR88
names: Similarity
messages: Belongs to the intermediate filament family.

419612:ADCK2
gene id: 419612:ADCK2
uniprot id: A0A8B6YFX9
uniprot id: A0A8B7KAQ6
uniprot id: A0A8B8TAW9
uniprot id: A0A8B8TAX3
uniprot id: A0A8B8TB16
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

419612:LOC102510919
gene id: 419612:LOC102510919
uniprot id: A0A8B8UJM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

419612:LOC116662707
gene id: 419612:LOC116662707
uniprot id: A0A8B8SRX9
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:SLF2
gene id: 419612:SLF2
uniprot id: A0A8B6YDS6
names: Similarity
messages: Belongs to the FAM178 family.

419612:ENTR1
gene id: 419612:ENTR1
uniprot id: A0A8B8SXY3
names: Similarity
messages: Belongs to the ENTR1 family.

419612:LOC102511190
gene id: 419612:LOC102511190
uniprot id: A0A8B6YNF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

419612:NOSIP
gene id: 419612:NOSIP
uniprot id: A0A8B8TGP4
uniprot id: A0A8B8TGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
messages: Nucleus

419612:ISYNA1
gene id: 419612:ISYNA1
uniprot id: A0A8B8RT47
uniprot id: A0A8B8RV24
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

419612:LOC102520525
gene id: 419612:LOC102520525
uniprot id: A0A8B8SFJ6
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

419612:BPNT1
gene id: 419612:BPNT1
uniprot id: A0A8B7KCF5
uniprot id: T0MH88
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

419612:XPR1
gene id: 419612:XPR1
uniprot id: A0A8B8RQ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

419612:SLC66A3
gene id: 419612:SLC66A3
uniprot id: A0A8B8UEC0
uniprot id: A0A8B8UFR5
names: Subcellular Location Annotation
messages: Membrane

419612:APOM
gene id: 419612:APOM
uniprot id: A0A8B7K610
uniprot id: S9YN35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted

419612:CXCL16
gene id: 419612:CXCL16
uniprot id: A0A8B7K7D9
names: Subcellular Location Annotation
messages: Membrane

419612:LOC116661791
gene id: 419612:LOC116661791
uniprot id: A0A8B8SJ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:GPBP1
gene id: 419612:GPBP1
uniprot id: A0A8B6YBE8
uniprot id: A0A8B7K980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

419612:STAB1
gene id: 419612:STAB1
uniprot id: A0A8B6YF71
uniprot id: A0A8B8R8A7
uniprot id: A0A8B8R8B0
uniprot id: A0A8B8R8F7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:TUBGCP2
gene id: 419612:TUBGCP2
uniprot id: A0A8B8TW16
uniprot id: A0A8B8TXE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

419612:GJB3
gene id: 419612:GJB3
uniprot id: A0A8B6YI49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

419612:ARAF
gene id: 419612:ARAF
uniprot id: A0A8B8SMR6
uniprot id: A0A8B8SP30
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

419612:GPR37
gene id: 419612:GPR37
uniprot id: A0A8B6YJL3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:AMBP
gene id: 419612:AMBP
uniprot id: A0A8B6YKK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Endoplasmic reticulum
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer. Also occurs as a complex with tryptase in mast cells.
messages: Nucleus membrane
messages: cytosol
messages: extracellular matrix

419612:MYO1D
gene id: 419612:MYO1D
uniprot id: A0A8B8R8Q4
uniprot id: A0A8B8R999
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

419612:NCBP3
gene id: 419612:NCBP3
uniprot id: A0A8B8UH29
uniprot id: A0A8B8UHP1
names: Similarity
messages: Belongs to the NCBP3 family.

419612:EVL
gene id: 419612:EVL
uniprot id: A0A8B8T8E1
uniprot id: A0A8B8T8E6
uniprot id: A0A8B8T8E8
uniprot id: A0A8B8T8J4
uniprot id: A0A8B8T8W8
uniprot id: A0A8B8T9E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration.
messages: cytoskeleton

419612:HSP90AB1
gene id: 419612:HSP90AB1
uniprot id: A0A8B6YKR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

419612:LOC102512076
gene id: 419612:LOC102512076
uniprot id: S9XPA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MDFIC
gene id: 419612:MDFIC
uniprot id: A0A8B8TBB8
uniprot id: A0A8B8TBC2
uniprot id: A0A8B8TBC3
uniprot id: A0A8B8TBG2
uniprot id: A0A8B8TBP4
uniprot id: A0A8B8TCI2
names: Similarity
messages: Belongs to the MDFI family.

419612:TM6SF2
gene id: 419612:TM6SF2
uniprot id: A0A8B6YH52
uniprot id: A0A8B7KB84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

419612:EXT2
gene id: 419612:EXT2
uniprot id: A0A8B6YF79
uniprot id: A0A8B8TQ43
uniprot id: A0A8B8TQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:SLC8B1
gene id: 419612:SLC8B1
uniprot id: A0A8B8SCW6
uniprot id: A0A8B8SE12
names: Subcellular Location Annotation
messages: Membrane

419612:CLDN10
gene id: 419612:CLDN10
uniprot id: A0A8B6YLH2
uniprot id: S9WIA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

419612:DACT2
gene id: 419612:DACT2
uniprot id: A0A8B8TGA2
names: Similarity
messages: Belongs to the dapper family.

419612:AGPAT5
gene id: 419612:AGPAT5
uniprot id: A0A8B8S399
uniprot id: A0A8B8S4U6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

419612:BLOC1S2
gene id: 419612:BLOC1S2
uniprot id: A0A8B6YE46
names: Similarity
messages: Belongs to the BLOC1S2 family.

419612:LOC102516649
gene id: 419612:LOC102516649
uniprot id: S9YN37
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102524156
gene id: 419612:LOC102524156
uniprot id: A0A8B7KFX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CLCN3
gene id: 419612:CLCN3
uniprot id: A0A8B8S9I6
uniprot id: A0A8B8S9J0
uniprot id: A0A8B8SAR3
uniprot id: A0A8B8SAX2
uniprot id: A0A8B8SBV4
uniprot id: A0A8B8SBV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

419612:PAF1
gene id: 419612:PAF1
uniprot id: A0A8B8TI92
uniprot id: S9XE63
names: Similarity
messages: Belongs to the PAF1 family.

419612:RIOK3
gene id: 419612:RIOK3
uniprot id: A0A8B6YMX4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.

419612:VPS36
gene id: 419612:VPS36
uniprot id: A0A8B8UCR2
uniprot id: A0A8B8UCU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

419612:MMP16
gene id: 419612:MMP16
uniprot id: A0A8B6YNN4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

419612:AURKC
gene id: 419612:AURKC
uniprot id: A0A8B6YFW7
uniprot id: A0A8B7KAM9
uniprot id: A0A8B8TMM0
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

419612:LOC102504562
gene id: 419612:LOC102504562
uniprot id: A0A8B8SCP2
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

419612:ERGIC1
gene id: 419612:ERGIC1
uniprot id: A0A8B8RSQ2
uniprot id: A0A8B8RSQ5
uniprot id: A0A8B8RTM0
uniprot id: A0A8B8RUC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

419612:FBXO9
gene id: 419612:FBXO9
uniprot id: A0A8B8RPQ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.
messages: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability. Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1. Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway. Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation.

419612:PGK1
gene id: 419612:PGK1
uniprot id: A0A8B6YMU8
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

419612:PEBP4
gene id: 419612:PEBP4
uniprot id: A0A8B7K685
uniprot id: A0A8B8S9S1
uniprot id: A0A8B8SAZ7
uniprot id: A0A8B8SB47
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

419612:ACTR8
gene id: 419612:ACTR8
uniprot id: A0A8B7KAW0
uniprot id: A0A8B8R883
uniprot id: A0A8B8RAX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

419612:MEGF6
gene id: 419612:MEGF6
uniprot id: A0A8B8U8H1
uniprot id: A0A8B8U8H2
uniprot id: A0A8B8U8H7
uniprot id: A0A8B8U9B7
uniprot id: A0A8B8U9C1
uniprot id: A0A8B8U9G4
uniprot id: A0A8B8U9N0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:GPR155
gene id: 419612:GPR155
uniprot id: A0A8B6YAM4
uniprot id: A0A8B8T0Y4
names: Subcellular Location Annotation
messages: Membrane

419612:BOP1
gene id: 419612:BOP1
uniprot id: A0A8B8RZS7
uniprot id: A0A8B8S1B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

419612:MMP27
gene id: 419612:MMP27
uniprot id: A0A8B6YGU0
uniprot id: A0A8B8TPE9
uniprot id: A0A8B8TQ31
uniprot id: A0A8B8TQK6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

419612:BMP8A
gene id: 419612:BMP8A
uniprot id: A0A8B8U5D8
uniprot id: A0A8B8U6I4
names: Similarity
messages: Belongs to the TGF-beta family.

419612:LOC102524056
gene id: 419612:LOC102524056
uniprot id: A0A8B8SAH3
names: Similarity
messages: Belongs to the PA28 family.

419612:TSHR
gene id: 419612:TSHR
uniprot id: A0A8B6YEX9
uniprot id: A0A8B8T7X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Interacts with heterodimer GPHA2:GPHB5; this interaction stimulates cAMP production. Interacts (via the PDZ-binding motif) with SCRIB; regulates TSHR trafficking and function.
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

419612:POGLUT2
gene id: 419612:POGLUT2
uniprot id: A0A8B6YPH5
uniprot id: A0A8B7KGR3
uniprot id: A0A8B8UDC8
names: Similarity
messages: Belongs to the KDELC family.

419612:LOC116662718
gene id: 419612:LOC116662718
uniprot id: A0A8B8SS16
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:NAA40
gene id: 419612:NAA40
uniprot id: A0A8B7K4Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

419612:STX1A
gene id: 419612:STX1A
uniprot id: A0A8B8RBT5
uniprot id: A0A8B8RBT8
uniprot id: A0A8B8REE6
names: Similarity
messages: Belongs to the syntaxin family.

419612:DEFB105B
gene id: 419612:DEFB105B
uniprot id: A0A8B8S3Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

419612:CPZ
gene id: 419612:CPZ
uniprot id: A0A8B8U3G9
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:BNIP3
gene id: 419612:BNIP3
uniprot id: A0A8B8TW56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

419612:GOT1L1
gene id: 419612:GOT1L1
uniprot id: A0A8B7KB42
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

419612:GSX1
gene id: 419612:GSX1
uniprot id: A0A8B8UDU2
names: Subcellular Location Annotation
messages: Nucleus

419612:EDEM1
gene id: 419612:EDEM1
uniprot id: A0A8B8RAB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

419612:CAMK2G
gene id: 419612:CAMK2G
uniprot id: A0A8B8S713
uniprot id: A0A8B8S716
uniprot id: A0A8B8S718
uniprot id: A0A8B8S721
uniprot id: A0A8B8S723
uniprot id: A0A8B8S726
uniprot id: A0A8B8S728
uniprot id: A0A8B8S731
uniprot id: A0A8B8S735
uniprot id: A0A8B8S739
uniprot id: A0A8B8S740
uniprot id: A0A8B8S744
uniprot id: A0A8B8S746
uniprot id: A0A8B8S749
uniprot id: A0A8B8S751
uniprot id: A0A8B8S8C4
uniprot id: A0A8B8S8D4
uniprot id: A0A8B8S8D8
uniprot id: A0A8B8S8E3
uniprot id: A0A8B8S8E8
uniprot id: A0A8B8S8F3
uniprot id: A0A8B8S8I5
uniprot id: A0A8B8S8J0
uniprot id: A0A8B8S8J4
uniprot id: A0A8B8S8J9
uniprot id: A0A8B8S8K3
uniprot id: A0A8B8S8K8
uniprot id: A0A8B8S8L4
uniprot id: A0A8B8S987
uniprot id: A0A8B8S991
uniprot id: A0A8B8S997
uniprot id: A0A8B8S9A3
uniprot id: A0A8B8S9A8
uniprot id: A0A8B8S9B3
uniprot id: A0A8B8S9C2
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

419612:CLDN23
gene id: 419612:CLDN23
uniprot id: A0A8B6YI48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

419612:ARRB2
gene id: 419612:ARRB2
uniprot id: A0A8B8UIY6
names: Similarity
messages: Belongs to the arrestin family.

419612:LMX1B
gene id: 419612:LMX1B
uniprot id: A0A8B8SWK8
uniprot id: A0A8B8SWZ0
names: Subcellular Location Annotation
messages: Nucleus

419612:STMN2
gene id: 419612:STMN2
uniprot id: A0A8B8S8P7
names: Similarity
messages: Belongs to the stathmin family.

419612:LOC106728934
gene id: 419612:LOC106728934
uniprot id: A0A8B7K635
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SGK1
gene id: 419612:SGK1
uniprot id: A0A8B6YIR4
uniprot id: A0A8B6YIT2
uniprot id: A0A8B6YJ07
uniprot id: A0A8B6YMM4
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

419612:WRN
gene id: 419612:WRN
uniprot id: A0A8B7KGF4
uniprot id: A0A8B7KHG3
uniprot id: A0A8B7KIA8
uniprot id: A0A8B8S2X8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

419612:SDR42E2
gene id: 419612:SDR42E2
uniprot id: A0A8B8RHM5
uniprot id: A0A8B8RI51
names: Similarity
messages: Belongs to the 3-beta-HSD family.

419612:AP1S3
gene id: 419612:AP1S3
uniprot id: A0A8B8T267
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Membrane
messages: clathrin-coated pit

419612:CNNM3
gene id: 419612:CNNM3
uniprot id: A0A8B6Y9E7
uniprot id: A0A8B7K581
uniprot id: A0A8B8S5J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

419612:HDDC2
gene id: 419612:HDDC2
uniprot id: A0A8B6YNK9
uniprot id: A0A8B7KD38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

419612:GDE1
gene id: 419612:GDE1
uniprot id: A0A8B6Y8U2
uniprot id: A0A8B8RHT3
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

419612:GLE1
gene id: 419612:GLE1
uniprot id: A0A8B6YCU2
uniprot id: A0A8B8SWT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

419612:YPEL2
gene id: 419612:YPEL2
uniprot id: A0A8B8UIR7
uniprot id: A0A8B8UIT5
names: Similarity
messages: Belongs to the yippee family.

419612:LOC102519905
gene id: 419612:LOC102519905
uniprot id: A0A8B6YNN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TGFBR1
gene id: 419612:TGFBR1
uniprot id: A0A8B8SVD1
uniprot id: A0A8B8SVW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

419612:SYNGR4
gene id: 419612:SYNGR4
uniprot id: A0A8B8TPV2
uniprot id: T0MF62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

419612:MRPL13
gene id: 419612:MRPL13
uniprot id: A0A8B6YIB0
uniprot id: A0A8B7KB31
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

419612:LOC102505466
gene id: 419612:LOC102505466
uniprot id: A0A8B8TVR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102518691
gene id: 419612:LOC102518691
uniprot id: S9XHF2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.

419612:LOC102518081
gene id: 419612:LOC102518081
uniprot id: A0A8B7K7A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
messages: Secreted

419612:PROKR2
gene id: 419612:PROKR2
uniprot id: A0A8B8RKD0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:HMGB2
gene id: 419612:HMGB2
uniprot id: A0A8B8SAD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

419612:GNB3
gene id: 419612:GNB3
uniprot id: S9X966
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

419612:LOC102504774
gene id: 419612:LOC102504774
uniprot id: A0A8B6YGI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FARS2
gene id: 419612:FARS2
uniprot id: A0A8B8RKH3
uniprot id: A0A8B8RLY3
uniprot id: A0A8B8RLY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

419612:EPHA10
gene id: 419612:EPHA10
uniprot id: A0A8B8UBB2
names: Subcellular Location Annotation
messages: Membrane

419612:POU2F1
gene id: 419612:POU2F1
uniprot id: A0A8B6YNG4
uniprot id: A0A8B8RPJ2
uniprot id: A0A8B8RR61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.

419612:NUDT1
gene id: 419612:NUDT1
uniprot id: A0A8B8RCT3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

419612:LIPT2
gene id: 419612:LIPT2
uniprot id: A0A8B7K8G3
uniprot id: A0A8B8TTH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Mitochondrion

419612:TVP23A
gene id: 419612:TVP23A
uniprot id: A0A8B8RFF8
uniprot id: A0A8B8RFM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

419612:LOC102517476
gene id: 419612:LOC102517476
uniprot id: A0A8B7KCE9
names: Similarity
messages: Belongs to the SPIN/STSY family.

419612:PDSS2
gene id: 419612:PDSS2
uniprot id: A0A8B6YJ67
uniprot id: A0A8B8TEB0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

419612:GOSR1
gene id: 419612:GOSR1
uniprot id: A0A8B6YFM7
uniprot id: A0A8B6YGV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

419612:LOC102519227
gene id: 419612:LOC102519227
uniprot id: A0A8B7KGC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:NUP88
gene id: 419612:NUP88
uniprot id: A0A8B6Y8A0
uniprot id: A0A8B8UIN7
names: Subcellular Location Annotation
messages: nuclear pore complex

419612:CCNH
gene id: 419612:CCNH
uniprot id: A0A8B8SMU1
uniprot id: A0A8B8SMU6
uniprot id: A0A8B8SMV2
uniprot id: A0A8B8SQ24
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

419612:LOC102517921
gene id: 419612:LOC102517921
uniprot id: A0A8B6YE51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:DRC1
gene id: 419612:DRC1
uniprot id: A0A8B7KD77
uniprot id: A0A8B8UFH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC1 family.
messages: cilium axoneme
messages: flagellum axoneme

419612:TMEM184B
gene id: 419612:TMEM184B
uniprot id: A0A8B8U0M2
uniprot id: A0A8B8U0M6
uniprot id: A0A8B8U1N3
uniprot id: S9XL23
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102514118
gene id: 419612:LOC102514118
uniprot id: A0A8B6Y993
uniprot id: A0A8B8R7J8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.

419612:SLC39A9
gene id: 419612:SLC39A9
uniprot id: A0A8B6YH08
uniprot id: A0A8B7KAZ9
uniprot id: A0A8B8T7B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

419612:ALDOA
gene id: 419612:ALDOA
uniprot id: A0A8B8RGI4
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

419612:TRIM9
gene id: 419612:TRIM9
uniprot id: A0A8B6YN52
uniprot id: A0A8B7KFE6
uniprot id: A0A8B8T6L8
uniprot id: A0A8B8T6N9
uniprot id: A0A8B8T6X4
uniprot id: A0A8B8T798
uniprot id: A0A8B8T7J1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: cytoskeleton

419612:GALC
gene id: 419612:GALC
uniprot id: A0A8B8T7Y1
uniprot id: A0A8B8T7Y4
uniprot id: A0A8B8T8G3
uniprot id: A0A8B8T8W7
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

419612:ST3GAL1
gene id: 419612:ST3GAL1
uniprot id: S9WNX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

419612:LOC106730769
gene id: 419612:LOC106730769
uniprot id: A0A8B8SK49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

419612:MRPL40
gene id: 419612:MRPL40
uniprot id: A0A8B8SCL3
uniprot id: A0A8B8SF44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

419612:BACE1
gene id: 419612:BACE1
uniprot id: A0A8B6Y8M2
uniprot id: A0A8B8SFL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

419612:RNASE11
gene id: 419612:RNASE11
uniprot id: A0A8B6YLA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

419612:FA2H
gene id: 419612:FA2H
uniprot id: A0A8B8TK62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:ACER1
gene id: 419612:ACER1
uniprot id: A0A8B6Y913
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

419612:SUCLA2
gene id: 419612:SUCLA2
uniprot id: A0A8B8UCI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

419612:BROX
gene id: 419612:BROX
uniprot id: A0A8B6YIH6
names: Similarity
messages: Belongs to the BROX family.

419612:TAAR5
gene id: 419612:TAAR5
uniprot id: A0A8B8TF28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

419612:LOC116663373
gene id: 419612:LOC116663373
uniprot id: A0A8B8SZF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:TADA2A
gene id: 419612:TADA2A
uniprot id: A0A8B8UI35
names: Subcellular Location Annotation
messages: Nucleus

419612:NIPAL2
gene id: 419612:NIPAL2
uniprot id: A0A8B8S102
uniprot id: A0A8B8S2B7
uniprot id: A0A8B8S2K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

419612:CARTPT
gene id: 419612:CARTPT
uniprot id: A0A8B6YFV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

419612:SSTR2
gene id: 419612:SSTR2
uniprot id: A0A8B6Y7W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

419612:CPNE4
gene id: 419612:CPNE4
uniprot id: A0A8B8TU36
names: Similarity
messages: Belongs to the copine family.

419612:TSPO2
gene id: 419612:TSPO2
uniprot id: A0A8B6YPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

419612:LOC102515739
gene id: 419612:LOC102515739
uniprot id: A0A8B7K5K4
names: Function
names: Subcellular Location Annotation
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
messages: Mitochondrion inner membrane

419612:CCDC34
gene id: 419612:CCDC34
uniprot id: A0A8B6YPF0
uniprot id: A0A8B7KGE1
names: Subcellular Location Annotation
messages: flagellum

419612:MYBL1
gene id: 419612:MYBL1
uniprot id: A0A8B6YNG2
uniprot id: A0A8B6YQ05
uniprot id: A0A8B8S818
names: Subcellular Location Annotation
messages: Nucleus

419612:POLR3C
gene id: 419612:POLR3C
uniprot id: A0A8B6Y8U0
uniprot id: A0A8B7K3U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

419612:LOC102515708
gene id: 419612:LOC102515708
uniprot id: A0A8B7KDF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102505008
gene id: 419612:LOC102505008
uniprot id: A0A8B8SHW3
names: Similarity
messages: Belongs to the SUA5 family.

419612:ALDH5A1
gene id: 419612:ALDH5A1
uniprot id: A0A8B7K888
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

419612:SETD3
gene id: 419612:SETD3
uniprot id: A0A8B8T8C7
uniprot id: A0A8B8T8V6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm
messages: Interacts with MYOD1.

419612:POLR2A
gene id: 419612:POLR2A
uniprot id: A0A8B8UKA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

419612:ADGRA2
gene id: 419612:ADGRA2
uniprot id: A0A8B8S422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

419612:PHACTR1
gene id: 419612:PHACTR1
uniprot id: A0A8B8RM45
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

419612:SRPRB
gene id: 419612:SRPRB
uniprot id: A0A8B6YAT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:IRF5
gene id: 419612:IRF5
uniprot id: A0A8B8TAC4
uniprot id: A0A8B8TAS3
names: Subcellular Location Annotation
messages: Nucleus

419612:SH3GL3
gene id: 419612:SH3GL3
uniprot id: A0A8B8S480
uniprot id: A0A8B8S486
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

419612:INTU
gene id: 419612:INTU
uniprot id: A0A8B6YA06
uniprot id: A0A8B8RMD1
uniprot id: A0A8B8RP28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

419612:LOC102522976
gene id: 419612:LOC102522976
uniprot id: A0A8B6YFC0
uniprot id: A0A8B8TAF6
uniprot id: A0A8B8TAU4
names: Similarity
messages: Belongs to the peptidase M14 family.

419612:SLC9A2
gene id: 419612:SLC9A2
uniprot id: A0A8B8SJR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Interacts with CHP1 and CHP2.
messages: Membrane

419612:SLC13A1
gene id: 419612:SLC13A1
uniprot id: A0A8B7K9C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

419612:FAM83E
gene id: 419612:FAM83E
uniprot id: A0A8B6YSF3
uniprot id: A0A8B8TH12
names: Similarity
messages: Belongs to the FAM83 family.

419612:LOC102504468
gene id: 419612:LOC102504468
uniprot id: A0A8B6Y9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PRF1
gene id: 419612:PRF1
uniprot id: A0A8B6YCK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

419612:CALR3
gene id: 419612:CALR3
uniprot id: S9YM21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

419612:TERF2
gene id: 419612:TERF2
uniprot id: A0A8B7K783
uniprot id: A0A8B8TJW5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus
messages: telomere

419612:LOC102512307
gene id: 419612:LOC102512307
uniprot id: A0A8B6Y767
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SNCA
gene id: 419612:SNCA
uniprot id: A0A8B6YGB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse
messages: axon

419612:TRAPPC13
gene id: 419612:TRAPPC13
uniprot id: A0A8B6YGM5
uniprot id: A0A8B6YGM7
uniprot id: A0A8B6YHW0
uniprot id: A0A8B6YKM3
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

419612:SLC35E3
gene id: 419612:SLC35E3
uniprot id: A0A8B6YNP1
uniprot id: A0A8B8U510
names: Subcellular Location Annotation
messages: Membrane

419612:HACL1
gene id: 419612:HACL1
uniprot id: A0A8B6YKU6
uniprot id: A0A8B8TS26
names: Similarity
messages: Belongs to the TPP enzyme family.

419612:SLC37A2
gene id: 419612:SLC37A2
uniprot id: A0A8B8SFM3
uniprot id: A0A8B8SFQ5
uniprot id: A0A8B8SH02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

419612:PTAFR
gene id: 419612:PTAFR
uniprot id: S9XM56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

419612:SUMO1
gene id: 419612:SUMO1
uniprot id: A0A8B6YK95
uniprot id: A0A8B8T1I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

419612:SGIP1
gene id: 419612:SGIP1
uniprot id: A0A8B7KE40
uniprot id: A0A8B7KE46
uniprot id: A0A8B7KGA5
uniprot id: A0A8B8U746
uniprot id: A0A8B8U747
uniprot id: A0A8B8U753
uniprot id: A0A8B8U754
uniprot id: A0A8B8U7Z5
uniprot id: A0A8B8U852
uniprot id: A0A8B8U858
uniprot id: A0A8B8U861
uniprot id: A0A8B8U866
names: Function
names: Subcellular Location Annotation
messages: May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.
messages: clathrin-coated pit

419612:NUCB2
gene id: 419612:NUCB2
uniprot id: A0A8B7KHP6
uniprot id: A0A8B8TRC1
names: Similarity
messages: Belongs to the nucleobindin family.

419612:CMBL
gene id: 419612:CMBL
uniprot id: A0A8B7KGL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

419612:ATP6V0C
gene id: 419612:ATP6V0C
uniprot id: A0A8B8RDS2
uniprot id: A0A8B8RDY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

419612:BCL2A1
gene id: 419612:BCL2A1
uniprot id: A0A8B8S5I6
names: Similarity
messages: Belongs to the Bcl-2 family.

419612:OPA1
gene id: 419612:OPA1
uniprot id: A0A8B6YAL5
uniprot id: A0A8B6YE40
uniprot id: A0A8B7K625
uniprot id: A0A8B7K657
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

419612:JPH4
gene id: 419612:JPH4
uniprot id: A0A8B8T5S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

419612:ZKSCAN1
gene id: 419612:ZKSCAN1
uniprot id: A0A8B6YDJ9
uniprot id: A0A8B7K856
names: Subcellular Location Annotation
messages: Nucleus

419612:TENM2
gene id: 419612:TENM2
uniprot id: A0A8B8RST9
uniprot id: A0A8B8RUG2
uniprot id: A0A8B8RUH1
uniprot id: A0A8B8RUS0
uniprot id: A0A8B8RUS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:CLDN7
gene id: 419612:CLDN7
uniprot id: A0A8B8UJE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

419612:LOC116661675
gene id: 419612:LOC116661675
uniprot id: A0A8B8SL57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LHCGR
gene id: 419612:LHCGR
uniprot id: A0A8B8UFK3
uniprot id: A0A8B8UFM8
uniprot id: A0A8B8UGA5
uniprot id: A0A8B8UGB2
uniprot id: A0A8B8UGB6
uniprot id: A0A8B8UGC2
uniprot id: A0A8B8UH03
uniprot id: A0A8B8UH07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

419612:GSDMA
gene id: 419612:GSDMA
uniprot id: A0A8B6Y7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

419612:IDH3G
gene id: 419612:IDH3G
uniprot id: A0A8B8SNL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

419612:ARID3C
gene id: 419612:ARID3C
uniprot id: A0A8B8STJ0
uniprot id: A0A8B8SV46
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

419612:TLX3
gene id: 419612:TLX3
uniprot id: A0A8B8RXQ5
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102512338
gene id: 419612:LOC102512338
uniprot id: A0A8B8SM21
names: Similarity
messages: Belongs to the SPT20 family.

419612:NNMT
gene id: 419612:NNMT
uniprot id: A0A8B8SFH5
uniprot id: A0A8B8SGR3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

419612:SPECC1L
gene id: 419612:SPECC1L
uniprot id: A0A8B8SCB9
uniprot id: A0A8B8SDH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

419612:SETD7
gene id: 419612:SETD7
uniprot id: A0A8B8RNZ8
uniprot id: A0A8B8RPE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
messages: Nucleus

419612:ERBB2
gene id: 419612:ERBB2
uniprot id: A0A8B8R996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

419612:CENPV
gene id: 419612:CENPV
uniprot id: A0A8B8UK90
names: Similarity
messages: Belongs to the Gfa family.

419612:CLCA2
gene id: 419612:CLCA2
uniprot id: A0A8B6YKA7
names: Similarity
messages: Belongs to the CLCR family.

419612:FAM207A
gene id: 419612:FAM207A
uniprot id: A0A8B8TYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

419612:LOC102517906
gene id: 419612:LOC102517906
uniprot id: A0A8B8R5D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

419612:PBX3
gene id: 419612:PBX3
uniprot id: A0A8B8SW93
uniprot id: A0A8B8SWH0
uniprot id: A0A8B8SXJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

419612:LOC102522315
gene id: 419612:LOC102522315
uniprot id: A0A8B6YG49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

419612:OXER1
gene id: 419612:OXER1
uniprot id: A0A8B8UG40
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:ATP1B4
gene id: 419612:ATP1B4
uniprot id: A0A8B6YQA9
uniprot id: A0A8B6YS68
uniprot id: A0A8B8SL19
uniprot id: A0A8B8SL27
uniprot id: A0A8B8SM62
uniprot id: A0A8B8SNC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

419612:ALLC
gene id: 419612:ALLC
uniprot id: A0A8B8UDZ3
names: Function
names: Similarity
messages: Belongs to the allantoicase family.
messages: The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals.

419612:MRPS2
gene id: 419612:MRPS2
uniprot id: A0A8B8SXL6
uniprot id: A0A8B8SY17
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

419612:LOC116661419
gene id: 419612:LOC116661419
uniprot id: A0A8B8SGQ6
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

419612:GBP6
gene id: 419612:GBP6
uniprot id: A0A8B7KFC7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

419612:ADCY7
gene id: 419612:ADCY7
uniprot id: A0A8B8TIU4
uniprot id: A0A8B8TIV3
uniprot id: A0A8B8TIW7
uniprot id: A0A8B8TJ08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

419612:UGGT2
gene id: 419612:UGGT2
uniprot id: A0A8B8UDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

419612:TAS1R2
gene id: 419612:TAS1R2
uniprot id: A0A8B6YIN1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:LOC106730937
gene id: 419612:LOC106730937
uniprot id: A0A8B7KH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

419612:CWF19L1
gene id: 419612:CWF19L1
uniprot id: A0A8B6YDR9
uniprot id: A0A8B8TXG1
uniprot id: A0A8B8TXG3
uniprot id: A0A8B8TYI8
names: Similarity
messages: Belongs to the CWF19 family.

419612:LOC102518897
gene id: 419612:LOC102518897
uniprot id: A0A8B7KFT7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:NAGLU
gene id: 419612:NAGLU
uniprot id: A0A8B8R555
names: Subcellular Location Annotation
messages: Lysosome

419612:GJA4
gene id: 419612:GJA4
uniprot id: S9WMW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

419612:CXCR5
gene id: 419612:CXCR5
uniprot id: A0A8B7K5Y9
uniprot id: S9XCI6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:TLE5
gene id: 419612:TLE5
uniprot id: A0A8B8RX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

419612:PIF1
gene id: 419612:PIF1
uniprot id: A0A8B8T3J8
uniprot id: A0A8B8T3K3
uniprot id: A0A8B8T3W7
uniprot id: A0A8B8T4B4
uniprot id: A0A8B8T4D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family.
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

419612:PRSS12
gene id: 419612:PRSS12
uniprot id: A0A8B6YGF5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: Secreted

419612:LOC102518639
gene id: 419612:LOC102518639
uniprot id: A0A8B8S998
names: Similarity
messages: Belongs to the serpin family.

419612:LOC102512165
gene id: 419612:LOC102512165
uniprot id: A0A8B8SU64
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

419612:NRM
gene id: 419612:NRM
uniprot id: A0A8B6YLK9
uniprot id: A0A8B6YLT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Membrane
messages: Nucleus inner membrane

419612:SMC1B
gene id: 419612:SMC1B
uniprot id: A0A8B6Y824
uniprot id: A0A8B8U158
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

419612:CAPZB
gene id: 419612:CAPZB
uniprot id: A0A8B6YIL8
uniprot id: A0A8B7KCB0
uniprot id: A0A8B8U9E3
uniprot id: A0A8B8UAM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

419612:LIM2
gene id: 419612:LIM2
uniprot id: A0A8B8TP70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis.

419612:CIAO1
gene id: 419612:CIAO1
uniprot id: A0A8B6YCU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Interacts with WT1. Interacts with FAM96A.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

419612:RDH5
gene id: 419612:RDH5
uniprot id: A0A8B6YEY7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:LOC102523730
gene id: 419612:LOC102523730
uniprot id: A0A8B8TK92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

419612:ATE1
gene id: 419612:ATE1
uniprot id: A0A8B8TWF2
uniprot id: A0A8B8TWF3
uniprot id: A0A8B8TWF7
uniprot id: A0A8B8TWG4
uniprot id: A0A8B8TWG9
uniprot id: A0A8B8TXH0
uniprot id: A0A8B8TXT7
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

419612:LOC102514055
gene id: 419612:LOC102514055
uniprot id: A0A8B6YP21
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CANT1
gene id: 419612:CANT1
uniprot id: A0A8B8R3K3
names: Similarity
messages: Belongs to the apyrase family.

419612:FHIT
gene id: 419612:FHIT
uniprot id: A0A8B8R7U1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SSR4
gene id: 419612:SSR4
uniprot id: A0A8B8SNL5
uniprot id: A0A8B8SPJ4
uniprot id: A0A8B8SPV3
uniprot id: A0A8B8SQR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

419612:TMCC1
gene id: 419612:TMCC1
uniprot id: A0A8B7K937
names: Similarity
messages: Belongs to the TEX28 family.

419612:PRKCB
gene id: 419612:PRKCB
uniprot id: A0A8B8RFJ7
uniprot id: A0A8B8RFR5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

419612:CCDC130
gene id: 419612:CCDC130
uniprot id: S9XK18
names: Similarity
messages: Belongs to the CWC16 family.

419612:CHRNA9
gene id: 419612:CHRNA9
uniprot id: A0A8B6YKL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:LOC102511863
gene id: 419612:LOC102511863
uniprot id: A0A8B6YRX1
uniprot id: A0A8B7KFS8
uniprot id: A0A8B8S6Z8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

419612:TUT1
gene id: 419612:TUT1
uniprot id: A0A8B6YE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Nucleus speckle
messages: nucleolus

419612:CLDN16
gene id: 419612:CLDN16
uniprot id: A0A8B6YKI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

419612:PTGER3
gene id: 419612:PTGER3
uniprot id: A0A8B6YL13
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:TMC5
gene id: 419612:TMC5
uniprot id: A0A8B7K4T6
uniprot id: A0A8B8RFV4
uniprot id: A0A8B8RIB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

419612:MDM4
gene id: 419612:MDM4
uniprot id: A0A8B8RY54
uniprot id: A0A8B8RZJ1
uniprot id: A0A8B8RZS8
uniprot id: A0A8B8RZT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

419612:P2RY2
gene id: 419612:P2RY2
uniprot id: A0A8B8TSH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:SFRP2
gene id: 419612:SFRP2
uniprot id: A0A8B6YMC0
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MYO1B
gene id: 419612:MYO1B
uniprot id: A0A8B6YHE2
uniprot id: A0A8B8T1P2
uniprot id: A0A8B8T1U5
uniprot id: A0A8B8T270
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

419612:TMED4
gene id: 419612:TMED4
uniprot id: A0A8B8TDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:BLOC1S6
gene id: 419612:BLOC1S6
uniprot id: A0A8B6Y7B5
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

419612:DEFB134
gene id: 419612:DEFB134
uniprot id: A0A8B8S8Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

419612:MERTK
gene id: 419612:MERTK
uniprot id: A0A8B8S643
uniprot id: A0A8B8S7F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

419612:TAS2R4
gene id: 419612:TAS2R4
uniprot id: A0A8B8TAY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

419612:USP30
gene id: 419612:USP30
uniprot id: A0A8B8SBB6
uniprot id: A0A8B8SDU3
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

419612:DAXX
gene id: 419612:DAXX
uniprot id: A0A8B8RLI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

419612:STOML3
gene id: 419612:STOML3
uniprot id: A0A8B6YES3
uniprot id: A0A8B8UDF7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

419612:PEX2
gene id: 419612:PEX2
uniprot id: S9WXG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

419612:NACC2
gene id: 419612:NACC2
uniprot id: A0A8B8SXK6
uniprot id: A0A8B8SXU3
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC116664174
gene id: 419612:LOC116664174
uniprot id: A0A8B8T666
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

419612:LOC102512017
gene id: 419612:LOC102512017
uniprot id: A0A8B6Y9Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

419612:ACTN4
gene id: 419612:ACTN4
uniprot id: A0A8B6Y4E7
uniprot id: A0A8B6Y5F1
uniprot id: A0A8B6Y689
uniprot id: A0A8B6Y8K2
uniprot id: A0A8B8TIB7
uniprot id: A0A8B8TIF1
names: Similarity
messages: Belongs to the alpha-actinin family.

419612:FZR1
gene id: 419612:FZR1
uniprot id: A0A8B8RV76
uniprot id: A0A8B8RWR4
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

419612:CDC14B
gene id: 419612:CDC14B
uniprot id: A0A8B8STC1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

419612:LOC102516001
gene id: 419612:LOC102516001
uniprot id: A0A8B8SNV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

419612:SYCE1L
gene id: 419612:SYCE1L
uniprot id: A0A8B8TKB2
uniprot id: A0A8B8TKB6
uniprot id: A0A8B8TKC5
uniprot id: A0A8B8TKD0
uniprot id: A0A8B8TKN0
uniprot id: A0A8B8TLJ7
uniprot id: A0A8B8TLK2
names: Similarity
messages: Belongs to the SYCE family.

419612:CEBPA
gene id: 419612:CEBPA
uniprot id: A0A8B6Y791
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

419612:ACVRL1
gene id: 419612:ACVRL1
uniprot id: A0A8B8U2G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

419612:LOC106729218
gene id: 419612:LOC106729218
uniprot id: A0A8B7K864
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CD82
gene id: 419612:CD82
uniprot id: A0A8B8TQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:DNAJA2
gene id: 419612:DNAJA2
uniprot id: A0A8B8TIS3
names: Subcellular Location Annotation
messages: Membrane

419612:INSIG2
gene id: 419612:INSIG2
uniprot id: A0A8B6YMZ9
uniprot id: A0A8B8SZB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

419612:PDK4
gene id: 419612:PDK4
uniprot id: A0A8B6YDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

419612:POLH
gene id: 419612:POLH
uniprot id: A0A8B6YKT3
uniprot id: A0A8B7KE25
uniprot id: A0A8B8RMH7
names: Subcellular Location Annotation
messages: Nucleus

419612:FAM120C
gene id: 419612:FAM120C
uniprot id: A0A8B8SNC8
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

419612:CELF1
gene id: 419612:CELF1
uniprot id: A0A8B8TQJ1
uniprot id: A0A8B8TQJ5
uniprot id: A0A8B8TQJ8
uniprot id: A0A8B8TQJ9
uniprot id: A0A8B8TQK3
uniprot id: A0A8B8TQK4
uniprot id: A0A8B8TRA8
uniprot id: A0A8B8TRP7
uniprot id: A0A8B8TRQ2
uniprot id: A0A8B8TRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

419612:PKP2
gene id: 419612:PKP2
uniprot id: A0A8B8SGM7
names: Similarity
messages: Belongs to the beta-catenin family.

419612:ELK1
gene id: 419612:ELK1
uniprot id: A0A8B8SNS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:IMMP2L
gene id: 419612:IMMP2L
uniprot id: A0A8B8TBE5
uniprot id: A0A8B8TBE6
uniprot id: A0A8B8TBF0
uniprot id: A0A8B8TBI9
uniprot id: A0A8B8TBS1
uniprot id: A0A8B8TBS6
uniprot id: A0A8B8TCK9
uniprot id: A0A8B8TCL4
uniprot id: A0A8B8TCL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

419612:FOXI3
gene id: 419612:FOXI3
uniprot id: A0A8B8S6Z2
names: Subcellular Location Annotation
messages: Nucleus

419612:MAN2C1
gene id: 419612:MAN2C1
uniprot id: A0A8B8S3Z3
uniprot id: A0A8B8S3Z7
uniprot id: A0A8B8S5A2
uniprot id: A0A8B8S5X1
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

419612:CASP6
gene id: 419612:CASP6
uniprot id: A0A8B8RKE1
names: Similarity
messages: Belongs to the peptidase C14A family.

419612:SERPINH1
gene id: 419612:SERPINH1
uniprot id: S9YQ15
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

419612:LOC102518610
gene id: 419612:LOC102518610
uniprot id: A0A8B8UD64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

419612:LOC102523568
gene id: 419612:LOC102523568
uniprot id: S9XDA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SMS
gene id: 419612:SMS
uniprot id: A0A8B8SQ17
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

419612:EPN3
gene id: 419612:EPN3
uniprot id: A0A8B8UHG8
uniprot id: A0A8B8UIR0
names: Similarity
messages: Belongs to the epsin family.

419612:LOC102511140
gene id: 419612:LOC102511140
uniprot id: S9XKY7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:CHAC1
gene id: 419612:CHAC1
uniprot id: A0A8B8T529
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

419612:ACTL6A
gene id: 419612:ACTL6A
uniprot id: A0A8B8TC06
names: Similarity
messages: Belongs to the actin family.

419612:LOC102520021
gene id: 419612:LOC102520021
uniprot id: A0A8B6YPV1
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

419612:ECHDC2
gene id: 419612:ECHDC2
uniprot id: A0A8B8U6G1
uniprot id: A0A8B8U6G7
uniprot id: A0A8B8U7C5
uniprot id: A0A8B8U7D3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

419612:AK3
gene id: 419612:AK3
uniprot id: A0A8B8SUJ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

419612:NPM2
gene id: 419612:NPM2
uniprot id: A0A8B7K7B2
uniprot id: A0A8B8S9L3
uniprot id: A0A8B8SBY6
names: Similarity
messages: Belongs to the nucleoplasmin family.

419612:WNT7B
gene id: 419612:WNT7B
uniprot id: A0A8B8U181
uniprot id: A0A8B8U182
uniprot id: A0A8B8U1M0
uniprot id: A0A8B8U287
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

419612:LEPROT
gene id: 419612:LEPROT
uniprot id: A0A8B8U723
uniprot id: A0A8B8U843
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

419612:PALMD
gene id: 419612:PALMD
uniprot id: A0A8B6YPQ9
names: Similarity
messages: Belongs to the paralemmin family.

419612:FAM234B
gene id: 419612:FAM234B
uniprot id: A0A8B6YM24
names: Similarity
messages: Belongs to the FAM234 family.

419612:CORO2B
gene id: 419612:CORO2B
uniprot id: A0A8B7K4R2
uniprot id: A0A8B7K6U0
uniprot id: A0A8B8S491
uniprot id: A0A8B8S668
names: Similarity
messages: Belongs to the WD repeat coronin family.

419612:SIAH3
gene id: 419612:SIAH3
uniprot id: A0A8B7KBM8
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

419612:LOC102514829
gene id: 419612:LOC102514829
uniprot id: A0A8B8T6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

419612:CARMIL2
gene id: 419612:CARMIL2
uniprot id: A0A8B8TJN6
uniprot id: A0A8B8TJP8
uniprot id: A0A8B8TKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

419612:UBXN1
gene id: 419612:UBXN1
uniprot id: A0A8B6YCQ1
uniprot id: A0A8B7K811
names: Subcellular Location Annotation
messages: Cytoplasm

419612:RNPS1
gene id: 419612:RNPS1
uniprot id: A0A8B6Y6P1
uniprot id: A0A8B7KF06
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the splicing factor SR family.
messages: Found in mRNA splicing-dependent exon junction complexes (EJC). Found in a post-splicing complex with NXF1, RBM8A, UPF1, UPF2, UPF3A, UPF3B and RNPS1. Component of the heterotrimeric ASAP (apoptosis- and splicing-associated protein) and PSAP complexes consisting of RNPS1, SAP18 and either ACIN1 or PNN, respectively; the ASAP and PSAP complexes probably are formed mutually exclusive. Component of the active spliceosome. Associates with polysomes. Interacts with the cleaved p110 isoform of CDC2L1, CSNK2A1, PNN, SART3, SRP54, SRRM1 and TRA2B/SFRS10.
messages: Nucleus speckle

419612:TENT5D
gene id: 419612:TENT5D
uniprot id: A0A8B6YPW6
names: Similarity
messages: Belongs to the TENT family.

419612:ELF2
gene id: 419612:ELF2
uniprot id: A0A8B6YM92
uniprot id: A0A8B6YME5
uniprot id: A0A8B6YMH7
uniprot id: A0A8B6YNX0
uniprot id: A0A8B7KF73
uniprot id: A0A8B7KGA2
uniprot id: A0A8B7KH42
uniprot id: A0A8B8RNM4
uniprot id: A0A8B8RNN5
uniprot id: A0A8B8RP36
uniprot id: A0A8B8RP43
uniprot id: A0A8B8RQB8
uniprot id: A0A8B8RQE6
uniprot id: A0A8B8RQJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:ISY1
gene id: 419612:ISY1
uniprot id: A0A8B8RBP7
uniprot id: A0A8B8RCB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

419612:DBP
gene id: 419612:DBP
uniprot id: A0A8B8TH02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

419612:MTFP1
gene id: 419612:MTFP1
uniprot id: A0A8B6YFE0
names: Similarity
messages: Belongs to the MTFP1 family.

419612:TLR7
gene id: 419612:TLR7
uniprot id: A0A8B6YPG2
uniprot id: A0A8B8SML1
uniprot id: A0A8B8SPR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Endosome
messages: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production.
messages: Lysosome
messages: Membrane
messages: phagosome

419612:PLCB2
gene id: 419612:PLCB2
uniprot id: A0A8B8T546
uniprot id: A0A8B8T579
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

419612:TXK
gene id: 419612:TXK
uniprot id: A0A8B6YKI0
uniprot id: A0A8B8UF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

419612:SPIB
gene id: 419612:SPIB
uniprot id: A0A8B8TNG2
uniprot id: A0A8B8TNG3
uniprot id: A0A8B8TNG4
uniprot id: A0A8B8TP01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:COQ8A
gene id: 419612:COQ8A
uniprot id: A0A8B8RYA2
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

419612:CASC3
gene id: 419612:CASC3
uniprot id: A0A8B8RA20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Nucleus speckle
messages: dendrite
messages: perinuclear region

419612:COL4A3
gene id: 419612:COL4A3
uniprot id: A0A8B8T1Y2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

419612:RNASEK
gene id: 419612:RNASEK
uniprot id: A0A8B6Y8V6
uniprot id: A0A8B7K446
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

419612:ATP6AP1L
gene id: 419612:ATP6AP1L
uniprot id: A0A8B8SMC1
uniprot id: A0A8B8SPG9
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

419612:LOC102514641
gene id: 419612:LOC102514641
uniprot id: A0A8B8TXQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

419612:SLC27A5
gene id: 419612:SLC27A5
uniprot id: S9XPU8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

419612:LOC102517908
gene id: 419612:LOC102517908
uniprot id: A0A8B6YM00
uniprot id: A0A8B6YNH5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

419612:SV2C
gene id: 419612:SV2C
uniprot id: A0A8B8SJI3
uniprot id: A0A8B8SLW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

419612:TMEM184A
gene id: 419612:TMEM184A
uniprot id: A0A8B8RCQ5
uniprot id: A0A8B8RCR3
uniprot id: A0A8B8RCT4
uniprot id: A0A8B8RER4
uniprot id: A0A8B8RF98
names: Subcellular Location Annotation
messages: Membrane

419612:ATP8B2
gene id: 419612:ATP8B2
uniprot id: A0A8B6YCI4
uniprot id: A0A8B8RQ37
uniprot id: A0A8B8RQN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

419612:CD320
gene id: 419612:CD320
uniprot id: A0A8B8RW80
uniprot id: A0A8B8RXG1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MFSD9
gene id: 419612:MFSD9
uniprot id: A0A8B8SIK5
uniprot id: A0A8B8SIK8
uniprot id: A0A8B8SL11
names: Subcellular Location Annotation
messages: Membrane

419612:CA5A
gene id: 419612:CA5A
uniprot id: A0A8B6YFU1
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

419612:ZFP36
gene id: 419612:ZFP36
uniprot id: A0A8B6Y9P9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

419612:FLAD1
gene id: 419612:FLAD1
uniprot id: A0A8B7K568
uniprot id: A0A8B8RQ18
names: Function
names: Similarity
messages: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
messages: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

419612:GLDC
gene id: 419612:GLDC
uniprot id: A0A8B8SU03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

419612:CNGA4
gene id: 419612:CNGA4
uniprot id: A0A8B6YK88
names: Subcellular Location Annotation
messages: Membrane

419612:EBF3
gene id: 419612:EBF3
uniprot id: A0A8B8TW51
uniprot id: A0A8B8TW57
uniprot id: A0A8B8TW58
uniprot id: A0A8B8TW62
uniprot id: A0A8B8TW63
uniprot id: A0A8B8TW66
uniprot id: A0A8B8TW67
uniprot id: A0A8B8TW68
uniprot id: A0A8B8TW71
uniprot id: A0A8B8TW76
uniprot id: A0A8B8TX81
uniprot id: A0A8B8TX84
uniprot id: A0A8B8TX89
uniprot id: A0A8B8TXI9
uniprot id: A0A8B8TXJ4
uniprot id: A0A8B8TXJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

419612:SHQ1
gene id: 419612:SHQ1
uniprot id: A0A8B6Y7P1
uniprot id: A0A8B8R7L2
uniprot id: A0A8B8RAG2
names: Similarity
messages: Belongs to the SHQ1 family.

419612:DKK1
gene id: 419612:DKK1
uniprot id: A0A8B6YCN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

419612:ARSJ
gene id: 419612:ARSJ
uniprot id: A0A8B6YG41
uniprot id: A0A8B8RLP6
names: Similarity
messages: Belongs to the sulfatase family.

419612:LOC102515551
gene id: 419612:LOC102515551
uniprot id: A0A8B6Y6C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LBP
gene id: 419612:LBP
uniprot id: A0A8B8RJQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.
messages: Secreted
messages: When bound to LPS, interacts (via C-terminus) with soluble and membrane-bound CD14.

419612:LOC102509272
gene id: 419612:LOC102509272
uniprot id: A0A8B6YMF5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:NETO1
gene id: 419612:NETO1
uniprot id: A0A8B8S810
uniprot id: A0A8B8S816
uniprot id: A0A8B8S9A7
uniprot id: A0A8B8SA91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102510265
gene id: 419612:LOC102510265
uniprot id: S9WCY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:BCL2L10
gene id: 419612:BCL2L10
uniprot id: A0A8B8T477
uniprot id: A0A8B8T480
uniprot id: A0A8B8T4J3
names: Similarity
messages: Belongs to the Bcl-2 family.

419612:LOC102510001
gene id: 419612:LOC102510001
uniprot id: A0A8B7KBH2
names: Similarity
messages: Belongs to the SH3BGR family.

419612:SEC31A
gene id: 419612:SEC31A
uniprot id: A0A8B6YKD9
uniprot id: A0A8B6YKH1
uniprot id: A0A8B6YLU3
uniprot id: A0A8B7KDM2
uniprot id: A0A8B8R338
uniprot id: A0A8B8R350
uniprot id: A0A8B8R378
uniprot id: A0A8B8R3G0
uniprot id: A0A8B8R5D7
uniprot id: A0A8B8R5G3
uniprot id: A0A8B8R5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

419612:ODF2L
gene id: 419612:ODF2L
uniprot id: A0A8B8U7Q0
uniprot id: A0A8B8U7Q5
uniprot id: A0A8B8U8J2
uniprot id: A0A8B8U8J7
uniprot id: A0A8B8U8Q1
uniprot id: A0A8B8U8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

419612:PCMTD2
gene id: 419612:PCMTD2
uniprot id: A0A8B8RJU5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

419612:SLC12A4
gene id: 419612:SLC12A4
uniprot id: A0A8B8TJQ9
uniprot id: A0A8B8TK08
uniprot id: A0A8B8TKZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

419612:VOPP1
gene id: 419612:VOPP1
uniprot id: A0A8B8SB79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Endosome membrane
messages: Interacts with WWOX (via WW domain).
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

419612:CCT6B
gene id: 419612:CCT6B
uniprot id: A0A8B6YCB8
uniprot id: A0A8B8R6L3
uniprot id: A0A8B8R6L7
uniprot id: A0A8B8R6T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

419612:CLDN12
gene id: 419612:CLDN12
uniprot id: A0A8B7KH12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Membrane
messages: tight junction

419612:FGG
gene id: 419612:FGG
uniprot id: A0A8B6YKV1
uniprot id: S9WDV3
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

419612:DOLK
gene id: 419612:DOLK
uniprot id: S9X4I1
names: Similarity
messages: Belongs to the polyprenol kinase family.

419612:ZPBP2
gene id: 419612:ZPBP2
uniprot id: A0A8B6Y8E7
uniprot id: A0A8B6YBS4
uniprot id: A0A8B7K481
uniprot id: A0A8B8R753
uniprot id: A0A8B8R7B4
uniprot id: A0A8B8R9A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted
messages: acrosome

419612:LIPM
gene id: 419612:LIPM
uniprot id: A0A8B8TY81
uniprot id: A0A8B8TY84
uniprot id: A0A8B8TZJ5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

419612:ATXN1L
gene id: 419612:ATXN1L
uniprot id: A0A8B8TJZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

419612:COQ7
gene id: 419612:COQ7
uniprot id: A0A8B8RFV7
uniprot id: A0A8B8RFW3
uniprot id: A0A8B8RHT8
uniprot id: A0A8B8RIB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

419612:F8
gene id: 419612:F8
uniprot id: A0A8B8SMW5
uniprot id: A0A8B8SP76
uniprot id: A0A8B8SQ45
names: Similarity
messages: Belongs to the multicopper oxidase family.

419612:ATP2C1
gene id: 419612:ATP2C1
uniprot id: A0A8B7KEW5
uniprot id: A0A8B7KH24
uniprot id: A0A8B8TTI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:HSPB7
gene id: 419612:HSPB7
uniprot id: A0A8B8UA57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Nucleus

419612:DSG2
gene id: 419612:DSG2
uniprot id: A0A8B8RYN2
uniprot id: A0A8B8S014
uniprot id: A0A8B8S046
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: desmosome

419612:MCM6
gene id: 419612:MCM6
uniprot id: A0A8B6Y7N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

419612:TUBB6
gene id: 419612:TUBB6
uniprot id: A0A8B8S071
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

419612:TMPRSS13
gene id: 419612:TMPRSS13
uniprot id: A0A8B8SE84
uniprot id: A0A8B8SE92
uniprot id: A0A8B8SFF1
uniprot id: A0A8B8SFI4
uniprot id: A0A8B8SGS2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:DMRTC1B
gene id: 419612:DMRTC1B
uniprot id: A0A8B8SL99
names: Similarity
messages: Belongs to the DMRT family.

419612:CCNQ
gene id: 419612:CCNQ
uniprot id: A0A8B8SKX5
uniprot id: A0A8B8SN76
names: Similarity
messages: Belongs to the cyclin family. Cyclin-like FAM58 subfamily.

419612:LOC102521565
gene id: 419612:LOC102521565
uniprot id: S9W6E5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:LOC102524511
gene id: 419612:LOC102524511
uniprot id: A0A8B8SM04
uniprot id: A0A8B8SM05
uniprot id: A0A8B8SM09
uniprot id: A0A8B8SM10
uniprot id: A0A8B8SN24
uniprot id: A0A8B8SN29
uniprot id: A0A8B8SNC9
uniprot id: A0A8B8SND4
uniprot id: A0A8B8SP67
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

419612:DHDH
gene id: 419612:DHDH
uniprot id: A0A8B6Y9Q0
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

419612:UNC13A
gene id: 419612:UNC13A
uniprot id: A0A8B8RTA8
uniprot id: A0A8B8RTA9
uniprot id: A0A8B8RU96
uniprot id: A0A8B8RUX5
uniprot id: A0A8B8RV82
names: Subcellular Location Annotation
messages: Cytoplasm

419612:GPR171
gene id: 419612:GPR171
uniprot id: A0A8B7KEY9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:TACC3
gene id: 419612:TACC3
uniprot id: A0A8B8U0W8
uniprot id: A0A8B8U0X2
uniprot id: A0A8B8U0Y5
uniprot id: A0A8B8U0Z0
uniprot id: A0A8B8U0Z5
uniprot id: A0A8B8U1Y5
uniprot id: A0A8B8U298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

419612:TNIP2
gene id: 419612:TNIP2
uniprot id: A0A8B8U2D1
uniprot id: A0A8B8U2E1
uniprot id: A0A8B8U3A9
uniprot id: A0A8B8U3B8
uniprot id: A0A8B8U3D3
names: Subcellular Location Annotation
messages: Cytoplasm

419612:SLC25A42
gene id: 419612:SLC25A42
uniprot id: A0A8B8RSZ6
uniprot id: A0A8B8RTX7
uniprot id: A0A8B8RUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:SEC24D
gene id: 419612:SEC24D
uniprot id: A0A8B8RM40
uniprot id: A0A8B8RML0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

419612:LARS1
gene id: 419612:LARS1
uniprot id: A0A8B7K8C5
uniprot id: A0A8B8SS04
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

419612:TMEM178A
gene id: 419612:TMEM178A
uniprot id: A0A8B8UFA1
uniprot id: A0A8B8UG11
uniprot id: A0A8B8UG25
names: Similarity
messages: Belongs to the TMEM178 family.

419612:UHRF2
gene id: 419612:UHRF2
uniprot id: A0A8B8SU12
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

419612:TSSK6
gene id: 419612:TSSK6
uniprot id: A0A8B8RUJ9
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:CA7
gene id: 419612:CA7
uniprot id: A0A8B8TQE0
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

419612:KCNE4
gene id: 419612:KCNE4
uniprot id: A0A8B6YHT8
uniprot id: S9XWK5
names: Similarity
messages: Belongs to the potassium channel KCNE family.

419612:GADD45GIP1
gene id: 419612:GADD45GIP1
uniprot id: A0A8B6Y7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
messages: Belongs to the mitochondrion-specific ribosomal protein mL64 family.
messages: Mitochondrion
messages: Nucleus

419612:RASGRP4
gene id: 419612:RASGRP4
uniprot id: A0A8B7K7K2
uniprot id: A0A8B8TIC9
uniprot id: A0A8B8TIG7
uniprot id: A0A8B8TJL9
names: Similarity
messages: Belongs to the RASGRP family.

419612:SLC7A14
gene id: 419612:SLC7A14
uniprot id: A0A8B8TDK4
uniprot id: S9WIW0
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102510491
gene id: 419612:LOC102510491
uniprot id: S9WIA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102507671
gene id: 419612:LOC102507671
uniprot id: A0A8B8SG65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MRPL30
gene id: 419612:MRPL30
uniprot id: A0A8B6YQE3
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

419612:MTX3
gene id: 419612:MTX3
uniprot id: A0A8B8SMC2
uniprot id: A0A8B8SMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

419612:TRIP13
gene id: 419612:TRIP13
uniprot id: A0A8B8S4W2
uniprot id: A0A8B8S6B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.
messages: Specifically interacts with the ligand binding domain of the thyroid receptor (TR). This interaction does not require the presence of thyroid hormone for its interaction. Interacts with proteasome subunit PSMA8; to participate in meiosis progression during spermatogenesis.

419612:TGIF2LX
gene id: 419612:TGIF2LX
uniprot id: S9WDT2
names: Subcellular Location Annotation
messages: Nucleus

419612:SPRTN
gene id: 419612:SPRTN
uniprot id: A0A8B6YEU9
uniprot id: A0A8B7K9K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

419612:PRDX6
gene id: 419612:PRDX6
uniprot id: A0A8B8RQI7
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

419612:GPD1
gene id: 419612:GPD1
uniprot id: A0A8B6YCY1
uniprot id: A0A8B7K5L2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

419612:LOC102512507
gene id: 419612:LOC102512507
uniprot id: A0A8B6YAH7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CDK5RAP2
gene id: 419612:CDK5RAP2
uniprot id: A0A8B8SVU3
uniprot id: A0A8B8SW35
uniprot id: A0A8B8SW40
uniprot id: A0A8B8SW47
uniprot id: A0A8B8SWJ5
uniprot id: A0A8B8SWK0
uniprot id: A0A8B8SX69
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: centrosome

419612:SSH3
gene id: 419612:SSH3
uniprot id: A0A8B8TU86
uniprot id: A0A8B8TVB8
uniprot id: A0A8B8TVG7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

419612:MAPK8
gene id: 419612:MAPK8
uniprot id: A0A8B8TZ13
uniprot id: A0A8B8U019
uniprot id: A0A8B8U0C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

419612:PDS5B
gene id: 419612:PDS5B
uniprot id: A0A8B8UC98
uniprot id: A0A8B8UC99
uniprot id: A0A8B8UCA3
uniprot id: A0A8B8UCZ8
uniprot id: A0A8B8UD03
uniprot id: A0A8B8UD32
uniprot id: A0A8B8UDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDS5 family.
messages: Nucleus

419612:LOC102508890
gene id: 419612:LOC102508890
uniprot id: A0A8B8U8B4
uniprot id: A0A8B8U8B6
uniprot id: A0A8B8U959
uniprot id: A0A8B8U9B2
uniprot id: A0A8B8U9H3
names: Subcellular Location Annotation
messages: Membrane

419612:POP4
gene id: 419612:POP4
uniprot id: A0A8B6YHC6
uniprot id: A0A8B7KC63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

419612:CDC25C
gene id: 419612:CDC25C
uniprot id: A0A8B8SRE3
uniprot id: A0A8B8SRF0
uniprot id: A0A8B8SS44
uniprot id: A0A8B8SSH5
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

419612:CPB1
gene id: 419612:CPB1
uniprot id: S9WS84
names: Similarity
messages: Belongs to the peptidase M14 family.

419612:FABP7
gene id: 419612:FABP7
uniprot id: A0A8B6YJS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

419612:ZNF703
gene id: 419612:ZNF703
uniprot id: A0A8B7K916
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

419612:TTC3
gene id: 419612:TTC3
uniprot id: A0A8B7KBR8
uniprot id: A0A8B7KBS5
uniprot id: A0A8B8S0R3
uniprot id: A0A8B8S2B5
uniprot id: A0A8B8S2Z1
names: Subcellular Location Annotation
messages: Cytoplasm

419612:NPW
gene id: 419612:NPW
uniprot id: A0A8B8RG55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

419612:POLR1C
gene id: 419612:POLR1C
uniprot id: A0A8B6YM70
uniprot id: A0A8B8RPE5
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

419612:HOXD11
gene id: 419612:HOXD11
uniprot id: A0A8B8T0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

419612:MAPKAPK3
gene id: 419612:MAPKAPK3
uniprot id: A0A8B8R8J5
uniprot id: A0A8B8R8P3
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:P3H1
gene id: 419612:P3H1
uniprot id: A0A8B6Y6S8
uniprot id: A0A8B8U6I3
names: Similarity
messages: Belongs to the leprecan family.

419612:TMEM176B
gene id: 419612:TMEM176B
uniprot id: A0A8B8TA20
names: Similarity
messages: Belongs to the TMEM176 family.

419612:DTX1
gene id: 419612:DTX1
uniprot id: A0A8B8SE68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

419612:TMEM258
gene id: 419612:TMEM258
uniprot id: A0A8B6Y6X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

419612:PPP1R15A
gene id: 419612:PPP1R15A
uniprot id: A0A8B8TH17
names: Similarity
messages: Belongs to the PPP1R15 family.

419612:LOC102519318
gene id: 419612:LOC102519318
uniprot id: A0A8B7K9M8
names: Subcellular Location Annotation
messages: Nucleus

419612:A2ML1
gene id: 419612:A2ML1
uniprot id: A0A8B8SIQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

419612:POLG2
gene id: 419612:POLG2
uniprot id: A0A8B6Y8Y1
uniprot id: A0A8B7K5C6
names: Subcellular Location Annotation
messages: Mitochondrion

419612:PITX2
gene id: 419612:PITX2
uniprot id: A0A8B6YLD4
uniprot id: A0A8B8RIJ3
uniprot id: S9XWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

419612:MRPL21
gene id: 419612:MRPL21
uniprot id: A0A8B6Y5D0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL21 family.

419612:ATL3
gene id: 419612:ATL3
uniprot id: A0A8B8TTE7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

419612:C12H12orf75
gene id: 419612:C12H12orf75
uniprot id: A0A8B8U408
names: Similarity
messages: Belongs to the OCC1 family.

419612:ATP5MG
gene id: 419612:ATP5MG
uniprot id: A0A8B6Y7R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

419612:LOC102524260
gene id: 419612:LOC102524260
uniprot id: A0A8B8TWZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC116666378
gene id: 419612:LOC116666378
uniprot id: A0A8B8TQM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ZGPAT
gene id: 419612:ZGPAT
uniprot id: A0A8B8RHR2
uniprot id: S9XI15
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CHD4/Mi-2; the interaction is direct.
messages: Nucleus

419612:CITED1
gene id: 419612:CITED1
uniprot id: A0A8B8SL55
uniprot id: A0A8B8SL58
uniprot id: A0A8B8SM99
uniprot id: A0A8B8SMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

419612:SLC15A3
gene id: 419612:SLC15A3
uniprot id: A0A8B8TU19
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

419612:LOC102523139
gene id: 419612:LOC102523139
uniprot id: A0A8B6YAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:HEXIM2
gene id: 419612:HEXIM2
uniprot id: A0A8B8R5M7
uniprot id: S9YQM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

419612:CNOT11
gene id: 419612:CNOT11
uniprot id: A0A8B6YLQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

419612:NBN
gene id: 419612:NBN
uniprot id: A0A8B8S7I7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

419612:TMPRSS2
gene id: 419612:TMPRSS2
uniprot id: A0A8B8RKP8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102515744
gene id: 419612:LOC102515744
uniprot id: A0A8B6YBC9
uniprot id: A0A8B7K5Y6
uniprot id: A0A8B8RKV2
uniprot id: A0A8B8RKV4
uniprot id: A0A8B8RL54
uniprot id: A0A8B8RL57
uniprot id: A0A8B8RML7
uniprot id: A0A8B8RMM1
uniprot id: A0A8B8RN25
uniprot id: A0A8B8RN29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

419612:LOC102514442
gene id: 419612:LOC102514442
uniprot id: A0A8B8TVX1
uniprot id: A0A8B8TVX4
uniprot id: A0A8B8TVX6
uniprot id: A0A8B8TVX7
uniprot id: A0A8B8TX01
uniprot id: A0A8B8TXA4
uniprot id: A0A8B8TXA9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SLC27A3
gene id: 419612:SLC27A3
uniprot id: A0A8B8RQ90
uniprot id: A0A8B8RQT3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

419612:HDAC3
gene id: 419612:HDAC3
uniprot id: A0A8B6YF19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

419612:IL1RAPL2
gene id: 419612:IL1RAPL2
uniprot id: A0A8B8SN15
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

419612:ASPA
gene id: 419612:ASPA
uniprot id: A0A8B8UH55
uniprot id: A0A8B8UHR1
uniprot id: A0A8B8UHR6
uniprot id: A0A8B8UIG7
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

419612:LOC102504950
gene id: 419612:LOC102504950
uniprot id: A0A8B6Y5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:OAZ3
gene id: 419612:OAZ3
uniprot id: A0A8B6X0G0
names: Similarity
messages: Belongs to the ODC antizyme family.

419612:LOC116667233
gene id: 419612:LOC116667233
uniprot id: A0A8B8TZ10
uniprot id: A0A8B8U0B9
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

419612:LSM6
gene id: 419612:LSM6
uniprot id: A0A8B8RSV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

419612:DEUP1
gene id: 419612:DEUP1
uniprot id: A0A8B8TPN5
uniprot id: A0A8B8TPP9
uniprot id: A0A8B8TQC8
uniprot id: A0A8B8TQU4
names: Similarity
messages: Belongs to the CEP63 family.

419612:CTNND1
gene id: 419612:CTNND1
uniprot id: A0A8B7K5H5
uniprot id: A0A8B7K5X1
uniprot id: A0A8B8TQR2
uniprot id: A0A8B8TQR9
uniprot id: A0A8B8TRH7
uniprot id: A0A8B8TRV6
names: Similarity
messages: Belongs to the beta-catenin family.

419612:TEF
gene id: 419612:TEF
uniprot id: A0A8B8U188
uniprot id: A0A8B8U1W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

419612:PYCR2
gene id: 419612:PYCR2
uniprot id: A0A8B6YII5
uniprot id: A0A8B7KC70
uniprot id: A0A8B7KEA8
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

419612:PRPF19
gene id: 419612:PRPF19
uniprot id: S9XR00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

419612:SET
gene id: 419612:SET
uniprot id: A0A8B8SWU1
uniprot id: A0A8B8SXA4
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

419612:POPDC2
gene id: 419612:POPDC2
uniprot id: A0A8B6YKL6
uniprot id: A0A8B6YLZ2
names: Similarity
messages: Belongs to the popeye family.

419612:EIF2S2
gene id: 419612:EIF2S2
uniprot id: A0A8B8RJJ6
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

419612:OSBP2
gene id: 419612:OSBP2
uniprot id: A0A8B8SB12
uniprot id: A0A8B8SC72
uniprot id: A0A8B8SCC5
uniprot id: A0A8B8SDH0
names: Similarity
messages: Belongs to the OSBP family.

419612:GBX2
gene id: 419612:GBX2
uniprot id: A0A8B8T3A3
names: Subcellular Location Annotation
messages: Nucleus

419612:TOMM7
gene id: 419612:TOMM7
uniprot id: A0A8B8TC86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

419612:CLDN19
gene id: 419612:CLDN19
uniprot id: A0A8B6Y506
uniprot id: A0A8B8U5L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

419612:LRRC8B
gene id: 419612:LRRC8B
uniprot id: A0A8B8TLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

419612:CFAP157
gene id: 419612:CFAP157
uniprot id: A0A8B8SX33
names: Similarity
messages: Belongs to the CFAP157 family.

419612:FOXL2
gene id: 419612:FOXL2
uniprot id: A0A8B8TMI7
names: Subcellular Location Annotation
messages: Nucleus

419612:MED26
gene id: 419612:MED26
uniprot id: A0A8B7KGR4
uniprot id: A0A8B8RTG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

419612:SAXO2
gene id: 419612:SAXO2
uniprot id: A0A8B7KF41
names: Similarity
messages: Belongs to the FAM154 family.

419612:ZC3H12C
gene id: 419612:ZC3H12C
uniprot id: A0A8B8SEH8
uniprot id: A0A8B8SFN8
uniprot id: A0A8B8SFR8
names: Similarity
messages: Belongs to the ZC3H12 family.

419612:SLC29A3
gene id: 419612:SLC29A3
uniprot id: A0A8B8S764
uniprot id: A0A8B8S8N2
uniprot id: A0A8B8S9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

419612:LOC116661790
gene id: 419612:LOC116661790
uniprot id: A0A8B8SK60
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:POU2F3
gene id: 419612:POU2F3
uniprot id: A0A8B8SDE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

419612:TSSK1B
gene id: 419612:TSSK1B
uniprot id: A0A8B7KAL8
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:SLCO1A2
gene id: 419612:SLCO1A2
uniprot id: A0A8B7KBU3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:RNF43
gene id: 419612:RNF43
uniprot id: A0A8B7K7N9
uniprot id: A0A8B8UIB7
uniprot id: A0A8B8UIT9
uniprot id: A0A8B8UIV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

419612:POU2F2
gene id: 419612:POU2F2
uniprot id: A0A8B8THU5
uniprot id: A0A8B8THV0
uniprot id: A0A8B8THW0
uniprot id: A0A8B8THW8
uniprot id: A0A8B8THX2
uniprot id: A0A8B8THX5
uniprot id: A0A8B8THX7
uniprot id: A0A8B8THX8
uniprot id: A0A8B8THX9
uniprot id: A0A8B8THY2
uniprot id: A0A8B8THY3
uniprot id: A0A8B8THY6
uniprot id: A0A8B8THY7
uniprot id: A0A8B8TJ40
uniprot id: A0A8B8TJ46
uniprot id: A0A8B8TJ49
uniprot id: A0A8B8TJ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.

419612:NIPSNAP2
gene id: 419612:NIPSNAP2
uniprot id: A0A8B8RE53
uniprot id: A0A8B8RE62
uniprot id: A0A8B8RG71
uniprot id: A0A8B8RGN5
names: Similarity
messages: Belongs to the NipSnap family.

419612:IL6R
gene id: 419612:IL6R
uniprot id: A0A8B8RRT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.
messages: Membrane

419612:LRWD1
gene id: 419612:LRWD1
uniprot id: A0A8B8RBZ8
uniprot id: A0A8B8RBZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

419612:LOC102513958
gene id: 419612:LOC102513958
uniprot id: S9YCH0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

419612:BZW2
gene id: 419612:BZW2
uniprot id: A0A8B6YQC5
uniprot id: A0A8B8TD96
names: Similarity
messages: Belongs to the BZW family.

419612:CLDN2
gene id: 419612:CLDN2
uniprot id: S9WCX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

419612:ERCC3
gene id: 419612:ERCC3
uniprot id: A0A8B8SZM2
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

419612:ADGRE2
gene id: 419612:ADGRE2
uniprot id: A0A8B8RTN3
uniprot id: A0A8B8RTN5
uniprot id: A0A8B8RUN4
uniprot id: A0A8B8RV89
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:MUSK
gene id: 419612:MUSK
uniprot id: A0A8B8SVE2
uniprot id: A0A8B8SVP0
uniprot id: A0A8B8SVQ2
uniprot id: A0A8B8SW62
uniprot id: A0A8B8SWT8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:TBL3
gene id: 419612:TBL3
uniprot id: A0A8B8RDI2
uniprot id: A0A8B8RG27
names: Subcellular Location Annotation
messages: nucleolus

419612:SCN1B
gene id: 419612:SCN1B
uniprot id: A0A8B8TP32
names: Subcellular Location Annotation
messages: Membrane

419612:TSPAN16
gene id: 419612:TSPAN16
uniprot id: A0A8B8RY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:STRN3
gene id: 419612:STRN3
uniprot id: A0A8B8T626
uniprot id: A0A8B8T652
uniprot id: A0A8B8T6E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

419612:LOC116669192
gene id: 419612:LOC116669192
uniprot id: A0A8B8UHN3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102508620
gene id: 419612:LOC102508620
uniprot id: A0A8B6YFE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CCR6
gene id: 419612:CCR6
uniprot id: A0A8B8TG70
uniprot id: T0M660
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:TM7SF3
gene id: 419612:TM7SF3
uniprot id: A0A8B8SFT8
uniprot id: A0A8B8SFW3
names: Subcellular Location Annotation
messages: Membrane

419612:KRT18
gene id: 419612:KRT18
uniprot id: A0A8B6YHG5
names: Similarity
messages: Belongs to the intermediate filament family.

419612:SLC25A34
gene id: 419612:SLC25A34
uniprot id: A0A8B8UA02
uniprot id: A0A8B8UA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:TSEN2
gene id: 419612:TSEN2
uniprot id: A0A8B8RCC7
uniprot id: A0A8B8RCD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

419612:LOC102508741
gene id: 419612:LOC102508741
uniprot id: A0A8B7KF01
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

419612:CHD8
gene id: 419612:CHD8
uniprot id: A0A8B7KDZ5
uniprot id: A0A8B7KE78
uniprot id: A0A8B8T5I7
uniprot id: A0A8B8T5L9
uniprot id: A0A8B8T686
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Belongs to the SNF2/RAD54 helicase family. CHD8 subfamily.
messages: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF. Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity. Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription.
messages: Interacts with p53/TP53, histone H1, CTNNB1, CTCF and PIAS3. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with CHD7. Interacts with FAM124B.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Sumoylated.

419612:PIM3
gene id: 419612:PIM3
uniprot id: A0A8B8U2I2
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

419612:GPR4
gene id: 419612:GPR4
uniprot id: S9YLT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:METTL3
gene id: 419612:METTL3
uniprot id: A0A8B6YPN9
names: Similarity
messages: Belongs to the MT-A70-like family.

419612:AURKB
gene id: 419612:AURKB
uniprot id: A0A8B6Y8K1
uniprot id: A0A8B6Y8W7
uniprot id: A0A8B7K565
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

419612:ABRACL
gene id: 419612:ABRACL
uniprot id: A0A8B8TFB8
uniprot id: T0MJZ0
names: Similarity
messages: Belongs to the costars family.

419612:HSPA1L
gene id: 419612:HSPA1L
uniprot id: A0A8B8RKV9
uniprot id: S9XAK2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

419612:DLX1
gene id: 419612:DLX1
uniprot id: A0A8B6YJQ0
names: Subcellular Location Annotation
messages: Nucleus

419612:SLC35F2
gene id: 419612:SLC35F2
uniprot id: A0A8B8SDB7
uniprot id: A0A8B8SFV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

419612:GJC1
gene id: 419612:GJC1
uniprot id: S9YQP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with CNST.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

419612:ESCO1
gene id: 419612:ESCO1
uniprot id: A0A8B8S0S5
names: Subcellular Location Annotation
messages: Nucleus

419612:VWF
gene id: 419612:VWF
uniprot id: A0A8B8SGK2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
messages: Multimeric. Interacts with F8.
messages: Secreted
messages: extracellular matrix

419612:LCN2
gene id: 419612:LCN2
uniprot id: A0A8B6YD96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

419612:MYOC
gene id: 419612:MYOC
uniprot id: A0A8B6YLY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:TAF4B
gene id: 419612:TAF4B
uniprot id: A0A8B6YHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

419612:LOC106729860
gene id: 419612:LOC106729860
uniprot id: A0A8B8TWU0
names: Similarity
messages: Belongs to the PPDPF family.

419612:KCND2
gene id: 419612:KCND2
uniprot id: A0A8B6YP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite
messages: dendritic spine

419612:SLC25A44
gene id: 419612:SLC25A44
uniprot id: S9XLX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:CHN1
gene id: 419612:CHN1
uniprot id: A0A8B8T014
names: Function
messages: GTPase-activating protein for p21-rac.

419612:CCNG1
gene id: 419612:CCNG1
uniprot id: A0A8B8RTT1
names: Similarity
messages: Belongs to the cyclin family.

419612:PRMT7
gene id: 419612:PRMT7
uniprot id: A0A8B6YFP7
uniprot id: A0A8B7K7J5
uniprot id: A0A8B8TK24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

419612:CACTIN
gene id: 419612:CACTIN
uniprot id: A0A8B8RWB2
names: Similarity
messages: Belongs to the CACTIN family.

419612:PIGU
gene id: 419612:PIGU
uniprot id: A0A8B6YMQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:KRT24
gene id: 419612:KRT24
uniprot id: A0A8B8UHG2
names: Similarity
messages: Belongs to the intermediate filament family.

419612:SLC9A8
gene id: 419612:SLC9A8
uniprot id: A0A8B6Y778
uniprot id: A0A8B8RH05
uniprot id: A0A8B8RH81
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

419612:LCK
gene id: 419612:LCK
uniprot id: A0A8B6Y804
uniprot id: A0A8B8UC46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

419612:FHL5
gene id: 419612:FHL5
uniprot id: S9XVE1
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

419612:PEMT
gene id: 419612:PEMT
uniprot id: A0A8B6Y6V0
uniprot id: A0A8B8UKH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

419612:CAMK2D
gene id: 419612:CAMK2D
uniprot id: A0A8B8RJL3
uniprot id: A0A8B8RJM3
uniprot id: A0A8B8RJP8
uniprot id: A0A8B8RJQ2
uniprot id: A0A8B8RJY0
uniprot id: A0A8B8RK00
uniprot id: A0A8B8RLD7
uniprot id: A0A8B8RLG6
uniprot id: A0A8B8RLI6
uniprot id: A0A8B8RLJ1
uniprot id: A0A8B8RLU2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

419612:SRD5A1
gene id: 419612:SRD5A1
uniprot id: A0A8B6YPJ6
uniprot id: A0A8B8S660
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane
messages: Microsome membrane

419612:GEMIN2
gene id: 419612:GEMIN2
uniprot id: A0A8B6YM76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

419612:ACTRT2
gene id: 419612:ACTRT2
uniprot id: S9XF69
names: Similarity
messages: Belongs to the actin family.

419612:TEX261
gene id: 419612:TEX261
uniprot id: A0A8B8UGG6
uniprot id: A0A8B8UH47
uniprot id: A0A8B8UHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

419612:LOC102512707
gene id: 419612:LOC102512707
uniprot id: A0A8B6YMR7
uniprot id: A0A8B8RJG9
uniprot id: A0A8B8RJT7
names: Similarity
messages: Belongs to the copine family.

419612:LOC116662086
gene id: 419612:LOC116662086
uniprot id: A0A8B8SM14
uniprot id: A0A8B8SM19
uniprot id: A0A8B8SN34
uniprot id: A0A8B8SND8
uniprot id: A0A8B8SNE3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

419612:SLC2A4
gene id: 419612:SLC2A4
uniprot id: A0A8B6Y809
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Membrane
messages: perinuclear region

419612:PROM1
gene id: 419612:PROM1
uniprot id: A0A8B8U6T6
uniprot id: A0A8B8U6T9
uniprot id: A0A8B8U7P6
uniprot id: A0A8B8U7T0
uniprot id: A0A8B8U7T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

419612:ZDHHC23
gene id: 419612:ZDHHC23
uniprot id: A0A8B8SZL2
uniprot id: A0A8B8T027
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

419612:ZNF165
gene id: 419612:ZNF165
uniprot id: A0A8B8RMU4
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102506764
gene id: 419612:LOC102506764
uniprot id: A0A8B7K897
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TMTC1
gene id: 419612:TMTC1
uniprot id: A0A8B8SFQ2
uniprot id: A0A8B8SFQ4
uniprot id: A0A8B8SGU5
uniprot id: A0A8B8SGV0
uniprot id: A0A8B8SIA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

419612:ATAT1
gene id: 419612:ATAT1
uniprot id: A0A8B6YLK4
uniprot id: A0A8B6YLM6
uniprot id: A0A8B6YLT2
uniprot id: A0A8B6YQB6
uniprot id: A0A8B8RN45
uniprot id: A0A8B8RNG9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

419612:TEX13A
gene id: 419612:TEX13A
uniprot id: A0A8B8SQ94
names: Similarity
messages: Belongs to the TEX13 family.

419612:XPC
gene id: 419612:XPC
uniprot id: A0A8B8R9F3
uniprot id: A0A8B8R9F8
uniprot id: A0A8B8R9G4
uniprot id: A0A8B8R9K0
uniprot id: A0A8B8R9K4
uniprot id: A0A8B8RBL5
uniprot id: A0A8B8RC81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPC family.
messages: Nucleus

419612:DDOST
gene id: 419612:DDOST
uniprot id: A0A8B6YIP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

419612:LOC116661088
gene id: 419612:LOC116661088
uniprot id: A0A8B8SD88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ACAA2
gene id: 419612:ACAA2
uniprot id: A0A8B8S9A5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

419612:LOC102523259
gene id: 419612:LOC102523259
uniprot id: S9WTT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:WARS2
gene id: 419612:WARS2
uniprot id: A0A8B6YJ05
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

419612:CTSH
gene id: 419612:CTSH
uniprot id: A0A8B8S4S6
uniprot id: A0A8B8S6A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

419612:SERPINB11
gene id: 419612:SERPINB11
uniprot id: A0A8B6YMF9
names: Similarity
messages: Belongs to the serpin family.

419612:TYRP1
gene id: 419612:TYRP1
uniprot id: A0A8B7KFP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

419612:LOC102518999
gene id: 419612:LOC102518999
uniprot id: S9XAC1
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

419612:SLC16A3
gene id: 419612:SLC16A3
uniprot id: A0A8B8UKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

419612:NIT1
gene id: 419612:NIT1
uniprot id: A0A8B6Y9U1
uniprot id: A0A8B7KCN3
uniprot id: A0A8B7KDE8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

419612:LOC102510454
gene id: 419612:LOC102510454
uniprot id: A0A8B6YGP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LGSN
gene id: 419612:LGSN
uniprot id: A0A8B8TDR5
names: Similarity
messages: Belongs to the glutamine synthetase family.

419612:GSX2
gene id: 419612:GSX2
uniprot id: A0A8B8UG52
names: Subcellular Location Annotation
messages: Nucleus

419612:BICD1
gene id: 419612:BICD1
uniprot id: A0A8B6YMA3
uniprot id: A0A8B6YNS6
uniprot id: A0A8B7KF48
uniprot id: A0A8B8SF69
uniprot id: A0A8B8SF82
uniprot id: A0A8B8SGD9
uniprot id: A0A8B8SGG4
uniprot id: A0A8B8SHT0
names: Similarity
messages: Belongs to the BicD family.

419612:NEFM
gene id: 419612:NEFM
uniprot id: A0A8B8S947
uniprot id: A0A8B8SBF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: axon

419612:CSNK1G1
gene id: 419612:CSNK1G1
uniprot id: A0A8B6YEN8
uniprot id: A0A8B6YF11
uniprot id: A0A8B6YIR6
uniprot id: A0A8B8T3L1
uniprot id: A0A8B8T3L3
uniprot id: A0A8B8T3X7
uniprot id: A0A8B8T4D0
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

419612:RHBDL1
gene id: 419612:RHBDL1
uniprot id: A0A8B8REX2
uniprot id: A0A8B8REY4
uniprot id: A0A8B8RGW7
uniprot id: A0A8B8RHE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Membrane

419612:PPP6R1
gene id: 419612:PPP6R1
uniprot id: A0A8B8TMQ7
uniprot id: A0A8B8TMR8
uniprot id: A0A8B8TMS0
uniprot id: A0A8B8TMS2
uniprot id: A0A8B8TMS3
uniprot id: A0A8B8TMS7
uniprot id: A0A8B8TN79
uniprot id: A0A8B8TN88
uniprot id: A0A8B8TNY2
uniprot id: A0A8B8TNY5
names: Similarity
messages: Belongs to the SAPS family.

419612:NR2E3
gene id: 419612:NR2E3
uniprot id: A0A8B8S5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

419612:LOC116661734
gene id: 419612:LOC116661734
uniprot id: A0A8B8SIU0
names: Similarity
messages: Belongs to the NIBP family.

419612:SNRPB
gene id: 419612:SNRPB
uniprot id: A0A8B6YHY9
uniprot id: A0A8B8RKN1
uniprot id: A0A8B8RL37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

419612:SEC11C
gene id: 419612:SEC11C
uniprot id: A0A8B8S7V4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:DDX50
gene id: 419612:DDX50
uniprot id: A0A8B6YC60
uniprot id: A0A8B8TZP9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

419612:ZNF75D
gene id: 419612:ZNF75D
uniprot id: A0A8B6YL63
uniprot id: A0A8B8SKY6
names: Subcellular Location Annotation
messages: Nucleus

419612:TSC22D1
gene id: 419612:TSC22D1
uniprot id: A0A8B6YBP1
uniprot id: A0A8B7K4G8
uniprot id: A0A8B8UCJ2
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

419612:PGM2L1
gene id: 419612:PGM2L1
uniprot id: A0A8B6YDV5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

419612:LOC102506206
gene id: 419612:LOC102506206
uniprot id: A0A8B7K6L0
uniprot id: A0A8B8RGM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:UNC119B
gene id: 419612:UNC119B
uniprot id: A0A8B8SCD3
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

419612:CHRM4
gene id: 419612:CHRM4
uniprot id: S9X1E1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

419612:MYG1
gene id: 419612:MYG1
uniprot id: A0A8B8U379
names: Similarity
messages: Belongs to the MYG1 family.

419612:LOC106730709
gene id: 419612:LOC106730709
uniprot id: A0A8B8SVG2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

419612:TMEM225B
gene id: 419612:TMEM225B
uniprot id: A0A8B7KGU3
uniprot id: A0A8B8RCG0
uniprot id: A0A8B8REZ7
names: Subcellular Location Annotation
messages: Membrane

419612:SPOCK2
gene id: 419612:SPOCK2
uniprot id: A0A8B6YG67
uniprot id: S9WZK2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:PROZ
gene id: 419612:PROZ
uniprot id: A0A8B8UD17
uniprot id: A0A8B8UED4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:TSTA3
gene id: 419612:TSTA3
uniprot id: A0A8B8S070
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

419612:ADRA1B
gene id: 419612:ADRA1B
uniprot id: A0A8B8STI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

419612:NRDE2
gene id: 419612:NRDE2
uniprot id: A0A8B8T9N2
names: Similarity
messages: Belongs to the NRDE2 family.

419612:SLC39A6
gene id: 419612:SLC39A6
uniprot id: A0A8B8S0D4
names: Subcellular Location Annotation
messages: Membrane

419612:GATA4
gene id: 419612:GATA4
uniprot id: A0A8B8SA48
names: Subcellular Location Annotation
messages: Nucleus

419612:FAM214B
gene id: 419612:FAM214B
uniprot id: A0A8B6YJK2
uniprot id: A0A8B8SW61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

419612:LOC102516599
gene id: 419612:LOC102516599
uniprot id: A0A8B7K6F5
uniprot id: A0A8B8T512
uniprot id: A0A8B8T5B8
uniprot id: A0A8B8T5Q2
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

419612:TEKT1
gene id: 419612:TEKT1
uniprot id: A0A8B7K9D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

419612:EIF3A
gene id: 419612:EIF3A
uniprot id: A0A8B8TXY8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3L and EIF3K. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with EIF4G1. Also interacts with KRT7 and PIWIL2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.

419612:LOC102521357
gene id: 419612:LOC102521357
uniprot id: A0A8B8T9L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FAT4
gene id: 419612:FAT4
uniprot id: A0A8B8RP73
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SNX2
gene id: 419612:SNX2
uniprot id: A0A8B6YKS7
uniprot id: A0A8B8SSN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

419612:ANO9
gene id: 419612:ANO9
uniprot id: A0A8B8TVE6
uniprot id: A0A8B8TWP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:RPL3
gene id: 419612:RPL3
uniprot id: A0A8B6YBH1
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

419612:ZDHHC17
gene id: 419612:ZDHHC17
uniprot id: A0A8B6YPU7
uniprot id: A0A8B7KEE0
uniprot id: A0A8B8U5T1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

419612:LOC102507900
gene id: 419612:LOC102507900
uniprot id: A0A8B6YNF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TSPYL5
gene id: 419612:TSPYL5
uniprot id: A0A8B8RZP4
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

419612:ITGB2
gene id: 419612:ITGB2
uniprot id: A0A8B8TXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

419612:CD3G
gene id: 419612:CD3G
uniprot id: A0A8B8SDN7
uniprot id: A0A8B8SG79
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Membrane
messages: The TCR-CD3 complex is composed of a CD3D/CD3E and a CD3G/CD3E heterodimers that preferentially associate with TCRalpha and TCRbeta, respectively, to form TCRalpha/CD3E/CD3G and TCRbeta/CD3G/CD3E trimers. In turn, the hexamer interacts with CD3Z homodimer to form the TCR-CD3 complex. Alternatively, TCRalpha and TCRbeta can be replaced by TCRgamma and TCRdelta.

419612:MAPK7
gene id: 419612:MAPK7
uniprot id: A0A8B8UK92
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

419612:TMPRSS9
gene id: 419612:TMPRSS9
uniprot id: A0A8B8RWX3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:ZNF503
gene id: 419612:ZNF503
uniprot id: A0A8B8U162
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

419612:LOC102518689
gene id: 419612:LOC102518689
uniprot id: A0A8B8RPJ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:OSM
gene id: 419612:OSM
uniprot id: S9YAK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIF/OSM family.
messages: Secreted

419612:LOC102514273
gene id: 419612:LOC102514273
uniprot id: A0A8B8TCM3
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

419612:LOC116665063
gene id: 419612:LOC116665063
uniprot id: A0A8B8TD73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

419612:RIPPLY2
gene id: 419612:RIPPLY2
uniprot id: A0A8B8TDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

419612:FBXO25
gene id: 419612:FBXO25
uniprot id: A0A8B8S2H9
uniprot id: A0A8B8S2I0
uniprot id: A0A8B8S2I3
uniprot id: A0A8B8S2I5
uniprot id: A0A8B8S3U6
uniprot id: A0A8B8S3V0
uniprot id: A0A8B8S3V4
uniprot id: A0A8B8S434
uniprot id: A0A8B8S438
uniprot id: A0A8B8S489
uniprot id: A0A8B8S495
uniprot id: A0A8B8S4A0
uniprot id: A0A8B8S4A5
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102507700
gene id: 419612:LOC102507700
uniprot id: S9YBH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:GPR141
gene id: 419612:GPR141
uniprot id: S9WJH8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:LOC102512112
gene id: 419612:LOC102512112
uniprot id: S9W7D9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ANK1
gene id: 419612:ANK1
uniprot id: A0A8B8S375
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

419612:RPL23
gene id: 419612:RPL23
uniprot id: A0A8B6YBU2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.

419612:TRMT61A
gene id: 419612:TRMT61A
uniprot id: A0A8B8T9V7
uniprot id: S9XJ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

419612:ZNF598
gene id: 419612:ZNF598
uniprot id: A0A8B8RDJ7
uniprot id: A0A8B8RDQ7
names: Similarity
messages: Belongs to the ZNF598/HEL2 family.

419612:LOC102505066
gene id: 419612:LOC102505066
uniprot id: A0A8B7KE92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FGD2
gene id: 419612:FGD2
uniprot id: A0A8B6YPM7
uniprot id: A0A8B8RLP8
uniprot id: A0A8B8RLQ3
uniprot id: A0A8B8RM00
uniprot id: A0A8B8RNG3
uniprot id: A0A8B8RNV9
names: Subcellular Location Annotation
messages: cytoskeleton

419612:RTBDN
gene id: 419612:RTBDN
uniprot id: A0A8B6Y7U1
names: Similarity
messages: Belongs to the folate receptor family.

419612:C5AR1
gene id: 419612:C5AR1
uniprot id: A0A8B7K6B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

419612:FZD2
gene id: 419612:FZD2
uniprot id: A0A8B7KDL4
uniprot id: A0A8B8R5I9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC116657190
gene id: 419612:LOC116657190
uniprot id: A0A8B8RCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

419612:ETF1
gene id: 419612:ETF1
uniprot id: A0A8B8SS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

419612:LOC102507249
gene id: 419612:LOC102507249
uniprot id: A0A8B8TZS8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

419612:ELOVL4
gene id: 419612:ELOVL4
uniprot id: A0A8B6YH01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Oligomer.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

419612:SLC15A2
gene id: 419612:SLC15A2
uniprot id: A0A8B6YK23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

419612:HYI
gene id: 419612:HYI
uniprot id: A0A8B8U6X8
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

419612:MFSD1
gene id: 419612:MFSD1
uniprot id: A0A8B6YKH7
uniprot id: A0A8B7KFN5
names: Subcellular Location Annotation
messages: Membrane

419612:BDH2
gene id: 419612:BDH2
uniprot id: A0A8B8RFI9
uniprot id: A0A8B8RFK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:TRPC3
gene id: 419612:TRPC3
uniprot id: A0A8B8RL93
uniprot id: A0A8B8RL97
uniprot id: A0A8B8RLI8
uniprot id: A0A8B8RLJ3
uniprot id: A0A8B8RNH2
names: Subcellular Location Annotation
messages: Membrane

419612:INPP5J
gene id: 419612:INPP5J
uniprot id: A0A8B8SAZ6
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

419612:CTNNBIP1
gene id: 419612:CTNNBIP1
uniprot id: A0A8B8U8X2
names: Similarity
messages: Belongs to the CTNNBIP1 family.

419612:PIGK
gene id: 419612:PIGK
uniprot id: A0A8B6YIV5
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.

419612:CATSPERD
gene id: 419612:CATSPERD
uniprot id: A0A8B6YCT5
uniprot id: A0A8B8RWN0
names: Similarity
messages: Belongs to the CATSPERD family.

419612:ANHX
gene id: 419612:ANHX
uniprot id: A0A8B8SE01
uniprot id: A0A8B8SE53
uniprot id: A0A8B8SFB7
names: Subcellular Location Annotation
messages: Nucleus

419612:XPO6
gene id: 419612:XPO6
uniprot id: A0A8B8RET6
uniprot id: A0A8B8RF02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

419612:KCNJ6
gene id: 419612:KCNJ6
uniprot id: A0A8B8RYM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

419612:PLPBP
gene id: 419612:PLPBP
uniprot id: A0A8B6YEK3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

419612:LOC116656726
gene id: 419612:LOC116656726
uniprot id: A0A8B8R3S6
uniprot id: A0A8B8R6G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

419612:SKOR1
gene id: 419612:SKOR1
uniprot id: A0A8B8T3B2
names: Similarity
messages: Belongs to the SKI family.

419612:SOD1
gene id: 419612:SOD1
uniprot id: A0A8B8SSA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

419612:MEA1
gene id: 419612:MEA1
uniprot id: A0A8B7KDT7
uniprot id: A0A8B7KFY8
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

419612:LOC102505697
gene id: 419612:LOC102505697
uniprot id: A0A8B6YP12
names: Similarity
messages: Belongs to the cytochrome b5 family.

419612:IL10RB
gene id: 419612:IL10RB
uniprot id: A0A8B8SJ19
uniprot id: A0A8B8SJ55
names: Subcellular Location Annotation
messages: Membrane

419612:MAP3K21
gene id: 419612:MAP3K21
uniprot id: A0A8B8TZG2
uniprot id: A0A8B8TZM6
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

419612:SLC11A1
gene id: 419612:SLC11A1
uniprot id: A0A8B6YHF2
uniprot id: A0A8B8T225
uniprot id: A0A8B8T2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Macrophage-specific antiporter that fluxes metal ions in either direction against a proton gradient. Localized to late endosomal lysosomal membranes, delivers bivalent cations from the cytosol into these acidic compartments where they may directly affect antimicrobial activity. Involved in iron metabolism and host natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

419612:YPEL3
gene id: 419612:YPEL3
uniprot id: A0A8B6YJ29
uniprot id: A0A8B8RGL2
names: Similarity
messages: Belongs to the yippee family.

419612:FGF4
gene id: 419612:FGF4
uniprot id: A0A8B8TWR2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

419612:DPCD
gene id: 419612:DPCD
uniprot id: A0A8B6YHW4
uniprot id: A0A8B7KAY2
uniprot id: A0A8B8TXB0
uniprot id: A0A8B8TXB2
uniprot id: A0A8B8TYD7
names: Similarity
messages: Belongs to the DPCD family.

419612:LOC102510151
gene id: 419612:LOC102510151
uniprot id: A0A8B8SFZ7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:NT5DC3
gene id: 419612:NT5DC3
uniprot id: A0A8B8U599
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

419612:TRAPPC9
gene id: 419612:TRAPPC9
uniprot id: A0A8B8S0U3
uniprot id: A0A8B8S262
uniprot id: A0A8B8S2F8
names: Similarity
messages: Belongs to the NIBP family.

419612:LOC102509655
gene id: 419612:LOC102509655
uniprot id: A0A8B8TRN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

419612:JPH1
gene id: 419612:JPH1
uniprot id: A0A8B8S8U1
uniprot id: A0A8B8S9K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

419612:ISCU
gene id: 419612:ISCU
uniprot id: A0A8B8SDA2
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Mitochondrial scaffold protein, of the core iron-sulfur cluster (ISC) assembly complex, that provides the structural architecture on which the [2Fe-2S] clusters are assembled. The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis. This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner. Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly. Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5. Exists as two slow interchanging conformational states, a structured (S) and disordered (D) form. May modulate NFS1 desulfurase activity in a zinc-dependent manner. Modulates the interaction between FXN and the cysteine desulfurase complex.

419612:USP16
gene id: 419612:USP16
uniprot id: A0A8B6Y8J8
uniprot id: A0A8B6YAZ5
uniprot id: A0A8B7K3H1
uniprot id: A0A8B8SQH0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. USP16 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homotetramer.
messages: Nucleus
messages: Phosphorylated at the onset of mitosis and dephosphorylated during the metaphase/anaphase transition. Phosphorylation by AURKB enhances the deubiquitinase activity.
messages: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
messages: The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin.

419612:SUMF1
gene id: 419612:SUMF1
uniprot id: A0A8B8R7G9
uniprot id: A0A8B8R7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

419612:UBR3
gene id: 419612:UBR3
uniprot id: A0A8B8T0A8
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

419612:PHKB
gene id: 419612:PHKB
uniprot id: A0A8B8TIS8
uniprot id: A0A8B8TIT0
uniprot id: A0A8B8TIU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

419612:ZP3
gene id: 419612:ZP3
uniprot id: A0A8B6YC13
uniprot id: A0A8B8RBY8
uniprot id: A0A8B8RBZ2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

419612:LOC102506990
gene id: 419612:LOC102506990
uniprot id: A0A8B6YBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

419612:KYNU
gene id: 419612:KYNU
uniprot id: A0A8B6YLG8
uniprot id: A0A8B8SZ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
messages: Cytoplasm
messages: Homodimer.

419612:EPHA2
gene id: 419612:EPHA2
uniprot id: A0A8B8U985
names: Subcellular Location Annotation
messages: Membrane

419612:DOP1B
gene id: 419612:DOP1B
uniprot id: A0A8B8S692
names: Similarity
messages: Belongs to the dopey family.

419612:ITGAD
gene id: 419612:ITGAD
uniprot id: A0A8B7K8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

419612:SLC34A3
gene id: 419612:SLC34A3
uniprot id: A0A8B8SXW5
uniprot id: A0A8B8SXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

419612:LOC102505031
gene id: 419612:LOC102505031
uniprot id: A0A8B8SF90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

419612:IL1A
gene id: 419612:IL1A
uniprot id: A0A8B7KB83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Cytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important role in inflammation and bridges the innate and adaptive immune systems. After binding to its receptor IL1R1 together with its accessory protein IL1RAP, forms the high affinity interleukin-1 receptor complex. Signaling involves the recruitment of adapter molecules such as MYD88, IRAK1 or IRAK4. In turn, mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways. Within the cell, acts as an alarmin and cell death results in its liberation in the extracellular space after disruption of the cell membrane to induce inflammation and alert the host to injury or damage. In addition to its role as a danger signal, which occurs when the cytokine is passively released by cell necrosis, directly senses DNA damage and acts as signal for genotoxic stress without loss of cell integrity.
messages: Cytoplasm
messages: Monomer. Interacts with TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion. Interacts with IL1R1. Interacts with S100A13; this interaction is the first step in the export of IL1A, followed by direct translocation of this complex across the plasma membrane.
messages: Nucleus
messages: Secreted

419612:LOC102504552
gene id: 419612:LOC102504552
uniprot id: A0A8B8SYI2
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:LOC102517739
gene id: 419612:LOC102517739
uniprot id: A0A8B8UAF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.

419612:PYCR3
gene id: 419612:PYCR3
uniprot id: A0A8B8S058
uniprot id: A0A8B8S1H3
uniprot id: A0A8B8S1S7
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

419612:SPTSSA
gene id: 419612:SPTSSA
uniprot id: A0A8B8T6G3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:RTN2
gene id: 419612:RTN2
uniprot id: A0A8B7K8Q3
uniprot id: A0A8B8THK6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:GOLGA5
gene id: 419612:GOLGA5
uniprot id: A0A8B6YIX1
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

419612:HAMP
gene id: 419612:HAMP
uniprot id: A0A8B8TP71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

419612:CLRN1
gene id: 419612:CLRN1
uniprot id: A0A8B6YKQ7
uniprot id: A0A8B6YN82
uniprot id: A0A8B8TJ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

419612:LDLRAD4
gene id: 419612:LDLRAD4
uniprot id: A0A8B8RYF8
uniprot id: A0A8B8RYG3
uniprot id: A0A8B8RYG8
uniprot id: A0A8B8RZU5
uniprot id: A0A8B8RZW9
uniprot id: A0A8B8S047
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:ERI1
gene id: 419612:ERI1
uniprot id: A0A8B6YCU9
names: Subcellular Location Annotation
messages: Cytoplasm

419612:OSBPL2
gene id: 419612:OSBPL2
uniprot id: A0A8B8RHH6
uniprot id: A0A8B8RHH9
uniprot id: A0A8B8RHQ3
uniprot id: A0A8B8RJU7
names: Similarity
messages: Belongs to the OSBP family.

419612:LMOD1
gene id: 419612:LMOD1
uniprot id: A0A8B8RXX3
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

419612:FOXA3
gene id: 419612:FOXA3
uniprot id: A0A8B6YB12
names: Subcellular Location Annotation
messages: Nucleus

419612:DIAPH3
gene id: 419612:DIAPH3
uniprot id: A0A8B8UDX9
uniprot id: A0A8B8UEN8
uniprot id: A0A8B8UEQ8
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

419612:NPY2R
gene id: 419612:NPY2R
uniprot id: S9WJX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:ZKSCAN2
gene id: 419612:ZKSCAN2
uniprot id: A0A8B6YII0
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

419612:LOC102515505
gene id: 419612:LOC102515505
uniprot id: S9WB58
names: Similarity
messages: Belongs to the peptidase A1 family.

419612:LOC102512904
gene id: 419612:LOC102512904
uniprot id: A0A8B8RJA7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

419612:LOC102514512
gene id: 419612:LOC102514512
uniprot id: A0A8B6YM35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SLC30A3
gene id: 419612:SLC30A3
uniprot id: A0A8B8UEV4
uniprot id: A0A8B8UEW5
uniprot id: A0A8B8UFN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

419612:ATP1B3
gene id: 419612:ATP1B3
uniprot id: A0A8B8TLM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

419612:PITX1
gene id: 419612:PITX1
uniprot id: A0A8B8SRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

419612:PARVB
gene id: 419612:PARVB
uniprot id: A0A8B8U138
uniprot id: A0A8B8U141
uniprot id: A0A8B8U1H4
uniprot id: A0A8B8U242
uniprot id: A0A8B8U2D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane

419612:GTF2H4
gene id: 419612:GTF2H4
uniprot id: A0A8B6YAE8
uniprot id: A0A8B8RPT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

419612:SERPIND1
gene id: 419612:SERPIND1
uniprot id: S9YGW7
names: Similarity
messages: Belongs to the serpin family.

419612:ZDHHC16
gene id: 419612:ZDHHC16
uniprot id: A0A8B6YG27
uniprot id: A0A8B6YJR9
uniprot id: A0A8B7KAI2
uniprot id: A0A8B8TXL9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

419612:SPIN4
gene id: 419612:SPIN4
uniprot id: S9WCJ9
names: Similarity
messages: Belongs to the SPIN/STSY family.

419612:TTC30B
gene id: 419612:TTC30B
uniprot id: A0A8B8T119
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

419612:MOGAT1
gene id: 419612:MOGAT1
uniprot id: A0A8B6YHI3
uniprot id: A0A8B8T2N6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:EGFL6
gene id: 419612:EGFL6
uniprot id: A0A8B6YPC3
uniprot id: A0A8B8SNA1
uniprot id: A0A8B8SQF8
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:TPRG1L
gene id: 419612:TPRG1L
uniprot id: A0A8B8U9G9
names: Similarity
messages: Belongs to the TPRG1 family.

419612:LOC116667805
gene id: 419612:LOC116667805
uniprot id: A0A8B8U6C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102524239
gene id: 419612:LOC102524239
uniprot id: A0A8B6Y9U6
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:TNNT3
gene id: 419612:TNNT3
uniprot id: A0A8B8TUU1
uniprot id: A0A8B8TUU3
uniprot id: A0A8B8TUU6
uniprot id: A0A8B8TUU8
uniprot id: A0A8B8TUU9
uniprot id: A0A8B8TUV2
uniprot id: A0A8B8TUV4
uniprot id: A0A8B8TUV6
uniprot id: A0A8B8TUV7
uniprot id: A0A8B8TUV9
uniprot id: A0A8B8TUW1
uniprot id: A0A8B8TUW2
uniprot id: A0A8B8TUW4
uniprot id: A0A8B8TUW6
uniprot id: A0A8B8TUW7
uniprot id: A0A8B8TUX1
uniprot id: A0A8B8TUX2
uniprot id: A0A8B8TUX4
uniprot id: A0A8B8TUX6
uniprot id: A0A8B8TUX7
uniprot id: A0A8B8TUX8
uniprot id: A0A8B8TUY0
uniprot id: A0A8B8TUY1
uniprot id: A0A8B8TUY3
uniprot id: A0A8B8TUY4
uniprot id: A0A8B8TUY5
uniprot id: A0A8B8TUY8
uniprot id: A0A8B8TVX2
uniprot id: A0A8B8TVX5
uniprot id: A0A8B8TVY4
uniprot id: A0A8B8TVY9
uniprot id: A0A8B8TVZ2
uniprot id: A0A8B8TVZ6
uniprot id: A0A8B8TW00
uniprot id: A0A8B8TW05
uniprot id: A0A8B8TW10
uniprot id: A0A8B8TW34
uniprot id: A0A8B8TW39
uniprot id: A0A8B8TW44
uniprot id: A0A8B8TW49
uniprot id: A0A8B8TW54
uniprot id: A0A8B8TW59
uniprot id: A0A8B8TW64
uniprot id: A0A8B8TW75
uniprot id: A0A8B8TW80
names: Caution
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

419612:GPR65
gene id: 419612:GPR65
uniprot id: A0A8B8T7Y7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:TRMT1L
gene id: 419612:TRMT1L
uniprot id: A0A8B6YK51
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

419612:CNNM1
gene id: 419612:CNNM1
uniprot id: A0A8B6YGJ6
uniprot id: A0A8B7K9U0
uniprot id: A0A8B8TXI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

419612:FRZB
gene id: 419612:FRZB
uniprot id: A0A8B8T0H9
names: Caution
names: Function
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

419612:CHUK
gene id: 419612:CHUK
uniprot id: A0A8B8TXF9
uniprot id: A0A8B8TYI4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

419612:TOM1L1
gene id: 419612:TOM1L1
uniprot id: A0A8B8UIH0
uniprot id: A0A8B8UIY7
uniprot id: A0A8B8UJ00
names: Similarity
messages: Belongs to the TOM1 family.

419612:MAPRE1
gene id: 419612:MAPRE1
uniprot id: A0A8B8RL09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

419612:ANXA5
gene id: 419612:ANXA5
uniprot id: A0A8B8RL77
names: Domain
names: Function
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

419612:LOC102520459
gene id: 419612:LOC102520459
uniprot id: A0A8B8SVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

419612:ERCC2
gene id: 419612:ERCC2
uniprot id: A0A8B8THI5
uniprot id: A0A8B8THJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

419612:GC
gene id: 419612:GC
uniprot id: A0A8B7KEP4
names: Function
names: Subcellular Location Annotation
messages: Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
messages: Secreted

419612:ATXN3
gene id: 419612:ATXN3
uniprot id: A0A8B8T856
uniprot id: A0A8B8T857
uniprot id: A0A8B8T8B0
names: Subcellular Location Annotation
messages: Nucleus

419612:SNX31
gene id: 419612:SNX31
uniprot id: A0A8B6YMR3
uniprot id: A0A8B8S0C7
uniprot id: A0A8B8S0E1
uniprot id: A0A8B8S1Q1
uniprot id: A0A8B8S1Y7
names: Similarity
messages: Belongs to the sorting nexin family.

419612:LOC102512042
gene id: 419612:LOC102512042
uniprot id: A0A8B6YT56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RBP2
gene id: 419612:RBP2
uniprot id: A0A8B6YKL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

419612:ENSA
gene id: 419612:ENSA
uniprot id: A0A8B6YIF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

419612:GIPC2
gene id: 419612:GIPC2
uniprot id: A0A8B6YIV0
uniprot id: A0A8B8U7H7
names: Similarity
messages: Belongs to the GIPC family.

419612:MAPKAPK2
gene id: 419612:MAPKAPK2
uniprot id: A0A8B8RZS5
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:LOC102505502
gene id: 419612:LOC102505502
uniprot id: A0A8B8TWR8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TRPV5
gene id: 419612:TRPV5
uniprot id: A0A8B8TB10
uniprot id: A0A8B8TB14
uniprot id: A0A8B8TB17
uniprot id: A0A8B8TB49
uniprot id: A0A8B8TBE1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:KIF18A
gene id: 419612:KIF18A
uniprot id: A0A8B8TPT4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:GPHN
gene id: 419612:GPHN
uniprot id: A0A8B8T766
uniprot id: A0A8B8T770
uniprot id: A0A8B8T771
uniprot id: A0A8B8T775
uniprot id: A0A8B8T7E8
uniprot id: A0A8B8T7F3
uniprot id: A0A8B8T7S6
uniprot id: A0A8B8T835
uniprot id: A0A8B8T839
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

419612:LOC102516338
gene id: 419612:LOC102516338
uniprot id: A0A8B8SQ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm

419612:KCNV2
gene id: 419612:KCNV2
uniprot id: A0A8B6YES5
names: Subcellular Location Annotation
messages: Membrane

419612:STAT5B
gene id: 419612:STAT5B
uniprot id: A0A8B8R541
uniprot id: A0A8B8R5B1
uniprot id: A0A8B8R7T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

419612:SPDYA
gene id: 419612:SPDYA
uniprot id: A0A8B8UF05
names: Similarity
messages: Belongs to the Speedy/Ringo family.

419612:SERPINB5
gene id: 419612:SERPINB5
uniprot id: A0A8B6YDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family. Ov-serpin subfamily.
messages: extracellular space

419612:HCN3
gene id: 419612:HCN3
uniprot id: A0A8B6Y8S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

419612:GSTP1
gene id: 419612:GSTP1
uniprot id: A0A8B7K4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

419612:LOC102522750
gene id: 419612:LOC102522750
uniprot id: A0A8B8U7N9
uniprot id: A0A8B8U7S0
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:HAO1
gene id: 419612:HAO1
uniprot id: A0A8B6YLK3
uniprot id: A0A8B7KBI9
uniprot id: A0A8B8RIG1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

419612:CD68
gene id: 419612:CD68
uniprot id: A0A8B6Y813
uniprot id: A0A8B8UJL3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

419612:PLCB3
gene id: 419612:PLCB3
uniprot id: A0A8B8TTG8
uniprot id: A0A8B8TTG9
uniprot id: A0A8B8TTI0
uniprot id: A0A8B8TUK2
uniprot id: A0A8B8TUK6
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

419612:LOC102506031
gene id: 419612:LOC102506031
uniprot id: A0A8B7K8E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:DHRS11
gene id: 419612:DHRS11
uniprot id: A0A8B6Y5D9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:PGPEP1L
gene id: 419612:PGPEP1L
uniprot id: A0A8B8S3H4
names: Similarity
messages: Belongs to the peptidase C15 family.

419612:TMTC2
gene id: 419612:TMTC2
uniprot id: A0A8B6YNC4
uniprot id: A0A8B8U543
uniprot id: A0A8B8U5Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

419612:LOC102524608
gene id: 419612:LOC102524608
uniprot id: S9WX78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:NKX2-6
gene id: 419612:NKX2-6
uniprot id: A0A8B8SB52
names: Subcellular Location Annotation
messages: Nucleus

419612:SGCG
gene id: 419612:SGCG
uniprot id: A0A8B8UCN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

419612:TEKT4
gene id: 419612:TEKT4
uniprot id: S9XPS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

419612:STS
gene id: 419612:STS
uniprot id: A0A8B6YPN7
uniprot id: A0A8B8SLV0
uniprot id: A0A8B8SP16
names: Similarity
messages: Belongs to the sulfatase family.

419612:LOC102518240
gene id: 419612:LOC102518240
uniprot id: A0A8B8RGM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:KCNJ13
gene id: 419612:KCNJ13
uniprot id: A0A8B6YL72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

419612:LOC106730951
gene id: 419612:LOC106730951
uniprot id: S9XPG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:NPTX1
gene id: 419612:NPTX1
uniprot id: A0A8B8R3J5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:RER1
gene id: 419612:RER1
uniprot id: A0A8B7KCM1
uniprot id: A0A8B8U992
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

419612:LOC102523216
gene id: 419612:LOC102523216
uniprot id: A0A8B8SIK3
names: Similarity
messages: Belongs to the intermediate filament family.

419612:LOC106730598
gene id: 419612:LOC106730598
uniprot id: A0A8B7KEV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FANCM
gene id: 419612:FANCM
uniprot id: A0A8B6YE28
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.

419612:UBN1
gene id: 419612:UBN1
uniprot id: A0A8B7K405
names: Similarity
messages: Belongs to the ubinuclein family.

419612:ORC6
gene id: 419612:ORC6
uniprot id: A0A8B6YLK2
uniprot id: A0A8B7KEI4
uniprot id: A0A8B8TIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

419612:PTGS1
gene id: 419612:PTGS1
uniprot id: A0A8B8SWP9
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:PPFIBP2
gene id: 419612:PPFIBP2
uniprot id: A0A8B8TRV4
uniprot id: A0A8B8TRV7
uniprot id: A0A8B8TRV8
uniprot id: A0A8B8TRW3
uniprot id: A0A8B8TRW4
uniprot id: A0A8B8TRW5
uniprot id: A0A8B8TRW8
uniprot id: A0A8B8TRX3
uniprot id: A0A8B8TRX4
uniprot id: A0A8B8TRX5
uniprot id: A0A8B8TSR0
uniprot id: A0A8B8TSS0
uniprot id: A0A8B8TST0
uniprot id: A0A8B8TSY9
uniprot id: A0A8B8TSZ6
uniprot id: A0A8B8TT01
uniprot id: A0A8B8TT05
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

419612:TPX2
gene id: 419612:TPX2
uniprot id: A0A8B8RJ32
uniprot id: A0A8B8RJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

419612:LOC102514790
gene id: 419612:LOC102514790
uniprot id: A0A8B8R789
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

419612:LOC102506051
gene id: 419612:LOC102506051
uniprot id: A0A8B6YJ48
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

419612:SNF8
gene id: 419612:SNF8
uniprot id: S9YT70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

419612:C25H8orf37
gene id: 419612:C25H8orf37
uniprot id: A0A8B8S1X3
uniprot id: A0A8B8S1X4
uniprot id: A0A8B8S1X9
uniprot id: A0A8B8S389
uniprot id: A0A8B8S3I4
uniprot id: A0A8B8S3I9
uniprot id: A0A8B8S3N0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

419612:GALR2
gene id: 419612:GALR2
uniprot id: A0A8B6YPW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

419612:PGM2
gene id: 419612:PGM2
uniprot id: A0A8B8UAG4
uniprot id: A0A8B8UBT5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

419612:KLC4
gene id: 419612:KLC4
uniprot id: A0A8B6YM64
uniprot id: A0A8B8RM42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

419612:COG3
gene id: 419612:COG3
uniprot id: A0A8B8UCK2
names: Function
names: Similarity
messages: Belongs to the COG3 family.
messages: Involved in ER-Golgi transport.

419612:NUMBL
gene id: 419612:NUMBL
uniprot id: A0A8B8TI35
uniprot id: A0A8B8TI45
uniprot id: A0A8B8TI49
uniprot id: A0A8B8TI52
uniprot id: A0A8B8TI61
uniprot id: A0A8B8TJC4
uniprot id: A0A8B8TJC9
names: Function
messages: Plays a role in the process of neurogenesis.

419612:DMTN
gene id: 419612:DMTN
uniprot id: A0A8B8SAQ4
uniprot id: A0A8B8SAQ9
uniprot id: A0A8B8SAV9
uniprot id: A0A8B8SAW2
names: Subcellular Location Annotation
messages: Cytoplasm

419612:SERPINB2
gene id: 419612:SERPINB2
uniprot id: A0A8B6YR19
names: Similarity
messages: Belongs to the serpin family.

419612:ZIC2
gene id: 419612:ZIC2
uniprot id: A0A8B8UDF8
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

419612:GRB2
gene id: 419612:GRB2
uniprot id: T0M477
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

419612:ENPEP
gene id: 419612:ENPEP
uniprot id: A0A8B6YLA9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

419612:SNAPC3
gene id: 419612:SNAPC3
uniprot id: A0A8B6YIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

419612:LOC102522638
gene id: 419612:LOC102522638
uniprot id: S9X878
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CHST3
gene id: 419612:CHST3
uniprot id: A0A8B8S9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

419612:LOC102503764
gene id: 419612:LOC102503764
uniprot id: A0A8B7KBJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
messages: Membrane

419612:CAV2
gene id: 419612:CAV2
uniprot id: A0A8B6Y9C1
uniprot id: A0A8B7K5D9
uniprot id: A0A8B8TBP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

419612:UBE2R2
gene id: 419612:UBE2R2
uniprot id: A0A8B8STR3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:EDNRA
gene id: 419612:EDNRA
uniprot id: A0A8B8RTA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

419612:STK17B
gene id: 419612:STK17B
uniprot id: A0A8B8T190
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:CILP
gene id: 419612:CILP
uniprot id: A0A8B6YEQ2
uniprot id: A0A8B7K9Q6
names: Subcellular Location Annotation
messages: extracellular matrix

419612:LOC102523901
gene id: 419612:LOC102523901
uniprot id: A0A8B7KI68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RPS12
gene id: 419612:RPS12
uniprot id: T0MHV6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

419612:NRP1
gene id: 419612:NRP1
uniprot id: A0A8B8SHK4
uniprot id: A0A8B8SHK5
uniprot id: A0A8B8SIN3
uniprot id: A0A8B8SIU2
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC116656648
gene id: 419612:LOC116656648
uniprot id: S9X3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

419612:DZIP1
gene id: 419612:DZIP1
uniprot id: A0A8B8UDJ6
uniprot id: A0A8B8UDJ9
uniprot id: A0A8B8UEA6
uniprot id: A0A8B8UEB7
uniprot id: A0A8B8UEX3
uniprot id: A0A8B8UEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: cilium basal body

419612:RFLNB
gene id: 419612:RFLNB
uniprot id: A0A8B8R642
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

419612:TMEM121B
gene id: 419612:TMEM121B
uniprot id: A0A8B8SFF9
uniprot id: A0A8B8SI27
names: Similarity
messages: Belongs to the TMEM121 family.

419612:POSTN
gene id: 419612:POSTN
uniprot id: A0A8B6YDH7
uniprot id: A0A8B6YDH8
uniprot id: A0A8B6YDI3
uniprot id: A0A8B6YDV9
uniprot id: A0A8B6YES7
uniprot id: A0A8B6YHM1
uniprot id: A0A8B7KAN7
names: Subcellular Location Annotation
messages: extracellular matrix

419612:ERBB3
gene id: 419612:ERBB3
uniprot id: A0A8B6YB22
uniprot id: A0A8B7K732
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

419612:TBX3
gene id: 419612:TBX3
uniprot id: A0A8B8SCW0
uniprot id: A0A8B8SE08
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

419612:ERCC1
gene id: 419612:ERCC1
uniprot id: A0A8B8THL1
uniprot id: A0A8B8TIS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

419612:KEG61 p05
gene id: 419612:KEG61_p05
uniprot id: A6YAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

419612:ACTL7A
gene id: 419612:ACTL7A
uniprot id: A0A8B6YC95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: cytoskeleton

419612:PLPP4
gene id: 419612:PLPP4
uniprot id: A0A8B8TWI8
uniprot id: A0A8B8TXW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

419612:NIF3L1
gene id: 419612:NIF3L1
uniprot id: A0A8B8T1I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

419612:CAB39L
gene id: 419612:CAB39L
uniprot id: A0A8B7KA40
uniprot id: A0A8B8UD77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

419612:DNAH14
gene id: 419612:DNAH14
uniprot id: A0A8B8RYH7
names: Similarity
messages: Belongs to the dynein heavy chain family.

419612:TRHR
gene id: 419612:TRHR
uniprot id: S9Y4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

419612:AP2A2
gene id: 419612:AP2A2
uniprot id: A0A8B8TV29
uniprot id: A0A8B8TV30
uniprot id: A0A8B8TV31
uniprot id: A0A8B8TV35
uniprot id: A0A8B8TW55
uniprot id: A0A8B8TW60
uniprot id: A0A8B8TWC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

419612:LOC102520290
gene id: 419612:LOC102520290
uniprot id: S9WSM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:CTNNA2
gene id: 419612:CTNNA2
uniprot id: A0A8B7KBL8
uniprot id: A0A8B7KCK5
uniprot id: A0A8B8SIK0
uniprot id: A0A8B8SIK4
uniprot id: A0A8B8SL06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

419612:TBX4
gene id: 419612:TBX4
uniprot id: A0A8B8UI68
uniprot id: A0A8B8UIA7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

419612:TPMT
gene id: 419612:TPMT
uniprot id: A0A8B8RKI4
uniprot id: A0A8B8RKJ0
uniprot id: A0A8B8RKJ1
uniprot id: A0A8B8RMA6
uniprot id: A0A8B8RMR5
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Monomer.

419612:CTSD
gene id: 419612:CTSD
uniprot id: A0A8B8TUZ7
uniprot id: A0A8B8TW15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome
messages: extracellular space

419612:COL4A4
gene id: 419612:COL4A4
uniprot id: A0A8B8T2A3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

419612:ATL1
gene id: 419612:ATL1
uniprot id: A0A8B7KFF0
uniprot id: A0A8B8T790
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

419612:SLC25A19
gene id: 419612:SLC25A19
uniprot id: T0MFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:LOC116659023
gene id: 419612:LOC116659023
uniprot id: A0A8B8RUH9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MCM3
gene id: 419612:MCM3
uniprot id: A0A8B8RMI6
uniprot id: A0A8B8RMU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

419612:TMPRSS11E
gene id: 419612:TMPRSS11E
uniprot id: A0A8B8RAB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

419612:VWA2
gene id: 419612:VWA2
uniprot id: A0A8B8TWR0
uniprot id: A0A8B8TXS1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:HOXA4
gene id: 419612:HOXA4
uniprot id: A0A8B8TBT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

419612:LOC102519216
gene id: 419612:LOC102519216
uniprot id: A0A8B8RPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MSH2
gene id: 419612:MSH2
uniprot id: A0A8B8UFL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

419612:HNRNPK
gene id: 419612:HNRNPK
uniprot id: A0A8B8STF8
uniprot id: A0A8B8STJ7
uniprot id: A0A8B8STY4
uniprot id: A0A8B8SUD6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm
messages: podosome

419612:CCNE2
gene id: 419612:CCNE2
uniprot id: A0A8B8S0R6
uniprot id: A0A8B8S2D4
names: Similarity
messages: Belongs to the cyclin family.

419612:TSEN15
gene id: 419612:TSEN15
uniprot id: A0A8B8RQG5
names: Similarity
messages: Belongs to the SEN15 family.

419612:LOC102523993
gene id: 419612:LOC102523993
uniprot id: A0A8B6YA27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

419612:TM4SF4
gene id: 419612:TM4SF4
uniprot id: A0A8B6YLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

419612:SLC12A2
gene id: 419612:SLC12A2
uniprot id: A0A8B8SQV0
uniprot id: A0A8B8SSS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

419612:LOC102520273
gene id: 419612:LOC102520273
uniprot id: A0A8B8TVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:STX19
gene id: 419612:STX19
uniprot id: A0A8B7KE45
names: Similarity
messages: Belongs to the syntaxin family.

419612:LOC102506544
gene id: 419612:LOC102506544
uniprot id: A0A8B8S3Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

419612:VPS53
gene id: 419612:VPS53
uniprot id: A0A8B6YJN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

419612:LOC102520044
gene id: 419612:LOC102520044
uniprot id: T0NSK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:RAX2
gene id: 419612:RAX2
uniprot id: A0A8B8RV38
names: Subcellular Location Annotation
messages: Nucleus

419612:STRADB
gene id: 419612:STRADB
uniprot id: A0A8B8T121
uniprot id: A0A8B8T123
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

419612:LOC102517276
gene id: 419612:LOC102517276
uniprot id: A0A8B6YBJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

419612:PRDM13
gene id: 419612:PRDM13
uniprot id: A0A8B8TGF5
names: Subcellular Location Annotation
messages: Nucleus

419612:TIMELESS
gene id: 419612:TIMELESS
uniprot id: A0A8B8U2Z7
uniprot id: A0A8B8U478
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

419612:PIP4P1
gene id: 419612:PIP4P1
uniprot id: A0A8B8T5R6
uniprot id: A0A8B8T6B7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

419612:ZNF446
gene id: 419612:ZNF446
uniprot id: A0A8B8TM80
uniprot id: A0A8B8TM90
uniprot id: A0A8B8TMM7
uniprot id: A0A8B8TNF2
names: Subcellular Location Annotation
messages: Nucleus

419612:CRCP
gene id: 419612:CRCP
uniprot id: A0A8B7K8A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

419612:CDC73
gene id: 419612:CDC73
uniprot id: A0A8B8RXK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

419612:LOC116663185
gene id: 419612:LOC116663185
uniprot id: A0A8B8SUY4
uniprot id: A0A8B8SVI3
uniprot id: A0A8B8SW81
names: Subcellular Location Annotation
messages: Membrane

419612:TPO
gene id: 419612:TPO
uniprot id: A0A8B8UES7
uniprot id: A0A8B8UEU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Interacts with DUOX1, DUOX2 and CYBA.
messages: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:TUSC3
gene id: 419612:TUSC3
uniprot id: A0A8B8S2Y0
uniprot id: A0A8B8S499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:PRKD1
gene id: 419612:PRKD1
uniprot id: A0A8B8T623
uniprot id: A0A8B8T6P2
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

419612:LOC102513344
gene id: 419612:LOC102513344
uniprot id: A0A8B6YF74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SLC17A7
gene id: 419612:SLC17A7
uniprot id: A0A8B8TI29
names: Subcellular Location Annotation
messages: Membrane

419612:TMEM150C
gene id: 419612:TMEM150C
uniprot id: A0A8B6YKM5
uniprot id: A0A8B8R3L3
uniprot id: A0A8B8R5W2
names: Subcellular Location Annotation
messages: Membrane

419612:MPPED1
gene id: 419612:MPPED1
uniprot id: A0A8B8U229
names: Similarity
messages: Belongs to the UPF0046 family.

419612:MCM5
gene id: 419612:MCM5
uniprot id: A0A8B7K9Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

419612:FAM193B
gene id: 419612:FAM193B
uniprot id: A0A8B7K3X2
uniprot id: A0A8B8RSB1
uniprot id: A0A8B8RSC1
uniprot id: A0A8B8RSC3
uniprot id: A0A8B8RSC8
uniprot id: A0A8B8RT59
uniprot id: A0A8B8RT69
uniprot id: A0A8B8RTY6
uniprot id: A0A8B8RTZ1
uniprot id: A0A8B8RU98
uniprot id: A0A8B8RUA9
names: Similarity
messages: Belongs to the FAM193 family.

419612:FOXJ3
gene id: 419612:FOXJ3
uniprot id: A0A8B6Y734
uniprot id: A0A8B8U5J9
uniprot id: A0A8B8U5K1
uniprot id: A0A8B8U6G6
names: Subcellular Location Annotation
messages: Nucleus

419612:PIWIL4
gene id: 419612:PIWIL4
uniprot id: A0A8B8TQR5
names: Similarity
messages: Belongs to the argonaute family.

419612:CCDC167
gene id: 419612:CCDC167
uniprot id: A0A8B8RLR3
names: Subcellular Location Annotation
messages: Membrane

419612:GMPPB
gene id: 419612:GMPPB
uniprot id: A0A8B8RAX6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

419612:LOC106728765
gene id: 419612:LOC106728765
uniprot id: A0A8B8RUM5
uniprot id: A0A8B8RUM9
names: Similarity
messages: Belongs to the adenylate kinase family.

419612:PTEN
gene id: 419612:PTEN
uniprot id: A0A8B6YJ91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

419612:MEF2C
gene id: 419612:MEF2C
uniprot id: A0A8B6YJM9
uniprot id: A0A8B8SNE6
uniprot id: A0A8B8SPE2
uniprot id: A0A8B8SPQ0
uniprot id: A0A8B8SQF0
names: Subcellular Location Annotation
messages: Nucleus

419612:CAPN5
gene id: 419612:CAPN5
uniprot id: A0A8B8TTX6
names: Similarity
messages: Belongs to the peptidase C2 family.

419612:EIF1B
gene id: 419612:EIF1B
uniprot id: A0A8B8RAS2
names: Similarity
messages: Belongs to the SUI1 family.

419612:CLDN3
gene id: 419612:CLDN3
uniprot id: S9YIN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

419612:TYRO3
gene id: 419612:TYRO3
uniprot id: A0A8B8T516
uniprot id: A0A8B8T545
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

419612:TBX22
gene id: 419612:TBX22
uniprot id: A0A8B6YN23
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

419612:DPH5
gene id: 419612:DPH5
uniprot id: A0A8B8TLH9
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

419612:PPP1R12A
gene id: 419612:PPP1R12A
uniprot id: A0A8B6YEA0
uniprot id: A0A8B7K663
uniprot id: A0A8B7K695
uniprot id: A0A8B8U4T2
uniprot id: A0A8B8U4T6
uniprot id: A0A8B8U5Y4
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

419612:LOC102517712
gene id: 419612:LOC102517712
uniprot id: A0A8B7KAY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:P2RX2
gene id: 419612:P2RX2
uniprot id: A0A8B8SC86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

419612:PARPBP
gene id: 419612:PARPBP
uniprot id: A0A8B6YGX4
uniprot id: A0A8B8U555
uniprot id: A0A8B8U5D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

419612:TAGLN
gene id: 419612:TAGLN
uniprot id: S9XCL8
names: Similarity
messages: Belongs to the calponin family.

419612:TJP2
gene id: 419612:TJP2
uniprot id: A0A8B8SU92
uniprot id: A0A8B8SU97
uniprot id: A0A8B8SUG8
uniprot id: A0A8B8SUH3
uniprot id: A0A8B8SUP4
uniprot id: A0A8B8SV43
uniprot id: A0A8B8SVT2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

419612:LIN7A
gene id: 419612:LIN7A
uniprot id: A0A8B8U628
names: Subcellular Location Annotation
messages: Cell membrane

419612:SPRN
gene id: 419612:SPRN
uniprot id: A0A8B8TXB5
names: Function
names: Similarity
messages: Belongs to the SPRN family.
messages: Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.

419612:DEFB126
gene id: 419612:DEFB126
uniprot id: A0A8B8RIY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

419612:LOC102518571
gene id: 419612:LOC102518571
uniprot id: A0A8B6YD37
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

419612:CELSR3
gene id: 419612:CELSR3
uniprot id: A0A8B8RB33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

419612:MPP5
gene id: 419612:MPP5
uniprot id: A0A8B8T7F7
uniprot id: A0A8B8T844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Endomembrane system
messages: adherens junction
messages: tight junction

419612:AXIN1
gene id: 419612:AXIN1
uniprot id: A0A8B8RF49
uniprot id: A0A8B8RHL5
names: Subcellular Location Annotation
messages: Cytoplasm

419612:SAP30L
gene id: 419612:SAP30L
uniprot id: A0A8B8SSG8
names: Similarity
messages: Belongs to the SAP30 family.

419612:PMEPA1
gene id: 419612:PMEPA1
uniprot id: A0A8B6YHZ0
uniprot id: A0A8B8RH87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

419612:LOC102524538
gene id: 419612:LOC102524538
uniprot id: A0A8B7KAQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

419612:LOC102516682
gene id: 419612:LOC102516682
uniprot id: A0A8B8RWT2
uniprot id: A0A8B8RX29
names: Subcellular Location Annotation
messages: Membrane

419612:LETM2
gene id: 419612:LETM2
uniprot id: A0A8B8S4H6
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

419612:LOC102512612
gene id: 419612:LOC102512612
uniprot id: A0A8B8RIJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:CCDC172
gene id: 419612:CCDC172
uniprot id: A0A8B8TWN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC172 family.
messages: Cytoplasm

419612:MAS1
gene id: 419612:MAS1
uniprot id: A0A8B8THE4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:RDH12
gene id: 419612:RDH12
uniprot id: A0A8B6YHB6
uniprot id: A0A8B8T7H0
uniprot id: A0A8B8T859
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:PFN1
gene id: 419612:PFN1
uniprot id: A0A8B8UIS4
names: Similarity
messages: Belongs to the profilin family.

419612:ZFPM2
gene id: 419612:ZFPM2
uniprot id: A0A8B8S1A7
uniprot id: A0A8B8S2N2
names: Subcellular Location Annotation
messages: Nucleus

419612:HNRNPA2B1
gene id: 419612:HNRNPA2B1
uniprot id: A0A8B6Y7Z2
uniprot id: A0A8B6YB97
uniprot id: A0A8B7K3S0
uniprot id: A0A8B8TBU9
uniprot id: A0A8B8TBZ1
uniprot id: A0A8B8TD24
names: Subcellular Location Annotation
messages: Cytoplasmic granule

419612:KIFC1
gene id: 419612:KIFC1
uniprot id: A0A8B6YBN3
uniprot id: A0A8B7K729
uniprot id: A0A8B7K9A8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:LOC116662272
gene id: 419612:LOC116662272
uniprot id: A0A8B8SRF2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:GDPD2
gene id: 419612:GDPD2
uniprot id: A0A8B6YMD5
uniprot id: A0A8B8SKZ6
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

419612:OVOL2
gene id: 419612:OVOL2
uniprot id: A0A8B8RI82
uniprot id: A0A8B8RIE8
names: Subcellular Location Annotation
messages: Nucleus

419612:MARCHF11
gene id: 419612:MARCHF11
uniprot id: A0A8B8S8S8
names: Subcellular Location Annotation
messages: Membrane

419612:NME5
gene id: 419612:NME5
uniprot id: A0A8B6YFF5
uniprot id: A0A8B8SRE1
names: Similarity
messages: Belongs to the NDK family.

419612:RPS8
gene id: 419612:RPS8
uniprot id: A0A8B6Y9W0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

419612:ROR2
gene id: 419612:ROR2
uniprot id: A0A8B8S9M0
uniprot id: A0A8B8SAU1
uniprot id: A0A8B8SAZ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:NRXN1
gene id: 419612:NRXN1
uniprot id: A0A8B8UFL4
uniprot id: A0A8B8UFL9
uniprot id: A0A8B8UFM4
uniprot id: A0A8B8UFM9
uniprot id: A0A8B8UFN5
uniprot id: A0A8B8UFP4
uniprot id: A0A8B8UFP6
uniprot id: A0A8B8UFP9
uniprot id: A0A8B8UFQ2
uniprot id: A0A8B8UFQ4
uniprot id: A0A8B8UFQ7
uniprot id: A0A8B8UFR0
uniprot id: A0A8B8UFR6
uniprot id: A0A8B8UFS0
uniprot id: A0A8B8UFS6
uniprot id: A0A8B8UGC3
uniprot id: A0A8B8UGC8
uniprot id: A0A8B8UGD2
uniprot id: A0A8B8UGD3
uniprot id: A0A8B8UGD7
uniprot id: A0A8B8UGD8
uniprot id: A0A8B8UGE2
uniprot id: A0A8B8UGE3
uniprot id: A0A8B8UGE7
uniprot id: A0A8B8UGE9
uniprot id: A0A8B8UGF2
uniprot id: A0A8B8UGF4
uniprot id: A0A8B8UGF7
uniprot id: A0A8B8UGG0
uniprot id: A0A8B8UGG2
uniprot id: A0A8B8UH13
uniprot id: A0A8B8UH16
uniprot id: A0A8B8UH22
uniprot id: A0A8B8UH31
uniprot id: A0A8B8UH36
uniprot id: A0A8B8UH41
uniprot id: A0A8B8UH46
uniprot id: A0A8B8UH53
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Presynaptic cell membrane

419612:SLC44A2
gene id: 419612:SLC44A2
uniprot id: A0A8B8RUA0
uniprot id: A0A8B8RUA2
uniprot id: A0A8B8RVD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

419612:DPM2
gene id: 419612:DPM2
uniprot id: A0A8B6YGU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

419612:FAM229A
gene id: 419612:FAM229A
uniprot id: A0A8B8UAT3
names: Similarity
messages: Belongs to the FAM229 family.

419612:ART5
gene id: 419612:ART5
uniprot id: A0A8B6YCL4
uniprot id: A0A8B7K889
uniprot id: A0A8B8TS84
uniprot id: A0A8B8TS94
uniprot id: A0A8B8TTB3
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

419612:MYO3A
gene id: 419612:MYO3A
uniprot id: A0A8B8SJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

419612:BMP10
gene id: 419612:BMP10
uniprot id: S9WGV4
names: Similarity
messages: Belongs to the TGF-beta family.

419612:LOC102503980
gene id: 419612:LOC102503980
uniprot id: A0A8B6YQG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:PTPA
gene id: 419612:PTPA
uniprot id: A0A8B8SWS8
uniprot id: A0A8B8SX51
uniprot id: A0A8B8SY15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

419612:RDH13
gene id: 419612:RDH13
uniprot id: A0A8B8TN97
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:TP53BP1
gene id: 419612:TP53BP1
uniprot id: A0A8B6YE18
uniprot id: A0A8B8T4N5
uniprot id: A0A8B8T4N8
uniprot id: A0A8B8T4P3
uniprot id: A0A8B8T500
uniprot id: A0A8B8T5I1
names: Subcellular Location Annotation
messages: Nucleus

419612:MMP3
gene id: 419612:MMP3
uniprot id: A0A8B6YKT2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

419612:GSC2
gene id: 419612:GSC2
uniprot id: A0A8B8SD25
names: Subcellular Location Annotation
messages: Nucleus

419612:DUXB
gene id: 419612:DUXB
uniprot id: A0A8B8TP94
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102518769
gene id: 419612:LOC102518769
uniprot id: A0A8B8SI07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

419612:LOC102511688
gene id: 419612:LOC102511688
uniprot id: A0A8B6YG74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ATP9B
gene id: 419612:ATP9B
uniprot id: A0A8B7K5N4
uniprot id: A0A8B7K5Z8
uniprot id: A0A8B8S8F4
uniprot id: A0A8B8S8F6
uniprot id: A0A8B8S8F9
uniprot id: A0A8B8S9P9
uniprot id: A0A8B8S9Q4
uniprot id: A0A8B8S9Q8
uniprot id: A0A8B8S9V1
uniprot id: A0A8B8S9V7
uniprot id: A0A8B8S9W1
uniprot id: A0A8B8SAN7
uniprot id: A0A8B8SAP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

419612:ICAM4
gene id: 419612:ICAM4
uniprot id: A0A8B6YBW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

419612:PRKCE
gene id: 419612:PRKCE
uniprot id: A0A8B8UFH0
uniprot id: A0A8B8UGV3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration.
messages: Cell membrane
messages: Cytoplasm
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: cytoskeleton
messages: perinuclear region

419612:FOXQ1
gene id: 419612:FOXQ1
uniprot id: A0A8B8RJZ4
names: Subcellular Location Annotation
messages: Nucleus

419612:SLC6A15
gene id: 419612:SLC6A15
uniprot id: A0A8B8U5X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

419612:LZTFL1
gene id: 419612:LZTFL1
uniprot id: A0A8B8RCF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

419612:MEIS3
gene id: 419612:MEIS3
uniprot id: A0A8B8TH43
uniprot id: A0A8B8TH48
uniprot id: A0A8B8TH66
uniprot id: A0A8B8TH85
uniprot id: A0A8B8TH91
uniprot id: A0A8B8TIF2
uniprot id: A0A8B8TIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

419612:FBXO34
gene id: 419612:FBXO34
uniprot id: A0A8B8T6U0
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

419612:CCDC153
gene id: 419612:CCDC153
uniprot id: A0A8B6Y8M7
names: Similarity
messages: Belongs to the UPF0610 family.

419612:TONSL
gene id: 419612:TONSL
uniprot id: A0A8B8S1P5
uniprot id: A0A8B8S1P7
uniprot id: A0A8B8S312
uniprot id: A0A8B8S3A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tonsoku family.
messages: Chromosome

419612:MYLK2
gene id: 419612:MYLK2
uniprot id: A0A8B7K6Q4
uniprot id: A0A8B8RKX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm
messages: May interact with centrin.

419612:TMSB4X
gene id: 419612:TMSB4X
uniprot id: A0A8B7KIM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

419612:RSAD2
gene id: 419612:RSAD2
uniprot id: A0A8B8UE50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RSAD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

419612:CD99L2
gene id: 419612:CD99L2
uniprot id: A0A8B8SQ86
names: Similarity
messages: Belongs to the CD99 family.

419612:HSPA12A
gene id: 419612:HSPA12A
uniprot id: A0A8B6YEA5
uniprot id: A0A8B7K929
uniprot id: A0A8B8TY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: Perikaryon
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

419612:CAPN14
gene id: 419612:CAPN14
uniprot id: A0A8B8UF29
uniprot id: A0A8B8UGH4
names: Similarity
messages: Belongs to the peptidase C2 family.

419612:LOC102521854
gene id: 419612:LOC102521854
uniprot id: A0A8B7KGU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ZIC5
gene id: 419612:ZIC5
uniprot id: A0A8B8UES5
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

419612:TMEM14A
gene id: 419612:TMEM14A
uniprot id: A0A8B6YHC1
names: Similarity
messages: Belongs to the TMEM14 family.

419612:ENTPD3
gene id: 419612:ENTPD3
uniprot id: A0A8B8RDE0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

419612:GATA2
gene id: 419612:GATA2
uniprot id: A0A8B8R9K6
uniprot id: A0A8B8R9Q0
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102515470
gene id: 419612:LOC102515470
uniprot id: A0A8B8SI17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

419612:LETM1
gene id: 419612:LETM1
uniprot id: A0A8B8U1F0
uniprot id: A0A8B8U1U2
uniprot id: A0A8B8U1U9
uniprot id: A0A8B8U2H2
uniprot id: A0A8B8U2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

419612:LOC102508490
gene id: 419612:LOC102508490
uniprot id: A0A8B8SLK2
names: Similarity
messages: Belongs to the SPT20 family.

419612:MRPS24
gene id: 419612:MRPS24
uniprot id: A0A8B8SBT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

419612:LOC102514258
gene id: 419612:LOC102514258
uniprot id: A0A8B7KDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SRXN1
gene id: 419612:SRXN1
uniprot id: A0A8B8RIZ8
uniprot id: A0A8B8RKT0
names: Similarity
messages: Belongs to the sulfiredoxin family.

419612:PPP2R5C
gene id: 419612:PPP2R5C
uniprot id: A0A8B6Y7Y8
uniprot id: A0A8B6YB92
uniprot id: A0A8B7K487
uniprot id: A0A8B8T8I1
uniprot id: A0A8B8T8I2
uniprot id: A0A8B8T8N3
uniprot id: A0A8B8T9I6
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

419612:LOC102507721
gene id: 419612:LOC102507721
uniprot id: A0A8B8SID5
names: Subcellular Location Annotation
messages: Nucleus

419612:IRF4
gene id: 419612:IRF4
uniprot id: A0A8B8RJZ2
uniprot id: A0A8B8RKA5
uniprot id: A0A8B8RLS0
names: Subcellular Location Annotation
messages: Nucleus

419612:PHOSPHO1
gene id: 419612:PHOSPHO1
uniprot id: A0A8B8R6T2
uniprot id: A0A8B8R6T7
uniprot id: A0A8B8R6Z8
uniprot id: A0A8B8R9J7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

419612:CITED2
gene id: 419612:CITED2
uniprot id: A0A8B8TFB6
uniprot id: A0A8B8TFC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

419612:LOC116656647
gene id: 419612:LOC116656647
uniprot id: A0A8B8R4Q2
uniprot id: A0A8B8R4Q6
uniprot id: A0A8B8R4X3
uniprot id: A0A8B8R6Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

419612:SHMT2
gene id: 419612:SHMT2
uniprot id: A0A8B6YDD5
uniprot id: A0A8B7K900
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

419612:LOC102521666
gene id: 419612:LOC102521666
uniprot id: A0A8B6YHI4
uniprot id: A0A8B8SA68
uniprot id: A0A8B8SA73
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

419612:WWP1
gene id: 419612:WWP1
uniprot id: A0A8B8S7Y0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102516364
gene id: 419612:LOC102516364
uniprot id: S9X248
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ARHGEF3
gene id: 419612:ARHGEF3
uniprot id: A0A8B6YFH3
uniprot id: A0A8B6YFT4
uniprot id: A0A8B6YJI9
uniprot id: A0A8B8R811
uniprot id: A0A8B8R813
uniprot id: A0A8B8RA55
uniprot id: A0A8B8RAV1
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

419612:CRHBP
gene id: 419612:CRHBP
uniprot id: A0A8B6YIK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

419612:MVK
gene id: 419612:MVK
uniprot id: A0A8B8SAP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

419612:MCM4
gene id: 419612:MCM4
uniprot id: A0A8B8S888
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

419612:HYLS1
gene id: 419612:HYLS1
uniprot id: A0A8B8SH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

419612:LOC102522620
gene id: 419612:LOC102522620
uniprot id: A0A8B7K5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FBP2
gene id: 419612:FBP2
uniprot id: S9WKB4
names: Similarity
messages: Belongs to the FBPase class 1 family.

419612:PSMD12
gene id: 419612:PSMD12
uniprot id: A0A8B6Y8M0
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

419612:ZFPL1
gene id: 419612:ZFPL1
uniprot id: A0A8B8TUW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZFPL1 family.
messages: Interacts with GOLGA2/GM130.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

419612:LOC102518488
gene id: 419612:LOC102518488
uniprot id: A0A8B6Y9F6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

419612:SEMA6C
gene id: 419612:SEMA6C
uniprot id: A0A8B8RQH2
uniprot id: A0A8B8RR35
uniprot id: A0A8B8RS71
uniprot id: A0A8B8RS76
uniprot id: A0A8B8RSH7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC116665730
gene id: 419612:LOC116665730
uniprot id: A0A8B8TIR9
names: Similarity
messages: Belongs to the NIBP family.

419612:SLX1A
gene id: 419612:SLX1A
uniprot id: A0A8B8REN0
uniprot id: A0A8B8REN1
uniprot id: A0A8B8REU7
uniprot id: A0A8B8RGL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

419612:LOC102520404
gene id: 419612:LOC102520404
uniprot id: A0A8B8RYE8
uniprot id: A0A8B8RZT7
uniprot id: A0A8B8S038
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: acrosome inner membrane

419612:KNG1
gene id: 419612:KNG1
uniprot id: A0A8B6YPY6
uniprot id: A0A8B8T8H0
names: Subcellular Location Annotation
messages: extracellular space

419612:CASTOR1
gene id: 419612:CASTOR1
uniprot id: A0A8B8SCG4
uniprot id: A0A8B8SDS1
names: Similarity
messages: Belongs to the GATS family.

419612:ARG1
gene id: 419612:ARG1
uniprot id: A0A8B8TF17
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

419612:DAZL
gene id: 419612:DAZL
uniprot id: A0A8B8TRC5
names: Subcellular Location Annotation
messages: Cytoplasm

419612:YKT6
gene id: 419612:YKT6
uniprot id: A0A8B6Y6T0
uniprot id: A0A8B8TD79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

419612:DGKI
gene id: 419612:DGKI
uniprot id: A0A8B8TAQ1
uniprot id: A0A8B8TAQ2
uniprot id: A0A8B8TAT9
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

419612:TTC38
gene id: 419612:TTC38
uniprot id: A0A8B8U1A5
names: Similarity
messages: Belongs to the TTC38 family.

419612:UCN
gene id: 419612:UCN
uniprot id: A0A8B8UEX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

419612:LOC102510305
gene id: 419612:LOC102510305
uniprot id: S9WNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102522293
gene id: 419612:LOC102522293
uniprot id: A0A8B8SFJ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:EXOG
gene id: 419612:EXOG
uniprot id: A0A8B6YC92
uniprot id: A0A8B8RAT2
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

419612:FOXF1
gene id: 419612:FOXF1
uniprot id: A0A8B6YE68
uniprot id: A0A8B8RR26
uniprot id: A0A8B8RSQ7
names: Subcellular Location Annotation
messages: Nucleus

419612:MPP7
gene id: 419612:MPP7
uniprot id: A0A8B6Y8R8
uniprot id: A0A8B8SI51
uniprot id: A0A8B8SKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: adherens junction
messages: tight junction

419612:HCRTR2
gene id: 419612:HCRTR2
uniprot id: A0A8B8RMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:XRN2
gene id: 419612:XRN2
uniprot id: A0A8B8RKF6
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

419612:LOC116660965
gene id: 419612:LOC116660965
uniprot id: A0A8B8SBK5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

419612:CSF3R
gene id: 419612:CSF3R
uniprot id: A0A8B6YKX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

419612:FAM13B
gene id: 419612:FAM13B
uniprot id: A0A8B8SRB9
uniprot id: A0A8B8SRC0
uniprot id: A0A8B8SRC5
uniprot id: A0A8B8SS21
uniprot id: A0A8B8SSF0
uniprot id: A0A8B8ST66
uniprot id: A0A8B8ST71
names: Similarity
messages: Belongs to the FAM13 family.

419612:TPPP2
gene id: 419612:TPPP2
uniprot id: A0A8B7KDZ3
names: Similarity
messages: Belongs to the TPPP family.

419612:ILKAP
gene id: 419612:ILKAP
uniprot id: A0A8B7K7L5
uniprot id: A0A8B8T2Q9
names: Similarity
messages: Belongs to the PP2C family.

419612:ITGA3
gene id: 419612:ITGA3
uniprot id: A0A8B8R6Q6
uniprot id: A0A8B8R8W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

419612:FTH1
gene id: 419612:FTH1
uniprot id: A0A8B8TT75
uniprot id: A0A8B8TU97
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:ACSF3
gene id: 419612:ACSF3
uniprot id: A0A8B8RRE8
uniprot id: A0A8B8RT30
uniprot id: A0A8B8RTE2
uniprot id: A0A8B8RTE6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

419612:LOC116663289
gene id: 419612:LOC116663289
uniprot id: S9XKA4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS21 family.

419612:GOLPH3L
gene id: 419612:GOLPH3L
uniprot id: A0A8B8RSM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

419612:LOC102521793
gene id: 419612:LOC102521793
uniprot id: A0A8B8U0D9
names: Similarity
messages: Belongs to the apolipoprotein L family.

419612:PGS1
gene id: 419612:PGS1
uniprot id: A0A8B8R3K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

419612:SLC7A9
gene id: 419612:SLC7A9
uniprot id: A0A8B6Y9K0
names: Subcellular Location Annotation
messages: Membrane

419612:RPP30
gene id: 419612:RPP30
uniprot id: A0A8B6YFP9
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

419612:IL22
gene id: 419612:IL22
uniprot id: A0A8B8U620
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Secreted

419612:LOC102513963
gene id: 419612:LOC102513963
uniprot id: A0A8B8TZ03
uniprot id: A0A8B8TZ05
uniprot id: A0A8B8TZ44
uniprot id: A0A8B8U009
uniprot id: A0A8B8U0B4
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

419612:NXPE4
gene id: 419612:NXPE4
uniprot id: A0A8B7K7Y3
names: Similarity
messages: Belongs to the NXPE family.

419612:FABP5
gene id: 419612:FABP5
uniprot id: A0A8B6YNF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

419612:ALG8
gene id: 419612:ALG8
uniprot id: A0A8B6YQD5
uniprot id: A0A8B8TQT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:PARL
gene id: 419612:PARL
uniprot id: A0A8B8TAN3
uniprot id: A0A8B8TAR2
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102513870
gene id: 419612:LOC102513870
uniprot id: A0A8B8R4V7
names: Subcellular Location Annotation
messages: Membrane

419612:HTR1A
gene id: 419612:HTR1A
uniprot id: S9Y7P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
messages: Membrane
messages: dendrite

419612:LOC116662665
gene id: 419612:LOC116662665
uniprot id: A0A8B8SSH8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

419612:ERCC4
gene id: 419612:ERCC4
uniprot id: A0A8B6YL21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

419612:CDH2
gene id: 419612:CDH2
uniprot id: A0A8B8RZL0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

419612:ZSCAN12
gene id: 419612:ZSCAN12
uniprot id: A0A8B7KEX1
names: Subcellular Location Annotation
messages: Nucleus

419612:RAD51D
gene id: 419612:RAD51D
uniprot id: A0A8B8R6N0
uniprot id: A0A8B8R6U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus

419612:HOXA3
gene id: 419612:HOXA3
uniprot id: A0A8B8TD08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

419612:MAPK8IP3
gene id: 419612:MAPK8IP3
uniprot id: A0A8B8RDE3
uniprot id: A0A8B8RDE7
uniprot id: A0A8B8RDF0
uniprot id: A0A8B8RDF1
uniprot id: A0A8B8RDF5
uniprot id: A0A8B8RDK3
uniprot id: A0A8B8RDK6
uniprot id: A0A8B8RDL2
uniprot id: A0A8B8RFG7
uniprot id: A0A8B8RFH1
uniprot id: A0A8B8RFH6
uniprot id: A0A8B8RFZ0
uniprot id: A0A8B8RFZ5
uniprot id: A0A8B8RG00
names: Similarity
messages: Belongs to the JIP scaffold family.

419612:XPA
gene id: 419612:XPA
uniprot id: S9XU48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

419612:UTRN
gene id: 419612:UTRN
uniprot id: A0A8B8TFG2
uniprot id: A0A8B8TFG3
uniprot id: A0A8B8TFG6
uniprot id: A0A8B8TFG7
uniprot id: A0A8B8TFG8
uniprot id: A0A8B8TFH4
uniprot id: A0A8B8TFH5
uniprot id: A0A8B8TFJ8
uniprot id: A0A8B8TFK8
uniprot id: A0A8B8TGU3
uniprot id: A0A8B8TGU9
names: Subcellular Location Annotation
messages: cytoskeleton

419612:BCAT2
gene id: 419612:BCAT2
uniprot id: A0A8B6Y663
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

419612:KCNJ11
gene id: 419612:KCNJ11
uniprot id: T0M9V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

419612:LOC102510644
gene id: 419612:LOC102510644
uniprot id: A0A8B7KDA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

419612:DIPK1A
gene id: 419612:DIPK1A
uniprot id: A0A8B8TL65
names: Similarity
messages: Belongs to the DIPK family.

419612:LOC102521092
gene id: 419612:LOC102521092
uniprot id: A0A8B8RNQ0
uniprot id: A0A8B8RP48
uniprot id: A0A8B8RQF0
uniprot id: A0A8B8RQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

419612:ITGAE
gene id: 419612:ITGAE
uniprot id: A0A8B8UH93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

419612:SGPL1
gene id: 419612:SGPL1
uniprot id: A0A8B6YC68
names: Similarity
messages: Belongs to the group II decarboxylase family.

419612:CAMSAP2
gene id: 419612:CAMSAP2
uniprot id: A0A8B8RXQ3
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

419612:POLR1B
gene id: 419612:POLR1B
uniprot id: A0A8B6YED4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

419612:PIK3CA
gene id: 419612:PIK3CA
uniprot id: A0A8B8TC13
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

419612:ITPK1
gene id: 419612:ITPK1
uniprot id: A0A8B8T8P1
uniprot id: A0A8B8T961
names: Similarity
messages: Belongs to the ITPK1 family.

419612:SSRP1
gene id: 419612:SSRP1
uniprot id: A0A8B8TQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

419612:SVOPL
gene id: 419612:SVOPL
uniprot id: A0A8B7KB52
uniprot id: A0A8B8TBW1
names: Subcellular Location Annotation
messages: Membrane

419612:DRAM2
gene id: 419612:DRAM2
uniprot id: A0A8B8TLS9
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102505666
gene id: 419612:LOC102505666
uniprot id: A0A8B7KES0
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

419612:SLC16A11
gene id: 419612:SLC16A11
uniprot id: A0A8B8UJA3
names: Subcellular Location Annotation
messages: Membrane

419612:ADHFE1
gene id: 419612:ADHFE1
uniprot id: A0A8B7KFQ9
uniprot id: A0A8B8S6C7
uniprot id: A0A8B8S7N5
uniprot id: A0A8B8S7U0
uniprot id: A0A8B8S8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

419612:LAMA2
gene id: 419612:LAMA2
uniprot id: A0A8B8TF13
uniprot id: A0A8B8TG90
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

419612:IP6K3
gene id: 419612:IP6K3
uniprot id: A0A8B8RLB8
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

419612:CA13
gene id: 419612:CA13
uniprot id: A0A8B6YNP4
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

419612:MCRIP2
gene id: 419612:MCRIP2
uniprot id: A0A8B8RF86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

419612:PTPRJ
gene id: 419612:PTPRJ
uniprot id: A0A8B8TRD7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

419612:PON1
gene id: 419612:PON1
uniprot id: A0A8B8TCA1
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

419612:LOC102503707
gene id: 419612:LOC102503707
uniprot id: A0A8B8T953
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:GLG1
gene id: 419612:GLG1
uniprot id: A0A8B8TK49
uniprot id: A0A8B8TK70
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

419612:LOC116660618
gene id: 419612:LOC116660618
uniprot id: A0A8B8S9A2
names: Similarity
messages: Belongs to the serpin family.

419612:TBXT
gene id: 419612:TBXT
uniprot id: A0A8B8TGG2
uniprot id: A0A8B8TGH4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

419612:SLC44A1
gene id: 419612:SLC44A1
uniprot id: A0A8B8SV87
uniprot id: A0A8B8SVH9
uniprot id: A0A8B8SVK2
uniprot id: A0A8B8SWP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

419612:ADGRL2
gene id: 419612:ADGRL2
uniprot id: A0A8B7K762
uniprot id: A0A8B8U7J8
uniprot id: A0A8B8U7K1
uniprot id: A0A8B8U8K5
uniprot id: A0A8B8U8L8
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102511866
gene id: 419612:LOC102511866
uniprot id: A0A8B8SJR5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

419612:MFSD14A
gene id: 419612:MFSD14A
uniprot id: A0A8B8TLG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

419612:RGS4
gene id: 419612:RGS4
uniprot id: S9YQI9
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

419612:PRRT1
gene id: 419612:PRRT1
uniprot id: A0A8B8RL11
names: Similarity
messages: Belongs to the CD225/Dispanin family.

419612:SS18L1
gene id: 419612:SS18L1
uniprot id: A0A8B8RHE5
uniprot id: A0A8B8RHF0
uniprot id: A0A8B8RHF1
uniprot id: A0A8B8RHF5
uniprot id: A0A8B8RHF6
uniprot id: A0A8B8RHM2
uniprot id: A0A8B8RHM8
uniprot id: A0A8B8RJC2
uniprot id: A0A8B8RJR7
uniprot id: A0A8B8RJS2
names: Similarity
messages: Belongs to the SS18 family.

419612:PRPF3
gene id: 419612:PRPF3
uniprot id: A0A8B6YL50
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

419612:POMT1
gene id: 419612:POMT1
uniprot id: A0A8B8SX17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

419612:IL2RA
gene id: 419612:IL2RA
uniprot id: A0A8B8SHZ5
uniprot id: A0A8B8SJA8
names: Caution
names: Function
names: Subunit
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

419612:CDC37
gene id: 419612:CDC37
uniprot id: A0A8B6YBV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

419612:INPP5A
gene id: 419612:INPP5A
uniprot id: A0A8B8TW17
uniprot id: A0A8B8TW18
uniprot id: A0A8B8TW31
uniprot id: A0A8B8TX49
uniprot id: A0A8B8TXF7
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

419612:UTP18
gene id: 419612:UTP18
uniprot id: A0A8B8UI17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

419612:LOC102506819
gene id: 419612:LOC102506819
uniprot id: A0A8B8U2Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC106728837
gene id: 419612:LOC106728837
uniprot id: A0A8B8SAD3
uniprot id: A0A8B8SBK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

419612:FAAH
gene id: 419612:FAAH
uniprot id: A0A8B8U654
names: Similarity
messages: Belongs to the amidase family.

419612:ZHX3
gene id: 419612:ZHX3
uniprot id: A0A8B8RLL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

419612:LOC102509173
gene id: 419612:LOC102509173
uniprot id: A0A8B7K9B5
names: Subcellular Location Annotation
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:BAAT
gene id: 419612:BAAT
uniprot id: A0A8B6YH38
uniprot id: A0A8B7KAL5
uniprot id: A0A8B8SVF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C/M/P thioester hydrolase family.
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

419612:ZNF483
gene id: 419612:ZNF483
uniprot id: A0A8B7K5K9
names: Subcellular Location Annotation
messages: Nucleus

419612:BCAN
gene id: 419612:BCAN
uniprot id: A0A8B8RPN7
uniprot id: A0A8B8RPN9
uniprot id: A0A8B8RQ65
uniprot id: A0A8B8RQ71
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:LOC102509461
gene id: 419612:LOC102509461
uniprot id: A0A8B8SYU4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

419612:LOC102511575
gene id: 419612:LOC102511575
uniprot id: A0A8B8RIS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

419612:FEV
gene id: 419612:FEV
uniprot id: A0A8B8T375
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:PRSS16
gene id: 419612:PRSS16
uniprot id: A0A8B8RN74
uniprot id: A0A8B8RPK1
names: Similarity
messages: Belongs to the peptidase S28 family.

419612:MYCL
gene id: 419612:MYCL
uniprot id: A0A8B8U6J4
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

419612:DLGAP3
gene id: 419612:DLGAP3
uniprot id: A0A8B8UAZ8
names: Similarity
messages: Belongs to the SAPAP family.

419612:B4GALNT1
gene id: 419612:B4GALNT1
uniprot id: A0A8B8U4D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:KCNK10
gene id: 419612:KCNK10
uniprot id: A0A8B6YME3
uniprot id: A0A8B6YPP9
uniprot id: A0A8B8T7Z2
uniprot id: A0A8B8T850
uniprot id: A0A8B8T8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

419612:LMLN
gene id: 419612:LMLN
uniprot id: A0A8B6YB95
uniprot id: A0A8B8T4I7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

419612:UBE2A
gene id: 419612:UBE2A
uniprot id: A0A8B8SPC4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:PIAS3
gene id: 419612:PIAS3
uniprot id: A0A8B8RRF6
names: Similarity
messages: Belongs to the PIAS family.

419612:LOC102506817
gene id: 419612:LOC102506817
uniprot id: A0A8B6YG81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102508956
gene id: 419612:LOC102508956
uniprot id: A0A8B6YP42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:DPH6
gene id: 419612:DPH6
uniprot id: A0A8B8T5C3
uniprot id: A0A8B8T5Z2
uniprot id: A0A8B8T649
names: Function
names: Similarity
messages: Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.
messages: Belongs to the Diphthine--ammonia ligase family.

419612:CORO1A
gene id: 419612:CORO1A
uniprot id: A0A8B6YF00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat coronin family.
messages: Binds actin.
messages: Membrane
messages: cell cortex
messages: cytoskeleton
messages: phagosome membrane

419612:LOC102509158
gene id: 419612:LOC102509158
uniprot id: A0A8B8SK46
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

419612:LOC102505952
gene id: 419612:LOC102505952
uniprot id: A0A8B6YAS9
uniprot id: A0A8B8RGD4
names: Similarity
messages: Belongs to the peptidase C14A family.

419612:LDB2
gene id: 419612:LDB2
uniprot id: A0A8B8U6V3
uniprot id: A0A8B8U7S2
uniprot id: A0A8B8U7T9
uniprot id: A0A8B8U7X4
names: Similarity
messages: Belongs to the LDB family.

419612:GTF3C5
gene id: 419612:GTF3C5
uniprot id: A0A8B8SYC2
names: Subcellular Location Annotation
messages: Nucleus

419612:CDKAL1
gene id: 419612:CDKAL1
uniprot id: A0A8B7K894
uniprot id: A0A8B8RKK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

419612:SHANK3
gene id: 419612:SHANK3
uniprot id: A0A8B8U1S8
uniprot id: A0A8B8U1T4
uniprot id: A0A8B8U2A0
uniprot id: A0A8B8U2A5
uniprot id: A0A8B8U319
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
messages: Postsynaptic density

419612:SERINC4
gene id: 419612:SERINC4
uniprot id: A0A8B7K6E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

419612:LOC102510900
gene id: 419612:LOC102510900
uniprot id: A0A8B8RWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: nucleolus

419612:SLC35F4
gene id: 419612:SLC35F4
uniprot id: A0A8B8T6V5
uniprot id: A0A8B8T748
uniprot id: A0A8B8T7S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

419612:SMARCA5
gene id: 419612:SMARCA5
uniprot id: A0A8B6YHQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

419612:CACNB1
gene id: 419612:CACNB1
uniprot id: A0A8B7K486
uniprot id: A0A8B8R734
uniprot id: A0A8B8R791
uniprot id: A0A8B8R973
uniprot id: S9X9Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

419612:LOC102507115
gene id: 419612:LOC102507115
uniprot id: S9WD84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:DNAH5
gene id: 419612:DNAH5
uniprot id: A0A8B8S8G5
names: Similarity
messages: Belongs to the dynein heavy chain family.

419612:ID4
gene id: 419612:ID4
uniprot id: A0A8B8RMB0
names: Subcellular Location Annotation
messages: Nucleus

419612:TRUB2
gene id: 419612:TRUB2
uniprot id: A0A8B6YGX3
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

419612:BET1
gene id: 419612:BET1
uniprot id: A0A8B8TCB2
names: Subcellular Location Annotation
messages: Membrane

419612:INIP
gene id: 419612:INIP
uniprot id: A0A8B7K3M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

419612:ALDH6A1
gene id: 419612:ALDH6A1
uniprot id: A0A8B6YGF3
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

419612:PPIP5K2
gene id: 419612:PPIP5K2
uniprot id: A0A8B6YHA6
uniprot id: A0A8B6YIJ5
uniprot id: A0A8B7KDA4
uniprot id: A0A8B8SQ74
uniprot id: A0A8B8SQ79
uniprot id: A0A8B8SQ85
uniprot id: A0A8B8SQ95
uniprot id: A0A8B8SQA0
uniprot id: A0A8B8SR07
uniprot id: A0A8B8SR16
uniprot id: A0A8B8SRE2
uniprot id: A0A8B8SRE6
uniprot id: A0A8B8SRF1
uniprot id: A0A8B8SS84
uniprot id: A0A8B8SS89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

419612:DDX31
gene id: 419612:DDX31
uniprot id: A0A8B8SXG8
uniprot id: A0A8B8SYA8
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

419612:LOC102513272
gene id: 419612:LOC102513272
uniprot id: A0A8B8R7B2
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

419612:PKM
gene id: 419612:PKM
uniprot id: A0A8B8S5T0
uniprot id: A0A8B8S673
names: Similarity
messages: Belongs to the pyruvate kinase family.

419612:DOCK9
gene id: 419612:DOCK9
uniprot id: A0A8B6YT01
uniprot id: A0A8B7KGG8
uniprot id: A0A8B7KGK0
uniprot id: A0A8B7KGK5
uniprot id: A0A8B7KGR9
uniprot id: A0A8B7KHT0
uniprot id: A0A8B7KHT6
uniprot id: A0A8B7KIK9
uniprot id: A0A8B8UDG0
uniprot id: A0A8B8UDG3
uniprot id: A0A8B8UDG5
uniprot id: A0A8B8UE70
uniprot id: A0A8B8UE86
uniprot id: A0A8B8UET0
uniprot id: A0A8B8UET9
names: Similarity
messages: Belongs to the DOCK family.

419612:FLCN
gene id: 419612:FLCN
uniprot id: A0A8B8UL39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

419612:LOC102516700
gene id: 419612:LOC102516700
uniprot id: A0A8B6YE73
uniprot id: A0A8B7K8G7
uniprot id: A0A8B8S584
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

419612:CDH20
gene id: 419612:CDH20
uniprot id: A0A8B8S848
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

419612:LOC102505363
gene id: 419612:LOC102505363
uniprot id: A0A8B6YFA8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:NUDT6
gene id: 419612:NUDT6
uniprot id: A0A8B8RLI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

419612:CEP162
gene id: 419612:CEP162
uniprot id: A0A8B6YB60
uniprot id: A0A8B8TDX2
uniprot id: A0A8B8TE20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

419612:INSL6
gene id: 419612:INSL6
uniprot id: A0A8B6Y7B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

419612:STAT6
gene id: 419612:STAT6
uniprot id: A0A8B6YD40
uniprot id: A0A8B6YD42
uniprot id: A0A8B7K8N3
uniprot id: A0A8B8U4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

419612:SPEM1
gene id: 419612:SPEM1
uniprot id: A0A8B6Y8W0
names: Subcellular Location Annotation
messages: Membrane

419612:ENPP3
gene id: 419612:ENPP3
uniprot id: A0A8B6YFU6
names: Subcellular Location Annotation
messages: Secreted

419612:LOC102513548
gene id: 419612:LOC102513548
uniprot id: A0A8B6YCB6
names: Similarity
messages: Belongs to the NDK family.

419612:SIX1
gene id: 419612:SIX1
uniprot id: S9WWC6
names: Subcellular Location Annotation
messages: Nucleus

419612:GTF2E2
gene id: 419612:GTF2E2
uniprot id: A0A8B8S304
uniprot id: A0A8B8S4C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

419612:SPIRE2
gene id: 419612:SPIRE2
uniprot id: A0A8B8RT92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

419612:LOC106728773
gene id: 419612:LOC106728773
uniprot id: S9XQF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CNN1
gene id: 419612:CNN1
uniprot id: T0MGK6
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

419612:ZSCAN25
gene id: 419612:ZSCAN25
uniprot id: A0A8B8REG8
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102510375
gene id: 419612:LOC102510375
uniprot id: A0A8B8TMT2
uniprot id: A0A8B8TN98
uniprot id: A0A8B8TNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Membrane

419612:GUF1
gene id: 419612:GUF1
uniprot id: A0A8B8UDW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

419612:LRRC8A
gene id: 419612:LRRC8A
uniprot id: S9YGT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

419612:LOC102517112
gene id: 419612:LOC102517112
uniprot id: A0A8B8TWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:GORASP1
gene id: 419612:GORASP1
uniprot id: A0A8B8RAT5
names: Similarity
messages: Belongs to the GORASP family.

419612:STXBP5
gene id: 419612:STXBP5
uniprot id: A0A8B6YG08
uniprot id: A0A8B6YG21
uniprot id: A0A8B7KAH9
uniprot id: A0A8B8TFJ2
uniprot id: A0A8B8TFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

419612:PNN
gene id: 419612:PNN
uniprot id: A0A8B6YI99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

419612:LOC102509204
gene id: 419612:LOC102509204
uniprot id: A0A8B6Y6X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PPA2
gene id: 419612:PPA2
uniprot id: A0A8B8RIE4
uniprot id: A0A8B8RIV8
names: Similarity
messages: Belongs to the PPase family.

419612:SLC9A6
gene id: 419612:SLC9A6
uniprot id: A0A8B8SKP4
uniprot id: A0A8B8SL08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

419612:LOC116661917
gene id: 419612:LOC116661917
uniprot id: A0A8B8SK94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

419612:TXLNA
gene id: 419612:TXLNA
uniprot id: A0A8B8UC39
names: Similarity
messages: Belongs to the taxilin family.

419612:SLC39A4
gene id: 419612:SLC39A4
uniprot id: A0A8B8S1Q0
uniprot id: A0A8B8S317
uniprot id: A0A8B8S3B4
uniprot id: A0A8B8S3E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

419612:CGAS
gene id: 419612:CGAS
uniprot id: A0A8B8RE07
uniprot id: A0A8B8RE70
names: Similarity
messages: Belongs to the mab-21 family.

419612:LOC102518431
gene id: 419612:LOC102518431
uniprot id: A0A8B8TED2
uniprot id: A0A8B8TED7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:C9H16orf70
gene id: 419612:C9H16orf70
uniprot id: A0A8B8TKQ7
names: Similarity
messages: Belongs to the PHAF1 family.

419612:GAPDHS
gene id: 419612:GAPDHS
uniprot id: A0A8B6YF20
uniprot id: A0A8B8TP09
uniprot id: A0A8B8TPM8
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

419612:LOC102522359
gene id: 419612:LOC102522359
uniprot id: A0A8B6Y9E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CCNB2
gene id: 419612:CCNB2
uniprot id: A0A8B8T3X6
names: Similarity
messages: Belongs to the cyclin family.

419612:UTS2B
gene id: 419612:UTS2B
uniprot id: A0A8B6YJD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

419612:LMLN2
gene id: 419612:LMLN2
uniprot id: A0A8B8TA67
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

419612:NUP35
gene id: 419612:NUP35
uniprot id: A0A8B6YJK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

419612:ZSCAN21
gene id: 419612:ZSCAN21
uniprot id: A0A8B8REX5
names: Subcellular Location Annotation
messages: Nucleus

419612:SHOX2
gene id: 419612:SHOX2
uniprot id: A0A8B8TGV8
uniprot id: A0A8B8TGW4
uniprot id: A0A8B8TI53
names: Subcellular Location Annotation
messages: Nucleus

419612:CEMIP
gene id: 419612:CEMIP
uniprot id: A0A8B8S4N1
uniprot id: A0A8B8S5Y7
uniprot id: A0A8B8S6M3
names: Similarity
messages: Belongs to the CEMIP family.

419612:EVA1A
gene id: 419612:EVA1A
uniprot id: A0A8B8SL20
names: Similarity
messages: Belongs to the EVA1 family.

419612:LOC102508999
gene id: 419612:LOC102508999
uniprot id: A0A8B8SFT5
names: Function
messages: Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.

419612:ALOX12
gene id: 419612:ALOX12
uniprot id: A0A8B8UJC0
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:ZCCHC4
gene id: 419612:ZCCHC4
uniprot id: A0A8B8U8W2
uniprot id: A0A8B8U8Y4
uniprot id: A0A8B8U9U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC4 family.
messages: Cytoplasm
messages: nucleolus

419612:LDHB
gene id: 419612:LDHB
uniprot id: A0A8B6YF77
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

419612:LOC102524424
gene id: 419612:LOC102524424
uniprot id: A0A8B8U2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:HOXA11
gene id: 419612:HOXA11
uniprot id: A0A8B8TBS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

419612:NOS2
gene id: 419612:NOS2
uniprot id: A0A8B6YFW5
uniprot id: A0A8B8R8J4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

419612:ARRDC5
gene id: 419612:ARRDC5
uniprot id: S9XF64
names: Similarity
messages: Belongs to the arrestin family.

419612:CNOT6
gene id: 419612:CNOT6
uniprot id: A0A8B8RS25
uniprot id: A0A8B8RU13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

419612:CTSO
gene id: 419612:CTSO
uniprot id: A0A8B8RX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

419612:UXS1
gene id: 419612:UXS1
uniprot id: A0A8B8SJ29
uniprot id: A0A8B8SKG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

419612:SAMM50
gene id: 419612:SAMM50
uniprot id: A0A8B8U238
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

419612:HDAC5
gene id: 419612:HDAC5
uniprot id: A0A8B7KDU1
uniprot id: A0A8B8R5E0
uniprot id: A0A8B8R5E3
uniprot id: A0A8B8R5L0
uniprot id: A0A8B8R7L4
uniprot id: A0A8B8R843
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

419612:SNRPE
gene id: 419612:SNRPE
uniprot id: A0A8B6Y9L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

419612:LOC102520594
gene id: 419612:LOC102520594
uniprot id: A0A8B7KGG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ALX1
gene id: 419612:ALX1
uniprot id: A0A8B8U4S1
uniprot id: A0A8B8U5K3
names: Subcellular Location Annotation
messages: Nucleus

419612:KMT2B
gene id: 419612:KMT2B
uniprot id: A0A8B8TP66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
messages: Nucleus

419612:GPC6
gene id: 419612:GPC6
uniprot id: A0A8B8UDL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

419612:JPH3
gene id: 419612:JPH3
uniprot id: A0A8B8RT29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

419612:DPAGT1
gene id: 419612:DPAGT1
uniprot id: A0A8B8SDQ6
uniprot id: S9YVF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:LOC102518472
gene id: 419612:LOC102518472
uniprot id: A0A8B7KE79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102507912
gene id: 419612:LOC102507912
uniprot id: A0A8B7KDZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

419612:ADNP
gene id: 419612:ADNP
uniprot id: A0A8B6Y6P8
uniprot id: A0A8B6Y8D2
uniprot id: A0A8B8RJ04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Nucleus
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

419612:PCSK6
gene id: 419612:PCSK6
uniprot id: A0A8B8S5P3
names: Similarity
messages: Belongs to the peptidase S8 family.

419612:PRDM12
gene id: 419612:PRDM12
uniprot id: A0A8B8SX35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

419612:SSR2
gene id: 419612:SSR2
uniprot id: A0A8B6Y757
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

419612:SLC16A9
gene id: 419612:SLC16A9
uniprot id: A0A8B7K8X0
uniprot id: A0A8B8TYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane

419612:UCN2
gene id: 419612:UCN2
uniprot id: A0A8B8R939
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

419612:PCMTD1
gene id: 419612:PCMTD1
uniprot id: A0A8B8S878
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

419612:EXOC6
gene id: 419612:EXOC6
uniprot id: A0A8B8TY23
uniprot id: A0A8B8TZ22
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

419612:ALX4
gene id: 419612:ALX4
uniprot id: A0A8B6YEW4
names: Subcellular Location Annotation
messages: Nucleus

419612:GK5
gene id: 419612:GK5
uniprot id: A0A8B8TLE9
uniprot id: A0A8B8TMN6
names: Similarity
messages: Belongs to the FGGY kinase family.

419612:LOC116661570
gene id: 419612:LOC116661570
uniprot id: A0A8B8SI08
names: Similarity
messages: Belongs to the aldo/keto reductase family.

419612:ATP2A3
gene id: 419612:ATP2A3
uniprot id: A0A8B8UH05
uniprot id: A0A8B8UHL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

419612:ALDH4A1
gene id: 419612:ALDH4A1
uniprot id: A0A8B6YIL3
uniprot id: A0A8B8UA56
uniprot id: A0A8B8UA97
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

419612:CHURC1
gene id: 419612:CHURC1
uniprot id: A0A8B7K7I8
names: Similarity
messages: Belongs to the Churchill family.

419612:NOP14
gene id: 419612:NOP14
uniprot id: A0A8B8U2H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

419612:TMEM229B
gene id: 419612:TMEM229B
uniprot id: A0A8B7KBC1
uniprot id: A0A8B7KBW0
uniprot id: A0A8B8T7G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

419612:LOC102521215
gene id: 419612:LOC102521215
uniprot id: A0A8B6YNF7
names: Similarity
messages: Belongs to the MS4A family.

419612:TSPAN8
gene id: 419612:TSPAN8
uniprot id: A0A8B8U4Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:RALYL
gene id: 419612:RALYL
uniprot id: A0A8B8S7K0
uniprot id: A0A8B8S8Z8
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

419612:TF
gene id: 419612:TF
uniprot id: A0A8B6YBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

419612:DLGAP1
gene id: 419612:DLGAP1
uniprot id: A0A8B8RZN0
uniprot id: A0A8B8RZP3
uniprot id: A0A8B8S103
uniprot id: A0A8B8S175
uniprot id: A0A8B8S198
names: Similarity
messages: Belongs to the SAPAP family.

419612:HYAL1
gene id: 419612:HYAL1
uniprot id: A0A8B6Y7L3
uniprot id: A0A8B6Y9Y7
uniprot id: A0A8B7KD73
uniprot id: A0A8B7KDH4
uniprot id: A0A8B7KEG5
uniprot id: A0A8B8RBF8
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

419612:LOC102524290
gene id: 419612:LOC102524290
uniprot id: A0A8B8RWB4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FABP2
gene id: 419612:FABP2
uniprot id: A0A8B6YGF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

419612:SSPOP
gene id: 419612:SSPOP
uniprot id: A0A8B8TB73
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

419612:SLC7A13
gene id: 419612:SLC7A13
uniprot id: A0A8B8S6E5
names: Subcellular Location Annotation
messages: Membrane

419612:RPRD1A
gene id: 419612:RPRD1A
uniprot id: A0A8B6YIB1
uniprot id: A0A8B7KB56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Nucleus

419612:DES
gene id: 419612:DES
uniprot id: A0A8B6YHS9
uniprot id: A0A8B8T1R7
names: Similarity
messages: Belongs to the intermediate filament family.

419612:TBPL2
gene id: 419612:TBPL2
uniprot id: A0A8B8T738
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

419612:DMRTB1
gene id: 419612:DMRTB1
uniprot id: A0A8B8U7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

419612:DLC1
gene id: 419612:DLC1
uniprot id: A0A8B6YEE1
uniprot id: A0A8B8S2U4
uniprot id: A0A8B8S2U7
uniprot id: A0A8B8S465
uniprot id: A0A8B8S4F5
names: Subcellular Location Annotation
messages: Cytoplasm

419612:ANXA4
gene id: 419612:ANXA4
uniprot id: A0A8B8UGC5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

419612:GTF2B
gene id: 419612:GTF2B
uniprot id: A0A8B6YM03
names: Similarity
messages: Belongs to the TFIIB family.

419612:PFKFB2
gene id: 419612:PFKFB2
uniprot id: A0A8B8RYD4
uniprot id: A0A8B8RZS4
uniprot id: A0A8B8RZU1
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

419612:LOC102504084
gene id: 419612:LOC102504084
uniprot id: A0A8B6YF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

419612:DOCK2
gene id: 419612:DOCK2
uniprot id: A0A8B7KFM9
uniprot id: A0A8B8RST8
names: Similarity
messages: Belongs to the DOCK family.

419612:ERF
gene id: 419612:ERF
uniprot id: A0A8B8TI12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:MIF
gene id: 419612:MIF
uniprot id: A0A8B7K4U3
names: Similarity
messages: Belongs to the MIF family.

419612:RAF1
gene id: 419612:RAF1
uniprot id: A0A8B8RA77
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

419612:TPD52L1
gene id: 419612:TPD52L1
uniprot id: A0A8B8TEP6
uniprot id: A0A8B8TEQ2
uniprot id: A0A8B8TEQ5
uniprot id: A0A8B8TEU6
uniprot id: A0A8B8TG11
uniprot id: A0A8B8TG18
names: Similarity
messages: Belongs to the TPD52 family.

419612:MYRF
gene id: 419612:MYRF
uniprot id: A0A8B8TT40
uniprot id: A0A8B8TT45
uniprot id: A0A8B8TT52
uniprot id: A0A8B8TT57
uniprot id: A0A8B8TT58
uniprot id: A0A8B8TT62
uniprot id: A0A8B8TU69
uniprot id: A0A8B8TU74
uniprot id: A0A8B8TU79
uniprot id: A0A8B8TU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

419612:LYPLAL1
gene id: 419612:LYPLAL1
uniprot id: A0A8B6YIS5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

419612:DCLRE1C
gene id: 419612:DCLRE1C
uniprot id: A0A8B8SHR1
uniprot id: A0A8B8SHR8
uniprot id: A0A8B8SHS3
uniprot id: A0A8B8SIU3
uniprot id: A0A8B8SIU8
uniprot id: A0A8B8SJ11
uniprot id: A0A8B8SJ17
uniprot id: A0A8B8SK75
uniprot id: A0A8B8SK80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

419612:LOC102522069
gene id: 419612:LOC102522069
uniprot id: A0A8B8TND8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

419612:CCNE1
gene id: 419612:CCNE1
uniprot id: A0A8B8TIV6
names: Similarity
messages: Belongs to the cyclin family.

419612:LOC116660617
gene id: 419612:LOC116660617
uniprot id: A0A8B8SA80
names: Similarity
messages: Belongs to the serpin family.

419612:TMC1
gene id: 419612:TMC1
uniprot id: A0A8B8SUE4
uniprot id: A0A8B8SUF5
uniprot id: A0A8B8SUL3
uniprot id: A0A8B8SUL8
uniprot id: A0A8B8SUM4
uniprot id: A0A8B8SUN0
uniprot id: A0A8B8SUU8
uniprot id: A0A8B8SV89
uniprot id: A0A8B8SV94
uniprot id: A0A8B8SV99
uniprot id: A0A8B8SVX3
uniprot id: A0A8B8SVY1
uniprot id: A0A8B8SVZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:TSPAN7
gene id: 419612:TSPAN7
uniprot id: A0A8B8SQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:NAP1L2
gene id: 419612:NAP1L2
uniprot id: S9XEG5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

419612:CRMP1
gene id: 419612:CRMP1
uniprot id: A0A8B8U4W6
uniprot id: A0A8B8U4X6
uniprot id: A0A8B8U4Y1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

419612:KIF13A
gene id: 419612:KIF13A
uniprot id: A0A8B8RKH1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:USP27X
gene id: 419612:USP27X
uniprot id: A0A8B8SL36
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

419612:AMPD1
gene id: 419612:AMPD1
uniprot id: A0A8B6YN29
uniprot id: A0A8B8TKU5
uniprot id: A0A8B8TM37
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

419612:PRPF4
gene id: 419612:PRPF4
uniprot id: A0A8B6YPG1
uniprot id: A0A8B6YSV3
uniprot id: A0A8B7KGC1
uniprot id: A0A8B8SWY8
names: Subcellular Location Annotation
messages: Nucleus speckle

419612:LOC102514126
gene id: 419612:LOC102514126
uniprot id: A0A8B8SP60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

419612:SLC5A3
gene id: 419612:SLC5A3
uniprot id: T0MIX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

419612:SIVA1
gene id: 419612:SIVA1
uniprot id: A0A8B8T929
uniprot id: A0A8B8T9Y8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
messages: Nucleus

419612:KRT2
gene id: 419612:KRT2
uniprot id: A0A8B8U3J0
names: Similarity
messages: Belongs to the intermediate filament family.

419612:KCNK15
gene id: 419612:KCNK15
uniprot id: A0A8B8RGF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

419612:MBP
gene id: 419612:MBP
uniprot id: A0A8B8S7R8
uniprot id: A0A8B8S7S7
uniprot id: A0A8B8S973
uniprot id: A0A8B8S9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

419612:NDFIP1
gene id: 419612:NDFIP1
uniprot id: A0A8B8SRY8
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

419612:LOC102520159
gene id: 419612:LOC102520159
uniprot id: A0A8B6YM87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

419612:HAUS1
gene id: 419612:HAUS1
uniprot id: A0A8B8S7P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

419612:BTF3
gene id: 419612:BTF3
uniprot id: A0A8B8SJZ6
uniprot id: A0A8B8SK01
names: Similarity
messages: Belongs to the NAC-beta family.

419612:ACAN
gene id: 419612:ACAN
uniprot id: A0A8B7KGC7
uniprot id: A0A8B8S3U4
uniprot id: A0A8B8S5R0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:LOC102520324
gene id: 419612:LOC102520324
uniprot id: A0A8B7KGT2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

419612:BPNT2
gene id: 419612:BPNT2
uniprot id: A0A8B8S7A8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

419612:TFDP1
gene id: 419612:TFDP1
uniprot id: A0A8B8UDS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

419612:NRN1
gene id: 419612:NRN1
uniprot id: A0A8B8RLZ3
names: Similarity
messages: Belongs to the neuritin family.

419612:COL4A1
gene id: 419612:COL4A1
uniprot id: A0A8B8UE00
uniprot id: A0A8B8UE17
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

419612:LOC102521804
gene id: 419612:LOC102521804
uniprot id: S9WX72
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:GJA3
gene id: 419612:GJA3
uniprot id: A0A8B8UDN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

419612:LOC116660215
gene id: 419612:LOC116660215
uniprot id: A0A8B8S567
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

419612:UBAC2
gene id: 419612:UBAC2
uniprot id: A0A8B7KGS5
uniprot id: A0A8B7KIL3
names: Subcellular Location Annotation
messages: Membrane

419612:CSF2
gene id: 419612:CSF2
uniprot id: A0A8B6YF38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GM-CSF family.
messages: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
messages: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.
messages: Secreted

419612:ANXA2
gene id: 419612:ANXA2
uniprot id: A0A8B8T479
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
messages: Membrane
messages: basement membrane

419612:IHH
gene id: 419612:IHH
uniprot id: A0A8B7KBQ3
uniprot id: A0A8B8T1L8
uniprot id: A0A8B8T2H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

419612:TAX1BP3
gene id: 419612:TAX1BP3
uniprot id: S9XQ10
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
messages: Nucleus

419612:LOC102521129
gene id: 419612:LOC102521129
uniprot id: A0A8B8SSQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MRGBP
gene id: 419612:MRGBP
uniprot id: A0A8B8RHS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

419612:BORCS8
gene id: 419612:BORCS8
uniprot id: A0A8B8RT01
uniprot id: A0A8B8RUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS8 family.
messages: Lysosome membrane
messages: Membrane

419612:LOC102519317
gene id: 419612:LOC102519317
uniprot id: S9YE76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SFT2D3
gene id: 419612:SFT2D3
uniprot id: A0A8B8SZ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

419612:STAMBPL1
gene id: 419612:STAMBPL1
uniprot id: A0A8B8TY72
uniprot id: A0A8B8TY79
names: Similarity
messages: Belongs to the peptidase M67C family.

419612:ACO1
gene id: 419612:ACO1
uniprot id: A0A8B8SV84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

419612:CAPN2
gene id: 419612:CAPN2
uniprot id: A0A8B8RYU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

419612:LOC102512839
gene id: 419612:LOC102512839
uniprot id: A0A8B7KHW4
names: Subcellular Location Annotation
messages: Membrane

419612:FTMT
gene id: 419612:FTMT
uniprot id: A0A8B8SQN2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:MAB21L2
gene id: 419612:MAB21L2
uniprot id: S9W853
names: Similarity
messages: Belongs to the mab-21 family.

419612:MAP4K5
gene id: 419612:MAP4K5
uniprot id: A0A8B8T6M2
uniprot id: A0A8B8T7H4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

419612:ETFB
gene id: 419612:ETFB
uniprot id: A0A8B8TNG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

419612:NPVF
gene id: 419612:NPVF
uniprot id: A0A8B6Y768
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

419612:ATF7
gene id: 419612:ATF7
uniprot id: A0A8B8U2P5
uniprot id: A0A8B8U2Q1
uniprot id: A0A8B8U390
uniprot id: A0A8B8U396
uniprot id: A0A8B8U3P6
uniprot id: A0A8B8U3Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

419612:BLM
gene id: 419612:BLM
uniprot id: A0A8B6YMM1
uniprot id: A0A8B7KH80
uniprot id: A0A8B8S3K3
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

419612:LOC102519813
gene id: 419612:LOC102519813
uniprot id: A0A8B8U534
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

419612:CFAP97
gene id: 419612:CFAP97
uniprot id: A0A8B8S2B6
names: Similarity
messages: Belongs to the CFAP97 family.

419612:EFNB3
gene id: 419612:EFNB3
uniprot id: A0A8B6Y818
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102515026
gene id: 419612:LOC102515026
uniprot id: A0A8B8S8T7
uniprot id: A0A8B8S906
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

419612:KCNE2
gene id: 419612:KCNE2
uniprot id: T0NLP2
names: Similarity
messages: Belongs to the potassium channel KCNE family.

419612:HOXD13
gene id: 419612:HOXD13
uniprot id: A0A8B6YK39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

419612:TSR1
gene id: 419612:TSR1
uniprot id: A0A8B6YGX2
uniprot id: A0A8B6YJP7
names: Subcellular Location Annotation
messages: nucleolus

419612:LMNB1
gene id: 419612:LMNB1
uniprot id: A0A8B8SRI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

419612:SCARF2
gene id: 419612:SCARF2
uniprot id: A0A8B8SAG4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102515085
gene id: 419612:LOC102515085
uniprot id: A0A8B8T7M4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102520356
gene id: 419612:LOC102520356
uniprot id: A0A8B6YBP3
names: Similarity
messages: Belongs to the MHC class II family.

419612:LOC102510635
gene id: 419612:LOC102510635
uniprot id: A0A8B8ST42
uniprot id: S9YRQ6
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

419612:LRRC7
gene id: 419612:LRRC7
uniprot id: A0A8B6YPT2
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

419612:SLC45A1
gene id: 419612:SLC45A1
uniprot id: A0A8B8U8T9
uniprot id: A0A8B8U9M7
names: Subcellular Location Annotation
messages: Membrane

419612:TMCO3
gene id: 419612:TMCO3
uniprot id: A0A8B8UEB9
names: Subcellular Location Annotation
messages: Membrane

419612:CORO6
gene id: 419612:CORO6
uniprot id: A0A8B8R613
uniprot id: A0A8B8R616
uniprot id: A0A8B8R671
uniprot id: A0A8B8R880
names: Similarity
messages: Belongs to the WD repeat coronin family.

419612:LOC116666628
gene id: 419612:LOC116666628
uniprot id: A0A8B8TVM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:GAB2
gene id: 419612:GAB2
uniprot id: A0A8B8TQU0
uniprot id: A0A8B8TQU3
uniprot id: A0A8B8TRK2
names: Similarity
messages: Belongs to the GAB family.

419612:C26H4orf47
gene id: 419612:C26H4orf47
uniprot id: A0A8B7K656
uniprot id: A0A8B8S355
uniprot id: A0A8B8S4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP96 family.
messages: centrosome

419612:KCNH7
gene id: 419612:KCNH7
uniprot id: A0A8B8SZM3
uniprot id: A0A8B8T035
uniprot id: A0A8B8T046
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

419612:CPB2
gene id: 419612:CPB2
uniprot id: A0A8B6YI40
names: Similarity
messages: Belongs to the peptidase M14 family.

419612:PGLYRP1
gene id: 419612:PGLYRP1
uniprot id: A0A8B6YL77
names: Function
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
messages: Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems.

419612:SLC30A9
gene id: 419612:SLC30A9
uniprot id: A0A8B8UDK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

419612:GPX8
gene id: 419612:GPX8
uniprot id: A0A8B6YGS8
uniprot id: A0A8B8SEE2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

419612:CES4A
gene id: 419612:CES4A
uniprot id: A0A8B6YC57
uniprot id: A0A8B8TJF8
uniprot id: A0A8B8TJH2
uniprot id: A0A8B8TJN9
uniprot id: A0A8B8TKP2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

419612:SLC2A7
gene id: 419612:SLC2A7
uniprot id: A0A8B8U7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane

419612:CCDC47
gene id: 419612:CCDC47
uniprot id: A0A8B8R4S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC47 family.
messages: Rough endoplasmic reticulum membrane

419612:PCOLCE
gene id: 419612:PCOLCE
uniprot id: A0A8B6YIC3
uniprot id: A0A8B8RES6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

419612:KDM3A
gene id: 419612:KDM3A
uniprot id: A0A8B8S623
uniprot id: A0A8B8S852
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

419612:MPDU1
gene id: 419612:MPDU1
uniprot id: A0A8B6YBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane
messages: Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.

419612:BTG2
gene id: 419612:BTG2
uniprot id: S9XC20
names: Similarity
messages: Belongs to the BTG family.

419612:LOC102514286
gene id: 419612:LOC102514286
uniprot id: S9WE13
names: Similarity
messages: Belongs to the ferritin family.

419612:LOC102523076
gene id: 419612:LOC102523076
uniprot id: A0A8B6YH00
uniprot id: A0A8B7KAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

419612:INSL3
gene id: 419612:INSL3
uniprot id: A0A8B8RT95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted
messages: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.

419612:LOC102505998
gene id: 419612:LOC102505998
uniprot id: A0A8B8U7K6
names: Subcellular Location Annotation
messages: Nucleus

419612:TSPYL4
gene id: 419612:TSPYL4
uniprot id: A0A8B6YPH2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

419612:LOC102507082
gene id: 419612:LOC102507082
uniprot id: A0A8B6YGK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102519101
gene id: 419612:LOC102519101
uniprot id: A0A8B8SKZ4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

419612:VGLL1
gene id: 419612:VGLL1
uniprot id: A0A8B6YPU8
uniprot id: A0A8B8SJS1
uniprot id: A0A8B8SL71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

419612:RIC3
gene id: 419612:RIC3
uniprot id: A0A8B8TRU5
uniprot id: A0A8B8TSQ1
names: Similarity
messages: Belongs to the ric-3 family.

419612:MSI2
gene id: 419612:MSI2
uniprot id: A0A8B8UII4
uniprot id: A0A8B8UII9
uniprot id: A0A8B8UIW8
uniprot id: A0A8B8UIX2
uniprot id: A0A8B8UIY3
uniprot id: A0A8B8UIY8
uniprot id: A0A8B8UJN5
uniprot id: A0A8B8UJN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

419612:HOXA9
gene id: 419612:HOXA9
uniprot id: A0A8B6YBA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

419612:LOC102508626
gene id: 419612:LOC102508626
uniprot id: A0A8B8U2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PTGDS
gene id: 419612:PTGDS
uniprot id: S9XPN1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

419612:CNN3
gene id: 419612:CNN3
uniprot id: A0A8B8TL95
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

419612:TMEM38A
gene id: 419612:TMEM38A
uniprot id: A0A8B6Y726
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

419612:GSK3A
gene id: 419612:GSK3A
uniprot id: A0A8B8THW6
uniprot id: A0A8B8THY9
uniprot id: A0A8B8THZ2
uniprot id: A0A8B8TJ60
uniprot id: A0A8B8TJ64
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

419612:GPNMB
gene id: 419612:GPNMB
uniprot id: A0A8B7K688
names: Similarity
messages: Belongs to the PMEL/NMB family.

419612:ADGRE3
gene id: 419612:ADGRE3
uniprot id: A0A8B8RTP0
uniprot id: A0A8B8RVK4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:TBC1D23
gene id: 419612:TBC1D23
uniprot id: A0A8B6YPU6
uniprot id: A0A8B6YPX6
names: Subcellular Location Annotation
messages: trans-Golgi network

419612:GPR137C
gene id: 419612:GPR137C
uniprot id: A0A8B6YFZ9
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

419612:XPO1
gene id: 419612:XPO1
uniprot id: A0A8B8UG24
uniprot id: A0A8B8UGQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

419612:TNPO2
gene id: 419612:TNPO2
uniprot id: A0A8B8RTZ0
uniprot id: A0A8B8RTZ4
uniprot id: A0A8B8RVJ4
uniprot id: A0A8B8RVU6
names: Subcellular Location Annotation
messages: Cytoplasm

419612:KIFBP
gene id: 419612:KIFBP
uniprot id: A0A8B6YDH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

419612:CMPK2
gene id: 419612:CMPK2
uniprot id: A0A8B8UE47
names: Similarity
messages: Belongs to the thymidylate kinase family.

419612:LOC106728425
gene id: 419612:LOC106728425
uniprot id: A0A8B7KD53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:WNT5A
gene id: 419612:WNT5A
uniprot id: A0A8B8R830
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

419612:RO60
gene id: 419612:RO60
uniprot id: A0A8B8RYZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

419612:FAM53C
gene id: 419612:FAM53C
uniprot id: A0A8B6YFG0
names: Similarity
messages: Belongs to the FAM53 family.

419612:SLC41A2
gene id: 419612:SLC41A2
uniprot id: A0A8B8U4T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

419612:ICAM5
gene id: 419612:ICAM5
uniprot id: A0A8B8RU60
uniprot id: A0A8B8RV98
uniprot id: A0A8B8RVR4
uniprot id: A0A8B8RW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

419612:DOK2
gene id: 419612:DOK2
uniprot id: A0A8B6YCM7
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

419612:TLR1
gene id: 419612:TLR1
uniprot id: A0A8B6YGI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane
messages: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.

419612:HARS2
gene id: 419612:HARS2
uniprot id: A0A8B6Y4U1
uniprot id: A0A8B7K4W4
uniprot id: A0A8B7K789
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

419612:UPK1B
gene id: 419612:UPK1B
uniprot id: A0A8B6YPA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:TSR3
gene id: 419612:TSR3
uniprot id: A0A8B8RDH5
uniprot id: A0A8B8RFE9
uniprot id: A0A8B8RFW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SLC25A5
gene id: 419612:SLC25A5
uniprot id: A0A8B8SPP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

419612:PRPF38A
gene id: 419612:PRPF38A
uniprot id: A0A8B6YBU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

419612:CALCRL
gene id: 419612:CALCRL
uniprot id: A0A8B7KCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

419612:PISD
gene id: 419612:PISD
uniprot id: A0A8B6YFF4
uniprot id: A0A8B7K9W4
uniprot id: A0A8B7KA73
uniprot id: A0A8B8SC45
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

419612:ERG
gene id: 419612:ERG
uniprot id: A0A8B6YN77
uniprot id: A0A8B7KFR1
uniprot id: A0A8B7KGT1
uniprot id: A0A8B8RR91
uniprot id: A0A8B8RSF3
uniprot id: A0A8B8RT63
uniprot id: A0A8B8RTP1
uniprot id: A0A8B8RTT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:LOC102520014
gene id: 419612:LOC102520014
uniprot id: A0A8B8RTJ9
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:MARCHF4
gene id: 419612:MARCHF4
uniprot id: A0A8B6YHE6
names: Subcellular Location Annotation
messages: Membrane

419612:BCLAF3
gene id: 419612:BCLAF3
uniprot id: A0A8B6YNL8
uniprot id: A0A8B8SJ89
uniprot id: A0A8B8SJ93
uniprot id: A0A8B8SKC2
uniprot id: A0A8B8SKM6
uniprot id: A0A8B8SLN1
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

419612:NGDN
gene id: 419612:NGDN
uniprot id: A0A8B6Y4P8
names: Subcellular Location Annotation
messages: nucleolus

419612:FAM135B
gene id: 419612:FAM135B
uniprot id: A0A8B8S1C7
names: Similarity
messages: Belongs to the FAM135 family.

419612:LAMTOR1
gene id: 419612:LAMTOR1
uniprot id: A0A8B6YD06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

419612:C4BPA
gene id: 419612:C4BPA
uniprot id: A0A8B8RYF2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:ZDHHC6
gene id: 419612:ZDHHC6
uniprot id: A0A8B6YFK3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

419612:PPP1CB
gene id: 419612:PPP1CB
uniprot id: A0A8B8UFR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

419612:LOC102510972
gene id: 419612:LOC102510972
uniprot id: A0A8B7K5J7
uniprot id: A0A8B8RUJ6
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC102506853
gene id: 419612:LOC102506853
uniprot id: A0A8B8TA60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:GDI1
gene id: 419612:GDI1
uniprot id: A0A8B8SP05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

419612:SFTPC
gene id: 419612:SFTPC
uniprot id: A0A8B6YBE2
names: Function
names: Subcellular Location Annotation
messages: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
messages: surface film

419612:RPL14
gene id: 419612:RPL14
uniprot id: A0A8B7KEG1
uniprot id: A0A8B8RCV5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

419612:GPAM
gene id: 419612:GPAM
uniprot id: A0A8B6YIE5
uniprot id: A0A8B7K9G2
uniprot id: A0A8B8TX03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

419612:B3GALT5
gene id: 419612:B3GALT5
uniprot id: S9WQ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:KIAA1324L
gene id: 419612:KIAA1324L
uniprot id: A0A8B6YM80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

419612:LOC116665529
gene id: 419612:LOC116665529
uniprot id: S9Y9K0
names: Similarity
messages: Belongs to the ATG8 family.

419612:GON4L
gene id: 419612:GON4L
uniprot id: A0A8B8RRK8
names: Subcellular Location Annotation
messages: Nucleus

419612:IFI30
gene id: 419612:IFI30
uniprot id: A0A8B8RUU6
uniprot id: A0A8B8RV51
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

419612:CDV3
gene id: 419612:CDV3
uniprot id: A0A8B8TPC2
uniprot id: A0A8B8TPC5
uniprot id: A0A8B8TPD0
uniprot id: A0A8B8TPD1
uniprot id: A0A8B8TQ10
uniprot id: A0A8B8TQI0
uniprot id: A0A8B8TQI6
names: Similarity
messages: Belongs to the CDV3 family.

419612:NT5DC4
gene id: 419612:NT5DC4
uniprot id: A0A8B8S5E2
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

419612:LOC116666657
gene id: 419612:LOC116666657
uniprot id: A0A8B8TVP4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SHOX
gene id: 419612:SHOX
uniprot id: A0A8B8SKT3
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC116661680
gene id: 419612:LOC116661680
uniprot id: A0A8B8SIL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:ST6GALNAC5
gene id: 419612:ST6GALNAC5
uniprot id: A0A8B8U892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

419612:VDAC1
gene id: 419612:VDAC1
uniprot id: A0A8B8SR44
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

419612:LOC102505824
gene id: 419612:LOC102505824
uniprot id: A0A8B6YJS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:EGFL8
gene id: 419612:EGFL8
uniprot id: A0A8B6Y9Y3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:NRG2
gene id: 419612:NRG2
uniprot id: A0A8B8SRH4
uniprot id: A0A8B8SSK2
uniprot id: A0A8B8STB5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

419612:RBL1
gene id: 419612:RBL1
uniprot id: A0A8B8RLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

419612:P4HA3
gene id: 419612:P4HA3
uniprot id: A0A8B8TSI0
uniprot id: A0A8B8TTG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

419612:EYA2
gene id: 419612:EYA2
uniprot id: A0A8B7KC64
uniprot id: A0A8B8RIT1
uniprot id: A0A8B8RJ85
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

419612:GLRX
gene id: 419612:GLRX
uniprot id: A0A8B7KG66
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

419612:ACRBP
gene id: 419612:ACRBP
uniprot id: A0A8B8SIW9
names: Subcellular Location Annotation
messages: acrosome

419612:CDC123
gene id: 419612:CDC123
uniprot id: A0A8B6YA24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

419612:ADAM12
gene id: 419612:ADAM12
uniprot id: A0A8B8TW82
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SPOCK3
gene id: 419612:SPOCK3
uniprot id: A0A8B8SAB1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:AZIN1
gene id: 419612:AZIN1
uniprot id: A0A8B8RZN9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

419612:LOC102522519
gene id: 419612:LOC102522519
uniprot id: A0A8B7KF32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:HSPA2
gene id: 419612:HSPA2
uniprot id: S9YQE7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

419612:ERFL
gene id: 419612:ERFL
uniprot id: A0A8B8THW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:DCK
gene id: 419612:DCK
uniprot id: A0A8B8RBF3
names: Similarity
messages: Belongs to the DCK/DGK family.

419612:AP3B2
gene id: 419612:AP3B2
uniprot id: A0A8B8S6D3
uniprot id: A0A8B8S6K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

419612:CDH11
gene id: 419612:CDH11
uniprot id: S9XRE6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

419612:LOC102514899
gene id: 419612:LOC102514899
uniprot id: A0A8B8S299
uniprot id: A0A8B8S3V7
uniprot id: A0A8B8S409
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:GRIN3B
gene id: 419612:GRIN3B
uniprot id: A0A8B8RVR6
uniprot id: A0A8B8RX87
uniprot id: A0A8B8RXJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

419612:RPE65
gene id: 419612:RPE65
uniprot id: A0A8B6YL79
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

419612:WNK4
gene id: 419612:WNK4
uniprot id: A0A8B7K3F5
uniprot id: A0A8B7K3R7
uniprot id: A0A8B8R574
uniprot id: A0A8B8R575
uniprot id: A0A8B8R5E6
uniprot id: A0A8B8R7E6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

419612:CAVIN1
gene id: 419612:CAVIN1
uniprot id: A0A8B8R550
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

419612:LOC102510402
gene id: 419612:LOC102510402
uniprot id: A0A8B6Y5R4
names: Subcellular Location Annotation
messages: Secreted

419612:LAPTM4B
gene id: 419612:LAPTM4B
uniprot id: A0A8B8S1R5
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

419612:ARHGEF7
gene id: 419612:ARHGEF7
uniprot id: A0A8B8UD48
uniprot id: A0A8B8UD50
uniprot id: A0A8B8UD55
uniprot id: A0A8B8UDX5
uniprot id: A0A8B8UDY0
uniprot id: A0A8B8UEH0
names: Subcellular Location Annotation
messages: lamellipodium

419612:PTX4
gene id: 419612:PTX4
uniprot id: A0A8B8RIL7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:CACNA1S
gene id: 419612:CACNA1S
uniprot id: A0A8B8RZ57
uniprot id: A0A8B8RZG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

419612:EFNA3
gene id: 419612:EFNA3
uniprot id: A0A8B8RQ20
uniprot id: A0A8B8RQL0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:KIF22
gene id: 419612:KIF22
uniprot id: A0A8B6YCH4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:LOC102510749
gene id: 419612:LOC102510749
uniprot id: A0A8B8UED3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

419612:ELL3
gene id: 419612:ELL3
uniprot id: A0A8B8T4M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

419612:LOC116663003
gene id: 419612:LOC116663003
uniprot id: A0A8B8SU05
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

419612:LOC102523899
gene id: 419612:LOC102523899
uniprot id: A0A8B8RQ00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TMEM144
gene id: 419612:TMEM144
uniprot id: A0A8B8RWK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

419612:ADAMTS15
gene id: 419612:ADAMTS15
uniprot id: A0A8B7K8B3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:STUM
gene id: 419612:STUM
uniprot id: A0A8B8RX03
uniprot id: A0A8B8RYF0
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102513822
gene id: 419612:LOC102513822
uniprot id: A0A8B6YCK9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

419612:ANAPC2
gene id: 419612:ANAPC2
uniprot id: A0A8B8SXY9
names: Similarity
messages: Belongs to the cullin family.

419612:LOC102517205
gene id: 419612:LOC102517205
uniprot id: S9Y4Q3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

419612:PYY
gene id: 419612:PYY
uniprot id: A0A8B6Y5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

419612:LOC102516613
gene id: 419612:LOC102516613
uniprot id: A0A8B8TYN1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

419612:DYNC1LI1
gene id: 419612:DYNC1LI1
uniprot id: A0A8B8RDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

419612:NPRL3
gene id: 419612:NPRL3
uniprot id: A0A8B6YE30
uniprot id: A0A8B8RF68
uniprot id: A0A8B8RFD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

419612:CDO1
gene id: 419612:CDO1
uniprot id: A0A8B8SQI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

419612:HIKESHI
gene id: 419612:HIKESHI
uniprot id: A0A8B6YJN3
uniprot id: A0A8B8TR48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

419612:SYNE2
gene id: 419612:SYNE2
uniprot id: A0A8B8T721
names: Similarity
messages: Belongs to the nesprin family.

419612:DEFB123
gene id: 419612:DEFB123
uniprot id: A0A8B8RGJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

419612:EEF2K
gene id: 419612:EEF2K
uniprot id: A0A8B8RFP1
uniprot id: A0A8B8RFU8
uniprot id: A0A8B8RHL9
uniprot id: A0A8B8RI46
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

419612:HGD
gene id: 419612:HGD
uniprot id: A0A8B6YKM0
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

419612:SERPINE3
gene id: 419612:SERPINE3
uniprot id: A0A8B8UBY4
names: Similarity
messages: Belongs to the serpin family.

419612:XPO4
gene id: 419612:XPO4
uniprot id: A0A8B8UCN9
uniprot id: A0A8B8UCP4
uniprot id: A0A8B8UDE5
uniprot id: A0A8B8UDH0
uniprot id: A0A8B8UE01
uniprot id: A0A8B8UE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Nucleus

419612:NKIRAS1
gene id: 419612:NKIRAS1
uniprot id: A0A8B8TQD4
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

419612:RSPO2
gene id: 419612:RSPO2
uniprot id: A0A8B6YN71
names: Similarity
messages: Belongs to the R-spondin family.

419612:VPS37D
gene id: 419612:VPS37D
uniprot id: A0A8B8RBU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

419612:USH1G
gene id: 419612:USH1G
uniprot id: A0A8B6Y7W6
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

419612:SPAG7
gene id: 419612:SPAG7
uniprot id: T0MF47
names: Subcellular Location Annotation
messages: Nucleus

419612:GPR180
gene id: 419612:GPR180
uniprot id: A0A8B8UDK8
names: Subcellular Location Annotation
messages: Membrane

419612:APC2
gene id: 419612:APC2
uniprot id: A0A8B8RWT0
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

419612:SLC4A9
gene id: 419612:SLC4A9
uniprot id: A0A8B8SRK6
uniprot id: A0A8B8SRL1
uniprot id: A0A8B8SSA0
uniprot id: A0A8B8SSA5
uniprot id: A0A8B8SSM8
uniprot id: A0A8B8SSN2
uniprot id: A0A8B8STE6
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

419612:HOXC13
gene id: 419612:HOXC13
uniprot id: A0A8B8U3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

419612:PNLIPRP3
gene id: 419612:PNLIPRP3
uniprot id: A0A8B6YEA9
uniprot id: A0A8B8TWP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

419612:CHD6
gene id: 419612:CHD6
uniprot id: A0A8B8RJT1
uniprot id: A0A8B8RK50
uniprot id: A0A8B8RM36
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

419612:PURB
gene id: 419612:PURB
uniprot id: A0A8B8TDB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

419612:ISCA1
gene id: 419612:ISCA1
uniprot id: A0A8B8SUA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

419612:LOC116659135
gene id: 419612:LOC116659135
uniprot id: A0A8B8RWB6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CATSPERE
gene id: 419612:CATSPERE
uniprot id: A0A8B8RWW7
names: Similarity
messages: Belongs to the CATSPERD family.

419612:LOC102522025
gene id: 419612:LOC102522025
uniprot id: S9X9L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MRPL23
gene id: 419612:MRPL23
uniprot id: A0A8B7KCU7
uniprot id: A0A8B8TUS8
uniprot id: A0A8B8TVV7
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

419612:DTNA
gene id: 419612:DTNA
uniprot id: A0A8B8RYS9
uniprot id: A0A8B8RYT3
uniprot id: A0A8B8RYT6
uniprot id: A0A8B8RYU6
uniprot id: A0A8B8S057
uniprot id: A0A8B8S062
uniprot id: A0A8B8S067
uniprot id: A0A8B8S072
uniprot id: A0A8B8S098
uniprot id: A0A8B8S0A3
uniprot id: A0A8B8S0A8
uniprot id: A0A8B8S0B3
uniprot id: A0A8B8S0G2
uniprot id: A0A8B8S0G6
uniprot id: A0A8B8S0H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

419612:MYH10
gene id: 419612:MYH10
uniprot id: A0A8B8UKJ1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

419612:DPP7
gene id: 419612:DPP7
uniprot id: A0A8B8SXU6
uniprot id: A0A8B8SXX9
names: Similarity
messages: Belongs to the peptidase S28 family.

419612:SNCB
gene id: 419612:SNCB
uniprot id: A0A8B8RTE5
names: Similarity
messages: Belongs to the synuclein family.

419612:TTR
gene id: 419612:TTR
uniprot id: A0A8B8S052
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. Interacts with RBP4.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

419612:MTRF1L
gene id: 419612:MTRF1L
uniprot id: A0A8B6YGD6
uniprot id: A0A8B8TH69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

419612:LSM8
gene id: 419612:LSM8
uniprot id: A0A8B6Y904
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

419612:RAB3IL1
gene id: 419612:RAB3IL1
uniprot id: A0A8B8TT56
uniprot id: A0A8B8TT64
uniprot id: A0A8B8TT70
uniprot id: A0A8B8TT71
uniprot id: A0A8B8TU89
uniprot id: A0A8B8TU93
names: Similarity
messages: Belongs to the SEC2 family.

419612:ACHE
gene id: 419612:ACHE
uniprot id: A0A8B8RC38
uniprot id: A0A8B8RC42
uniprot id: A0A8B8RC43
uniprot id: A0A8B8REP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

419612:PM20D2
gene id: 419612:PM20D2
uniprot id: A0A8B8TE08
uniprot id: A0A8B8TE53
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Catalyzes the peptide bond hydrolysis in dipeptides having basic amino acids lysine, ornithine or arginine at C-terminus.

419612:LOC116661905
gene id: 419612:LOC116661905
uniprot id: A0A8B8SK68
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

419612:LOC102517450
gene id: 419612:LOC102517450
uniprot id: A0A8B6YRE4
names: Similarity
messages: Belongs to the pro/parathymosin family.

419612:GET3
gene id: 419612:GET3
uniprot id: A0A8B8RTY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer. Component of a transmembrane domain recognition complex (TRC). Interacts with SERP1 and SEC61B. Interacts with WRB.
messages: nucleolus

419612:RIC8A
gene id: 419612:RIC8A
uniprot id: A0A8B8TWU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

419612:LOC102521229
gene id: 419612:LOC102521229
uniprot id: A0A8B6YPP8
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102504116
gene id: 419612:LOC102504116
uniprot id: A0A8B8RXE4
uniprot id: A0A8B8RYR0
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

419612:FXYD3
gene id: 419612:FXYD3
uniprot id: A0A8B7KA01
uniprot id: A0A8B8TP61
uniprot id: A0A8B8TQC3
names: Similarity
messages: Belongs to the FXYD family.

419612:SDHAF2
gene id: 419612:SDHAF2
uniprot id: A0A8B6Y623
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

419612:MFSD3
gene id: 419612:MFSD3
uniprot id: A0A8B7KB38
uniprot id: A0A8B7KCU9
uniprot id: A0A8B8S2A1
uniprot id: A0A8B8S2J5
uniprot id: S9WX52
names: Subcellular Location Annotation
messages: Membrane

419612:MAP7D1
gene id: 419612:MAP7D1
uniprot id: A0A8B8UB45
uniprot id: A0A8B8UB50
uniprot id: A0A8B8UB51
uniprot id: A0A8B8UB55
uniprot id: A0A8B8UB60
uniprot id: A0A8B8UB63
uniprot id: A0A8B8UBV7
uniprot id: A0A8B8UBW1
uniprot id: A0A8B8UBW7
uniprot id: A0A8B8UBX1
uniprot id: A0A8B8UBX6
uniprot id: A0A8B8UC11
uniprot id: A0A8B8UC16
uniprot id: A0A8B8UC20
uniprot id: A0A8B8UC24
uniprot id: A0A8B8UCG2
uniprot id: A0A8B8UCG6
uniprot id: A0A8B8UCH2
uniprot id: A0A8B8UCH7
names: Similarity
messages: Belongs to the MAP7 family.

419612:SF3B6
gene id: 419612:SF3B6
uniprot id: A0A8B6YMM6
names: Subcellular Location Annotation
messages: Nucleus

419612:TMEM178B
gene id: 419612:TMEM178B
uniprot id: A0A8B6YJY6
uniprot id: A0A8B8TC30
names: Similarity
messages: Belongs to the TMEM178 family.

419612:ARRDC1
gene id: 419612:ARRDC1
uniprot id: A0A8B8SY49
uniprot id: A0A8B8SYK9
uniprot id: A0A8B8SZA4
names: Similarity
messages: Belongs to the arrestin family.

419612:SLC25A38
gene id: 419612:SLC25A38
uniprot id: A0A8B8RAR1
uniprot id: S9W5E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane
messages: Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis.

419612:CCDC25
gene id: 419612:CCDC25
uniprot id: A0A8B6YNP8
uniprot id: A0A8B8SA28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

419612:NEU3
gene id: 419612:NEU3
uniprot id: A0A8B8TSL8
uniprot id: S9YQ30
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

419612:MMP9
gene id: 419612:MMP9
uniprot id: A0A8B6YLZ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with LCN2. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1.
messages: extracellular matrix

419612:LOC102513146
gene id: 419612:LOC102513146
uniprot id: A0A8B6YA86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

419612:IL21
gene id: 419612:IL21
uniprot id: A0A8B6YBR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

419612:TUBB2A
gene id: 419612:TUBB2A
uniprot id: A0A8B8RMB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

419612:NCOR1
gene id: 419612:NCOR1
uniprot id: A0A8B8UJP3
uniprot id: A0A8B8UJQ0
uniprot id: A0A8B8UJQ6
uniprot id: A0A8B8UJY3
uniprot id: A0A8B8UJZ0
uniprot id: A0A8B8UJZ7
uniprot id: A0A8B8UK21
uniprot id: A0A8B8UK26
uniprot id: A0A8B8UK31
uniprot id: A0A8B8UK39
uniprot id: A0A8B8UK59
uniprot id: A0A8B8UK65
uniprot id: A0A8B8UK70
uniprot id: A0A8B8UKU0
uniprot id: A0A8B8UKU3
uniprot id: A0A8B8UKU8
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

419612:ILK
gene id: 419612:ILK
uniprot id: A0A8B8TRZ7
uniprot id: S9Y919
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

419612:LOC102522094
gene id: 419612:LOC102522094
uniprot id: S9WC04
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

419612:RPS6KA6
gene id: 419612:RPS6KA6
uniprot id: A0A8B8SKA3
uniprot id: A0A8B8SKA8
uniprot id: A0A8B8SKB0
uniprot id: A0A8B8SLD5
uniprot id: A0A8B8SLE2
uniprot id: A0A8B8SLQ4
uniprot id: A0A8B8SML5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

419612:TMEM63B
gene id: 419612:TMEM63B
uniprot id: A0A8B8RM97
uniprot id: A0A8B8RPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

419612:ELN
gene id: 419612:ELN
uniprot id: A0A8B7K7G3
uniprot id: A0A8B7K7S4
uniprot id: A0A8B7K7Y5
uniprot id: A0A8B7K9L2
uniprot id: A0A8B8RBR6
uniprot id: A0A8B8RBR7
uniprot id: A0A8B8RBR8
uniprot id: A0A8B8RDV6
uniprot id: A0A8B8RED0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elastin family.
messages: Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle.
messages: extracellular matrix

419612:WNT8A
gene id: 419612:WNT8A
uniprot id: A0A8B8S4R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

419612:AMZ2
gene id: 419612:AMZ2
uniprot id: A0A8B8R4P6
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

419612:MS4A13
gene id: 419612:MS4A13
uniprot id: A0A8B8TWZ9
names: Similarity
messages: Belongs to the MS4A family.

419612:LOC102521223
gene id: 419612:LOC102521223
uniprot id: A0A8B6YNW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SLC5A7
gene id: 419612:SLC5A7
uniprot id: A0A8B8U5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

419612:XYLB
gene id: 419612:XYLB
uniprot id: A0A8B8RAS7
uniprot id: A0A8B8RAT9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

419612:CEL
gene id: 419612:CEL
uniprot id: A0A8B8SXS8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

419612:ABCG1
gene id: 419612:ABCG1
uniprot id: A0A8B8REW9
uniprot id: A0A8B8RF54
uniprot id: A0A8B8RH68
uniprot id: A0A8B8RHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

419612:IL20
gene id: 419612:IL20
uniprot id: A0A8B6YEH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

419612:SSU72
gene id: 419612:SSU72
uniprot id: A0A8B8U993
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

419612:ZSCAN30
gene id: 419612:ZSCAN30
uniprot id: A0A8B8RYU8
names: Subcellular Location Annotation
messages: Nucleus

419612:CCNO
gene id: 419612:CCNO
uniprot id: A0A8B6YGH4
uniprot id: A0A8B8SD64
names: Similarity
messages: Belongs to the cyclin family.

419612:SLC8A2
gene id: 419612:SLC8A2
uniprot id: A0A8B8TH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

419612:CLCN6
gene id: 419612:CLCN6
uniprot id: A0A8B7KH47
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:TMC3
gene id: 419612:TMC3
uniprot id: A0A8B8S5X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

419612:TMEM218
gene id: 419612:TMEM218
uniprot id: S9YMV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

419612:SLC7A3
gene id: 419612:SLC7A3
uniprot id: A0A8B6YK53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

419612:PRKAR1B
gene id: 419612:PRKAR1B
uniprot id: A0A8B8RCM2
uniprot id: A0A8B8RCP4
uniprot id: A0A8B8REM9
uniprot id: A0A8B8RF51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

419612:OTULINL
gene id: 419612:OTULINL
uniprot id: A0A8B8S773
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

419612:LOC102515248
gene id: 419612:LOC102515248
uniprot id: A0A8B8RBW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

419612:BASP1
gene id: 419612:BASP1
uniprot id: A0A8B8S8X7
names: Similarity
messages: Belongs to the BASP1 family.

419612:ARID1A
gene id: 419612:ARID1A
uniprot id: A0A8B8UAY0
uniprot id: A0A8B8UB34
names: Subcellular Location Annotation
messages: Nucleus

419612:FAM120B
gene id: 419612:FAM120B
uniprot id: A0A8B8TGC8
uniprot id: A0A8B8TGE0
uniprot id: A0A8B8THQ1
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

419612:S100A2
gene id: 419612:S100A2
uniprot id: A0A8B6Y923
uniprot id: A0A8B8RSB0
names: Similarity
messages: Belongs to the S-100 family.

419612:TMEM167A
gene id: 419612:TMEM167A
uniprot id: A0A8B7K5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

419612:GABRR1
gene id: 419612:GABRR1
uniprot id: A0A8B6YB78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:CDC6
gene id: 419612:CDC6
uniprot id: A0A8B8R7A1
uniprot id: A0A8B8R7A2
uniprot id: A0A8B8R7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
messages: Nucleus

419612:MORF4L1
gene id: 419612:MORF4L1
uniprot id: A0A8B8S458
uniprot id: A0A8B8S5P5
names: Subcellular Location Annotation
messages: Nucleus

419612:PXMP2
gene id: 419612:PXMP2
uniprot id: A0A8B6YAU2
uniprot id: A0A8B8SC91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

419612:RBM15B
gene id: 419612:RBM15B
uniprot id: A0A8B6Y6D5
names: Similarity
messages: Belongs to the RRM Spen family.

419612:LOC102513491
gene id: 419612:LOC102513491
uniprot id: A0A8B6YFL9
uniprot id: A0A8B7K7G2
uniprot id: A0A8B8RLN5
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

419612:ST7L
gene id: 419612:ST7L
uniprot id: A0A8B8TM87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

419612:PSMA6
gene id: 419612:PSMA6
uniprot id: A0A8B6YKY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

419612:ILVBL
gene id: 419612:ILVBL
uniprot id: A0A8B8RTN0
names: Similarity
messages: Belongs to the TPP enzyme family.

419612:IGF2BP1
gene id: 419612:IGF2BP1
uniprot id: A0A8B8R703
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: P-body
messages: Stress granule
messages: filopodium
messages: growth cone
messages: lamellipodium
messages: perinuclear region

419612:ASB17
gene id: 419612:ASB17
uniprot id: A0A8B6YRQ5
names: Function
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

419612:CYSLTR2
gene id: 419612:CYSLTR2
uniprot id: S9WZS1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:LOC102516274
gene id: 419612:LOC102516274
uniprot id: A0A8B6YPS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MLLT11
gene id: 419612:MLLT11
uniprot id: A0A8B6YL60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

419612:MS4A4A
gene id: 419612:MS4A4A
uniprot id: A0A8B8TSY8
uniprot id: A0A8B8TU06
names: Similarity
messages: Belongs to the MS4A family.

419612:THADA
gene id: 419612:THADA
uniprot id: A0A8B7KBA3
uniprot id: A0A8B8UFC1
uniprot id: A0A8B8UGS2
names: Function
names: Similarity
messages: Belongs to the THADA family.
messages: Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.

419612:RAB3GAP1
gene id: 419612:RAB3GAP1
uniprot id: A0A8B6YLB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm
messages: Endoplasmic reticulum

419612:LOC102507932
gene id: 419612:LOC102507932
uniprot id: A0A8B8RRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

419612:PPIE
gene id: 419612:PPIE
uniprot id: A0A8B6YIE6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

419612:HOXB2
gene id: 419612:HOXB2
uniprot id: A0A8B8R716
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102524617
gene id: 419612:LOC102524617
uniprot id: A0A8B7KBF5
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

419612:ITIH4
gene id: 419612:ITIH4
uniprot id: A0A8B8R889
uniprot id: A0A8B8R893
uniprot id: A0A8B8R8D7
uniprot id: A0A8B8RAD0
uniprot id: A0A8B8RAD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

419612:CRPPA
gene id: 419612:CRPPA
uniprot id: A0A8B8TC39
uniprot id: A0A8B8TCC3
uniprot id: A0A8B8TDB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

419612:SLC39A11
gene id: 419612:SLC39A11
uniprot id: A0A8B8R4A0
uniprot id: A0A8B8R4A8
uniprot id: A0A8B8R4B2
uniprot id: A0A8B8R4B7
uniprot id: A0A8B8R4H7
uniprot id: A0A8B8R4I4
uniprot id: A0A8B8R6I4
uniprot id: A0A8B8R6J0
names: Subcellular Location Annotation
messages: Membrane

419612:PDE10A
gene id: 419612:PDE10A
uniprot id: A0A8B8TG51
uniprot id: A0A8B8TG52
uniprot id: A0A8B8TG56
uniprot id: A0A8B8TG57
uniprot id: A0A8B8TG58
uniprot id: A0A8B8TG63
uniprot id: A0A8B8TG93
uniprot id: A0A8B8TG98
uniprot id: A0A8B8THI4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

419612:TULP1
gene id: 419612:TULP1
uniprot id: A0A8B8RN99
names: Similarity
messages: Belongs to the TUB family.

419612:IRF8
gene id: 419612:IRF8
uniprot id: A0A8B8RT15
names: Subcellular Location Annotation
messages: Nucleus

419612:THBS2
gene id: 419612:THBS2
uniprot id: A0A8B8TGA8
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:GPR108
gene id: 419612:GPR108
uniprot id: A0A8B7K5H1
names: Subcellular Location Annotation
messages: Membrane

419612:NHEJ1
gene id: 419612:NHEJ1
uniprot id: A0A8B7KBD2
uniprot id: A0A8B7KBN5
uniprot id: A0A8B7KC99
uniprot id: A0A8B7KDF2
uniprot id: A0A8B8T206
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

419612:ANKRD13C
gene id: 419612:ANKRD13C
uniprot id: A0A8B6YMI6
uniprot id: A0A8B8U794
uniprot id: A0A8B8U8A6
names: Subcellular Location Annotation
messages: Membrane

419612:PTOV1
gene id: 419612:PTOV1
uniprot id: A0A8B8TGL8
uniprot id: A0A8B8TGQ0
uniprot id: A0A8B8THY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activates transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.
messages: Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: May interact with CREBBP. Interacts with FLOT1.
messages: Nucleus
messages: perinuclear region

419612:RBM47
gene id: 419612:RBM47
uniprot id: A0A8B8UCQ2
uniprot id: A0A8B8UDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Cytoplasm
messages: Nucleus

419612:COG4
gene id: 419612:COG4
uniprot id: A0A8B8TLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

419612:ADAMTS6
gene id: 419612:ADAMTS6
uniprot id: A0A8B8SGN9
uniprot id: A0A8B8SI64
uniprot id: A0A8B8SI67
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:CCDC85A
gene id: 419612:CCDC85A
uniprot id: A0A8B6YPZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

419612:MRPL49
gene id: 419612:MRPL49
uniprot id: T0NJL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

419612:LOC102513911
gene id: 419612:LOC102513911
uniprot id: A0A8B6YHY1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

419612:NCBP1
gene id: 419612:NCBP1
uniprot id: A0A8B8SVD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

419612:CSNK2A2
gene id: 419612:CSNK2A2
uniprot id: A0A8B6YC84
uniprot id: A0A8B8TJC1
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:GPC3
gene id: 419612:GPC3
uniprot id: A0A8B8SJI7
uniprot id: A0A8B8SLX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

419612:ATG2B
gene id: 419612:ATG2B
uniprot id: A0A8B6YIW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

419612:PARP12
gene id: 419612:PARP12
uniprot id: A0A8B8TAV3
uniprot id: A0A8B8TAZ6
names: Similarity
messages: Belongs to the ARTD/PARP family.

419612:RNF121
gene id: 419612:RNF121
uniprot id: A0A8B6YGM8
uniprot id: A0A8B8TSA7
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102506275
gene id: 419612:LOC102506275
uniprot id: S9XDG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FAIM2
gene id: 419612:FAIM2
uniprot id: A0A8B6YAD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

419612:OPN1SW
gene id: 419612:OPN1SW
uniprot id: S9Y0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Photoreceptor inner segment
messages: photoreceptor outer segment

419612:GABRA5
gene id: 419612:GABRA5
uniprot id: A0A8B8S3S9
uniprot id: A0A8B8S538
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:NUP62
gene id: 419612:NUP62
uniprot id: A0A8B6Y6G7
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

419612:PROM2
gene id: 419612:PROM2
uniprot id: A0A8B8S5C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

419612:LOC102512965
gene id: 419612:LOC102512965
uniprot id: A0A8B8SGG9
names: Similarity
messages: Belongs to the ATG8 family.

419612:LOC102519078
gene id: 419612:LOC102519078
uniprot id: A0A8B7K8V2
uniprot id: A0A8B8TYA3
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:GPX4
gene id: 419612:GPX4
uniprot id: A0A8B8RX78
uniprot id: A0A8B8RXI6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

419612:HMBOX1
gene id: 419612:HMBOX1
uniprot id: A0A8B6YCM6
uniprot id: A0A8B6YG97
uniprot id: A0A8B7K7J9
uniprot id: A0A8B7K7M2
uniprot id: A0A8B7K7Y2
uniprot id: A0A8B7K847
uniprot id: A0A8B8S9D0
uniprot id: A0A8B8S9D5
uniprot id: A0A8B8S9D7
uniprot id: A0A8B8S9E2
uniprot id: A0A8B8SAL6
uniprot id: A0A8B8SAS0
uniprot id: A0A8B8SBQ0
uniprot id: A0A8B8SBQ7
names: Subcellular Location Annotation
messages: Nucleus

419612:FUT4
gene id: 419612:FUT4
uniprot id: A0A8B8TPM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

419612:C28H2orf68
gene id: 419612:C28H2orf68
uniprot id: A0A8B8S5A0
names: Similarity
messages: Belongs to the UPF0561 family.

419612:DHRS9
gene id: 419612:DHRS9
uniprot id: S9WVW0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:GLRA1
gene id: 419612:GLRA1
uniprot id: A0A8B6Y761
uniprot id: A0A8B6YAF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

419612:TUBGCP6
gene id: 419612:TUBGCP6
uniprot id: A0A8B8U1K8
uniprot id: A0A8B8U2L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

419612:INTS10
gene id: 419612:INTS10
uniprot id: A0A8B8S1Y5
uniprot id: A0A8B8S3A1
uniprot id: A0A8B8S3A6
uniprot id: A0A8B8S3J4
uniprot id: A0A8B8S3J9
uniprot id: A0A8B8S3N6
uniprot id: A0A8B8S3P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

419612:A3GALT2
gene id: 419612:A3GALT2
uniprot id: A0A8B8UAY4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

419612:SRC
gene id: 419612:SRC
uniprot id: A0A8B8RLH6
uniprot id: A0A8B8RLZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

419612:KPNA3
gene id: 419612:KPNA3
uniprot id: A0A8B8UBV2
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

419612:HBS1L
gene id: 419612:HBS1L
uniprot id: A0A8B6YJ11
uniprot id: A0A8B6YMM9
uniprot id: A0A8B7KDJ9
names: Subcellular Location Annotation
messages: Cytoplasm

419612:ACSS2
gene id: 419612:ACSS2
uniprot id: A0A8B8RL61
uniprot id: A0A8B8RLM1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

419612:SLC23A1
gene id: 419612:SLC23A1
uniprot id: A0A8B7K7C9
uniprot id: A0A8B7K7I2
uniprot id: A0A8B8SRG4
uniprot id: A0A8B8SRG5
uniprot id: A0A8B8STA7
names: Subcellular Location Annotation
messages: Membrane

419612:TMEM121
gene id: 419612:TMEM121
uniprot id: A0A8B8T941
uniprot id: A0A8B8T9K8
names: Similarity
messages: Belongs to the TMEM121 family.

419612:CCT8L2
gene id: 419612:CCT8L2
uniprot id: A0A8B8T9T3
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

419612:GDF2
gene id: 419612:GDF2
uniprot id: A0A8B6YNL0
names: Similarity
messages: Belongs to the TGF-beta family.

419612:ADIPOR2
gene id: 419612:ADIPOR2
uniprot id: A0A8B8SGL8
uniprot id: A0A8B8SJ62
uniprot id: A0A8B8SJ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

419612:RPS11
gene id: 419612:RPS11
uniprot id: A0A8B6Y7C2
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

419612:CD244
gene id: 419612:CD244
uniprot id: A0A8B7KED0
names: Subcellular Location Annotation
messages: Membrane

419612:PCYT2
gene id: 419612:PCYT2
uniprot id: A0A8B8R314
names: Similarity
messages: Belongs to the cytidylyltransferase family.

419612:UBE2U
gene id: 419612:UBE2U
uniprot id: A0A8B8U7V8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:LOC102524330
gene id: 419612:LOC102524330
uniprot id: A0A8B7K7L3
names: Subcellular Location Annotation
messages: Cytoplasm

419612:DUSP4
gene id: 419612:DUSP4
uniprot id: A0A8B8S4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

419612:LOC102523196
gene id: 419612:LOC102523196
uniprot id: A0A8B8RZ12
names: Subcellular Location Annotation
messages: Cytoplasm

419612:LOC102510660
gene id: 419612:LOC102510660
uniprot id: S9W8W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

419612:TMEM80
gene id: 419612:TMEM80
uniprot id: A0A8B8TV87
uniprot id: A0A8B8TV95
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102520409
gene id: 419612:LOC102520409
uniprot id: S9YG78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

419612:IARS2
gene id: 419612:IARS2
uniprot id: A0A8B8RYT7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

419612:NEUROD2
gene id: 419612:NEUROD2
uniprot id: A0A8B8UJ30
names: Subcellular Location Annotation
messages: Nucleus

419612:F9
gene id: 419612:F9
uniprot id: A0A8B6YSJ1
uniprot id: A0A8B8SPB4
uniprot id: A0A8B8SRE9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

419612:DICER1
gene id: 419612:DICER1
uniprot id: A0A8B8T8R2
uniprot id: A0A8B8T8R7
uniprot id: A0A8B8T990
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

419612:BDH1
gene id: 419612:BDH1
uniprot id: A0A8B7K630
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:LOC102523539
gene id: 419612:LOC102523539
uniprot id: A0A8B8RPL0
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:KIAA1324
gene id: 419612:KIAA1324
uniprot id: A0A8B6YB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

419612:TP53BP2
gene id: 419612:TP53BP2
uniprot id: A0A8B8RX38
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102517821
gene id: 419612:LOC102517821
uniprot id: A0A8B7KG64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:NSDHL
gene id: 419612:NSDHL
uniprot id: A0A8B6YIN7
names: Similarity
messages: Belongs to the 3-beta-HSD family.

419612:NEURL2
gene id: 419612:NEURL2
uniprot id: A0A8B6YJC1
uniprot id: A0A8B8RIQ1
names: Subcellular Location Annotation
messages: Cytoplasm

419612:PPARA
gene id: 419612:PPARA
uniprot id: A0A8B8U2J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
messages: Nucleus

419612:SYPL2
gene id: 419612:SYPL2
uniprot id: A0A8B8TM11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

419612:FXYD4
gene id: 419612:FXYD4
uniprot id: A0A8B7KF75
uniprot id: A0A8B8TZC0
uniprot id: A0A8B8U0C1
names: Similarity
messages: Belongs to the FXYD family.

419612:HYAL3
gene id: 419612:HYAL3
uniprot id: A0A8B6Y5V4
uniprot id: A0A8B6Y6E5
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

419612:KIAA1191
gene id: 419612:KIAA1191
uniprot id: A0A8B6YE94
uniprot id: A0A8B7K9F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P33MONOX family.
messages: Cytoplasm
messages: Interacts with NELFB, NOL12 and PRNP.
messages: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

419612:PDHA2
gene id: 419612:PDHA2
uniprot id: S9WRU4
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

419612:LOC102519131
gene id: 419612:LOC102519131
uniprot id: A0A8B7K8F3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102514893
gene id: 419612:LOC102514893
uniprot id: A0A8B6YFS1
uniprot id: A0A8B7K7K0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

419612:GALNT17
gene id: 419612:GALNT17
uniprot id: A0A8B6YJU4
uniprot id: A0A8B8RG29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

419612:AHCYL2
gene id: 419612:AHCYL2
uniprot id: A0A8B8TEN3
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

419612:LOC116661422
gene id: 419612:LOC116661422
uniprot id: A0A8B8SI02
names: Subcellular Location Annotation
messages: Cytoplasm

419612:TMEM159
gene id: 419612:TMEM159
uniprot id: A0A8B8RFR2
uniprot id: S9YGG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

419612:LOC102520515
gene id: 419612:LOC102520515
uniprot id: S9YE81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PCNA
gene id: 419612:PCNA
uniprot id: S9WSK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

419612:GRK5
gene id: 419612:GRK5
uniprot id: A0A8B8TWK1
uniprot id: A0A8B8TWK2
uniprot id: A0A8B8TWK7
uniprot id: A0A8B8TXM2
uniprot id: A0A8B8TXY3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

419612:ZNF408
gene id: 419612:ZNF408
uniprot id: A0A8B8TQB4
names: Subcellular Location Annotation
messages: Nucleus

419612:ANG
gene id: 419612:ANG
uniprot id: A0A8B8T5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

419612:EGR3
gene id: 419612:EGR3
uniprot id: A0A8B8S9B4
uniprot id: A0A8B8SBM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

419612:MTFR1
gene id: 419612:MTFR1
uniprot id: A0A8B8S6T0
uniprot id: A0A8B8S842
uniprot id: A0A8B8S8Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

419612:TESMIN
gene id: 419612:TESMIN
uniprot id: A0A8B8TVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

419612:EPDR1
gene id: 419612:EPDR1
uniprot id: A0A8B8TD28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ependymin family.
messages: Binds anionic lipids and gangliosides at acidic pH.
messages: Lysosome lumen

419612:EEF1AKMT2
gene id: 419612:EEF1AKMT2
uniprot id: A0A8B6YJ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

419612:ATP13A3
gene id: 419612:ATP13A3
uniprot id: A0A8B8T6S7
uniprot id: A0A8B8T6T1
uniprot id: A0A8B8T6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

419612:RHPN2
gene id: 419612:RHPN2
uniprot id: A0A8B8TIT2
names: Similarity
messages: Belongs to the RHPN family.

419612:FAM72A
gene id: 419612:FAM72A
uniprot id: A0A8B6YEF8
uniprot id: A0A8B8RYA8
uniprot id: A0A8B8RZQ1
uniprot id: A0A8B8RZR3
names: Similarity
messages: Belongs to the FAM72 family.

419612:RBBP8
gene id: 419612:RBBP8
uniprot id: A0A8B7KCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

419612:CCNJL
gene id: 419612:CCNJL
uniprot id: A0A8B8SSJ8
names: Similarity
messages: Belongs to the cyclin family.

419612:HSPA9
gene id: 419612:HSPA9
uniprot id: A0A8B8ST97
names: Similarity
messages: Belongs to the heat shock protein 70 family.

419612:GPSM1
gene id: 419612:GPSM1
uniprot id: A0A8B8SXX4
names: Similarity
messages: Belongs to the GPSM family.

419612:POMGNT2
gene id: 419612:POMGNT2
uniprot id: S9X7V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:APH1A
gene id: 419612:APH1A
uniprot id: A0A8B6YH60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

419612:ERO1B
gene id: 419612:ERO1B
uniprot id: A0A8B8TZQ8
uniprot id: A0A8B8TZX7
uniprot id: A0A8B8U110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

419612:BLOC1S1
gene id: 419612:BLOC1S1
uniprot id: A0A8B6YB13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Lysosome membrane
messages: May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5F1A and NDUFA9.
messages: Mitochondrion intermembrane space

419612:C7H7orf25
gene id: 419612:C7H7orf25
uniprot id: A0A8B6YLZ1
names: Similarity
messages: Belongs to the UPF0415 family.

419612:LOC102516014
gene id: 419612:LOC102516014
uniprot id: A0A8B6YRD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:IDNK
gene id: 419612:IDNK
uniprot id: A0A8B8STG9
uniprot id: A0A8B8STZ4
uniprot id: A0A8B8SUE1
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

419612:LOC102509395
gene id: 419612:LOC102509395
uniprot id: A0A8B8R7G8
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

419612:DDX27
gene id: 419612:DDX27
uniprot id: A0A8B6Y7J2
names: Similarity
messages: Belongs to the DEAD box helicase family.

419612:CACNA1A
gene id: 419612:CACNA1A
uniprot id: A0A8B8RTU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents.

419612:ADTRP
gene id: 419612:ADTRP
uniprot id: A0A8B8RKC1
uniprot id: A0A8B8RKC3
uniprot id: A0A8B8RKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

419612:EBAG9
gene id: 419612:EBAG9
uniprot id: A0A8B7KBU7
uniprot id: A0A8B8S1E7
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

419612:BUD31
gene id: 419612:BUD31
uniprot id: A0A8B8RCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

419612:GRM3
gene id: 419612:GRM3
uniprot id: A0A8B6YM39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

419612:TAF1D
gene id: 419612:TAF1D
uniprot id: A0A8B7KB19
uniprot id: A0A8B7KB36
uniprot id: A0A8B8TPN0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts with UBTF.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

419612:SKAP1
gene id: 419612:SKAP1
uniprot id: A0A8B8R726
names: Similarity
messages: Belongs to the SKAP family.

419612:LOC102520714
gene id: 419612:LOC102520714
uniprot id: S9XDF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

419612:SETDB1
gene id: 419612:SETDB1
uniprot id: A0A8B7KD76
uniprot id: A0A8B8RQI8
uniprot id: A0A8B8RQJ8
uniprot id: A0A8B8RS93
uniprot id: A0A8B8RSK0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

419612:LOC102513955
gene id: 419612:LOC102513955
uniprot id: A0A8B8SL10
names: Similarity
messages: Belongs to the tumor necrosis factor family.

419612:LOC102510364
gene id: 419612:LOC102510364
uniprot id: A0A8B8RRP4
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

419612:IRAK1BP1
gene id: 419612:IRAK1BP1
uniprot id: A0A8B6YE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

419612:RBFOX2
gene id: 419612:RBFOX2
uniprot id: A0A8B6YEY3
uniprot id: A0A8B7K999
uniprot id: A0A8B7KBC8
uniprot id: A0A8B8U0A8
uniprot id: A0A8B8U0B3
uniprot id: A0A8B8U0B7
uniprot id: A0A8B8U0C0
uniprot id: A0A8B8U0C5
uniprot id: A0A8B8U0L8
uniprot id: A0A8B8U0M3
uniprot id: A0A8B8U0M8
uniprot id: A0A8B8U0N4
uniprot id: A0A8B8U1C4
uniprot id: A0A8B8U1C9
uniprot id: A0A8B8U1D4
uniprot id: A0A8B8U1D8
uniprot id: A0A8B8U1L7
uniprot id: A0A8B8U1M1
uniprot id: A0A8B8U1M5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

419612:HIGD1B
gene id: 419612:HIGD1B
uniprot id: A0A8B6Y5M4
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

419612:RPS6KA2
gene id: 419612:RPS6KA2
uniprot id: A0A8B8THI8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

419612:BMP3
gene id: 419612:BMP3
uniprot id: A0A8B8R486
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

419612:SLA
gene id: 419612:SLA
uniprot id: A0A8B7KD64
uniprot id: A0A8B8S039
names: Subcellular Location Annotation
messages: Cytoplasm

419612:LOC116661556
gene id: 419612:LOC116661556
uniprot id: A0A8B8SHQ7
uniprot id: A0A8B8SHR4
uniprot id: A0A8B8SIT9
uniprot id: A0A8B8SJ07
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MPDZ
gene id: 419612:MPDZ
uniprot id: A0A8B8SVI8
names: Subcellular Location Annotation
messages: Cell membrane
messages: tight junction

419612:UXT
gene id: 419612:UXT
uniprot id: A0A8B6YLN7
names: Similarity
messages: Belongs to the UXT family.

419612:FAM228A
gene id: 419612:FAM228A
uniprot id: A0A8B8UHJ5
names: Similarity
messages: Belongs to the FAM228 family.

419612:NDUFB7
gene id: 419612:NDUFB7
uniprot id: S9XNL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

419612:LACC1
gene id: 419612:LACC1
uniprot id: A0A8B8UBL0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

419612:GTF2F2
gene id: 419612:GTF2F2
uniprot id: A0A8B6Y812
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

419612:FAT1
gene id: 419612:FAT1
uniprot id: A0A8B8S2V6
uniprot id: A0A8B8S4P4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:VIP
gene id: 419612:VIP
uniprot id: A0A8B6YG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

419612:SEM1
gene id: 419612:SEM1
uniprot id: A0A8B6Y9Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

419612:OVCH2
gene id: 419612:OVCH2
uniprot id: A0A8B8TRV2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:RAB38
gene id: 419612:RAB38
uniprot id: A0A8B7KEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

419612:GPI
gene id: 419612:GPI
uniprot id: A0A8B8TIJ8
names: Similarity
messages: Belongs to the GPI family.

419612:KCNA2
gene id: 419612:KCNA2
uniprot id: S9W5C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: lamellipodium membrane
messages: paranodal septate junction
messages: synaptosome

419612:WSCD2
gene id: 419612:WSCD2
uniprot id: A0A8B7K4K1
uniprot id: A0A8B8SBN8
names: Function
names: Similarity
messages: Belongs to the WSCD family.
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

419612:LOC102513045
gene id: 419612:LOC102513045
uniprot id: S9XIA7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

419612:LOC102513320
gene id: 419612:LOC102513320
uniprot id: S9W7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:STARD13
gene id: 419612:STARD13
uniprot id: A0A8B8UDL0
names: Subcellular Location Annotation
messages: Cytoplasm

419612:S1PR3
gene id: 419612:S1PR3
uniprot id: A0A8B8S9V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:GNG10
gene id: 419612:GNG10
uniprot id: A0A8B8SW76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

419612:CEBPE
gene id: 419612:CEBPE
uniprot id: S9YJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

419612:LOC102503636
gene id: 419612:LOC102503636
uniprot id: A0A8B6Y8I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102508145
gene id: 419612:LOC102508145
uniprot id: A0A8B8RXK2
uniprot id: A0A8B8RYZ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102508668
gene id: 419612:LOC102508668
uniprot id: A0A8B6YAP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:GCAT
gene id: 419612:GCAT
uniprot id: A0A8B6Y764
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

419612:STK39
gene id: 419612:STK39
uniprot id: A0A8B8SZR3
uniprot id: A0A8B8SZR4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

419612:LOC106728935
gene id: 419612:LOC106728935
uniprot id: A0A8B7K6I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:B3GAT2
gene id: 419612:B3GAT2
uniprot id: A0A8B8TDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:LOC102513394
gene id: 419612:LOC102513394
uniprot id: A0A8B7K554
names: Similarity
messages: Belongs to the threonine aldolase family.

419612:SLC20A1
gene id: 419612:SLC20A1
uniprot id: A0A8B8S635
uniprot id: A0A8B8S857
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

419612:DNAL4
gene id: 419612:DNAL4
uniprot id: A0A8B8U208
uniprot id: T0MFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

419612:NKX2-3
gene id: 419612:NKX2-3
uniprot id: A0A8B8TXH9
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102511307
gene id: 419612:LOC102511307
uniprot id: A0A8B8U3J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

419612:DYNC2H1
gene id: 419612:DYNC2H1
uniprot id: A0A8B6YGS5
names: Similarity
messages: Belongs to the dynein heavy chain family.

419612:AGPAT1
gene id: 419612:AGPAT1
uniprot id: A0A8B7K622
uniprot id: A0A8B8RL26
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

419612:CAPN9
gene id: 419612:CAPN9
uniprot id: A0A8B8TZI9
uniprot id: A0A8B8U0U3
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:PROK2
gene id: 419612:PROK2
uniprot id: A0A8B8R7M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

419612:LOC102522435
gene id: 419612:LOC102522435
uniprot id: A0A8B8TRG5
names: Similarity
messages: Belongs to the calcitonin family.

419612:LOC102521362
gene id: 419612:LOC102521362
uniprot id: A0A8B7KEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

419612:TWISTNB
gene id: 419612:TWISTNB
uniprot id: A0A8B8TCA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

419612:LOC102523643
gene id: 419612:LOC102523643
uniprot id: A0A8B6YNP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:PTGER2
gene id: 419612:PTGER2
uniprot id: A0A8B8T6Q9
uniprot id: S9Y9L3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:SRF
gene id: 419612:SRF
uniprot id: A0A8B8RME8
names: Subcellular Location Annotation
messages: Nucleus

419612:NES
gene id: 419612:NES
uniprot id: A0A8B8RRD6
names: Similarity
messages: Belongs to the intermediate filament family.

419612:AP4M1
gene id: 419612:AP4M1
uniprot id: A0A8B6YCN2
uniprot id: A0A8B8RCC4
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

419612:GJD4
gene id: 419612:GJD4
uniprot id: A0A8B8SIR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

419612:SEPTIN4
gene id: 419612:SEPTIN4
uniprot id: A0A8B7K7P4
uniprot id: A0A8B7K9W6
uniprot id: A0A8B8UIB2
uniprot id: A0A8B8UIE3
uniprot id: A0A8B8UIT1
uniprot id: A0A8B8UIU6
uniprot id: A0A8B8UIV1
uniprot id: A0A8B8UJJ9
uniprot id: A0A8B8UJK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

419612:PAQR8
gene id: 419612:PAQR8
uniprot id: S9W800
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

419612:HOXC5
gene id: 419612:HOXC5
uniprot id: A0A8B6YEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

419612:LOC102522963
gene id: 419612:LOC102522963
uniprot id: A0A8B8U230
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

419612:PFKFB1
gene id: 419612:PFKFB1
uniprot id: A0A8B8SLB7
uniprot id: A0A8B8SLC1
uniprot id: A0A8B8SLC9
uniprot id: A0A8B8SLD4
uniprot id: A0A8B8SMF6
uniprot id: A0A8B8SMG1
uniprot id: A0A8B8SMG6
uniprot id: A0A8B8SMQ5
uniprot id: A0A8B8SMR0
uniprot id: A0A8B8SMR5
uniprot id: A0A8B8SNL2
uniprot id: A0A8B8SNL7
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

419612:CLDN8
gene id: 419612:CLDN8
uniprot id: S9W622
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

419612:DDB2
gene id: 419612:DDB2
uniprot id: A0A8B6YLQ3
uniprot id: A0A8B7KDJ1
uniprot id: A0A8B8TQG1
uniprot id: A0A8B8TR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

419612:CBFA2T2
gene id: 419612:CBFA2T2
uniprot id: A0A8B8RJ82
uniprot id: A0A8B8RL18
uniprot id: A0A8B8RLH9
names: Similarity
messages: Belongs to the CBFA2T family.

419612:LOC102510874
gene id: 419612:LOC102510874
uniprot id: A0A8B6YKE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102504321
gene id: 419612:LOC102504321
uniprot id: A0A8B7KHY9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ASF1A
gene id: 419612:ASF1A
uniprot id: A0A8B8TEL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

419612:FGD4
gene id: 419612:FGD4
uniprot id: A0A8B6YEX0
uniprot id: A0A8B8SF65
uniprot id: A0A8B8SF71
uniprot id: A0A8B8SF77
uniprot id: A0A8B8SGD1
uniprot id: A0A8B8SGF9
uniprot id: A0A8B8SHS6
names: Subcellular Location Annotation
messages: cytoskeleton

419612:QRSL1
gene id: 419612:QRSL1
uniprot id: A0A8B6YJN0
uniprot id: A0A8B8TE49
uniprot id: A0A8B8TE51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

419612:MRPL16
gene id: 419612:MRPL16
uniprot id: A0A8B8TSX6
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

419612:TULP2
gene id: 419612:TULP2
uniprot id: A0A8B8TN82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

419612:TRMT1
gene id: 419612:TRMT1
uniprot id: A0A8B8RTV4
uniprot id: A0A8B8RTV7
uniprot id: A0A8B8RUW7
uniprot id: A0A8B8RVR0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

419612:CSGALNACT1
gene id: 419612:CSGALNACT1
uniprot id: A0A8B8S318
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

419612:KLC2
gene id: 419612:KLC2
uniprot id: A0A8B8TU17
uniprot id: T0NJE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

419612:LOC116661933
gene id: 419612:LOC116661933
uniprot id: A0A8B8SMU2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:LOC102505089
gene id: 419612:LOC102505089
uniprot id: A0A8B8SMZ9
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:ERH
gene id: 419612:ERH
uniprot id: A0A8B8T889
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

419612:ATP6V1E1
gene id: 419612:ATP6V1E1
uniprot id: A0A8B8SI03
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

419612:LOC102516204
gene id: 419612:LOC102516204
uniprot id: A0A8B6YGR6
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:SLC12A5
gene id: 419612:SLC12A5
uniprot id: A0A8B7KDY9
uniprot id: A0A8B8RGS9
uniprot id: A0A8B8RIR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

419612:ARAP2
gene id: 419612:ARAP2
uniprot id: A0A8B8UA30
uniprot id: A0A8B8UA35
names: Subcellular Location Annotation
messages: Cytoplasm

419612:ADAMTS5
gene id: 419612:ADAMTS5
uniprot id: A0A8B7KAU8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:MALL
gene id: 419612:MALL
uniprot id: A0A8B6YFM2
names: Subcellular Location Annotation
messages: Membrane

419612:MTMR2
gene id: 419612:MTMR2
uniprot id: A0A8B6YH34
uniprot id: A0A8B6YHE3
uniprot id: A0A8B7KBD5
uniprot id: A0A8B8TPJ2
uniprot id: A0A8B8TQ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

419612:SUSD3
gene id: 419612:SUSD3
uniprot id: A0A8B8ST58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SUPV3L1
gene id: 419612:SUPV3L1
uniprot id: A0A8B6YCK5
uniprot id: A0A8B7K7H9
uniprot id: A0A8B8TYS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

419612:LOC102519376
gene id: 419612:LOC102519376
uniprot id: A0A8B6YP54
uniprot id: A0A8B7KG90
uniprot id: A0A8B7KGF9
uniprot id: A0A8B7KHH0
uniprot id: A0A8B8RTJ4
uniprot id: A0A8B8RUI4
uniprot id: A0A8B8RV55
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:EGR2
gene id: 419612:EGR2
uniprot id: A0A8B8TYH6
uniprot id: A0A8B8TZI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

419612:LOC116663192
gene id: 419612:LOC116663192
uniprot id: A0A8B8SV06
uniprot id: A0A8B8SVC5
uniprot id: A0A8B8SVS1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:LOC116663394
gene id: 419612:LOC116663394
uniprot id: A0A8B8SZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ADAM8
gene id: 419612:ADAM8
uniprot id: A0A8B7K626
uniprot id: A0A8B7K6E2
uniprot id: A0A8B8TW07
uniprot id: A0A8B8TW08
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:ANTXR1
gene id: 419612:ANTXR1
uniprot id: A0A8B8UGA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

419612:LOC102503562
gene id: 419612:LOC102503562
uniprot id: A0A8B8SI26
names: Similarity
messages: Belongs to the CSN9 family.

419612:ATP13A1
gene id: 419612:ATP13A1
uniprot id: A0A8B6Y994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

419612:TRPT1
gene id: 419612:TRPT1
uniprot id: A0A8B6Y8J2
uniprot id: A0A8B8TTJ2
uniprot id: A0A8B8TUL8
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

419612:LOC102506501
gene id: 419612:LOC102506501
uniprot id: A0A8B6Y920
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:KIZ
gene id: 419612:KIZ
uniprot id: A0A8B8RIB7
uniprot id: A0A8B8RK07
uniprot id: A0A8B8RKF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

419612:TRPV2
gene id: 419612:TRPV2
uniprot id: A0A8B8UK17
uniprot id: A0A8B8UK47
names: Subcellular Location Annotation
messages: Membrane

419612:SEMA5B
gene id: 419612:SEMA5B
uniprot id: A0A8B8T2K9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:FADS1
gene id: 419612:FADS1
uniprot id: A0A8B6Y627
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

419612:ESYT3
gene id: 419612:ESYT3
uniprot id: A0A8B8TMV4
uniprot id: A0A8B8TND7
uniprot id: A0A8B8TP21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:LOC106728789
gene id: 419612:LOC106728789
uniprot id: A0A8B8TVL8
uniprot id: A0A8B8TWY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ARL4D
gene id: 419612:ARL4D
uniprot id: S9XET2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

419612:RPL13
gene id: 419612:RPL13
uniprot id: A0A8B8RTF5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

419612:IMPACT
gene id: 419612:IMPACT
uniprot id: A0A8B8RYL9
uniprot id: A0A8B8RYM6
uniprot id: A0A8B8S006
uniprot id: A0A8B8S0A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

419612:LOC116666693
gene id: 419612:LOC116666693
uniprot id: A0A8B8TWW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SKIV2L
gene id: 419612:SKIV2L
uniprot id: A0A8B6YBD9
names: Subcellular Location Annotation
messages: Cytoplasm

419612:LOC116660095
gene id: 419612:LOC116660095
uniprot id: A0A8B8S396
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:SFXN1
gene id: 419612:SFXN1
uniprot id: A0A8B8RSM3
uniprot id: A0A8B8RSN0
uniprot id: A0A8B8RUK8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

419612:POLR2L
gene id: 419612:POLR2L
uniprot id: A0A8B8TV51
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

419612:PHLDA3
gene id: 419612:PHLDA3
uniprot id: A0A8B8RXV2
names: Subcellular Location Annotation
messages: Cytoplasm

419612:SHCBP1L
gene id: 419612:SHCBP1L
uniprot id: A0A8B8RNF0
uniprot id: A0A8B8RNT7
uniprot id: A0A8B8RQ43
uniprot id: A0A8B8RQI6
names: Subcellular Location Annotation
messages: spindle

419612:PEX10
gene id: 419612:PEX10
uniprot id: A0A8B6YJ42
uniprot id: A0A8B8U8E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

419612:EHF
gene id: 419612:EHF
uniprot id: A0A8B7KIK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:KRT74
gene id: 419612:KRT74
uniprot id: A0A8B6YEN2
names: Similarity
messages: Belongs to the intermediate filament family.

419612:GRPEL1
gene id: 419612:GRPEL1
uniprot id: A0A8B6Y7Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

419612:CMAS
gene id: 419612:CMAS
uniprot id: A0A8B8SHH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
messages: Homotetramer; the active enzyme is formed by a dimer of dimers.

419612:POLR3A
gene id: 419612:POLR3A
uniprot id: A0A8B6YBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

419612:WDR48
gene id: 419612:WDR48
uniprot id: A0A8B8RAR9
uniprot id: A0A8B8RAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Late endosome

419612:LOC102515219
gene id: 419612:LOC102515219
uniprot id: S9YG98
names: Similarity
messages: Belongs to the TACO1 family.

419612:LOC116667620
gene id: 419612:LOC116667620
uniprot id: A0A8B8U357
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MMP23B
gene id: 419612:MMP23B
uniprot id: A0A8B8U8A9
uniprot id: A0A8B8U8B1
uniprot id: A0A8B8U9G1
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MYB
gene id: 419612:MYB
uniprot id: A0A8B6YIU2
uniprot id: A0A8B6YK50
uniprot id: A0A8B8TF55
uniprot id: A0A8B8TF56
uniprot id: A0A8B8TGI0
names: Subcellular Location Annotation
messages: Nucleus

419612:VKORC1
gene id: 419612:VKORC1
uniprot id: A0A8B6YCF8
uniprot id: T0MFB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:LOC102518414
gene id: 419612:LOC102518414
uniprot id: A0A8B6YQ21
names: Similarity
messages: Belongs to the PRAME family.

419612:B3GNT8
gene id: 419612:B3GNT8
uniprot id: A0A8B6YLB5
uniprot id: A0A8B8TI09
uniprot id: A0A8B8TJA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:EFNA2
gene id: 419612:EFNA2
uniprot id: A0A8B8RXH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC106730948
gene id: 419612:LOC106730948
uniprot id: S9W627
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:MRPS9
gene id: 419612:MRPS9
uniprot id: A0A8B6Y5V3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

419612:CSMD3
gene id: 419612:CSMD3
uniprot id: A0A8B8S1D1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:ACVR1C
gene id: 419612:ACVR1C
uniprot id: A0A8B8SZC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

419612:JPT1
gene id: 419612:JPT1
uniprot id: A0A8B8R414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

419612:LOC116661249
gene id: 419612:LOC116661249
uniprot id: A0A8B8SEP1
uniprot id: A0A8B8SFU2
names: Subcellular Location Annotation
messages: Membrane

419612:SNED1
gene id: 419612:SNED1
uniprot id: A0A8B8T2W2
uniprot id: A0A8B8T2W8
uniprot id: A0A8B8T2W9
uniprot id: A0A8B8T2X2
uniprot id: A0A8B8T391
uniprot id: A0A8B8T3M0
uniprot id: A0A8B8T3M5
uniprot id: A0A8B8T3N0
uniprot id: A0A8B8T3P7
uniprot id: A0A8B8T3Q2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:FAM151B
gene id: 419612:FAM151B
uniprot id: A0A8B6YHC3
uniprot id: A0A8B8SLN0
uniprot id: A0A8B8SLP2
uniprot id: A0A8B8SLP7
names: Similarity
messages: Belongs to the FAM151 family.

419612:SLC5A5
gene id: 419612:SLC5A5
uniprot id: A0A8B8RUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

419612:LOC102520743
gene id: 419612:LOC102520743
uniprot id: A0A8B6YP39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:AMER2
gene id: 419612:AMER2
uniprot id: A0A8B8UDX3
names: Similarity
messages: Belongs to the Amer family.

419612:FLNB
gene id: 419612:FLNB
uniprot id: A0A8B8R821
names: Similarity
messages: Belongs to the filamin family.

419612:GPD1L
gene id: 419612:GPD1L
uniprot id: A0A8B8RBA1
uniprot id: A0A8B8RBA4
uniprot id: A0A8B8RDD5
uniprot id: A0A8B8RDX2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

419612:SLC17A1
gene id: 419612:SLC17A1
uniprot id: A0A8B8RKZ8
names: Subcellular Location Annotation
messages: Membrane

419612:HSF4
gene id: 419612:HSF4
uniprot id: A0A8B8TJG7
uniprot id: A0A8B8TJH5
uniprot id: A0A8B8TJI0
uniprot id: A0A8B8TJP9
uniprot id: A0A8B8TKP7
uniprot id: A0A8B8TKQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

419612:LOC116659120
gene id: 419612:LOC116659120
uniprot id: A0A8B8RW95
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:DCSTAMP
gene id: 419612:DCSTAMP
uniprot id: A0A8B8S287
names: Subcellular Location Annotation
messages: Membrane

419612:UBE2M
gene id: 419612:UBE2M
uniprot id: A0A8B7KEA7
uniprot id: A0A8B8TM89
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:LOC102522758
gene id: 419612:LOC102522758
uniprot id: A0A8B6YMK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SMO
gene id: 419612:SMO
uniprot id: A0A8B8TAC9
uniprot id: A0A8B8TAD0
uniprot id: A0A8B8TAS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium

419612:CA8
gene id: 419612:CA8
uniprot id: A0A8B8S689
uniprot id: A0A8B8S695
uniprot id: A0A8B8S8B9
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

419612:VNN3
gene id: 419612:VNN3
uniprot id: A0A8B6YJ02
uniprot id: A0A8B8TF25
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

419612:TNFSF8
gene id: 419612:TNFSF8
uniprot id: A0A8B6YHU2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

419612:PAX9
gene id: 419612:PAX9
uniprot id: A0A8B8T6L9
names: Subcellular Location Annotation
messages: Nucleus

419612:CCNL1
gene id: 419612:CCNL1
uniprot id: A0A8B8TH11
uniprot id: A0A8B8TH55
names: Similarity
messages: Belongs to the cyclin family.

419612:FBXO46
gene id: 419612:FBXO46
uniprot id: A0A8B8THF7
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

419612:LOC102516917
gene id: 419612:LOC102516917
uniprot id: A0A8B6Y7W1
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

419612:TFPI2
gene id: 419612:TFPI2
uniprot id: A0A8B7KFX6
names: Subcellular Location Annotation
messages: Secreted

419612:NEK8
gene id: 419612:NEK8
uniprot id: A0A8B8R684
uniprot id: A0A8B8R685
uniprot id: A0A8B8R689
uniprot id: A0A8B8R6E6
uniprot id: A0A8B8R8Z2
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

419612:VPS26A
gene id: 419612:VPS26A
uniprot id: A0A8B8TYP0
uniprot id: A0A8B8U002
names: Similarity
messages: Belongs to the VPS26 family.

419612:MFSD10
gene id: 419612:MFSD10
uniprot id: A0A8B8U2W9
uniprot id: A0A8B8U3I7
uniprot id: A0A8B8U3K6
uniprot id: A0A8B8U457
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

419612:APOC4
gene id: 419612:APOC4
uniprot id: A0A8B8TIW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C4 family.
messages: May participate in lipoprotein metabolism.
messages: Secreted

419612:CETN1
gene id: 419612:CETN1
uniprot id: S9XP50
names: Similarity
messages: Belongs to the centrin family.

419612:FAM216A
gene id: 419612:FAM216A
uniprot id: A0A8B6YAR5
uniprot id: A0A8B7K5L3
uniprot id: A0A8B8SCG7
names: Similarity
messages: Belongs to the FAM216 family.

419612:C3H5orf24
gene id: 419612:C3H5orf24
uniprot id: A0A8B6YC44
uniprot id: A0A8B8SSB7
names: Similarity
messages: Belongs to the UPF0461 family.

419612:UBE4B
gene id: 419612:UBE4B
uniprot id: A0A8B6YBJ0
uniprot id: A0A8B6YF33
uniprot id: A0A8B8UA43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm
messages: The U-box domain is required for the ubiquitin protein ligase activity.
messages: Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. Also functions as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.

419612:PTGES3L
gene id: 419612:PTGES3L
uniprot id: A0A8B7K3F0
uniprot id: A0A8B7K3R2
uniprot id: A0A8B7K5W7
uniprot id: A0A8B8R585
names: Similarity
messages: Belongs to the p23/wos2 family.

419612:OXSM
gene id: 419612:OXSM
uniprot id: A0A8B8TPX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
messages: Mitochondrion

419612:ANO1
gene id: 419612:ANO1
uniprot id: A0A8B8TVM9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:A4GNT
gene id: 419612:A4GNT
uniprot id: A0A8B6Y9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

419612:SHROOM4
gene id: 419612:SHROOM4
uniprot id: A0A8B8SN27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

419612:BTK
gene id: 419612:BTK
uniprot id: A0A8B6YNE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

419612:LOC102507402
gene id: 419612:LOC102507402
uniprot id: A0A8B8STK9
names: Similarity
messages: Belongs to the MHC class I family.

419612:FGA
gene id: 419612:FGA
uniprot id: A0A8B7KE68
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

419612:NGB
gene id: 419612:NGB
uniprot id: A0A8B6YFF2
uniprot id: A0A8B8T8D5
names: Similarity
messages: Belongs to the globin family.

419612:ZACN
gene id: 419612:ZACN
uniprot id: A0A8B6Y9H8
names: Subcellular Location Annotation
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:GOLPH3
gene id: 419612:GOLPH3
uniprot id: A0A8B8S8F1
uniprot id: A0A8B8S8G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

419612:MRGPRD
gene id: 419612:MRGPRD
uniprot id: A0A8B6Y6A8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:TMED1
gene id: 419612:TMED1
uniprot id: A0A8B6YFH2
uniprot id: A0A8B8RVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

419612:NDRG3
gene id: 419612:NDRG3
uniprot id: A0A8B8RJL4
uniprot id: A0A8B8RJM1
uniprot id: A0A8B8RLF1
uniprot id: A0A8B8RLW7
names: Similarity
messages: Belongs to the NDRG family.

419612:LIPC
gene id: 419612:LIPC
uniprot id: A0A8B8T3Z2
uniprot id: A0A8B8T3Z4
uniprot id: A0A8B8T4S8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

419612:TARBP2
gene id: 419612:TARBP2
uniprot id: A0A8B6YEL4
uniprot id: A0A8B8U2T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Nucleus
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. Interacts with EIF2AK2/PKR and inhibits its protein kinase activity. Interacts with DHX9 and PRKRA. Interacts with DICER1, AGO2, MOV10, EIF6 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC).
messages: perinuclear region

419612:BARX2
gene id: 419612:BARX2
uniprot id: A0A8B8SDW3
uniprot id: A0A8B8SF27
uniprot id: A0A8B8SGG2
names: Subcellular Location Annotation
messages: Nucleus

419612:PLOD1
gene id: 419612:PLOD1
uniprot id: A0A8B7KEY5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

419612:FAM205C
gene id: 419612:FAM205C
uniprot id: A0A8B6YI84
names: Similarity
messages: Belongs to the SPATA31 family.

419612:TTC39A
gene id: 419612:TTC39A
uniprot id: A0A8B8U6C4
uniprot id: A0A8B8U6C8
uniprot id: A0A8B8U796
names: Similarity
messages: Belongs to the TTC39 family.

419612:AFF2
gene id: 419612:AFF2
uniprot id: A0A8B8SL94
names: Similarity
messages: Belongs to the AF4 family.

419612:IFRD1
gene id: 419612:IFRD1
uniprot id: A0A8B6YJE1
uniprot id: A0A8B8TBD0
uniprot id: A0A8B8TBH6
uniprot id: A0A8B8TBQ7
uniprot id: A0A8B8TCJ7
names: Similarity
messages: Belongs to the IFRD family.

419612:TPM1
gene id: 419612:TPM1
uniprot id: A0A8B8T3Q4
uniprot id: A0A8B8T3Q8
uniprot id: A0A8B8T3Q9
uniprot id: A0A8B8T3R3
uniprot id: A0A8B8T3R4
uniprot id: A0A8B8T3R8
uniprot id: A0A8B8T3R9
uniprot id: A0A8B8T3S3
uniprot id: A0A8B8T3S4
uniprot id: A0A8B8T3S8
uniprot id: A0A8B8T419
uniprot id: A0A8B8T424
uniprot id: A0A8B8T429
uniprot id: A0A8B8T434
uniprot id: A0A8B8T438
uniprot id: A0A8B8T443
uniprot id: A0A8B8T4H6
uniprot id: A0A8B8T4I1
uniprot id: A0A8B8T4I3
uniprot id: A0A8B8T4J0
uniprot id: A0A8B8T4J2
uniprot id: A0A8B8T4J4
uniprot id: A0A8B8T4J7
uniprot id: A0A8B8T4K0
uniprot id: A0A8B8T4K4
uniprot id: A0A8B8T4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

419612:LOC102506546
gene id: 419612:LOC102506546
uniprot id: A0A8B7KAN2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

419612:ATG7
gene id: 419612:ATG7
uniprot id: A0A8B8RA59
uniprot id: A0A8B8RC91
uniprot id: A0A8B8RCV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress.
messages: Homodimer.
messages: Preautophagosomal structure

419612:AUP1
gene id: 419612:AUP1
uniprot id: A0A8B6Y8L7
uniprot id: A0A8B7K6J6
uniprot id: A0A8B8UGW6
uniprot id: A0A8B8UHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AUP1 family.
messages: Membrane

419612:LOC116666869
gene id: 419612:LOC116666869
uniprot id: A0A8B8TX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:TSSC4
gene id: 419612:TSSC4
uniprot id: A0A8B8TUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TSSC4 family.
messages: Cytoplasm
messages: Nucleus

419612:MSRB3
gene id: 419612:MSRB3
uniprot id: A0A8B8U3R3
uniprot id: A0A8B8U3S4
uniprot id: A0A8B8U4H1
uniprot id: A0A8B8U4Y2
uniprot id: A0A8B8U4Y7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

419612:SNX18
gene id: 419612:SNX18
uniprot id: A0A8B6YKG5
uniprot id: A0A8B8SCS9
uniprot id: A0A8B8SCT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

419612:PLA2G15
gene id: 419612:PLA2G15
uniprot id: A0A8B6YBM7
uniprot id: A0A8B8TJS6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

419612:PSME1
gene id: 419612:PSME1
uniprot id: A0A8B8T5X1
names: Similarity
messages: Belongs to the PA28 family.

419612:LOC102522922
gene id: 419612:LOC102522922
uniprot id: A0A8B8S940
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:LOC102522779
gene id: 419612:LOC102522779
uniprot id: A0A8B8TVQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC116657154
gene id: 419612:LOC116657154
uniprot id: A0A8B8RB82
uniprot id: A0A8B8RBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

419612:LOC106728977
gene id: 419612:LOC106728977
uniprot id: A0A8B7K6G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102509144
gene id: 419612:LOC102509144
uniprot id: A0A8B6Y959
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PDGFRA
gene id: 419612:PDGFRA
uniprot id: A0A8B8UGQ7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

419612:LOC102507588
gene id: 419612:LOC102507588
uniprot id: A0A8B8RN80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

419612:SETD1B
gene id: 419612:SETD1B
uniprot id: A0A8B8SCA9
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

419612:TUBB1
gene id: 419612:TUBB1
uniprot id: S9YRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

419612:RPS9
gene id: 419612:RPS9
uniprot id: S9XH97
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

419612:LOC116666896
gene id: 419612:LOC116666896
uniprot id: A0A8B8TW28
names: Similarity
messages: Belongs to the JAKMIP family.

419612:SPOCK1
gene id: 419612:SPOCK1
uniprot id: A0A8B8SRD5
uniprot id: A0A8B8SS31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:KEG61 p06
gene id: 419612:KEG61_p06
uniprot id: A0A8B9B712
uniprot id: A6YAS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

419612:LOC102516561
gene id: 419612:LOC102516561
uniprot id: A0A8B7KF20
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

419612:EHD3
gene id: 419612:EHD3
uniprot id: A0A8B6YI51
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

419612:LOC116660886
gene id: 419612:LOC116660886
uniprot id: S9YD57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:SLC45A3
gene id: 419612:SLC45A3
uniprot id: A0A8B8RZP2
names: Subcellular Location Annotation
messages: Membrane

419612:LSM4
gene id: 419612:LSM4
uniprot id: A0A8B6YGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

419612:LOC102513452
gene id: 419612:LOC102513452
uniprot id: A0A8B7KH77
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:ELP6
gene id: 419612:ELP6
uniprot id: A0A8B8R9A4
names: Similarity
messages: Belongs to the ELP6 family.

419612:OLFM4
gene id: 419612:OLFM4
uniprot id: S9XA10
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:RSBN1L
gene id: 419612:RSBN1L
uniprot id: A0A8B8TCT5
uniprot id: A0A8B8TCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

419612:ATP6V1F
gene id: 419612:ATP6V1F
uniprot id: A0A8B6YFQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

419612:NRF1
gene id: 419612:NRF1
uniprot id: S9X047
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

419612:IL12A
gene id: 419612:IL12A
uniprot id: A0A8B6YKH2
uniprot id: A0A8B8THP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes. As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine. Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites.
messages: Secreted

419612:CRELD1
gene id: 419612:CRELD1
uniprot id: A0A8B8RCS5
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:RBM10
gene id: 419612:RBM10
uniprot id: A0A8B8SJG3
uniprot id: A0A8B8SLV4
names: Subcellular Location Annotation
messages: Nucleus

419612:PKNOX2
gene id: 419612:PKNOX2
uniprot id: A0A8B8SGR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

419612:DDIT4L
gene id: 419612:DDIT4L
uniprot id: A0A8B6YPC6
uniprot id: A0A8B7KGI5
names: Similarity
messages: Belongs to the DDIT4 family.

419612:ATG2A
gene id: 419612:ATG2A
uniprot id: A0A8B7K6I5
uniprot id: A0A8B8TUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

419612:SCAMP3
gene id: 419612:SCAMP3
uniprot id: A0A8B6Y8S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

419612:MAP3K13
gene id: 419612:MAP3K13
uniprot id: A0A8B8T9B4
uniprot id: A0A8B8T9B9
names: Function
names: Similarity
messages: Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

419612:LOC116669038
gene id: 419612:LOC116669038
uniprot id: A0A8B8UGP6
uniprot id: A0A8B8UGQ1
uniprot id: A0A8B8UHB7
uniprot id: A0A8B8UHC3
uniprot id: A0A8B8UI19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cell cortex
messages: cytoskeleton

419612:WNT7A
gene id: 419612:WNT7A
uniprot id: A0A8B8R9G3
uniprot id: A0A8B8R9K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

419612:LOC106729813
gene id: 419612:LOC106729813
uniprot id: A0A8B8RGP7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

419612:NEIL1
gene id: 419612:NEIL1
uniprot id: A0A8B7K8P6
uniprot id: A0A8B8S742
names: Similarity
messages: Belongs to the FPG family.

419612:MLST8
gene id: 419612:MLST8
uniprot id: A0A8B7KCW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of the mammalian target of rapamycin complex 1 (mTORC1) which contains MTOR, MLST8, RPTOR, AKT1S1/PRAS40 and DEPTOR. mTORC1 binds to and is inhibited by FKBP12-rapamycin. Part of the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. Contrary to mTORC1, mTORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Interacts directly with MTOR and RPTOR. Interacts with RHEB. Interacts with MEAK7. Interacts with SIK3.
messages: Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, LST8 interacts directly with MTOR and enhances its kinase activity. In nutrient-poor conditions, stabilizes the MTOR-RPTOR interaction and favors RPTOR-mediated inhibition of MTOR activity. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1. mTORC2 also modulates the phosphorylation of PRKCA.

419612:PAM
gene id: 419612:PAM
uniprot id: A0A8B8SQ64
uniprot id: A0A8B8SQ78
uniprot id: A0A8B8SQ84
uniprot id: A0A8B8SQ89
uniprot id: A0A8B8SQZ7
uniprot id: A0A8B8SR02
uniprot id: A0A8B8SRD1
uniprot id: A0A8B8SRD6
uniprot id: A0A8B8SS68
uniprot id: A0A8B8SS74
uniprot id: A0A8B8SS79
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 2 Cu(2+) ions per subunit.
messages: Binds one Zn(2+) ion per subunit.
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Membrane
messages: secretory vesicle membrane

419612:LOC102513223
gene id: 419612:LOC102513223
uniprot id: A0A8B6Y969
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MLLT1
gene id: 419612:MLLT1
uniprot id: A0A8B8RUN3
uniprot id: A0A8B8RVS8
names: Subcellular Location Annotation
messages: Nucleus

419612:MED25
gene id: 419612:MED25
uniprot id: A0A8B8TGL9
uniprot id: A0A8B8TGM9
uniprot id: A0A8B8TGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 25 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

419612:CUBN
gene id: 419612:CUBN
uniprot id: A0A8B8SJK2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:STK4
gene id: 419612:STK4
uniprot id: S9W7S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

419612:FSCN1
gene id: 419612:FSCN1
uniprot id: A0A8B8RD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

419612:STOML1
gene id: 419612:STOML1
uniprot id: A0A8B8S4X5
uniprot id: A0A8B8S676
uniprot id: A0A8B8S6F3
uniprot id: A0A8B8S6W3
uniprot id: A0A8B8S6W7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

419612:PLPP5
gene id: 419612:PLPP5
uniprot id: A0A8B7K9L8
uniprot id: A0A8B8S2Q0
uniprot id: A0A8B8S420
uniprot id: A0A8B8S4A8
uniprot id: A0A8B8S4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

419612:USP45
gene id: 419612:USP45
uniprot id: A0A8B8TDI2
uniprot id: A0A8B8TDJ1
uniprot id: A0A8B8TDN9
uniprot id: A0A8B8TES1
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

419612:GGT5
gene id: 419612:GGT5
uniprot id: A0A8B7K532
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

419612:MMP26
gene id: 419612:MMP26
uniprot id: A0A8B6YE12
uniprot id: A0A8B8TVM5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

419612:ARL5B
gene id: 419612:ARL5B
uniprot id: A0A8B8SIF9
uniprot id: A0A8B8SJJ2
uniprot id: A0A8B8SKW7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

419612:SARS2
gene id: 419612:SARS2
uniprot id: A0A8B8TIC6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

419612:C8H6orf58
gene id: 419612:C8H6orf58
uniprot id: A0A8B8TET8
uniprot id: A0A8B8TET9
uniprot id: A0A8B8TEU3
uniprot id: A0A8B8TEU4
uniprot id: A0A8B8TEU5
uniprot id: A0A8B8TEU8
uniprot id: A0A8B8TEV0
uniprot id: A0A8B8TEV2
uniprot id: A0A8B8TEV4
uniprot id: A0A8B8TEX8
uniprot id: A0A8B8TEY3
uniprot id: A0A8B8TEY9
uniprot id: A0A8B8TG53
uniprot id: A0A8B8TG59
uniprot id: A0A8B8TG64
uniprot id: A0A8B8TG69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

419612:LOC102522729
gene id: 419612:LOC102522729
uniprot id: S9WA64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SLC22A1
gene id: 419612:SLC22A1
uniprot id: A0A8B6YBL6
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

419612:ELF1
gene id: 419612:ELF1
uniprot id: A0A8B6Y8C4
uniprot id: A0A8B8UBF7
uniprot id: A0A8B8UBF9
uniprot id: A0A8B8UC74
uniprot id: A0A8B8UCB7
uniprot id: A0A8B8UCT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:GLA
gene id: 419612:GLA
uniprot id: A0A8B6YLU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

419612:LOC102519686
gene id: 419612:LOC102519686
uniprot id: S9XUS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MEF2B
gene id: 419612:MEF2B
uniprot id: A0A8B8RSZ1
names: Subcellular Location Annotation
messages: Nucleus

419612:FCHO1
gene id: 419612:FCHO1
uniprot id: A0A8B8RU90
uniprot id: A0A8B8RV77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

419612:CHST14
gene id: 419612:CHST14
uniprot id: A0A8B6Y9K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:PTBP1
gene id: 419612:PTBP1
uniprot id: A0A8B8RVU3
uniprot id: A0A8B8RX06
uniprot id: A0A8B8RXB3
names: Subcellular Location Annotation
messages: Nucleus

419612:XRCC1
gene id: 419612:XRCC1
uniprot id: A0A8B7K3P3
uniprot id: A0A8B7K3W0
names: Subcellular Location Annotation
messages: Nucleus

419612:TMEM106A
gene id: 419612:TMEM106A
uniprot id: A0A8B6Y8G5
names: Similarity
messages: Belongs to the TMEM106 family.

419612:TMEM184C
gene id: 419612:TMEM184C
uniprot id: A0A8B6YPP0
names: Subcellular Location Annotation
messages: Membrane

419612:SIRT5
gene id: 419612:SIRT5
uniprot id: A0A8B6YDT8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-102 and Arg-105) that bind to malonylated and succinylated substrates and define the specificity.
messages: Mitochondrion
messages: Monomer. Homodimer. Interacts with CPS1.
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinylation and activation of HMGCS2. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as Uox.
messages: Nucleus
messages: cytosol

419612:TOR1B
gene id: 419612:TOR1B
uniprot id: A0A8B8SWT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

419612:LOC106729945
gene id: 419612:LOC106729945
uniprot id: S9XF09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MYH6
gene id: 419612:MYH6
uniprot id: A0A8B8T5U0
uniprot id: A0A8B8T6F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

419612:KALRN
gene id: 419612:KALRN
uniprot id: A0A8B8T2I4
uniprot id: A0A8B8T2L1
uniprot id: A0A8B8T2M7
uniprot id: A0A8B8T2N8
uniprot id: A0A8B8T2Q4
uniprot id: A0A8B8T2R9
uniprot id: A0A8B8T2T0
uniprot id: A0A8B8T2T4
uniprot id: A0A8B8T2X7
uniprot id: A0A8B8T379
uniprot id: A0A8B8T3A5
uniprot id: A0A8B8T3B3
uniprot id: A0A8B8T3D2
uniprot id: A0A8B8T3E3
uniprot id: A0A8B8T3J9
uniprot id: A0A8B8T3Q6
uniprot id: A0A8B8T3T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

419612:ENTPD1
gene id: 419612:ENTPD1
uniprot id: A0A8B7KG87
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

419612:GDA
gene id: 419612:GDA
uniprot id: A0A8B6YP84
uniprot id: A0A8B7KG75
uniprot id: A0A8B8SV76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

419612:CDC37L1
gene id: 419612:CDC37L1
uniprot id: A0A8B6Y9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

419612:LOC116663681
gene id: 419612:LOC116663681
uniprot id: A0A8B8T048
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

419612:CSTA
gene id: 419612:CSTA
uniprot id: A0A8B6YLE2
names: Similarity
messages: Belongs to the cystatin family.

419612:TRIM46
gene id: 419612:TRIM46
uniprot id: A0A8B8RPZ7
uniprot id: A0A8B8RQI5
names: Subcellular Location Annotation
messages: cytoskeleton

419612:MCTP1
gene id: 419612:MCTP1
uniprot id: A0A8B8SPF4
uniprot id: A0A8B8SPG0
uniprot id: A0A8B8SPH2
uniprot id: A0A8B8SPI7
uniprot id: A0A8B8SPJ1
uniprot id: A0A8B8SPK1
uniprot id: A0A8B8SPL6
uniprot id: A0A8B8SQA2
uniprot id: A0A8B8SQA7
uniprot id: A0A8B8SQE0
uniprot id: A0A8B8SQN0
uniprot id: A0A8B8SRI6
uniprot id: A0A8B8SRJ6
names: Subcellular Location Annotation
messages: Membrane

419612:RNPEPL1
gene id: 419612:RNPEPL1
uniprot id: A0A8B8T2T9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

419612:EIF4E1B
gene id: 419612:EIF4E1B
uniprot id: A0A8B7K9A9
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

419612:NUP50
gene id: 419612:NUP50
uniprot id: A0A8B8U155
uniprot id: A0A8B8U2E7
names: Subcellular Location Annotation
messages: nuclear pore complex

419612:CCDC124
gene id: 419612:CCDC124
uniprot id: A0A8B8RT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC124 family.
messages: Midbody

419612:DNAAF1
gene id: 419612:DNAAF1
uniprot id: A0A8B6YEN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
messages: cilium

419612:PHB
gene id: 419612:PHB
uniprot id: A0A8B8R6N7
uniprot id: A0A8B8R8V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

419612:LOC102506848
gene id: 419612:LOC102506848
uniprot id: S9XK09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SCG5
gene id: 419612:SCG5
uniprot id: A0A8B6YQ25
uniprot id: A0A8B6YRY9
uniprot id: A0A8B8T5A2
uniprot id: A0A8B8T5L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
messages: Belongs to the 7B2 family.
messages: Interacts with PCSK2/PC2 early in the secretory pathway. Dissociation occurs at later stages.
messages: Secreted

419612:PRKCI
gene id: 419612:PRKCI
uniprot id: A0A8B8TDM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

419612:CD151
gene id: 419612:CD151
uniprot id: A0A8B8TV50
uniprot id: A0A8B8TV56
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:ARHGAP32
gene id: 419612:ARHGAP32
uniprot id: A0A8B8SDV5
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

419612:PARP14
gene id: 419612:PARP14
uniprot id: A0A8B6YJZ0
uniprot id: A0A8B7KEJ0
names: Similarity
messages: Belongs to the ARTD/PARP family.

419612:PTPN13
gene id: 419612:PTPN13
uniprot id: A0A8B7KDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.
messages: cytoskeleton

419612:NDUFS4
gene id: 419612:NDUFS4
uniprot id: A0A8B6YGG7
uniprot id: A0A8B8SDX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Mitochondrion inner membrane

419612:CMTM4
gene id: 419612:CMTM4
uniprot id: A0A8B8TJE7
names: Subcellular Location Annotation
messages: Membrane

419612:RPL22L1
gene id: 419612:RPL22L1
uniprot id: A0A8B6YIF3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

419612:PPP1R14B
gene id: 419612:PPP1R14B
uniprot id: A0A8B6Y8J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

419612:AMIGO1
gene id: 419612:AMIGO1
uniprot id: S9X8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

419612:LOC102516775
gene id: 419612:LOC102516775
uniprot id: A0A8B8RAR4
uniprot id: A0A8B8RCW0
names: Similarity
messages: Belongs to the peptidase C14A family.

419612:RNF39
gene id: 419612:RNF39
uniprot id: A0A8B8RKR2
names: Subcellular Location Annotation
messages: Cytoplasm

419612:ADCYAP1R1
gene id: 419612:ADCYAP1R1
uniprot id: A0A8B8TBM6
uniprot id: A0A8B8TBM9
uniprot id: A0A8B8TCU8
names: Subcellular Location Annotation
messages: Membrane

419612:UEVLD
gene id: 419612:UEVLD
uniprot id: A0A8B8TR82
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

419612:FOLH1B
gene id: 419612:FOLH1B
uniprot id: A0A8B8TPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

419612:ENTPD7
gene id: 419612:ENTPD7
uniprot id: A0A8B8TXH7
uniprot id: A0A8B8TXH8
uniprot id: A0A8B8TYJ5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

419612:KEAP1
gene id: 419612:KEAP1
uniprot id: T0NQ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

419612:PTCD3
gene id: 419612:PTCD3
uniprot id: A0A8B7K956
uniprot id: A0A8B7K965
uniprot id: A0A8B8S7R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

419612:THG1L
gene id: 419612:THG1L
uniprot id: S9XDY6
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

419612:ZBED9
gene id: 419612:ZBED9
uniprot id: A0A8B6YLW7
names: Subcellular Location Annotation
messages: Nucleus

419612:MCU
gene id: 419612:MCU
uniprot id: A0A8B8S6B3
uniprot id: A0A8B8S6B8
uniprot id: A0A8B8S8E6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

419612:CACNG7
gene id: 419612:CACNG7
uniprot id: A0A8B8TNE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

419612:CETN2
gene id: 419612:CETN2
uniprot id: A0A8B8SLQ9
uniprot id: A0A8B8SM17
names: Similarity
messages: Belongs to the centrin family.

419612:HSD17B13
gene id: 419612:HSD17B13
uniprot id: A0A8B6YK47
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:DEDD2
gene id: 419612:DEDD2
uniprot id: S9YLH7
names: Subcellular Location Annotation
messages: nucleolus

419612:LTC4S
gene id: 419612:LTC4S
uniprot id: A0A8B8RS56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:PYM1
gene id: 419612:PYM1
uniprot id: A0A8B6YEZ2
names: Similarity
names: Subunit
messages: Belongs to the pym family.
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

419612:LOC102516977
gene id: 419612:LOC102516977
uniprot id: A0A8B8TNK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

419612:TAF7L
gene id: 419612:TAF7L
uniprot id: A0A8B8SM57
uniprot id: A0A8B8SN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

419612:NPC1
gene id: 419612:NPC1
uniprot id: A0A8B8S111
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

419612:ADGRV1
gene id: 419612:ADGRV1
uniprot id: A0A8B8SNY3
names: Subcellular Location Annotation
messages: Membrane

419612:FOXO6
gene id: 419612:FOXO6
uniprot id: A0A8B8U6G4
names: Subcellular Location Annotation
messages: Nucleus

419612:CDK2AP1
gene id: 419612:CDK2AP1
uniprot id: A0A8B8SDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

419612:KCNN1
gene id: 419612:KCNN1
uniprot id: A0A8B7K3R3
uniprot id: A0A8B8RT89
uniprot id: A0A8B8RU74
uniprot id: A0A8B8RUV5
names: Subcellular Location Annotation
messages: Membrane

419612:PRKCQ
gene id: 419612:PRKCQ
uniprot id: A0A8B8SI19
uniprot id: A0A8B8SJ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

419612:TEX28
gene id: 419612:TEX28
uniprot id: A0A8B8SNM3
names: Similarity
messages: Belongs to the TEX28 family.

419612:ELL
gene id: 419612:ELL
uniprot id: A0A8B8RUQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

419612:LOC106728570
gene id: 419612:LOC106728570
uniprot id: A0A8B8UJ08
uniprot id: A0A8B8UJF7
uniprot id: A0A8B8UJH8
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

419612:SEMA5A
gene id: 419612:SEMA5A
uniprot id: A0A8B8S6F2
uniprot id: A0A8B8S7W0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:CRH
gene id: 419612:CRH
uniprot id: A0A8B6YRX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

419612:NEK6
gene id: 419612:NEK6
uniprot id: A0A8B6YI36
uniprot id: A0A8B8SWD5
uniprot id: A0A8B8SWU0
uniprot id: A0A8B8SWU5
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:LOC102524454
gene id: 419612:LOC102524454
uniprot id: A0A8B6Y5C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:IL17D
gene id: 419612:IL17D
uniprot id: A0A8B8UDF6
uniprot id: A0A8B8UDG2
uniprot id: A0A8B8UDI0
uniprot id: A0A8B8UDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

419612:LSM1
gene id: 419612:LSM1
uniprot id: A0A8B6YIA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.

419612:RNASE12
gene id: 419612:RNASE12
uniprot id: A0A8B6YL81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

419612:HAAO
gene id: 419612:HAAO
uniprot id: A0A8B6YAU6
uniprot id: A0A8B7K682
uniprot id: A0A8B8UG26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

419612:SPSB3
gene id: 419612:SPSB3
uniprot id: A0A8B8RDG8
uniprot id: A0A8B8RDG9
uniprot id: A0A8B8RDM7
uniprot id: A0A8B8RFJ0
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

419612:CENPA
gene id: 419612:CENPA
uniprot id: A0A8B7KFB0
names: Similarity
messages: Belongs to the histone H3 family.

419612:CDKN2AIP
gene id: 419612:CDKN2AIP
uniprot id: A0A8B6YHZ6
uniprot id: A0A8B8S323
names: Similarity
messages: Belongs to the CARF family.

419612:MS4A7
gene id: 419612:MS4A7
uniprot id: A0A8B6YRV0
names: Similarity
messages: Belongs to the MS4A family.

419612:TRH
gene id: 419612:TRH
uniprot id: A0A8B8RA80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

419612:PSMA2
gene id: 419612:PSMA2
uniprot id: A0A8B6YM26
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

419612:AFP
gene id: 419612:AFP
uniprot id: A0A8B8RWE6
names: Subcellular Location Annotation
messages: Secreted

419612:KMT5A
gene id: 419612:KMT5A
uniprot id: A0A8B8SCY0
uniprot id: A0A8B8SCY1
uniprot id: A0A8B8SFE8
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

419612:ADAMTS17
gene id: 419612:ADAMTS17
uniprot id: A0A8B8S4R4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:BABAM1
gene id: 419612:BABAM1
uniprot id: A0A8B6Y888
uniprot id: A0A8B8RTD6
uniprot id: A0A8B8RVA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

419612:INPP1
gene id: 419612:INPP1
uniprot id: A0A8B7KBK7
uniprot id: A0A8B8T0M3
uniprot id: S9YBM7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

419612:PCK1
gene id: 419612:PCK1
uniprot id: A0A8B6YGQ8
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

419612:TCF25
gene id: 419612:TCF25
uniprot id: A0A8B8RRL1
uniprot id: A0A8B8RSA2
names: Similarity
messages: Belongs to the TCF25 family.

419612:RAMP1
gene id: 419612:RAMP1
uniprot id: A0A8B8T3H8
names: Similarity
messages: Belongs to the RAMP family.

419612:CRABP2
gene id: 419612:CRABP2
uniprot id: A0A8B6Y744
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

419612:LOC102523029
gene id: 419612:LOC102523029
uniprot id: A0A8B6YPW7
uniprot id: A0A8B7KE77
uniprot id: A0A8B7KFH0
uniprot id: S9XM73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

419612:SLC2A1
gene id: 419612:SLC2A1
uniprot id: A0A8B8U5M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane
messages: Photoreceptor inner segment

419612:LOC102520157
gene id: 419612:LOC102520157
uniprot id: A0A8B8S225
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

419612:GDF6
gene id: 419612:GDF6
uniprot id: A0A8B8S203
names: Similarity
messages: Belongs to the TGF-beta family.

419612:LOC102519616
gene id: 419612:LOC102519616
uniprot id: A0A8B6YE57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SERBP1
gene id: 419612:SERBP1
uniprot id: A0A8B7KE35
uniprot id: A0A8B7KE41
uniprot id: A0A8B7KEC1
uniprot id: A0A8B7KGA1
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

419612:KCNJ15
gene id: 419612:KCNJ15
uniprot id: A0A8B8RVK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

419612:FPGS
gene id: 419612:FPGS
uniprot id: A0A8B8SXQ2
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

419612:KEG61 p11
gene id: 419612:KEG61_p11
uniprot id: A6YAR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

419612:ATP1A2
gene id: 419612:ATP1A2
uniprot id: A0A8B8RR50
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC102515525
gene id: 419612:LOC102515525
uniprot id: A0A8B8S088
uniprot id: A0A8B8S0I4
names: Subcellular Location Annotation
messages: Nucleus

419612:CPSF6
gene id: 419612:CPSF6
uniprot id: A0A8B8U3U7
uniprot id: A0A8B8U4K5
uniprot id: A0A8B8U4T4
uniprot id: A0A8B8U516
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

419612:FAH
gene id: 419612:FAH
uniprot id: A0A8B6YJT4
uniprot id: A0A8B7KD37
uniprot id: A0A8B8S602
names: Similarity
messages: Belongs to the FAH family.

419612:CDH5
gene id: 419612:CDH5
uniprot id: A0A8B6YC61
uniprot id: A0A8B8TKL3
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

419612:AKAP9
gene id: 419612:AKAP9
uniprot id: A0A8B6Y9K7
uniprot id: A0A8B7K584
uniprot id: A0A8B7K5C0
uniprot id: A0A8B7K7K3
uniprot id: A0A8B8TCD1
uniprot id: A0A8B8TCD2
uniprot id: A0A8B8TCF7
uniprot id: A0A8B8TCM1
names: Subcellular Location Annotation
messages: centrosome

419612:SLC5A1
gene id: 419612:SLC5A1
uniprot id: A0A8B6YFE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

419612:ARSI
gene id: 419612:ARSI
uniprot id: A0A8B6Y771
names: Similarity
messages: Belongs to the sulfatase family.

419612:MOK
gene id: 419612:MOK
uniprot id: A0A8B8T8L5
uniprot id: A0A8B8T8L7
uniprot id: A0A8B8T8L9
uniprot id: A0A8B8T935
uniprot id: A0A8B8T940
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:LOC102521056
gene id: 419612:LOC102521056
uniprot id: A0A8B6YAH4
names: Subcellular Location Annotation
messages: Secreted

419612:CA4
gene id: 419612:CA4
uniprot id: A0A8B8UI26
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

419612:S100A7
gene id: 419612:S100A7
uniprot id: A0A8B6YCF6
names: Similarity
messages: Belongs to the S-100 family.

419612:UBE2D2
gene id: 419612:UBE2D2
uniprot id: A0A8B8SS76
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:VAT1
gene id: 419612:VAT1
uniprot id: A0A8B8R7Y2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

419612:LOC116667349
gene id: 419612:LOC116667349
uniprot id: A0A8B8U0E7
names: Caution
names: Similarity
messages: Belongs to the spermadhesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:HMX2
gene id: 419612:HMX2
uniprot id: A0A8B8TWC7
uniprot id: A0A8B8TXE3
names: Subcellular Location Annotation
messages: Nucleus

419612:COG2
gene id: 419612:COG2
uniprot id: A0A8B8TZJ6
uniprot id: A0A8B8U0U8
names: Similarity
messages: Belongs to the COG2 family.

419612:KCNAB1
gene id: 419612:KCNAB1
uniprot id: A0A8B8TIN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

419612:TSFM
gene id: 419612:TSFM
uniprot id: A0A8B8U4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

419612:BOLA1
gene id: 419612:BOLA1
uniprot id: A0A8B7KB43
names: Similarity
messages: Belongs to the BolA/IbaG family.

419612:CHRDL2
gene id: 419612:CHRDL2
uniprot id: A0A8B6YCK2
names: Subcellular Location Annotation
messages: Secreted

419612:LOC116667506
gene id: 419612:LOC116667506
uniprot id: A0A8B8U0J3
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

419612:TNFAIP2
gene id: 419612:TNFAIP2
uniprot id: A0A8B8T972
names: Similarity
messages: Belongs to the SEC6 family.

419612:CENPL
gene id: 419612:CENPL
uniprot id: A0A8B6Y576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

419612:GJB2
gene id: 419612:GJB2
uniprot id: A0A8B8UDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

419612:SQSTM1
gene id: 419612:SQSTM1
uniprot id: A0A8B8RSY5
names: Subcellular Location Annotation
messages: Lysosome
messages: autophagosome

419612:UPF1
gene id: 419612:UPF1
uniprot id: A0A8B8RUN7
uniprot id: A0A8B8RUZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

419612:HABP4
gene id: 419612:HABP4
uniprot id: A0A8B8SU65
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

419612:THRA
gene id: 419612:THRA
uniprot id: A0A8B8RA25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

419612:ZIC4
gene id: 419612:ZIC4
uniprot id: A0A8B8TLE3
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

419612:PSME3IP1
gene id: 419612:PSME3IP1
uniprot id: A0A8B8TJ53
names: Subcellular Location Annotation
messages: Nucleus

419612:SLC28A2
gene id: 419612:SLC28A2
uniprot id: A0A8B6Y865
uniprot id: A0A8B8T4J1
uniprot id: A0A8B8T595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

419612:KRI1
gene id: 419612:KRI1
uniprot id: A0A8B8RVV4
uniprot id: A0A8B8RW56
names: Similarity
messages: Belongs to the KRI1 family.

419612:ZC3H15
gene id: 419612:ZC3H15
uniprot id: A0A8B6YJF1
names: Similarity
messages: Belongs to the ZC3H15/TMA46 family.

419612:INTS14
gene id: 419612:INTS14
uniprot id: A0A8B8T3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

419612:DYNLL1
gene id: 419612:DYNLL1
uniprot id: T0MDX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

419612:BORA
gene id: 419612:BORA
uniprot id: A0A8B6YQ46
uniprot id: A0A8B8UDW4
names: Similarity
messages: Belongs to the BORA family.

419612:SIX6
gene id: 419612:SIX6
uniprot id: A0A8B6YGB6
names: Subcellular Location Annotation
messages: Nucleus

419612:AIF1
gene id: 419612:AIF1
uniprot id: A0A8B6Y9V5
names: Subcellular Location Annotation
messages: ruffle membrane

419612:NTF3
gene id: 419612:NTF3
uniprot id: A0A8B8SFH8
uniprot id: A0A8B8SFI1
uniprot id: A0A8B8SGM9
uniprot id: A0A8B8SI47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

419612:RCL1
gene id: 419612:RCL1
uniprot id: A0A8B7KAV9
uniprot id: A0A8B7KAX8
uniprot id: A0A8B8SU33
uniprot id: A0A8B8SUA5
uniprot id: A0A8B8SUJ2
uniprot id: A0A8B8SUZ1
uniprot id: A0A8B8SVM9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.
messages: nucleolus

419612:TGFB3
gene id: 419612:TGFB3
uniprot id: A0A8B7KA10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

419612:LGI3
gene id: 419612:LGI3
uniprot id: A0A8B6YBT1
uniprot id: A0A8B8SB93
names: Subcellular Location Annotation
messages: Secreted

419612:DRD5
gene id: 419612:DRD5
uniprot id: A0A8B8UDS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:PSMC4
gene id: 419612:PSMC4
uniprot id: A0A8B6YD48
names: Similarity
messages: Belongs to the AAA ATPase family.

419612:DUOX1
gene id: 419612:DUOX1
uniprot id: A0A8B8T4H4
uniprot id: A0A8B8T4I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

419612:LOC102514263
gene id: 419612:LOC102514263
uniprot id: A0A8B8U0N2
uniprot id: A0A8B8U0P1
uniprot id: A0A8B8U106
uniprot id: A0A8B8U111
uniprot id: A0A8B8U1P7
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:LOC102523619
gene id: 419612:LOC102523619
uniprot id: A0A8B7KEG2
names: Similarity
messages: Belongs to the SPATA31 family.

419612:MSR1
gene id: 419612:MSR1
uniprot id: A0A8B8S2X5
uniprot id: A0A8B8S494
names: Subcellular Location Annotation
messages: Membrane

419612:XRN1
gene id: 419612:XRN1
uniprot id: A0A8B6YKL5
uniprot id: A0A8B8TMJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm

419612:TDP1
gene id: 419612:TDP1
uniprot id: A0A8B6YRB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

419612:SNX4
gene id: 419612:SNX4
uniprot id: A0A8B8T3B5
names: Similarity
messages: Belongs to the sorting nexin family.

419612:LOC102505092
gene id: 419612:LOC102505092
uniprot id: A0A8B8RBK6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

419612:SLC25A11
gene id: 419612:SLC25A11
uniprot id: A0A8B8UIW2
uniprot id: A0A8B8UJ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:LOC102513678
gene id: 419612:LOC102513678
uniprot id: A0A8B8TGR3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

419612:IL7
gene id: 419612:IL7
uniprot id: A0A8B6YHM9
uniprot id: A0A8B7KAQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-7/IL-9 family.
messages: Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis.
messages: Interacts with IL7R and CSF2RG.
messages: Secreted

419612:PIH1D2
gene id: 419612:PIH1D2
uniprot id: A0A8B6Y612
names: Similarity
messages: Belongs to the PIH1 family.

419612:FXYD1
gene id: 419612:FXYD1
uniprot id: A0A8B7K9Z2
uniprot id: A0A8B7KBP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the FXYD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: T-tubule
messages: caveola
messages: sarcolemma

419612:NODAL
gene id: 419612:NODAL
uniprot id: A0A8B7K7L4
names: Similarity
messages: Belongs to the TGF-beta family.

419612:CNOT6L
gene id: 419612:CNOT6L
uniprot id: A0A8B8R5I0
uniprot id: A0A8B8R5R9
uniprot id: A0A8B8R892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

419612:HINT1
gene id: 419612:HINT1
uniprot id: A0A8B8SQV6
names: Similarity
messages: Belongs to the HINT family.

419612:CELF2
gene id: 419612:CELF2
uniprot id: A0A8B8SII3
uniprot id: A0A8B8SII5
uniprot id: A0A8B8SII8
uniprot id: A0A8B8SJL7
uniprot id: A0A8B8SJW8
uniprot id: A0A8B8SKY5
uniprot id: A0A8B8SKZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

419612:SRPRA
gene id: 419612:SRPRA
uniprot id: A0A8B6YCN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:SYT17
gene id: 419612:SYT17
uniprot id: A0A8B8RHU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Membrane

419612:NKX1-1
gene id: 419612:NKX1-1
uniprot id: A0A8B8TXQ7
names: Subcellular Location Annotation
messages: Nucleus

419612:TBP
gene id: 419612:TBP
uniprot id: A0A8B6YNR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

419612:TMEM176A
gene id: 419612:TMEM176A
uniprot id: A0A8B7KFV8
names: Similarity
messages: Belongs to the TMEM176 family.

419612:CAMK1G
gene id: 419612:CAMK1G
uniprot id: A0A8B8RXN5
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:LOC102516729
gene id: 419612:LOC102516729
uniprot id: S9XLP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:BTC
gene id: 419612:BTC
uniprot id: A0A8B8R9G2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:HSPB8
gene id: 419612:HSPB8
uniprot id: A0A8B8SCZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Displays temperature-dependent chaperone activity.
messages: Nucleus

419612:ABCB1
gene id: 419612:ABCB1
uniprot id: A0A8B8TCT1
names: Subcellular Location Annotation
messages: Membrane

419612:CNDP1
gene id: 419612:CNDP1
uniprot id: A0A8B8S7Z5
uniprot id: A0A8B8S7Z8
uniprot id: A0A8B8S9E9
uniprot id: A0A8B8SA69
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

419612:LAMB3
gene id: 419612:LAMB3
uniprot id: A0A8B7K792
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:RRAGC
gene id: 419612:RRAGC
uniprot id: A0A8B8U5B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

419612:QRFP
gene id: 419612:QRFP
uniprot id: A0A8B6YD91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

419612:TMPRSS15
gene id: 419612:TMPRSS15
uniprot id: A0A8B6YF34
uniprot id: A0A8B6YIT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMBT1 family.
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.

419612:PRR20G
gene id: 419612:PRR20G
uniprot id: A0A8B8RBH6
names: Similarity
messages: Belongs to the PRR20 family.

419612:REN
gene id: 419612:REN
uniprot id: A0A8B6YD66
uniprot id: A0A8B6YDK2
names: Similarity
messages: Belongs to the peptidase A1 family.

419612:LOC116663368
gene id: 419612:LOC116663368
uniprot id: A0A8B8SZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FIGN
gene id: 419612:FIGN
uniprot id: A0A8B8SZN1
uniprot id: A0A8B8T0M1
uniprot id: A0A8B8T0M6
uniprot id: S9WWN3
names: Similarity
messages: Belongs to the AAA ATPase family.

419612:CORT
gene id: 419612:CORT
uniprot id: A0A8B6YB17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

419612:NOS3
gene id: 419612:NOS3
uniprot id: A0A8B8T9W8
uniprot id: A0A8B8TA06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

419612:SKIL
gene id: 419612:SKIL
uniprot id: A0A8B8TDM1
names: Similarity
messages: Belongs to the SKI family.

419612:DHX29
gene id: 419612:DHX29
uniprot id: A0A8B6YGH6
uniprot id: A0A8B8SE94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC) that contains at least Met-tRNA, EIF1, EIF1A (EIF1AX or EIF1AY), EIF2S1, EIF2S2, EIF2S3, EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L, EIF3M, DHX29 and the 40S ribosomal subunit.

419612:CDK5R2
gene id: 419612:CDK5R2
uniprot id: A0A8B8T1L5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

419612:HCFC2
gene id: 419612:HCFC2
uniprot id: A0A8B8U520
names: Subcellular Location Annotation
messages: Nucleus

419612:C30H18orf25
gene id: 419612:C30H18orf25
uniprot id: A0A8B8S8P5
uniprot id: A0A8B8SA45
uniprot id: A0A8B8SAY9
names: Subcellular Location Annotation
messages: Nucleus

419612:TMEM165
gene id: 419612:TMEM165
uniprot id: A0A8B8UGR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

419612:IMP3
gene id: 419612:IMP3
uniprot id: A0A8B8S4C6
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

419612:LOC102504681
gene id: 419612:LOC102504681
uniprot id: A0A8B8TNN8
names: Similarity
messages: Belongs to the PRR23 family.

419612:OAT
gene id: 419612:OAT
uniprot id: A0A8B8TXN7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

419612:RPL29
gene id: 419612:RPL29
uniprot id: A0A8B7K6W3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

419612:KCNQ2
gene id: 419612:KCNQ2
uniprot id: A0A8B8RHP3
uniprot id: A0A8B8RHP5
uniprot id: A0A8B8RHX1
uniprot id: A0A8B8RJK9
uniprot id: A0A8B8RK04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:LDB1
gene id: 419612:LDB1
uniprot id: A0A8B6YF26
uniprot id: A0A8B8TXA1
uniprot id: A0A8B8TYM5
names: Similarity
messages: Belongs to the LDB family.

419612:LOC102512016
gene id: 419612:LOC102512016
uniprot id: A0A8B6YAE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ALKAL2
gene id: 419612:ALKAL2
uniprot id: A0A8B8UER2
uniprot id: A0A8B8UET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

419612:LOC102503473
gene id: 419612:LOC102503473
uniprot id: A0A8B8SRN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:SPESP1
gene id: 419612:SPESP1
uniprot id: A0A8B8S3V1
uniprot id: A0A8B8S5D6
uniprot id: A0A8B8S5R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPESP1 family.
messages: Involved in fertilization ability of sperm.
messages: acrosome

419612:KARS1
gene id: 419612:KARS1
uniprot id: A0A8B7KHP4
uniprot id: A0A8B8TLI2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

419612:PRDX2
gene id: 419612:PRDX2
uniprot id: S9XCE6
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

419612:AHDC1
gene id: 419612:AHDC1
uniprot id: A0A8B8UAA5
names: Subcellular Location Annotation
messages: Nucleus

419612:SLC17A4
gene id: 419612:SLC17A4
uniprot id: A0A8B6YDG9
uniprot id: A0A8B8RKP1
uniprot id: A0A8B8RKP4
uniprot id: A0A8B8RMF7
uniprot id: A0A8B8RMW9
names: Subcellular Location Annotation
messages: Membrane

419612:PFAS
gene id: 419612:PFAS
uniprot id: A0A8B7K4S5
uniprot id: A0A8B8UJB9
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

419612:JUP
gene id: 419612:JUP
uniprot id: A0A8B8UHY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

419612:IRF1
gene id: 419612:IRF1
uniprot id: A0A8B6YER5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

419612:COQ6
gene id: 419612:COQ6
uniprot id: A0A8B8T7K4
uniprot id: A0A8B8T852
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

419612:HRH4
gene id: 419612:HRH4
uniprot id: A0A8B6YKF3
uniprot id: A0A8B8RZ44
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:BOK
gene id: 419612:BOK
uniprot id: A0A8B8T3F0
uniprot id: A0A8B8T3V6
names: Similarity
messages: Belongs to the Bcl-2 family.

419612:LOC102524496
gene id: 419612:LOC102524496
uniprot id: A0A8B8SHK1
names: Similarity
messages: Belongs to the 14-3-3 family.

419612:MC2R
gene id: 419612:MC2R
uniprot id: S9XWD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

419612:MVD
gene id: 419612:MVD
uniprot id: A0A8B8RT83
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

419612:LOC102513357
gene id: 419612:LOC102513357
uniprot id: A0A8B8SYY0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

419612:MYMK
gene id: 419612:MYMK
uniprot id: A0A8B8SXU8
uniprot id: A0A8B8SYM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

419612:LOC102506250
gene id: 419612:LOC102506250
uniprot id: S9XH29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PAQR9
gene id: 419612:PAQR9
uniprot id: A0A8B8TMA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

419612:SLC12A7
gene id: 419612:SLC12A7
uniprot id: A0A8B8S4Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

419612:PIGB
gene id: 419612:PIGB
uniprot id: A0A8B6YCD5
uniprot id: A0A8B8T4F6
uniprot id: A0A8B8T4V5
uniprot id: A0A8B8T4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:LOC102506282
gene id: 419612:LOC102506282
uniprot id: A0A8B8TWM8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:KDELR3
gene id: 419612:KDELR3
uniprot id: A0A8B6Y6N0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:PRIM2
gene id: 419612:PRIM2
uniprot id: A0A8B6YP86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

419612:SNPH
gene id: 419612:SNPH
uniprot id: A0A8B8RIV6
uniprot id: A0A8B8RL46
names: Subcellular Location Annotation
messages: Membrane

419612:IP6K1
gene id: 419612:IP6K1
uniprot id: A0A8B8R8S9
uniprot id: A0A8B8RAX1
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

419612:AHSA1
gene id: 419612:AHSA1
uniprot id: A0A8B6YFE6
names: Similarity
messages: Belongs to the AHA1 family.

419612:CHST8
gene id: 419612:CHST8
uniprot id: A0A8B8TIN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:IFNGR1
gene id: 419612:IFNGR1
uniprot id: A0A8B7KCR7
uniprot id: A0A8B8TF92
uniprot id: A0A8B8TFC4
names: Similarity
messages: Belongs to the type II cytokine receptor family.

419612:SKA2
gene id: 419612:SKA2
uniprot id: A0A8B6YCE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

419612:VPS33B
gene id: 419612:VPS33B
uniprot id: A0A8B6YP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

419612:LOC102518805
gene id: 419612:LOC102518805
uniprot id: A0A8B8SCM6
uniprot id: A0A8B8SCN0
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

419612:USP5
gene id: 419612:USP5
uniprot id: A0A8B6YC72
uniprot id: S9XGT9
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

419612:LOC102518984
gene id: 419612:LOC102518984
uniprot id: A0A8B6YNC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102522851
gene id: 419612:LOC102522851
uniprot id: A0A8B6YAQ3
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

419612:TM9SF2
gene id: 419612:TM9SF2
uniprot id: A0A8B6YPI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

419612:TBCD
gene id: 419612:TBCD
uniprot id: A0A8B8UKA9
names: Similarity
messages: Belongs to the TBCD family.

419612:LOC116666682
gene id: 419612:LOC116666682
uniprot id: A0A8B8TVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ID1
gene id: 419612:ID1
uniprot id: A0A8B8RKW4
uniprot id: A0A8B8RLC1
names: Subcellular Location Annotation
messages: Nucleus

419612:SEMA6D
gene id: 419612:SEMA6D
uniprot id: A0A8B6YLY0
uniprot id: A0A8B8T4F5
uniprot id: A0A8B8T4G3
uniprot id: A0A8B8T4G7
uniprot id: A0A8B8T4R9
uniprot id: A0A8B8T4S4
uniprot id: A0A8B8T565
uniprot id: A0A8B8T598
uniprot id: A0A8B8T5A1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102524409
gene id: 419612:LOC102524409
uniprot id: A0A8B7KI29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:NNT
gene id: 419612:NNT
uniprot id: A0A8B8SCY2
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

419612:LOC102510891
gene id: 419612:LOC102510891
uniprot id: S9WE35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

419612:PAQR3
gene id: 419612:PAQR3
uniprot id: A0A8B7KDL5
uniprot id: A0A8B7KDV8
uniprot id: A0A8B7KFR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

419612:MRPS15
gene id: 419612:MRPS15
uniprot id: A0A8B6YH83
uniprot id: A0A8B7KBU4
uniprot id: A0A8B8UC05
uniprot id: A0A8B8UC55
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

419612:TMEM231
gene id: 419612:TMEM231
uniprot id: A0A8B6YN81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

419612:HIRIP3
gene id: 419612:HIRIP3
uniprot id: A0A8B7K7V2
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102505609
gene id: 419612:LOC102505609
uniprot id: A0A8B8U449
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOXL4
gene id: 419612:LOXL4
uniprot id: A0A8B8TXJ8
uniprot id: A0A8B8TXK0
uniprot id: A0A8B8TXK2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

419612:MARCO
gene id: 419612:MARCO
uniprot id: A0A8B7KGK7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC102507633
gene id: 419612:LOC102507633
uniprot id: A0A8B6YJS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:OSBPL9
gene id: 419612:OSBPL9
uniprot id: A0A8B8U791
names: Similarity
messages: Belongs to the OSBP family.

419612:ALDH1A1
gene id: 419612:ALDH1A1
uniprot id: A0A8B6YS11
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

419612:DHPS
gene id: 419612:DHPS
uniprot id: A0A8B6YDQ7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

419612:GADL1
gene id: 419612:GADL1
uniprot id: A0A8B8RBA6
uniprot id: A0A8B8RDX8
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

419612:SLC6A17
gene id: 419612:SLC6A17
uniprot id: A0A8B8TLQ5
uniprot id: A0A8B8TM41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

419612:IRF2BPL
gene id: 419612:IRF2BPL
uniprot id: A0A8B8T7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

419612:TUBG1
gene id: 419612:TUBG1
uniprot id: A0A8B8R558
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

419612:MED31
gene id: 419612:MED31
uniprot id: S9XEP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

419612:ATP11C
gene id: 419612:ATP11C
uniprot id: A0A8B8SJH4
uniprot id: A0A8B8SJI0
uniprot id: A0A8B8SKL4
uniprot id: A0A8B8SKM0
uniprot id: A0A8B8SKX7
uniprot id: A0A8B8SLW8
uniprot id: A0A8B8SLX3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC102519854
gene id: 419612:LOC102519854
uniprot id: A0A8B6YBJ6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RASGRP3
gene id: 419612:RASGRP3
uniprot id: A0A8B8UF53
uniprot id: A0A8B8UF58
uniprot id: A0A8B8UFV1
names: Similarity
messages: Belongs to the RASGRP family.

419612:ABCC6
gene id: 419612:ABCC6
uniprot id: A0A8B6YAS1
uniprot id: A0A8B7K6L1
uniprot id: A0A8B8RID7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

419612:LDLRAD3
gene id: 419612:LDLRAD3
uniprot id: A0A8B8TQ07
uniprot id: A0A8B8TQ12
uniprot id: A0A8B8TQ18
uniprot id: A0A8B8TQ25
uniprot id: A0A8B8TQR8
uniprot id: A0A8B8TR70
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:AP3S1
gene id: 419612:AP3S1
uniprot id: A0A8B8SQI2
uniprot id: A0A8B8SQJ5
uniprot id: A0A8B8SSH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

419612:DOCK7
gene id: 419612:DOCK7
uniprot id: A0A8B8U6W4
uniprot id: A0A8B8U6W5
uniprot id: A0A8B8U6X0
uniprot id: A0A8B8U6X1
uniprot id: A0A8B8U6X6
uniprot id: A0A8B8U7S7
uniprot id: A0A8B8U7T4
uniprot id: A0A8B8U7W6
uniprot id: A0A8B8U7Y6
uniprot id: A0A8B8U7Z4
uniprot id: A0A8B8U7Z9
names: Similarity
messages: Belongs to the DOCK family.

419612:ANO7
gene id: 419612:ANO7
uniprot id: A0A8B8SYF9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:EEF1G
gene id: 419612:EEF1G
uniprot id: A0A8B6YGR4
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

419612:FRK
gene id: 419612:FRK
uniprot id: A0A8B6YMY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

419612:CLGN
gene id: 419612:CLGN
uniprot id: A0A8B8RPC3
names: Similarity
messages: Belongs to the calreticulin family.

419612:NUPR2
gene id: 419612:NUPR2
uniprot id: A0A8B8RGM9
names: Similarity
messages: Belongs to the NUPR family.

419612:SLC25A29
gene id: 419612:SLC25A29
uniprot id: A0A8B8T8F0
uniprot id: A0A8B8T8F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:RTRAF
gene id: 419612:RTRAF
uniprot id: A0A8B6YMN3
names: Similarity
messages: Belongs to the RTRAF family.

419612:LOC116660183
gene id: 419612:LOC116660183
uniprot id: A0A8B8S569
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

419612:MRPL58
gene id: 419612:MRPL58
uniprot id: A0A8B8R419
uniprot id: A0A8B8R489
names: Subcellular Location Annotation
messages: Mitochondrion

419612:LOC102520226
gene id: 419612:LOC102520226
uniprot id: A0A8B6Y739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

419612:NNAT
gene id: 419612:NNAT
uniprot id: A0A8B6YKA6
uniprot id: A0A8B6YMS7
uniprot id: A0A8B8RK05
names: Similarity
messages: Belongs to the neuronatin family.

419612:TACC2
gene id: 419612:TACC2
uniprot id: A0A8B8TXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

419612:NCF2
gene id: 419612:NCF2
uniprot id: A0A8B8RND9
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

419612:CLDN17
gene id: 419612:CLDN17
uniprot id: A0A8B6YQF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

419612:SENP1
gene id: 419612:SENP1
uniprot id: A0A8B8U1Y8
uniprot id: A0A8B8U1Z0
uniprot id: A0A8B8U2Z4
uniprot id: A0A8B8U375
names: Similarity
messages: Belongs to the peptidase C48 family.

419612:LOC102507340
gene id: 419612:LOC102507340
uniprot id: A0A8B6YGJ2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC116666849
gene id: 419612:LOC116666849
uniprot id: A0A8B8TX67
names: Subcellular Location Annotation
messages: Membrane

419612:CLEC16A
gene id: 419612:CLEC16A
uniprot id: A0A8B8RFE2
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

419612:FAM124B
gene id: 419612:FAM124B
uniprot id: A0A8B6YDZ4
names: Similarity
messages: Belongs to the FAM124 family.

419612:LOC102514398
gene id: 419612:LOC102514398
uniprot id: A0A8B6YG95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102516748
gene id: 419612:LOC102516748
uniprot id: A0A8B7KEX4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CCDC22
gene id: 419612:CCDC22
uniprot id: A0A8B8SMQ9
names: Similarity
messages: Belongs to the CCDC22 family.

419612:LOC102524207
gene id: 419612:LOC102524207
uniprot id: A0A8B8T5C8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:FLT4
gene id: 419612:FLT4
uniprot id: A0A8B8RS24
uniprot id: A0A8B8RSV8
uniprot id: A0A8B8RTP3
uniprot id: A0A8B8RU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

419612:ADGRA1
gene id: 419612:ADGRA1
uniprot id: A0A8B8TW26
uniprot id: A0A8B8TXF2
names: Subcellular Location Annotation
messages: Membrane

419612:SLC1A5
gene id: 419612:SLC1A5
uniprot id: A0A8B7K3X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

419612:DRD1
gene id: 419612:DRD1
uniprot id: A0A8B8RSN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
messages: Membrane
messages: dendritic spine

419612:PPP2R5B
gene id: 419612:PPP2R5B
uniprot id: A0A8B8TUR9
uniprot id: T0MET2
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

419612:TFEB
gene id: 419612:TFEB
uniprot id: A0A8B8RNN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

419612:SPNS3
gene id: 419612:SPNS3
uniprot id: A0A8B6Y4I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

419612:CR1
gene id: 419612:CR1
uniprot id: A0A8B8RYE4
uniprot id: A0A8B8S032
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:RANBP9
gene id: 419612:RANBP9
uniprot id: A0A8B8RKD1
uniprot id: A0A8B8RKN7
names: Similarity
messages: Belongs to the RANBP9/10 family.

419612:LOC116657404
gene id: 419612:LOC116657404
uniprot id: A0A8B8RBI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

419612:LOC102512119
gene id: 419612:LOC102512119
uniprot id: A0A8B8TTD6
names: Subcellular Location Annotation
messages: Membrane

419612:UBE3A
gene id: 419612:UBE3A
uniprot id: A0A8B8S3V3
uniprot id: A0A8B8S562
uniprot id: A0A8B8S5E6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

419612:RPS6KA3
gene id: 419612:RPS6KA3
uniprot id: A0A8B8SMY0
uniprot id: A0A8B8SNW9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

419612:LAMA5
gene id: 419612:LAMA5
uniprot id: A0A8B8RHH1
uniprot id: A0A8B8RHP7
uniprot id: A0A8B8RJD7
uniprot id: A0A8B8RJT5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

419612:LOC102517377
gene id: 419612:LOC102517377
uniprot id: A0A8B7K9H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC116663077
gene id: 419612:LOC116663077
uniprot id: A0A8B8SVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

419612:PIEZO2
gene id: 419612:PIEZO2
uniprot id: A0A8B8RZX6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:GFAP
gene id: 419612:GFAP
uniprot id: A0A8B7K6C0
uniprot id: A0A8B8R5K3
uniprot id: A0A8B8R7S3
names: Similarity
messages: Belongs to the intermediate filament family.

419612:RPS27L
gene id: 419612:RPS27L
uniprot id: A0A8B6Y9E8
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

419612:FYN
gene id: 419612:FYN
uniprot id: A0A8B8TEE6
uniprot id: A0A8B8TEF2
uniprot id: A0A8B8TEJ5
uniprot id: A0A8B8TFR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

419612:ST3GAL6
gene id: 419612:ST3GAL6
uniprot id: A0A8B8TUB6
uniprot id: A0A8B8TUC3
uniprot id: A0A8B8TUC9
uniprot id: A0A8B8TVQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

419612:RPRD2
gene id: 419612:RPRD2
uniprot id: A0A8B6YH66
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

419612:ENTPD5
gene id: 419612:ENTPD5
uniprot id: A0A8B8T7K9
uniprot id: A0A8B8T7L0
uniprot id: A0A8B8T7T0
uniprot id: A0A8B8T858
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

419612:LOC102505359
gene id: 419612:LOC102505359
uniprot id: A0A8B7KIQ8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ROCK2
gene id: 419612:ROCK2
uniprot id: A0A8B8UEB2
uniprot id: A0A8B8UEB5
uniprot id: A0A8B8UEB8
uniprot id: A0A8B8UF18
uniprot id: A0A8B8UF24
uniprot id: A0A8B8UF38
uniprot id: A0A8B8UF43
uniprot id: A0A8B8UFQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus
messages: centrosome

419612:ADAMTS10
gene id: 419612:ADAMTS10
uniprot id: A0A8B8RXL9
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102520813
gene id: 419612:LOC102520813
uniprot id: A0A8B8RVM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:OLFM1
gene id: 419612:OLFM1
uniprot id: A0A8B8SXZ5
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

419612:PRKRA
gene id: 419612:PRKRA
uniprot id: A0A8B8T0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRKRA family.
messages: perinuclear region

419612:TSPAN3
gene id: 419612:TSPAN3
uniprot id: A0A8B8S4Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:PTP4A1
gene id: 419612:PTP4A1
uniprot id: A0A8B8TDL7
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

419612:GGA2
gene id: 419612:GGA2
uniprot id: A0A8B6YN02
uniprot id: A0A8B7KHH6
uniprot id: A0A8B8RI27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

419612:CAPN13
gene id: 419612:CAPN13
uniprot id: A0A8B8UFR8
names: Similarity
messages: Belongs to the peptidase C2 family.

419612:LOC102506660
gene id: 419612:LOC102506660
uniprot id: A0A8B6YI02
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

419612:ABCB8
gene id: 419612:ABCB8
uniprot id: A0A8B6YM13
uniprot id: A0A8B7KF02
names: Subcellular Location Annotation
messages: Membrane

419612:ELOA
gene id: 419612:ELOA
uniprot id: A0A8B8U9S8
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102523416
gene id: 419612:LOC102523416
uniprot id: A0A8B8TD17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

419612:LOC102515287
gene id: 419612:LOC102515287
uniprot id: A0A8B8TS47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:XKR4
gene id: 419612:XKR4
uniprot id: A0A8B6YMJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

419612:LOC102517616
gene id: 419612:LOC102517616
uniprot id: S9WZ75
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

419612:PPIA
gene id: 419612:PPIA
uniprot id: A0A8B8TDA9
uniprot id: A0A8B8TEK7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

419612:DUSP27
gene id: 419612:DUSP27
uniprot id: A0A8B6YNN8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

419612:NKX3-2
gene id: 419612:NKX3-2
uniprot id: A0A8B8U6Z0
uniprot id: A0A8B8U6Z4
names: Subcellular Location Annotation
messages: Nucleus

419612:FZD4
gene id: 419612:FZD4
uniprot id: A0A8B7KF71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

419612:AADACL2
gene id: 419612:AADACL2
uniprot id: A0A8B6YJJ5
uniprot id: A0A8B8TIR3
uniprot id: A0A8B8TIU7
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

419612:TDRD9
gene id: 419612:TDRD9
uniprot id: A0A8B8T8W3
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

419612:TOP1
gene id: 419612:TOP1
uniprot id: A0A8B8RK45
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

419612:CXCL8
gene id: 419612:CXCL8
uniprot id: A0A8B6YJ24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

419612:TAS2R16
gene id: 419612:TAS2R16
uniprot id: A0A8B7K9B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

419612:ITM2C
gene id: 419612:ITM2C
uniprot id: A0A8B8T2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

419612:FFAR1
gene id: 419612:FFAR1
uniprot id: A0A8B6YGA9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:LOC106729282
gene id: 419612:LOC106729282
uniprot id: A0A8B8RPN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:EIF3G
gene id: 419612:EIF3G
uniprot id: A0A8B6YAZ9
uniprot id: A0A8B7K6E4
uniprot id: A0A8B7K8P3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of FRAP1 and RAPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts (via C-terminus) with AIFM1 (via N-terminus).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit can bind 18S rRNA.
messages: perinuclear region

419612:LOC102505799
gene id: 419612:LOC102505799
uniprot id: A0A8B8U1N5
names: Similarity
messages: Belongs to the apolipoprotein L family.

419612:CLU
gene id: 419612:CLU
uniprot id: A0A8B8S9C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antiparallel disulfide-linked heterodimer of an alpha chain and a beta chain. Self-associates and forms higher oligomers.
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.
messages: Membrane
messages: Microsome
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol
messages: perinuclear region

419612:SLC26A10
gene id: 419612:SLC26A10
uniprot id: A0A8B8U4K9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:KCNK9
gene id: 419612:KCNK9
uniprot id: A0A8B8S1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

419612:AP1M2
gene id: 419612:AP1M2
uniprot id: A0A8B8RVE8
uniprot id: T0MIK4
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

419612:CCNI
gene id: 419612:CCNI
uniprot id: A0A8B8R5U7
uniprot id: A0A8B8R8J8
names: Similarity
messages: Belongs to the cyclin family.

419612:TIMP1
gene id: 419612:TIMP1
uniprot id: A0A8B8SMS2
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

419612:PELO
gene id: 419612:PELO
uniprot id: A0A8B8SCB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.
messages: Cytoplasm

419612:GAL
gene id: 419612:GAL
uniprot id: A0A8B8TVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

419612:LOC102519489
gene id: 419612:LOC102519489
uniprot id: A0A8B8SJE3
names: Similarity
messages: Belongs to the intermediate filament family.

419612:LOC102507905
gene id: 419612:LOC102507905
uniprot id: A0A8B8TAD9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

419612:LOC116656617
gene id: 419612:LOC116656617
uniprot id: A0A8B6YPM1
uniprot id: A0A8B8TP80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

419612:NDST1
gene id: 419612:NDST1
uniprot id: A0A8B8STZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

419612:ATP8B1
gene id: 419612:ATP8B1
uniprot id: A0A8B8SAT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

419612:LOC102513512
gene id: 419612:LOC102513512
uniprot id: A0A8B8U5D1
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

419612:ZNF280A
gene id: 419612:ZNF280A
uniprot id: A0A8B8SBD8
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

419612:FXYD7
gene id: 419612:FXYD7
uniprot id: A0A8B6YFC8
uniprot id: A0A8B7KAE1
uniprot id: A0A8B8TP42
uniprot id: A0A8B8TP49
uniprot id: A0A8B8TP51
uniprot id: A0A8B8TP53
uniprot id: A0A8B8TP54
uniprot id: A0A8B8TPS7
uniprot id: A0A8B8TPT2
uniprot id: A0A8B8TQA7
names: Similarity
messages: Belongs to the FXYD family.

419612:CHRNE
gene id: 419612:CHRNE
uniprot id: A0A8B8UIQ6
uniprot id: A0A8B8UIU8
uniprot id: A0A8B8UJ66
uniprot id: A0A8B8UJ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:KDM5C
gene id: 419612:KDM5C
uniprot id: A0A8B8SN60
uniprot id: A0A8B8SN62
uniprot id: A0A8B8SN65
uniprot id: A0A8B8SP50
uniprot id: A0A8B8SPG6
uniprot id: A0A8B8SPH0
uniprot id: A0A8B8SQC4
uniprot id: A0A8B8SQC8
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

419612:HSF1
gene id: 419612:HSF1
uniprot id: A0A8B8RZS1
uniprot id: A0A8B8RZT2
uniprot id: A0A8B8S142
uniprot id: A0A8B8S1B9
uniprot id: A0A8B8S1D9
uniprot id: A0A8B8S1E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

419612:TBXA2R
gene id: 419612:TBXA2R
uniprot id: A0A8B6YEH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:GRN
gene id: 419612:GRN
uniprot id: A0A8B6Y945
uniprot id: A0A8B8R5I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

419612:ROS1
gene id: 419612:ROS1
uniprot id: A0A8B8TEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

419612:PDE2A
gene id: 419612:PDE2A
uniprot id: A0A8B8TSC8
uniprot id: A0A8B8TT96
uniprot id: A0A8B8TTG1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

419612:MSRB1
gene id: 419612:MSRB1
uniprot id: A0A8B6Y6C1
uniprot id: A0A8B8RDI9
uniprot id: A0A8B8RDJ2
uniprot id: A0A8B8RDP7
uniprot id: A0A8B8RDQ2
uniprot id: A0A8B8RG30
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.

419612:GRAMD1A
gene id: 419612:GRAMD1A
uniprot id: A0A8B8TNV8
uniprot id: A0A8B8TNW1
uniprot id: A0A8B8TPH5
uniprot id: A0A8B8TPI0
uniprot id: A0A8B8TQ19
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:EIF5
gene id: 419612:EIF5
uniprot id: S9XJ72
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

419612:TCIRG1
gene id: 419612:TCIRG1
uniprot id: A0A8B7K9I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

419612:VPS33A
gene id: 419612:VPS33A
uniprot id: A0A8B6Y976
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

419612:CNR1
gene id: 419612:CNR1
uniprot id: S9X4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Signaling typically involves reduction in cyclic AMP.
messages: Interacts (via C-terminus) with CNRIP1.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

419612:SLC44A5
gene id: 419612:SLC44A5
uniprot id: A0A8B8U7B8
uniprot id: A0A8B8U863
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

419612:ACAP3
gene id: 419612:ACAP3
uniprot id: A0A8B8U855
uniprot id: A0A8B8U956
uniprot id: A0A8B8U9A0
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

419612:PLB1
gene id: 419612:PLB1
uniprot id: A0A8B8UF00
uniprot id: A0A8B8UFP5
uniprot id: A0A8B8UFR4
uniprot id: A0A8B8UGD9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily.
messages: Cell membrane
messages: Membrane

419612:RFX3
gene id: 419612:RFX3
uniprot id: A0A8B8SU59
uniprot id: A0A8B8SVQ3
names: Subcellular Location Annotation
messages: Nucleus

419612:DDX59
gene id: 419612:DDX59
uniprot id: A0A8B8RZE7
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

419612:SUSD1
gene id: 419612:SUSD1
uniprot id: A0A8B8SVG6
uniprot id: A0A8B8SVH5
uniprot id: A0A8B8SVS0
uniprot id: A0A8B8SW83
uniprot id: A0A8B8SW88
uniprot id: A0A8B8SWV9
uniprot id: A0A8B8SWW3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:PWWP3A
gene id: 419612:PWWP3A
uniprot id: A0A8B8RXG9
names: Similarity
messages: Belongs to the PWWP3A family.

419612:MPP6
gene id: 419612:MPP6
uniprot id: A0A8B8TBW4
uniprot id: A0A8B8TC01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

419612:LOC102517614
gene id: 419612:LOC102517614
uniprot id: A0A8B6YBY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MACF1
gene id: 419612:MACF1
uniprot id: A0A8B7KAY8
names: Subcellular Location Annotation
messages: cytoskeleton

419612:LOC116661877
gene id: 419612:LOC116661877
uniprot id: A0A8B8SK29
names: Similarity
messages: Belongs to the PRAME family.

419612:PTGIS
gene id: 419612:PTGIS
uniprot id: A0A8B8RH04
uniprot id: A0A8B8RIY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).
messages: Endoplasmic reticulum membrane

419612:HIP1
gene id: 419612:HIP1
uniprot id: A0A8B6YCE7
uniprot id: A0A8B8RBV6
uniprot id: A0A8B8RBV8
uniprot id: A0A8B8REG6
names: Similarity
messages: Belongs to the SLA2 family.

419612:SEMA4F
gene id: 419612:SEMA4F
uniprot id: A0A8B8UGX0
uniprot id: A0A8B8UHI1
uniprot id: A0A8B8UHI6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:GJA9
gene id: 419612:GJA9
uniprot id: A0A8B8U5B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

419612:KDM5B
gene id: 419612:KDM5B
uniprot id: A0A8B8RYJ6
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

419612:TNFAIP6
gene id: 419612:TNFAIP6
uniprot id: A0A8B6YA73
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:DBX2
gene id: 419612:DBX2
uniprot id: A0A8B8U3J3
names: Subcellular Location Annotation
messages: Nucleus

419612:CMC1
gene id: 419612:CMC1
uniprot id: A0A8B8RBD5
uniprot id: A0A8B8RBD7
uniprot id: A0A8B8RDH1
uniprot id: A0A8B8RE05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

419612:LOC102512646
gene id: 419612:LOC102512646
uniprot id: A0A8B6YAE6
uniprot id: A0A8B8RPT0
uniprot id: A0A8B8RQB0
uniprot id: A0A8B8RRU4
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

419612:CCDC43
gene id: 419612:CCDC43
uniprot id: A0A8B6Y6T2
uniprot id: A0A8B7K6Q8
uniprot id: A0A8B8R5R4
names: Similarity
messages: Belongs to the CCDC43 family.

419612:RORB
gene id: 419612:RORB
uniprot id: A0A8B8SVZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

419612:HBM
gene id: 419612:HBM
uniprot id: S9XCL6
names: Similarity
messages: Belongs to the globin family.

419612:INTS11
gene id: 419612:INTS11
uniprot id: A0A8B8U864
uniprot id: A0A8B8U865
uniprot id: A0A8B8U869
uniprot id: A0A8B8U911
uniprot id: A0A8B8U916
uniprot id: A0A8B8U9B1
uniprot id: A0A8B8U9B8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, INTS11/CPSF3L and INTS12.
messages: Nucleus

419612:UBP1
gene id: 419612:UBP1
uniprot id: A0A8B8RDB7
uniprot id: A0A8B8RDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

419612:RIPPLY1
gene id: 419612:RIPPLY1
uniprot id: A0A8B6YNI8
uniprot id: A0A8B8SLC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

419612:LOC102518577
gene id: 419612:LOC102518577
uniprot id: S9XFU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102510026
gene id: 419612:LOC102510026
uniprot id: A0A8B8SFX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RPL11
gene id: 419612:RPL11
uniprot id: A0A8B6YBQ0
uniprot id: A0A8B7K6N1
uniprot id: A0A8B8UB17
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

419612:ME1
gene id: 419612:ME1
uniprot id: A0A8B8TE06
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

419612:LOC102505490
gene id: 419612:LOC102505490
uniprot id: A0A8B8R736
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.

419612:LOC116661968
gene id: 419612:LOC116661968
uniprot id: A0A8B8SKX9
names: Similarity
messages: Belongs to the SPT20 family.

419612:ERG28
gene id: 419612:ERG28
uniprot id: A0A8B6YJ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:STRN
gene id: 419612:STRN
uniprot id: A0A8B8UF55
uniprot id: A0A8B8UFX5
uniprot id: A0A8B8UGK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

419612:UTP15
gene id: 419612:UTP15
uniprot id: A0A8B6Y8G6
names: Subcellular Location Annotation
messages: nucleolus

419612:LOC106728422
gene id: 419612:LOC106728422
uniprot id: A0A8B7KCV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:IL4
gene id: 419612:IL4
uniprot id: A0A8B6YAV2
uniprot id: A0A8B8SR12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-4/IL-13 family.
messages: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
messages: Secreted

419612:ARHGDIG
gene id: 419612:ARHGDIG
uniprot id: A0A8B8RHM0
names: Similarity
messages: Belongs to the Rho GDI family.

419612:MAN1B1
gene id: 419612:MAN1B1
uniprot id: A0A8B8SXU0
uniprot id: A0A8B8SXX5
uniprot id: A0A8B8SYD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

419612:LOC106730764
gene id: 419612:LOC106730764
uniprot id: A0A8B8RFP3
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102512910
gene id: 419612:LOC102512910
uniprot id: A0A8B6YBX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

419612:PIM1
gene id: 419612:PIM1
uniprot id: A0A8B8RLQ7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

419612:TMEM132D
gene id: 419612:TMEM132D
uniprot id: A0A8B8SCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

419612:NPRL2
gene id: 419612:NPRL2
uniprot id: A0A8B8RAR3
uniprot id: A0A8B8RBE8
names: Similarity
messages: Belongs to the NPR2 family.

419612:HS3ST5
gene id: 419612:HS3ST5
uniprot id: A0A8B8TEH2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

419612:NKAIN1
gene id: 419612:NKAIN1
uniprot id: A0A8B8UAL5
uniprot id: A0A8B8UBH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

419612:UBE2K
gene id: 419612:UBE2K
uniprot id: A0A8B8UBL5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:ALPL
gene id: 419612:ALPL
uniprot id: A0A8B6YIM9
uniprot id: A0A8B7KCM2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

419612:LOC116659650
gene id: 419612:LOC116659650
uniprot id: A0A8B8S129
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

419612:RRAGB
gene id: 419612:RRAGB
uniprot id: A0A8B6YNX7
uniprot id: A0A8B6YSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

419612:PKD2L2
gene id: 419612:PKD2L2
uniprot id: A0A8B8SRD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane

419612:CMTM3
gene id: 419612:CMTM3
uniprot id: A0A8B8TJM7
names: Subcellular Location Annotation
messages: Membrane

419612:KCNG3
gene id: 419612:KCNG3
uniprot id: A0A8B6YEC7
uniprot id: A0A8B8UFB7
names: Subcellular Location Annotation
messages: Membrane

419612:SCARB2
gene id: 419612:SCARB2
uniprot id: A0A8B6YPU1
names: Similarity
messages: Belongs to the CD36 family.

419612:PC
gene id: 419612:PC
uniprot id: A0A8B6YAK4
uniprot id: A0A8B8TU68
uniprot id: A0A8B8TVF1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

419612:ATXN1
gene id: 419612:ATXN1
uniprot id: A0A8B8RM70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

419612:LOC102516152
gene id: 419612:LOC102516152
uniprot id: T0MID9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:CA1
gene id: 419612:CA1
uniprot id: A0A8B8S8U4
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

419612:LOC102503449
gene id: 419612:LOC102503449
uniprot id: A0A8B8T9P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FAM126A
gene id: 419612:FAM126A
uniprot id: A0A8B6YED9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

419612:LOC116666653
gene id: 419612:LOC116666653
uniprot id: A0A8B8TVP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LHX8
gene id: 419612:LHX8
uniprot id: A0A8B8U7B9
uniprot id: A0A8B8U7C3
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102517818
gene id: 419612:LOC102517818
uniprot id: A0A8B7KGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

419612:ACAD10
gene id: 419612:ACAD10
uniprot id: A0A8B6Y9I6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

419612:TEKT3
gene id: 419612:TEKT3
uniprot id: A0A8B8UJZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

419612:CTBP1
gene id: 419612:CTBP1
uniprot id: A0A8B8U075
uniprot id: A0A8B8U079
uniprot id: A0A8B8U0I1
uniprot id: A0A8B8U192
uniprot id: A0A8B8U1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

419612:SEPTIN1
gene id: 419612:SEPTIN1
uniprot id: A0A8B8REG0
uniprot id: A0A8B8REG7
uniprot id: A0A8B8REH1
uniprot id: A0A8B8REN3
uniprot id: T0MFD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

419612:PPARGC1B
gene id: 419612:PPARGC1B
uniprot id: A0A8B8STW6
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102521143
gene id: 419612:LOC102521143
uniprot id: A0A8B6YNK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:AVL9
gene id: 419612:AVL9
uniprot id: A0A8B8TBZ5
names: Subcellular Location Annotation
messages: Recycling endosome

419612:SOX12
gene id: 419612:SOX12
uniprot id: A0A8B8RKU0
names: Subcellular Location Annotation
messages: Nucleus

419612:TK2
gene id: 419612:TK2
uniprot id: A0A8B8TJD8
uniprot id: A0A8B8TJE2
uniprot id: A0A8B8TJF2
names: Similarity
messages: Belongs to the DCK/DGK family.

419612:ACTN3
gene id: 419612:ACTN3
uniprot id: A0A8B6YBZ1
names: Similarity
messages: Belongs to the alpha-actinin family.

419612:CSF2RB
gene id: 419612:CSF2RB
uniprot id: A0A8B8U1F6
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102523738
gene id: 419612:LOC102523738
uniprot id: A0A8B7K719
names: Similarity
messages: Belongs to the SLBP family.

419612:LOC102505149
gene id: 419612:LOC102505149
uniprot id: A0A8B6YP13
uniprot id: A0A8B7KDR8
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

419612:LOC102519790
gene id: 419612:LOC102519790
uniprot id: A0A8B8RGA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

419612:PCSK2
gene id: 419612:PCSK2
uniprot id: A0A8B8RI96
names: Similarity
messages: Belongs to the peptidase S8 family.

419612:LOC106731107
gene id: 419612:LOC106731107
uniprot id: A0A8B7KGF8
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

419612:BMPR1A
gene id: 419612:BMPR1A
uniprot id: A0A8B8TZZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

419612:LOC102514252
gene id: 419612:LOC102514252
uniprot id: S9XNM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

419612:TAMM41
gene id: 419612:TAMM41
uniprot id: A0A8B6YCI9
uniprot id: A0A8B8RA78
uniprot id: A0A8B8RA95
uniprot id: A0A8B8RCX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

419612:GAL3ST1
gene id: 419612:GAL3ST1
uniprot id: A0A8B8SD34
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

419612:CASTOR2
gene id: 419612:CASTOR2
uniprot id: A0A8B8RBN7
names: Similarity
messages: Belongs to the GATS family.

419612:LOC102516462
gene id: 419612:LOC102516462
uniprot id: A0A8B6YGA1
names: Subcellular Location Annotation
messages: Membrane

419612:GGT7
gene id: 419612:GGT7
uniprot id: A0A8B8RJC9
uniprot id: A0A8B8RJE0
uniprot id: A0A8B8RJE4
uniprot id: A0A8B8RJP0
uniprot id: A0A8B8RL65
uniprot id: A0A8B8RL70
uniprot id: A0A8B8RLM6
uniprot id: A0A8B8RLN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

419612:ZUP1
gene id: 419612:ZUP1
uniprot id: A0A8B6YMY1
uniprot id: A0A8B7KFD3
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

419612:LOC102519285
gene id: 419612:LOC102519285
uniprot id: A0A8B6YNF3
uniprot id: A0A8B8TSZ7
names: Similarity
messages: Belongs to the MS4A family.

419612:LDAH
gene id: 419612:LDAH
uniprot id: A0A8B6YAQ4
uniprot id: A0A8B8UFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

419612:LOC102511840
gene id: 419612:LOC102511840
uniprot id: A0A8B7KET6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC116657482
gene id: 419612:LOC116657482
uniprot id: A0A8B8RF15
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:WNT9A
gene id: 419612:WNT9A
uniprot id: A0A8B8SSS8
uniprot id: A0A8B8SUD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

419612:CYRIA
gene id: 419612:CYRIA
uniprot id: A0A8B8UEE2
uniprot id: A0A8B8UFU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

419612:LOC102511300
gene id: 419612:LOC102511300
uniprot id: A0A8B8T083
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

419612:BORCS7
gene id: 419612:BORCS7
uniprot id: A0A8B6YDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Lysosome membrane
messages: Membrane

419612:PRUNE1
gene id: 419612:PRUNE1
uniprot id: A0A8B6YH73
uniprot id: A0A8B7KC10
uniprot id: A0A8B8RR58
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

419612:RNF13
gene id: 419612:RNF13
uniprot id: A0A8B6YHS2
names: Subcellular Location Annotation
messages: Membrane

419612:SPG21
gene id: 419612:SPG21
uniprot id: A0A8B8T3J2
names: Function
messages: May play a role as a negative regulatory factor in CD4-dependent T-cell activation.

419612:MYF5
gene id: 419612:MYF5
uniprot id: A0A8B6YJF5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

419612:RPL23A
gene id: 419612:RPL23A
uniprot id: A0A8B6YJM3
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

419612:CHPT1
gene id: 419612:CHPT1
uniprot id: A0A8B8U471
uniprot id: A0A8B8U4Z5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

419612:DGKH
gene id: 419612:DGKH
uniprot id: A0A8B7K459
uniprot id: A0A8B8UBI5
uniprot id: A0A8B8UBI7
uniprot id: A0A8B8UBJ4
uniprot id: A0A8B8UC95
uniprot id: A0A8B8UCA0
uniprot id: A0A8B8UCA5
uniprot id: A0A8B8UCE6
uniprot id: A0A8B8UCW3
uniprot id: A0A8B8UCX0
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

419612:SPATA5L1
gene id: 419612:SPATA5L1
uniprot id: A0A8B8T586
names: Similarity
messages: Belongs to the AAA ATPase family.

419612:MACO1
gene id: 419612:MACO1
uniprot id: A0A8B8UAW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Plays a role in the regulation of neuronal activity.
messages: Rough endoplasmic reticulum membrane

419612:LOC102506044
gene id: 419612:LOC102506044
uniprot id: A0A8B6YGT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

419612:ACLY
gene id: 419612:ACLY
uniprot id: A0A8B6YFF1
uniprot id: A0A8B7K902
uniprot id: A0A8B7KB37
uniprot id: A0A8B8R516
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

419612:EVA1B
gene id: 419612:EVA1B
uniprot id: A0A8B8UB88
names: Similarity
messages: Belongs to the EVA1 family.

419612:SUZ12
gene id: 419612:SUZ12
uniprot id: A0A8B6YJK6
uniprot id: A0A8B8R6L9
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

419612:PRPF38B
gene id: 419612:PRPF38B
uniprot id: A0A8B6YBK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

419612:PACSIN2
gene id: 419612:PACSIN2
uniprot id: A0A8B8U109
uniprot id: A0A8B8U217
uniprot id: A0A8B8U2A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cell projection
messages: Cytoplasm
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

419612:LOC102508975
gene id: 419612:LOC102508975
uniprot id: S9XI63
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

419612:STAG1
gene id: 419612:STAG1
uniprot id: A0A8B8TNP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

419612:ACD
gene id: 419612:ACD
uniprot id: A0A8B6YC47
uniprot id: A0A8B7K7L1
uniprot id: A0A8B7K9F5
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

419612:CAP1
gene id: 419612:CAP1
uniprot id: A0A8B7KE62
uniprot id: A0A8B8U6A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Membrane

419612:SGO2
gene id: 419612:SGO2
uniprot id: A0A8B8T149
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

419612:SF3B4
gene id: 419612:SF3B4
uniprot id: A0A8B6YL45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

419612:NUDT7
gene id: 419612:NUDT7
uniprot id: A0A8B6YA05
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

419612:OSBPL6
gene id: 419612:OSBPL6
uniprot id: A0A8B8T061
uniprot id: A0A8B8T062
uniprot id: A0A8B8T0L1
uniprot id: A0A8B8T0N1
uniprot id: A0A8B8T0N6
uniprot id: A0A8B8T135
names: Similarity
messages: Belongs to the OSBP family.

419612:SLC29A1
gene id: 419612:SLC29A1
uniprot id: A0A8B8RMA4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

419612:SNX13
gene id: 419612:SNX13
uniprot id: A0A8B6YLM0
uniprot id: A0A8B7KDH6
uniprot id: A0A8B8TCB3
uniprot id: A0A8B8TD92
names: Similarity
messages: Belongs to the sorting nexin family.

419612:CHRM2
gene id: 419612:CHRM2
uniprot id: A0A8B8TB28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

419612:SGO1
gene id: 419612:SGO1
uniprot id: A0A8B8TQP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

419612:FGFBP3
gene id: 419612:FGFBP3
uniprot id: A0A8B8TZ37
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

419612:TMEM245
gene id: 419612:TMEM245
uniprot id: A0A8B7K7N8
uniprot id: A0A8B8SVL6
uniprot id: A0A8B8SW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

419612:NGFR
gene id: 419612:NGFR
uniprot id: A0A8B8R6P2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SUPT5H
gene id: 419612:SUPT5H
uniprot id: A0A8B7K5E0
uniprot id: A0A8B7K5G6
uniprot id: A0A8B8TI87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus

419612:BEX4
gene id: 419612:BEX4
uniprot id: A0A8B8SP70
names: Similarity
messages: Belongs to the BEX family.

419612:GABARAPL2
gene id: 419612:GABARAPL2
uniprot id: A0A8B8TK91
uniprot id: A0A8B8TKA9
names: Similarity
messages: Belongs to the ATG8 family.

419612:NR2E1
gene id: 419612:NR2E1
uniprot id: A0A8B8TFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

419612:CRKL
gene id: 419612:CRKL
uniprot id: A0A8B6YCD2
names: Similarity
messages: Belongs to the CRK family.

419612:CPLX3
gene id: 419612:CPLX3
uniprot id: A0A8B6YCX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

419612:MMP8
gene id: 419612:MMP8
uniprot id: A0A8B7KAW2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

419612:TGM7
gene id: 419612:TGM7
uniprot id: A0A8B7K632
uniprot id: A0A8B8T5G8
uniprot id: A0A8B8T5L5
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

419612:MTMR1
gene id: 419612:MTMR1
uniprot id: A0A8B8SMZ1
uniprot id: A0A8B8SN02
uniprot id: A0A8B8SNY8
uniprot id: A0A8B8SPA1
uniprot id: A0A8B8SPA6
uniprot id: A0A8B8SQ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

419612:PKP3
gene id: 419612:PKP3
uniprot id: A0A8B8TVF4
uniprot id: A0A8B8TWI5
names: Similarity
messages: Belongs to the beta-catenin family.

419612:CPNE2
gene id: 419612:CPNE2
uniprot id: A0A8B6YAW3
uniprot id: A0A8B8TJ66
names: Similarity
messages: Belongs to the copine family.

419612:CLPTM1
gene id: 419612:CLPTM1
uniprot id: A0A8B8THQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

419612:LOC102505292
gene id: 419612:LOC102505292
uniprot id: A0A8B6YGJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:JRK
gene id: 419612:JRK
uniprot id: A0A8B8S1V9
names: Subcellular Location Annotation
messages: Nucleus

419612:SPIN2B
gene id: 419612:SPIN2B
uniprot id: S9XBD1
names: Similarity
messages: Belongs to the SPIN/STSY family.

419612:LOC102505437
gene id: 419612:LOC102505437
uniprot id: A0A8B6YCX9
names: Similarity
messages: Belongs to the MHC class II family.

419612:PLD3
gene id: 419612:PLD3
uniprot id: A0A8B6YAK2
names: Similarity
messages: Belongs to the phospholipase D family.

419612:TRAM1L1
gene id: 419612:TRAM1L1
uniprot id: A0A8B8TZL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

419612:PHACTR2
gene id: 419612:PHACTR2
uniprot id: A0A8B8TFD6
uniprot id: A0A8B8TFE0
uniprot id: A0A8B8TFE1
uniprot id: A0A8B8TFE2
uniprot id: A0A8B8TFE6
uniprot id: A0A8B8TFE7
uniprot id: A0A8B8TFH2
uniprot id: A0A8B8TFH7
uniprot id: A0A8B8TGR8
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

419612:TMEM17
gene id: 419612:TMEM17
uniprot id: A0A8B8UG38
names: Subcellular Location Annotation
messages: Membrane

419612:ZNF500
gene id: 419612:ZNF500
uniprot id: A0A8B8RG61
names: Subcellular Location Annotation
messages: Nucleus

419612:ACAP1
gene id: 419612:ACAP1
uniprot id: A0A8B8UJ03
uniprot id: A0A8B8UJF2
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

419612:ACADVL
gene id: 419612:ACADVL
uniprot id: A0A8B7K3Y7
uniprot id: A0A8B7K456
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

419612:NID2
gene id: 419612:NID2
uniprot id: A0A8B8T6P9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

419612:ADCY9
gene id: 419612:ADCY9
uniprot id: A0A8B8RI62
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

419612:GPC2
gene id: 419612:GPC2
uniprot id: A0A8B8REE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

419612:LIFR
gene id: 419612:LIFR
uniprot id: A0A8B8SA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

419612:ENDOU
gene id: 419612:ENDOU
uniprot id: A0A8B7KEV8
uniprot id: A0A8B8U2F4
uniprot id: A0A8B8U2Y5
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

419612:LOC102506783
gene id: 419612:LOC102506783
uniprot id: A0A8B6YMR0
names: Similarity
messages: Belongs to the intermediate filament family.

419612:GJB6
gene id: 419612:GJB6
uniprot id: A0A8B8UCT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

419612:PODXL2
gene id: 419612:PODXL2
uniprot id: A0A8B8R9L5
uniprot id: A0A8B8R9R0
uniprot id: A0A8B8RCE4
names: Subcellular Location Annotation
messages: Membrane

419612:SH2D1A
gene id: 419612:SH2D1A
uniprot id: A0A8B8SN64
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.

419612:STC2
gene id: 419612:STC2
uniprot id: S9YDE7
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

419612:SMC1A
gene id: 419612:SMC1A
uniprot id: A0A8B8SPI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

419612:LOC102517213
gene id: 419612:LOC102517213
uniprot id: S9WY93
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LETMD1
gene id: 419612:LETMD1
uniprot id: A0A8B6YMG7
uniprot id: A0A8B8U2D6
uniprot id: A0A8B8U2D7
uniprot id: A0A8B8U2W0
uniprot id: A0A8B8U3L3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

419612:LOC102505616
gene id: 419612:LOC102505616
uniprot id: A0A8B7KGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:EIF2B1
gene id: 419612:EIF2B1
uniprot id: A0A8B7K620
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

419612:SEPHS2
gene id: 419612:SEPHS2
uniprot id: A0A8B6YRL2
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

419612:CREB1
gene id: 419612:CREB1
uniprot id: A0A8B8T0S6
uniprot id: A0A8B8T0T2
uniprot id: A0A8B8T1Q2
uniprot id: S9YG08
names: Subcellular Location Annotation
messages: Nucleus

419612:GPATCH1
gene id: 419612:GPATCH1
uniprot id: A0A8B6Y786
names: Similarity
messages: Belongs to the GPATCH1 family.

419612:PLA2G2C
gene id: 419612:PLA2G2C
uniprot id: A0A8B7KCB6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

419612:RNASE4
gene id: 419612:RNASE4
uniprot id: A0A8B8T6C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

419612:ACP5
gene id: 419612:ACP5
uniprot id: A0A8B8RUI7
names: Cofactor
messages: Binds 2 iron ions per subunit.

419612:MYO1C
gene id: 419612:MYO1C
uniprot id: A0A8B6YFP0
uniprot id: A0A8B8R5X0
uniprot id: A0A8B8R632
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

419612:ZMYND10
gene id: 419612:ZMYND10
uniprot id: A0A8B7KEE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ZMYND10 family.
messages: Dynein axonemal particle
messages: Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins.
messages: centriolar satellite

419612:HOXB3
gene id: 419612:HOXB3
uniprot id: A0A8B8R9L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

419612:GPR35
gene id: 419612:GPR35
uniprot id: A0A8B8T2U7
uniprot id: A0A8B8T3N4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:ATP5MC3
gene id: 419612:ATP5MC3
uniprot id: A0A8B8T0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

419612:PRKAA2
gene id: 419612:PRKAA2
uniprot id: A0A8B8U6Q7
uniprot id: A0A8B8U7L9
uniprot id: A0A8B8U7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: Cytoplasm
messages: Nucleus

419612:CLDN20
gene id: 419612:CLDN20
uniprot id: S9Y2M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

419612:KCNAB3
gene id: 419612:KCNAB3
uniprot id: A0A8B6YQ36
uniprot id: A0A8B8UJ88
uniprot id: A0A8B8UKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cytoplasm

419612:LASP1
gene id: 419612:LASP1
uniprot id: A0A8B8R786
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

419612:GABPA
gene id: 419612:GABPA
uniprot id: A0A8B8SSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:PRDM6
gene id: 419612:PRDM6
uniprot id: A0A8B8SQQ8
uniprot id: A0A8B8SSP3
names: Subcellular Location Annotation
messages: Nucleus

419612:USP36
gene id: 419612:USP36
uniprot id: A0A8B8R3S0
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

419612:NDUFS7
gene id: 419612:NDUFS7
uniprot id: A0A8B8RVM1
uniprot id: A0A8B8RVN4
uniprot id: A0A8B8RWU2
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

419612:LOC102523749
gene id: 419612:LOC102523749
uniprot id: S9YDH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LMOD2
gene id: 419612:LMOD2
uniprot id: A0A8B8TBA1
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

419612:WDR24
gene id: 419612:WDR24
uniprot id: A0A8B6Y589
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR24 family.
messages: Lysosome membrane

419612:LOC102513538
gene id: 419612:LOC102513538
uniprot id: A0A8B8THE7
uniprot id: A0A8B8TIL0
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

419612:SH3GL2
gene id: 419612:SH3GL2
uniprot id: A0A8B8STZ1
uniprot id: A0A8B8SUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

419612:EMP1
gene id: 419612:EMP1
uniprot id: T0MIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

419612:GOT2
gene id: 419612:GOT2
uniprot id: A0A8B6YMW6
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

419612:RECQL5
gene id: 419612:RECQL5
uniprot id: A0A8B7K4A7
uniprot id: A0A8B7K4U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

419612:IL36G
gene id: 419612:IL36G
uniprot id: A0A8B7K9H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

419612:FBN2
gene id: 419612:FBN2
uniprot id: A0A8B8SQU9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:PGLS
gene id: 419612:PGLS
uniprot id: A0A8B8RUY4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

419612:FAM122C
gene id: 419612:FAM122C
uniprot id: A0A8B7KGC4
uniprot id: A0A8B8SJW9
uniprot id: A0A8B8SJX3
uniprot id: A0A8B8SMA2
names: Similarity
messages: Belongs to the FAM122 family.

419612:MICOS13
gene id: 419612:MICOS13
uniprot id: A0A8B6YA94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

419612:LOC102522096
gene id: 419612:LOC102522096
uniprot id: A0A8B6YLW8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

419612:SGK2
gene id: 419612:SGK2
uniprot id: A0A8B7KGV1
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:SPTLC2
gene id: 419612:SPTLC2
uniprot id: A0A8B8T7W0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

419612:CERS2
gene id: 419612:CERS2
uniprot id: A0A8B8RSK5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

419612:MBD4
gene id: 419612:MBD4
uniprot id: A0A8B7K6U9
uniprot id: A0A8B7K6X8
uniprot id: A0A8B7K7C7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with MLH1.
messages: Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
messages: Nucleus

419612:PNCK
gene id: 419612:PNCK
uniprot id: A0A8B8SL47
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:MYH14
gene id: 419612:MYH14
uniprot id: A0A8B7KB32
uniprot id: A0A8B8TMP3
uniprot id: A0A8B8TMQ2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

419612:LOC102503586
gene id: 419612:LOC102503586
uniprot id: A0A8B6YI38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MOSPD1
gene id: 419612:MOSPD1
uniprot id: A0A8B8SJX4
names: Subcellular Location Annotation
messages: Membrane

419612:RPS18
gene id: 419612:RPS18
uniprot id: A0A8B6YCW8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Component of the small ribosomal subunit.

419612:RBP5
gene id: 419612:RBP5
uniprot id: A0A8B6Y6R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

419612:GPATCH11
gene id: 419612:GPATCH11
uniprot id: A0A8B8UFW4
names: Similarity
messages: Belongs to the GPATCH11 family.

419612:SH3RF3
gene id: 419612:SH3RF3
uniprot id: A0A8B8U4Q7
uniprot id: A0A8B8U5N9
names: Similarity
messages: Belongs to the SH3RF family.

419612:GDNF
gene id: 419612:GDNF
uniprot id: A0A8B7KA63
uniprot id: A0A8B8SA37
uniprot id: S9YA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

419612:CACNA1C
gene id: 419612:CACNA1C
uniprot id: A0A8B8SHB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1C subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic density membrane
messages: T-tubule
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.
messages: dendrite
messages: sarcolemma

419612:SOX14
gene id: 419612:SOX14
uniprot id: S9X731
names: Subcellular Location Annotation
messages: Nucleus

419612:KAT6A
gene id: 419612:KAT6A
uniprot id: A0A8B8S469
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

419612:NOXA1
gene id: 419612:NOXA1
uniprot id: A0A8B8SXZ2
uniprot id: A0A8B8SXZ8
uniprot id: A0A8B8SY29
uniprot id: A0A8B8SYE7
uniprot id: A0A8B8SYI6
uniprot id: A0A8B8SZ58
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

419612:LOC102508136
gene id: 419612:LOC102508136
uniprot id: A0A8B6YKU0
uniprot id: A0A8B8RT46
uniprot id: A0A8B8RU28
uniprot id: A0A8B8RV20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KXD1 family.
messages: Component of the 60S subunit of the ribosome. Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Lysosome membrane
messages: Nucleus
messages: Part of the 60S ribosomal subunit. Interacts with UBQLN1 (via UBA domain).

419612:LOC106729435
gene id: 419612:LOC106729435
uniprot id: A0A8B8UGN9
uniprot id: A0A8B8UHA3
names: Similarity
messages: Belongs to the actin family.

419612:ACTRT3
gene id: 419612:ACTRT3
uniprot id: S9WQK1
names: Similarity
messages: Belongs to the actin family.

419612:SDC2
gene id: 419612:SDC2
uniprot id: A0A8B6YQK1
uniprot id: A0A8B7KGT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

419612:DBNDD1
gene id: 419612:DBNDD1
uniprot id: A0A8B8RRM8
uniprot id: A0A8B8RRN3
uniprot id: A0A8B8RSD0
uniprot id: A0A8B8RTM8
names: Similarity
messages: Belongs to the dysbindin family.

419612:CSTB
gene id: 419612:CSTB
uniprot id: A0A8B8UDE7
names: Similarity
messages: Belongs to the cystatin family.

419612:LMOD3
gene id: 419612:LMOD3
uniprot id: A0A8B8R7N6
names: Subcellular Location Annotation
messages: cytoskeleton

419612:LOC116659750
gene id: 419612:LOC116659750
uniprot id: A0A8B8S063
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:SNAP23
gene id: 419612:SNAP23
uniprot id: A0A8B6YAJ3
uniprot id: A0A8B8T4V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

419612:PNPLA6
gene id: 419612:PNPLA6
uniprot id: A0A8B8RVZ0
uniprot id: A0A8B8RVZ3
uniprot id: A0A8B8RX64
uniprot id: A0A8B8RX69
uniprot id: A0A8B8RXF7
uniprot id: A0A8B8RXG2
uniprot id: A0A8B8RXR3
uniprot id: A0A8B8RXR8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:EXTL1
gene id: 419612:EXTL1
uniprot id: A0A8B7KDB2
uniprot id: A0A8B7KF57
uniprot id: S9WG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:DDB1
gene id: 419612:DDB1
uniprot id: A0A8B6Y618
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDB1 family.
messages: Component of complexes involved in DNA repair and protein ubiquitination. May play a role in the regulation of the circadian clock.
messages: Component of the UV-DDB complex.
messages: Nucleus
messages: The core of the protein consists of three WD40 beta-propeller domains.

419612:FUCA1
gene id: 419612:FUCA1
uniprot id: A0A8B8UAK8
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

419612:PRRT2
gene id: 419612:PRRT2
uniprot id: A0A8B8REI3
uniprot id: A0A8B8RGH3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

419612:GHRHR
gene id: 419612:GHRHR
uniprot id: A0A8B8TDG1
names: Subcellular Location Annotation
messages: Membrane

419612:MAPK6
gene id: 419612:MAPK6
uniprot id: A0A8B8T486
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

419612:LOC116667773
gene id: 419612:LOC116667773
uniprot id: A0A8B8U5U4
names: Subcellular Location Annotation
messages: Nucleus

419612:CA3
gene id: 419612:CA3
uniprot id: A0A8B6YS34
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

419612:LOC102515341
gene id: 419612:LOC102515341
uniprot id: A0A8B8SR98
uniprot id: A0A8B8SRA1
uniprot id: A0A8B8SRA6
uniprot id: A0A8B8SRZ8
uniprot id: A0A8B8SS02
uniprot id: A0A8B8SSC6
uniprot id: A0A8B8SSD1
uniprot id: A0A8B8ST48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

419612:GUCY1B1
gene id: 419612:GUCY1B1
uniprot id: A0A8B8RVY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

419612:CASQ1
gene id: 419612:CASQ1
uniprot id: A0A8B6Y9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

419612:PCMT1
gene id: 419612:PCMT1
uniprot id: A0A8B6YG13
uniprot id: A0A8B6YG24
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

419612:GFRA4
gene id: 419612:GFRA4
uniprot id: A0A8B8RKJ7
uniprot id: A0A8B8RKZ7
names: Similarity
messages: Belongs to the GDNFR family.

419612:NKD2
gene id: 419612:NKD2
uniprot id: A0A8B8S4Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

419612:LOC116661476
gene id: 419612:LOC116661476
uniprot id: A0A8B8SI89
names: Similarity
messages: Belongs to the nanos family.

419612:GNG2
gene id: 419612:GNG2
uniprot id: S9WKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

419612:PDSS1
gene id: 419612:PDSS1
uniprot id: A0A8B8SHA9
uniprot id: A0A8B8SJT5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

419612:PRDM10
gene id: 419612:PRDM10
uniprot id: A0A8B8SD42
uniprot id: A0A8B8SD49
uniprot id: A0A8B8SEA3
uniprot id: A0A8B8SEF3
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

419612:TRAPPC4
gene id: 419612:TRAPPC4
uniprot id: S9YVG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

419612:TMEM53
gene id: 419612:TMEM53
uniprot id: T0NIP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

419612:GMFB
gene id: 419612:GMFB
uniprot id: A0A8B6YG05
uniprot id: A0A8B8T729
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

419612:SMG7
gene id: 419612:SMG7
uniprot id: A0A8B8RND2
uniprot id: A0A8B8RNR9
uniprot id: A0A8B8RQ32
uniprot id: A0A8B8RQH1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

419612:LOC102504745
gene id: 419612:LOC102504745
uniprot id: A0A8B8TBN4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

419612:LOC102518170
gene id: 419612:LOC102518170
uniprot id: A0A8B6YBJ1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102507195
gene id: 419612:LOC102507195
uniprot id: A0A8B6YNT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

419612:OTOP3
gene id: 419612:OTOP3
uniprot id: A0A8B8R429
uniprot id: A0A8B8R6B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

419612:POU3F3
gene id: 419612:POU3F3
uniprot id: A0A8B8SK03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

419612:NLRP5
gene id: 419612:NLRP5
uniprot id: A0A8B8TMA4
names: Similarity
messages: Belongs to the NLRP family.

419612:LOC102521236
gene id: 419612:LOC102521236
uniprot id: A0A8B6YCD1
uniprot id: A0A8B8R6K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

419612:SUGP1
gene id: 419612:SUGP1
uniprot id: A0A8B8RSY7
names: Subcellular Location Annotation
messages: Nucleus

419612:CDK3
gene id: 419612:CDK3
uniprot id: A0A8B6Y7X1
uniprot id: A0A8B8R417
uniprot id: A0A8B8R652
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:OLFM3
gene id: 419612:OLFM3
uniprot id: A0A8B6YKZ0
uniprot id: A0A8B6YL64
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

419612:MORF4L2
gene id: 419612:MORF4L2
uniprot id: A0A8B7KH67
names: Subcellular Location Annotation
messages: Nucleus

419612:NPEPPS
gene id: 419612:NPEPPS
uniprot id: A0A8B8R6Y3
uniprot id: A0A8B8R9Q8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

419612:PDYN
gene id: 419612:PDYN
uniprot id: S9WUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opioid activity and may have anti-apoptotic effect.
messages: Secreted

419612:LOC102507497
gene id: 419612:LOC102507497
uniprot id: A0A8B6YAE3
uniprot id: A0A8B7K564
uniprot id: A0A8B7K5A3
names: Subcellular Location Annotation
messages: Membrane

419612:TMEM242
gene id: 419612:TMEM242
uniprot id: A0A8B6YAC3
uniprot id: A0A8B7K6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

419612:LOC116667657
gene id: 419612:LOC116667657
uniprot id: A0A8B8U3P8
names: Similarity
messages: Belongs to the TIM16/PAM16 family.

419612:IRX4
gene id: 419612:IRX4
uniprot id: A0A8B8S5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

419612:NR0B2
gene id: 419612:NR0B2
uniprot id: A0A8B6Y796
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

419612:SNX14
gene id: 419612:SNX14
uniprot id: A0A8B8TDX9
uniprot id: A0A8B8TDY2
uniprot id: A0A8B8TDY3
uniprot id: A0A8B8TE23
uniprot id: A0A8B8TE29
uniprot id: A0A8B8TF83
uniprot id: A0A8B8TF88
names: Similarity
messages: Belongs to the sorting nexin family.

419612:NAA60
gene id: 419612:NAA60
uniprot id: A0A8B8RGD8
uniprot id: A0A8B8RGL0
uniprot id: A0A8B8RIB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

419612:FOXP2
gene id: 419612:FOXP2
uniprot id: A0A8B8TCI7
names: Subcellular Location Annotation
messages: Nucleus

419612:CCR9
gene id: 419612:CCR9
uniprot id: A0A8B6Y683
uniprot id: A0A8B8RAC4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:LOC102507243
gene id: 419612:LOC102507243
uniprot id: A0A8B7K7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

419612:SPEG
gene id: 419612:SPEG
uniprot id: A0A8B8T1Q0
uniprot id: A0A8B8T1Q1
uniprot id: A0A8B8T1Q6
uniprot id: A0A8B8T228
uniprot id: A0A8B8T235
uniprot id: A0A8B8T239
uniprot id: A0A8B8T2A7
uniprot id: A0A8B8T2B3
uniprot id: A0A8B8T2K2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

419612:HAPLN4
gene id: 419612:HAPLN4
uniprot id: A0A8B7KBR0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:OC90
gene id: 419612:OC90
uniprot id: A0A8B8S1I0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

419612:CASQ2
gene id: 419612:CASQ2
uniprot id: A0A8B6YPK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

419612:RNF4
gene id: 419612:RNF4
uniprot id: A0A8B6Y9G5
uniprot id: A0A8B7KBH1
names: Subcellular Location Annotation
messages: Nucleus

419612:TTYH3
gene id: 419612:TTYH3
uniprot id: A0A8B8RCU7
uniprot id: A0A8B8RCY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

419612:LOC116669330
gene id: 419612:LOC116669330
uniprot id: A0A8B8UJK5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

419612:HPDL
gene id: 419612:HPDL
uniprot id: A0A8B6YPZ9
names: Similarity
messages: Belongs to the 4HPPD family.

419612:BID
gene id: 419612:BID
uniprot id: A0A8B8SFD3
uniprot id: A0A8B8SFE2
uniprot id: A0A8B8SGL7
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.
messages: Induces caspases and apoptosis. Counters the protective effect of BCL2.
messages: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
messages: Membrane
messages: Mitochondrion outer membrane

419612:MRPS18C
gene id: 419612:MRPS18C
uniprot id: A0A8B6YKR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

419612:PRKRIP1
gene id: 419612:PRKRIP1
uniprot id: A0A8B6YCD8
names: Similarity
messages: Belongs to the PRKRIP1 family.

419612:ATAD2
gene id: 419612:ATAD2
uniprot id: A0A8B8S1U8
names: Similarity
messages: Belongs to the AAA ATPase family.

419612:CACNA1I
gene id: 419612:CACNA1I
uniprot id: A0A8B8U157
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

419612:DOCK6
gene id: 419612:DOCK6
uniprot id: A0A8B8RUE5
uniprot id: A0A8B8RUE6
uniprot id: A0A8B8RVI6
uniprot id: A0A8B8RVJ1
uniprot id: A0A8B8RVZ2
uniprot id: A0A8B8RVZ8
uniprot id: A0A8B8RWA1
names: Similarity
messages: Belongs to the DOCK family.

419612:NUBP2
gene id: 419612:NUBP2
uniprot id: S9YYB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Nucleus
messages: centrosome

419612:CEBPD
gene id: 419612:CEBPD
uniprot id: A0A8B8S8Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

419612:PADI6
gene id: 419612:PADI6
uniprot id: A0A8B8U8U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

419612:TRIO
gene id: 419612:TRIO
uniprot id: A0A8B8S706
uniprot id: A0A8B8S733
uniprot id: A0A8B8S8C8
uniprot id: A0A8B8S8F8
uniprot id: A0A8B8S8I0
uniprot id: A0A8B8S9B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

419612:LOC102510534
gene id: 419612:LOC102510534
uniprot id: A0A8B7KAR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PVALEF
gene id: 419612:PVALEF
uniprot id: A0A8B8UHW0
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

419612:MAPK9
gene id: 419612:MAPK9
uniprot id: A0A8B8RS40
uniprot id: A0A8B8RS42
uniprot id: A0A8B8RSW8
uniprot id: A0A8B8RSX5
uniprot id: A0A8B8RTQ8
uniprot id: A0A8B8RU22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

419612:POLR3G
gene id: 419612:POLR3G
uniprot id: A0A8B7KC29
uniprot id: A0A8B8SNP7
uniprot id: A0A8B8SPS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

419612:C25H8orf33
gene id: 419612:C25H8orf33
uniprot id: A0A8B8S1Z2
names: Similarity
messages: Belongs to the UPF0488 family.

419612:GPR31
gene id: 419612:GPR31
uniprot id: A0A8B7K7H0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:SCMH1
gene id: 419612:SCMH1
uniprot id: A0A8B7KFK4
uniprot id: A0A8B8U5H4
uniprot id: A0A8B8U5H9
uniprot id: A0A8B8U5I1
uniprot id: A0A8B8U5I6
uniprot id: A0A8B8U6E8
uniprot id: A0A8B8U6G0
uniprot id: A0A8B8U6M5
uniprot id: A0A8B8U6M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

419612:LOC102523398
gene id: 419612:LOC102523398
uniprot id: A0A8B8TVK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102506538
gene id: 419612:LOC102506538
uniprot id: A0A8B6YPC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ST8SIA4
gene id: 419612:ST8SIA4
uniprot id: A0A8B6YG66
uniprot id: A0A8B8SQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

419612:RMND1
gene id: 419612:RMND1
uniprot id: A0A8B6YK18
names: Similarity
messages: Belongs to the RMD1/sif2 family.

419612:HRH1
gene id: 419612:HRH1
uniprot id: S9W3X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:MYO9A
gene id: 419612:MYO9A
uniprot id: A0A8B8S5U8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

419612:LOC102521378
gene id: 419612:LOC102521378
uniprot id: A0A8B6YNK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102518496
gene id: 419612:LOC102518496
uniprot id: A0A8B6YAH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102517823
gene id: 419612:LOC102517823
uniprot id: A0A8B8S6V5
uniprot id: A0A8B8S6W0
uniprot id: A0A8B8S926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

419612:CXCR1
gene id: 419612:CXCR1
uniprot id: A0A8B8T2D2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:PTPN11
gene id: 419612:PTPN11
uniprot id: A0A8B8SC90
uniprot id: A0A8B8SDE9
uniprot id: A0A8B8SDJ8
uniprot id: A0A8B8SES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

419612:PSMB6
gene id: 419612:PSMB6
uniprot id: A0A8B6YFI7
uniprot id: A0A8B7K984
uniprot id: A0A8B8UIW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

419612:CLCF1
gene id: 419612:CLCF1
uniprot id: A0A8B8TU90
uniprot id: A0A8B8TU92
uniprot id: A0A8B8TVC3
uniprot id: A0A8B8TVH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

419612:ATAD1
gene id: 419612:ATAD1
uniprot id: A0A8B6YJ65
uniprot id: A0A8B7KCQ7
names: Similarity
messages: Belongs to the AAA ATPase family.

419612:MVB12B
gene id: 419612:MVB12B
uniprot id: A0A8B8SW98
uniprot id: A0A8B8SWH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

419612:TMEM131
gene id: 419612:TMEM131
uniprot id: A0A8B8S5W4
uniprot id: A0A8B8S7Z4
names: Similarity
messages: Belongs to the TMEM131 family.

419612:KCNE3
gene id: 419612:KCNE3
uniprot id: S9YH68
names: Similarity
messages: Belongs to the potassium channel KCNE family.

419612:FDPS
gene id: 419612:FDPS
uniprot id: A0A8B6Y4M2
uniprot id: A0A8B7K3J2
uniprot id: A0A8B8RPY7
uniprot id: A0A8B8RQH5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

419612:BTN1A1
gene id: 419612:BTN1A1
uniprot id: A0A8B8RMT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

419612:PPFIA3
gene id: 419612:PPFIA3
uniprot id: A0A8B8TGY0
uniprot id: A0A8B8TI58
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

419612:SLC26A3
gene id: 419612:SLC26A3
uniprot id: A0A8B6YG85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
messages: Membrane

419612:LOC116665080
gene id: 419612:LOC116665080
uniprot id: A0A8B8TEM8
names: Similarity
messages: Belongs to the PPDPF family.

419612:HM13
gene id: 419612:HM13
uniprot id: A0A8B8RJ29
uniprot id: A0A8B8RKW0
uniprot id: A0A8B8RLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

419612:UCHL3
gene id: 419612:UCHL3
uniprot id: A0A8B8UDU1
uniprot id: A0A8B8UF75
names: Similarity
messages: Belongs to the peptidase C12 family.

419612:LOC102514155
gene id: 419612:LOC102514155
uniprot id: A0A8B7KAM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RNF182
gene id: 419612:RNF182
uniprot id: S9WWR4
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

419612:SLC14A2
gene id: 419612:SLC14A2
uniprot id: A0A8B8S8M5
uniprot id: A0A8B8S8N1
uniprot id: A0A8B8S9X3
uniprot id: A0A8B8S9X8
uniprot id: A0A8B8SA34
uniprot id: A0A8B8SAW9
uniprot id: A0A8B8SAX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

419612:MEP1A
gene id: 419612:MEP1A
uniprot id: A0A8B8RP42
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:ALDH3A2
gene id: 419612:ALDH3A2
uniprot id: A0A8B8UK56
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

419612:TNFSF13
gene id: 419612:TNFSF13
uniprot id: A0A8B6Y790
uniprot id: A0A8B8UJJ6
names: Similarity
messages: Belongs to the tumor necrosis factor family.

419612:HCN2
gene id: 419612:HCN2
uniprot id: A0A8B8RX30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

419612:MOCS3
gene id: 419612:MOCS3
uniprot id: S9YWE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Interacts with NFS1.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

419612:CCNYL1
gene id: 419612:CCNYL1
uniprot id: A0A8B8T1A1
uniprot id: A0A8B8T1P8
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

419612:SEPTIN10
gene id: 419612:SEPTIN10
uniprot id: A0A8B8U4R1
uniprot id: A0A8B8U4R2
uniprot id: A0A8B8U5J3
uniprot id: A0A8B8U5P4
uniprot id: A0A8B8U5W2
uniprot id: A0A8B8U5W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

419612:TSC22D3
gene id: 419612:TSC22D3
uniprot id: A0A8B6YNV6
uniprot id: A0A8B8SNG8
uniprot id: A0A8B8SNH2
uniprot id: A0A8B8SPE6
uniprot id: A0A8B8SPR1
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

419612:SH3BP5L
gene id: 419612:SH3BP5L
uniprot id: A0A8B8STL9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

419612:USP1
gene id: 419612:USP1
uniprot id: A0A8B8U6X7
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

419612:RPS6KA1
gene id: 419612:RPS6KA1
uniprot id: A0A8B6YJU9
uniprot id: A0A8B7KD10
uniprot id: A0A8B8UA61
uniprot id: A0A8B8UA63
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

419612:PPIL1
gene id: 419612:PPIL1
uniprot id: S9W8S4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

419612:ABLIM1
gene id: 419612:ABLIM1
uniprot id: A0A8B7K9F9
uniprot id: A0A8B7KB65
uniprot id: A0A8B8TWQ6
uniprot id: A0A8B8TWQ7
uniprot id: A0A8B8TWR1
uniprot id: A0A8B8TWR4
uniprot id: A0A8B8TWR5
uniprot id: A0A8B8TWR6
uniprot id: A0A8B8TWR7
uniprot id: A0A8B8TWS0
uniprot id: A0A8B8TWS1
uniprot id: A0A8B8TWS2
uniprot id: A0A8B8TWS3
uniprot id: A0A8B8TWS7
uniprot id: A0A8B8TXS6
uniprot id: A0A8B8TXT1
uniprot id: A0A8B8TXT5
uniprot id: A0A8B8TXU0
uniprot id: A0A8B8TY38
uniprot id: A0A8B8TY43
uniprot id: A0A8B8TY47
uniprot id: A0A8B8TY50
names: Subcellular Location Annotation
messages: Cytoplasm

419612:SLC37A3
gene id: 419612:SLC37A3
uniprot id: A0A8B8TAV8
uniprot id: A0A8B8TB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

419612:TMOD1
gene id: 419612:TMOD1
uniprot id: A0A8B6YI57
names: Subcellular Location Annotation
messages: cytoskeleton

419612:HMGN3
gene id: 419612:HMGN3
uniprot id: A0A8B6YCX8
uniprot id: A0A8B6YCY0
uniprot id: A0A8B7K845
uniprot id: A0A8B7KA95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

419612:FAM120A
gene id: 419612:FAM120A
uniprot id: A0A8B8ST69
uniprot id: A0A8B8STA4
uniprot id: A0A8B8STB0
uniprot id: A0A8B8STR4
uniprot id: A0A8B8SUU7
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

419612:RPL17
gene id: 419612:RPL17
uniprot id: A0A8B6YD31
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

419612:DECR2
gene id: 419612:DECR2
uniprot id: A0A8B6Y6E4
uniprot id: A0A8B8RF34
uniprot id: A0A8B8RF39
uniprot id: A0A8B8RF43
uniprot id: A0A8B8RFA4
uniprot id: A0A8B8RFA9
uniprot id: A0A8B8RFB3
uniprot id: A0A8B8RH27
uniprot id: A0A8B8RHK5
names: Similarity
names: Subunit
messages: Belongs to the NDK family.
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
messages: Monomer, dimer and oligomer.

419612:TSPAN31
gene id: 419612:TSPAN31
uniprot id: A0A8B6YEQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:TMEM263
gene id: 419612:TMEM263
uniprot id: A0A8B8U4W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

419612:IMP4
gene id: 419612:IMP4
uniprot id: A0A8B6YLJ6
names: Subcellular Location Annotation
messages: nucleolus

419612:GLI1
gene id: 419612:GLI1
uniprot id: A0A8B8U3B7
uniprot id: S9X3F9
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

419612:LOC102523271
gene id: 419612:LOC102523271
uniprot id: A0A8B6YNE7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ATP1B1
gene id: 419612:ATP1B1
uniprot id: A0A8B6Y5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

419612:UNC13C
gene id: 419612:UNC13C
uniprot id: A0A8B8T454
names: Subcellular Location Annotation
messages: Cytoplasm

419612:LOC102504499
gene id: 419612:LOC102504499
uniprot id: A0A8B8TUE7
names: Subcellular Location Annotation
messages: Membrane

419612:TLCD5
gene id: 419612:TLCD5
uniprot id: A0A8B7K3I0
uniprot id: A0A8B8SF60
names: Subcellular Location Annotation
messages: Membrane

419612:TBXAS1
gene id: 419612:TBXAS1
uniprot id: A0A8B8TDE0
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:LOC102511137
gene id: 419612:LOC102511137
uniprot id: A0A8B7KGH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:ZNF830
gene id: 419612:ZNF830
uniprot id: A0A8B8R6M4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

419612:TXNL4B
gene id: 419612:TXNL4B
uniprot id: A0A8B6YET8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

419612:LOC102510080
gene id: 419612:LOC102510080
uniprot id: A0A8B6YMR2
names: Similarity
messages: Belongs to the CBP3 family.

419612:SEZ6L2
gene id: 419612:SEZ6L2
uniprot id: A0A8B6YDU5
uniprot id: A0A8B8REI2
uniprot id: A0A8B8RGH9
uniprot id: A0A8B8RH06
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102509016
gene id: 419612:LOC102509016
uniprot id: A0A8B6YK66
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

419612:SLC35B4
gene id: 419612:SLC35B4
uniprot id: A0A8B6YNG3
uniprot id: A0A8B8TAJ2
uniprot id: A0A8B8TAN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

419612:MAGI2
gene id: 419612:MAGI2
uniprot id: A0A8B7KB05
uniprot id: A0A8B8TCR2
uniprot id: A0A8B8TCS8
uniprot id: A0A8B8TCY8
uniprot id: A0A8B8TDZ9
names: Subcellular Location Annotation
messages: Membrane

419612:ATP8A1
gene id: 419612:ATP8A1
uniprot id: A0A8B8UEF4
uniprot id: A0A8B8UEF5
uniprot id: A0A8B8UF16
uniprot id: A0A8B8UF21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

419612:TNFSF14
gene id: 419612:TNFSF14
uniprot id: A0A8B6YCS6
uniprot id: A0A8B7K571
names: Similarity
messages: Belongs to the tumor necrosis factor family.

419612:NDUFA5
gene id: 419612:NDUFA5
uniprot id: A0A8B6YKS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

419612:LOC102510161
gene id: 419612:LOC102510161
uniprot id: A0A8B8TR96
uniprot id: A0A8B8TRB3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:LOC102512709
gene id: 419612:LOC102512709
uniprot id: A0A8B8SN14
names: Similarity
messages: Belongs to the WD repeat EBI family.

419612:LNPEP
gene id: 419612:LNPEP
uniprot id: A0A8B8SRA2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

419612:VPS13D
gene id: 419612:VPS13D
uniprot id: A0A8B8U947
names: Similarity
messages: Belongs to the VPS13 family.

419612:LITAFD
gene id: 419612:LITAFD
uniprot id: A0A8B7KDR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

419612:ETV6
gene id: 419612:ETV6
uniprot id: A0A8B8SFS5
uniprot id: A0A8B8SGW5
uniprot id: A0A8B8SIC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:SEMA6B
gene id: 419612:SEMA6B
uniprot id: A0A8B8RUX1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:PSMD7
gene id: 419612:PSMD7
uniprot id: A0A8B8TL52
names: Similarity
messages: Belongs to the peptidase M67A family.

419612:GAREM1
gene id: 419612:GAREM1
uniprot id: A0A8B8S059
names: Similarity
messages: Belongs to the GAREM family.

419612:EIF2AK3
gene id: 419612:EIF2AK3
uniprot id: A0A8B8S630
uniprot id: A0A8B8S7J5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

419612:DYDC1
gene id: 419612:DYDC1
uniprot id: A0A8B7K6W8
uniprot id: A0A8B8TYU5
uniprot id: A0A8B8TZV7
names: Similarity
messages: Belongs to the dpy-30 family.

419612:SGMS1
gene id: 419612:SGMS1
uniprot id: A0A8B8TZ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

419612:ANKRD13B
gene id: 419612:ANKRD13B
uniprot id: A0A8B8R608
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

419612:TIMM22
gene id: 419612:TIMM22
uniprot id: A0A8B6YGV8
uniprot id: A0A8B8R5Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

419612:WDYHV1
gene id: 419612:WDYHV1
uniprot id: A0A8B8S1Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

419612:EHD2
gene id: 419612:EHD2
uniprot id: A0A8B6YBU3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

419612:POFUT2
gene id: 419612:POFUT2
uniprot id: A0A8B8TVM8
uniprot id: A0A8B8TVR8
uniprot id: A0A8B8TX20
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

419612:HNRNPF
gene id: 419612:HNRNPF
uniprot id: S9XTX2
names: Subcellular Location Annotation
messages: nucleoplasm

419612:LOC102519801
gene id: 419612:LOC102519801
uniprot id: S9WVM5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:KRT78
gene id: 419612:KRT78
uniprot id: A0A8B6YDC9
names: Similarity
messages: Belongs to the intermediate filament family.

419612:TRMT2B
gene id: 419612:TRMT2B
uniprot id: A0A8B8SLN5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SCUBE1
gene id: 419612:SCUBE1
uniprot id: A0A8B8U119
uniprot id: A0A8B8U1F3
uniprot id: A0A8B8U225
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

419612:NPPB
gene id: 419612:NPPB
uniprot id: T0MKL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (By similarity). May also function as a paracrine antifibrotic factor in the heart (By similarity). Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3.
messages: Secreted

419612:PEX6
gene id: 419612:PEX6
uniprot id: A0A8B8RNU0
names: Subcellular Location Annotation
messages: cytosol

419612:ZSCAN26
gene id: 419612:ZSCAN26
uniprot id: A0A8B6YLZ3
uniprot id: A0A8B6YNH0
names: Subcellular Location Annotation
messages: Nucleus

419612:ABI3
gene id: 419612:ABI3
uniprot id: A0A8B8R9K2
names: Similarity
messages: Belongs to the ABI family.

419612:MED9
gene id: 419612:MED9
uniprot id: A0A8B7KG32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

419612:KCNT2
gene id: 419612:KCNT2
uniprot id: A0A8B6YQ00
uniprot id: A0A8B6YRW7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:RPAP2
gene id: 419612:RPAP2
uniprot id: A0A8B8TL57
uniprot id: A0A8B8TLI0
uniprot id: A0A8B8TME0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex. Interacts with transcribing RNA polymerase II phosphorylated on 'Ser-7' on CTD.
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

419612:LOC102521976
gene id: 419612:LOC102521976
uniprot id: A0A8B6YDZ9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC116657651
gene id: 419612:LOC116657651
uniprot id: T0M687
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

419612:LOC102514933
gene id: 419612:LOC102514933
uniprot id: A0A8B8U062
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

419612:ZFHX4
gene id: 419612:ZFHX4
uniprot id: A0A8B8S7B9
uniprot id: A0A8B8S8S6
uniprot id: A0A8B8S9I5
names: Subcellular Location Annotation
messages: Nucleus

419612:HTR2B
gene id: 419612:HTR2B
uniprot id: A0A8B8T2I7
uniprot id: A0A8B8T2T3
uniprot id: A0A8B8T302
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

419612:LLPH
gene id: 419612:LLPH
uniprot id: A0A8B6Y6I9
names: Similarity
messages: Belongs to the learning-associated protein family.

419612:TUBE1
gene id: 419612:TUBE1
uniprot id: A0A8B6YLS9
uniprot id: A0A8B8TEK1
uniprot id: A0A8B8TFR8
names: Similarity
messages: Belongs to the tubulin family.

419612:SLC26A9
gene id: 419612:SLC26A9
uniprot id: A0A8B6YDJ3
uniprot id: A0A8B8RZY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Ion transporter that can act both as an ion channel and anion exchanger. Mainly acts as a chloride channel, which mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane. Also acts as a DIDS- and thiosulfate- sensitive anion exchanger the exchange of chloride for bicarbonate ions across the cell membrane.
messages: Membrane

419612:AJAP1
gene id: 419612:AJAP1
uniprot id: A0A8B8U9F8
names: Subcellular Location Annotation
messages: Membrane

419612:PDGFC
gene id: 419612:PDGFC
uniprot id: A0A8B8RVS9
uniprot id: A0A8B8RX96
uniprot id: A0A8B8RXM2
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102507097
gene id: 419612:LOC102507097
uniprot id: A0A8B6YJM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:AGO1
gene id: 419612:AGO1
uniprot id: A0A8B8UB31
uniprot id: A0A8B8UB37
uniprot id: A0A8B8UBU6
uniprot id: A0A8B8UBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

419612:BTG4
gene id: 419612:BTG4
uniprot id: A0A8B8SET1
names: Similarity
messages: Belongs to the BTG family.

419612:RNF152
gene id: 419612:RNF152
uniprot id: S9Y5M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

419612:GGH
gene id: 419612:GGH
uniprot id: A0A8B8S8M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

419612:FOXH1
gene id: 419612:FOXH1
uniprot id: A0A8B8S2K5
names: Subcellular Location Annotation
messages: Nucleus

419612:HOOK1
gene id: 419612:HOOK1
uniprot id: A0A8B8U6S1
uniprot id: A0A8B8U7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

419612:NUP98
gene id: 419612:NUP98
uniprot id: A0A8B8TS68
uniprot id: A0A8B8TS69
uniprot id: A0A8B8TS74
uniprot id: A0A8B8TS82
uniprot id: A0A8B8TT41
uniprot id: A0A8B8TTA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

419612:TPK1
gene id: 419612:TPK1
uniprot id: A0A8B8TB34
uniprot id: A0A8B8TB37
uniprot id: A0A8B8TB78
uniprot id: A0A8B8TBG3
uniprot id: A0A8B8TC91
uniprot id: A0A8B8TC96
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

419612:MTMR7
gene id: 419612:MTMR7
uniprot id: A0A8B6YRC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

419612:TMEM170A
gene id: 419612:TMEM170A
uniprot id: A0A8B8TK82
uniprot id: A0A8B8TK99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

419612:OS9
gene id: 419612:OS9
uniprot id: A0A8B6YDE5
uniprot id: A0A8B6YDS9
uniprot id: A0A8B6YHJ1
uniprot id: A0A8B7K8F9
uniprot id: A0A8B7KAK1
uniprot id: A0A8B8U3F4
uniprot id: A0A8B8U3F6
uniprot id: A0A8B8U4M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum lumen
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

419612:NOTCH1
gene id: 419612:NOTCH1
uniprot id: A0A8B8SXG6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

419612:LOC102513367
gene id: 419612:LOC102513367
uniprot id: A0A8B8TGI1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

419612:APMAP
gene id: 419612:APMAP
uniprot id: A0A8B8RI80
names: Similarity
messages: Belongs to the strictosidine synthase family.

419612:ZNF277
gene id: 419612:ZNF277
uniprot id: A0A8B6YGK5
uniprot id: A0A8B7KAJ7
names: Similarity
messages: Belongs to the ZNF277 family.

419612:SSH1
gene id: 419612:SSH1
uniprot id: A0A8B8SCC6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

419612:PRPS1
gene id: 419612:PRPS1
uniprot id: A0A8B8SKS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

419612:LOC102523375
gene id: 419612:LOC102523375
uniprot id: A0A8B8SD20
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102509051
gene id: 419612:LOC102509051
uniprot id: A0A8B6YMY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CD48
gene id: 419612:CD48
uniprot id: A0A8B6Y9T6
names: Subcellular Location Annotation
messages: Membrane

419612:LOC106730926
gene id: 419612:LOC106730926
uniprot id: S9W978
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:LOC102517613
gene id: 419612:LOC102517613
uniprot id: A0A8B8RN52
uniprot id: A0A8B8RNI1
uniprot id: A0A8B8RQ86
names: Similarity
messages: Belongs to the MHC class I family.

419612:RP2
gene id: 419612:RP2
uniprot id: A0A8B6YLN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

419612:SPA17
gene id: 419612:SPA17
uniprot id: A0A8B6YA59
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.

419612:COQ5
gene id: 419612:COQ5
uniprot id: A0A8B6Y9A1
uniprot id: A0A8B8SC71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

419612:CKB
gene id: 419612:CKB
uniprot id: A0A8B8T8U6
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

419612:ELMO3
gene id: 419612:ELMO3
uniprot id: A0A8B8TJJ7
uniprot id: A0A8B8TJK7
uniprot id: A0A8B8TKT1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

419612:MYT1L
gene id: 419612:MYT1L
uniprot id: A0A8B8UET4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

419612:DDX24
gene id: 419612:DDX24
uniprot id: A0A8B6YG31
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

419612:ABCA10
gene id: 419612:ABCA10
uniprot id: A0A8B8R4E4
uniprot id: A0A8B8R6M6
uniprot id: A0A8B8R741
names: Subcellular Location Annotation
messages: Membrane

419612:FIBIN
gene id: 419612:FIBIN
uniprot id: T0MJ25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

419612:E2F5
gene id: 419612:E2F5
uniprot id: A0A8B8S7E2
uniprot id: A0A8B8S7F1
uniprot id: A0A8B8S7F7
uniprot id: A0A8B8S8P6
uniprot id: A0A8B8S8Q1
uniprot id: A0A8B8S8V9
uniprot id: A0A8B8S9L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

419612:VPS4A
gene id: 419612:VPS4A
uniprot id: A0A8B8TJV6
uniprot id: A0A8B8TL37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

419612:CASP14
gene id: 419612:CASP14
uniprot id: A0A8B6YJH5
names: Similarity
messages: Belongs to the peptidase C14A family.

419612:RAB18
gene id: 419612:RAB18
uniprot id: A0A8B8SI77
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

419612:TMPRSS5
gene id: 419612:TMPRSS5
uniprot id: A0A8B8SEN6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:CBR3
gene id: 419612:CBR3
uniprot id: A0A8B8S701
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

419612:PTK2
gene id: 419612:PTK2
uniprot id: A0A8B8S1S9
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

419612:EXOC6B
gene id: 419612:EXOC6B
uniprot id: A0A8B6Y939
uniprot id: A0A8B7K4C2
uniprot id: A0A8B8UGK9
uniprot id: A0A8B8UH91
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

419612:LOC102504846
gene id: 419612:LOC102504846
uniprot id: A0A8B6YFJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

419612:MTCH2
gene id: 419612:MTCH2
uniprot id: A0A8B8TRC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:PABPC4
gene id: 419612:PABPC4
uniprot id: A0A8B6YIM8
uniprot id: A0A8B6YMB0
uniprot id: A0A8B7KC36
uniprot id: A0A8B7KCD9
uniprot id: A0A8B7KD43
uniprot id: A0A8B8U5D3
uniprot id: A0A8B8U681
uniprot id: A0A8B8U687
uniprot id: A0A8B8U6A3
uniprot id: A0A8B8U6I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

419612:ARL11
gene id: 419612:ARL11
uniprot id: S9YC84
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

419612:MAT2A
gene id: 419612:MAT2A
uniprot id: A0A8B8S6R8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

419612:PLXNB1
gene id: 419612:PLXNB1
uniprot id: A0A8B8R908
uniprot id: A0A8B8R943
uniprot id: A0A8B8RB55
uniprot id: A0A8B8RBT3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC102521740
gene id: 419612:LOC102521740
uniprot id: A0A8B6YE02
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102517748
gene id: 419612:LOC102517748
uniprot id: A0A8B8UFC3
names: Similarity
messages: Belongs to the NUT family.

419612:MARK1
gene id: 419612:MARK1
uniprot id: A0A8B8RX80
uniprot id: A0A8B8RYJ1
uniprot id: A0A8B8RYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

419612:LOC116658379
gene id: 419612:LOC116658379
uniprot id: A0A8B8RNL3
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

419612:CEP55
gene id: 419612:CEP55
uniprot id: A0A8B6YEF2
names: Subcellular Location Annotation
messages: Cytoplasm

419612:VCP
gene id: 419612:VCP
uniprot id: A0A8B8SUU4
names: Similarity
messages: Belongs to the AAA ATPase family.

419612:SNRPF
gene id: 419612:SNRPF
uniprot id: A0A8B7KBQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

419612:MTHFD1L
gene id: 419612:MTHFD1L
uniprot id: A0A8B8TFP4
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

419612:AP2M1
gene id: 419612:AP2M1
uniprot id: A0A8B6YFD0
uniprot id: A0A8B6YI65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

419612:VAMP8
gene id: 419612:VAMP8
uniprot id: S9X0Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

419612:STT3A
gene id: 419612:STT3A
uniprot id: A0A8B6YA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

419612:LOC102523915
gene id: 419612:LOC102523915
uniprot id: A0A8B6YPV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TOMM20L
gene id: 419612:TOMM20L
uniprot id: A0A8B8T6Y0
uniprot id: A0A8B8T7I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

419612:TTI2
gene id: 419612:TTI2
uniprot id: A0A8B8S3A5
names: Similarity
messages: Belongs to the TTI2 family.

419612:GSG1L2
gene id: 419612:GSG1L2
uniprot id: A0A8B7K4S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

419612:NR6A1
gene id: 419612:NR6A1
uniprot id: A0A8B7KBW9
uniprot id: A0A8B8SW39
uniprot id: A0A8B8SXF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

419612:KATNB1
gene id: 419612:KATNB1
uniprot id: A0A8B6YAV5
uniprot id: A0A8B7K6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome. This interaction is weakly competed by KATNBL1 which has a lower affinity for it. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein, microtubules, NDEL1 and PAFAH1B1. Interacts with KATNAL1; this interaction is weakly competed by KATNBL1 which has a lower affinity for it. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

419612:EMSY
gene id: 419612:EMSY
uniprot id: A0A8B6Y662
uniprot id: A0A8B8TSS2
uniprot id: A0A8B8TSS7
uniprot id: A0A8B8TST1
uniprot id: A0A8B8TST2
uniprot id: A0A8B8TST5
uniprot id: A0A8B8TSU3
uniprot id: A0A8B8TSU5
uniprot id: A0A8B8TSU8
uniprot id: A0A8B8TSV3
uniprot id: A0A8B8TTT2
uniprot id: A0A8B8TTT8
uniprot id: A0A8B8TTU8
uniprot id: A0A8B8TTX0
uniprot id: A0A8B8TTY0
names: Subcellular Location Annotation
messages: Nucleus

419612:KLC1
gene id: 419612:KLC1
uniprot id: A0A8B8T8T2
uniprot id: A0A8B8T8T3
uniprot id: A0A8B8T8T8
uniprot id: A0A8B8T8U1
uniprot id: A0A8B8T8U3
uniprot id: A0A8B8T8X6
uniprot id: A0A8B8T8Y0
uniprot id: A0A8B8T8Y9
uniprot id: A0A8B8T9A1
uniprot id: A0A8B8T9A5
uniprot id: A0A8B8T9T0
uniprot id: A0A8B8T9T5
uniprot id: A0A8B8T9U1
uniprot id: A0A8B8T9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

419612:MRPS5
gene id: 419612:MRPS5
uniprot id: A0A8B6Y9F7
uniprot id: A0A8B8S7W5
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

419612:C4H9orf116
gene id: 419612:C4H9orf116
uniprot id: A0A8B8SY83
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: cilium axoneme

419612:TRIM67
gene id: 419612:TRIM67
uniprot id: A0A8B8TZP6
names: Subcellular Location Annotation
messages: cytoskeleton

419612:SLC44A3
gene id: 419612:SLC44A3
uniprot id: A0A8B8TLA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:NLRP12
gene id: 419612:NLRP12
uniprot id: A0A8B7K8I3
names: Similarity
messages: Belongs to the NLRP family.

419612:CSN2
gene id: 419612:CSN2
uniprot id: A0A8B8R955
uniprot id: A0A8B8R977
uniprot id: A0A8B8R9D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-casein family.
messages: Important role in determination of the surface properties of the casein micelles.
messages: Secreted

419612:ATP6V1G1
gene id: 419612:ATP6V1G1
uniprot id: S9WVD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

419612:FANCC
gene id: 419612:FANCC
uniprot id: A0A8B8STF9
uniprot id: A0A8B8SUY2
uniprot id: A0A8B8SUY7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

419612:LOC116667836
gene id: 419612:LOC116667836
uniprot id: A0A8B8U6F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:DBNL
gene id: 419612:DBNL
uniprot id: A0A8B8SBC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Early endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

419612:OPA3
gene id: 419612:OPA3
uniprot id: A0A8B6YBX1
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

419612:TPRKB
gene id: 419612:TPRKB
uniprot id: A0A8B8UGT0
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

419612:NAA35
gene id: 419612:NAA35
uniprot id: A0A8B8SUB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

419612:LHFPL2
gene id: 419612:LHFPL2
uniprot id: A0A8B8SLK3
names: Subcellular Location Annotation
messages: Membrane

419612:TCF7L2
gene id: 419612:TCF7L2
uniprot id: A0A8B8TWV4
uniprot id: A0A8B8TWV7
uniprot id: A0A8B8TWV8
uniprot id: A0A8B8TWW1
uniprot id: A0A8B8TWW2
uniprot id: A0A8B8TWW3
uniprot id: A0A8B8TWW6
uniprot id: A0A8B8TWW7
uniprot id: A0A8B8TWW8
uniprot id: A0A8B8TWX0
uniprot id: A0A8B8TWX1
uniprot id: A0A8B8TWX3
uniprot id: A0A8B8TWX4
uniprot id: A0A8B8TWX6
uniprot id: A0A8B8TWX7
uniprot id: A0A8B8TWX9
uniprot id: A0A8B8TWY1
uniprot id: A0A8B8TWY3
uniprot id: A0A8B8TWY4
uniprot id: A0A8B8TWY5
uniprot id: A0A8B8TWY7
uniprot id: A0A8B8TWY9
uniprot id: A0A8B8TWZ0
uniprot id: A0A8B8TWZ3
uniprot id: A0A8B8TXX4
uniprot id: A0A8B8TXX9
uniprot id: A0A8B8TXY4
uniprot id: A0A8B8TXY9
uniprot id: A0A8B8TXZ9
uniprot id: A0A8B8TY04
uniprot id: A0A8B8TY09
uniprot id: A0A8B8TY83
uniprot id: A0A8B8TY88
uniprot id: A0A8B8TY93
uniprot id: A0A8B8TY97
uniprot id: A0A8B8TYA2
uniprot id: A0A8B8TYA7
uniprot id: A0A8B8TYB1
uniprot id: A0A8B8TYB6
uniprot id: A0A8B8TYC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

419612:TSPAN19
gene id: 419612:TSPAN19
uniprot id: A0A8B8U4S2
uniprot id: A0A8B8U4S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:LOC102507214
gene id: 419612:LOC102507214
uniprot id: A0A8B6Y962
uniprot id: A0A8B7K6J2
uniprot id: A0A8B8UBI0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

419612:EIF3L
gene id: 419612:EIF3L
uniprot id: A0A8B6Y8B6
uniprot id: A0A8B8U0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RRN3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

419612:MACIR
gene id: 419612:MACIR
uniprot id: S9WTN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

419612:HOXA5
gene id: 419612:HOXA5
uniprot id: A0A8B8TBX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

419612:LOC102513337
gene id: 419612:LOC102513337
uniprot id: A0A8B7K7K9
names: Similarity
messages: Belongs to the HPF1 family.

419612:RPAP1
gene id: 419612:RPAP1
uniprot id: A0A8B6Y8R3
uniprot id: A0A8B7K6V7
names: Similarity
messages: Belongs to the RPAP1 family.

419612:LOC102521703
gene id: 419612:LOC102521703
uniprot id: A0A8B8RZE9
names: Subcellular Location Annotation
messages: Membrane

419612:BRCC3
gene id: 419612:BRCC3
uniprot id: A0A8B8SMP9
uniprot id: A0A8B8SNR0
uniprot id: A0A8B8SPV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Component of the ARISC complex, at least composed of UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Component of the BRCA1-A complex, at least composed of BRCA1, BARD1, UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. In the BRCA1-A complex, interacts directly with ABRAXAS1 and BABAM2. Component of the BRISC complex, at least composed of ABRAXAS2, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Identified in a complex with SHMT2 and the other subunits of the BRISC complex. In the BRISC complex, interacts directly with ABRAXAS2. Identified in a complex with ABRAXAS2 and NUMA1. The BRISC complex interacts with the CSN complex. Component of the BRCA1/BRCA2 containing complex (BRCC), which also contains BRCA1, BRCA2, BARD1, BABAM2 and RAD51. BRCC is a ubiquitin E3 ligase complex that enhances cellular survival following DNA damage. Interacts with BRCA1. Binds polyubiquitin. Interacts with PWWP2B. Interacts with HDAC1; this interaction is enhanced in the presence of PWWP2B.
messages: Cytoplasm
messages: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
messages: Nucleus
messages: spindle pole

419612:GJA5
gene id: 419612:GJA5
uniprot id: A0A8B7K6B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

419612:STARD3
gene id: 419612:STARD3
uniprot id: A0A8B6Y848
uniprot id: A0A8B6Y8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

419612:COQ8B
gene id: 419612:COQ8B
uniprot id: A0A8B6YK67
uniprot id: A0A8B7KDJ6
uniprot id: A0A8B7KFE3
uniprot id: A0A8B8TI57
uniprot id: A0A8B8TI67
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

419612:SSTR3
gene id: 419612:SSTR3
uniprot id: A0A8B8U602
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:MAPRE3
gene id: 419612:MAPRE3
uniprot id: A0A8B7KFC6
uniprot id: A0A8B8UFI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

419612:LOC102513725
gene id: 419612:LOC102513725
uniprot id: A0A8B8TJ33
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

419612:LOC102524013
gene id: 419612:LOC102524013
uniprot id: A0A8B6YIB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102510064
gene id: 419612:LOC102510064
uniprot id: A0A8B8T2A0
uniprot id: A0A8B8T2M4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

419612:LOC102522586
gene id: 419612:LOC102522586
uniprot id: A0A8B8TH35
uniprot id: S9XM29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

419612:LOC102511405
gene id: 419612:LOC102511405
uniprot id: A0A8B8R7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

419612:DNTT
gene id: 419612:DNTT
uniprot id: A0A8B6Y7V9
uniprot id: A0A8B6YA93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus
messages: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.

419612:SEMA4B
gene id: 419612:SEMA4B
uniprot id: A0A8B8S506
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102520557
gene id: 419612:LOC102520557
uniprot id: A0A8B6YKT4
names: Subcellular Location Annotation
messages: Membrane

419612:TRIM15
gene id: 419612:TRIM15
uniprot id: A0A8B8RMI2
names: Subcellular Location Annotation
messages: Cytoplasm

419612:DMRT1
gene id: 419612:DMRT1
uniprot id: A0A8B8SUN1
uniprot id: A0A8B8SV25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

419612:ABCC11
gene id: 419612:ABCC11
uniprot id: A0A8B8TIT3
names: Subcellular Location Annotation
messages: Membrane

419612:ITPR3
gene id: 419612:ITPR3
uniprot id: A0A8B8RLC0
uniprot id: A0A8B8RLM2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

419612:LOC102508775
gene id: 419612:LOC102508775
uniprot id: A0A8B8RAQ6
uniprot id: A0A8B8RAQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

419612:PPP1R3B
gene id: 419612:PPP1R3B
uniprot id: A0A8B8S391
uniprot id: A0A8B8S532
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

419612:LOC102524612
gene id: 419612:LOC102524612
uniprot id: A0A8B8S811
names: Similarity
messages: Belongs to the serpin family.

419612:FAM178B
gene id: 419612:FAM178B
uniprot id: A0A8B7K534
uniprot id: A0A8B8S5J8
uniprot id: A0A8B8S5L3
uniprot id: A0A8B8S6X6
uniprot id: A0A8B8S729
uniprot id: A0A8B8S7N2
uniprot id: A0A8B8S7N4
names: Similarity
messages: Belongs to the FAM178 family.

419612:PRKD2
gene id: 419612:PRKD2
uniprot id: A0A8B8TH97
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

419612:LOC116669148
gene id: 419612:LOC116669148
uniprot id: A0A8B8UHS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MBTPS2
gene id: 419612:MBTPS2
uniprot id: A0A8B8SPS5
names: Similarity
messages: Belongs to the peptidase M50A family.

419612:LOC102506396
gene id: 419612:LOC102506396
uniprot id: A0A8B8SK70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMN family.
messages: Cajal body
messages: Perikaryon
messages: Z line
messages: gem
messages: neuron projection

419612:LOC102507268
gene id: 419612:LOC102507268
uniprot id: A0A8B6YLQ4
uniprot id: A0A8B7KBX1
names: Similarity
messages: Belongs to the multicopper oxidase family.

419612:SERPINB6
gene id: 419612:SERPINB6
uniprot id: A0A8B8RK26
uniprot id: S9XJK0
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

419612:LOC102507575
gene id: 419612:LOC102507575
uniprot id: A0A8B7K509
names: Subcellular Location Annotation
messages: Membrane

419612:RIOX2
gene id: 419612:RIOX2
uniprot id: A0A8B8TU33
uniprot id: A0A8B8TU49
uniprot id: A0A8B8TU61
uniprot id: A0A8B8TV84
uniprot id: A0A8B8TVA3
uniprot id: A0A8B8TVA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

419612:POPDC3
gene id: 419612:POPDC3
uniprot id: A0A8B7KEV9
names: Similarity
messages: Belongs to the popeye family.

419612:CDK16
gene id: 419612:CDK16
uniprot id: A0A8B8SPB8
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:UCK2
gene id: 419612:UCK2
uniprot id: A0A8B8RP49
uniprot id: A0A8B8RPK9
uniprot id: A0A8B8RR70
names: Similarity
messages: Belongs to the uridine kinase family.

419612:PRKCA
gene id: 419612:PRKCA
uniprot id: A0A8B8R4J6
uniprot id: A0A8B8R6S8
uniprot id: A0A8B8R793
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

419612:ATG13
gene id: 419612:ATG13
uniprot id: A0A8B7K7B4
uniprot id: A0A8B7K7E2
uniprot id: A0A8B7K7W2
uniprot id: A0A8B8TQA0
uniprot id: A0A8B8TQA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

419612:CBL
gene id: 419612:CBL
uniprot id: A0A8B8SGL2
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

419612:LHX6
gene id: 419612:LHX6
uniprot id: A0A8B8SW84
uniprot id: A0A8B8SW96
uniprot id: A0A8B8SWP0
uniprot id: A0A8B8SXB1
uniprot id: A0A8B8SXB6
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102504527
gene id: 419612:LOC102504527
uniprot id: S9YPJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

419612:STMN4
gene id: 419612:STMN4
uniprot id: A0A8B6YQ91
uniprot id: A0A8B7KFX5
uniprot id: A0A8B8SAJ1
names: Similarity
messages: Belongs to the stathmin family.

419612:STMN1
gene id: 419612:STMN1
uniprot id: A0A8B8UAU4
names: Similarity
messages: Belongs to the stathmin family.

419612:MARK3
gene id: 419612:MARK3
uniprot id: A0A8B8T8R3
uniprot id: A0A8B8T8R4
uniprot id: A0A8B8T8R8
uniprot id: A0A8B8T8R9
uniprot id: A0A8B8T8S3
uniprot id: A0A8B8T8V7
uniprot id: A0A8B8T8W2
uniprot id: A0A8B8T977
uniprot id: A0A8B8T982
uniprot id: A0A8B8T986
uniprot id: A0A8B8T992
uniprot id: A0A8B8T9Q8
uniprot id: A0A8B8T9R5
uniprot id: A0A8B8T9R9
uniprot id: A0A8B8T9S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

419612:TLCD3B
gene id: 419612:TLCD3B
uniprot id: A0A8B8REJ4
uniprot id: A0A8B8RER5
names: Subcellular Location Annotation
messages: Membrane

419612:LOC106728802
gene id: 419612:LOC106728802
uniprot id: A0A8B7K5S2
uniprot id: A0A8B8U0I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:NOL12
gene id: 419612:NOL12
uniprot id: A0A8B6Y6N5
uniprot id: A0A8B8U0J0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP17 family.
messages: Interacts with KIAA1191.
messages: nucleolus

419612:ITGB1
gene id: 419612:ITGB1
uniprot id: A0A8B8SHV0
uniprot id: A0A8B8SKB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: Recycling endosome
messages: focal adhesion
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

419612:DCAF10
gene id: 419612:DCAF10
uniprot id: A0A8B6YQ23
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

419612:GTF2H5
gene id: 419612:GTF2H5
uniprot id: A0A8B7K8F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

419612:ADRB3
gene id: 419612:ADRB3
uniprot id: A0A8B8S3U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
messages: Cell membrane
messages: Interacts with ARRDC3.
messages: Membrane

419612:BCAS2
gene id: 419612:BCAS2
uniprot id: A0A8B6YMT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

419612:TSPAN32
gene id: 419612:TSPAN32
uniprot id: A0A8B8TUR3
names: Subcellular Location Annotation
messages: Membrane

419612:RITA1
gene id: 419612:RITA1
uniprot id: A0A8B8SFE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RITA family.
messages: Cytoplasm
messages: Interacts with RBPJ/RBPSUH.
messages: Nucleus
messages: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

419612:KIF1B
gene id: 419612:KIF1B
uniprot id: A0A8B8U8Y2
uniprot id: A0A8B8U8Y7
uniprot id: A0A8B8U8Y9
uniprot id: A0A8B8U9R6
uniprot id: A0A8B8U9V8
uniprot id: A0A8B8U9W3
uniprot id: A0A8B8UA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

419612:CAPN3
gene id: 419612:CAPN3
uniprot id: A0A8B6Y9Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

419612:IL20RA
gene id: 419612:IL20RA
uniprot id: A0A8B8TF84
uniprot id: A0A8B8TF91
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102506530
gene id: 419612:LOC102506530
uniprot id: A0A8B8RL14
uniprot id: A0A8B8RL20
uniprot id: A0A8B8RL21
uniprot id: A0A8B8RLB7
uniprot id: A0A8B8RLC2
uniprot id: A0A8B8RMT3
uniprot id: A0A8B8RMT7
uniprot id: A0A8B8RN89
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:KRT77
gene id: 419612:KRT77
uniprot id: A0A8B8U330
names: Similarity
messages: Belongs to the intermediate filament family.

419612:POMGNT1
gene id: 419612:POMGNT1
uniprot id: A0A8B8U647
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

419612:LOC116658812
gene id: 419612:LOC116658812
uniprot id: S9XBX2
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:TM7SF2
gene id: 419612:TM7SF2
uniprot id: A0A8B6YER1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

419612:JUND
gene id: 419612:JUND
uniprot id: A0A8B8RU59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

419612:LOC102524473
gene id: 419612:LOC102524473
uniprot id: A0A8B8T423
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PACSIN1
gene id: 419612:PACSIN1
uniprot id: A0A8B8RLP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

419612:LOC102523164
gene id: 419612:LOC102523164
uniprot id: A0A8B6YGX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:HECTD2
gene id: 419612:HECTD2
uniprot id: A0A8B8TY40
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:AMER1
gene id: 419612:AMER1
uniprot id: S9WBQ6
names: Similarity
messages: Belongs to the Amer family.

419612:TFE3
gene id: 419612:TFE3
uniprot id: A0A8B8SKG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

419612:RORA
gene id: 419612:RORA
uniprot id: A0A8B8T3V0
uniprot id: A0A8B8T3V5
uniprot id: A0A8B8T469
uniprot id: A0A8B8T4M2
uniprot id: A0A8B8T4N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

419612:UBE2H
gene id: 419612:UBE2H
uniprot id: A0A8B8TAE6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:SERPINB1
gene id: 419612:SERPINB1
uniprot id: A0A8B7K413
names: Similarity
messages: Belongs to the serpin family.

419612:CDR2
gene id: 419612:CDR2
uniprot id: A0A8B8RFN6
names: Similarity
messages: Belongs to the CDR2 family.

419612:SLCO4A1
gene id: 419612:SLCO4A1
uniprot id: A0A8B8RHI6
uniprot id: A0A8B8RJG2
uniprot id: A0A8B8RJV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:CCR10
gene id: 419612:CCR10
uniprot id: A0A8B6Y7C4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:ATP2A2
gene id: 419612:ATP2A2
uniprot id: A0A8B8SCL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

419612:BTG1
gene id: 419612:BTG1
uniprot id: A0A8B8U5S5
names: Similarity
messages: Belongs to the BTG family.

419612:FOXI1
gene id: 419612:FOXI1
uniprot id: A0A8B8RUF4
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC116659221
gene id: 419612:LOC116659221
uniprot id: A0A8B8RXS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

419612:HDHD3
gene id: 419612:HDHD3
uniprot id: S9W4T1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

419612:PRDM8
gene id: 419612:PRDM8
uniprot id: A0A8B8R4L9
uniprot id: A0A8B8R4R2
names: Subcellular Location Annotation
messages: Nucleus

419612:FAM171A1
gene id: 419612:FAM171A1
uniprot id: A0A8B8SI40
uniprot id: A0A8B8SI41
uniprot id: A0A8B8SJ85
uniprot id: A0A8B8SJG7
uniprot id: A0A8B8SKK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

419612:GALNT15
gene id: 419612:GALNT15
uniprot id: A0A8B6YL20
uniprot id: A0A8B8TRN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

419612:MTHFD1
gene id: 419612:MTHFD1
uniprot id: A0A8B6Y9J8
uniprot id: A0A8B7K5P5
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

419612:YRDC
gene id: 419612:YRDC
uniprot id: A0A8B8UBC0
uniprot id: A0A8B8UCN6
names: Similarity
messages: Belongs to the SUA5 family.

419612:GRM2
gene id: 419612:GRM2
uniprot id: A0A8B8R8H6
uniprot id: A0A8B8RBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

419612:NFIB
gene id: 419612:NFIB
uniprot id: A0A8B6YNM3
uniprot id: A0A8B6YNU8
uniprot id: A0A8B6YNW2
uniprot id: A0A8B7KFZ3
uniprot id: A0A8B7KG18
uniprot id: A0A8B8STZ2
uniprot id: A0A8B8SUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

419612:POU5F1
gene id: 419612:POU5F1
uniprot id: A0A8B8RN69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

419612:IMPDH1
gene id: 419612:IMPDH1
uniprot id: A0A8B8TAE3
uniprot id: A0A8B8TAP5
uniprot id: A0A8B8TBD8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

419612:UGT8
gene id: 419612:UGT8
uniprot id: A0A8B8RJW7
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

419612:GAL3ST4
gene id: 419612:GAL3ST4
uniprot id: A0A8B6YDJ4
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

419612:GRIN2B
gene id: 419612:GRIN2B
uniprot id: A0A8B8SFJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

419612:NMUR1
gene id: 419612:NMUR1
uniprot id: A0A8B8T279
uniprot id: A0A8B8T2K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

419612:ALDH7A1
gene id: 419612:ALDH7A1
uniprot id: A0A8B6YLI1
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

419612:SFRP5
gene id: 419612:SFRP5
uniprot id: A0A8B8TXL0
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102521722
gene id: 419612:LOC102521722
uniprot id: A0A8B7KG76
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SLC5A2
gene id: 419612:SLC5A2
uniprot id: A0A8B6YCV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

419612:LOC102511833
gene id: 419612:LOC102511833
uniprot id: A0A8B8SP52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

419612:MTR
gene id: 419612:MTR
uniprot id: A0A8B8TZS2
uniprot id: A0A8B8TZS4
uniprot id: A0A8B8U0T0
uniprot id: A0A8B8U125
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
messages: Cytoplasm
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

419612:TPD52L3
gene id: 419612:TPD52L3
uniprot id: A0A8B6YTB8
names: Similarity
messages: Belongs to the TPD52 family.

419612:PDF
gene id: 419612:PDF
uniprot id: A0A8B6YBM2
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.

419612:MCMBP
gene id: 419612:MCMBP
uniprot id: A0A8B8TWJ1
uniprot id: A0A8B8TXX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

419612:ACSM5
gene id: 419612:ACSM5
uniprot id: A0A8B6YA21
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

419612:PFKFB3
gene id: 419612:PFKFB3
uniprot id: A0A8B8SHY1
uniprot id: A0A8B8SHY2
uniprot id: A0A8B8SHY5
uniprot id: A0A8B8SJ18
uniprot id: A0A8B8SJ23
uniprot id: A0A8B8SJ92
uniprot id: A0A8B8SJ98
uniprot id: A0A8B8SKE8
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

419612:MMP28
gene id: 419612:MMP28
uniprot id: A0A8B8UHU6
uniprot id: A0A8B8UJ49
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

419612:GLI3
gene id: 419612:GLI3
uniprot id: A0A8B8TD68
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

419612:LOC102511435
gene id: 419612:LOC102511435
uniprot id: S9X942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

419612:MSH4
gene id: 419612:MSH4
uniprot id: A0A8B6YN98
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

419612:KDM1B
gene id: 419612:KDM1B
uniprot id: A0A8B8RKI0
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

419612:FAM167A
gene id: 419612:FAM167A
uniprot id: A0A8B8S900
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

419612:SOSTDC1
gene id: 419612:SOSTDC1
uniprot id: S9XVU8
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MCM9
gene id: 419612:MCM9
uniprot id: A0A8B8TEK9
uniprot id: A0A8B8TFX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

419612:OSBP
gene id: 419612:OSBP
uniprot id: A0A8B8TQT0
names: Similarity
messages: Belongs to the OSBP family.

419612:LOC102517478
gene id: 419612:LOC102517478
uniprot id: A0A8B6Y8L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ADAM2
gene id: 419612:ADAM2
uniprot id: A0A8B8S279
uniprot id: A0A8B8S288
uniprot id: A0A8B8S3Z9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:DKK4
gene id: 419612:DKK4
uniprot id: A0A8B6YIZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

419612:NT5DC1
gene id: 419612:NT5DC1
uniprot id: A0A8B8TEH7
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

419612:NLN
gene id: 419612:NLN
uniprot id: A0A8B8SGS1
uniprot id: A0A8B8SGT1
uniprot id: A0A8B8SGX1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

419612:AVPR1B
gene id: 419612:AVPR1B
uniprot id: A0A8B8RZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

419612:SP4
gene id: 419612:SP4
uniprot id: A0A8B8TC99
names: Subcellular Location Annotation
messages: Nucleus

419612:LCN6
gene id: 419612:LCN6
uniprot id: A0A8B8ST55
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

419612:PCLAF
gene id: 419612:PCLAF
uniprot id: A0A8B6YFX8
uniprot id: A0A8B8T3K9
uniprot id: A0A8B8T4C5
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

419612:ZDHHC1
gene id: 419612:ZDHHC1
uniprot id: A0A8B8TJK1
uniprot id: A0A8B8TJK4
uniprot id: A0A8B8TJK6
uniprot id: A0A8B8TJL0
uniprot id: A0A8B8TJL4
uniprot id: A0A8B8TJM3
uniprot id: A0A8B8TJT8
uniprot id: A0A8B8TJU3
uniprot id: A0A8B8TJV4
uniprot id: A0A8B8TKU6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

419612:ACOT8
gene id: 419612:ACOT8
uniprot id: A0A8B6YI13
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

419612:MRPL14
gene id: 419612:MRPL14
uniprot id: A0A8B8RMA0
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

419612:TMEM45B
gene id: 419612:TMEM45B
uniprot id: A0A8B6YD29
uniprot id: A0A8B8SF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

419612:LAMB1
gene id: 419612:LAMB1
uniprot id: A0A8B8TD81
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

419612:TUBB
gene id: 419612:TUBB
uniprot id: A0A8B7KFR2
uniprot id: S9WJD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

419612:PLAC1
gene id: 419612:PLAC1
uniprot id: S9XP74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLAC1 family.
messages: Secreted

419612:ZKSCAN5
gene id: 419612:ZKSCAN5
uniprot id: A0A8B8RCF2
names: Subcellular Location Annotation
messages: Nucleus

419612:TRMT44
gene id: 419612:TRMT44
uniprot id: A0A8B8U485
uniprot id: A0A8B8U4P8
uniprot id: A0A8B8U4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm
messages: Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.

419612:ANKRD34B
gene id: 419612:ANKRD34B
uniprot id: S9Y6C8
names: Similarity
messages: Belongs to the ANKRD34 family.

419612:EIF1AD
gene id: 419612:EIF1AD
uniprot id: T0MH25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EIF1AD family.
messages: Interacts with GAPDH and STAT1.
messages: Plays a role into cellular response to oxidative stress. Decreases cell proliferation.

419612:RUVBL2
gene id: 419612:RUVBL2
uniprot id: A0A8B6Y5K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

419612:TAGLN2
gene id: 419612:TAGLN2
uniprot id: S9YE05
names: Similarity
messages: Belongs to the calponin family.

419612:USP37
gene id: 419612:USP37
uniprot id: A0A8B6YLD5
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

419612:LOC102523571
gene id: 419612:LOC102523571
uniprot id: A0A8B8RLD6
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

419612:PKIB
gene id: 419612:PKIB
uniprot id: A0A8B7KDD0
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

419612:HSBP1
gene id: 419612:HSBP1
uniprot id: A0A8B7K9B9
names: Similarity
messages: Belongs to the HSBP1 family.

419612:LOC102513679
gene id: 419612:LOC102513679
uniprot id: S9XPW5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SDHD
gene id: 419612:SDHD
uniprot id: A0A8B6Y6D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

419612:LRP6
gene id: 419612:LRP6
uniprot id: A0A8B8SFW0
uniprot id: A0A8B8SFW1
uniprot id: A0A8B8SIG6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:GPAT3
gene id: 419612:GPAT3
uniprot id: A0A8B8UJX3
uniprot id: A0A8B8UJY8
uniprot id: A0A8B8UKB9
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

419612:SLC9A3R2
gene id: 419612:SLC9A3R2
uniprot id: A0A8B6Y7J5
uniprot id: A0A8B8RDK1
uniprot id: A0A8B8RG37
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

419612:CBFB
gene id: 419612:CBFB
uniprot id: A0A8B8TJG1
uniprot id: A0A8B8TJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

419612:LOC102521012
gene id: 419612:LOC102521012
uniprot id: A0A8B8RH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

419612:DCST1
gene id: 419612:DCST1
uniprot id: A0A8B8RS38
names: Subcellular Location Annotation
messages: Membrane

419612:ANTXR2
gene id: 419612:ANTXR2
uniprot id: A0A8B6YP78
uniprot id: A0A8B8R4V1
uniprot id: A0A8B8R527
uniprot id: A0A8B8R545
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

419612:MLF2
gene id: 419612:MLF2
uniprot id: A0A8B8SH79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

419612:SERPINB10
gene id: 419612:SERPINB10
uniprot id: A0A8B6YMI7
uniprot id: A0A8B8S845
uniprot id: A0A8B8S9D8
names: Similarity
messages: Belongs to the serpin family.

419612:PGBD1
gene id: 419612:PGBD1
uniprot id: A0A8B8RMT1
uniprot id: A0A8B8RN46
uniprot id: A0A8B8RPH7
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102524502
gene id: 419612:LOC102524502
uniprot id: A0A8B6YNB0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:LOC102507365
gene id: 419612:LOC102507365
uniprot id: A0A8B8SJD5
names: Subcellular Location Annotation
messages: cytosol

419612:FXR1
gene id: 419612:FXR1
uniprot id: A0A8B8TBD5
uniprot id: A0A8B8TBE2
uniprot id: A0A8B8TBF1
uniprot id: A0A8B8TBG4
uniprot id: A0A8B8TBL4
uniprot id: A0A8B8TBT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule
messages: Nucleus envelope
messages: Postsynapse
messages: Synapse
messages: dendritic spine

419612:UCMA
gene id: 419612:UCMA
uniprot id: A0A8B8SIH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

419612:LOC106729226
gene id: 419612:LOC106729226
uniprot id: A0A8B8TSB8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

419612:LPAR1
gene id: 419612:LPAR1
uniprot id: A0A8B8SWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

419612:POLR2G
gene id: 419612:POLR2G
uniprot id: A0A8B6YE11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

419612:TCFL5
gene id: 419612:TCFL5
uniprot id: A0A8B8RHK6
uniprot id: A0A8B8RJG8
names: Subcellular Location Annotation
messages: Nucleus

419612:TAFA3
gene id: 419612:TAFA3
uniprot id: A0A8B6YDQ9
names: Similarity
messages: Belongs to the TAFA family.

419612:NQO2
gene id: 419612:NQO2
uniprot id: A0A8B8RK28
uniprot id: A0A8B8RK37
uniprot id: A0A8B8RKF0
uniprot id: A0A8B8RLW3
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

419612:EIF4E3
gene id: 419612:EIF4E3
uniprot id: A0A8B8R7J2
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

419612:LOC102514049
gene id: 419612:LOC102514049
uniprot id: A0A8B6Y9T5
names: Similarity
messages: Belongs to the intermediate filament family.

419612:AP3S2
gene id: 419612:AP3S2
uniprot id: A0A8B6YMD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

419612:EIF5A2
gene id: 419612:EIF5A2
uniprot id: A0A8B8TDJ3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

419612:LOC102513925
gene id: 419612:LOC102513925
uniprot id: A0A8B8T1W1
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:TOP2B
gene id: 419612:TOP2B
uniprot id: A0A8B8TPW2
uniprot id: A0A8B8TPX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

419612:PUSL1
gene id: 419612:PUSL1
uniprot id: A0A8B8U976
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

419612:E2F1
gene id: 419612:E2F1
uniprot id: A0A8B8RJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

419612:LOC102521772
gene id: 419612:LOC102521772
uniprot id: A0A8B8S9S5
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MED12L
gene id: 419612:MED12L
uniprot id: A0A8B8TK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

419612:FRAT2
gene id: 419612:FRAT2
uniprot id: A0A8B8TYP2
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

419612:CPA3
gene id: 419612:CPA3
uniprot id: A0A8B6YHS8
names: Similarity
messages: Belongs to the peptidase M14 family.

419612:LOC102514003
gene id: 419612:LOC102514003
uniprot id: A0A8B6YJ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

419612:DAG1
gene id: 419612:DAG1
uniprot id: A0A8B8R8U0
uniprot id: T0MC92
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

419612:CALY
gene id: 419612:CALY
uniprot id: A0A8B8TX32
uniprot id: A0A8B8TXD8
names: Similarity
messages: Belongs to the NSG family.

419612:LOC106728624
gene id: 419612:LOC106728624
uniprot id: A0A8B7K4C7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

419612:NHSL2
gene id: 419612:NHSL2
uniprot id: A0A8B8SMC9
uniprot id: A0A8B8SMD6
uniprot id: A0A8B8SNF0
uniprot id: A0A8B8SNF5
uniprot id: A0A8B8SNQ1
uniprot id: A0A8B8SNQ7
uniprot id: A0A8B8SNR2
uniprot id: A0A8B8SPJ6
uniprot id: A0A8B8SPK2
names: Similarity
messages: Belongs to the NHS family.

419612:SLC17A5
gene id: 419612:SLC17A5
uniprot id: A0A8B8RDZ5
uniprot id: A0A8B8RE60
uniprot id: A0A8B8RG11
names: Subcellular Location Annotation
messages: Membrane

419612:C10H11orf58
gene id: 419612:C10H11orf58
uniprot id: A0A8B8TRC8
names: Similarity
messages: Belongs to the SMAP family.

419612:PPRC1
gene id: 419612:PPRC1
uniprot id: A0A8B6YDT7
uniprot id: A0A8B7K8U2
uniprot id: A0A8B7K8V3
uniprot id: A0A8B7K9E5
uniprot id: A0A8B8TX95
uniprot id: A0A8B8TYC2
names: Subcellular Location Annotation
messages: Nucleus

419612:NHSL1
gene id: 419612:NHSL1
uniprot id: A0A8B8TGM6
names: Similarity
messages: Belongs to the NHS family.

419612:DIP2C
gene id: 419612:DIP2C
uniprot id: A0A8B8SID9
names: Similarity
messages: Belongs to the DIP2 family.

419612:NUDT21
gene id: 419612:NUDT21
uniprot id: A0A8B6YC94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

419612:CDCA7
gene id: 419612:CDCA7
uniprot id: A0A8B8SZZ8
uniprot id: A0A8B8T001
uniprot id: A0A8B8T0H2
uniprot id: A0A8B8T0X9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

419612:LOC116667145
gene id: 419612:LOC116667145
uniprot id: A0A8B8TYE9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

419612:THOC5
gene id: 419612:THOC5
uniprot id: A0A8B6YBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

419612:SYN3
gene id: 419612:SYN3
uniprot id: A0A8B8U3V3
names: Similarity
messages: Belongs to the synapsin family.

419612:NKX6-1
gene id: 419612:NKX6-1
uniprot id: A0A8B8UJX6
names: Subcellular Location Annotation
messages: Nucleus

419612:SESN1
gene id: 419612:SESN1
uniprot id: A0A8B6YHW2
uniprot id: A0A8B6YHW3
uniprot id: A0A8B7KBP4
uniprot id: A0A8B7KC14
uniprot id: A0A8B7KDT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

419612:MEGF9
gene id: 419612:MEGF9
uniprot id: A0A8B8SVV0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC116661880
gene id: 419612:LOC116661880
uniprot id: A0A8B8SK34
names: Similarity
messages: Belongs to the histone H2B family.

419612:LOC102504945
gene id: 419612:LOC102504945
uniprot id: S9XSR2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:KIF20B
gene id: 419612:KIF20B
uniprot id: A0A8B7K9U1
uniprot id: A0A8B8TY51
uniprot id: A0A8B8TY52
uniprot id: A0A8B8TY58
uniprot id: A0A8B8TZ52
uniprot id: A0A8B8TZ57
uniprot id: A0A8B8TZG8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:EIF4A1
gene id: 419612:EIF4A1
uniprot id: A0A8B6Y7P9
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

419612:LOC102504585
gene id: 419612:LOC102504585
uniprot id: A0A8B6YID0
uniprot id: A0A8B8TWN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

419612:MID1IP1
gene id: 419612:MID1IP1
uniprot id: A0A8B8SLR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

419612:TMEM87A
gene id: 419612:TMEM87A
uniprot id: A0A8B6YE08
uniprot id: A0A8B7K637
uniprot id: A0A8B7K6F0
uniprot id: A0A8B8T4W3
uniprot id: A0A8B8T4W7
uniprot id: A0A8B8T4W8
uniprot id: A0A8B8T571
uniprot id: A0A8B8T5L1
uniprot id: A0A8B8T5Q7
names: Subcellular Location Annotation
messages: Membrane

419612:CAMK2N1
gene id: 419612:CAMK2N1
uniprot id: T0M842
names: Similarity
messages: Belongs to the CAMK2N family.

419612:KCNH3
gene id: 419612:KCNH3
uniprot id: A0A8B7K7H3
uniprot id: A0A8B8U2M0
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

419612:FNIP1
gene id: 419612:FNIP1
uniprot id: A0A8B8SQW1
uniprot id: A0A8B8SS03
uniprot id: A0A8B8SST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

419612:CACFD1
gene id: 419612:CACFD1
uniprot id: A0A8B8SXK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

419612:UST
gene id: 419612:UST
uniprot id: A0A8B8TFJ4
uniprot id: A0A8B8TGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:NDUFA2
gene id: 419612:NDUFA2
uniprot id: S9YRE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

419612:DDX18
gene id: 419612:DDX18
uniprot id: A0A8B7KEL6
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

419612:LOC102515772
gene id: 419612:LOC102515772
uniprot id: A0A8B8RPX9
names: Similarity
messages: Belongs to the histone H3 family.

419612:CLTB
gene id: 419612:CLTB
uniprot id: A0A8B8RSL6
uniprot id: A0A8B8RTH3
uniprot id: A0A8B8RU83
uniprot id: A0A8B8RU88
uniprot id: A0A8B8RUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

419612:HERC4
gene id: 419612:HERC4
uniprot id: A0A8B8TYL6
uniprot id: A0A8B8TYN6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:CRTC1
gene id: 419612:CRTC1
uniprot id: A0A8B8RT23
uniprot id: A0A8B8RT27
uniprot id: A0A8B8RT28
uniprot id: A0A8B8RT32
uniprot id: A0A8B8RU02
uniprot id: A0A8B8RU07
uniprot id: A0A8B8RUP2
uniprot id: A0A8B8RUP6
uniprot id: A0A8B8RV01
uniprot id: A0A8B8RV06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

419612:TSPAN12
gene id: 419612:TSPAN12
uniprot id: A0A8B8TBK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:MYOZ3
gene id: 419612:MYOZ3
uniprot id: A0A8B7KHB4
names: Similarity
messages: Belongs to the myozenin family.

419612:GOLT1B
gene id: 419612:GOLT1B
uniprot id: A0A8B8SF38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

419612:SPICE1
gene id: 419612:SPICE1
uniprot id: A0A8B6Y7Y0
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CEP120.
messages: centriole
messages: spindle

419612:CCN2
gene id: 419612:CCN2
uniprot id: A0A8B8TF21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

419612:PLPP1
gene id: 419612:PLPP1
uniprot id: A0A8B8SD83
uniprot id: A0A8B8SD89
uniprot id: A0A8B8SEI8
uniprot id: A0A8B8SFR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

419612:RPL27
gene id: 419612:RPL27
uniprot id: A0A8B6YAW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

419612:KCND3
gene id: 419612:KCND3
uniprot id: A0A8B8TLV3
uniprot id: A0A8B8TLV7
uniprot id: A0A8B8TM82
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

419612:CFDP1
gene id: 419612:CFDP1
uniprot id: A0A8B8TK80
uniprot id: A0A8B8TLG2
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

419612:MGP
gene id: 419612:MGP
uniprot id: A0A8B6YQQ8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
messages: Requires vitamin K-dependent gamma-carboxylation for its function.
messages: Secreted

419612:LECT2
gene id: 419612:LECT2
uniprot id: A0A8B6YEQ4
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

419612:EDA2R
gene id: 419612:EDA2R
uniprot id: A0A8B8SMI4
uniprot id: A0A8B8SNN8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:TAF8
gene id: 419612:TAF8
uniprot id: A0A8B8RNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

419612:CSNK2B
gene id: 419612:CSNK2B
uniprot id: A0A8B8RMN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

419612:LOC102506367
gene id: 419612:LOC102506367
uniprot id: A0A8B6YD88
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ATP6V0B
gene id: 419612:ATP6V0B
uniprot id: A0A8B8U5W0
uniprot id: A0A8B8U6Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

419612:EFNB1
gene id: 419612:EFNB1
uniprot id: A0A8B8SKW5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:YWHAH
gene id: 419612:YWHAH
uniprot id: A0A8B8SCV1
names: Similarity
messages: Belongs to the 14-3-3 family.

419612:TACC1
gene id: 419612:TACC1
uniprot id: A0A8B6YE71
uniprot id: A0A8B8S2A3
uniprot id: A0A8B8S2A5
uniprot id: A0A8B8S3M6
uniprot id: A0A8B8S3N1
uniprot id: A0A8B8S3W7
uniprot id: A0A8B8S421
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

419612:PELI1
gene id: 419612:PELI1
uniprot id: A0A8B8UG57
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

419612:TUB
gene id: 419612:TUB
uniprot id: A0A8B8TRS6
uniprot id: A0A8B8TRS8
uniprot id: A0A8B8TRT0
uniprot id: A0A8B8TRT1
uniprot id: A0A8B8TRT4
uniprot id: A0A8B8TRT5
uniprot id: A0A8B8TSM9
uniprot id: A0A8B8TSN4
uniprot id: A0A8B8TSW8
uniprot id: A0A8B8TSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

419612:PSD
gene id: 419612:PSD
uniprot id: A0A8B8TYL1
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

419612:SCN3B
gene id: 419612:SCN3B
uniprot id: A0A8B7K6Y0
uniprot id: S9YKF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

419612:APP
gene id: 419612:APP
uniprot id: A0A8B8SRK8
uniprot id: A0A8B8SRM0
uniprot id: A0A8B8SRM8
uniprot id: A0A8B8SRP3
uniprot id: A0A8B8SSC4
uniprot id: A0A8B8SSQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Endosome
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Golgi apparatus
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
messages: Nucleus
messages: Perikaryon
messages: Secreted
messages: The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis.
messages: Vesicle
messages: clathrin-coated pit
messages: growth cone

419612:IAH1
gene id: 419612:IAH1
uniprot id: A0A8B8UE80
uniprot id: A0A8B8UEY7
uniprot id: A0A8B8UF09
uniprot id: A0A8B8UFM2
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

419612:PSME2
gene id: 419612:PSME2
uniprot id: A0A8B6Y8V5
names: Similarity
messages: Belongs to the PA28 family.

419612:INPP5K
gene id: 419612:INPP5K
uniprot id: A0A8B6YFM5
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

419612:PRDX1
gene id: 419612:PRDX1
uniprot id: A0A8B8U629
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

419612:CES5A
gene id: 419612:CES5A
uniprot id: A0A8B7K6M5
uniprot id: A0A8B7K8W9
uniprot id: A0A8B8TJ23
uniprot id: A0A8B8TJ28
uniprot id: A0A8B8TJ29
uniprot id: A0A8B8TJ93
uniprot id: A0A8B8TJ99
uniprot id: A0A8B8TKA6
uniprot id: A0A8B8TKB0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

419612:MFAP2
gene id: 419612:MFAP2
uniprot id: A0A8B8UA41
uniprot id: A0A8B8UA82
uniprot id: A0A8B8UAJ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:GFRAL
gene id: 419612:GFRAL
uniprot id: A0A8B6YDM6
names: Similarity
messages: Belongs to the GDNFR family.

419612:SMARCAL1
gene id: 419612:SMARCAL1
uniprot id: A0A8B8T1S6
uniprot id: A0A8B8T1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

419612:ZFYVE16
gene id: 419612:ZFYVE16
uniprot id: A0A8B6YHC2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

419612:AAR2
gene id: 419612:AAR2
uniprot id: A0A8B6YIY9
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

419612:LOC102517330
gene id: 419612:LOC102517330
uniprot id: A0A8B8SIJ3
names: Subcellular Location Annotation
messages: Nucleus

419612:EIF5B
gene id: 419612:EIF5B
uniprot id: A0A8B8S5Y4
uniprot id: A0A8B8S809
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

419612:RAB32
gene id: 419612:RAB32
uniprot id: A0A8B6YHA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

419612:GUK1
gene id: 419612:GUK1
uniprot id: A0A8B8SSR6
uniprot id: A0A8B8SSU1
uniprot id: A0A8B8SSU6
uniprot id: A0A8B8STC3
uniprot id: A0A8B8STP9
uniprot id: A0A8B8SUF3
names: Similarity
messages: Belongs to the guanylate kinase family.

419612:NLK
gene id: 419612:NLK
uniprot id: A0A8B8R6C5
uniprot id: A0A8B8R933
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

419612:DAZAP2
gene id: 419612:DAZAP2
uniprot id: A0A8B8U2W5
uniprot id: A0A8B8U3D8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

419612:ACP1
gene id: 419612:ACP1
uniprot id: A0A8B7KD22
uniprot id: A0A8B8UER6
uniprot id: A0A8B8UFF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

419612:MED29
gene id: 419612:MED29
uniprot id: S9XCC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 29 family.
messages: Nucleus

419612:HMGCL
gene id: 419612:HMGCL
uniprot id: A0A8B6YAT6
uniprot id: A0A8B7K8I8
uniprot id: A0A8B8U9T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

419612:TRPM5
gene id: 419612:TRPM5
uniprot id: A0A8B8TUR5
uniprot id: A0A8B8TVU0
uniprot id: A0A8B8TW03
names: Subcellular Location Annotation
messages: Membrane

419612:DBX1
gene id: 419612:DBX1
uniprot id: A0A8B8TWP3
names: Subcellular Location Annotation
messages: Nucleus

419612:DPY19L2
gene id: 419612:DPY19L2
uniprot id: A0A8B6YLK1
uniprot id: A0A8B8TBI7
uniprot id: A0A8B8TBW0
uniprot id: A0A8B8TCR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

419612:EML1
gene id: 419612:EML1
uniprot id: A0A8B8T8D6
uniprot id: A0A8B8T8E3
uniprot id: A0A8B8T8I9
uniprot id: A0A8B8T8W4
names: Similarity
messages: Belongs to the WD repeat EMAP family.

419612:LOC102522446
gene id: 419612:LOC102522446
uniprot id: A0A8B8SCJ0
names: Similarity
messages: Belongs to the RIMBP family.

419612:COPS9
gene id: 419612:COPS9
uniprot id: A0A8B8T358
names: Similarity
messages: Belongs to the CSN9 family.

419612:MRPL44
gene id: 419612:MRPL44
uniprot id: A0A8B8T2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

419612:LOC102520281
gene id: 419612:LOC102520281
uniprot id: A0A8B6YH80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CORO1C
gene id: 419612:CORO1C
uniprot id: A0A8B8SCG3
names: Similarity
messages: Belongs to the WD repeat coronin family.

419612:SLC7A6
gene id: 419612:SLC7A6
uniprot id: A0A8B6YCZ1
uniprot id: A0A8B8TJS9
names: Subcellular Location Annotation
messages: Membrane

419612:SCG2
gene id: 419612:SCG2
uniprot id: S9WLS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Interacts with Secretogranin III/SCG3.
messages: Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
messages: Secreted

419612:TAF6
gene id: 419612:TAF6
uniprot id: A0A8B6YC80
uniprot id: A0A8B7K9S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

419612:HHATL
gene id: 419612:HHATL
uniprot id: A0A8B8RAH1
uniprot id: A0A8B8RAH6
uniprot id: A0A8B8RD81
names: Subcellular Location Annotation
messages: Membrane

419612:MRPL18
gene id: 419612:MRPL18
uniprot id: A0A8B6YE64
uniprot id: A0A8B7K676
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

419612:MIXL1
gene id: 419612:MIXL1
uniprot id: A0A8B8RXF8
names: Subcellular Location Annotation
messages: Nucleus

419612:RPRD1B
gene id: 419612:RPRD1B
uniprot id: A0A8B6YJ63
uniprot id: A0A8B7KCI7
uniprot id: A0A8B8RK11
uniprot id: A0A8B8RLI1
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

419612:LOC102506682
gene id: 419612:LOC102506682
uniprot id: A0A8B6YAH8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:APCS
gene id: 419612:APCS
uniprot id: A0A8B6Y9P3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

419612:SBF2
gene id: 419612:SBF2
uniprot id: A0A8B8TRM7
uniprot id: A0A8B8TRM8
uniprot id: A0A8B8TRN4
uniprot id: A0A8B8TSR7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

419612:LOC102520661
gene id: 419612:LOC102520661
uniprot id: A0A8B6Y9P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TAS2R10
gene id: 419612:TAS2R10
uniprot id: A0A8B8SH03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

419612:LOC102520321
gene id: 419612:LOC102520321
uniprot id: A0A8B8UGK6
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:ITGB3
gene id: 419612:ITGB3
uniprot id: A0A8B8R4Y7
uniprot id: A0A8B8R556
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: Recycling endosome
messages: focal adhesion
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

419612:LOC116658044
gene id: 419612:LOC116658044
uniprot id: A0A8B8RK76
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

419612:ACAD11
gene id: 419612:ACAD11
uniprot id: A0A8B8TPF5
uniprot id: A0A8B8TPH2
uniprot id: A0A8B8TQ61
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

419612:LOC102504739
gene id: 419612:LOC102504739
uniprot id: A0A8B6YBS3
uniprot id: A0A8B7K698
uniprot id: A0A8B7K6P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

419612:NOS1
gene id: 419612:NOS1
uniprot id: A0A8B8SAN3
uniprot id: A0A8B8SAN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

419612:ITK
gene id: 419612:ITK
uniprot id: A0A8B6Y7U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

419612:PDPR
gene id: 419612:PDPR
uniprot id: A0A8B8TK48
uniprot id: A0A8B8TK61
names: Similarity
messages: Belongs to the GcvT family.

419612:DTD2
gene id: 419612:DTD2
uniprot id: A0A8B6YMS1
names: Similarity
messages: Belongs to the DTD family.

419612:AGAP2
gene id: 419612:AGAP2
uniprot id: A0A8B8U3F8
uniprot id: A0A8B8U3G0
uniprot id: A0A8B8U3G5
uniprot id: A0A8B8U443
uniprot id: A0A8B8U448
uniprot id: A0A8B8U4E8
uniprot id: A0A8B8U4F1
names: Similarity
messages: Belongs to the centaurin gamma-like family.

419612:LOC102513749
gene id: 419612:LOC102513749
uniprot id: A0A8B6YHL4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

419612:RRP1
gene id: 419612:RRP1
uniprot id: A0A8B8UBD7
uniprot id: A0A8B8UCE1
uniprot id: A0A8B8UD59
names: Similarity
messages: Belongs to the RRP1 family.

419612:ITIH1
gene id: 419612:ITIH1
uniprot id: A0A8B6YKG0
uniprot id: A0A8B8RAE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

419612:PDK3
gene id: 419612:PDK3
uniprot id: A0A8B6YNZ0
uniprot id: A0A8B8SNP0
uniprot id: A0A8B8SNZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

419612:MRPL47
gene id: 419612:MRPL47
uniprot id: A0A8B6YIK7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

419612:LOC106730987
gene id: 419612:LOC106730987
uniprot id: A0A8B8TUM1
uniprot id: A0A8B8TVW4
names: Similarity
messages: Belongs to the actin family.

419612:EXOC4
gene id: 419612:EXOC4
uniprot id: A0A8B8TAM9
uniprot id: A0A8B8TBN1
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

419612:DNTTIP1
gene id: 419612:DNTTIP1
uniprot id: A0A8B7KDY4
uniprot id: A0A8B8RGR0
names: Subcellular Location Annotation
messages: Nucleus

419612:GSDMD
gene id: 419612:GSDMD
uniprot id: A0A8B8S045
uniprot id: A0A8B8S1G6
uniprot id: A0A8B8S1Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

419612:CAPN11
gene id: 419612:CAPN11
uniprot id: A0A8B8RMK7
names: Similarity
messages: Belongs to the peptidase C2 family.

419612:SPDL1
gene id: 419612:SPDL1
uniprot id: A0A8B7KDJ0
uniprot id: A0A8B8RUF9
uniprot id: A0A8B8RUR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Spindly family.
messages: Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
messages: Nucleus
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
messages: centrosome
messages: kinetochore
messages: spindle pole

419612:CTSF
gene id: 419612:CTSF
uniprot id: A0A8B7K6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

419612:C10H11orf54
gene id: 419612:C10H11orf54
uniprot id: A0A8B7KBY1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

419612:LOC116656624
gene id: 419612:LOC116656624
uniprot id: A0A8B8SI04
names: Similarity
messages: Belongs to the aldo/keto reductase family.

419612:HOMER2
gene id: 419612:HOMER2
uniprot id: A0A8B8S6K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

419612:SLC39A5
gene id: 419612:SLC39A5
uniprot id: T0NJN9
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102520168
gene id: 419612:LOC102520168
uniprot id: A0A8B6YAY5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC116666381
gene id: 419612:LOC116666381
uniprot id: A0A8B8TQN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:DR1
gene id: 419612:DR1
uniprot id: S9WDN3
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

419612:PRORP
gene id: 419612:PRORP
uniprot id: A0A8B7KBV0
names: Similarity
messages: Belongs to the PPR family. P subfamily.

419612:LOC106731168
gene id: 419612:LOC106731168
uniprot id: A0A8B8U7R8
uniprot id: A0A8B8U8L2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

419612:ADGRE1
gene id: 419612:ADGRE1
uniprot id: A0A8B7K566
uniprot id: A0A8B7K5G7
uniprot id: A0A8B7K5K2
uniprot id: A0A8B7K7E6
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:FBXO48
gene id: 419612:FBXO48
uniprot id: A0A8B8UGX6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.
messages: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability. Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1. Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway. Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation.

419612:LOC102506002
gene id: 419612:LOC102506002
uniprot id: A0A8B6YKY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

419612:POLE2
gene id: 419612:POLE2
uniprot id: A0A8B8T6G1
uniprot id: A0A8B8T6H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus
messages: Participates in DNA repair and in chromosomal DNA replication.

419612:B9D2
gene id: 419612:B9D2
uniprot id: A0A8B6YK56
uniprot id: A0A8B7KEI6
names: Subcellular Location Annotation
messages: cilium basal body

419612:DUSP13
gene id: 419612:DUSP13
uniprot id: A0A8B7K8R4
uniprot id: A0A8B7K9C6
uniprot id: A0A8B8TZV9
uniprot id: A0A8B8TZW3
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

419612:ARG2
gene id: 419612:ARG2
uniprot id: A0A8B8T781
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

419612:SCTR
gene id: 419612:SCTR
uniprot id: A0A8B8SZ97
uniprot id: A0A8B8SZV4
names: Subcellular Location Annotation
messages: Membrane

419612:ZDHHC7
gene id: 419612:ZDHHC7
uniprot id: A0A8B8TLX8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

419612:LOC102514716
gene id: 419612:LOC102514716
uniprot id: A0A8B6YD87
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

419612:BCL2
gene id: 419612:BCL2
uniprot id: A0A8B8S8C3
uniprot id: A0A8B8S8D0
uniprot id: A0A8B8S9S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

419612:MZF1
gene id: 419612:MZF1
uniprot id: A0A8B8TM52
names: Subcellular Location Annotation
messages: Nucleus

419612:NR1H4
gene id: 419612:NR1H4
uniprot id: A0A8B6YN75
uniprot id: A0A8B6YRN3
uniprot id: A0A8B8U5I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

419612:LOC102512354
gene id: 419612:LOC102512354
uniprot id: S9W997
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LIG1
gene id: 419612:LIG1
uniprot id: A0A8B8TID7
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

419612:GK2
gene id: 419612:GK2
uniprot id: S9WL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

419612:CHMP4C
gene id: 419612:CHMP4C
uniprot id: S9W711
names: Similarity
messages: Belongs to the SNF7 family.

419612:TMEM201
gene id: 419612:TMEM201
uniprot id: A0A8B8U9P9
uniprot id: A0A8B8U9T9
uniprot id: A0A8B8UA26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

419612:RAB19
gene id: 419612:RAB19
uniprot id: A0A8B6YFZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

419612:PGPEP1
gene id: 419612:PGPEP1
uniprot id: A0A8B7KBR6
uniprot id: A0A8B8RT85
uniprot id: A0A8B8RU69
uniprot id: A0A8B8RUV1
uniprot id: A0A8B8RV56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

419612:LMF1
gene id: 419612:LMF1
uniprot id: A0A8B8REW0
uniprot id: A0A8B8REX1
uniprot id: A0A8B8RF33
uniprot id: A0A8B8RGV3
uniprot id: A0A8B8RHD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

419612:ANXA7
gene id: 419612:ANXA7
uniprot id: A0A8B7K8K0
uniprot id: A0A8B8S7M2
uniprot id: A0A8B8S8W1
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

419612:ACR
gene id: 419612:ACR
uniprot id: A0A8B8U2U0
names: Function
names: Similarity
names: Subunit
messages: Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
messages: Belongs to the peptidase S1 family.
messages: Heavy chain (catalytic) and a light chain linked by two disulfide bonds. Forms a heterodimer with SERPINA5.

419612:SHBG
gene id: 419612:SHBG
uniprot id: A0A8B6Y795
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:TMEM183A
gene id: 419612:TMEM183A
uniprot id: A0A8B6YDF2
uniprot id: A0A8B7K618
uniprot id: A0A8B8RXD3
uniprot id: A0A8B8RYP8
uniprot id: A0A8B8RZ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

419612:GOSR2
gene id: 419612:GOSR2
uniprot id: A0A8B6YSE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

419612:DACT1
gene id: 419612:DACT1
uniprot id: A0A8B8T7U2
names: Similarity
messages: Belongs to the dapper family.

419612:EVC2
gene id: 419612:EVC2
uniprot id: A0A8B8U4Y0
uniprot id: A0A8B8U4Z1
uniprot id: A0A8B8U4Z4
uniprot id: A0A8B8U523
uniprot id: A0A8B8U5V5
uniprot id: A0A8B8U5W4
uniprot id: A0A8B8U5X8
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

419612:POFUT1
gene id: 419612:POFUT1
uniprot id: A0A8B8RJ61
uniprot id: A0A8B8RKZ1
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

419612:E2F4
gene id: 419612:E2F4
uniprot id: A0A8B8TJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

419612:WDFY1
gene id: 419612:WDFY1
uniprot id: A0A8B8T1U1
uniprot id: A0A8B8T1U3
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

419612:PRUNE2
gene id: 419612:PRUNE2
uniprot id: A0A8B8SUI8
uniprot id: A0A8B8SUR0
uniprot id: A0A8B8SUX0
uniprot id: A0A8B8SVB8
uniprot id: A0A8B8SW12
uniprot id: A0A8B8SW19
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

419612:FOXD1
gene id: 419612:FOXD1
uniprot id: A0A8B8SJY9
names: Subcellular Location Annotation
messages: Nucleus

419612:ITIH3
gene id: 419612:ITIH3
uniprot id: A0A8B6YKJ1
uniprot id: A0A8B8R899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

419612:PER3
gene id: 419612:PER3
uniprot id: A0A8B8U8Q7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

419612:CCN5
gene id: 419612:CCN5
uniprot id: A0A8B7KFM8
uniprot id: A0A8B7KGV4
names: Similarity
messages: Belongs to the CCN family.

419612:LOC102507190
gene id: 419612:LOC102507190
uniprot id: A0A8B6YJC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ABCG5
gene id: 419612:ABCG5
uniprot id: A0A8B6YHD8
uniprot id: A0A8B8UG54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

419612:HS3ST6
gene id: 419612:HS3ST6
uniprot id: A0A8B8RDI4
uniprot id: A0A8B8RDP3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

419612:OPN5
gene id: 419612:OPN5
uniprot id: A0A8B6YPK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

419612:SRRD
gene id: 419612:SRRD
uniprot id: A0A8B8SB45
uniprot id: A0A8B8SCA7
names: Similarity
messages: Belongs to the SRR1 family.

419612:LOC102507701
gene id: 419612:LOC102507701
uniprot id: A0A8B8T7R0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

419612:LOC116669063
gene id: 419612:LOC116669063
uniprot id: A0A8B8UIA4
names: Similarity
messages: Belongs to the PPDPF family.

419612:SLC6A13
gene id: 419612:SLC6A13
uniprot id: A0A8B8SF59
uniprot id: A0A8B8SHS0
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

419612:LOC116668497
gene id: 419612:LOC116668497
uniprot id: A0A8B8UBE1
names: Similarity
messages: Belongs to the SecE/SEC61-gamma family.

419612:GRIK3
gene id: 419612:GRIK3
uniprot id: A0A8B8UB97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

419612:SETD6
gene id: 419612:SETD6
uniprot id: A0A8B8TKJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

419612:SVOP
gene id: 419612:SVOP
uniprot id: A0A8B6Y7Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

419612:KATNAL1
gene id: 419612:KATNAL1
uniprot id: A0A8B6YRD4
uniprot id: A0A8B8UCD7
uniprot id: A0A8B8UCD8
uniprot id: A0A8B8UDQ5
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Interacts with KATNB1 and KATNBL1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

419612:KEG61 p08
gene id: 419612:KEG61_p08
uniprot id: A6YAS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

419612:NLRP14
gene id: 419612:NLRP14
uniprot id: A0A8B8TRY3
names: Similarity
messages: Belongs to the NLRP family.

419612:CNPY2
gene id: 419612:CNPY2
uniprot id: A0A8B6YAY8
names: Similarity
messages: Belongs to the canopy family.

419612:PIGV
gene id: 419612:PIGV
uniprot id: A0A8B8UAY7
uniprot id: A0A8B8UBH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

419612:GPR32
gene id: 419612:GPR32
uniprot id: A0A8B8TLZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

419612:KDM4A
gene id: 419612:KDM4A
uniprot id: A0A8B6YA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

419612:DNAJC22
gene id: 419612:DNAJC22
uniprot id: A0A8B8U239
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane

419612:UBE2E1
gene id: 419612:UBE2E1
uniprot id: A0A8B8TR14
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:ELOVL7
gene id: 419612:ELOVL7
uniprot id: A0A8B8SEL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

419612:LOC102507383
gene id: 419612:LOC102507383
uniprot id: A0A8B8SH77
uniprot id: A0A8B8SJP9
names: Function
names: Subcellular Location Annotation
messages: As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking.
messages: centrosome
messages: cilium basal body

419612:RAD1
gene id: 419612:RAD1
uniprot id: A0A8B6YPA2
uniprot id: A0A8B8S938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

419612:ETS1
gene id: 419612:ETS1
uniprot id: A0A8B6YDY6
uniprot id: A0A8B7KA41
uniprot id: A0A8B8SE36
uniprot id: A0A8B8SF96
uniprot id: A0A8B8SFC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

419612:SLC26A8
gene id: 419612:SLC26A8
uniprot id: A0A8B8RLJ7
uniprot id: A0A8B8RLK2
uniprot id: A0A8B8RLK5
uniprot id: A0A8B8RLK9
uniprot id: A0A8B8RLV5
uniprot id: A0A8B8RNC3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:TSG101
gene id: 419612:TSG101
uniprot id: A0A8B8TR88
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

419612:GLIS2
gene id: 419612:GLIS2
uniprot id: A0A8B8RGC8
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

419612:NDUFS6
gene id: 419612:NDUFS6
uniprot id: A0A8B8S7J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

419612:DIABLO
gene id: 419612:DIABLO
uniprot id: A0A8B6Y9H2
names: Subcellular Location Annotation
messages: Mitochondrion

419612:FKRP
gene id: 419612:FKRP
uniprot id: A0A8B8THC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LicD transferase family.
messages: Golgi apparatus membrane

419612:MRPL51
gene id: 419612:MRPL51
uniprot id: S9XC12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.
messages: Mitochondrion

419612:UROD
gene id: 419612:UROD
uniprot id: A0A8B6YA83
uniprot id: A0A8B7K665
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

419612:FGF11
gene id: 419612:FGF11
uniprot id: A0A8B8UJ45
uniprot id: A0A8B8UJK8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

419612:LOC102513056
gene id: 419612:LOC102513056
uniprot id: A0A8B6YQY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

419612:XPNPEP2
gene id: 419612:XPNPEP2
uniprot id: A0A8B8SKN5
names: Similarity
messages: Belongs to the peptidase M24B family.

419612:BRD1
gene id: 419612:BRD1
uniprot id: A0A8B8U1F7
uniprot id: A0A8B8U1V5
uniprot id: A0A8B8U1W0
uniprot id: A0A8B8U2G8
uniprot id: A0A8B8U2P6
names: Subcellular Location Annotation
messages: Nucleus

419612:FBLN7
gene id: 419612:FBLN7
uniprot id: A0A8B8S7E0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MCF2L
gene id: 419612:MCF2L
uniprot id: A0A8B8UD24
uniprot id: A0A8B8UD30
uniprot id: A0A8B8UD34
uniprot id: A0A8B8UD35
uniprot id: A0A8B8UDT4
uniprot id: A0A8B8UDU3
uniprot id: A0A8B8UDU9
uniprot id: A0A8B8UDV3
uniprot id: A0A8B8UDW0
uniprot id: A0A8B8UEE5
uniprot id: A0A8B8UEF2
names: Subcellular Location Annotation
messages: Cytoplasm

419612:PHKG1
gene id: 419612:PHKG1
uniprot id: A0A8B8RG62
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

419612:MYO7A
gene id: 419612:MYO7A
uniprot id: A0A8B8TU04
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

419612:TRMT11
gene id: 419612:TRMT11
uniprot id: A0A8B6YJT0
uniprot id: A0A8B8TER6
uniprot id: A0A8B8TES0
uniprot id: A0A8B8TEW1
names: Function
names: Subunit
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
messages: Interacts with TRMT112.

419612:ASIC5
gene id: 419612:ASIC5
uniprot id: A0A8B6Y7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

419612:ACTBL2
gene id: 419612:ACTBL2
uniprot id: S9X844
names: Similarity
messages: Belongs to the actin family.

419612:FAM3C
gene id: 419612:FAM3C
uniprot id: A0A8B8TBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

419612:IPPK
gene id: 419612:IPPK
uniprot id: A0A8B8ST87
uniprot id: A0A8B8SUS5
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

419612:LOC116665386
gene id: 419612:LOC116665386
uniprot id: A0A8B8TES4
uniprot id: A0A8B8TET0
uniprot id: A0A8B8TG37
names: Similarity
messages: Belongs to the SCM family.

419612:MAP3K15
gene id: 419612:MAP3K15
uniprot id: A0A8B8SP82
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

419612:LOC102517471
gene id: 419612:LOC102517471
uniprot id: A0A8B6YHC9
uniprot id: A0A8B8TIX1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

419612:HK3
gene id: 419612:HK3
uniprot id: A0A8B8RSI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

419612:LANCL2
gene id: 419612:LANCL2
uniprot id: A0A8B7KEY8
uniprot id: A0A8B8SCD2
names: Similarity
messages: Belongs to the LanC-like protein family.

419612:ZDHHC2
gene id: 419612:ZDHHC2
uniprot id: A0A8B8S4H2
uniprot id: A0A8B8S4Q7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

419612:LOC102503863
gene id: 419612:LOC102503863
uniprot id: A0A8B7KEB3
uniprot id: A0A8B8UKC6
uniprot id: A0A8B8UKN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:CAPN6
gene id: 419612:CAPN6
uniprot id: A0A8B6YNR7
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102504425
gene id: 419612:LOC102504425
uniprot id: A0A8B8TD30
names: Similarity
messages: Belongs to the PRR23 family.

419612:BCDIN3D
gene id: 419612:BCDIN3D
uniprot id: S9YQJ4
names: Similarity
messages: Belongs to the methyltransferase superfamily.

419612:EMC7
gene id: 419612:EMC7
uniprot id: A0A8B8T5D8
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

419612:LOC116659234
gene id: 419612:LOC116659234
uniprot id: A0A8B8RYD5
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:CTNNA3
gene id: 419612:CTNNA3
uniprot id: A0A8B8TYK4
uniprot id: A0A8B8TYM6
uniprot id: A0A8B8TZW6
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

419612:SLC46A2
gene id: 419612:SLC46A2
uniprot id: A0A8B8SWA1
names: Subcellular Location Annotation
messages: Membrane

419612:EMC2
gene id: 419612:EMC2
uniprot id: A0A8B8S2C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

419612:ZFYVE27
gene id: 419612:ZFYVE27
uniprot id: A0A8B6YG22
uniprot id: A0A8B7KA79
uniprot id: A0A8B7KAX5
uniprot id: A0A8B8TXL1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

419612:LOC102517827
gene id: 419612:LOC102517827
uniprot id: A0A8B8UKX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

419612:SHMT1
gene id: 419612:SHMT1
uniprot id: A0A8B6Y7Y3
uniprot id: S9XJ98
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

419612:LBX1
gene id: 419612:LBX1
uniprot id: A0A8B8TXC2
names: Subcellular Location Annotation
messages: Nucleus

419612:AURKA
gene id: 419612:AURKA
uniprot id: A0A8B8RJ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

419612:GRIA2
gene id: 419612:GRIA2
uniprot id: A0A8B7K3R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

419612:MAP3K5
gene id: 419612:MAP3K5
uniprot id: A0A8B6YIU7
uniprot id: A0A8B8TF86
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

419612:KRR1
gene id: 419612:KRR1
uniprot id: A0A8B6YL51
uniprot id: A0A8B8U4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

419612:CHMP1B
gene id: 419612:CHMP1B
uniprot id: S9XWA7
names: Similarity
messages: Belongs to the SNF7 family.

419612:SHH
gene id: 419612:SHH
uniprot id: A0A8B8T9I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

419612:LOC116658727
gene id: 419612:LOC116658727
uniprot id: A0A8B8RQA7
uniprot id: A0A8B8RQV5
names: Similarity
messages: Belongs to the cornifin (SPRR) family.

419612:NIFK
gene id: 419612:NIFK
uniprot id: A0A8B8SZ83
uniprot id: A0A8B8SZ94
names: Subcellular Location Annotation
messages: nucleolus

419612:LOC102511007
gene id: 419612:LOC102511007
uniprot id: A0A8B8TM04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:ATXN10
gene id: 419612:ATXN10
uniprot id: A0A8B8U6D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
messages: perinuclear region

419612:CPNE7
gene id: 419612:CPNE7
uniprot id: A0A8B8RTN6
names: Similarity
messages: Belongs to the copine family.

419612:GHR
gene id: 419612:GHR
uniprot id: A0A8B8SB44
uniprot id: A0A8B8SDM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Cell membrane
messages: Membrane
messages: On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain. Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

419612:YWHAB
gene id: 419612:YWHAB
uniprot id: A0A8B8RGV6
names: Similarity
messages: Belongs to the 14-3-3 family.

419612:LOC102511374
gene id: 419612:LOC102511374
uniprot id: A0A8B8UJQ9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

419612:SAG
gene id: 419612:SAG
uniprot id: A0A8B6YMM3
names: Similarity
messages: Belongs to the arrestin family.

419612:HPS3
gene id: 419612:HPS3
uniprot id: A0A8B6YJ27
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: Cytoplasm
messages: Involved in early stages of melanosome biogenesis and maturation.

419612:MCOLN2
gene id: 419612:MCOLN2
uniprot id: A0A8B7KDS3
uniprot id: A0A8B8U7M5
uniprot id: A0A8B8U7M8
uniprot id: A0A8B8U8G9
uniprot id: A0A8B8U8M9
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

419612:FRAT1
gene id: 419612:FRAT1
uniprot id: A0A8B8TXN0
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

419612:KIF9
gene id: 419612:KIF9
uniprot id: A0A8B6Y9F5
uniprot id: A0A8B8R987
uniprot id: A0A8B8RC14
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:LOC102516739
gene id: 419612:LOC102516739
uniprot id: A0A8B7KFI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SGCZ
gene id: 419612:SGCZ
uniprot id: A0A8B8S2V1
uniprot id: A0A8B8S4N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

419612:LOC102518625
gene id: 419612:LOC102518625
uniprot id: A0A8B8SIJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

419612:NOTCH3
gene id: 419612:NOTCH3
uniprot id: A0A8B8RTK0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

419612:TTN
gene id: 419612:TTN
uniprot id: A0A8B8T071
uniprot id: A0A8B8T072
uniprot id: A0A8B8T076
uniprot id: A0A8B8T079
uniprot id: A0A8B8T084
uniprot id: A0A8B8T085
uniprot id: A0A8B8T091
uniprot id: A0A8B8T092
uniprot id: A0A8B8T096
uniprot id: A0A8B8T098
uniprot id: A0A8B8T0A2
uniprot id: A0A8B8T0A5
uniprot id: A0A8B8T0B0
uniprot id: A0A8B8T0B1
uniprot id: A0A8B8T0B6
uniprot id: A0A8B8T0B9
uniprot id: A0A8B8T0C3
uniprot id: A0A8B8T0C4
uniprot id: A0A8B8T0D1
uniprot id: A0A8B8T0D2
uniprot id: A0A8B8T0M5
uniprot id: A0A8B8T0N2
uniprot id: A0A8B8T0P0
uniprot id: A0A8B8T0P5
uniprot id: A0A8B8T0P7
uniprot id: A0A8B8T0Q2
uniprot id: A0A8B8T0Q5
uniprot id: A0A8B8T0Q9
uniprot id: A0A8B8T0R0
uniprot id: A0A8B8T0R5
uniprot id: A0A8B8T0R6
uniprot id: A0A8B8T0S0
uniprot id: A0A8B8T0S4
uniprot id: A0A8B8T0S8
uniprot id: A0A8B8T0S9
uniprot id: A0A8B8T0T3
uniprot id: A0A8B8T0T7
uniprot id: A0A8B8T0U3
uniprot id: A0A8B8T0V2
uniprot id: A0A8B8T0V9
uniprot id: A0A8B8T144
uniprot id: A0A8B8T151
uniprot id: A0A8B8T158
uniprot id: A0A8B8T165
uniprot id: A0A8B8T179
uniprot id: A0A8B8T188
uniprot id: A0A8B8T193
uniprot id: A0A8B8T1A0
uniprot id: A0A8B8T1A8
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

419612:FAM126B
gene id: 419612:FAM126B
uniprot id: A0A8B7KEL3
uniprot id: A0A8B8T126
uniprot id: A0A8B8T129
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

419612:SFRP4
gene id: 419612:SFRP4
uniprot id: A0A8B7KAC3
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:KIF5A
gene id: 419612:KIF5A
uniprot id: A0A8B6YHI5
uniprot id: A0A8B7K8H6
uniprot id: A0A8B8U3E0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:CD79A
gene id: 419612:CD79A
uniprot id: A0A8B6Y8F0
uniprot id: A0A8B7K3D0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:LOC102505559
gene id: 419612:LOC102505559
uniprot id: A0A8B8SD47
uniprot id: A0A8B8SD55
uniprot id: A0A8B8SD59
uniprot id: A0A8B8SEA8
uniprot id: A0A8B8SEF7
uniprot id: A0A8B8SEG3
uniprot id: A0A8B8SFM8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

419612:LOC102512530
gene id: 419612:LOC102512530
uniprot id: A0A8B6YH09
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:ARL3
gene id: 419612:ARL3
uniprot id: A0A8B8TX82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

419612:LOC102513405
gene id: 419612:LOC102513405
uniprot id: T0M5F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ACOD1
gene id: 419612:ACOD1
uniprot id: A0A8B8UC41
names: Similarity
messages: Belongs to the PrpD family.

419612:KDM4C
gene id: 419612:KDM4C
uniprot id: A0A8B7K4M1
uniprot id: A0A8B8SU62
uniprot id: A0A8B8SUW0
uniprot id: A0A8B8SVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

419612:OCLN
gene id: 419612:OCLN
uniprot id: A0A8B8SHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

419612:PJVK
gene id: 419612:PJVK
uniprot id: A0A8B6YP50
uniprot id: A0A8B8T066
uniprot id: A0A8B8T068
uniprot id: A0A8B8T0L6
names: Similarity
messages: Belongs to the gasdermin family.

419612:LOC102507156
gene id: 419612:LOC102507156
uniprot id: A0A8B6YPR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC106729279
gene id: 419612:LOC106729279
uniprot id: S9X3T8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:PPDPF
gene id: 419612:PPDPF
uniprot id: A0A8B8RK14
names: Similarity
messages: Belongs to the PPDPF family.

419612:APOA5
gene id: 419612:APOA5
uniprot id: A0A8B8SE97
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

419612:LOC102511079
gene id: 419612:LOC102511079
uniprot id: A0A8B6YPS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FXYD6
gene id: 419612:FXYD6
uniprot id: A0A8B8SEA2
uniprot id: A0A8B8SFF6
names: Similarity
messages: Belongs to the FXYD family.

419612:RPS10
gene id: 419612:RPS10
uniprot id: A0A8B6YBM8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

419612:LOC102504326
gene id: 419612:LOC102504326
uniprot id: A0A8B6YE09
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CEP20
gene id: 419612:CEP20
uniprot id: A0A8B6YAF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: centriole
messages: cilium basal body

419612:AK8
gene id: 419612:AK8
uniprot id: A0A8B8SX38
uniprot id: A0A8B8SX43
uniprot id: A0A8B8SX94
uniprot id: A0A8B8SX99
uniprot id: A0A8B8SXH5
uniprot id: A0A8B8SXI0
uniprot id: A0A8B8SXR5
uniprot id: A0A8B8SXS0
uniprot id: A0A8B8SYB3
uniprot id: A0A8B8SYB7
names: Similarity
messages: Belongs to the adenylate kinase family.

419612:IQSEC1
gene id: 419612:IQSEC1
uniprot id: A0A8B8R9M0
names: Similarity
messages: Belongs to the BRAG family.

419612:LOC102507673
gene id: 419612:LOC102507673
uniprot id: A0A8B8U529
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

419612:BICD2
gene id: 419612:BICD2
uniprot id: A0A8B8SUT1
names: Similarity
messages: Belongs to the BicD family.

419612:LOC102520090
gene id: 419612:LOC102520090
uniprot id: A0A8B8SFM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

419612:MAF1
gene id: 419612:MAF1
uniprot id: A0A8B8S0M2
uniprot id: A0A8B8S283
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

419612:TMEM251
gene id: 419612:TMEM251
uniprot id: A0A8B6YF63
uniprot id: A0A8B8T8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LYSET family.
messages: Membrane

419612:ARAP1
gene id: 419612:ARAP1
uniprot id: A0A8B8TSD4
uniprot id: A0A8B8TSE2
uniprot id: A0A8B8TSE5
uniprot id: A0A8B8TTA3
uniprot id: A0A8B8TTG6
names: Subcellular Location Annotation
messages: Cytoplasm

419612:CSRNP2
gene id: 419612:CSRNP2
uniprot id: S9XIY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

419612:ALAS1
gene id: 419612:ALAS1
uniprot id: A0A8B6YCH3
uniprot id: A0A8B7K6T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

419612:TNK1
gene id: 419612:TNK1
uniprot id: A0A8B8UJ23
uniprot id: A0A8B8UJH6
names: Subcellular Location Annotation
messages: Cell membrane

419612:LOC102503748
gene id: 419612:LOC102503748
uniprot id: A0A8B7KGP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CDC42BPB
gene id: 419612:CDC42BPB
uniprot id: A0A8B8T8P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

419612:SMC4
gene id: 419612:SMC4
uniprot id: A0A8B8TFW3
uniprot id: A0A8B8TH84
uniprot id: A0A8B8THA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Chromosome
messages: Nucleus

419612:LAMTOR2
gene id: 419612:LAMTOR2
uniprot id: S9XLY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

419612:SEMA6A
gene id: 419612:SEMA6A
uniprot id: A0A8B8SQJ9
uniprot id: A0A8B8SRB7
uniprot id: A0A8B8SRQ6
uniprot id: A0A8B8SSI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:GUCY2F
gene id: 419612:GUCY2F
uniprot id: A0A8B8SK73
uniprot id: A0A8B8SK78
uniprot id: A0A8B8SLB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

419612:HEBP1
gene id: 419612:HEBP1
uniprot id: A0A8B8SG96
names: Similarity
messages: Belongs to the HEBP family.

419612:RPS5
gene id: 419612:RPS5
uniprot id: A0A8B7KEC8
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

419612:HSD17B8
gene id: 419612:HSD17B8
uniprot id: A0A8B8RL73
uniprot id: A0A8B8RNE3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:TRMO
gene id: 419612:TRMO
uniprot id: A0A8B7KE05
uniprot id: A0A8B8SVE0
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

419612:LOC102524060
gene id: 419612:LOC102524060
uniprot id: A0A8B7K4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SH3BGRL3
gene id: 419612:SH3BGRL3
uniprot id: A0A8B8UBE8
names: Similarity
messages: Belongs to the SH3BGR family.

419612:LOC102518919
gene id: 419612:LOC102518919
uniprot id: A0A8B7K8A0
uniprot id: A0A8B8RNA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:LOC102503642
gene id: 419612:LOC102503642
uniprot id: A0A8B6YN03
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SLBP
gene id: 419612:SLBP
uniprot id: A0A8B8U1H9
names: Similarity
messages: Belongs to the SLBP family.

419612:B3GAT3
gene id: 419612:B3GAT3
uniprot id: A0A8B8TUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:LOC102519724
gene id: 419612:LOC102519724
uniprot id: A0A8B6YFR4
uniprot id: A0A8B7K9Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

419612:CPOX
gene id: 419612:CPOX
uniprot id: A0A8B8TVH7
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

419612:GTF2A1
gene id: 419612:GTF2A1
uniprot id: A0A8B8T8W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

419612:PGF
gene id: 419612:PGF
uniprot id: A0A8B6YF52
uniprot id: A0A8B6YFH0
uniprot id: A0A8B7K9S7
uniprot id: A0A8B8T7P3
uniprot id: A0A8B8T7V9
uniprot id: A0A8B8T888
uniprot id: A0A8B8T8L4
uniprot id: A0A8B8T8M0
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

419612:ATP5F1B
gene id: 419612:ATP5F1B
uniprot id: A0A8B6YBG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

419612:CDC25A
gene id: 419612:CDC25A
uniprot id: A0A8B8R925
uniprot id: A0A8B8R932
uniprot id: A0A8B8R971
uniprot id: A0A8B8RB79
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

419612:CDK10
gene id: 419612:CDK10
uniprot id: A0A8B6Y640
uniprot id: A0A8B8RRJ1
uniprot id: A0A8B8RRJ2
uniprot id: A0A8B8RRJ6
uniprot id: A0A8B8RRJ7
uniprot id: A0A8B8RS81
uniprot id: A0A8B8RTI8
uniprot id: A0A8B8RTJ3
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:DCTN4
gene id: 419612:DCTN4
uniprot id: A0A8B6Y821
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunit 4 family.
messages: cell cortex
messages: centrosome
messages: sarcomere
messages: stress fiber

419612:IQCG
gene id: 419612:IQCG
uniprot id: A0A8B7K777
uniprot id: A0A8B8T3X4
uniprot id: A0A8B8T4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC9 family.
messages: flagellum
messages: flagellum axoneme

419612:PSPH
gene id: 419612:PSPH
uniprot id: A0A8B8RE56
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

419612:LOC102517732
gene id: 419612:LOC102517732
uniprot id: A0A8B6YNN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PIWIL1
gene id: 419612:PIWIL1
uniprot id: A0A8B8SC07
uniprot id: A0A8B8SC16
uniprot id: A0A8B8SD63
uniprot id: A0A8B8SDC5
uniprot id: A0A8B8SEI9
names: Similarity
messages: Belongs to the argonaute family.

419612:LOC102518832
gene id: 419612:LOC102518832
uniprot id: A0A8B6YBQ8
uniprot id: A0A8B8TJT7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

419612:NIPSNAP1
gene id: 419612:NIPSNAP1
uniprot id: A0A8B8SE63
names: Similarity
messages: Belongs to the NipSnap family.

419612:MAN1C1
gene id: 419612:MAN1C1
uniprot id: A0A8B7KDC0
uniprot id: A0A8B8UAR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

419612:NUP210L
gene id: 419612:NUP210L
uniprot id: A0A8B6Y8R4
names: Similarity
messages: Belongs to the NUP210 family.

419612:SGCD
gene id: 419612:SGCD
uniprot id: A0A8B7K4A2
uniprot id: A0A8B8SSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

419612:LOC102519520
gene id: 419612:LOC102519520
uniprot id: A0A8B6Y8N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TCP11
gene id: 419612:TCP11
uniprot id: A0A8B6YFL4
uniprot id: A0A8B8RNN3
names: Similarity
messages: Belongs to the TCP11 family.

419612:RBM46
gene id: 419612:RBM46
uniprot id: A0A8B7KDY7
uniprot id: A0A8B8RTJ2
uniprot id: A0A8B8RTJ5
uniprot id: A0A8B8RTL6
uniprot id: A0A8B8RTM2
names: Subcellular Location Annotation
messages: Cytoplasm

419612:AQP11
gene id: 419612:AQP11
uniprot id: A0A8B6YLU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Cell membrane
messages: Membrane

419612:LOC102516808
gene id: 419612:LOC102516808
uniprot id: S9XN39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102516472
gene id: 419612:LOC102516472
uniprot id: S9XQ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SMC5
gene id: 419612:SMC5
uniprot id: A0A8B8SUB8
uniprot id: A0A8B8SUJ4
uniprot id: A0A8B8SUR3
uniprot id: A0A8B8SV58
uniprot id: A0A8B8SVV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

419612:TADA2B
gene id: 419612:TADA2B
uniprot id: A0A8B8U589
names: Subcellular Location Annotation
messages: Nucleus

419612:XIRP2
gene id: 419612:XIRP2
uniprot id: A0A8B6YBQ9
uniprot id: A0A8B8T088
names: Domain
names: Function
names: Similarity
messages: Belongs to the Xin family.
messages: Protects actin filaments from depolymerization.
messages: Xin repeats bind F-actin.

419612:KIF17
gene id: 419612:KIF17
uniprot id: A0A8B7KCC2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:LOC116662712
gene id: 419612:LOC116662712
uniprot id: A0A8B8SSD6
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:GHRL
gene id: 419612:GHRL
uniprot id: A0A8B6Y5U6
uniprot id: A0A8B7K825
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
messages: O-octanoylation is essential for ghrelin activity.
messages: Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
messages: Secreted

419612:FOXO1
gene id: 419612:FOXO1
uniprot id: A0A8B8UCS6
uniprot id: A0A8B8UCW0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

419612:DDIT3
gene id: 419612:DDIT3
uniprot id: S9Y6D0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Cytoplasm
messages: Heterodimer.
messages: Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response.
messages: Nucleus
messages: Phosphorylation at serine residues by MAPK14 enhances its transcriptional activation activity while phosphorylation at serine residues by CK2 inhibits its transcriptional activation activity.
messages: Ubiquitinated, leading to its degradation by the proteasome.

419612:CFAP91
gene id: 419612:CFAP91
uniprot id: A0A8B8T138
names: Similarity
messages: Belongs to the CFAP91 family.

419612:SLC30A4
gene id: 419612:SLC30A4
uniprot id: A0A8B8T4G4
uniprot id: A0A8B8T4H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

419612:CAMLG
gene id: 419612:CAMLG
uniprot id: A0A8B6YAW1
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

419612:ITGA2
gene id: 419612:ITGA2
uniprot id: A0A8B6YGF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

419612:YWHAZ
gene id: 419612:YWHAZ
uniprot id: A0A8B8S2U1
names: Similarity
messages: Belongs to the 14-3-3 family.

419612:RAB21
gene id: 419612:RAB21
uniprot id: A0A8B8U5R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: trans-Golgi network

419612:B4GALNT4
gene id: 419612:B4GALNT4
uniprot id: A0A8B8TVF7
uniprot id: A0A8B8TVG0
uniprot id: A0A8B8TWR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

419612:OTX2
gene id: 419612:OTX2
uniprot id: A0A8B6YBU7
uniprot id: A0A8B6YD63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

419612:BEX3
gene id: 419612:BEX3
uniprot id: A0A8B8SP74
uniprot id: A0A8B8SQ29
names: Similarity
messages: Belongs to the BEX family.

419612:RC3H2
gene id: 419612:RC3H2
uniprot id: A0A8B8SW10
uniprot id: A0A8B8SXC6
names: Subcellular Location Annotation
messages: P-body

419612:CKMT2
gene id: 419612:CKMT2
uniprot id: A0A8B8SLY4
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

419612:LOC102512250
gene id: 419612:LOC102512250
uniprot id: A0A8B6YQX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RPN1
gene id: 419612:RPN1
uniprot id: A0A8B8R9P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

419612:ADORA2B
gene id: 419612:ADORA2B
uniprot id: A0A8B8UHV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

419612:ORAI3
gene id: 419612:ORAI3
uniprot id: A0A8B8RGT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

419612:ICOS
gene id: 419612:ICOS
uniprot id: A0A8B6YSB2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

419612:TEKT2
gene id: 419612:TEKT2
uniprot id: A0A8B7KAY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

419612:ERAL1
gene id: 419612:ERAL1
uniprot id: A0A8B8R670
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.

419612:SCPEP1
gene id: 419612:SCPEP1
uniprot id: A0A8B6YCD6
names: Similarity
messages: Belongs to the peptidase S10 family.

419612:VPS51
gene id: 419612:VPS51
uniprot id: A0A8B8TTP2
uniprot id: A0A8B8TUS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

419612:G6PC2
gene id: 419612:G6PC2
uniprot id: A0A8B6YDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

419612:MRPL4
gene id: 419612:MRPL4
uniprot id: A0A8B8RVQ9
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

419612:GALNT13
gene id: 419612:GALNT13
uniprot id: A0A8B8T094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

419612:LOC102514676
gene id: 419612:LOC102514676
uniprot id: A0A8B6YLD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RPLP2
gene id: 419612:RPLP2
uniprot id: A0A8B8TWH2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

419612:GTPBP3
gene id: 419612:GTPBP3
uniprot id: A0A8B7K3B8
uniprot id: A0A8B8RTD1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

419612:ARL8A
gene id: 419612:ARL8A
uniprot id: A0A8B8RZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: spindle

419612:B3GNT3
gene id: 419612:B3GNT3
uniprot id: A0A8B7K5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:LOC102513941
gene id: 419612:LOC102513941
uniprot id: A0A8B7KH01
uniprot id: A0A8B8TCJ4
uniprot id: A0A8B8TCJ5
uniprot id: A0A8B8TCL5
uniprot id: A0A8B8TDS9
names: Subcellular Location Annotation
messages: Membrane

419612:TPP2
gene id: 419612:TPP2
uniprot id: A0A8B8UDD2
uniprot id: A0A8B8UDD4
uniprot id: A0A8B8UDD7
uniprot id: A0A8B8UE40
uniprot id: A0A8B8UEQ5
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:CNOT1
gene id: 419612:CNOT1
uniprot id: A0A8B6YPE9
uniprot id: A0A8B6YRF1
uniprot id: A0A8B7KFI4
uniprot id: A0A8B7KHF6
uniprot id: A0A8B8TJB3
uniprot id: A0A8B8TJC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

419612:LOC102513120
gene id: 419612:LOC102513120
uniprot id: A0A8B7KDE9
names: Similarity
messages: Belongs to the DPH3 family.

419612:ADGRG7
gene id: 419612:ADGRG7
uniprot id: A0A8B6YMP7
uniprot id: A0A8B7KCG8
uniprot id: A0A8B8SVT7
names: Subcellular Location Annotation
messages: Membrane

419612:SCAMP1
gene id: 419612:SCAMP1
uniprot id: A0A8B8SLE7
uniprot id: A0A8B8SLP8
uniprot id: A0A8B8SMK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

419612:BPIFC
gene id: 419612:BPIFC
uniprot id: A0A8B8U521
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

419612:PRKAR2B
gene id: 419612:PRKAR2B
uniprot id: A0A8B8TCZ0
uniprot id: A0A8B8TD07
uniprot id: A0A8B8TE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

419612:DDX4
gene id: 419612:DDX4
uniprot id: A0A8B8SEL1
uniprot id: A0A8B8SEP7
uniprot id: A0A8B8SFY4
names: Similarity
messages: Belongs to the DEAD box helicase family.

419612:LOC116666878
gene id: 419612:LOC116666878
uniprot id: A0A8B8TVW0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:CASC1
gene id: 419612:CASC1
uniprot id: A0A8B8SGJ3
uniprot id: A0A8B8SGJ4
uniprot id: A0A8B8SGJ9
uniprot id: A0A8B8SHN2
uniprot id: A0A8B8SHN6
uniprot id: A0A8B8SHS4
uniprot id: A0A8B8SJ40
names: Similarity
messages: Belongs to the DNAI7 family.

419612:VIPR2
gene id: 419612:VIPR2
uniprot id: A0A8B8T9C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

419612:LOC116665703
gene id: 419612:LOC116665703
uniprot id: A0A8B8TIB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

419612:PLK2
gene id: 419612:PLK2
uniprot id: A0A8B8SF73
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

419612:TOMM40L
gene id: 419612:TOMM40L
uniprot id: A0A8B6Y5R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

419612:NDUFC1
gene id: 419612:NDUFC1
uniprot id: A0A8B6YR04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

419612:CCL14
gene id: 419612:CCL14
uniprot id: A0A8B6Y7F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

419612:HADHB
gene id: 419612:HADHB
uniprot id: A0A8B8UFJ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

419612:CAMTA1
gene id: 419612:CAMTA1
uniprot id: A0A8B8U8S4
uniprot id: A0A8B8U9L4
uniprot id: A0A8B8U9Q3
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

419612:STRA6
gene id: 419612:STRA6
uniprot id: A0A8B8S4Z3
uniprot id: A0A8B8S579
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:HLF
gene id: 419612:HLF
uniprot id: A0A8B6Y9B6
uniprot id: A0A8B8UIY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

419612:CLIC4
gene id: 419612:CLIC4
uniprot id: A0A8B8UB83
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

419612:LOC102514204
gene id: 419612:LOC102514204
uniprot id: A0A8B8SLZ4
uniprot id: A0A8B8SLZ6
uniprot id: A0A8B8SM00
uniprot id: A0A8B8SN19
uniprot id: A0A8B8SP54
names: Similarity
messages: Belongs to the taxilin family.

419612:LOC116667981
gene id: 419612:LOC116667981
uniprot id: A0A8B8U783
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

419612:AKAP12
gene id: 419612:AKAP12
uniprot id: A0A8B7KBA2
uniprot id: A0A8B8TFT3
names: Subcellular Location Annotation
messages: Membrane

419612:BDNF
gene id: 419612:BDNF
uniprot id: A0A8B6YPH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NGF-beta family.
messages: During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
messages: Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
messages: Monomers and homodimers (By similarity). Binds to NTRK2/TRKB. Can form heterodimers with other neurotrophin family members, such as NTF3 and NTF4 (in vitro), but the physiological relevance of this is not clear (By similarity). BDNF precursor form: interacts with the heterodimer formed by NGFR and SORCS2. Mature BDNF has much lower affinity for the heterodimer formed by NGFR and SORCS2.
messages: Monomers and homodimers. Binds to NTRK2/TRKB.
messages: Secreted

419612:CNIH2
gene id: 419612:CNIH2
uniprot id: A0A8B8TV88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

419612:EXOC3L4
gene id: 419612:EXOC3L4
uniprot id: A0A8B8T8U7
names: Similarity
messages: Belongs to the SEC6 family.

419612:LOC116667828
gene id: 419612:LOC116667828
uniprot id: A0A8B8U673
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102513226
gene id: 419612:LOC102513226
uniprot id: A0A8B6Y971
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102518898
gene id: 419612:LOC102518898
uniprot id: S9YCK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TCL1B
gene id: 419612:TCL1B
uniprot id: A0A8B7K9E8
names: Similarity
messages: Belongs to the TCL1 family.

419612:LYPLA2
gene id: 419612:LYPLA2
uniprot id: A0A8B6YEB7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

419612:EPHB4
gene id: 419612:EPHB4
uniprot id: A0A8B6YMB2
uniprot id: A0A8B7KEU1
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102504992
gene id: 419612:LOC102504992
uniprot id: S9XC23
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RAG1
gene id: 419612:RAG1
uniprot id: A0A8B6YPG6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

419612:CMC4
gene id: 419612:CMC4
uniprot id: A0A8B8SMQ0
names: Similarity
messages: Belongs to the CMC4 family.

419612:DEFB116
gene id: 419612:DEFB116
uniprot id: A0A8B7KGB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

419612:LOC102504108
gene id: 419612:LOC102504108
uniprot id: A0A8B6YIA0
uniprot id: A0A8B7KBZ0
uniprot id: A0A8B7KBZ6
uniprot id: A0A8B7KCA0
uniprot id: A0A8B7KD01
uniprot id: A0A8B7KE24
uniprot id: A0A8B8SUN4
uniprot id: A0A8B8SUW8
uniprot id: A0A8B8SV16
uniprot id: A0A8B8SV24
uniprot id: A0A8B8SVG7
uniprot id: A0A8B8SW65
names: Subcellular Location Annotation
messages: Cytoplasm

419612:LOC102524157
gene id: 419612:LOC102524157
uniprot id: S9XPH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:LOC102513878
gene id: 419612:LOC102513878
uniprot id: A0A8B8RBK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

419612:UPF2
gene id: 419612:UPF2
uniprot id: A0A8B8SJ90
names: Subcellular Location Annotation
messages: Cytoplasm

419612:MINDY2
gene id: 419612:MINDY2
uniprot id: A0A8B8T3Y7
uniprot id: A0A8B8T3Y8
uniprot id: A0A8B8T4Q9
uniprot id: A0A8B8T4S1
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

419612:LOC102513259
gene id: 419612:LOC102513259
uniprot id: A0A8B8S5W9
names: Similarity
messages: Belongs to the SNF7 family.

419612:KHSRP
gene id: 419612:KHSRP
uniprot id: A0A8B8RUL9
uniprot id: A0A8B8RVR2
names: Subcellular Location Annotation
messages: Nucleus

419612:ATF7IP
gene id: 419612:ATF7IP
uniprot id: A0A8B6YQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

419612:SFTPD
gene id: 419612:SFTPD
uniprot id: A0A8B6YF82
names: Similarity
names: Subunit
messages: Belongs to the SFTPD family.
messages: Oligomeric complex of 4 set of homotrimers.

419612:GPRC6A
gene id: 419612:GPRC6A
uniprot id: A0A8B6YRG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:KIFC3
gene id: 419612:KIFC3
uniprot id: A0A8B8TJ89
uniprot id: A0A8B8TJ92
uniprot id: A0A8B8TJA2
uniprot id: A0A8B8TJF9
uniprot id: A0A8B8TJG5
uniprot id: A0A8B8TKH1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:CMTM5
gene id: 419612:CMTM5
uniprot id: A0A8B6Y822
uniprot id: A0A8B8T5R8
uniprot id: A0A8B8T628
names: Subcellular Location Annotation
messages: Membrane

419612:NCOA1
gene id: 419612:NCOA1
uniprot id: A0A8B8UFB8
uniprot id: A0A8B8UFE3
uniprot id: A0A8B8UG08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

419612:GNL2
gene id: 419612:GNL2
uniprot id: A0A8B8UC23
uniprot id: A0A8B8UC69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

419612:GJB7
gene id: 419612:GJB7
uniprot id: S9YNH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

419612:ASF1B
gene id: 419612:ASF1B
uniprot id: S9XAR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

419612:LIN9
gene id: 419612:LIN9
uniprot id: A0A8B8RX01
uniprot id: A0A8B8RYB7
names: Similarity
messages: Belongs to the lin-9 family.

419612:RPL19
gene id: 419612:RPL19
uniprot id: A0A8B8R729
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

419612:YY1
gene id: 419612:YY1
uniprot id: A0A8B8T9F2
names: Similarity
messages: Belongs to the YY transcription factor family.

419612:TARS2
gene id: 419612:TARS2
uniprot id: A0A8B6YHH1
uniprot id: A0A8B7KB50
uniprot id: A0A8B8RSC4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

419612:ORAI2
gene id: 419612:ORAI2
uniprot id: A0A8B6YG10
uniprot id: A0A8B8RC06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

419612:RAD23B
gene id: 419612:RAD23B
uniprot id: A0A8B8SVB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

419612:PPOX
gene id: 419612:PPOX
uniprot id: A0A8B7KCE2
uniprot id: A0A8B7KCQ1
uniprot id: A0A8B8RPA7
uniprot id: A0A8B8RR11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

419612:ROM1
gene id: 419612:ROM1
uniprot id: A0A8B8TT83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

419612:MALSU1
gene id: 419612:MALSU1
uniprot id: A0A8B8TBX3
uniprot id: A0A8B8TD53
names: Similarity
messages: Belongs to the Iojap/RsfS family.

419612:LOC116663644
gene id: 419612:LOC116663644
uniprot id: A0A8B8T0N8
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

419612:RGS3
gene id: 419612:RGS3
uniprot id: A0A8B8SVK1
names: Subcellular Location Annotation
messages: Cytoplasm

419612:VWDE
gene id: 419612:VWDE
uniprot id: A0A8B8TC88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:NAA10
gene id: 419612:NAA10
uniprot id: A0A8B8SMC6
uniprot id: A0A8B8SNE4
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

419612:NUF2
gene id: 419612:NUF2
uniprot id: A0A8B8RPM5
names: Similarity
messages: Belongs to the NUF2 family.

419612:TMEM200A
gene id: 419612:TMEM200A
uniprot id: A0A8B6YBS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

419612:B3GALNT2
gene id: 419612:B3GALNT2
uniprot id: A0A8B8TZM8
uniprot id: A0A8B8TZN0
uniprot id: A0A8B8TZN3
uniprot id: A0A8B8TZN5
uniprot id: A0A8B8TZV0
uniprot id: A0A8B8U0N8
uniprot id: A0A8B8U0Y1
uniprot id: A0A8B8U0Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Membrane

419612:SCRIB
gene id: 419612:SCRIB
uniprot id: A0A8B8RZS9
uniprot id: A0A8B8RZT4
uniprot id: A0A8B8RZU2
uniprot id: A0A8B8RZU3
uniprot id: A0A8B8RZU7
uniprot id: A0A8B8S152
uniprot id: A0A8B8S157
uniprot id: A0A8B8S166
uniprot id: A0A8B8S1D2
uniprot id: A0A8B8S1D8
uniprot id: A0A8B8S1E8
uniprot id: A0A8B8S1G4
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

419612:LOC102510072
gene id: 419612:LOC102510072
uniprot id: A0A8B6YJZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

419612:LOC102520230
gene id: 419612:LOC102520230
uniprot id: A0A8B8S8M4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:CDS2
gene id: 419612:CDS2
uniprot id: A0A8B8RII3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

419612:CWC25
gene id: 419612:CWC25
uniprot id: A0A8B6Y7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

419612:GRM6
gene id: 419612:GRM6
uniprot id: A0A8B8RWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

419612:GNGT2
gene id: 419612:GNGT2
uniprot id: A0A8B7KH59
uniprot id: S9WBK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

419612:IFNGR2
gene id: 419612:IFNGR2
uniprot id: A0A8B8SIH4
uniprot id: A0A8B8SJY0
names: Subcellular Location Annotation
messages: Membrane

419612:PDE1B
gene id: 419612:PDE1B
uniprot id: A0A8B6YD98
uniprot id: A0A8B8U2W8
uniprot id: A0A8B8U3W4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

419612:LOC102523499
gene id: 419612:LOC102523499
uniprot id: S9Y4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC116667351
gene id: 419612:LOC116667351
uniprot id: A0A8B8U169
names: Subcellular Location Annotation
messages: Nucleus

419612:CSF1R
gene id: 419612:CSF1R
uniprot id: A0A8B8ST81
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.

419612:KRT5
gene id: 419612:KRT5
uniprot id: A0A8B6YDD0
names: Similarity
messages: Belongs to the intermediate filament family.

419612:ATP6V0A2
gene id: 419612:ATP6V0A2
uniprot id: A0A8B8SAC7
uniprot id: A0A8B8SBJ9
uniprot id: A0A8B8SBP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

419612:SLC37A4
gene id: 419612:SLC37A4
uniprot id: A0A8B8SEA6
uniprot id: S9XK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

419612:TASOR2
gene id: 419612:TASOR2
uniprot id: A0A8B8SHL0
uniprot id: A0A8B8SIN9
uniprot id: A0A8B8SIU7
names: Similarity
messages: Belongs to the TASOR family.

419612:TPRG1
gene id: 419612:TPRG1
uniprot id: A0A8B6YN05
names: Similarity
messages: Belongs to the TPRG1 family.

419612:B3GLCT
gene id: 419612:B3GLCT
uniprot id: A0A8B8UD47
names: Subcellular Location Annotation
messages: Membrane

419612:TLN1
gene id: 419612:TLN1
uniprot id: A0A8B8SUZ6
names: Subcellular Location Annotation
messages: cytoskeleton

419612:CDKL1
gene id: 419612:CDKL1
uniprot id: A0A8B8T6T8
uniprot id: A0A8B8T760
uniprot id: A0A8B8T7E9
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:LOC102516245
gene id: 419612:LOC102516245
uniprot id: A0A8B7KGY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

419612:CENPBD1
gene id: 419612:CENPBD1
uniprot id: A0A8B6Y6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

419612:CENPN
gene id: 419612:CENPN
uniprot id: A0A8B7K9Q2
uniprot id: A0A8B8TKF1
uniprot id: A0A8B8TKR3
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

419612:TAF1A
gene id: 419612:TAF1A
uniprot id: A0A8B7KC86
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1B. Interaction of the SL1/TIF-IB subunits with TBP excludes interaction of TBP with the transcription factor IID (TFIID) subunits.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

419612:LOC106730027
gene id: 419612:LOC106730027
uniprot id: A0A8B8S9C9
uniprot id: A0A8B8SAK4
uniprot id: A0A8B8SBP0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:DIPK1C
gene id: 419612:DIPK1C
uniprot id: A0A8B8S840
uniprot id: A0A8B8S841
uniprot id: A0A8B8S9D3
uniprot id: A0A8B8S9I9
uniprot id: A0A8B8SAB3
names: Similarity
messages: Belongs to the DIPK family.

419612:LOC116662238
gene id: 419612:LOC116662238
uniprot id: A0A8B8SNU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

419612:LOC102505423
gene id: 419612:LOC102505423
uniprot id: A0A8B6YRP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102508196
gene id: 419612:LOC102508196
uniprot id: S9WVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

419612:LOC102522982
gene id: 419612:LOC102522982
uniprot id: A0A8B8RIB1
names: Subcellular Location Annotation
messages: Nucleus

419612:PTPN21
gene id: 419612:PTPN21
uniprot id: A0A8B8T8X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

419612:SLC13A5
gene id: 419612:SLC13A5
uniprot id: A0A8B6Y8Z2
uniprot id: A0A8B7K726
uniprot id: A0A8B8UHN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

419612:WNT2
gene id: 419612:WNT2
uniprot id: A0A8B8TBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

419612:LOC116666676
gene id: 419612:LOC116666676
uniprot id: A0A8B8TVR3
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:RPA3
gene id: 419612:RPA3
uniprot id: A0A8B6YER3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

419612:SERPINB13
gene id: 419612:SERPINB13
uniprot id: A0A8B6YE05
uniprot id: A0A8B8SAA0
names: Similarity
messages: Belongs to the serpin family.

419612:SLC27A2
gene id: 419612:SLC27A2
uniprot id: A0A8B6YGB9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

419612:LOC102507203
gene id: 419612:LOC102507203
uniprot id: S9XDQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102516333
gene id: 419612:LOC102516333
uniprot id: A0A8B7KFF8
names: Similarity
messages: Belongs to the actin family.

419612:MEIS1
gene id: 419612:MEIS1
uniprot id: A0A8B6YPD0
uniprot id: A0A8B7KHN7
uniprot id: A0A8B8UG87
uniprot id: A0A8B8UHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

419612:MEF2A
gene id: 419612:MEF2A
uniprot id: A0A8B8S3W3
uniprot id: A0A8B8S3X0
uniprot id: A0A8B8S3X5
uniprot id: A0A8B8S577
uniprot id: A0A8B8S5F6
uniprot id: A0A8B8S5T8
uniprot id: A0A8B8S5U4
names: Subcellular Location Annotation
messages: Nucleus

419612:CLIC5
gene id: 419612:CLIC5
uniprot id: A0A8B6YKR9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

419612:KCNH4
gene id: 419612:KCNH4
uniprot id: A0A8B6YE72
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

419612:EIF4EBP1
gene id: 419612:EIF4EBP1
uniprot id: A0A8B8S259
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

419612:RPF1
gene id: 419612:RPF1
uniprot id: A0A8B6YK82
names: Subcellular Location Annotation
messages: nucleolus

419612:ADAMDEC1
gene id: 419612:ADAMDEC1
uniprot id: A0A8B6YNR4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:CXCR3
gene id: 419612:CXCR3
uniprot id: A0A8B7KD96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

419612:KIF5B
gene id: 419612:KIF5B
uniprot id: A0A8B8SI29
uniprot id: A0A8B8SI32
uniprot id: A0A8B8SJ71
uniprot id: A0A8B8SKJ9
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MNX1
gene id: 419612:MNX1
uniprot id: A0A8B8T9V6
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102522524
gene id: 419612:LOC102522524
uniprot id: A0A8B8UHR0
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

419612:FAM118A
gene id: 419612:FAM118A
uniprot id: A0A8B8U161
uniprot id: A0A8B8U2F8
uniprot id: A0A8B8U2G2
names: Similarity
messages: Belongs to the FAM118 family.

419612:ARF4
gene id: 419612:ARF4
uniprot id: A0A8B8R822
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

419612:KCNH1
gene id: 419612:KCNH1
uniprot id: A0A8B8RWG2
names: Subcellular Location Annotation
messages: Membrane

419612:PIK3IP1
gene id: 419612:PIK3IP1
uniprot id: A0A8B8SCD9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MC5R
gene id: 419612:MC5R
uniprot id: A0A8B8RZU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

419612:S100A8
gene id: 419612:S100A8
uniprot id: S9XE92
names: Similarity
messages: Belongs to the S-100 family.

419612:SLC35A4
gene id: 419612:SLC35A4
uniprot id: S9Z146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

419612:LAMP3
gene id: 419612:LAMP3
uniprot id: A0A8B8TB52
uniprot id: A0A8B8TBI5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

419612:ST14
gene id: 419612:ST14
uniprot id: A0A8B8SEK2
uniprot id: A0A8B8SFS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S1 family.
messages: Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
messages: Interacts with CDCP1. May interact with TMEFF1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:ABCB5
gene id: 419612:ABCB5
uniprot id: A0A8B6YCW3
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102513561
gene id: 419612:LOC102513561
uniprot id: A0A8B8SK22
names: Similarity
messages: Belongs to the tubulin family.

419612:C34H12orf57
gene id: 419612:C34H12orf57
uniprot id: S9XP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

419612:SIGMAR1
gene id: 419612:SIGMAR1
uniprot id: A0A8B8STN4
uniprot id: A0A8B8SUG5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cell junction
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Lipid droplet
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: Postsynaptic density membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle
messages: growth cone

419612:SLC25A16
gene id: 419612:SLC25A16
uniprot id: A0A8B8TYM4
uniprot id: A0A8B8TZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:ADORA3
gene id: 419612:ADORA3
uniprot id: A0A8B7KAV6
uniprot id: A0A8B8TLT6
uniprot id: A0A8B8TLU8
uniprot id: T0MFV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

419612:GALNT9
gene id: 419612:GALNT9
uniprot id: A0A8B8SB03
uniprot id: A0A8B8SC65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

419612:EXO5
gene id: 419612:EXO5
uniprot id: A0A8B8U6B4
names: Similarity
messages: Belongs to the EXO5 family.

419612:RNF40
gene id: 419612:RNF40
uniprot id: A0A8B8REB6
uniprot id: T0MFC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

419612:PI4K2B
gene id: 419612:PI4K2B
uniprot id: A0A8B8U8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

419612:NDUFB2
gene id: 419612:NDUFB2
uniprot id: A0A8B6YG98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

419612:CDH9
gene id: 419612:CDH9
uniprot id: A0A8B7K8J1
uniprot id: A0A8B8S820
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

419612:LOC106728467
gene id: 419612:LOC106728467
uniprot id: A0A8B7K386
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

419612:LOC102508612
gene id: 419612:LOC102508612
uniprot id: A0A8B8RFQ2
uniprot id: A0A8B8RI56
names: Subcellular Location Annotation
messages: Membrane

419612:SEC22C
gene id: 419612:SEC22C
uniprot id: A0A8B7K870
uniprot id: A0A8B8RAL3
uniprot id: A0A8B8RCQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

419612:PSMD5
gene id: 419612:PSMD5
uniprot id: A0A8B8SW51
uniprot id: A0A8B8SWK5
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

419612:PPIL2
gene id: 419612:PPIL2
uniprot id: A0A8B8SCC9
uniprot id: A0A8B8SDI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

419612:SYNE3
gene id: 419612:SYNE3
uniprot id: A0A8B8T892
names: Similarity
messages: Belongs to the nesprin family.

419612:FBL
gene id: 419612:FBL
uniprot id: A0A8B8TI76
uniprot id: A0A8B8TJG0
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

419612:SEC11A
gene id: 419612:SEC11A
uniprot id: A0A8B6YMJ4
uniprot id: A0A8B7KFA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:TMEM175
gene id: 419612:TMEM175
uniprot id: A0A8B6YAH5
uniprot id: A0A8B7K5D6
uniprot id: A0A8B7K5P9
uniprot id: A0A8B8U064
uniprot id: A0A8B8U0F9
uniprot id: A0A8B8U179
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

419612:VBP1
gene id: 419612:VBP1
uniprot id: A0A8B8SNR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

419612:SMPDL3B
gene id: 419612:SMPDL3B
uniprot id: A0A8B6YQ38
uniprot id: A0A8B8UB30
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

419612:LOC102510196
gene id: 419612:LOC102510196
uniprot id: S9W8E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:EBPL
gene id: 419612:EBPL
uniprot id: A0A8B6YF49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:MUTYH
gene id: 419612:MUTYH
uniprot id: A0A8B6Y9M3
uniprot id: A0A8B8U621
uniprot id: A0A8B8U6X9
uniprot id: A0A8B8U6Y3
uniprot id: A0A8B8U6Y6
uniprot id: A0A8B8U756
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

419612:NOP2
gene id: 419612:NOP2
uniprot id: A0A8B6Y7X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

419612:LOC102515509
gene id: 419612:LOC102515509
uniprot id: A0A8B7KHX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:NAAA
gene id: 419612:NAAA
uniprot id: A0A8B6Y999
uniprot id: A0A8B8R6W6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acid ceramidase family.
messages: Heterodimer.
messages: Lysosome

419612:LOC102518548
gene id: 419612:LOC102518548
uniprot id: A0A8B8TVR6
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

419612:TCTN3
gene id: 419612:TCTN3
uniprot id: A0A8B6Y6N9
uniprot id: A0A8B7KEX0
uniprot id: A0A8B7KF58
uniprot id: A0A8B8TXT0
uniprot id: A0A8B8TYT1
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

419612:GINS4
gene id: 419612:GINS4
uniprot id: A0A8B7KCP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

419612:ATF2
gene id: 419612:ATF2
uniprot id: A0A8B7KIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

419612:NBR1
gene id: 419612:NBR1
uniprot id: A0A8B6Y6T4
uniprot id: A0A8B8R595
names: Subcellular Location Annotation
messages: Lysosome
messages: autophagosome

419612:LOC102515984
gene id: 419612:LOC102515984
uniprot id: A0A8B8SG57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

419612:F2
gene id: 419612:F2
uniprot id: A0A8B8TR08
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

419612:MEPCE
gene id: 419612:MEPCE
uniprot id: A0A8B8RCA0
names: Similarity
messages: Belongs to the methyltransferase superfamily.

419612:F3
gene id: 419612:F3
uniprot id: A0A8B8TL92
uniprot id: A0A8B8TMH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.
messages: Membrane

419612:DDX51
gene id: 419612:DDX51
uniprot id: A0A8B8SD30
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

419612:PHF10
gene id: 419612:PHF10
uniprot id: A0A8B8TGC4
uniprot id: A0A8B8TGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

419612:MDM2
gene id: 419612:MDM2
uniprot id: A0A8B7KD58
uniprot id: A0A8B8U3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

419612:ENAH
gene id: 419612:ENAH
uniprot id: A0A8B8RX21
uniprot id: A0A8B8RX22
uniprot id: A0A8B8RYD3
uniprot id: A0A8B8RYD7
uniprot id: A0A8B8RYG9
uniprot id: A0A8B8RYH3
uniprot id: A0A8B8RYS6
uniprot id: A0A8B8RYT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

419612:LOC102517717
gene id: 419612:LOC102517717
uniprot id: A0A8B6YIQ5
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:ELOVL5
gene id: 419612:ELOVL5
uniprot id: A0A8B8RML1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: dendrite

419612:SPI1
gene id: 419612:SPI1
uniprot id: A0A8B8TQH8
uniprot id: A0A8B8TR86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:C3H5orf63
gene id: 419612:C3H5orf63
uniprot id: A0A8B8SRJ9
names: Similarity
messages: Belongs to the glutaredoxin family.

419612:INS
gene id: 419612:INS
uniprot id: A0A8B8TW19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

419612:HDGFL2
gene id: 419612:HDGFL2
uniprot id: A0A8B8RUX3
uniprot id: A0A8B8RUX6
uniprot id: A0A8B8RW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

419612:GPR146
gene id: 419612:GPR146
uniprot id: S9XWN1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:TMEM233
gene id: 419612:TMEM233
uniprot id: A0A8B6YMG1
uniprot id: A0A8B8SBN2
uniprot id: A0A8B8SCU3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

419612:HENMT1
gene id: 419612:HENMT1
uniprot id: A0A8B6YF61
uniprot id: A0A8B8TLK8
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

419612:RYBP
gene id: 419612:RYBP
uniprot id: A0A8B8R9R3
names: Subcellular Location Annotation
messages: Nucleus

419612:L3MBTL3
gene id: 419612:L3MBTL3
uniprot id: A0A8B8TEY5
uniprot id: A0A8B8TEY6
names: Subcellular Location Annotation
messages: Nucleus

419612:ACADS
gene id: 419612:ACADS
uniprot id: A0A8B8SDJ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

419612:PDIA2
gene id: 419612:PDIA2
uniprot id: A0A8B6YCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

419612:FGF1
gene id: 419612:FGF1
uniprot id: A0A8B8SSM0
uniprot id: S9Y262
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

419612:MDGA1
gene id: 419612:MDGA1
uniprot id: A0A8B6Y652
uniprot id: A0A8B8RLR4
uniprot id: A0A8B8RM10
uniprot id: A0A8B8RNH8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:LOC102517898
gene id: 419612:LOC102517898
uniprot id: S9XL46
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102509501
gene id: 419612:LOC102509501
uniprot id: A0A8B8RUN1
names: Function
names: Similarity
messages: Belongs to the type-1 OGG1 family.
messages: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.

419612:ACYP2
gene id: 419612:ACYP2
uniprot id: A0A8B8UFT4
uniprot id: A0A8B8UGI4
uniprot id: A0A8B8UH78
names: Similarity
messages: Belongs to the acylphosphatase family.

419612:SELENOP
gene id: 419612:SELENOP
uniprot id: A0A8B6YND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein P family.
messages: Secreted

419612:SRPX
gene id: 419612:SRPX
uniprot id: A0A8B8SJ78
uniprot id: A0A8B8SKA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102520475
gene id: 419612:LOC102520475
uniprot id: A0A8B8TLW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

419612:ATP6V1A
gene id: 419612:ATP6V1A
uniprot id: A0A8B6YAB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Vesicle
messages: clathrin-coated vesicle membrane
messages: secretory vesicle

419612:LOC102507429
gene id: 419612:LOC102507429
uniprot id: A0A8B7KGP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:DOCK11
gene id: 419612:DOCK11
uniprot id: A0A8B8SNG3
uniprot id: A0A8B8SPQ4
uniprot id: A0A8B8SQM0
names: Similarity
messages: Belongs to the DOCK family.

419612:SLC35C1
gene id: 419612:SLC35C1
uniprot id: A0A8B6YFB9
uniprot id: A0A8B8TQX2
names: Subcellular Location Annotation
messages: Membrane

419612:DNAJC24
gene id: 419612:DNAJC24
uniprot id: A0A8B6YPI0
uniprot id: A0A8B7KHQ1
names: Similarity
messages: Belongs to the DPH4 family.

419612:DGAT2L6
gene id: 419612:DGAT2L6
uniprot id: A0A8B6YQ59
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SERPINA1
gene id: 419612:SERPINA1
uniprot id: A0A8B8T8Q7
names: Similarity
messages: Belongs to the serpin family.

419612:MRPL11
gene id: 419612:MRPL11
uniprot id: A0A8B8TU32
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

419612:SLC24A1
gene id: 419612:SLC24A1
uniprot id: A0A8B8T3F9
uniprot id: A0A8B8T3G2
uniprot id: A0A8B8T3T1
uniprot id: A0A8B8T481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

419612:GABRA1
gene id: 419612:GABRA1
uniprot id: A0A8B7KGB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:DGAT2
gene id: 419612:DGAT2
uniprot id: A0A8B6Y5U2
uniprot id: A0A8B8TSQ6
uniprot id: A0A8B8TTQ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102517605
gene id: 419612:LOC102517605
uniprot id: A0A8B8SJV3
uniprot id: A0A8B8SJV7
uniprot id: A0A8B8SJV8
uniprot id: A0A8B8SKZ2
uniprot id: A0A8B8SLA0
uniprot id: A0A8B8SLA3
uniprot id: A0A8B8SM83
uniprot id: A0A8B8SM88
names: Similarity
messages: Belongs to the FAM122 family.

419612:TMEM181
gene id: 419612:TMEM181
uniprot id: A0A8B8TFZ9
uniprot id: A0A8B8TG05
names: Subcellular Location Annotation
messages: Membrane

419612:NFIL3
gene id: 419612:NFIL3
uniprot id: A0A8B6Y908
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death.
messages: Belongs to the bZIP family. NFIL3 subfamily.
messages: Homodimer. Binds DNA as a dimer.
messages: Nucleus

419612:PHYHIPL
gene id: 419612:PHYHIPL
uniprot id: A0A8B8TYF7
uniprot id: A0A8B8TYI0
uniprot id: A0A8B8TZR7
names: Similarity
messages: Belongs to the PHYHIP family.

419612:CCNDBP1
gene id: 419612:CCNDBP1
uniprot id: A0A8B8T4T3
uniprot id: A0A8B8T5H8
names: Similarity
names: Subunit
messages: Belongs to the CCNDBP1 family.
messages: Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3.

419612:LOC102510950
gene id: 419612:LOC102510950
uniprot id: A0A8B7K7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

419612:AGBL5
gene id: 419612:AGBL5
uniprot id: A0A8B8UEU5
uniprot id: A0A8B8UFJ3
uniprot id: A0A8B8UFL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

419612:CXCR4
gene id: 419612:CXCR4
uniprot id: A0A8B6YPT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell junction
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

419612:PMP22
gene id: 419612:PMP22
uniprot id: A0A8B8UK20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

419612:SLC30A6
gene id: 419612:SLC30A6
uniprot id: A0A8B8UFV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

419612:MIS18A
gene id: 419612:MIS18A
uniprot id: A0A8B6YHY2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

419612:PEX16
gene id: 419612:PEX16
uniprot id: A0A8B6YF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

419612:PTGR2
gene id: 419612:PTGR2
uniprot id: A0A8B6YF66
uniprot id: A0A8B8T7T5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

419612:ZNF174
gene id: 419612:ZNF174
uniprot id: A0A8B8RGE2
uniprot id: A0A8B8RGM1
names: Subcellular Location Annotation
messages: Nucleus

419612:GABRR3
gene id: 419612:GABRR3
uniprot id: A0A8B8TU87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:SYNE1
gene id: 419612:SYNE1
uniprot id: A0A8B8TFR6
uniprot id: A0A8B8TFR9
uniprot id: A0A8B8TFS0
uniprot id: A0A8B8TFS3
uniprot id: A0A8B8TFS4
uniprot id: A0A8B8TFS7
uniprot id: A0A8B8TFT2
uniprot id: A0A8B8TFT6
uniprot id: A0A8B8TFT8
uniprot id: A0A8B8TFV1
uniprot id: A0A8B8TFV8
uniprot id: A0A8B8TH46
uniprot id: A0A8B8TH57
names: Similarity
messages: Belongs to the nesprin family.

419612:CENPU
gene id: 419612:CENPU
uniprot id: A0A8B7KCT7
uniprot id: A0A8B8S274
uniprot id: A0A8B8S3T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

419612:FZD8
gene id: 419612:FZD8
uniprot id: A0A8B8SH16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

419612:IL17A
gene id: 419612:IL17A
uniprot id: A0A8B6YQT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

419612:ARHGEF9
gene id: 419612:ARHGEF9
uniprot id: A0A8B8SP48
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.

419612:MARF1
gene id: 419612:MARF1
uniprot id: A0A8B6YAR6
uniprot id: A0A8B6YBN0
uniprot id: A0A8B6YE95
uniprot id: A0A8B8RFX5
uniprot id: A0A8B8RFY0
uniprot id: A0A8B8RFY8
uniprot id: A0A8B8RG44
uniprot id: A0A8B8RHV8
uniprot id: A0A8B8RIE1
names: Subcellular Location Annotation
messages: Peroxisome

419612:PARP6
gene id: 419612:PARP6
uniprot id: A0A8B8S488
uniprot id: A0A8B8S492
uniprot id: A0A8B8S4A2
uniprot id: A0A8B8S5J7
uniprot id: A0A8B8S678
names: Similarity
messages: Belongs to the ARTD/PARP family.

419612:EML6
gene id: 419612:EML6
uniprot id: A0A8B8UFS4
names: Function
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

419612:ACOX2
gene id: 419612:ACOX2
uniprot id: A0A8B7K9Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

419612:RCAN1
gene id: 419612:RCAN1
uniprot id: A0A8B6YHX7
uniprot id: A0A8B8S9E8
uniprot id: A0A8B8SB02
names: Similarity
messages: Belongs to the RCAN family.

419612:NR2C1
gene id: 419612:NR2C1
uniprot id: A0A8B8U4I6
uniprot id: A0A8B8U4J0
uniprot id: A0A8B8U5B0
uniprot id: A0A8B8U5B5
uniprot id: A0A8B8U5H8
uniprot id: A0A8B8U5P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

419612:CDKN1B
gene id: 419612:CDKN1B
uniprot id: A0A8B8SHR0
names: Similarity
messages: Belongs to the CDI family.

419612:LOC102518167
gene id: 419612:LOC102518167
uniprot id: S9WCB1
names: Similarity
messages: Belongs to the PRAME family.

419612:LOC106729365
gene id: 419612:LOC106729365
uniprot id: A0A8B8T3Y4
names: Similarity
messages: Belongs to the SIKE family.

419612:AMFR
gene id: 419612:AMFR
uniprot id: A0A8B8TJ41
uniprot id: A0A8B8TJ86
names: Subcellular Location Annotation
messages: Membrane

419612:RAP1GDS1
gene id: 419612:RAP1GDS1
uniprot id: A0A8B8RDP4
uniprot id: A0A8B8RDR1
uniprot id: A0A8B8RDT3
uniprot id: A0A8B8RDU6
uniprot id: A0A8B8RDW0
uniprot id: A0A8B8RFQ1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion

419612:S1PR1
gene id: 419612:S1PR1
uniprot id: A0A8B8TLV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:CDC34
gene id: 419612:CDC34
uniprot id: A0A8B8RVX6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:ABR
gene id: 419612:ABR
uniprot id: A0A8B6YFY8
uniprot id: A0A8B6YJN2
uniprot id: A0A8B8R5X9
uniprot id: A0A8B8R852
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

419612:TNF
gene id: 419612:TNF
uniprot id: S9XAI4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
messages: Homotrimer. Interacts with SPPL2B.
messages: Membrane
messages: O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid.
messages: Secreted
messages: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
messages: The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1.
messages: The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space.

419612:SLC39A13
gene id: 419612:SLC39A13
uniprot id: A0A8B8TQH9
uniprot id: A0A8B8TQI2
uniprot id: A0A8B8TQI3
uniprot id: A0A8B8TQI4
uniprot id: A0A8B8TQI7
uniprot id: A0A8B8TQI8
uniprot id: A0A8B8TR91
uniprot id: A0A8B8TRN6
uniprot id: A0A8B8TRP0
names: Subcellular Location Annotation
messages: Membrane

419612:CTSW
gene id: 419612:CTSW
uniprot id: A0A8B6YAM3
names: Similarity
messages: Belongs to the peptidase C1 family.

419612:TCTEX1D4
gene id: 419612:TCTEX1D4
uniprot id: A0A8B8U606
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

419612:PRND
gene id: 419612:PRND
uniprot id: A0A8B6YHN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Membrane

419612:ABCC9
gene id: 419612:ABCC9
uniprot id: A0A8B8SET4
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

419612:ARL6IP4
gene id: 419612:ARL6IP4
uniprot id: A0A8B6YAV9
uniprot id: A0A8B6YDG2
uniprot id: A0A8B7K5M0
uniprot id: A0A8B7K5P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

419612:INPPL1
gene id: 419612:INPPL1
uniprot id: A0A8B8TS73
uniprot id: A0A8B8TS79
uniprot id: A0A8B8TTA9
names: Similarity
names: Subcellular Location Annotation
messages: Basal cell membrane
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium
messages: spindle pole

419612:VXN
gene id: 419612:VXN
uniprot id: A0A8B6YN92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vexin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus

419612:LOC102506668
gene id: 419612:LOC102506668
uniprot id: A0A8B7KCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RAP2A
gene id: 419612:RAP2A
uniprot id: A0A8B6YR69
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

419612:EHD1
gene id: 419612:EHD1
uniprot id: A0A8B8TTN0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

419612:SLC20A2
gene id: 419612:SLC20A2
uniprot id: A0A8B8S3Y4
uniprot id: A0A8B8S3Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sodium-phosphate symporter.

419612:CHRND
gene id: 419612:CHRND
uniprot id: A0A8B6YPX2
uniprot id: A0A8B8T2A5
uniprot id: A0A8B8T350
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:CHMP4B
gene id: 419612:CHMP4B
uniprot id: A0A8B6YAY1
names: Similarity
messages: Belongs to the SNF7 family.

419612:GMDS
gene id: 419612:GMDS
uniprot id: A0A8B8RK03
uniprot id: A0A8B8RLS9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

419612:BZW1
gene id: 419612:BZW1
uniprot id: A0A8B8T1M3
uniprot id: A0A8B8T208
names: Similarity
messages: Belongs to the BZW family.

419612:CD63
gene id: 419612:CD63
uniprot id: A0A8B8U454
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Cell surface
messages: Endosome membrane
messages: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome
messages: Membrane
messages: extracellular exosome
messages: multivesicular body

419612:SAXO1
gene id: 419612:SAXO1
uniprot id: A0A8B6YBG2
uniprot id: A0A8B8SUA6
names: Similarity
messages: Belongs to the FAM154 family.

419612:LOC102512101
gene id: 419612:LOC102512101
uniprot id: A0A8B6YRT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:HAO2
gene id: 419612:HAO2
uniprot id: A0A8B6YG72
uniprot id: A0A8B7KBJ6
uniprot id: A0A8B8TKQ1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

419612:MYT1
gene id: 419612:MYT1
uniprot id: A0A8B8RHX3
uniprot id: A0A8B8RHX8
uniprot id: A0A8B8RHX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

419612:DGUOK
gene id: 419612:DGUOK
uniprot id: A0A8B6Y7H9
uniprot id: A0A8B8UHE5
names: Similarity
messages: Belongs to the DCK/DGK family.

419612:LOC116665933
gene id: 419612:LOC116665933
uniprot id: A0A8B8TMA2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

419612:RARRES1
gene id: 419612:RARRES1
uniprot id: A0A8B8TGN2
uniprot id: A0A8B8THX3
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

419612:XG
gene id: 419612:XG
uniprot id: A0A8B7KC80
uniprot id: A0A8B7KDB3
uniprot id: A0A8B7KEB6
uniprot id: A0A8B8SMW8
uniprot id: A0A8B8SP03
names: Similarity
messages: Belongs to the CD99 family.

419612:EXOSC3
gene id: 419612:EXOSC3
uniprot id: A0A8B8SV00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm
messages: nucleolus

419612:LOC116668627
gene id: 419612:LOC116668627
uniprot id: A0A8B8UD98
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

419612:MAD1L1
gene id: 419612:MAD1L1
uniprot id: A0A8B8RCS2
uniprot id: A0A8B8RCS3
uniprot id: A0A8B8RCS7
uniprot id: A0A8B8RET2
uniprot id: A0A8B8RFB0
names: Similarity
messages: Belongs to the MAD1 family.

419612:MAGOHB
gene id: 419612:MAGOHB
uniprot id: A0A8B6YNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

419612:ARPC5
gene id: 419612:ARPC5
uniprot id: A0A8B8RQ27
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

419612:LOC102518223
gene id: 419612:LOC102518223
uniprot id: A0A8B8T648
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RAN
gene id: 419612:RAN
uniprot id: A0A8B8SCK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

419612:SARAF
gene id: 419612:SARAF
uniprot id: A0A8B6YBI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Interacts with STIM1; the interaction is inhibit by th interaction of STIM1 with EFHB.
messages: Membrane
messages: Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.

419612:PRDM16
gene id: 419612:PRDM16
uniprot id: A0A8B8U8F7
uniprot id: A0A8B8U9A7
uniprot id: A0A8B8U9F0
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102509477
gene id: 419612:LOC102509477
uniprot id: A0A8B8SLY9
uniprot id: A0A8B8SP49
names: Subcellular Location Annotation
messages: Nucleus

419612:GLYATL3
gene id: 419612:GLYATL3
uniprot id: A0A8B6YKV3
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

419612:PLA2G12A
gene id: 419612:PLA2G12A
uniprot id: A0A8B8RK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

419612:ABCC2
gene id: 419612:ABCC2
uniprot id: A0A8B6YDR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

419612:SFT2D1
gene id: 419612:SFT2D1
uniprot id: A0A8B7KAJ8
uniprot id: A0A8B8TGA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

419612:ING5
gene id: 419612:ING5
uniprot id: A0A8B8T343
uniprot id: A0A8B8T3V8
uniprot id: A0A8B8T3W8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

419612:TAS1R3
gene id: 419612:TAS1R3
uniprot id: A0A8B8U856
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:TLR10
gene id: 419612:TLR10
uniprot id: A0A8B8UBX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

419612:LMBR1L
gene id: 419612:LMBR1L
uniprot id: A0A8B7K555
uniprot id: A0A8B8U231
uniprot id: A0A8B8U2K6
uniprot id: A0A8B8U333
uniprot id: A0A8B8U3B1
names: Similarity
messages: Belongs to the LIMR family.

419612:LOC102520945
gene id: 419612:LOC102520945
uniprot id: A0A8B7KGW5
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:NKX2-8
gene id: 419612:NKX2-8
uniprot id: A0A8B8T768
names: Subcellular Location Annotation
messages: Nucleus

419612:UTP23
gene id: 419612:UTP23
uniprot id: A0A8B6YHC4
names: Subcellular Location Annotation
messages: nucleolus

419612:SNU13
gene id: 419612:SNU13
uniprot id: A0A8B7KHR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

419612:DSC1
gene id: 419612:DSC1
uniprot id: A0A8B7KCI4
uniprot id: A0A8B8S0B8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

419612:SLC25A28
gene id: 419612:SLC25A28
uniprot id: A0A8B6YHU7
uniprot id: A0A8B8TYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:C3AR1
gene id: 419612:C3AR1
uniprot id: A0A8B7KET3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

419612:STAM
gene id: 419612:STAM
uniprot id: A0A8B7KF43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

419612:RPL22
gene id: 419612:RPL22
uniprot id: A0A8B6YD26
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

419612:SMG6
gene id: 419612:SMG6
uniprot id: A0A8B8R5S8
uniprot id: A0A8B8R5Z4
uniprot id: A0A8B8R7Z8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini.
messages: Plays a role in nonsense-mediated mRNA decay.
messages: The PINc domain confers endonuclease activity and is expected to bind the catalytic metal ion.
messages: cytosol
messages: nucleolus
messages: telomere

419612:LOC102510557
gene id: 419612:LOC102510557
uniprot id: A0A8B6Y841
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

419612:LOC116660505
gene id: 419612:LOC116660505
uniprot id: A0A8B8S756
uniprot id: A0A8B8S759
uniprot id: A0A8B8S761
uniprot id: A0A8B8S8G2
uniprot id: A0A8B8S8M3
uniprot id: A0A8B8S9D1
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

419612:ENPP1
gene id: 419612:ENPP1
uniprot id: A0A8B8TF14
uniprot id: A0A8B8TGD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Secreted

419612:LOC102523466
gene id: 419612:LOC102523466
uniprot id: A0A8B8SJC5
names: Similarity
messages: Belongs to the yippee family.

419612:SPEM3
gene id: 419612:SPEM3
uniprot id: A0A8B8UJ21
names: Subcellular Location Annotation
messages: Membrane

419612:REXO4
gene id: 419612:REXO4
uniprot id: A0A8B8SYL1
names: Similarity
messages: Belongs to the REXO4 family.

419612:CNN2
gene id: 419612:CNN2
uniprot id: A0A8B8RXK1
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

419612:PDCD10
gene id: 419612:PDCD10
uniprot id: A0A8B6YEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

419612:LOC106729612
gene id: 419612:LOC106729612
uniprot id: A0A8B8TJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

419612:PACS2
gene id: 419612:PACS2
uniprot id: A0A8B8T922
uniprot id: A0A8B8T923
uniprot id: A0A8B8T967
uniprot id: A0A8B8T9I8
uniprot id: A0A8B8TA37
names: Similarity
messages: Belongs to the PACS family.

419612:GADD45A
gene id: 419612:GADD45A
uniprot id: A0A8B8U878
names: Similarity
messages: Belongs to the GADD45 family.

419612:RPS17
gene id: 419612:RPS17
uniprot id: A0A8B6YMM7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

419612:HSPB3
gene id: 419612:HSPB3
uniprot id: S9WNM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Nucleus

419612:GPRIN1
gene id: 419612:GPRIN1
uniprot id: A0A8B8RSJ9
names: Function
messages: May be involved in neurite outgrowth.

419612:APEX2
gene id: 419612:APEX2
uniprot id: S9XFP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

419612:NCAPH
gene id: 419612:NCAPH
uniprot id: A0A8B6Y8R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

419612:LOC102514009
gene id: 419612:LOC102514009
uniprot id: A0A8B6Y772
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MZT1
gene id: 419612:MZT1
uniprot id: A0A8B8UEP0
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

419612:ACTR3B
gene id: 419612:ACTR3B
uniprot id: A0A8B8T9L6
names: Similarity
messages: Belongs to the actin family.

419612:KCNK18
gene id: 419612:KCNK18
uniprot id: A0A8B6YFK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

419612:CDC14A
gene id: 419612:CDC14A
uniprot id: A0A8B6YL59
uniprot id: A0A8B8TLF9
uniprot id: A0A8B8TLG5
uniprot id: A0A8B8TLU5
uniprot id: A0A8B8TMP0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

419612:RDH16
gene id: 419612:RDH16
uniprot id: A0A8B6YH67
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:FAM110D
gene id: 419612:FAM110D
uniprot id: A0A8B8UBD6
names: Similarity
messages: Belongs to the FAM110 family.

419612:SST
gene id: 419612:SST
uniprot id: S9WR54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

419612:SEZ6
gene id: 419612:SEZ6
uniprot id: A0A8B7KA62
uniprot id: A0A8B8R667
uniprot id: A0A8B8R8X3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:PCBD2
gene id: 419612:PCBD2
uniprot id: A0A8B7K8T6
uniprot id: A0A8B8SR90
uniprot id: A0A8B8SR91
uniprot id: A0A8B8SRZ4
uniprot id: A0A8B8SSC2
uniprot id: A0A8B8ST40
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

419612:LOC116656626
gene id: 419612:LOC116656626
uniprot id: A0A8B7KCY2
names: Similarity
messages: Belongs to the peptidase C14A family.

419612:OBP2B
gene id: 419612:OBP2B
uniprot id: A0A8B8SU00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

419612:SMIM15
gene id: 419612:SMIM15
uniprot id: A0A8B8SG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

419612:SLC35B3
gene id: 419612:SLC35B3
uniprot id: A0A8B6YG57
uniprot id: A0A8B8RK97
uniprot id: A0A8B8RM15
uniprot id: A0A8B8RMI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

419612:ADSS1
gene id: 419612:ADSS1
uniprot id: A0A8B8T8Y1
uniprot id: A0A8B8T9E8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

419612:BAMBI
gene id: 419612:BAMBI
uniprot id: A0A8B8SI43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

419612:SLC16A7
gene id: 419612:SLC16A7
uniprot id: A0A8B7KI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

419612:SPARC
gene id: 419612:SPARC
uniprot id: A0A8B6Y6C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

419612:IL12RB2
gene id: 419612:IL12RB2
uniprot id: A0A8B8U768
uniprot id: A0A8B8U820
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

419612:LOC102513803
gene id: 419612:LOC102513803
uniprot id: A0A8B8RIG7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

419612:GABRG2
gene id: 419612:GABRG2
uniprot id: A0A8B6YPF2
uniprot id: A0A8B8RUH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:WAS
gene id: 419612:WAS
uniprot id: A0A8B8SLE0
uniprot id: A0A8B8SLF4
uniprot id: A0A8B8SMT0
names: Subcellular Location Annotation
messages: Nucleus

419612:FOXD2
gene id: 419612:FOXD2
uniprot id: A0A8B8U691
names: Subcellular Location Annotation
messages: Nucleus

419612:SPTAN1
gene id: 419612:SPTAN1
uniprot id: A0A8B8SWK4
uniprot id: A0A8B8SWL2
uniprot id: A0A8B8SWR2
uniprot id: A0A8B8SWR7
uniprot id: A0A8B8SWW4
uniprot id: A0A8B8SWX1
uniprot id: A0A8B8SX82
uniprot id: A0A8B8SXU4
uniprot id: A0A8B8SXV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

419612:LOC102508421
gene id: 419612:LOC102508421
uniprot id: A0A8B8TUC6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

419612:HSPA4L
gene id: 419612:HSPA4L
uniprot id: A0A8B8RMP9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

419612:PIR
gene id: 419612:PIR
uniprot id: A0A8B6YNT9
uniprot id: A0A8B7KI43
names: Similarity
messages: Belongs to the pirin family.

419612:LHPP
gene id: 419612:LHPP
uniprot id: A0A8B8TWB5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

419612:MYO7B
gene id: 419612:MYO7B
uniprot id: A0A8B8SYL6
uniprot id: A0A8B8SZ32
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

419612:ADORA2A
gene id: 419612:ADORA2A
uniprot id: S9YGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

419612:ATXN2
gene id: 419612:ATXN2
uniprot id: A0A8B8SA51
uniprot id: A0A8B8SA52
uniprot id: A0A8B8SA56
uniprot id: A0A8B8SA57
uniprot id: A0A8B8SBC3
uniprot id: A0A8B8SBC8
uniprot id: A0A8B8SBH2
uniprot id: A0A8B8SBH7
uniprot id: A0A8B8SCI1
uniprot id: A0A8B8SCI6
names: Similarity
messages: Belongs to the ataxin-2 family.

419612:BRAF
gene id: 419612:BRAF
uniprot id: A0A8B8TDK6
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

419612:TLL1
gene id: 419612:TLL1
uniprot id: A0A8B8RVA5
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:ATP5ME
gene id: 419612:ATP5ME
uniprot id: A0A8B8TZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

419612:PMEL
gene id: 419612:PMEL
uniprot id: A0A8B6YCA4
names: Similarity
messages: Belongs to the PMEL/NMB family.

419612:PARD3B
gene id: 419612:PARD3B
uniprot id: A0A8B8T1E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

419612:CEBPZ
gene id: 419612:CEBPZ
uniprot id: A0A8B6YDE3
names: Similarity
messages: Belongs to the CBF/MAK21 family.

419612:GATM
gene id: 419612:GATM
uniprot id: A0A8B8T5A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Homodimer.
messages: Mitochondrion inner membrane
messages: Transamidinase that catalyzes the transfer of the amidino group of L-arginine onto the amino moiety of acceptor metabolites such as glycine, beta-alanine, gamma-aminobutyric acid (GABA) and taurine yielding the corresponding guanidine derivatives. Catalyzes the rate-limiting step of creatine biosynthesis, namely the transfer of the amidino group from L-arginine to glycine to generate guanidinoacetate, which is then methylated by GAMT to form creatine. Provides creatine as a source for ATP generation in tissues with high energy demands, in particular skeletal muscle, heart and brain.

419612:LOC102506745
gene id: 419612:LOC102506745
uniprot id: A0A8B6YFP5
uniprot id: A0A8B8RAS5
uniprot id: A0A8B8RDE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

419612:CARM1
gene id: 419612:CARM1
uniprot id: A0A8B8RUB7
uniprot id: A0A8B8RVW7
names: Subcellular Location Annotation
messages: Nucleus

419612:EBP
gene id: 419612:EBP
uniprot id: A0A8B8SKT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:LOC116662038
gene id: 419612:LOC116662038
uniprot id: A0A8B8SMX9
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

419612:ADK
gene id: 419612:ADK
uniprot id: A0A8B6Y733
uniprot id: A0A8B6Y9E5
uniprot id: A0A8B8TYS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

419612:LSM14A
gene id: 419612:LSM14A
uniprot id: A0A8B8TIL2
uniprot id: A0A8B8TIN4
uniprot id: A0A8B8TJU1
names: Similarity
messages: Belongs to the LSM14 family.

419612:LOC102504018
gene id: 419612:LOC102504018
uniprot id: A0A8B7KEE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

419612:LOC102523731
gene id: 419612:LOC102523731
uniprot id: A0A8B6YB33
uniprot id: A0A8B7K5R3
uniprot id: A0A8B7K823
uniprot id: A0A8B8U667
uniprot id: A0A8B8U7A3
names: Similarity
messages: Belongs to the cytochrome P450 family.

419612:EEF1D
gene id: 419612:EEF1D
uniprot id: A0A8B8S1Q8
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

419612:ZYG11B
gene id: 419612:ZYG11B
uniprot id: A0A8B8U7I7
names: Similarity
messages: Belongs to the zyg-11 family.

419612:HTR1D
gene id: 419612:HTR1D
uniprot id: S9X4N7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1B.
messages: Membrane

419612:EPYC
gene id: 419612:EPYC
uniprot id: A0A8B6YBT6
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

419612:MRPL53
gene id: 419612:MRPL53
uniprot id: A0A8B6Y4G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

419612:DCC
gene id: 419612:DCC
uniprot id: A0A8B7K987
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

419612:TMPRSS6
gene id: 419612:TMPRSS6
uniprot id: A0A8B7K3T4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC102515967
gene id: 419612:LOC102515967
uniprot id: S9XBK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:EME2
gene id: 419612:EME2
uniprot id: A0A8B8RDH2
uniprot id: A0A8B8RG12
names: Similarity
messages: Belongs to the EME1/MMS4 family.

419612:LOC102504740
gene id: 419612:LOC102504740
uniprot id: A0A8B8SRV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:TMOD3
gene id: 419612:TMOD3
uniprot id: A0A8B8T4K2
names: Subcellular Location Annotation
messages: cytoskeleton

419612:CAT
gene id: 419612:CAT
uniprot id: A0A8B8TQ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

419612:LOC102504718
gene id: 419612:LOC102504718
uniprot id: A0A8B6YN06
uniprot id: A0A8B8TEI6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

419612:XIRP1
gene id: 419612:XIRP1
uniprot id: A0A8B8RCW4
names: Domain
names: Function
names: Similarity
messages: Belongs to the Xin family.
messages: Protects actin filaments from depolymerization.
messages: Xin repeats bind F-actin.

419612:SSBP3
gene id: 419612:SSBP3
uniprot id: A0A8B8U7J4
uniprot id: A0A8B8U7L6
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102519199
gene id: 419612:LOC102519199
uniprot id: A0A8B6YPZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:OPRK1
gene id: 419612:OPRK1
uniprot id: A0A8B8S7W8
uniprot id: A0A8B8S827
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with NHERF1. Interacts with GABARAPL1.
messages: Membrane

419612:SHCBP1
gene id: 419612:SHCBP1
uniprot id: A0A8B8TJZ7
names: Subcellular Location Annotation
messages: spindle

419612:SIAH1
gene id: 419612:SIAH1
uniprot id: A0A8B6YEC3
uniprot id: A0A8B8TIT5
uniprot id: S9WUI8
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

419612:YIPF2
gene id: 419612:YIPF2
uniprot id: A0A8B6YG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

419612:MXRA8
gene id: 419612:MXRA8
uniprot id: A0A8B8U9C3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:TH
gene id: 419612:TH
uniprot id: A0A8B8TVV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region
messages: synaptic vesicle

419612:SOX1
gene id: 419612:SOX1
uniprot id: A0A8B8UD44
uniprot id: A0A8B8UEG5
names: Subcellular Location Annotation
messages: Nucleus

419612:ABCA1
gene id: 419612:ABCA1
uniprot id: A0A8B7KA78
names: Subcellular Location Annotation
messages: Membrane

419612:SNX19
gene id: 419612:SNX19
uniprot id: A0A8B7K8I2
names: Similarity
messages: Belongs to the sorting nexin family.

419612:PTH2R
gene id: 419612:PTH2R
uniprot id: A0A8B6YDC3
names: Subcellular Location Annotation
messages: Membrane

419612:ACADSB
gene id: 419612:ACADSB
uniprot id: A0A8B6YJ06
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

419612:CHMP6
gene id: 419612:CHMP6
uniprot id: A0A8B8R3E0
uniprot id: A0A8B8R5Q8
names: Similarity
messages: Belongs to the SNF7 family.

419612:DCAF1
gene id: 419612:DCAF1
uniprot id: A0A8B8R8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus

419612:SLC6A11
gene id: 419612:SLC6A11
uniprot id: A0A8B8RA27
uniprot id: A0A8B8RCU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

419612:LOC102523470
gene id: 419612:LOC102523470
uniprot id: A0A8B6YMH4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

419612:CTBS
gene id: 419612:CTBS
uniprot id: A0A8B6YKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Lysosome

419612:CKAP5
gene id: 419612:CKAP5
uniprot id: A0A8B7K7Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOG/XMAP215 family.
messages: kinetochore

419612:ERGIC3
gene id: 419612:ERGIC3
uniprot id: A0A8B6YIX9
uniprot id: A0A8B7KEL0
uniprot id: A0A8B8RLR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

419612:TNFSF4
gene id: 419612:TNFSF4
uniprot id: A0A8B8RNU5
uniprot id: S9WT50
names: Similarity
messages: Belongs to the tumor necrosis factor family.

419612:GPSM2
gene id: 419612:GPSM2
uniprot id: A0A8B8TLY4
names: Similarity
messages: Belongs to the GPSM family.

419612:MLEC
gene id: 419612:MLEC
uniprot id: A0A8B6YDD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:SGSM3
gene id: 419612:SGSM3
uniprot id: A0A8B8U0U1
uniprot id: A0A8B8U0U4
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

419612:LOC106729620
gene id: 419612:LOC106729620
uniprot id: A0A8B8SCJ7
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

419612:NDRG4
gene id: 419612:NDRG4
uniprot id: A0A8B7KGJ8
uniprot id: A0A8B8TJB7
uniprot id: A0A8B8TJB8
uniprot id: A0A8B8TJC2
uniprot id: A0A8B8TJD2
uniprot id: A0A8B8TJD7
uniprot id: A0A8B8TJJ3
uniprot id: A0A8B8TJJ9
names: Similarity
messages: Belongs to the NDRG family.

419612:CACNA2D2
gene id: 419612:CACNA2D2
uniprot id: A0A8B8R8L1
uniprot id: A0A8B8R8L3
uniprot id: A0A8B8R8Q7
uniprot id: A0A8B8RAQ3
uniprot id: A0A8B8RAQ8
uniprot id: A0A8B8RBE3
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

419612:DZIP1L
gene id: 419612:DZIP1L
uniprot id: A0A8B8TN89
uniprot id: A0A8B8TN99
uniprot id: A0A8B8TPD8
uniprot id: A0A8B8TPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: cilium basal body

419612:LOC102519250
gene id: 419612:LOC102519250
uniprot id: A0A8B6YIB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

419612:ADGRD2
gene id: 419612:ADGRD2
uniprot id: A0A8B8SYV8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:GCNT1
gene id: 419612:GCNT1
uniprot id: A0A8B8SUR6
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

419612:GPRIN2
gene id: 419612:GPRIN2
uniprot id: A0A8B8TYY7
uniprot id: A0A8B8U099
names: Function
messages: May be involved in neurite outgrowth.

419612:FZD6
gene id: 419612:FZD6
uniprot id: A0A8B8S050
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:FBP1
gene id: 419612:FBP1
uniprot id: A0A8B8SUA0
names: Similarity
messages: Belongs to the FBPase class 1 family.

419612:LOC116662033
gene id: 419612:LOC116662033
uniprot id: A0A8B8SLG9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

419612:TXNRD1
gene id: 419612:TXNRD1
uniprot id: A0A8B8U431
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

419612:LOC102523368
gene id: 419612:LOC102523368
uniprot id: A0A8B8SAF7
names: Similarity
messages: Belongs to the NUT family.

419612:KRT17
gene id: 419612:KRT17
uniprot id: A0A8B7K6B3
uniprot id: A0A8B8UHI3
uniprot id: A0A8B8UI22
names: Similarity
messages: Belongs to the intermediate filament family.

419612:FGF12
gene id: 419612:FGF12
uniprot id: A0A8B8T715
uniprot id: A0A8B8T7Q9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

419612:DGKG
gene id: 419612:DGKG
uniprot id: A0A8B6YJ30
uniprot id: A0A8B6YJ55
uniprot id: A0A8B7KCQ4
uniprot id: A0A8B8T8S7
uniprot id: A0A8B8T8T6
uniprot id: A0A8B8T905
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

419612:LOC102507143
gene id: 419612:LOC102507143
uniprot id: S9XF70
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Belongs to the intercrine gamma family.

419612:LOC102521492
gene id: 419612:LOC102521492
uniprot id: A0A8B6YF94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:P4HB
gene id: 419612:P4HB
uniprot id: A0A8B8R337
uniprot id: A0A8B8R5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

419612:MRE11
gene id: 419612:MRE11
uniprot id: A0A8B6YNA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

419612:RAB33A
gene id: 419612:RAB33A
uniprot id: A0A8B6YN84
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

419612:AP4S1
gene id: 419612:AP4S1
uniprot id: A0A8B8T631
uniprot id: A0A8B8T657
uniprot id: A0A8B8T6E7
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

419612:LOC102504304
gene id: 419612:LOC102504304
uniprot id: A0A8B8SDZ2
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

419612:SLC39A10
gene id: 419612:SLC39A10
uniprot id: A0A8B7K4J9
names: Subcellular Location Annotation
messages: Membrane

419612:BAZ2B
gene id: 419612:BAZ2B
uniprot id: A0A8B6Y8T7
uniprot id: A0A8B8SZH2
uniprot id: A0A8B8SZH7
uniprot id: A0A8B8SZH9
uniprot id: A0A8B8SZI5
uniprot id: A0A8B8SZY5
uniprot id: A0A8B8SZZ2
uniprot id: A0A8B8SZZ3
uniprot id: A0A8B8SZZ7
uniprot id: A0A8B8SZZ9
uniprot id: A0A8B8T006
uniprot id: A0A8B8T012
uniprot id: A0A8B8T0F7
uniprot id: A0A8B8T0H1
uniprot id: A0A8B8T0H6
uniprot id: A0A8B8T0I4
names: Similarity
messages: Belongs to the WAL family.

419612:PDGFRL
gene id: 419612:PDGFRL
uniprot id: A0A8B6YPA4
uniprot id: A0A8B8S4E6
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.

419612:TMTC4
gene id: 419612:TMTC4
uniprot id: A0A8B8UDE8
uniprot id: A0A8B8UER5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

419612:RAD54L2
gene id: 419612:RAD54L2
uniprot id: A0A8B8R8H3
uniprot id: T0NHA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

419612:B4GALNT3
gene id: 419612:B4GALNT3
uniprot id: A0A8B8SGL1
uniprot id: A0A8B8SJ57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

419612:LOC102518299
gene id: 419612:LOC102518299
uniprot id: A0A8B6Y636
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:AMDHD2
gene id: 419612:AMDHD2
uniprot id: A0A8B8RDR6
uniprot id: A0A8B8RDR7
uniprot id: A0A8B8RDX5
uniprot id: A0A8B8RGA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.

419612:TARS3
gene id: 419612:TARS3
uniprot id: A0A8B8S5Q2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

419612:PON3
gene id: 419612:PON3
uniprot id: A0A8B6Y9Q2
uniprot id: A0A8B8TCA3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

419612:ASXL3
gene id: 419612:ASXL3
uniprot id: A0A8B8S0F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

419612:NDUFB6
gene id: 419612:NDUFB6
uniprot id: A0A8B8SU54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

419612:LOC102507410
gene id: 419612:LOC102507410
uniprot id: A0A8B6YNJ7
uniprot id: A0A8B8SJN0
names: Similarity
messages: Belongs to the DEAD box helicase family.

419612:BRIX1
gene id: 419612:BRIX1
uniprot id: A0A8B7KIE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

419612:ME2
gene id: 419612:ME2
uniprot id: A0A8B8SB43
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

419612:ATIC
gene id: 419612:ATIC
uniprot id: A0A8B8T0M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PurH family.
messages: cytosol

419612:ASIP
gene id: 419612:ASIP
uniprot id: A0A8B6YKU1
names: Subcellular Location Annotation
messages: Secreted

419612:FAM216B
gene id: 419612:FAM216B
uniprot id: A0A8B7K498
uniprot id: S9YTA6
names: Similarity
messages: Belongs to the FAM216 family.

419612:FAM13A
gene id: 419612:FAM13A
uniprot id: A0A8B8UIZ0
names: Similarity
messages: Belongs to the FAM13 family.

419612:FAM166B
gene id: 419612:FAM166B
uniprot id: A0A8B6YI88
uniprot id: A0A8B7KE19
names: Similarity
messages: Belongs to the CIMIP2 family.

419612:GOLM1
gene id: 419612:GOLM1
uniprot id: A0A8B8STD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

419612:LOC116663073
gene id: 419612:LOC116663073
uniprot id: A0A8B8STQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

419612:DAPK2
gene id: 419612:DAPK2
uniprot id: A0A8B8T3M4
uniprot id: A0A8B8T4F3
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:MRI1
gene id: 419612:MRI1
uniprot id: A0A8B8RTU0
uniprot id: A0A8B8RTU4
uniprot id: A0A8B8RUV6
uniprot id: A0A8B8RVP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

419612:LOC106729490
gene id: 419612:LOC106729490
uniprot id: A0A8B7K9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

419612:NCAPH2
gene id: 419612:NCAPH2
uniprot id: A0A8B8U1R3
uniprot id: A0A8B8U1R7
uniprot id: A0A8B8U1S0
uniprot id: A0A8B8U2S6
uniprot id: A0A8B8U307
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

419612:OSGEPL1
gene id: 419612:OSGEPL1
uniprot id: A0A8B6YJM8
uniprot id: A0A8B8T0L4
uniprot id: A0A8B8T0L5
uniprot id: A0A8B8T104
uniprot id: A0A8B8T142
uniprot id: A0A8B8T1I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

419612:BPI
gene id: 419612:BPI
uniprot id: A0A8B6YKB1
uniprot id: A0A8B8RJP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

419612:NPM3
gene id: 419612:NPM3
uniprot id: A0A8B6YF21
names: Similarity
messages: Belongs to the nucleoplasmin family.

419612:KAT8
gene id: 419612:KAT8
uniprot id: A0A8B6YCV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

419612:AIF1L
gene id: 419612:AIF1L
uniprot id: A0A8B8SXC2
uniprot id: A0A8B8SY73
names: Subcellular Location Annotation
messages: ruffle membrane

419612:LOC102513932
gene id: 419612:LOC102513932
uniprot id: A0A8B6Y8G9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

419612:LOC102508477
gene id: 419612:LOC102508477
uniprot id: A0A8B7KFA3
names: Similarity
messages: Belongs to the CD200R family.

419612:IRGQ
gene id: 419612:IRGQ
uniprot id: A0A8B8THS8
uniprot id: A0A8B8TJ05
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

419612:CHD1
gene id: 419612:CHD1
uniprot id: A0A8B8SQ48
uniprot id: A0A8B8SQ68
uniprot id: A0A8B8SRC1
uniprot id: A0A8B8SS57
names: Subcellular Location Annotation
messages: Nucleus

419612:CFH
gene id: 419612:CFH
uniprot id: A0A8B8RZA2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:CDH7
gene id: 419612:CDH7
uniprot id: A0A8B8S8S4
uniprot id: A0A8B8S8S9
uniprot id: A0A8B8SA19
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

419612:MYO15B
gene id: 419612:MYO15B
uniprot id: A0A8B8R451
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:DHFR
gene id: 419612:DHFR
uniprot id: A0A8B8SLQ7
uniprot id: A0A8B8SMV4
uniprot id: S9XWS8
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

419612:HPSE2
gene id: 419612:HPSE2
uniprot id: A0A8B8TXI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

419612:NSUN3
gene id: 419612:NSUN3
uniprot id: A0A8B6YJJ4
uniprot id: A0A8B8SU98
uniprot id: A0A8B8SUI0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

419612:PDE4C
gene id: 419612:PDE4C
uniprot id: A0A8B8RT65
uniprot id: A0A8B8RT66
uniprot id: A0A8B8RU49
uniprot id: A0A8B8RUT4
uniprot id: A0A8B8RV42
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

419612:GALK2
gene id: 419612:GALK2
uniprot id: A0A8B6YNT6
uniprot id: A0A8B6YQX6
uniprot id: A0A8B8T4B2
uniprot id: A0A8B8T4M8
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

419612:DARS1
gene id: 419612:DARS1
uniprot id: A0A8B7K686
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

419612:TAFA1
gene id: 419612:TAFA1
uniprot id: A0A8B8R7P6
uniprot id: A0A8B8R7P7
uniprot id: A0A8B8R7Q1
names: Similarity
messages: Belongs to the TAFA family.

419612:CPSF4
gene id: 419612:CPSF4
uniprot id: A0A8B8RCH0
uniprot id: A0A8B8RCH1
uniprot id: A0A8B8RCI3
uniprot id: A0A8B8REI4
uniprot id: A0A8B8REI7
uniprot id: A0A8B8RF06
uniprot id: A0A8B8RF11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

419612:HECTD1
gene id: 419612:HECTD1
uniprot id: A0A8B8T616
uniprot id: A0A8B8T640
uniprot id: A0A8B8T6C8
uniprot id: A0A8B8T6Q7
uniprot id: A0A8B8T6X2
names: Function
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

419612:SERPINI1
gene id: 419612:SERPINI1
uniprot id: A0A8B6YEJ1
names: Similarity
messages: Belongs to the serpin family.

419612:HSPA4
gene id: 419612:HSPA4
uniprot id: A0A8B6YES8
uniprot id: A0A8B8SSZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

419612:CRTC3
gene id: 419612:CRTC3
uniprot id: A0A8B8S4T3
uniprot id: A0A8B8S6T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

419612:EIF3B
gene id: 419612:EIF3B
uniprot id: A0A8B8REU3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Also interacts with UPF2. Interacts with METTL3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: The RRM domain mediates interaction with EIF3J.

419612:NCAPD3
gene id: 419612:NCAPD3
uniprot id: A0A8B8SDM5
uniprot id: A0A8B8SDN1
uniprot id: A0A8B8SET6
uniprot id: A0A8B8SEY6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the condensin-2 complex.
messages: Nucleus
messages: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.

419612:SESN3
gene id: 419612:SESN3
uniprot id: A0A8B8TPK5
uniprot id: A0A8B8TQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

419612:LOC116667610
gene id: 419612:LOC116667610
uniprot id: A0A8B8U3K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MB21D2
gene id: 419612:MB21D2
uniprot id: A0A8B6YA25
uniprot id: A0A8B8T6Z4
names: Similarity
messages: Belongs to the mab-21 family.

419612:HEXD
gene id: 419612:HEXD
uniprot id: A0A8B8UKM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

419612:VPS52
gene id: 419612:VPS52
uniprot id: A0A8B6YBK2
uniprot id: A0A8B8RL83
uniprot id: A0A8B8RN01
names: Similarity
messages: Belongs to the VPS52 family.

419612:LOC116664796
gene id: 419612:LOC116664796
uniprot id: A0A8B8TAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

419612:LOC106730957
gene id: 419612:LOC106730957
uniprot id: A0A8B8U0C7
uniprot id: A0A8B8U0D0
uniprot id: A0A8B8U1N0
names: Similarity
messages: Belongs to the apolipoprotein L family.

419612:SLC26A2
gene id: 419612:SLC26A2
uniprot id: A0A8B8STX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sulfate transporter which mediates sulfate uptake into chondrocytes in order to maintain adequate sulfation of proteoglycans which is needed for cartilage development. Mediates electroneutral anion exchange of sulfate ions for oxalate ions, sulfate and oxalate ions for chloride and/or hydroxyl ions and chloride ions for bromide, iodide and nitrate ions. The coupling of sulfate transport to both hydroxyl and chloride ions likely serves to ensure transport at both acidic pH when most sulfate uptake is mediated by sulfate-hydroxide exchange and alkaline pH when most sulfate uptake is mediated by sulfate-chloride exchange. Essential for chondrocyte proliferation, differentiation and cell size expansion.

419612:PIGC
gene id: 419612:PIGC
uniprot id: T0MKC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

419612:CELF5
gene id: 419612:CELF5
uniprot id: A0A8B8RV97
uniprot id: A0A8B8RWE9
uniprot id: A0A8B8RWF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

419612:TIMM21
gene id: 419612:TIMM21
uniprot id: A0A8B6YI70
uniprot id: A0A8B8SAR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane
messages: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.

419612:PGC
gene id: 419612:PGC
uniprot id: A0A8B6YKW9
names: Similarity
messages: Belongs to the peptidase A1 family.

419612:ZPR1
gene id: 419612:ZPR1
uniprot id: A0A8B7K432
uniprot id: A0A8B8SGT7
names: Similarity
messages: Belongs to the ZPR1 family.

419612:LOC102515788
gene id: 419612:LOC102515788
uniprot id: A0A8B6YGP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

419612:MASTL
gene id: 419612:MASTL
uniprot id: A0A8B6YLS6
uniprot id: A0A8B6YM04
uniprot id: A0A8B8SI94
uniprot id: A0A8B8SKQ6
names: Subcellular Location Annotation
messages: Nucleus
messages: centrosome

419612:MKS1
gene id: 419612:MKS1
uniprot id: A0A8B8UIC8
uniprot id: A0A8B8UIU9
uniprot id: A0A8B8UJM2
names: Subcellular Location Annotation
messages: cilium basal body

419612:SEC16A
gene id: 419612:SEC16A
uniprot id: A0A8B8SYI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

419612:DPYSL3
gene id: 419612:DPYSL3
uniprot id: A0A8B6YLJ4
uniprot id: A0A8B6YLL6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

419612:NDUFAF3
gene id: 419612:NDUFAF3
uniprot id: A0A8B8R916
uniprot id: A0A8B8RB23
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

419612:USP49
gene id: 419612:USP49
uniprot id: A0A8B8RP40
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

419612:GPR83
gene id: 419612:GPR83
uniprot id: A0A8B6YPU5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:LOC102512836
gene id: 419612:LOC102512836
uniprot id: A0A8B8T5H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:AK1
gene id: 419612:AK1
uniprot id: A0A8B6YCS7
uniprot id: A0A8B8SWR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

419612:APOA4
gene id: 419612:APOA4
uniprot id: A0A8B6YB24
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

419612:LOC102505542
gene id: 419612:LOC102505542
uniprot id: A0A8B6YGJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:IAPP
gene id: 419612:IAPP
uniprot id: A0A8B8SEX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Secreted
messages: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.

419612:LOC102510596
gene id: 419612:LOC102510596
uniprot id: A0A8B8S3X2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

419612:GPLD1
gene id: 419612:GPLD1
uniprot id: A0A8B8RKL0
uniprot id: A0A8B8RKW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPLD1 family.
messages: Secreted

419612:AS3MT
gene id: 419612:AS3MT
uniprot id: A0A8B8TX75
uniprot id: A0A8B8TX76
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

419612:ZEB2
gene id: 419612:ZEB2
uniprot id: A0A8B8SZ22
uniprot id: A0A8B8SZ28
uniprot id: A0A8B8SZ40
uniprot id: A0A8B8SZK3
uniprot id: A0A8B8T050
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

419612:RBPMS2
gene id: 419612:RBPMS2
uniprot id: A0A8B8T4C0
names: Subcellular Location Annotation
messages: Cytoplasm

419612:LOC102523159
gene id: 419612:LOC102523159
uniprot id: A0A8B8S994
names: Similarity
messages: Belongs to the VPS26 family.

419612:DEFB127
gene id: 419612:DEFB127
uniprot id: A0A8B6YR34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

419612:NDUFA7
gene id: 419612:NDUFA7
uniprot id: A0A8B6YFI1
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

419612:LOC102519225
gene id: 419612:LOC102519225
uniprot id: A0A8B8UEP8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

419612:RNPC3
gene id: 419612:RNPC3
uniprot id: A0A8B7KH95
uniprot id: A0A8B8TLI1
uniprot id: A0A8B8TLW4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Found in a complex with m(7)G-capped U12 snRNA. Interacts with PDCD7.
messages: Nucleus
messages: Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.

419612:FFAR3
gene id: 419612:FFAR3
uniprot id: A0A8B8TPN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:PRLHR
gene id: 419612:PRLHR
uniprot id: S9WE89
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:RAMP3
gene id: 419612:RAMP3
uniprot id: A0A8B8TDE7
uniprot id: A0A8B8TEM3
names: Similarity
messages: Belongs to the RAMP family.

419612:LOC102516982
gene id: 419612:LOC102516982
uniprot id: A0A8B8TRT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:HTR7
gene id: 419612:HTR7
uniprot id: A0A8B6YEG2
uniprot id: A0A8B6YEG9
uniprot id: A0A8B8TY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:TAF15
gene id: 419612:TAF15
uniprot id: A0A8B8UIE6
uniprot id: A0A8B8UIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

419612:TENM3
gene id: 419612:TENM3
uniprot id: A0A8B8S2F0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HHIP family.
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:NMNAT3
gene id: 419612:NMNAT3
uniprot id: A0A8B8TM97
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

419612:SLC26A7
gene id: 419612:SLC26A7
uniprot id: A0A8B8S0A5
uniprot id: A0A8B8S1L3
uniprot id: A0A8B8S1V6
uniprot id: A0A8B8S1W8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:PHTF2
gene id: 419612:PHTF2
uniprot id: A0A8B8TCS0
uniprot id: A0A8B8TCS2
uniprot id: A0A8B8TCT4
uniprot id: A0A8B8TCU0
uniprot id: A0A8B8TD04
uniprot id: A0A8B8TE12
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102505260
gene id: 419612:LOC102505260
uniprot id: A0A8B8SAZ9
uniprot id: A0A8B8SBZ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SLC19A1
gene id: 419612:SLC19A1
uniprot id: A0A8B8TSJ5
uniprot id: A0A8B8TSY5
uniprot id: A0A8B8TTX8
uniprot id: A0A8B8TU88
uniprot id: A0A8B8TUD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Cell membrane
messages: Transporter that mediates the import of reduced folates.

419612:RETREG3
gene id: 419612:RETREG3
uniprot id: A0A8B6Y8H9
uniprot id: A0A8B7K5X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:LOC116666582
gene id: 419612:LOC116666582
uniprot id: A0A8B8TVI1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

419612:COQ10B
gene id: 419612:COQ10B
uniprot id: A0A8B6Y8I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

419612:LOC116668141
gene id: 419612:LOC116668141
uniprot id: A0A8B8U8L5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

419612:FAM167B
gene id: 419612:FAM167B
uniprot id: S9YTK4
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

419612:TOP3A
gene id: 419612:TOP3A
uniprot id: A0A8B8UK96
uniprot id: A0A8B8UKA0
uniprot id: A0A8B8UKC5
uniprot id: A0A8B8UKF2
uniprot id: A0A8B8UL01
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

419612:SELENOI
gene id: 419612:SELENOI
uniprot id: A0A8B6YL78
uniprot id: A0A8B7KD87
uniprot id: A0A8B8UER4
uniprot id: A0A8B8UFJ5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

419612:UTP25
gene id: 419612:UTP25
uniprot id: A0A8B6YD50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

419612:SVEP1
gene id: 419612:SVEP1
uniprot id: A0A8B8SVN3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

419612:PLIN3
gene id: 419612:PLIN3
uniprot id: A0A8B8RW07
uniprot id: A0A8B8RWQ8
names: Similarity
messages: Belongs to the perilipin family.

419612:SLC7A4
gene id: 419612:SLC7A4
uniprot id: A0A8B8SCP8
uniprot id: A0A8B8SCQ7
names: Subcellular Location Annotation
messages: Membrane

419612:BRCA1
gene id: 419612:BRCA1
uniprot id: A0A8B7K3Y1
uniprot id: A0A8B7K5W3
uniprot id: A0A8B8R589
uniprot id: A0A8B8R590
uniprot id: A0A8B8R594
uniprot id: A0A8B8R5G7
uniprot id: A0A8B8R7Y9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Regulates centrosomal microtubule nucleation. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Required for FANCD2 targeting to sites of DNA damage. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation. Contributes to homologous recombination repair (HRR) via its direct interaction with PALB2, fine-tunes recombinational repair partly through its modulatory role in the PALB2-dependent loading of BRCA2-RAD51 repair machinery at DNA breaks. Component of the BRCA1-RBBP8 complex which regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage via BRCA1-mediated ubiquitination of RBBP8. Acts as a transcriptional activator.
messages: Heterodimer with BARD1. Part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the MRE11-RAD50-NBN protein (MRN) complex. This association could be a dynamic process changing throughout the cell cycle and within subnuclear domains. Component of the BRCA1-A complex, at least composed of BRCA1, BARD1, UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Interacts (via the BRCT domains) with ABRAXAS1 (phosphorylated form); this is important for recruitment to sites of DNA damage. Can form a heterotetramer with two molecules of ABRAXAS1 (phosphorylated form). Component of the BRCA1-RBBP8 complex. Interacts (via the BRCT domains) with RBBP8 ('Ser-327' phosphorylated form); the interaction ubiquitinates RBBP8, regulates CHEK1 activation, and involves RBBP8 in BRCA1-dependent G2/M checkpoint control on DNA damage. Associates with RNA polymerase II holoenzyme. Interacts with SMC1A, NELFB, DCLRE1C, CLSPN. CHEK1, CHEK2, BAP1, BRCC3, UBXN1 and PCLAF. Interacts (via BRCT domains) with BRIP1 (phosphorylated form). Interacts with FANCD2 (ubiquitinated form). Interacts with H2AX (phosphorylated on 'Ser-140'). Interacts (via the BRCT domains) with ACACA (phosphorylated form); the interaction prevents dephosphorylation of ACACA. Part of a BRCA complex containing BRCA1, BRCA2 and PALB2. Interacts directly with PALB2; the interaction is essential for its function in HRR. Interacts directly with BRCA2; the interaction occurs only in the presence of PALB2 which serves as the bridging protein. Interacts (via the BRCT domains) with LMO4; the interaction represses the transcriptional activity of BRCA1. Interacts (via the BRCT domains) with CCAR2 (via N-terminus); the interaction represses the transcriptional activator activity of BRCA1. Interacts with EXD2. Interacts (via C-terminus) with DHX9; this interaction is direct and links BRCA1 to the RNA polymerase II holoenzyme.
messages: Nucleus

419612:SEC23A
gene id: 419612:SEC23A
uniprot id: A0A8B8T704
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

419612:CHD2
gene id: 419612:CHD2
uniprot id: A0A8B8S5P7
names: Subcellular Location Annotation
messages: Nucleus

419612:CLRN2
gene id: 419612:CLRN2
uniprot id: A0A8B6YMU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

419612:NAALADL2
gene id: 419612:NAALADL2
uniprot id: A0A8B8TCK2
uniprot id: A0A8B8TCM2
uniprot id: A0A8B8TCN2
uniprot id: A0A8B8TCN7
uniprot id: A0A8B8TCV6
uniprot id: A0A8B8TDW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Membrane

419612:LOC102507661
gene id: 419612:LOC102507661
uniprot id: A0A8B8SXE2
uniprot id: A0A8B8SYL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.
messages: Mitochondrion inner membrane

419612:SSBP4
gene id: 419612:SSBP4
uniprot id: A0A8B8RT71
uniprot id: A0A8B8RU53
uniprot id: A0A8B8RUT7
uniprot id: A0A8B8RV46
names: Subcellular Location Annotation
messages: Nucleus

419612:MCPH1
gene id: 419612:MCPH1
uniprot id: A0A8B8S2G9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.
messages: Interacts with CDC27 and maybe other components of the APC/C complex. Interacts with histone variant H2AX under DNA damage conditions.
messages: centrosome

419612:UBA1
gene id: 419612:UBA1
uniprot id: A0A8B8SKK3
uniprot id: A0A8B8SLV9
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

419612:UMODL1
gene id: 419612:UMODL1
uniprot id: A0A8B8RHP6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102521879
gene id: 419612:LOC102521879
uniprot id: A0A8B6YQC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:SLC66A1
gene id: 419612:SLC66A1
uniprot id: A0A8B7KCA1
uniprot id: A0A8B8U9F3
uniprot id: A0A8B8UA70
uniprot id: A0A8B8UAN1
names: Subcellular Location Annotation
messages: Membrane

419612:NKX3-1
gene id: 419612:NKX3-1
uniprot id: A0A8B8SAH7
names: Subcellular Location Annotation
messages: Nucleus

419612:ARRDC3
gene id: 419612:ARRDC3
uniprot id: A0A8B6YM93
uniprot id: A0A8B8SR59
names: Similarity
messages: Belongs to the arrestin family.

419612:CALR
gene id: 419612:CALR
uniprot id: A0A8B6YB36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

419612:RBX1
gene id: 419612:RBX1
uniprot id: A0A8B6YAK0
names: Similarity
messages: Belongs to the RING-box family.

419612:TFRC
gene id: 419612:TFRC
uniprot id: A0A8B7KCM3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

419612:HEPHL1
gene id: 419612:HEPHL1
uniprot id: A0A8B6YQD7
uniprot id: A0A8B6YS97
names: Similarity
messages: Belongs to the multicopper oxidase family.

419612:EHD4
gene id: 419612:EHD4
uniprot id: A0A8B6Y9Z4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

419612:S1PR2
gene id: 419612:S1PR2
uniprot id: T0NQ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:PDE8A
gene id: 419612:PDE8A
uniprot id: A0A8B8S3V8
uniprot id: A0A8B8S3W5
uniprot id: A0A8B8S5T2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

419612:ATP13A4
gene id: 419612:ATP13A4
uniprot id: A0A8B8T6E5
uniprot id: A0A8B8T735
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

419612:SCN5A
gene id: 419612:SCN5A
uniprot id: A0A8B8RAS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

419612:SSX2IP
gene id: 419612:SSX2IP
uniprot id: A0A8B8U7L4
uniprot id: A0A8B8U7L8
uniprot id: A0A8B8U8F6
uniprot id: A0A8B8U8G0
uniprot id: A0A8B8U8L9
uniprot id: A0A8B8U8M4
uniprot id: A0A8B8U8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

419612:MRPS10
gene id: 419612:MRPS10
uniprot id: A0A8B6YKP4
uniprot id: A0A8B7KDT2
uniprot id: A0A8B8RM17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

419612:LOC102516228
gene id: 419612:LOC102516228
uniprot id: A0A8B7KFA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:STEAP2
gene id: 419612:STEAP2
uniprot id: A0A8B8TCI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

419612:CTPS1
gene id: 419612:CTPS1
uniprot id: A0A8B8U6N4
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

419612:LOC102517428
gene id: 419612:LOC102517428
uniprot id: A0A8B6YM40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CDC20
gene id: 419612:CDC20
uniprot id: A0A8B8U6W8
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

419612:FMO5
gene id: 419612:FMO5
uniprot id: S9XQV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

419612:LOC102520738
gene id: 419612:LOC102520738
uniprot id: A0A8B6YAB8
uniprot id: A0A8B8THE9
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

419612:DKC1
gene id: 419612:DKC1
uniprot id: A0A8B8SNQ3
uniprot id: A0A8B8SPN0
uniprot id: A0A8B8SPY7
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

419612:LOC102514673
gene id: 419612:LOC102514673
uniprot id: A0A8B8SU06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

419612:NEXMIF
gene id: 419612:NEXMIF
uniprot id: S9XD31
names: Subcellular Location Annotation
messages: Nucleus

419612:PUS7L
gene id: 419612:PUS7L
uniprot id: A0A8B6YP53
uniprot id: A0A8B8U3K2
uniprot id: A0A8B8U3L0
uniprot id: A0A8B8U496
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

419612:FREM2
gene id: 419612:FREM2
uniprot id: A0A8B8UC36
names: Similarity
messages: Belongs to the FRAS1 family.

419612:SLC10A1
gene id: 419612:SLC10A1
uniprot id: A0A8B6YKZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

419612:STX17
gene id: 419612:STX17
uniprot id: A0A8B8SVI5
names: Similarity
messages: Belongs to the syntaxin family.

419612:LOC102519025
gene id: 419612:LOC102519025
uniprot id: A0A8B7KDK0
names: Similarity
messages: Belongs to the eIF-1A family.

419612:RPS3
gene id: 419612:RPS3
uniprot id: S9XG44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: spindle

419612:SERP2
gene id: 419612:SERP2
uniprot id: A0A8B8UBN5
uniprot id: A0A8B8UBN6
uniprot id: A0A8B8UD13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

419612:LIN7B
gene id: 419612:LIN7B
uniprot id: A0A8B8TGU8
uniprot id: A0A8B8TGV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

419612:CLPTM1L
gene id: 419612:CLPTM1L
uniprot id: A0A8B6Y4S9
uniprot id: A0A8B8S6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

419612:PACS1
gene id: 419612:PACS1
uniprot id: A0A8B8TU01
uniprot id: A0A8B8TU02
uniprot id: A0A8B8TU11
uniprot id: A0A8B8TV72
names: Similarity
messages: Belongs to the PACS family.

419612:RPA4
gene id: 419612:RPA4
uniprot id: S9W8E4
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

419612:CRHR2
gene id: 419612:CRHR2
uniprot id: A0A8B8TBN3
uniprot id: A0A8B8TC02
uniprot id: A0A8B8TCW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

419612:LOC102512283
gene id: 419612:LOC102512283
uniprot id: A0A8B8UID2
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

419612:CRYL1
gene id: 419612:CRYL1
uniprot id: A0A8B7K4Q6
uniprot id: A0A8B8UCT3
uniprot id: A0A8B8UCT6
uniprot id: A0A8B8UE48
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

419612:ALDOC
gene id: 419612:ALDOC
uniprot id: A0A8B6YJL9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

419612:FN1
gene id: 419612:FN1
uniprot id: A0A8B6YEY9
uniprot id: A0A8B6YEZ5
uniprot id: A0A8B6YEZ9
uniprot id: A0A8B6YFA1
uniprot id: A0A8B6YFA6
uniprot id: A0A8B6YG83
uniprot id: A0A8B6YJ15
uniprot id: A0A8B6YJ22
uniprot id: A0A8B7K9J8
uniprot id: A0A8B7K9V3
uniprot id: A0A8B7KA75
uniprot id: A0A8B7KBK1
uniprot id: A0A8B8T120
names: Function
messages: Secreted by contracting muscle, induces liver autophagy, a degradative pathway for nutrient mobilization and damage removal, and systemic insulin sensitization via hepatic ITGA5:ITGB1 integrin receptor signaling.

419612:GALR3
gene id: 419612:GALR3
uniprot id: A0A8B8U0W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

419612:CFAP97D2
gene id: 419612:CFAP97D2
uniprot id: A0A8B7K506
uniprot id: A0A8B8UCZ0
uniprot id: A0A8B8UDR8
uniprot id: A0A8B8UEA3
names: Similarity
messages: Belongs to the CFAP97 family.

419612:TUBA1A
gene id: 419612:TUBA1A
uniprot id: A0A8B8U3B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

419612:MAP7D2
gene id: 419612:MAP7D2
uniprot id: A0A8B7KFY9
uniprot id: A0A8B8SJP8
uniprot id: A0A8B8SJQ3
uniprot id: A0A8B8SJQ7
uniprot id: A0A8B8SJR4
uniprot id: A0A8B8SKT7
uniprot id: A0A8B8SKV0
uniprot id: A0A8B8SL60
uniprot id: A0A8B8SM35
uniprot id: A0A8B8SM40
names: Similarity
messages: Belongs to the MAP7 family.

419612:TEAD3
gene id: 419612:TEAD3
uniprot id: A0A8B8RLI5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

419612:SIX4
gene id: 419612:SIX4
uniprot id: A0A8B8T702
uniprot id: A0A8B8T7L2
names: Subcellular Location Annotation
messages: Nucleus

419612:NIM1K
gene id: 419612:NIM1K
uniprot id: S9WBH3
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:LOC102510405
gene id: 419612:LOC102510405
uniprot id: A0A8B8TI21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

419612:PIGP
gene id: 419612:PIGP
uniprot id: A0A8B8S1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

419612:MAST3
gene id: 419612:MAST3
uniprot id: A0A8B6Y892
uniprot id: A0A8B7K379
uniprot id: A0A8B7K3C3
uniprot id: A0A8B7K3R8
uniprot id: A0A8B7K5R0
uniprot id: A0A8B8RT52
uniprot id: A0A8B8RT55
uniprot id: A0A8B8RT56
uniprot id: A0A8B8RU33
uniprot id: A0A8B8RU39
uniprot id: A0A8B8RUS3
uniprot id: A0A8B8RV29
uniprot id: A0A8B8RV33
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

419612:LOC102511022
gene id: 419612:LOC102511022
uniprot id: A0A8B8U6E9
names: Similarity
messages: Belongs to the intermediate filament family.

419612:DGKQ
gene id: 419612:DGKQ
uniprot id: A0A8B8TZF9
uniprot id: A0A8B8TZH6
uniprot id: A0A8B8TZI7
uniprot id: A0A8B8TZJ7
uniprot id: A0A8B8TZK9
uniprot id: A0A8B8TZT5
uniprot id: A0A8B8U0F6
uniprot id: A0A8B8U0J7
uniprot id: A0A8B8U0T3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

419612:MITF
gene id: 419612:MITF
uniprot id: A0A8B6YH48
uniprot id: A0A8B6YHF3
uniprot id: A0A8B6YID2
uniprot id: A0A8B6YL36
uniprot id: A0A8B7KBE4
uniprot id: A0A8B7KBZ2
uniprot id: A0A8B8R7L7
uniprot id: A0A8B8R7M1
uniprot id: A0A8B8R7M7
uniprot id: A0A8B8R7S1
uniprot id: A0A8B8R9R8
uniprot id: A0A8B8RAG6
uniprot id: A0A8B8RAG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

419612:SLC16A4
gene id: 419612:SLC16A4
uniprot id: A0A8B6YP94
names: Subcellular Location Annotation
messages: Membrane

419612:RXFP1
gene id: 419612:RXFP1
uniprot id: A0A8B7K9T5
uniprot id: A0A8B8RV88
uniprot id: A0A8B8RWT5
uniprot id: A0A8B8RX45
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:PKIG
gene id: 419612:PKIG
uniprot id: A0A8B8RGM3
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

419612:INHBA
gene id: 419612:INHBA
uniprot id: A0A8B6YFC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

419612:CPN1
gene id: 419612:CPN1
uniprot id: A0A8B6YHV2
uniprot id: A0A8B8TXG4
names: Similarity
messages: Belongs to the peptidase M14 family.

419612:ASRGL1
gene id: 419612:ASRGL1
uniprot id: A0A8B6Y987
uniprot id: A0A8B8TT85
names: Similarity
names: Subunit
messages: Belongs to the Ntn-hydrolase family.
messages: Heterodimer of an alpha and beta chain produced by autocleavage. This heterodimer may then dimerize in turn, giving rise to a heterotetramer.

419612:TCP11L1
gene id: 419612:TCP11L1
uniprot id: A0A8B8TPX3
uniprot id: A0A8B8TPY6
uniprot id: A0A8B8TR26
names: Similarity
messages: Belongs to the TCP11 family.

419612:MCM10
gene id: 419612:MCM10
uniprot id: A0A8B7KCE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

419612:CCNJ
gene id: 419612:CCNJ
uniprot id: A0A8B8TXR7
uniprot id: A0A8B8TXR8
uniprot id: A0A8B8TXR9
uniprot id: A0A8B8TXS4
uniprot id: A0A8B8TZ36
uniprot id: A0A8B8TZ41
names: Similarity
messages: Belongs to the cyclin family.

419612:MCM7
gene id: 419612:MCM7
uniprot id: A0A8B7K7M7
uniprot id: A0A8B8REV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

419612:LOC102504735
gene id: 419612:LOC102504735
uniprot id: A0A8B6YAP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:KEG61 p02
gene id: 419612:KEG61_p02
uniprot id: A6YAS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

419612:LOC102514326
gene id: 419612:LOC102514326
uniprot id: A0A8B6YIQ8
uniprot id: A0A8B7KDK7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

419612:TMEM115
gene id: 419612:TMEM115
uniprot id: A0A8B6Y5V0
names: Subcellular Location Annotation
messages: Membrane

419612:IL1R1
gene id: 419612:IL1R1
uniprot id: A0A8B8S610
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

419612:JUNB
gene id: 419612:JUNB
uniprot id: A0A8B8RVI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

419612:LOC102520697
gene id: 419612:LOC102520697
uniprot id: A0A8B8THV9
names: Subcellular Location Annotation
messages: Nucleus

419612:HEPH
gene id: 419612:HEPH
uniprot id: A0A8B8SNT9
names: Similarity
messages: Belongs to the multicopper oxidase family.

419612:CMKLR1
gene id: 419612:CMKLR1
uniprot id: A0A8B7K465
uniprot id: S9XGR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

419612:CYFIP1
gene id: 419612:CYFIP1
uniprot id: A0A8B8SZ76
names: Similarity
messages: Belongs to the CYFIP family.

419612:SPSB2
gene id: 419612:SPSB2
uniprot id: A0A8B8SGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

419612:EZH2
gene id: 419612:EZH2
uniprot id: A0A8B8TA80
uniprot id: A0A8B8TA84
uniprot id: A0A8B8TA85
uniprot id: A0A8B8TAC3
uniprot id: A0A8B8TAC7
uniprot id: A0A8B8TAN1
uniprot id: A0A8B8TAN6
uniprot id: A0A8B8TBB5
uniprot id: A0A8B8TBC1
names: Subcellular Location Annotation
messages: Nucleus

419612:MLH3
gene id: 419612:MLH3
uniprot id: A0A8B6YGE3
uniprot id: A0A8B8T7P8
uniprot id: A0A8B8T7Q4
uniprot id: A0A8B8T891
uniprot id: A0A8B8T896
uniprot id: A0A8B8T8M5
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

419612:LOC102521033
gene id: 419612:LOC102521033
uniprot id: A0A8B6Y670
names: Similarity
messages: Belongs to the PRORSD1 family.

419612:SH3BP5
gene id: 419612:SH3BP5
uniprot id: A0A8B8TT11
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

419612:CRY2
gene id: 419612:CRY2
uniprot id: A0A8B8TQ80
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

419612:LOC102513522
gene id: 419612:LOC102513522
uniprot id: A0A8B6Y6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SLC6A14
gene id: 419612:SLC6A14
uniprot id: A0A8B6YNK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

419612:CHRNG
gene id: 419612:CHRNG
uniprot id: A0A8B6YLC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:MOGAT2
gene id: 419612:MOGAT2
uniprot id: A0A8B8TTP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:RABGGTA
gene id: 419612:RABGGTA
uniprot id: A0A8B8T6K6
uniprot id: A0A8B8T6S0
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

419612:LOC102505200
gene id: 419612:LOC102505200
uniprot id: S9XZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MMP15
gene id: 419612:MMP15
uniprot id: A0A8B8TJA1
uniprot id: A0A8B8TJB6
uniprot id: A0A8B8TJH7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

419612:ATP5MC2
gene id: 419612:ATP5MC2
uniprot id: A0A8B7K8Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

419612:SLC25A36
gene id: 419612:SLC25A36
uniprot id: A0A8B8TM35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:ARMC9
gene id: 419612:ARMC9
uniprot id: A0A8B6YEH6
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with TOGARAM1, CCDC66, CEP104, CSPP1 and CEP290.
messages: centriole
messages: cilium
messages: cilium basal body

419612:TMEM120A
gene id: 419612:TMEM120A
uniprot id: A0A8B6YDA7
uniprot id: A0A8B8RBX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

419612:SLC6A7
gene id: 419612:SLC6A7
uniprot id: A0A8B8SSV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

419612:EVC
gene id: 419612:EVC
uniprot id: A0A8B8U554
uniprot id: A0A8B8U558
uniprot id: A0A8B8U562
uniprot id: A0A8B8U567
uniprot id: A0A8B8U570
uniprot id: A0A8B8U5Y1
uniprot id: A0A8B8U605
uniprot id: A0A8B8U609
uniprot id: A0A8B8U623
uniprot id: A0A8B8U633
uniprot id: A0A8B8U695
uniprot id: A0A8B8U6B0
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

419612:DCTPP1
gene id: 419612:DCTPP1
uniprot id: A0A8B6YDT2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homotetramer.
messages: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
messages: cytosol

419612:ANP32E
gene id: 419612:ANP32E
uniprot id: A0A8B6YH58
uniprot id: A0A8B8RRA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

419612:KEG61 p09
gene id: 419612:KEG61_p09
uniprot id: A6YAR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion membrane

419612:ACTR5
gene id: 419612:ACTR5
uniprot id: A0A8B8RK23
names: Similarity
messages: Belongs to the actin family.

419612:VLDLR
gene id: 419612:VLDLR
uniprot id: A0A8B8SU63
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102512064
gene id: 419612:LOC102512064
uniprot id: A0A8B6YKK3
names: Similarity
messages: Belongs to the CLCR family.

419612:COPB1
gene id: 419612:COPB1
uniprot id: A0A8B6YQG9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Endoplasmic reticulum-Golgi intermediate compartment
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

419612:LOC102504974
gene id: 419612:LOC102504974
uniprot id: A0A8B8RW94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

419612:NOVA2
gene id: 419612:NOVA2
uniprot id: A0A8B8THC6
uniprot id: A0A8B8THF2
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

419612:LOC102505705
gene id: 419612:LOC102505705
uniprot id: A0A8B7K771
uniprot id: S9YA11
names: Similarity
messages: Belongs to the MHC class II family.

419612:MYD88
gene id: 419612:MYD88
uniprot id: A0A8B8RAX8
uniprot id: A0A8B8RAY6
uniprot id: A0A8B8RD14
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm
messages: Homodimer. Also forms heterodimers with TIRAP. Binds to TLR2, TLR4, IRAK1, IRAK2 and IRAK4 via their respective TIR domains.

419612:ARHGEF1
gene id: 419612:ARHGEF1
uniprot id: A0A8B8THS4
uniprot id: A0A8B8THS9
uniprot id: A0A8B8THW1
uniprot id: A0A8B8TJ25
names: Subcellular Location Annotation
messages: Membrane

419612:LOC116661879
gene id: 419612:LOC116661879
uniprot id: A0A8B8SK34
names: Similarity
messages: Belongs to the histone H2B family.

419612:PIGW
gene id: 419612:PIGW
uniprot id: A0A8B6Y6B8
uniprot id: A0A8B8UIL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

419612:ARPC2
gene id: 419612:ARPC2
uniprot id: A0A8B8T215
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with SHANK3; the interaction probably mediates the association of SHANK3 with the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton
messages: synaptosome

419612:TTC39B
gene id: 419612:TTC39B
uniprot id: A0A8B7KCF8
uniprot id: A0A8B8STY2
uniprot id: A0A8B8SUF1
names: Similarity
messages: Belongs to the TTC39 family.

419612:ISOC1
gene id: 419612:ISOC1
uniprot id: A0A8B8SRZ5
names: Similarity
messages: Belongs to the isochorismatase family.

419612:LOC102508859
gene id: 419612:LOC102508859
uniprot id: A0A8B6YFR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:MKNK1
gene id: 419612:MKNK1
uniprot id: A0A8B7K5U2
uniprot id: A0A8B8U657
uniprot id: A0A8B8U725
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:NDUFB1
gene id: 419612:NDUFB1
uniprot id: A0A8B8T8N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

419612:FAM161A
gene id: 419612:FAM161A
uniprot id: A0A8B6YLJ7
uniprot id: A0A8B7KGG6
uniprot id: A0A8B8UG13
uniprot id: A0A8B8UGR5
names: Similarity
messages: Belongs to the FAM161 family.

419612:MAN2B2
gene id: 419612:MAN2B2
uniprot id: A0A8B8UBG4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

419612:RFNG
gene id: 419612:RFNG
uniprot id: A0A8B8R2Y2
uniprot id: A0A8B8R2Z5
uniprot id: A0A8B8R5A8
uniprot id: A0A8B8R5P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:LOC116666689
gene id: 419612:LOC116666689
uniprot id: A0A8B8TWW0
names: Similarity
messages: Belongs to the GOLGA6 family.

419612:DNMT3B
gene id: 419612:DNMT3B
uniprot id: A0A8B8RJ72
uniprot id: A0A8B8RJ78
uniprot id: A0A8B8RJG4
uniprot id: A0A8B8RLG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

419612:USP48
gene id: 419612:USP48
uniprot id: A0A8B8U9K2
uniprot id: A0A8B8U9K8
uniprot id: A0A8B8UAC8
uniprot id: A0A8B8UAH3
uniprot id: A0A8B8UAT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

419612:KCNMB2
gene id: 419612:KCNMB2
uniprot id: A0A8B6YEI2
uniprot id: A0A8B8TDG0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

419612:IL4R
gene id: 419612:IL4R
uniprot id: A0A8B7KB75
uniprot id: A0A8B8REV1
uniprot id: S9Y6E3
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

419612:PPP1R14D
gene id: 419612:PPP1R14D
uniprot id: A0A8B6Y8E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

419612:LOC102524556
gene id: 419612:LOC102524556
uniprot id: A0A8B6YKX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:AGTPBP1
gene id: 419612:AGTPBP1
uniprot id: A0A8B8SUB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

419612:SLC5A8
gene id: 419612:SLC5A8
uniprot id: A0A8B6YPQ0
uniprot id: A0A8B8U5I0
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

419612:WEE1
gene id: 419612:WEE1
uniprot id: A0A8B8TRN8
uniprot id: A0A8B8TSI3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

419612:DYRK1A
gene id: 419612:DYRK1A
uniprot id: A0A8B8RZL9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

419612:RGS5
gene id: 419612:RGS5
uniprot id: A0A8B8RR87
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

419612:SLC39A12
gene id: 419612:SLC39A12
uniprot id: A0A8B8SH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

419612:LOC102517336
gene id: 419612:LOC102517336
uniprot id: A0A8B7K4M5
names: Caution
names: Cofactor
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:ATM
gene id: 419612:ATM
uniprot id: A0A8B8SDT0
uniprot id: A0A8B8SGC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Cytoplasmic vesicle
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9, UBQLN4 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response. Phosphorylates ERCC6 which is essential for its chromatin remodeling activity at DNA double-strand breaks.

419612:ANTKMT
gene id: 419612:ANTKMT
uniprot id: A0A8B6Y5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

419612:LPCAT4
gene id: 419612:LPCAT4
uniprot id: A0A8B8T639
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

419612:CIT
gene id: 419612:CIT
uniprot id: A0A8B6YP41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Plays a role in cytokinesis. Displays serine/threonine protein kinase activity.

419612:PAM16
gene id: 419612:PAM16
uniprot id: A0A8B6YBP0
names: Similarity
messages: Belongs to the TIM16/PAM16 family.

419612:MRPL52
gene id: 419612:MRPL52
uniprot id: A0A8B6YBE0
uniprot id: A0A8B7K3V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

419612:LOC102506455
gene id: 419612:LOC102506455
uniprot id: S9X902
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:DCTN2
gene id: 419612:DCTN2
uniprot id: A0A8B8U3D1
uniprot id: A0A8B8U3D2
uniprot id: A0A8B8U3D6
uniprot id: A0A8B8U3D7
uniprot id: A0A8B8U415
uniprot id: A0A8B8U420
uniprot id: A0A8B8U4C4
uniprot id: A0A8B8U4C8
uniprot id: A0A8B8U4J8
uniprot id: A0A8B8U4K3
names: Similarity
messages: Belongs to the dynactin subunit 2 family.

419612:PHKA1
gene id: 419612:PHKA1
uniprot id: A0A8B6YNS2
uniprot id: A0A8B6YP06
uniprot id: A0A8B6YSE2
uniprot id: A0A8B7KG53
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

419612:CD5
gene id: 419612:CD5
uniprot id: A0A8B8TT17
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:FAM171A2
gene id: 419612:FAM171A2
uniprot id: A0A8B8R7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

419612:RELT
gene id: 419612:RELT
uniprot id: A0A8B8TSF2
names: Caution
names: Similarity
messages: Belongs to the RELT family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102511301
gene id: 419612:LOC102511301
uniprot id: A0A8B8RMY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SGTB
gene id: 419612:SGTB
uniprot id: A0A8B8SGX3
uniprot id: A0A8B8SH21
names: Similarity
messages: Belongs to the SGT family.

419612:LOC102505892
gene id: 419612:LOC102505892
uniprot id: S9Y2B8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

419612:ME3
gene id: 419612:ME3
uniprot id: A0A8B6YJX3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

419612:E2F3
gene id: 419612:E2F3
uniprot id: A0A8B8RKJ6
uniprot id: A0A8B8RKV0
uniprot id: A0A8B8RMB5
uniprot id: A0A8B8RMS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

419612:LOC116661885
gene id: 419612:LOC116661885
uniprot id: A0A8B8SLI6
names: Subcellular Location Annotation
messages: Membrane

419612:PKD2L1
gene id: 419612:PKD2L1
uniprot id: A0A8B7K8S1
uniprot id: A0A8B7K8T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane
messages: cilium membrane

419612:HOXC9
gene id: 419612:HOXC9
uniprot id: A0A8B8U429
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

419612:RCE1
gene id: 419612:RCE1
uniprot id: A0A8B8TU64
uniprot id: A0A8B8TU66
uniprot id: A0A8B8TU67
uniprot id: A0A8B8TV98
uniprot id: A0A8B8TVE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:SERF1A
gene id: 419612:SERF1A
uniprot id: A0A8B6YJU6
names: Similarity
messages: Belongs to the SERF family.

419612:LOC102524252
gene id: 419612:LOC102524252
uniprot id: A0A8B7K7S0
uniprot id: A0A8B8TJQ2
uniprot id: A0A8B8TJR4
uniprot id: A0A8B8TJY8
uniprot id: A0A8B8TKY1
names: Subcellular Location Annotation
messages: cilium axoneme

419612:PSMB3
gene id: 419612:PSMB3
uniprot id: A0A8B6Y857
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

419612:CSAD
gene id: 419612:CSAD
uniprot id: A0A8B7K8R9
uniprot id: A0A8B8U2M5
uniprot id: A0A8B8U3M0
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

419612:LOC102523900
gene id: 419612:LOC102523900
uniprot id: S9WAV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:HSPG2
gene id: 419612:HSPG2
uniprot id: A0A8B8U9L7
uniprot id: A0A8B8U9L8
uniprot id: A0A8B8U9M5
uniprot id: A0A8B8UAD9
uniprot id: A0A8B8UAE5
uniprot id: A0A8B8UAI8
uniprot id: A0A8B8UAV0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

419612:LAMA1
gene id: 419612:LAMA1
uniprot id: A0A8B8RZL5
uniprot id: A0A8B8RZM3
uniprot id: A0A8B8S0Y5
uniprot id: A0A8B8S153
uniprot id: A0A8B8S182
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

419612:TAAR2
gene id: 419612:TAAR2
uniprot id: A0A8B6YPR5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:CDC42BPA
gene id: 419612:CDC42BPA
uniprot id: A0A8B6YIH8
uniprot id: A0A8B6YJT5
uniprot id: A0A8B7KC47
uniprot id: A0A8B7KC57
uniprot id: A0A8B7KCG0
uniprot id: A0A8B7KD66
uniprot id: A0A8B7KD71
uniprot id: A0A8B7KE84
uniprot id: A0A8B8RWY8
uniprot id: A0A8B8RWZ0
uniprot id: A0A8B8RY96
uniprot id: A0A8B8RYD8
uniprot id: A0A8B8RYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

419612:PTH1R
gene id: 419612:PTH1R
uniprot id: A0A8B8R986
uniprot id: A0A8B8RC18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

419612:KRT36
gene id: 419612:KRT36
uniprot id: A0A8B8UHH7
uniprot id: A0A8B8UIT7
names: Similarity
messages: Belongs to the intermediate filament family.

419612:ABCA3
gene id: 419612:ABCA3
uniprot id: A0A8B8RDV5
uniprot id: A0A8B8RG84
names: Subcellular Location Annotation
messages: Membrane

419612:ELAC2
gene id: 419612:ELAC2
uniprot id: A0A8B8UJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Z family.
messages: mitochondrion nucleoid

419612:PIAS4
gene id: 419612:PIAS4
uniprot id: A0A8B8RV30
uniprot id: A0A8B8RW78
names: Similarity
messages: Belongs to the PIAS family.

419612:NDUFV3
gene id: 419612:NDUFV3
uniprot id: A0A8B8R8J0
uniprot id: A0A8B8R8P5
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

419612:RAD52
gene id: 419612:RAD52
uniprot id: A0A8B8SER2
uniprot id: A0A8B8SFY0
uniprot id: A0A8B8SG00
uniprot id: A0A8B8SHB7
names: Similarity
messages: Belongs to the RAD52 family.

419612:DYNLRB1
gene id: 419612:DYNLRB1
uniprot id: A0A8B6YPL5
uniprot id: A0A8B8RLQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

419612:LOC116664132
gene id: 419612:LOC116664132
uniprot id: A0A8B8T5A9
names: Subcellular Location Annotation
messages: Nucleus

419612:TCP11L2
gene id: 419612:TCP11L2
uniprot id: A0A8B8U3Z8
uniprot id: A0A8B8U4Q4
uniprot id: A0A8B8U566
names: Similarity
messages: Belongs to the TCP11 family.

419612:LOC102514805
gene id: 419612:LOC102514805
uniprot id: A0A8B8RCI1
uniprot id: A0A8B8REJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

419612:ZNF660
gene id: 419612:ZNF660
uniprot id: A0A8B8RAF9
uniprot id: A0A8B8RCJ5
names: Subcellular Location Annotation
messages: Nucleus

419612:MIEF2
gene id: 419612:MIEF2
uniprot id: A0A8B7K482
uniprot id: A0A8B8UK13
uniprot id: A0A8B8UL08
uniprot id: S9XHY7
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

419612:SAP130
gene id: 419612:SAP130
uniprot id: A0A8B8SYL0
uniprot id: A0A8B8SYM9
uniprot id: A0A8B8SYN4
uniprot id: A0A8B8SZ29
uniprot id: A0A8B8SZ33
uniprot id: A0A8B8SZ47
uniprot id: A0A8B8SZ51
uniprot id: A0A8B8SZN7
uniprot id: A0A8B8SZP2
uniprot id: A0A8B8SZP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

419612:PPP1R1B
gene id: 419612:PPP1R1B
uniprot id: A0A8B8R743
uniprot id: A0A8B8R9X7
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

419612:MED8
gene id: 419612:MED8
uniprot id: A0A8B8U5T2
uniprot id: A0A8B8U5T4
uniprot id: A0A8B8U6P7
uniprot id: A0A8B8U6Q1
uniprot id: A0A8B8U6Q4
uniprot id: A0A8B8U6X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

419612:ZNF280D
gene id: 419612:ZNF280D
uniprot id: A0A8B7K7W5
uniprot id: A0A8B7K7Z2
uniprot id: A0A8B7K8G8
uniprot id: A0A8B8T408
uniprot id: A0A8B8T4S7
uniprot id: A0A8B8T4T9
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

419612:TEX13D
gene id: 419612:TEX13D
uniprot id: A0A8B8SK63
names: Similarity
messages: Belongs to the TEX13 family.

419612:MAP2K4
gene id: 419612:MAP2K4
uniprot id: A0A8B8UJJ0
uniprot id: A0A8B8UJX4
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:DYNC1LI2
gene id: 419612:DYNC1LI2
uniprot id: A0A8B8TJD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

419612:ADGRG3
gene id: 419612:ADGRG3
uniprot id: A0A8B7K711
uniprot id: A0A8B8TJ85
uniprot id: A0A8B8TJF4
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102512973
gene id: 419612:LOC102512973
uniprot id: A0A8B6Y8W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TSPAN4
gene id: 419612:TSPAN4
uniprot id: A0A8B8TV44
uniprot id: A0A8B8TV45
uniprot id: A0A8B8TV46
uniprot id: A0A8B8TW65
uniprot id: A0A8B8TWE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:PSMD8
gene id: 419612:PSMD8
uniprot id: A0A8B6YBH8
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

419612:CREG2
gene id: 419612:CREG2
uniprot id: A0A8B8S565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

419612:POLB
gene id: 419612:POLB
uniprot id: A0A8B8S4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

419612:GCK
gene id: 419612:GCK
uniprot id: A0A8B8TD80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

419612:AR
gene id: 419612:AR
uniprot id: A0A8B8SLK4
names: Similarity
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.

419612:HOXB13
gene id: 419612:HOXB13
uniprot id: A0A8B6Y7S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

419612:CDK5RAP3
gene id: 419612:CDK5RAP3
uniprot id: A0A8B6YBV4
names: Similarity
messages: Belongs to the CDK5RAP3 family.

419612:RAMAC
gene id: 419612:RAMAC
uniprot id: S9XTL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAM family.
messages: Nucleus

419612:TCEA3
gene id: 419612:TCEA3
uniprot id: A0A8B8U9S7
uniprot id: A0A8B8UAP9
uniprot id: A0A8B8UB11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

419612:MUC2
gene id: 419612:MUC2
uniprot id: A0A8B8TVT4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:DCTD
gene id: 419612:DCTD
uniprot id: A0A8B8S2M3
uniprot id: A0A8B8S3Z4
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

419612:CCDC85B
gene id: 419612:CCDC85B
uniprot id: A0A8B8TTZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

419612:PLSCR3
gene id: 419612:PLSCR3
uniprot id: A0A8B7K4A3
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

419612:CPSF2
gene id: 419612:CPSF2
uniprot id: A0A8B6YEV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

419612:ITGA7
gene id: 419612:ITGA7
uniprot id: A0A8B8U343
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

419612:XPO7
gene id: 419612:XPO7
uniprot id: A0A8B8S9L1
uniprot id: A0A8B8SBY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

419612:PRKCG
gene id: 419612:PRKCG
uniprot id: A0A8B8TMX0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane

419612:MPZ
gene id: 419612:MPZ
uniprot id: A0A8B6Y9V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the myelin P0 protein family.
messages: Cell membrane
messages: Homodimer and homotetramer.
messages: Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
messages: Membrane

419612:SLC39A8
gene id: 419612:SLC39A8
uniprot id: A0A8B8RF97
names: Subcellular Location Annotation
messages: Membrane

419612:ANKS4B
gene id: 419612:ANKS4B
uniprot id: S9XFN8
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

419612:NUDT2
gene id: 419612:NUDT2
uniprot id: S9WW66
names: Similarity
messages: Belongs to the Nudix hydrolase family.

419612:OPN4
gene id: 419612:OPN4
uniprot id: A0A8B8TYZ2
uniprot id: A0A8B8TYZ6
uniprot id: A0A8B8U0A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

419612:DAO
gene id: 419612:DAO
uniprot id: A0A8B7K420
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

419612:TMCO1
gene id: 419612:TMCO1
uniprot id: A0A8B6Y903
uniprot id: A0A8B8RP51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Homodimer and homotetramer. Homodimer under resting conditions; forms homotetramers following and ER calcium overload.
messages: Membrane

419612:ZC3H12D
gene id: 419612:ZC3H12D
uniprot id: A0A8B7KCJ7
uniprot id: A0A8B8TFK5
names: Similarity
messages: Belongs to the ZC3H12 family.

419612:PIK3C2A
gene id: 419612:PIK3C2A
uniprot id: A0A8B7KGP9
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

419612:GLUD1
gene id: 419612:GLUD1
uniprot id: A0A8B8TZ30
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

419612:LOC102512522
gene id: 419612:LOC102512522
uniprot id: A0A8B8RMX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102520754
gene id: 419612:LOC102520754
uniprot id: A0A8B6YG92
names: Similarity
messages: Belongs to the PPDPF family.

419612:YTHDF1
gene id: 419612:YTHDF1
uniprot id: A0A8B8RHK7
uniprot id: A0A8B8RHL1
uniprot id: A0A8B8RHT6
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

419612:FOXE1
gene id: 419612:FOXE1
uniprot id: A0A8B8SV18
names: Subcellular Location Annotation
messages: Nucleus

419612:FAM114A1
gene id: 419612:FAM114A1
uniprot id: A0A8B8UBA8
uniprot id: A0A8B8UC14
uniprot id: A0A8B8UCL4
names: Similarity
messages: Belongs to the FAM114 family.

419612:IL1RL1
gene id: 419612:IL1RL1
uniprot id: A0A8B8S5I5
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

419612:SRRT
gene id: 419612:SRRT
uniprot id: A0A8B7K7C3
uniprot id: A0A8B7K7F0
uniprot id: A0A8B8RC37
uniprot id: A0A8B8RC40
uniprot id: A0A8B8RE75
uniprot id: A0A8B8REN7
uniprot id: S9X8N9
names: Similarity
messages: Belongs to the ARS2 family.

419612:SCAND1
gene id: 419612:SCAND1
uniprot id: A0A8B7KCK1
names: Subcellular Location Annotation
messages: Nucleus

419612:ADAM28
gene id: 419612:ADAM28
uniprot id: A0A8B8S928
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:TGS1
gene id: 419612:TGS1
uniprot id: A0A8B6YL17
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

419612:OXR1
gene id: 419612:OXR1
uniprot id: A0A8B7KCV1
uniprot id: A0A8B7KD45
uniprot id: A0A8B7KDZ8
uniprot id: A0A8B8S0S2
uniprot id: A0A8B8S0T5
uniprot id: A0A8B8S248
uniprot id: A0A8B8S2D9
uniprot id: A0A8B8S2E4
names: Similarity
messages: Belongs to the OXR1 family.

419612:POLR1E
gene id: 419612:POLR1E
uniprot id: A0A8B7KBW5
uniprot id: A0A8B8SWE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

419612:FAM219A
gene id: 419612:FAM219A
uniprot id: A0A8B8STL1
uniprot id: A0A8B8STQ3
uniprot id: A0A8B8SU34
uniprot id: A0A8B8SUH9
uniprot id: A0A8B8SV60
uniprot id: A0A8B8SV64
names: Similarity
messages: Belongs to the FAM219 family.

419612:CFC1
gene id: 419612:CFC1
uniprot id: A0A8B8SZ53
uniprot id: A0A8B8SZR5
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:ARL2
gene id: 419612:ARL2
uniprot id: A0A8B6YAU8
uniprot id: A0A8B8TUX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

419612:PKDREJ
gene id: 419612:PKDREJ
uniprot id: A0A8B8U1P4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:SMARCA2
gene id: 419612:SMARCA2
uniprot id: A0A8B8SUM6
uniprot id: A0A8B8SV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

419612:LOC102513138
gene id: 419612:LOC102513138
uniprot id: S9XT51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the S-100 family.
messages: Facilitates the differentiation and the cornification of keratinocytes.
messages: Homodimer; disulfide-linked.

419612:LOC102516142
gene id: 419612:LOC102516142
uniprot id: A0A8B8RD31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

419612:LOC102519079
gene id: 419612:LOC102519079
uniprot id: A0A8B6YDZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PNPLA1
gene id: 419612:PNPLA1
uniprot id: A0A8B6YPP3
uniprot id: A0A8B8RNE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MDM1
gene id: 419612:MDM1
uniprot id: A0A8B6YJW2
uniprot id: A0A8B8U4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM1 family.
messages: Nucleus
messages: centriole

419612:HOOK2
gene id: 419612:HOOK2
uniprot id: A0A8B8RVI7
uniprot id: A0A8B8RVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

419612:LOC102515882
gene id: 419612:LOC102515882
uniprot id: A0A8B8RFD7
uniprot id: A0A8B8RFK0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:TMEM151B
gene id: 419612:TMEM151B
uniprot id: A0A8B8RMB1
uniprot id: A0A8B8RML8
uniprot id: A0A8B8RP13
uniprot id: A0A8B8RPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

419612:ETV3
gene id: 419612:ETV3
uniprot id: A0A8B8RRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:SENP8
gene id: 419612:SENP8
uniprot id: A0A8B8S4A6
names: Similarity
messages: Belongs to the peptidase C48 family.

419612:OLR1
gene id: 419612:OLR1
uniprot id: A0A8B6YM55
names: Subcellular Location Annotation
messages: Membrane

419612:PDGFRB
gene id: 419612:PDGFRB
uniprot id: A0A8B6Y6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Interacts with homodimeric PDGFB and PDGFD, and with heterodimers formed by PDGFA and PDGFB.
messages: Lysosome lumen
messages: Membrane
messages: Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
messages: Vesicle

419612:PPP1R2C
gene id: 419612:PPP1R2C
uniprot id: A0A8B6YP97
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

419612:ST6GALNAC4
gene id: 419612:ST6GALNAC4
uniprot id: A0A8B8SWH2
uniprot id: A0A8B8SWN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

419612:GBX1
gene id: 419612:GBX1
uniprot id: A0A8B8TAY7
names: Subcellular Location Annotation
messages: Nucleus

419612:ITPRIPL2
gene id: 419612:ITPRIPL2
uniprot id: A0A8B8RIC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

419612:LOC102504997
gene id: 419612:LOC102504997
uniprot id: A0A8B6YNX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:LOC102512018
gene id: 419612:LOC102512018
uniprot id: A0A8B8S517
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:NR1H3
gene id: 419612:NR1H3
uniprot id: A0A8B7KDT4
uniprot id: A0A8B7KFP0
uniprot id: A0A8B8TQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

419612:EIF4G1
gene id: 419612:EIF4G1
uniprot id: A0A8B8T9C5
uniprot id: A0A8B8T9E9
uniprot id: A0A8B8T9F6
uniprot id: A0A8B8T9S8
uniprot id: A0A8B8TAE2
uniprot id: A0A8B8TAE7
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

419612:IL24
gene id: 419612:IL24
uniprot id: A0A8B8RYC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

419612:CTNS
gene id: 419612:CTNS
uniprot id: A0A8B8UH49
uniprot id: A0A8B8UIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

419612:TRAPPC2
gene id: 419612:TRAPPC2
uniprot id: A0A8B8SNB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

419612:PPP1R9B
gene id: 419612:PPP1R9B
uniprot id: A0A8B8R6X1
names: Subcellular Location Annotation
messages: cytoskeleton

419612:ELAVL3
gene id: 419612:ELAVL3
uniprot id: A0A8B8RUI2
uniprot id: A0A8B8RVM7
uniprot id: A0A8B8RW33
names: Similarity
messages: Belongs to the RRM elav family.

419612:ELL2
gene id: 419612:ELL2
uniprot id: A0A8B8SS42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

419612:GNG8
gene id: 419612:GNG8
uniprot id: A0A8B7K3H8
uniprot id: A0A8B7K3Q2
uniprot id: A0A8B8TIJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

419612:GPR179
gene id: 419612:GPR179
uniprot id: A0A8B8R6Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:LOC116661683
gene id: 419612:LOC116661683
uniprot id: A0A8B8SJP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:EPHB6
gene id: 419612:EPHB6
uniprot id: A0A8B8TB46
uniprot id: A0A8B8TBD2
uniprot id: A0A8B8TC57
names: Subcellular Location Annotation
messages: Membrane

419612:XKR5
gene id: 419612:XKR5
uniprot id: A0A8B8S467
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

419612:ARHGAP33
gene id: 419612:ARHGAP33
uniprot id: A0A8B8TQ14
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

419612:ATP10B
gene id: 419612:ATP10B
uniprot id: A0A8B8RTU2
uniprot id: A0A8B8RUI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

419612:ABHD2
gene id: 419612:ABHD2
uniprot id: A0A8B6YP10
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

419612:FBLN2
gene id: 419612:FBLN2
uniprot id: A0A8B8R9G7
uniprot id: A0A8B8R9H6
uniprot id: A0A8B8R9L4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:PARD6A
gene id: 419612:PARD6A
uniprot id: A0A8B6YBR7
uniprot id: S9Y9Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

419612:SLC12A1
gene id: 419612:SLC12A1
uniprot id: A0A8B8T4E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

419612:PRAME
gene id: 419612:PRAME
uniprot id: A0A8B8SBD0
uniprot id: A0A8B8SDV9
names: Similarity
messages: Belongs to the PRAME family.

419612:LOC102505322
gene id: 419612:LOC102505322
uniprot id: A0A8B7KGD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SH2B3
gene id: 419612:SH2B3
uniprot id: A0A8B8SA60
uniprot id: A0A8B8SA61
uniprot id: A0A8B8SBD3
uniprot id: A0A8B8SBI1
names: Similarity
messages: Belongs to the SH2B adapter family.

419612:CDC42EP1
gene id: 419612:CDC42EP1
uniprot id: S9YLX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

419612:DUPD1
gene id: 419612:DUPD1
uniprot id: A0A8B7K953
uniprot id: A0A8B8TYS8
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

419612:CHD4
gene id: 419612:CHD4
uniprot id: A0A8B8SF03
uniprot id: A0A8B8SF07
uniprot id: A0A8B8SF11
uniprot id: A0A8B8SF12
uniprot id: A0A8B8SF18
uniprot id: A0A8B8SG66
uniprot id: A0A8B8SG72
uniprot id: A0A8B8SG77
uniprot id: A0A8B8SG93
uniprot id: A0A8B8SG98
uniprot id: A0A8B8SGA3
uniprot id: A0A8B8SHK9
uniprot id: A0A8B8SHL4
uniprot id: A0A8B8SHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

419612:LOC102509203
gene id: 419612:LOC102509203
uniprot id: A0A8B6YLR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ALB
gene id: 419612:ALB
uniprot id: A0A8B6YJ85
names: Subcellular Location Annotation
messages: Secreted

419612:UFM1
gene id: 419612:UFM1
uniprot id: A0A8B7K8J5
uniprot id: A0A8B7K8L0
names: Similarity
messages: Belongs to the UFM1 family.

419612:ADH6
gene id: 419612:ADH6
uniprot id: A0A8B6YQ22
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

419612:GDF7
gene id: 419612:GDF7
uniprot id: A0A8B8UF90
names: Similarity
messages: Belongs to the TGF-beta family.

419612:LOC102509150
gene id: 419612:LOC102509150
uniprot id: A0A8B8SLD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

419612:KIF16B
gene id: 419612:KIF16B
uniprot id: A0A8B8RIA1
uniprot id: A0A8B8RIA2
uniprot id: A0A8B8RIA8
uniprot id: A0A8B8RIA9
uniprot id: A0A8B8RIG9
uniprot id: A0A8B8RIH4
uniprot id: A0A8B8RK56
uniprot id: A0A8B8RK60
uniprot id: A0A8B8RKK4
uniprot id: A0A8B8RKK7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:TRAM1
gene id: 419612:TRAM1
uniprot id: A0A8B8S7F4
uniprot id: A0A8B8S8X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

419612:LOC102518454
gene id: 419612:LOC102518454
uniprot id: A0A8B8U9A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

419612:RPL7L1
gene id: 419612:RPL7L1
uniprot id: A0A8B7KE34
uniprot id: A0A8B7KF46
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

419612:GBE1
gene id: 419612:GBE1
uniprot id: A0A8B8ST60
uniprot id: A0A8B8SUP5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

419612:CIAO2B
gene id: 419612:CIAO2B
uniprot id: A0A8B6YBP7
names: Similarity
messages: Belongs to the MIP18 family.

419612:ZAN
gene id: 419612:ZAN
uniprot id: A0A8B8RGA8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:RSAD1
gene id: 419612:RSAD1
uniprot id: A0A8B8UHK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

419612:SLC4A11
gene id: 419612:SLC4A11
uniprot id: A0A8B8RIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

419612:PPARD
gene id: 419612:PPARD
uniprot id: S9X0Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

419612:RGS2
gene id: 419612:RGS2
uniprot id: A0A8B8RYY6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: nucleolus

419612:LOC116666633
gene id: 419612:LOC116666633
uniprot id: A0A8B8TVM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:INHBC
gene id: 419612:INHBC
uniprot id: S9Y6C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

419612:ABLIM3
gene id: 419612:ABLIM3
uniprot id: A0A8B8SS35
uniprot id: A0A8B8SS48
uniprot id: A0A8B8ST51
uniprot id: A0A8B8STU7
names: Subcellular Location Annotation
messages: Cytoplasm

419612:FGR
gene id: 419612:FGR
uniprot id: S9XND6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

419612:DNASE1
gene id: 419612:DNASE1
uniprot id: A0A8B6YA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

419612:DLK2
gene id: 419612:DLK2
uniprot id: A0A8B8RNX1
uniprot id: S9WLQ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:VWCE
gene id: 419612:VWCE
uniprot id: A0A8B8TT09
uniprot id: A0A8B8TT20
uniprot id: A0A8B8TT25
uniprot id: A0A8B8TT27
uniprot id: A0A8B8TU29
uniprot id: A0A8B8TU51
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:CTNNAL1
gene id: 419612:CTNNAL1
uniprot id: A0A8B8SVN9
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

419612:KCNK17
gene id: 419612:KCNK17
uniprot id: A0A8B8RLT7
uniprot id: A0A8B8RM32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

419612:LOC102505497
gene id: 419612:LOC102505497
uniprot id: S9XDG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TUBGCP4
gene id: 419612:TUBGCP4
uniprot id: A0A8B7K6G1
uniprot id: A0A8B8T4R1
uniprot id: A0A8B8T4R2
uniprot id: A0A8B8T5F7
uniprot id: A0A8B8T5K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

419612:LOC102510649
gene id: 419612:LOC102510649
uniprot id: A0A8B6YLR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RPL24
gene id: 419612:RPL24
uniprot id: A0A8B6YIW3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

419612:RNF146
gene id: 419612:RNF146
uniprot id: A0A8B6YP32
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

419612:CACNB2
gene id: 419612:CACNB2
uniprot id: A0A8B6YK49
uniprot id: A0A8B6YK78
uniprot id: A0A8B6YLJ5
uniprot id: A0A8B7KEP5
uniprot id: A0A8B8SH36
uniprot id: A0A8B8SH38
uniprot id: A0A8B8SI65
uniprot id: A0A8B8SIB2
uniprot id: A0A8B8SIB7
uniprot id: A0A8B8SJL4
uniprot id: A0A8B8SJL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: sarcolemma

419612:MYORG
gene id: 419612:MYORG
uniprot id: A0A8B8STQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

419612:LOC116658237
gene id: 419612:LOC116658237
uniprot id: A0A8B8RL67
names: Similarity
messages: Belongs to the heat shock protein 70 family.

419612:GPT
gene id: 419612:GPT
uniprot id: A0A8B8S0X6
uniprot id: A0A8B8S296
uniprot id: A0A8B8S2J9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

419612:PTPRS
gene id: 419612:PTPRS
uniprot id: A0A8B8RUT8
uniprot id: A0A8B8RUU1
uniprot id: A0A8B8RUU3
uniprot id: A0A8B8RUU7
uniprot id: A0A8B8RVY9
uniprot id: A0A8B8RVZ5
uniprot id: A0A8B8RWE3
uniprot id: A0A8B8RWF0
uniprot id: A0A8B8RWP3
uniprot id: A0A8B8RWP7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

419612:ARID3A
gene id: 419612:ARID3A
uniprot id: A0A8B8RWY7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

419612:SLC35A3
gene id: 419612:SLC35A3
uniprot id: A0A8B8TLE4
uniprot id: A0A8B8TLE6
uniprot id: A0A8B8TLS5
uniprot id: A0A8B8TMM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

419612:EFHC1
gene id: 419612:EFHC1
uniprot id: A0A8B8RMI4
uniprot id: A0A8B8RPN8
names: Subcellular Location Annotation
messages: cilium axoneme

419612:GPR157
gene id: 419612:GPR157
uniprot id: A0A8B8U8V1
uniprot id: A0A8B8U9N9
uniprot id: A0A8B8U9S9
names: Subcellular Location Annotation
messages: Membrane

419612:NECTIN4
gene id: 419612:NECTIN4
uniprot id: A0A8B6Y697
uniprot id: A0A8B7KCB1
uniprot id: A0A8B8RPA5
uniprot id: A0A8B8RR06
names: Similarity
messages: Belongs to the nectin family.

419612:ARPC5L
gene id: 419612:ARPC5L
uniprot id: A0A8B8SWE4
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

419612:SNRPN
gene id: 419612:SNRPN
uniprot id: A0A8B8S4E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

419612:RC3H1
gene id: 419612:RC3H1
uniprot id: A0A8B6Y5J1
uniprot id: A0A8B6Y8P0
uniprot id: A0A8B8RQH7
names: Subcellular Location Annotation
messages: P-body

419612:MED1
gene id: 419612:MED1
uniprot id: A0A8B6Y9B8
uniprot id: A0A8B8R739
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

419612:TMBIM1
gene id: 419612:TMBIM1
uniprot id: S9WV71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

419612:PRIMPOL
gene id: 419612:PRIMPOL
uniprot id: A0A8B8S269
uniprot id: A0A8B8S270
uniprot id: A0A8B8S3J2
uniprot id: A0A8B8S3S7
uniprot id: A0A8B8S3Y0
uniprot id: A0A8B8S3Y5
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

419612:DTX3L
gene id: 419612:DTX3L
uniprot id: A0A8B8T2C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

419612:PIK3C2G
gene id: 419612:PIK3C2G
uniprot id: A0A8B6YQQ0
uniprot id: A0A8B7KG19
uniprot id: A0A8B8SFY8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

419612:ANXA3
gene id: 419612:ANXA3
uniprot id: A0A8B8R579
uniprot id: A0A8B8R7X1
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

419612:IRX6
gene id: 419612:IRX6
uniprot id: A0A8B8TJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

419612:ELOC
gene id: 419612:ELOC
uniprot id: A0A8B6YGE6
names: Similarity
messages: Belongs to the SKP1 family.

419612:LOC102508006
gene id: 419612:LOC102508006
uniprot id: A0A8B7KEP2
uniprot id: A0A8B8RNJ6
names: Similarity
messages: Belongs to the MHC class I family.

419612:LOC102505310
gene id: 419612:LOC102505310
uniprot id: A0A8B6YJI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:POMT2
gene id: 419612:POMT2
uniprot id: A0A8B6YF37
uniprot id: A0A8B8T8T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

419612:VAPB
gene id: 419612:VAPB
uniprot id: A0A8B8RH89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:LOC102504986
gene id: 419612:LOC102504986
uniprot id: A0A8B6YS16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102519908
gene id: 419612:LOC102519908
uniprot id: A0A8B7KEY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SPC24
gene id: 419612:SPC24
uniprot id: A0A8B8RUD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

419612:FAM187B
gene id: 419612:FAM187B
uniprot id: A0A8B8TPR1
uniprot id: A0A8B8TQ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

419612:LLGL1
gene id: 419612:LLGL1
uniprot id: A0A8B8UJZ9
uniprot id: A0A8B8UK89
uniprot id: A0A8B8UKC2
uniprot id: A0A8B8UKE7
uniprot id: A0A8B8UL00
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

419612:C32H12orf49
gene id: 419612:C32H12orf49
uniprot id: A0A8B8SBI0
uniprot id: A0A8B8SE04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

419612:UMOD
gene id: 419612:UMOD
uniprot id: A0A8B8RHR1
names: Caution
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium membrane

419612:RCAN3
gene id: 419612:RCAN3
uniprot id: A0A8B8UAN7
uniprot id: A0A8B8UAU1
uniprot id: A0A8B8UB54
uniprot id: A0A8B8UB59
names: Similarity
messages: Belongs to the RCAN family.

419612:SLC34A2
gene id: 419612:SLC34A2
uniprot id: A0A8B6YMG6
uniprot id: A0A8B8U903
uniprot id: A0A8B8U927
uniprot id: S9WS72
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

419612:CCN4
gene id: 419612:CCN4
uniprot id: A0A8B8S0B5
uniprot id: A0A8B8S1W2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

419612:TSPAN1
gene id: 419612:TSPAN1
uniprot id: A0A8B6YB58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

419612:METTL2A
gene id: 419612:METTL2A
uniprot id: A0A8B8R4Y4
uniprot id: A0A8B8R7N0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

419612:STAG3
gene id: 419612:STAG3
uniprot id: A0A8B8RCB6
uniprot id: A0A8B8RED6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

419612:MDFI
gene id: 419612:MDFI
uniprot id: A0A8B8RP35
names: Similarity
messages: Belongs to the MDFI family.

419612:FLT3
gene id: 419612:FLT3
uniprot id: A0A8B8UCG9
uniprot id: A0A8B8UDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

419612:PDK1
gene id: 419612:PDK1
uniprot id: A0A8B8T0F1
uniprot id: A0A8B8T0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

419612:RNASE13
gene id: 419612:RNASE13
uniprot id: A0A8B6YPN3
uniprot id: S9WJX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

419612:POGLUT3
gene id: 419612:POGLUT3
uniprot id: A0A8B8SGX8
names: Similarity
messages: Belongs to the KDELC family.

419612:IL13RA2
gene id: 419612:IL13RA2
uniprot id: A0A8B8SLU6
uniprot id: A0A8B8SN08
names: Subcellular Location Annotation
messages: Membrane

419612:SLC25A41
gene id: 419612:SLC25A41
uniprot id: A0A8B6Y8Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:MRPL2
gene id: 419612:MRPL2
uniprot id: A0A8B6YPH9
uniprot id: A0A8B7KF40
uniprot id: A0A8B8RNU8
uniprot id: A0A8B8RP98
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

419612:DHX15
gene id: 419612:DHX15
uniprot id: A0A8B8U987
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

419612:IMPDH2
gene id: 419612:IMPDH2
uniprot id: A0A8B6Y6S4
uniprot id: A0A8B7KER0
uniprot id: A0A8B7KFL4
uniprot id: T0MFE2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

419612:ANAPC11
gene id: 419612:ANAPC11
uniprot id: A0A8B8R393
names: Similarity
messages: Belongs to the RING-box family.

419612:PPP1R16B
gene id: 419612:PPP1R16B
uniprot id: A0A8B8RM11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

419612:PPP2R5D
gene id: 419612:PPP2R5D
uniprot id: A0A8B6YKX9
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

419612:LOC102512311
gene id: 419612:LOC102512311
uniprot id: A0A8B6YLS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102517700
gene id: 419612:LOC102517700
uniprot id: A0A8B8T2W1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

419612:LOC102515976
gene id: 419612:LOC102515976
uniprot id: A0A8B7KE83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SMDT1
gene id: 419612:SMDT1
uniprot id: S9XK47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

419612:TM4SF5
gene id: 419612:TM4SF5
uniprot id: A0A8B8UJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

419612:LOC102509795
gene id: 419612:LOC102509795
uniprot id: A0A8B6YLF2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ART4
gene id: 419612:ART4
uniprot id: A0A8B6YM66
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

419612:TTC21B
gene id: 419612:TTC21B
uniprot id: A0A8B8SZP8
uniprot id: A0A8B8T0P2
names: Similarity
messages: Belongs to the TTC21 family.

419612:NOX3
gene id: 419612:NOX3
uniprot id: A0A8B8TGF9
names: Subcellular Location Annotation
messages: Membrane

419612:TWSG1
gene id: 419612:TWSG1
uniprot id: A0A8B8S141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

419612:CDK4
gene id: 419612:CDK4
uniprot id: A0A8B8U459
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:ANKRD13D
gene id: 419612:ANKRD13D
uniprot id: A0A8B8TU82
uniprot id: A0A8B8TU83
uniprot id: A0A8B8TU85
uniprot id: A0A8B8TVG1
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

419612:LOC102523797
gene id: 419612:LOC102523797
uniprot id: A0A8B7K4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:ZNF532
gene id: 419612:ZNF532
uniprot id: A0A8B7K8R3
uniprot id: A0A8B8S7X1
uniprot id: A0A8B8S971
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

419612:LOC102521473
gene id: 419612:LOC102521473
uniprot id: A0A8B8SL42
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

419612:LOC116665982
gene id: 419612:LOC116665982
uniprot id: A0A8B8TMK6
names: Subcellular Location Annotation
messages: Nucleus

419612:RPP14
gene id: 419612:RPP14
uniprot id: A0A8B7K9Y0
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

419612:CIBAR1
gene id: 419612:CIBAR1
uniprot id: A0A8B8S0T2
uniprot id: A0A8B8S253
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

419612:TM2D2
gene id: 419612:TM2D2
uniprot id: A0A8B6YE77
names: Subcellular Location Annotation
messages: Membrane

419612:LOC116661577
gene id: 419612:LOC116661577
uniprot id: A0A8B8SKJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:LOC102507511
gene id: 419612:LOC102507511
uniprot id: A0A8B6YSH6
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

419612:HSD17B3
gene id: 419612:HSD17B3
uniprot id: A0A8B6YLR8
uniprot id: A0A8B8STT5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:LOC102510267
gene id: 419612:LOC102510267
uniprot id: A0A8B7KER2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

419612:RABAC1
gene id: 419612:RABAC1
uniprot id: A0A8B7K5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

419612:MEGF8
gene id: 419612:MEGF8
uniprot id: A0A8B8TI10
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:TMCC2
gene id: 419612:TMCC2
uniprot id: A0A8B8RY75
uniprot id: A0A8B8RY86
uniprot id: A0A8B8RZL4
uniprot id: A0A8B8RZM6
uniprot id: A0A8B8RZV8
uniprot id: A0A8B8RZW4
names: Similarity
messages: Belongs to the TEX28 family.

419612:SPIN1
gene id: 419612:SPIN1
uniprot id: A0A8B8S9K6
uniprot id: A0A8B8SAS8
uniprot id: A0A8B8SBX5
names: Similarity
messages: Belongs to the SPIN/STSY family.

419612:HSPA6
gene id: 419612:HSPA6
uniprot id: S9Z0H4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

419612:TXNIP
gene id: 419612:TXNIP
uniprot id: S9XHG6
names: Similarity
messages: Belongs to the arrestin family.

419612:LOC102511542
gene id: 419612:LOC102511542
uniprot id: A0A8B8SJ44
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:TGIF1
gene id: 419612:TGIF1
uniprot id: A0A8B7KFL6
uniprot id: A0A8B8RYH8
uniprot id: T0NU58
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102523825
gene id: 419612:LOC102523825
uniprot id: S9X6I9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:TOB2
gene id: 419612:TOB2
uniprot id: A0A8B6Y6G6
names: Similarity
messages: Belongs to the BTG family.

419612:DLL3
gene id: 419612:DLL3
uniprot id: A0A8B8TIA1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC102505930
gene id: 419612:LOC102505930
uniprot id: A0A8B8U822
uniprot id: A0A8B8U960
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

419612:SERPINA7
gene id: 419612:SERPINA7
uniprot id: A0A8B8SLH1
names: Similarity
messages: Belongs to the serpin family.

419612:TAFA2
gene id: 419612:TAFA2
uniprot id: A0A8B7KG84
names: Similarity
messages: Belongs to the TAFA family.

419612:CHRNA2
gene id: 419612:CHRNA2
uniprot id: A0A8B8S9F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:PKD1L2
gene id: 419612:PKD1L2
uniprot id: A0A8B6YEN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC116668140
gene id: 419612:LOC116668140
uniprot id: A0A8B8U7S3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

419612:LOC102512549
gene id: 419612:LOC102512549
uniprot id: A0A8B7KAM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:KRT12
gene id: 419612:KRT12
uniprot id: A0A8B6YI39
names: Similarity
messages: Belongs to the intermediate filament family.

419612:DIP2A
gene id: 419612:DIP2A
uniprot id: A0A8B8TKA0
uniprot id: A0A8B8TKH0
uniprot id: A0A8B8TKK6
uniprot id: A0A8B8TKW9
uniprot id: A0A8B8TL29
uniprot id: A0A8B8TLF0
uniprot id: A0A8B8TLG4
uniprot id: A0A8B8TLI8
uniprot id: A0A8B8TLM6
uniprot id: A0A8B8TLN5
uniprot id: A0A8B8TLU4
uniprot id: A0A8B8TM51
names: Similarity
messages: Belongs to the DIP2 family.

419612:SBNO2
gene id: 419612:SBNO2
uniprot id: A0A8B8RVP3
uniprot id: A0A8B8RWW4
uniprot id: A0A8B8RX75
names: Similarity
messages: Belongs to the SBNO family.

419612:EIF4A3
gene id: 419612:EIF4A3
uniprot id: A0A8B8R3H3
names: Similarity
messages: Belongs to the DEAD box helicase family.

419612:EIF2B5
gene id: 419612:EIF2B5
uniprot id: A0A8B6YE42
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

419612:GPR137
gene id: 419612:GPR137
uniprot id: A0A8B8TUK9
uniprot id: S9YHL3
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

419612:PSPC1
gene id: 419612:PSPC1
uniprot id: A0A8B8UCW4
uniprot id: A0A8B8UDL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

419612:DPYSL5
gene id: 419612:DPYSL5
uniprot id: A0A8B8UFL2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

419612:SBK2
gene id: 419612:SBK2
uniprot id: A0A8B8TGI7
uniprot id: A0A8B8TGJ2
names: Similarity
messages: Belongs to the protein kinase superfamily.

419612:EEF1AKMT1
gene id: 419612:EEF1AKMT1
uniprot id: S9YSY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

419612:CDH12
gene id: 419612:CDH12
uniprot id: A0A8B6YJP9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

419612:OXTR
gene id: 419612:OXTR
uniprot id: A0A8B8R9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

419612:RPL7A
gene id: 419612:RPL7A
uniprot id: A0A8B8SYM0
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

419612:GRIA1
gene id: 419612:GRIA1
uniprot id: A0A8B6YP95
uniprot id: A0A8B6YPD4
uniprot id: A0A8B8SSD2
uniprot id: A0A8B8SU32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

419612:SFPQ
gene id: 419612:SFPQ
uniprot id: A0A8B8UB18
names: Subcellular Location Annotation
messages: Nucleus speckle

419612:PICALM
gene id: 419612:PICALM
uniprot id: A0A8B8TR13
uniprot id: A0A8B8TR15
uniprot id: A0A8B8TR16
uniprot id: A0A8B8TR18
uniprot id: A0A8B8TR19
uniprot id: A0A8B8TR20
uniprot id: A0A8B8TR24
uniprot id: A0A8B8TRS9
uniprot id: A0A8B8TRT6
uniprot id: A0A8B8TS53
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

419612:CXCR6
gene id: 419612:CXCR6
uniprot id: S9YNM1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:MAP3K9
gene id: 419612:MAP3K9
uniprot id: A0A8B6YFZ3
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

419612:ARGFX
gene id: 419612:ARGFX
uniprot id: A0A8B8T4L0
names: Subcellular Location Annotation
messages: Nucleus

419612:CXXC5
gene id: 419612:CXXC5
uniprot id: A0A8B8SSK7
names: Subcellular Location Annotation
messages: Cytoplasm

419612:GABRP
gene id: 419612:GABRP
uniprot id: A0A8B6YLC7
uniprot id: A0A8B7KGH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:LOC102509876
gene id: 419612:LOC102509876
uniprot id: A0A8B8RFV8
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102523770
gene id: 419612:LOC102523770
uniprot id: A0A8B7K6B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCO1/2 family.
messages: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
messages: Homodimer.
messages: Mitochondrion inner membrane

419612:DLL4
gene id: 419612:DLL4
uniprot id: A0A8B8T559
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

419612:TAFA4
gene id: 419612:TAFA4
uniprot id: A0A8B8R7N7
names: Similarity
messages: Belongs to the TAFA family.

419612:CD55
gene id: 419612:CD55
uniprot id: A0A8B7KGN7
uniprot id: A0A8B7KGR5
uniprot id: A0A8B7KHZ5
uniprot id: A0A8B7KIS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:ADAMTS2
gene id: 419612:ADAMTS2
uniprot id: A0A8B8RS78
uniprot id: A0A8B8RTU3
uniprot id: A0A8B8RU52
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:BCLAF1
gene id: 419612:BCLAF1
uniprot id: A0A8B6YJ17
uniprot id: A0A8B6YMN4
uniprot id: A0A8B7KCF4
uniprot id: A0A8B7KCG7
uniprot id: A0A8B8TF79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCLAF1/THRAP3 family.
messages: Belongs to the CASC3 family.
messages: Cytoplasm
messages: Nucleus

419612:CHRNA4
gene id: 419612:CHRNA4
uniprot id: A0A8B8RHN0
uniprot id: A0A8B8RHN7
uniprot id: A0A8B8RHV4
uniprot id: A0A8B8RJJ8
uniprot id: A0A8B8RJZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:LOC102517598
gene id: 419612:LOC102517598
uniprot id: S9WCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102519504
gene id: 419612:LOC102519504
uniprot id: A0A8B8UH60
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

419612:NRP2
gene id: 419612:NRP2
uniprot id: A0A8B6YNW7
uniprot id: A0A8B6YQE6
uniprot id: A0A8B6YSA8
uniprot id: A0A8B8T1T7
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:GSTM4
gene id: 419612:GSTM4
uniprot id: A0A8B6YQ07
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

419612:CUL5
gene id: 419612:CUL5
uniprot id: A0A8B8SFM6
names: Similarity
messages: Belongs to the cullin family.

419612:GPR21
gene id: 419612:GPR21
uniprot id: A0A8B8SWB6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:DDX17
gene id: 419612:DDX17
uniprot id: A0A8B8U0P2
uniprot id: A0A8B8U1Z2
names: Similarity
messages: Belongs to the DEAD box helicase family.

419612:HUWE1
gene id: 419612:HUWE1
uniprot id: A0A8B8SMF1
uniprot id: A0A8B8SMF2
uniprot id: A0A8B8SMF7
uniprot id: A0A8B8SMF8
uniprot id: A0A8B8SNG1
uniprot id: A0A8B8SNG9
uniprot id: A0A8B8SNR7
uniprot id: A0A8B8SNS3
uniprot id: A0A8B8SPL8
names: Similarity
messages: Belongs to the UPL family. TOM1/PTR1 subfamily.

419612:HINT2
gene id: 419612:HINT2
uniprot id: A0A8B8SUT0
names: Similarity
messages: Belongs to the HINT family.

419612:LOC116669152
gene id: 419612:LOC116669152
uniprot id: A0A8B8UHU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

419612:PLXNA3
gene id: 419612:PLXNA3
uniprot id: A0A8B8SKI9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:NOTCH4
gene id: 419612:NOTCH4
uniprot id: A0A8B8RKZ5
uniprot id: A0A8B8RKZ9
uniprot id: A0A8B8RLA3
uniprot id: A0A8B8RN75
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

419612:GSDMB
gene id: 419612:GSDMB
uniprot id: A0A8B8R763
uniprot id: A0A8B8R769
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

419612:ALDH18A1
gene id: 419612:ALDH18A1
uniprot id: A0A8B8TXY0
uniprot id: A0A8B8TXY5
uniprot id: A0A8B8TXY6
uniprot id: A0A8B8TXZ3
uniprot id: A0A8B8TYY9
uniprot id: A0A8B8TYZ4
uniprot id: A0A8B8TZA2
uniprot id: A0A8B8TZA7
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

419612:NRTN
gene id: 419612:NRTN
uniprot id: A0A8B8RWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

419612:LOC102506310
gene id: 419612:LOC102506310
uniprot id: S9WVH6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:KCNU1
gene id: 419612:KCNU1
uniprot id: A0A8B8S3V5
names: Subcellular Location Annotation
messages: Membrane

419612:ETV7
gene id: 419612:ETV7
uniprot id: A0A8B6YPL1
uniprot id: A0A8B7KGJ1
uniprot id: A0A8B8RLM7
uniprot id: A0A8B8RLX6
uniprot id: A0A8B8RNT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

419612:DAND5
gene id: 419612:DAND5
uniprot id: A0A8B6YB41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

419612:SERPINF1
gene id: 419612:SERPINF1
uniprot id: T0MIJ2
names: Similarity
messages: Belongs to the serpin family.

419612:CEPT1
gene id: 419612:CEPT1
uniprot id: A0A8B7K8S5
uniprot id: A0A8B7K941
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

419612:PIH1D1
gene id: 419612:PIH1D1
uniprot id: A0A8B8TI11
names: Similarity
messages: Belongs to the PIH1 family.

419612:GANAB
gene id: 419612:GANAB
uniprot id: A0A8B6YCQ3
uniprot id: A0A8B6YD41
uniprot id: A0A8B8TT88
uniprot id: A0A8B8TUB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

419612:LNPK
gene id: 419612:LNPK
uniprot id: A0A8B8T016
uniprot id: A0A8B8T017
uniprot id: A0A8B8T0G9
uniprot id: A0A8B8T0I6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

419612:KIF24
gene id: 419612:KIF24
uniprot id: A0A8B7KAQ8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:NCDN
gene id: 419612:NCDN
uniprot id: A0A8B6YGX0
uniprot id: A0A8B8UB23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

419612:MFSD4B
gene id: 419612:MFSD4B
uniprot id: A0A8B6YHW7
names: Subcellular Location Annotation
messages: Membrane

419612:DHX9
gene id: 419612:DHX9
uniprot id: A0A8B8RNE1
uniprot id: A0A8B8RNT1
uniprot id: A0A8B8RQI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

419612:SCNN1A
gene id: 419612:SCNN1A
uniprot id: A0A8B6Y8S1
uniprot id: A0A8B7K468
uniprot id: A0A8B8SEV1
uniprot id: A0A8B8SEV3
uniprot id: A0A8B8SEW2
uniprot id: A0A8B8SG14
uniprot id: A0A8B8SG20
uniprot id: A0A8B8SG33
uniprot id: A0A8B8SG39
uniprot id: A0A8B8SHF6
uniprot id: A0A8B8SHG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

419612:WSCD1
gene id: 419612:WSCD1
uniprot id: A0A8B8UJQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Golgi apparatus membrane
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

419612:RARA
gene id: 419612:RARA
uniprot id: A0A8B8R7A7
uniprot id: A0A8B8R9F0
uniprot id: A0A8B8RA36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

419612:KDSR
gene id: 419612:KDSR
uniprot id: A0A8B8SAK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

419612:LOC102518954
gene id: 419612:LOC102518954
uniprot id: A0A8B7KF97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:GPR142
gene id: 419612:GPR142
uniprot id: A0A8B6Y877
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:HTRA4
gene id: 419612:HTRA4
uniprot id: A0A8B8S3L1
names: Similarity
messages: Belongs to the peptidase S1C family.

419612:LOC102505507
gene id: 419612:LOC102505507
uniprot id: A0A8B6YA56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:HS6ST2
gene id: 419612:HS6ST2
uniprot id: A0A8B8SJJ0
uniprot id: A0A8B8SKM4
uniprot id: A0A8B8SKY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

419612:FGF7
gene id: 419612:FGF7
uniprot id: A0A8B6YMB3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

419612:ABCC4
gene id: 419612:ABCC4
uniprot id: A0A8B8UDK1
uniprot id: A0A8B8UEB1
names: Subcellular Location Annotation
messages: Membrane

419612:TPT1
gene id: 419612:TPT1
uniprot id: A0A8B8UD23
names: Similarity
messages: Belongs to the TCTP family.

419612:INCENP
gene id: 419612:INCENP
uniprot id: A0A8B8TT68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Midbody
messages: Nucleus
messages: kinetochore
messages: spindle

419612:ARMC8
gene id: 419612:ARMC8
uniprot id: A0A8B8TN22
uniprot id: A0A8B8TNL8
uniprot id: A0A8B8TPA2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

419612:LOC102507550
gene id: 419612:LOC102507550
uniprot id: A0A8B6Y4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SPTBN2
gene id: 419612:SPTBN2
uniprot id: A0A8B8TU50
names: Similarity
messages: Belongs to the spectrin family.

419612:STING1
gene id: 419612:STING1
uniprot id: A0A8B7K510
uniprot id: A0A8B8SRH0
uniprot id: A0A8B8SSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Mitochondrion outer membrane
messages: autophagosome membrane
messages: perinuclear region

419612:BCO1
gene id: 419612:BCO1
uniprot id: A0A8B6YEZ7
uniprot id: A0A8B7K9P2
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

419612:LOC102508380
gene id: 419612:LOC102508380
uniprot id: S9WWK8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:CES2
gene id: 419612:CES2
uniprot id: A0A8B6YD14
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

419612:MMP20
gene id: 419612:MMP20
uniprot id: A0A8B6YKS3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

419612:GPAT4
gene id: 419612:GPAT4
uniprot id: A0A8B8S3A3
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

419612:SEMA3G
gene id: 419612:SEMA3G
uniprot id: A0A8B6YBM4
uniprot id: A0A8B7K923
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC106730797
gene id: 419612:LOC106730797
uniprot id: A0A8B8SP43
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

419612:CNIH1
gene id: 419612:CNIH1
uniprot id: A0A8B8T7P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

419612:NOP53
gene id: 419612:NOP53
uniprot id: A0A8B8TH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: nucleolus
messages: nucleoplasm

419612:TGFB1I1
gene id: 419612:TGFB1I1
uniprot id: A0A8B8RE68
uniprot id: A0A8B8RG77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: cytoskeleton
messages: focal adhesion

419612:ATP1B2
gene id: 419612:ATP1B2
uniprot id: A0A8B8UJ60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

419612:NHS
gene id: 419612:NHS
uniprot id: A0A8B8SM63
uniprot id: A0A8B8SN78
uniprot id: A0A8B8SNI0
names: Similarity
messages: Belongs to the NHS family.

419612:DRD2
gene id: 419612:DRD2
uniprot id: A0A8B6Y9V4
uniprot id: A0A8B6YCD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

419612:FOXL3
gene id: 419612:FOXL3
uniprot id: A0A8B8RCJ1
uniprot id: A0A8B8RCK7
names: Subcellular Location Annotation
messages: Nucleus

419612:KEG61 p07
gene id: 419612:KEG61_p07
uniprot id: A6YAS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

419612:REM2
gene id: 419612:REM2
uniprot id: A0A8B8T5R3
uniprot id: A0A8B8T6D1
names: Subcellular Location Annotation
messages: Cell membrane

419612:TBCCD1
gene id: 419612:TBCCD1
uniprot id: A0A8B6YJB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

419612:CTH
gene id: 419612:CTH
uniprot id: A0A8B6YL35
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

419612:GTPBP8
gene id: 419612:GTPBP8
uniprot id: A0A8B6Y682
uniprot id: A0A8B8SZT4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

419612:SPIN3
gene id: 419612:SPIN3
uniprot id: S9W8U2
names: Similarity
messages: Belongs to the SPIN/STSY family.

419612:TSNAX
gene id: 419612:TSNAX
uniprot id: A0A8B6YEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

419612:CFAP206
gene id: 419612:CFAP206
uniprot id: A0A8B8TDZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme

419612:KCNQ1
gene id: 419612:KCNQ1
uniprot id: A0A8B8TUQ9
uniprot id: A0A8B8TUR1
uniprot id: A0A8B8TVT8
uniprot id: A0A8B8TVZ9
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

419612:ELP3
gene id: 419612:ELP3
uniprot id: A0A8B6YDJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

419612:LOC102504726
gene id: 419612:LOC102504726
uniprot id: A0A8B8U788
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

419612:LRP1B
gene id: 419612:LRP1B
uniprot id: A0A8B8SZH6
uniprot id: A0A8B8SZI6
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MARK4
gene id: 419612:MARK4
uniprot id: A0A8B8TIS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

419612:LOC116657545
gene id: 419612:LOC116657545
uniprot id: A0A8B8RE09
uniprot id: A0A8B8RG25
names: Similarity
messages: Belongs to the KHDC1 family.

419612:PCSK9
gene id: 419612:PCSK9
uniprot id: A0A8B8U7S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Endosome
messages: Golgi apparatus
messages: Lysosome

419612:MAML1
gene id: 419612:MAML1
uniprot id: A0A8B8RU40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

419612:AP4E1
gene id: 419612:AP4E1
uniprot id: A0A8B6YCB7
names: Function
names: Similarity
names: Subunit
messages: Adaptor protein complex 4 (AP-4) is a heterotetramer composed of two large adaptins, a medium adaptin and a small adaptin.
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.

419612:P3H3
gene id: 419612:P3H3
uniprot id: A0A8B8SHL2
uniprot id: A0A8B8SHP5
names: Similarity
messages: Belongs to the leprecan family.

419612:TFAP2D
gene id: 419612:TFAP2D
uniprot id: A0A8B8RJX2
names: Similarity
messages: Belongs to the AP-2 family.

419612:KATNAL2
gene id: 419612:KATNAL2
uniprot id: A0A8B6YIL7
uniprot id: A0A8B7K9L5
uniprot id: A0A8B7K9W3
uniprot id: A0A8B8S8S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

419612:DUSP5
gene id: 419612:DUSP5
uniprot id: A0A8B8TX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

419612:RIN2
gene id: 419612:RIN2
uniprot id: A0A8B8RI60
uniprot id: A0A8B8RI65
uniprot id: A0A8B8RIC6
uniprot id: A0A8B8RID1
uniprot id: A0A8B8RK20
uniprot id: A0A8B8RKH0
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

419612:LOC102518756
gene id: 419612:LOC102518756
uniprot id: A0A8B8S4A9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:GINS1
gene id: 419612:GINS1
uniprot id: A0A8B8RI70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS4. GINS complex interacts with DNA primase in vitro. Component of the CMG helicase complex, a hexameric ring of related MCM2-7 subunits stabilized by CDC45 and the tetrameric GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

419612:KRT20
gene id: 419612:KRT20
uniprot id: A0A8B7KBS3
uniprot id: A0A8B8UIU7
names: Similarity
messages: Belongs to the intermediate filament family.

419612:C1D
gene id: 419612:C1D
uniprot id: A0A8B6YMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

419612:LOC102504631
gene id: 419612:LOC102504631
uniprot id: A0A8B8SJQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:QPRT
gene id: 419612:QPRT
uniprot id: A0A8B6YGJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

419612:SLC39A14
gene id: 419612:SLC39A14
uniprot id: A0A8B8SA20
uniprot id: A0A8B8SB88
uniprot id: A0A8B8SCE6
names: Subcellular Location Annotation
messages: Membrane

419612:SF3A2
gene id: 419612:SF3A2
uniprot id: A0A8B8RWL5
names: Similarity
messages: Belongs to the SF3A2 family.

419612:CCDC149
gene id: 419612:CCDC149
uniprot id: A0A8B8U8G6
uniprot id: A0A8B8U8J9
uniprot id: A0A8B8U9H4
uniprot id: A0A8B8U9N5
names: Similarity
messages: Belongs to the CCDC149 family.

419612:ADORA1
gene id: 419612:ADORA1
uniprot id: A0A8B7K5L5
uniprot id: A0A8B8RXD7
uniprot id: A0A8B8RYT4
uniprot id: S9YES8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

419612:TPM3
gene id: 419612:TPM3
uniprot id: A0A8B6Y8E8
uniprot id: A0A8B6Y8R9
uniprot id: A0A8B6Y938
uniprot id: A0A8B6Y943
uniprot id: A0A8B6Y9Z3
uniprot id: A0A8B6YCH6
uniprot id: A0A8B6YCI1
uniprot id: A0A8B7K4S9
uniprot id: A0A8B7K764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

419612:PHF5A
gene id: 419612:PHF5A
uniprot id: A0A8B6Y850
names: Similarity
messages: Belongs to the PHF5 family.

419612:TMEM256
gene id: 419612:TMEM256
uniprot id: A0A8B6YBB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

419612:KIF4A
gene id: 419612:KIF4A
uniprot id: A0A8B8SLF1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:LOC106728443
gene id: 419612:LOC106728443
uniprot id: A0A8B7KAD6
names: Similarity
names: Subunit
messages: Belongs to the PIP family.
messages: Monomer. Interacts with AZGP1.

419612:ACSF2
gene id: 419612:ACSF2
uniprot id: A0A8B8UHF2
uniprot id: A0A8B8UI08
uniprot id: A0A8B8UI10
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

419612:FAM234A
gene id: 419612:FAM234A
uniprot id: A0A8B8RH36
names: Similarity
messages: Belongs to the FAM234 family.

419612:YARS1
gene id: 419612:YARS1
uniprot id: A0A8B6Y7K6
uniprot id: A0A8B8UC71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

419612:LOC102515270
gene id: 419612:LOC102515270
uniprot id: A0A8B8R6J7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

419612:ARL6IP5
gene id: 419612:ARL6IP5
uniprot id: S9XTG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

419612:LAMC1
gene id: 419612:LAMC1
uniprot id: A0A8B6YRE3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

419612:ATP4A
gene id: 419612:ATP4A
uniprot id: A0A8B8TNW4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

419612:LOC102522994
gene id: 419612:LOC102522994
uniprot id: A0A8B6YE07
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PAX4
gene id: 419612:PAX4
uniprot id: A0A8B8TDK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

419612:CSTF2
gene id: 419612:CSTF2
uniprot id: A0A8B6YM57
uniprot id: A0A8B7KEY1
names: Subcellular Location Annotation
messages: Nucleus

419612:TMED6
gene id: 419612:TMED6
uniprot id: A0A8B6YFP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:PALM
gene id: 419612:PALM
uniprot id: A0A8B8RVV3
names: Similarity
messages: Belongs to the paralemmin family.

419612:LOC102506678
gene id: 419612:LOC102506678
uniprot id: A0A8B6YK97
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

419612:LOC102517230
gene id: 419612:LOC102517230
uniprot id: A0A8B6YK04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102508075
gene id: 419612:LOC102508075
uniprot id: A0A8B7KGI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SLC28A1
gene id: 419612:SLC28A1
uniprot id: A0A8B7KFA9
uniprot id: A0A8B8S4G8
uniprot id: A0A8B8S5S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

419612:ARCN1
gene id: 419612:ARCN1
uniprot id: A0A8B8SFM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

419612:CHMP7
gene id: 419612:CHMP7
uniprot id: A0A8B8SAQ8
names: Similarity
messages: Belongs to the SNF7 family.

419612:MRPL28
gene id: 419612:MRPL28
uniprot id: A0A8B8RF48
uniprot id: A0A8B8RFB7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

419612:BLK
gene id: 419612:BLK
uniprot id: A0A8B8S902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

419612:LOC102517053
gene id: 419612:LOC102517053
uniprot id: A0A8B8RX19
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

419612:LDLR
gene id: 419612:LDLR
uniprot id: A0A8B6YJJ7
uniprot id: A0A8B8RVY7
uniprot id: A0A8B8RW92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC116661572
gene id: 419612:LOC116661572
uniprot id: A0A8B8SJD4
names: Similarity
messages: Belongs to the DPH3 family.

419612:LOC102513504
gene id: 419612:LOC102513504
uniprot id: A0A8B6YG47
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

419612:ZHX2
gene id: 419612:ZHX2
uniprot id: S9X2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

419612:LOC102520645
gene id: 419612:LOC102520645
uniprot id: A0A8B7KER3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

419612:FAT2
gene id: 419612:FAT2
uniprot id: A0A8B8SSZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC102520817
gene id: 419612:LOC102520817
uniprot id: A0A8B8TVW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:LOC116658799
gene id: 419612:LOC116658799
uniprot id: A0A8B8RRQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom22 family.
messages: Mitochondrion outer membrane

419612:PPM1K
gene id: 419612:PPM1K
uniprot id: A0A8B6Y725
names: Similarity
messages: Belongs to the PP2C family.

419612:GFM1
gene id: 419612:GFM1
uniprot id: A0A8B6YK96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

419612:LIAS
gene id: 419612:LIAS
uniprot id: A0A8B6YJG7
uniprot id: A0A8B6YN46
uniprot id: A0A8B8UBH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

419612:TNFAIP1
gene id: 419612:TNFAIP1
uniprot id: A0A8B6YGT4
names: Similarity
messages: Belongs to the BACURD family.

419612:CPNE3
gene id: 419612:CPNE3
uniprot id: A0A8B7KFT8
names: Similarity
messages: Belongs to the copine family.

419612:UTS2R
gene id: 419612:UTS2R
uniprot id: A0A8B8UKD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

419612:CAPRIN1
gene id: 419612:CAPRIN1
uniprot id: A0A8B8TR46
names: Similarity
messages: Belongs to the caprin family.

419612:PPM1N
gene id: 419612:PPM1N
uniprot id: A0A8B8THH4
names: Similarity
messages: Belongs to the PP2C family.

419612:TFIP11
gene id: 419612:TFIP11
uniprot id: S9WW95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFP11/STIP family.
messages: Identified in the spliceosome C complex. Found in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors. Interacts with TUFT1. Interacts with DHX15; indicative for a recruitment of DHX15 to the IL complex. Interacts with GCFC2.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
messages: Nucleus

419612:C22H19orf53
gene id: 419612:C22H19orf53
uniprot id: S9XK14
names: Function
names: Similarity
messages: Belongs to the UPF0390 family.
messages: May have a potential role in hypercalcemia of malignancy.

419612:AURKAIP1
gene id: 419612:AURKAIP1
uniprot id: A0A8B7K3X9
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

419612:ADAMTS7
gene id: 419612:ADAMTS7
uniprot id: A0A8B8S5P0
uniprot id: A0A8B8S629
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:LOC102524456
gene id: 419612:LOC102524456
uniprot id: A0A8B8SU26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

419612:ATP7A
gene id: 419612:ATP7A
uniprot id: A0A8B8SQ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

419612:AGBL3
gene id: 419612:AGBL3
uniprot id: A0A8B8TAN9
uniprot id: A0A8B8TAY5
uniprot id: A0A8B8TAY9
uniprot id: A0A8B8TBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

419612:VRTN
gene id: 419612:VRTN
uniprot id: S9WSF2
names: Similarity
messages: Belongs to the vertnin family.

419612:CCL24
gene id: 419612:CCL24
uniprot id: A0A8B8RBW2
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

419612:CCDC93
gene id: 419612:CCDC93
uniprot id: A0A8B8SYT5
uniprot id: A0A8B8SYV9
uniprot id: A0A8B8SZC3
uniprot id: A0A8B8SZX3
names: Similarity
messages: Belongs to the CCDC93 family.

419612:JAK3
gene id: 419612:JAK3
uniprot id: A0A8B6Y7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

419612:RAB3C
gene id: 419612:RAB3C
uniprot id: A0A8B6YBW7
uniprot id: A0A8B7K7D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

419612:NOP10
gene id: 419612:NOP10
uniprot id: A0A8B6YPB5
names: Similarity
messages: Belongs to the NOP10 family.

419612:TAF1B
gene id: 419612:TAF1B
uniprot id: A0A8B8UF14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
messages: nucleolus

419612:SAE1
gene id: 419612:SAE1
uniprot id: A0A8B6YM38
uniprot id: A0A8B6YPF3
uniprot id: A0A8B7KDS9
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

419612:LOC102513416
gene id: 419612:LOC102513416
uniprot id: A0A8B8SFT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

419612:SPG7
gene id: 419612:SPG7
uniprot id: A0A8B8RRF7
uniprot id: A0A8B8RT40
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

419612:LOC102517659
gene id: 419612:LOC102517659
uniprot id: A0A8B8UAW8
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

419612:LOC102522362
gene id: 419612:LOC102522362
uniprot id: A0A8B8RTD0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102515239
gene id: 419612:LOC102515239
uniprot id: A0A8B6YAY7
names: Similarity
messages: Belongs to the transferrin family.

419612:U2AF2
gene id: 419612:U2AF2
uniprot id: A0A8B8TMJ8
uniprot id: A0A8B8TML1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

419612:B2M
gene id: 419612:B2M
uniprot id: S9WVH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

419612:METTL11B
gene id: 419612:METTL11B
uniprot id: A0A8B6Y5S2
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

419612:A1CF
gene id: 419612:A1CF
uniprot id: A0A8B8TYC3
uniprot id: A0A8B8TYC4
uniprot id: A0A8B8TYE2
uniprot id: A0A8B8TZC4
uniprot id: A0A8B8TZC9
uniprot id: A0A8B8TZN1
uniprot id: A0A8B8TZN4
uniprot id: A0A8B8TZN9
names: Subcellular Location Annotation
messages: Cytoplasm

419612:FAM20A
gene id: 419612:FAM20A
uniprot id: A0A8B8R4F4
uniprot id: A0A8B8R751
names: Similarity
messages: Belongs to the FAM20 family.

419612:IZUMO2
gene id: 419612:IZUMO2
uniprot id: A0A8B6Y645
uniprot id: A0A8B7KB63
names: Similarity
messages: Belongs to the Izumo family.

419612:OTC
gene id: 419612:OTC
uniprot id: A0A8B6YQL1
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

419612:TGFBR2
gene id: 419612:TGFBR2
uniprot id: A0A8B8RBA9
uniprot id: A0A8B8RDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

419612:ACADL
gene id: 419612:ACADL
uniprot id: A0A8B8T0Q1
uniprot id: A0A8B8T1M6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix

419612:GSTM3
gene id: 419612:GSTM3
uniprot id: A0A8B6YSP2
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

419612:SLC11A2
gene id: 419612:SLC11A2
uniprot id: A0A8B8U2C2
uniprot id: A0A8B8U2V6
uniprot id: A0A8B8U3K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Macrophage-specific antiporter that fluxes metal ions in either direction against a proton gradient. Localized to late endosomal lysosomal membranes, delivers bivalent cations from the cytosol into these acidic compartments where they may directly affect antimicrobial activity. Involved in iron metabolism and host natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

419612:XPOT
gene id: 419612:XPOT
uniprot id: A0A8B8U3P3
uniprot id: A0A8B8U4E5
uniprot id: A0A8B8U4N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

419612:IRX3
gene id: 419612:IRX3
uniprot id: A0A8B8TJ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

419612:AQP7
gene id: 419612:AQP7
uniprot id: A0A8B6YEV6
uniprot id: A0A8B7K8K9
uniprot id: A0A8B7KAQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

419612:GCGR
gene id: 419612:GCGR
uniprot id: A0A8B8R324
uniprot id: A0A8B8R330
uniprot id: A0A8B8R343
uniprot id: A0A8B8R398
uniprot id: A0A8B8R5F2
uniprot id: A0A8B8R5U8
uniprot id: A0A8B8R5V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

419612:TREX1
gene id: 419612:TREX1
uniprot id: A0A8B6Y6H4
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

419612:GCNT2
gene id: 419612:GCNT2
uniprot id: A0A8B7K7J0
uniprot id: A0A8B7K815
uniprot id: A0A8B8RKA7
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

419612:CRYZ
gene id: 419612:CRYZ
uniprot id: A0A8B6Y9I5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

419612:FAM166C
gene id: 419612:FAM166C
uniprot id: S9WMI8
names: Similarity
messages: Belongs to the CIMIP2 family.

419612:PPP1CC
gene id: 419612:PPP1CC
uniprot id: A0A8B8SC24
uniprot id: A0A8B8SDD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

419612:PRKAB2
gene id: 419612:PRKAB2
uniprot id: A0A8B7KF78
uniprot id: A0A8B8TKQ4
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

419612:LOC102506225
gene id: 419612:LOC102506225
uniprot id: S9X6K0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:SH3GL1
gene id: 419612:SH3GL1
uniprot id: A0A8B8RWJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

419612:ZNF706
gene id: 419612:ZNF706
uniprot id: A0A8B8S3C8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

419612:LOC106728829
gene id: 419612:LOC106728829
uniprot id: A0A8B8SMM7
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

419612:OCSTAMP
gene id: 419612:OCSTAMP
uniprot id: A0A8B8RIS6
names: Subcellular Location Annotation
messages: Membrane

419612:MED7
gene id: 419612:MED7
uniprot id: A0A8B6Y880
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

419612:ATG5
gene id: 419612:ATG5
uniprot id: A0A8B7KD05
uniprot id: A0A8B7KE65
uniprot id: A0A8B8TE47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

419612:MINDY3
gene id: 419612:MINDY3
uniprot id: A0A8B6YFJ3
uniprot id: A0A8B8SHN9
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

419612:LPXN
gene id: 419612:LPXN
uniprot id: A0A8B6Y6P7
uniprot id: A0A8B8TQS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: focal adhesion

419612:CHRNB2
gene id: 419612:CHRNB2
uniprot id: A0A8B6YA03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:IQSEC3
gene id: 419612:IQSEC3
uniprot id: A0A8B8SGF5
names: Similarity
messages: Belongs to the BRAG family.

419612:C5AR2
gene id: 419612:C5AR2
uniprot id: A0A8B8TH71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

419612:LOC102510789
gene id: 419612:LOC102510789
uniprot id: S9XN96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

419612:LOC102505680
gene id: 419612:LOC102505680
uniprot id: A0A8B8TWS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:FARSA
gene id: 419612:FARSA
uniprot id: A0A8B6Y8N6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

419612:SERPINA10
gene id: 419612:SERPINA10
uniprot id: S9WZQ4
names: Similarity
messages: Belongs to the serpin family.

419612:PHOSPHO2
gene id: 419612:PHOSPHO2
uniprot id: A0A8B6YEY6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

419612:IPO8
gene id: 419612:IPO8
uniprot id: A0A8B8SFY5
names: Subcellular Location Annotation
messages: Cytoplasm

419612:LOC102504432
gene id: 419612:LOC102504432
uniprot id: A0A8B6Y6Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC106729839
gene id: 419612:LOC106729839
uniprot id: A0A8B8TGT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

419612:DDX43
gene id: 419612:DDX43
uniprot id: A0A8B8RE04
names: Similarity
messages: Belongs to the DEAD box helicase family.

419612:GEM
gene id: 419612:GEM
uniprot id: A0A8B6YLY3
uniprot id: S9WBC0
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

419612:PRDM15
gene id: 419612:PRDM15
uniprot id: A0A8B8RGG2
uniprot id: A0A8B8RIU2
names: Subcellular Location Annotation
messages: Nucleus

419612:LOC102515565
gene id: 419612:LOC102515565
uniprot id: A0A8B6YC77
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:BPGM
gene id: 419612:BPGM
uniprot id: S9WCD9
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

419612:LOC116660960
gene id: 419612:LOC116660960
uniprot id: A0A8B8SCP4
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

419612:PPAT
gene id: 419612:PPAT
uniprot id: A0A8B6Y8V7
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

419612:ZDHHC22
gene id: 419612:ZDHHC22
uniprot id: S9WZ32
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

419612:BEST2
gene id: 419612:BEST2
uniprot id: A0A8B8RTY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

419612:LOC116659847
gene id: 419612:LOC116659847
uniprot id: A0A8B8S0Q4
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

419612:LOC116662145
gene id: 419612:LOC116662145
uniprot id: A0A8B8SNC3
names: Similarity
messages: Belongs to the TEX13 family.

419612:GNRHR
gene id: 419612:GNRHR
uniprot id: A0A8B6YG17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.

419612:LOC102522989
gene id: 419612:LOC102522989
uniprot id: A0A8B8TSJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

419612:DYNC2LI1
gene id: 419612:DYNC2LI1
uniprot id: A0A8B6YHP4
uniprot id: A0A8B7KDD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

419612:DGCR2
gene id: 419612:DGCR2
uniprot id: A0A8B8SBZ6
uniprot id: A0A8B8SDA5
uniprot id: A0A8B8SEH3
uniprot id: A0A8B8SEH6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:MEP1B
gene id: 419612:MEP1B
uniprot id: A0A8B8S077
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:ATP6V0E1
gene id: 419612:ATP6V0E1
uniprot id: A0A8B8RXS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

419612:YIPF6
gene id: 419612:YIPF6
uniprot id: A0A8B8SPA4
uniprot id: A0A8B8SQ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

419612:RHBG
gene id: 419612:RHBG
uniprot id: A0A8B6YAE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

419612:LOC102513965
gene id: 419612:LOC102513965
uniprot id: A0A8B6YBD6
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

419612:CEP290
gene id: 419612:CEP290
uniprot id: A0A8B8U5F3
names: Subcellular Location Annotation
messages: cilium basal body

419612:LOC102517857
gene id: 419612:LOC102517857
uniprot id: A0A8B8U142
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

419612:CD8B
gene id: 419612:CD8B
uniprot id: A0A8B6YFN2
names: Subcellular Location Annotation
messages: Membrane

419612:MVP
gene id: 419612:MVP
uniprot id: A0A8B6YCY4
uniprot id: A0A8B8RH01
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

419612:SOX11
gene id: 419612:SOX11
uniprot id: A0A8B8UE44
uniprot id: A0A8B8UFI3
names: Subcellular Location Annotation
messages: Nucleus

419612:GUCY2C
gene id: 419612:GUCY2C
uniprot id: A0A8B6YM82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

419612:LOC102504901
gene id: 419612:LOC102504901
uniprot id: A0A8B6YN89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:GRK7
gene id: 419612:GRK7
uniprot id: A0A8B6YPE3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

419612:DYDC2
gene id: 419612:DYDC2
uniprot id: A0A8B8TVU7
names: Similarity
messages: Belongs to the dpy-30 family.

419612:GPR12
gene id: 419612:GPR12
uniprot id: A0A8B8UC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

419612:FBXO32
gene id: 419612:FBXO32
uniprot id: A0A8B7K6L5
names: Subcellular Location Annotation
messages: Nucleus

419612:PUS7
gene id: 419612:PUS7
uniprot id: A0A8B8TCX0
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

419612:UBE2D1
gene id: 419612:UBE2D1
uniprot id: A0A8B8TYE3
uniprot id: A0A8B8TZQ4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

419612:TNFRSF9
gene id: 419612:TNFRSF9
uniprot id: A0A8B6YPA6
uniprot id: A0A8B8U8T4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:PTER
gene id: 419612:PTER
uniprot id: A0A8B7K449
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:SNCG
gene id: 419612:SNCG
uniprot id: A0A8B7K743
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.
messages: spindle

419612:LOC102512831
gene id: 419612:LOC102512831
uniprot id: A0A8B6YNC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:RBPJL
gene id: 419612:RBPJL
uniprot id: A0A8B8RGN4
uniprot id: A0A8B8RGN8
uniprot id: A0A8B8RGW1
uniprot id: A0A8B8RIL9
uniprot id: A0A8B8RJ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

419612:RPN2
gene id: 419612:RPN2
uniprot id: A0A8B8RJN1
uniprot id: A0A8B8RJZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

419612:NME3
gene id: 419612:NME3
uniprot id: A0A8B8RG22
names: Similarity
messages: Belongs to the NDK family.

419612:TRPC5
gene id: 419612:TRPC5
uniprot id: A0A8B6YMY3
names: Subcellular Location Annotation
messages: Membrane

419612:PVALB
gene id: 419612:PVALB
uniprot id: S9XNN3
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

419612:FOXB2
gene id: 419612:FOXB2
uniprot id: A0A8B8SVC6
names: Subcellular Location Annotation
messages: Nucleus

419612:LGR6
gene id: 419612:LGR6
uniprot id: A0A8B8RXX0
uniprot id: A0A8B8RXY2
uniprot id: A0A8B8RZB4
uniprot id: A0A8B8RZL6
names: Subcellular Location Annotation
messages: Membrane

419612:PNP
gene id: 419612:PNP
uniprot id: S9WKC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

419612:SLC1A3
gene id: 419612:SLC1A3
uniprot id: A0A8B6YFR3
uniprot id: A0A8B8SB20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

419612:CHRNB1
gene id: 419612:CHRNB1
uniprot id: A0A8B8UJ99
uniprot id: A0A8B8UKA7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

419612:SULT6B1
gene id: 419612:SULT6B1
uniprot id: A0A8B6YMR9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

419612:LOC102507386
gene id: 419612:LOC102507386
uniprot id: A0A8B6YQ98
uniprot id: A0A8B8TTB6
names: Subcellular Location Annotation
messages: Membrane

419612:ACTN1
gene id: 419612:ACTN1
uniprot id: A0A8B8T7A9
uniprot id: A0A8B8T7W3
uniprot id: A0A8B8T879
names: Similarity
messages: Belongs to the alpha-actinin family.

419612:LOC102521062
gene id: 419612:LOC102521062
uniprot id: T0NQ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:HASPIN
gene id: 419612:HASPIN
uniprot id: A0A8B6Y4I0
names: Subcellular Location Annotation
messages: Chromosome

419612:SELP
gene id: 419612:SELP
uniprot id: A0A8B8RPF1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:BABAM2
gene id: 419612:BABAM2
uniprot id: A0A8B8UEX6
uniprot id: A0A8B8UEY1
uniprot id: A0A8B8UEY5
uniprot id: A0A8B8UEZ0
uniprot id: A0A8B8UFN6
uniprot id: A0A8B8UFQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

419612:SLC2A2
gene id: 419612:SLC2A2
uniprot id: A0A8B6YIP7
uniprot id: A0A8B7KC51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

419612:LOC102505620
gene id: 419612:LOC102505620
uniprot id: A0A8B6YE17
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SLC37A1
gene id: 419612:SLC37A1
uniprot id: A0A8B8RA63
uniprot id: A0A8B8RAP6
uniprot id: A0A8B8RD06
uniprot id: A0A8B8RD51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

419612:SERPINA4
gene id: 419612:SERPINA4
uniprot id: S9Y2L9
names: Similarity
messages: Belongs to the serpin family.

419612:IMMT
gene id: 419612:IMMT
uniprot id: A0A8B8S5N0
uniprot id: A0A8B8S6Z7
uniprot id: A0A8B8S752
uniprot id: A0A8B8S7Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

419612:LOC106729931
gene id: 419612:LOC106729931
uniprot id: A0A8B8TGE3
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

419612:ARL5C
gene id: 419612:ARL5C
uniprot id: A0A8B7K6P6
uniprot id: S9XG42
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

419612:RBM8A
gene id: 419612:RBM8A
uniprot id: A0A8B6Y4N9
uniprot id: S9YRT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

419612:RPL12
gene id: 419612:RPL12
uniprot id: A0A8B6YCS3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

419612:LOC102524572
gene id: 419612:LOC102524572
uniprot id: S9WH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

419612:PLA2G4E
gene id: 419612:PLA2G4E
uniprot id: A0A8B6YA67
uniprot id: A0A8B8T4Y3
uniprot id: A0A8B8T585
uniprot id: A0A8B8T5S5
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

419612:INHA
gene id: 419612:INHA
uniprot id: A0A8B6YHH8
uniprot id: A0A8B7KBC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

419612:NXT2
gene id: 419612:NXT2
uniprot id: A0A8B8SK84
uniprot id: A0A8B8SLM7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

419612:MANF
gene id: 419612:MANF
uniprot id: A0A8B8RAM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

419612:DCBLD2
gene id: 419612:DCBLD2
uniprot id: A0A8B6YDE9
uniprot id: A0A8B8TTY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:STX18
gene id: 419612:STX18
uniprot id: A0A8B8U5A3
uniprot id: A0A8B8U5A9
uniprot id: A0A8B8U6F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

419612:THNSL2
gene id: 419612:THNSL2
uniprot id: A0A8B8S5E0
uniprot id: A0A8B8S6W1
uniprot id: A0A8B8S7F3
names: Similarity
messages: Belongs to the threonine synthase family.

419612:RPS13
gene id: 419612:RPS13
uniprot id: A0A8B6YR55
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

419612:SEPTIN2
gene id: 419612:SEPTIN2
uniprot id: A0A8B8T3T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium membrane
messages: flagellum
messages: spindle

419612:NDUFC2
gene id: 419612:NDUFC2
uniprot id: A0A8B6YLV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

419612:ITM2A
gene id: 419612:ITM2A
uniprot id: A0A8B6YP65
uniprot id: A0A8B7KG62
uniprot id: A0A8B8SLL0
uniprot id: A0A8B8SMN8
uniprot id: A0A8B8SNT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

419612:LOC102507342
gene id: 419612:LOC102507342
uniprot id: A0A8B6YGJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:DENND6B
gene id: 419612:DENND6B
uniprot id: A0A8B8U1P1
uniprot id: A0A8B8U258
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

419612:KCNV1
gene id: 419612:KCNV1
uniprot id: A0A8B8S0E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

419612:DLX2
gene id: 419612:DLX2
uniprot id: A0A8B8SZX8
uniprot id: A0A8B8T0W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

419612:GGACT
gene id: 419612:GGACT
uniprot id: A0A8B8UDF3
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.

419612:TGM3
gene id: 419612:TGM3
uniprot id: A0A8B6YLL8
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

419612:GMFG
gene id: 419612:GMFG
uniprot id: A0A8B6Y926
uniprot id: A0A8B7K5H2
uniprot id: A0A8B7K5T4
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

419612:LOC102516460
gene id: 419612:LOC102516460
uniprot id: A0A8B6YH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

419612:EXO1
gene id: 419612:EXO1
uniprot id: A0A8B6YG53
uniprot id: A0A8B7KAJ1
uniprot id: A0A8B8RWS2
uniprot id: A0A8B8RY78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

419612:TMEM199
gene id: 419612:TMEM199
uniprot id: A0A8B6YFK7
uniprot id: A0A8B7KA16
uniprot id: A0A8B7KAR0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

419612:CDC42SE1
gene id: 419612:CDC42SE1
uniprot id: A0A8B8RR73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

419612:FADS3
gene id: 419612:FADS3
uniprot id: A0A8B6Y558
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

419612:PLK1
gene id: 419612:PLK1
uniprot id: S9XH61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Midbody
messages: Nucleus
messages: centrosome

419612:PIANP
gene id: 419612:PIANP
uniprot id: A0A8B8SG02
names: Subcellular Location Annotation
messages: Membrane

419612:NUCB1
gene id: 419612:NUCB1
uniprot id: A0A8B7KBF8
uniprot id: S9YNY9
names: Similarity
messages: Belongs to the nucleobindin family.

419612:LOC102522118
gene id: 419612:LOC102522118
uniprot id: S9WBB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

419612:TMEM35B
gene id: 419612:TMEM35B
uniprot id: A0A8B8UCC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

419612:CMTM2
gene id: 419612:CMTM2
uniprot id: A0A8B6YC66
names: Subcellular Location Annotation
messages: Membrane

419612:TAS2R39
gene id: 419612:TAS2R39
uniprot id: A0A8B7KAD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

419612:SLC17A9
gene id: 419612:SLC17A9
uniprot id: A0A8B8RHK3
names: Subcellular Location Annotation
messages: Membrane

419612:MYO15A
gene id: 419612:MYO15A
uniprot id: A0A8B8UKB4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

419612:MRPS7
gene id: 419612:MRPS7
uniprot id: A0A8B7K4N2
uniprot id: T0NP15
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

419612:LOC102514399
gene id: 419612:LOC102514399
uniprot id: A0A8B6YIU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

419612:SLC35A5
gene id: 419612:SLC35A5
uniprot id: A0A8B6Y6R6
uniprot id: A0A8B7KFA8
uniprot id: A0A8B8SYD4
uniprot id: A0A8B8SYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

419612:CYRIB
gene id: 419612:CYRIB
uniprot id: A0A8B8S1F3
uniprot id: A0A8B8S2R5
uniprot id: A0A8B8S309
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

419612:SUPT20H
gene id: 419612:SUPT20H
uniprot id: A0A8B8UC48
uniprot id: A0A8B8UC49
uniprot id: A0A8B8UC52
uniprot id: A0A8B8UCU7
uniprot id: A0A8B8UCV2
uniprot id: A0A8B8UCY7
uniprot id: A0A8B8UDG4
uniprot id: A0A8B8UDG9
names: Similarity
messages: Belongs to the SPT20 family.

419612:LOC102519958
gene id: 419612:LOC102519958
uniprot id: A0A8B6YL06
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:CAPN10
gene id: 419612:CAPN10
uniprot id: A0A8B8T367
uniprot id: A0A8B8T3K2
uniprot id: A0A8B8T3N1
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:C18H16orf91
gene id: 419612:C18H16orf91
uniprot id: A0A8B7KCR9
names: Similarity
messages: Belongs to the UQCC4 family.

419612:VSX2
gene id: 419612:VSX2
uniprot id: A0A8B8T989
names: Subcellular Location Annotation
messages: Nucleus

419612:EPHA3
gene id: 419612:EPHA3
uniprot id: A0A8B8SUC9
uniprot id: A0A8B8SUQ9
uniprot id: A0A8B8SVG5
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102509393
gene id: 419612:LOC102509393
uniprot id: A0A8B7KI13
names: Similarity
messages: Belongs to the actin family.

419612:LOC106730101
gene id: 419612:LOC106730101
uniprot id: A0A8B7KCT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

419612:TNMD
gene id: 419612:TNMD
uniprot id: A0A8B6YNJ1
uniprot id: A0A8B7KGV7
names: Similarity
messages: Belongs to the chondromodulin-1 family.

419612:CHST1
gene id: 419612:CHST1
uniprot id: A0A8B8TQ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

419612:RAP2C
gene id: 419612:RAP2C
uniprot id: A0A8B8SJP0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

419612:SEMA4C
gene id: 419612:SEMA4C
uniprot id: A0A8B8S5K3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:VCL
gene id: 419612:VCL
uniprot id: A0A8B8TYR8
uniprot id: A0A8B8TYR9
uniprot id: A0A8B8TYV6
uniprot id: A0A8B8U033
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: podosome

419612:HAX1
gene id: 419612:HAX1
uniprot id: A0A8B6Y947
uniprot id: A0A8B8RQ63
names: Function
names: Similarity
messages: Belongs to the HAX1 family.
messages: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.

419612:NDUFA3
gene id: 419612:NDUFA3
uniprot id: A0A8B8TNL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

419612:LOC106730949
gene id: 419612:LOC106730949
uniprot id: A0A8B8TVJ6
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:RAB39B
gene id: 419612:RAB39B
uniprot id: S9W9V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

419612:ATG4A
gene id: 419612:ATG4A
uniprot id: A0A8B6YN39
uniprot id: A0A8B8SN52
uniprot id: A0A8B8SN55
uniprot id: A0A8B8SQC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

419612:YTHDF3
gene id: 419612:YTHDF3
uniprot id: A0A8B8S7B4
uniprot id: A0A8B8S8L1
uniprot id: A0A8B8S8S1
uniprot id: A0A8B8S9I0
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

419612:MEX3A
gene id: 419612:MEX3A
uniprot id: A0A8B6YTC6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

419612:GCDH
gene id: 419612:GCDH
uniprot id: A0A8B6Y711
uniprot id: A0A8B8RVS2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

419612:DZIP3
gene id: 419612:DZIP3
uniprot id: A0A8B7KH18
uniprot id: A0A8B8SWT3
uniprot id: A0A8B8SXA2
names: Subcellular Location Annotation
messages: Cytoplasm

419612:HSP90AA1
gene id: 419612:HSP90AA1
uniprot id: A0A8B8T8I5
uniprot id: A0A8B8T906
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

419612:TNS1
gene id: 419612:TNS1
uniprot id: A0A8B8T1E7
uniprot id: A0A8B8T1E8
uniprot id: A0A8B8T1F2
uniprot id: A0A8B8T1F3
uniprot id: A0A8B8T1T5
uniprot id: A0A8B8T1U4
uniprot id: A0A8B8T1Y9
uniprot id: A0A8B8T1Z4
uniprot id: A0A8B8T2A9
uniprot id: A0A8B8T2B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

419612:HNRNPR
gene id: 419612:HNRNPR
uniprot id: A0A8B8U9Q6
uniprot id: A0A8B8U9R7
uniprot id: A0A8B8UAI5
uniprot id: A0A8B8UAN4
names: Subcellular Location Annotation
messages: Cytoplasm

419612:COPZ2
gene id: 419612:COPZ2
uniprot id: A0A8B8R921
uniprot id: A0A8B8R9P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

419612:CIBAR2
gene id: 419612:CIBAR2
uniprot id: A0A8B8RQZ9
uniprot id: A0A8B8RR04
uniprot id: A0A8B8RRM0
uniprot id: A0A8B8RSN5
uniprot id: A0A8B8RSP0
uniprot id: A0A8B8RSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

419612:PCNT
gene id: 419612:PCNT
uniprot id: A0A8B8TGQ2
uniprot id: A0A8B8TGW5
uniprot id: A0A8B8TH42
uniprot id: A0A8B8THD0
uniprot id: A0A8B8THI2
uniprot id: A0A8B8THQ7
uniprot id: A0A8B8THX4
uniprot id: A0A8B8TI36
uniprot id: A0A8B8TI81
uniprot id: A0A8B8TIF0
uniprot id: A0A8B8TIP6
uniprot id: A0A8B8TIU5
names: Subcellular Location Annotation
messages: centrosome

419612:SMAGP
gene id: 419612:SMAGP
uniprot id: A0A8B8U3L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAGP family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

419612:MICAL3
gene id: 419612:MICAL3
uniprot id: A0A8B8SF80
uniprot id: A0A8B8SF89
uniprot id: A0A8B8SF93
uniprot id: A0A8B8SF97
uniprot id: A0A8B8SFA1
uniprot id: A0A8B8SFA3
uniprot id: A0A8B8SFA6
uniprot id: A0A8B8SFB0
uniprot id: A0A8B8SFB2
uniprot id: A0A8B8SFB8
uniprot id: A0A8B8SFB9
uniprot id: A0A8B8SFC3
uniprot id: A0A8B8SFC6
uniprot id: A0A8B8SGE8
uniprot id: A0A8B8SGF4
uniprot id: A0A8B8SGG0
uniprot id: A0A8B8SGH1
uniprot id: A0A8B8SGH7
uniprot id: A0A8B8SGI4
uniprot id: A0A8B8SGJ0
uniprot id: A0A8B8SGJ8
uniprot id: A0A8B8SGK4
uniprot id: A0A8B8SHU0
uniprot id: A0A8B8SHU8
uniprot id: A0A8B8SHV7
uniprot id: A0A8B8SHW4
uniprot id: A0A8B8SHX1
uniprot id: A0A8B8SHX9
uniprot id: A0A8B8SHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

419612:CKAP2L
gene id: 419612:CKAP2L
uniprot id: A0A8B6YEQ7
uniprot id: A0A8B8S7D9
names: Similarity
messages: Belongs to the CKAP2 family.

419612:ADD2
gene id: 419612:ADD2
uniprot id: A0A8B8UGF1
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

419612:CD9
gene id: 419612:CD9
uniprot id: A0A8B8SHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

419612:ISOC2
gene id: 419612:ISOC2
uniprot id: A0A8B7KBG2
names: Similarity
messages: Belongs to the isochorismatase family.

419612:ZNF496
gene id: 419612:ZNF496
uniprot id: A0A8B8SSP1
uniprot id: A0A8B8SUA3
names: Subcellular Location Annotation
messages: Nucleus

419612:MRPS31
gene id: 419612:MRPS31
uniprot id: A0A8B6YAW6
uniprot id: A0A8B7K6Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

419612:AP1G2
gene id: 419612:AP1G2
uniprot id: S9YRP1
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

419612:CACNG3
gene id: 419612:CACNG3
uniprot id: A0A8B6YPH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

419612:LOC106731055
gene id: 419612:LOC106731055
uniprot id: A0A8B8TVC9
uniprot id: A0A8B8TVD0
uniprot id: A0A8B8TWN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

419612:LOC102515176
gene id: 419612:LOC102515176
uniprot id: A0A8B8TS37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:TMEM216
gene id: 419612:TMEM216
uniprot id: A0A8B6Y548
uniprot id: A0A8B6Y5Q6
uniprot id: A0A8B8TU70
names: Subcellular Location Annotation
messages: Membrane

419612:RARB
gene id: 419612:RARB
uniprot id: A0A8B6Y989
uniprot id: A0A8B6YBQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

419612:CHSY3
gene id: 419612:CHSY3
uniprot id: A0A8B6YF43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

419612:E2F7
gene id: 419612:E2F7
uniprot id: A0A8B8U4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

419612:LOC102511156
gene id: 419612:LOC102511156
uniprot id: A0A8B6YFF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LTB4R
gene id: 419612:LTB4R
uniprot id: A0A8B8T5Z0
uniprot id: A0A8B8T6L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

419612:LOC102508864
gene id: 419612:LOC102508864
uniprot id: S9WY97
names: Subcellular Location Annotation
messages: Membrane

419612:GRB7
gene id: 419612:GRB7
uniprot id: A0A8B6Y843
uniprot id: A0A8B8R754
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

419612:POLE
gene id: 419612:POLE
uniprot id: A0A8B8SC73
uniprot id: A0A8B8SEQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

419612:MRPS33
gene id: 419612:MRPS33
uniprot id: S9XZB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

419612:NDEL1
gene id: 419612:NDEL1
uniprot id: A0A8B6Y8K6
uniprot id: A0A8B8UJS5
uniprot id: A0A8B8UJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: kinetochore
messages: spindle

419612:TNS4
gene id: 419612:TNS4
uniprot id: A0A8B6YJE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

419612:CHST7
gene id: 419612:CHST7
uniprot id: A0A8B8SL78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

419612:RNFT1
gene id: 419612:RNFT1
uniprot id: A0A8B6YIU0
uniprot id: A0A8B7KCK0
uniprot id: A0A8B7KDB8
names: Subcellular Location Annotation
messages: Membrane

419612:LOC102511861
gene id: 419612:LOC102511861
uniprot id: S9WEY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:SPPL2A
gene id: 419612:SPPL2A
uniprot id: A0A8B8T4A1
uniprot id: A0A8B8T4B0
uniprot id: A0A8B8T4M1
uniprot id: A0A8B8T539
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

419612:WDPCP
gene id: 419612:WDPCP
uniprot id: A0A8B7KEI8
uniprot id: A0A8B7KEK4
uniprot id: A0A8B7KFU5
uniprot id: A0A8B8UG39
uniprot id: A0A8B8UGT7
uniprot id: A0A8B8UHH3
uniprot id: A0A8B8UHH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

419612:LOC116662259
gene id: 419612:LOC116662259
uniprot id: A0A8B8SQD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm

419612:LOC102512182
gene id: 419612:LOC102512182
uniprot id: S9XLE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

419612:VCAN
gene id: 419612:VCAN
uniprot id: A0A8B6Y9S6
uniprot id: A0A8B6YB90
uniprot id: A0A8B6YDU2
uniprot id: A0A8B8SPF9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

419612:TTC21A
gene id: 419612:TTC21A
uniprot id: A0A8B7K4Q2
names: Similarity
messages: Belongs to the TTC21 family.

419612:APOOL
gene id: 419612:APOOL
uniprot id: A0A8B8SJL2
uniprot id: A0A8B8SJL6
uniprot id: A0A8B8SKP9
uniprot id: A0A8B8SL13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

419612:TUFM
gene id: 419612:TUFM
uniprot id: A0A8B8RES2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

419612:LYPLA1
gene id: 419612:LYPLA1
uniprot id: A0A8B8S768
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

419612:TERF2IP
gene id: 419612:TERF2IP
uniprot id: A0A8B6YPS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

419612:CDT1
gene id: 419612:CDT1
uniprot id: A0A8B8RS03
names: Similarity
messages: Belongs to the Cdt1 family.

419612:PITX3
gene id: 419612:PITX3
uniprot id: A0A8B8TX96
uniprot id: A0A8B8TYM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

419612:TRAPPC2L
gene id: 419612:TRAPPC2L
uniprot id: A0A8B8RRC7
uniprot id: A0A8B8RT16
uniprot id: A0A8B8RTC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network
messages: perinuclear region

419612:INSL5
gene id: 419612:INSL5
uniprot id: A0A8B6YMI1
uniprot id: A0A8B8U8P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

419612:LOC102516399
gene id: 419612:LOC102516399
uniprot id: S9XKH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

419612:TAP2
gene id: 419612:TAP2
uniprot id: A0A8B6YFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
messages: Membrane

419612:SFXN3
gene id: 419612:SFXN3
uniprot id: A0A8B7K963
uniprot id: A0A8B7K9E0
uniprot id: A0A8B7KAX7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

419612:GCNT3
gene id: 419612:GCNT3
uniprot id: A0A8B8T4N4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

419612:TMOD4
gene id: 419612:TMOD4
uniprot id: A0A8B7KC03
names: Subcellular Location Annotation
messages: cytoskeleton

419612:LOC102509343
gene id: 419612:LOC102509343
uniprot id: A0A8B6YGK4
names: Subcellular Location Annotation
messages: Membrane

419612:CADM1
gene id: 419612:CADM1
uniprot id: A0A8B8SDW6
uniprot id: A0A8B8SDX6
uniprot id: A0A8B8SF37
uniprot id: A0A8B8SF79
names: Similarity
messages: Belongs to the nectin family.

419612:LOC116661684
gene id: 419612:LOC116661684
uniprot id: A0A8B8SIM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102519637
gene id: 419612:LOC102519637
uniprot id: A0A8B6YCM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:BRINP2
gene id: 419612:BRINP2
uniprot id: A0A8B8RQF5
names: Similarity
messages: Belongs to the BRINP family.

419612:DPP3
gene id: 419612:DPP3
uniprot id: A0A8B6YAR3
uniprot id: A0A8B6YB30
uniprot id: A0A8B7K6W7
uniprot id: A0A8B7K8R7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

419612:SH3RF2
gene id: 419612:SH3RF2
uniprot id: A0A8B8SS06
uniprot id: A0A8B8SSN3
names: Similarity
messages: Belongs to the SH3RF family.

419612:TNK2
gene id: 419612:TNK2
uniprot id: A0A8B8T4H3
uniprot id: A0A8B8T4I5
uniprot id: A0A8B8T4X2
uniprot id: A0A8B8T4Z0
uniprot id: A0A8B8T4Z1
uniprot id: A0A8B8T4Z4
uniprot id: A0A8B8T507
uniprot id: A0A8B8T515
uniprot id: A0A8B8T519
uniprot id: A0A8B8T522
uniprot id: A0A8B8T523
uniprot id: A0A8B8T534
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus

419612:DDAH2
gene id: 419612:DDAH2
uniprot id: A0A8B8RKW5
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

419612:TNP1
gene id: 419612:TNP1
uniprot id: A0A8B6YHQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear transition protein 1 family.
messages: Chromosome
messages: Nucleus

419612:KIF26A
gene id: 419612:KIF26A
uniprot id: A0A8B8T9D4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

419612:NFIX
gene id: 419612:NFIX
uniprot id: A0A8B6Y7H2
uniprot id: A0A8B7K3K7
uniprot id: A0A8B7K3X3
uniprot id: A0A8B7K433
uniprot id: A0A8B7K624
uniprot id: A0A8B8RTV9
uniprot id: A0A8B8RUX4
uniprot id: A0A8B8RVG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

419612:SLC24A4
gene id: 419612:SLC24A4
uniprot id: A0A8B6YEV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

419612:RPLP0
gene id: 419612:RPLP0
uniprot id: A0A8B6YMP1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

419612:LOC116667534
gene id: 419612:LOC116667534
uniprot id: A0A8B8U380
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

419612:RPL36AL
gene id: 419612:RPL36AL
uniprot id: A0A8B6YMX0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

419612:S100A4
gene id: 419612:S100A4
uniprot id: S9X7H9
names: Similarity
messages: Belongs to the S-100 family.

419612:MMS19
gene id: 419612:MMS19
uniprot id: A0A8B7KA76
uniprot id: A0A8B8TXL6
uniprot id: A0A8B8TYN0
uniprot id: A0A8B8TYY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

419612:LOC102507086
gene id: 419612:LOC102507086
uniprot id: A0A8B7KE10
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

419612:LOC102503614
gene id: 419612:LOC102503614
uniprot id: A0A8B7KCZ9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:LOC102522718
gene id: 419612:LOC102522718
uniprot id: A0A8B8U8J6
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

419612:PLXNB2
gene id: 419612:PLXNB2
uniprot id: A0A8B8U1M4
uniprot id: A0A8B8U1N1
uniprot id: A0A8B8U2X2
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

419612:NAP1L1
gene id: 419612:NAP1L1
uniprot id: A0A8B8U4W1
uniprot id: A0A8B8U5P5
uniprot id: A0A8B8U5T6
uniprot id: A0A8B8U608
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

419612:LOC102520097
gene id: 419612:LOC102520097
uniprot id: A0A8B8RWC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:S100A12
gene id: 419612:S100A12
uniprot id: S9X7H4
names: Similarity
messages: Belongs to the S-100 family.

419612:NID1
gene id: 419612:NID1
uniprot id: A0A8B8TZQ1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

419612:HNRNPAB
gene id: 419612:HNRNPAB
uniprot id: A0A8B8RSA0
uniprot id: A0A8B8RT42
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

419612:LOC102517348
gene id: 419612:LOC102517348
uniprot id: A0A8B6YPX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:XDH
gene id: 419612:XDH
uniprot id: A0A8B6YFB7
uniprot id: A0A8B8UF22
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Homodimer. Interacts with BTN1A1.
messages: Peroxisome

419612:SCGB2A2
gene id: 419612:SCGB2A2
uniprot id: A0A8B7K6T7
names: Subcellular Location Annotation
messages: Secreted

419612:DSG4
gene id: 419612:DSG4
uniprot id: A0A8B7KBJ3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

419612:LOC102513073
gene id: 419612:LOC102513073
uniprot id: A0A8B7KGC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

419612:PAQR5
gene id: 419612:PAQR5
uniprot id: A0A8B8S656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

419612:PDGFB
gene id: 419612:PDGFB
uniprot id: T0MCK3
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

419612:LOC116664291
gene id: 419612:LOC116664291
uniprot id: A0A8B8T7J4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.