415426:HBUT RS06580
gene id: 415426:HBUT_RS06580
uniprot id: A2BM80
names: Similarity
messages: Belongs to the ZPR1 family.

415426:HBUT RS02025
gene id: 415426:HBUT_RS02025
uniprot id: A2BJU4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

415426:HBUT RS03965
gene id: 415426:HBUT_RS03965
uniprot id: A2BKU7
names: Similarity
messages: Belongs to the HupF/HypC family.

415426:HBUT RS00565
gene id: 415426:HBUT_RS00565
uniprot id: A2BJ23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

415426:HBUT RS02070
gene id: 415426:HBUT_RS02070
uniprot id: A2BJV3
names: Caution
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

415426:HBUT RS06895
gene id: 415426:HBUT_RS06895
uniprot id: A2BMD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

415426:HBUT RS04880
gene id: 415426:HBUT_RS04880
uniprot id: A2BLB7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

415426:HBUT RS00955
gene id: 415426:HBUT_RS00955
uniprot id: A2BJ97
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS03485
gene id: 415426:HBUT_RS03485
uniprot id: A2BKL6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

415426:HBUT RS00185
gene id: 415426:HBUT_RS00185
uniprot id: A2BIS3
names: Similarity
messages: Belongs to the Ahb/Nir family.

415426:HBUT RS03590
gene id: 415426:HBUT_RS03590
uniprot id: A2BKN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

415426:HBUT RS02280
gene id: 415426:HBUT_RS02280
uniprot id: A2BJZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

415426:HBUT RS06910
gene id: 415426:HBUT_RS06910
uniprot id: A2BME0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

415426:HBUT RS05855
gene id: 415426:HBUT_RS05855
uniprot id: A2BLV2
names: Similarity
messages: Belongs to the UPF0047 family.

415426:HBUT RS03970
gene id: 415426:HBUT_RS03970
uniprot id: A2BKU8
names: Similarity
messages: Belongs to the HypD family.

415426:HBUT RS04380
gene id: 415426:HBUT_RS04380
uniprot id: A2BL24
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

415426:HBUT RS08395
gene id: 415426:HBUT_RS08395
uniprot id: A2BN63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

415426:HBUT RS01965
gene id: 415426:HBUT_RS01965
uniprot id: A2BJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

415426:HBUT RS08510
gene id: 415426:HBUT_RS08510
uniprot id: A2BN82
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

415426:HBUT RS02740
gene id: 415426:HBUT_RS02740
uniprot id: A2BK76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

415426:HBUT RS08410
gene id: 415426:HBUT_RS08410
uniprot id: A2BN65
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

415426:HBUT RS07445
gene id: 415426:HBUT_RS07445
uniprot id: A2BMN8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

415426:HBUT RS04135
gene id: 415426:HBUT_RS04135
uniprot id: A2BKY0
names: Similarity
messages: Belongs to the Nth/MutY family.

415426:HBUT RS00290
gene id: 415426:HBUT_RS00290
uniprot id: A2BIX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high-temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to norspermidine, spermidine and norspermine to yield norspermine, thermospermine and caldopentamine, respectively. It can also synthesize sym-norspermidine (bis(3-aminopropyl)amine) from 1,3-diaminopropane with a very low activity. The biosynthesis of caldohexamine and caldoheptamine from caldopentamine has been also observed.

415426:HBUT RS06865
gene id: 415426:HBUT_RS06865
uniprot id: A2BMD1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

415426:HBUT RS01745
gene id: 415426:HBUT_RS01745
uniprot id: A2BJP2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

415426:HBUT RS05390
gene id: 415426:HBUT_RS05390
uniprot id: A2BLL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

415426:HBUT RS07930
gene id: 415426:HBUT_RS07930
uniprot id: A2BMX5
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

415426:HBUT RS01840
gene id: 415426:HBUT_RS01840
uniprot id: A2BJR2
names: Similarity
messages: Belongs to the AOR/FOR family.

415426:HBUT RS04820
gene id: 415426:HBUT_RS04820
uniprot id: A2BLA5
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

415426:HBUT RS06770
gene id: 415426:HBUT_RS06770
uniprot id: A2BMB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

415426:HBUT RS08335
gene id: 415426:HBUT_RS08335
uniprot id: A2BN51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

415426:HBUT RS08360
gene id: 415426:HBUT_RS08360
uniprot id: A2BN56
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

415426:HBUT RS02245
gene id: 415426:HBUT_RS02245
uniprot id: A2BJY6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

415426:HBUT RS05775
gene id: 415426:HBUT_RS05775
uniprot id: A2BLU0
names: Similarity
messages: Belongs to the UPF0282 family.

415426:HBUT RS03870
gene id: 415426:HBUT_RS03870
uniprot id: A2BKT0
names: Similarity
messages: Belongs to the AOR/FOR family.

415426:HBUT RS01625
gene id: 415426:HBUT_RS01625
uniprot id: A2BJL9
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS02975
gene id: 415426:HBUT_RS02975
uniprot id: A2BKC3
names: Function
messages: Probably involved in the biogenesis of the ribosome.

415426:HBUT RS01055
gene id: 415426:HBUT_RS01055
uniprot id: A2BJB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

415426:HBUT RS00275
gene id: 415426:HBUT_RS00275
uniprot id: A2BIX1
names: Caution
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

415426:HBUT RS06830
gene id: 415426:HBUT_RS06830
uniprot id: A2BMC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

415426:HBUT RS01710
gene id: 415426:HBUT_RS01710
uniprot id: A2BJN5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

415426:HBUT RS02475
gene id: 415426:HBUT_RS02475
uniprot id: A2BK27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

415426:HBUT RS00235
gene id: 415426:HBUT_RS00235
uniprot id: A2BIW3
names: Similarity
messages: Belongs to the UPF0111 family.

415426:HBUT RS08200
gene id: 415426:HBUT_RS08200
uniprot id: A2BN26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm
messages: Homodimer.

415426:HBUT RS07420
gene id: 415426:HBUT_RS07420
uniprot id: A2BMN3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

415426:HBUT RS05495
gene id: 415426:HBUT_RS05495
uniprot id: A2BLN4
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

415426:HBUT RS04395
gene id: 415426:HBUT_RS04395
uniprot id: A2BL27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

415426:HBUT RS06525
gene id: 415426:HBUT_RS06525
uniprot id: A2BM70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

415426:HBUT RS04945
gene id: 415426:HBUT_RS04945
uniprot id: A2BLD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

415426:HBUT RS02880
gene id: 415426:HBUT_RS02880
uniprot id: A2BKA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

415426:HBUT RS08575
gene id: 415426:HBUT_RS08575
uniprot id: A2BN93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

415426:HBUT RS01130
gene id: 415426:HBUT_RS01130
uniprot id: A2BJC9
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

415426:HBUT RS03865
gene id: 415426:HBUT_RS03865
uniprot id: A2BKS9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

415426:HBUT RS08195
gene id: 415426:HBUT_RS08195
uniprot id: A2BN25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

415426:HBUT RS01755
gene id: 415426:HBUT_RS01755
uniprot id: A2BJP4
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

415426:HBUT RS06725
gene id: 415426:HBUT_RS06725
uniprot id: A2BMA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

415426:HBUT RS01835
gene id: 415426:HBUT_RS01835
uniprot id: A2BJR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

415426:HBUT RS04665
gene id: 415426:HBUT_RS04665
uniprot id: A2BL75
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

415426:HBUT RS04530
gene id: 415426:HBUT_RS04530
uniprot id: A2BL51
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

415426:HBUT RS05665
gene id: 415426:HBUT_RS05665
uniprot id: A2BLR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

415426:HBUT RS06945
gene id: 415426:HBUT_RS06945
uniprot id: A2BME7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

415426:HBUT RS07170
gene id: 415426:HBUT_RS07170
uniprot id: A2BMI5
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

415426:HBUT RS08565
gene id: 415426:HBUT_RS08565
uniprot id: A2BN92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

415426:HBUT RS07250
gene id: 415426:HBUT_RS07250
uniprot id: A2BMK0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

415426:HBUT RS02600
gene id: 415426:HBUT_RS02600
uniprot id: A2BK50
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

415426:HBUT RS00780
gene id: 415426:HBUT_RS00780
uniprot id: A2BJ62
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

415426:HBUT RS08220
gene id: 415426:HBUT_RS08220
uniprot id: A2BN30
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

415426:HBUT RS08355
gene id: 415426:HBUT_RS08355
uniprot id: A2BN55
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

415426:HBUT RS00545
gene id: 415426:HBUT_RS00545
uniprot id: A2BJ19
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS07900
gene id: 415426:HBUT_RS07900
uniprot id: A2BMW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

415426:HBUT RS02820
gene id: 415426:HBUT_RS02820
uniprot id: A2BK92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

415426:HBUT RS06885
gene id: 415426:HBUT_RS06885
uniprot id: A2BMD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

415426:HBUT RS08205
gene id: 415426:HBUT_RS08205
uniprot id: A2BN27
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

415426:HBUT RS05945
gene id: 415426:HBUT_RS05945
uniprot id: A2BLW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

415426:HBUT RS04740
gene id: 415426:HBUT_RS04740
uniprot id: A2BL90
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS01725
gene id: 415426:HBUT_RS01725
uniprot id: A2BJN8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

415426:HBUT RS01060
gene id: 415426:HBUT_RS01060
uniprot id: A2BJB5
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

415426:HBUT RS08190
gene id: 415426:HBUT_RS08190
uniprot id: A2BN24
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

415426:HBUT RS08680
gene id: 415426:HBUT_RS08680
uniprot id: A2BNB3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

415426:HBUT RS08640
gene id: 415426:HBUT_RS08640
uniprot id: A2BNA5
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

415426:HBUT RS06575
gene id: 415426:HBUT_RS06575
uniprot id: A2BM79
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

415426:HBUT RS02230
gene id: 415426:HBUT_RS02230
uniprot id: A2BJY3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

415426:HBUT RS00255
gene id: 415426:HBUT_RS00255
uniprot id: A2BIW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm

415426:HBUT RS02840
gene id: 415426:HBUT_RS02840
uniprot id: A2BK96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

415426:HBUT RS04655
gene id: 415426:HBUT_RS04655
uniprot id: A2BL73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

415426:HBUT RS00790
gene id: 415426:HBUT_RS00790
uniprot id: A2BJ64
names: Similarity
messages: Belongs to the malic enzymes family.

415426:HBUT RS04980
gene id: 415426:HBUT_RS04980
uniprot id: A2BLD8
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

415426:HBUT RS04385
gene id: 415426:HBUT_RS04385
uniprot id: A2BL25
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

415426:HBUT RS05410
gene id: 415426:HBUT_RS05410
uniprot id: A2BLL9
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

415426:HBUT RS06880
gene id: 415426:HBUT_RS06880
uniprot id: A2BMD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

415426:HBUT RS01595
gene id: 415426:HBUT_RS01595
uniprot id: A2BJL3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

415426:HBUT RS04750
gene id: 415426:HBUT_RS04750
uniprot id: A2BL92
names: Subcellular Location Annotation
messages: Nucleus

415426:HBUT RS04720
gene id: 415426:HBUT_RS04720
uniprot id: A2BL86
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

415426:HBUT RS00925
gene id: 415426:HBUT_RS00925
uniprot id: A2BJ92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

415426:HBUT RS03755
gene id: 415426:HBUT_RS03755
uniprot id: A2BKR1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

415426:HBUT RS05305
gene id: 415426:HBUT_RS05305
uniprot id: A2BLK1
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

415426:HBUT RS05695
gene id: 415426:HBUT_RS05695
uniprot id: A2BLS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

415426:HBUT RS05430
gene id: 415426:HBUT_RS05430
uniprot id: A2BLM2
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

415426:HBUT RS06150
gene id: 415426:HBUT_RS06150
uniprot id: A2BM02
names: Similarity
messages: Belongs to the UPF0235 family.

415426:HBUT RS06265
gene id: 415426:HBUT_RS06265
uniprot id: A2BM25
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

415426:HBUT RS02445
gene id: 415426:HBUT_RS02445
uniprot id: A2BK22
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

415426:HBUT RS08345
gene id: 415426:HBUT_RS08345
uniprot id: A2BN53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

415426:HBUT RS02545
gene id: 415426:HBUT_RS02545
uniprot id: A2BK39
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

415426:HBUT RS04760
gene id: 415426:HBUT_RS04760
uniprot id: A2BL93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

415426:HBUT RS08390
gene id: 415426:HBUT_RS08390
uniprot id: A2BN62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

415426:HBUT RS00040
gene id: 415426:HBUT_RS00040
uniprot id: A2BIT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Membrane

415426:HBUT RS00075
gene id: 415426:HBUT_RS00075
uniprot id: A2BIT6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

415426:HBUT RS08695
gene id: 415426:HBUT_RS08695
uniprot id: A2BNB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

415426:HBUT RS00045
gene id: 415426:HBUT_RS00045
uniprot id: A2BIT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

415426:HBUT RS01275
gene id: 415426:HBUT_RS01275
uniprot id: A2BJF3
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS04870
gene id: 415426:HBUT_RS04870
uniprot id: A2BLB5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

415426:HBUT RS06980
gene id: 415426:HBUT_RS06980
uniprot id: A2BMF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

415426:HBUT RS06935
gene id: 415426:HBUT_RS06935
uniprot id: A2BME5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

415426:HBUT RS00115
gene id: 415426:HBUT_RS00115
uniprot id: A2BIU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

415426:HBUT RS00160
gene id: 415426:HBUT_RS00160
uniprot id: A2BIV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

415426:HBUT RS07765
gene id: 415426:HBUT_RS07765
uniprot id: A2BMU5
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS02435
gene id: 415426:HBUT_RS02435
uniprot id: A2BK20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

415426:HBUT RS02850
gene id: 415426:HBUT_RS02850
uniprot id: A2BK98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

415426:HBUT RS03285
gene id: 415426:HBUT_RS03285
uniprot id: A2BKH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

415426:HBUT RS08095
gene id: 415426:HBUT_RS08095
uniprot id: A2BN06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

415426:HBUT RS03475
gene id: 415426:HBUT_RS03475
uniprot id: A2BKL4
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

415426:HBUT RS08225
gene id: 415426:HBUT_RS08225
uniprot id: A2BN31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.

415426:HBUT RS02755
gene id: 415426:HBUT_RS02755
uniprot id: A2BK79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

415426:HBUT RS06925
gene id: 415426:HBUT_RS06925
uniprot id: A2BME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

415426:HBUT RS05735
gene id: 415426:HBUT_RS05735
uniprot id: A2BLT2
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS00885
gene id: 415426:HBUT_RS00885
uniprot id: A2BJ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

415426:HBUT RS00505
gene id: 415426:HBUT_RS00505
uniprot id: A2BJ11
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS08725
gene id: 415426:HBUT_RS08725
uniprot id: A2BNC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

415426:HBUT RS00010
gene id: 415426:HBUT_RS00010
uniprot id: A2BIS6
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS02000
gene id: 415426:HBUT_RS02000
uniprot id: A2BJU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high-temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to 1,3-diaminopropane to yield sym-norspermidine (bis(3-aminopropyl)amine). It can also synthesize thermospermine from spermidine with a very low activity.

415426:HBUT RS02695
gene id: 415426:HBUT_RS02695
uniprot id: A2BK69
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

415426:HBUT RS00365
gene id: 415426:HBUT_RS00365
uniprot id: A2BIY8
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

415426:HBUT RS08645
gene id: 415426:HBUT_RS08645
uniprot id: A2BNA6
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

415426:HBUT RS06165
gene id: 415426:HBUT_RS06165
uniprot id: A2BM05
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.
messages: Specifically catalyzes the decarboxylation of L-arginine to agmatine. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity.

415426:HBUT RS00475
gene id: 415426:HBUT_RS00475
uniprot id: A2BJ05
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

415426:HBUT RS00630
gene id: 415426:HBUT_RS00630
uniprot id: A2BJ36
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

415426:HBUT RS04105
gene id: 415426:HBUT_RS04105
uniprot id: A2BKX4
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

415426:HBUT RS04710
gene id: 415426:HBUT_RS04710
uniprot id: A2BL84
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

415426:HBUT RS07505
gene id: 415426:HBUT_RS07505
uniprot id: A2BMP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

415426:HBUT RS00220
gene id: 415426:HBUT_RS00220
uniprot id: A2BIW0
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

415426:HBUT RS00435
gene id: 415426:HBUT_RS00435
uniprot id: A2BIZ8
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

415426:HBUT RS00670
gene id: 415426:HBUT_RS00670
uniprot id: A2BJ45
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

415426:HBUT RS00090
gene id: 415426:HBUT_RS00090
uniprot id: A2BIT9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

415426:HBUT RS02095
gene id: 415426:HBUT_RS02095
uniprot id: A2BJV8
names: Similarity
messages: Belongs to the RuvB family.

415426:HBUT RS04865
gene id: 415426:HBUT_RS04865
uniprot id: A2BLB4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

415426:HBUT RS05140
gene id: 415426:HBUT_RS05140
uniprot id: A2BLG9
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

415426:HBUT RS08400
gene id: 415426:HBUT_RS08400
uniprot id: A2BN64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

415426:HBUT RS04600
gene id: 415426:HBUT_RS04600
uniprot id: A2BL64
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

415426:HBUT RS02330
gene id: 415426:HBUT_RS02330
uniprot id: A2BK03
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

415426:HBUT RS03160
gene id: 415426:HBUT_RS03160
uniprot id: A2BKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

415426:HBUT RS00260
gene id: 415426:HBUT_RS00260
uniprot id: A2BIW8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

415426:HBUT RS02870
gene id: 415426:HBUT_RS02870
uniprot id: A2BKA2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

415426:HBUT RS04355
gene id: 415426:HBUT_RS04355
uniprot id: A2BL20
names: Similarity
messages: Belongs to the GcvT family.

415426:HBUT RS04160
gene id: 415426:HBUT_RS04160
uniprot id: A2BKY5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

415426:HBUT RS08870
gene id: 415426:HBUT_RS08870
uniprot id: A2BKM9
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

415426:HBUT RS02305
gene id: 415426:HBUT_RS02305
uniprot id: A2BJZ8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

415426:HBUT RS08170
gene id: 415426:HBUT_RS08170
uniprot id: A2BN20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

415426:HBUT RS06620
gene id: 415426:HBUT_RS06620
uniprot id: A2BM88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

415426:HBUT RS08240
gene id: 415426:HBUT_RS08240
uniprot id: A2BN34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

415426:HBUT RS08370
gene id: 415426:HBUT_RS08370
uniprot id: A2BN58
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

415426:HBUT RS05930
gene id: 415426:HBUT_RS05930
uniprot id: A2BLW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

415426:HBUT RS01645
gene id: 415426:HBUT_RS01645
uniprot id: A2BJM3
names: Similarity
messages: Belongs to the LDH2/MDH2 oxidoreductase family.

415426:HBUT RS03580
gene id: 415426:HBUT_RS03580
uniprot id: A2BKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

415426:HBUT RS02715
gene id: 415426:HBUT_RS02715
uniprot id: A2BK73
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

415426:HBUT RS07285
gene id: 415426:HBUT_RS07285
uniprot id: A2BMK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

415426:HBUT RS02620
gene id: 415426:HBUT_RS02620
uniprot id: A2BK54
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

415426:HBUT RS02780
gene id: 415426:HBUT_RS02780
uniprot id: A2BK84
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

415426:HBUT RS06145
gene id: 415426:HBUT_RS06145
uniprot id: A2BM01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

415426:HBUT RS02505
gene id: 415426:HBUT_RS02505
uniprot id: A2BK32
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

415426:HBUT RS04995
gene id: 415426:HBUT_RS04995
uniprot id: A2BLE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

415426:HBUT RS07795
gene id: 415426:HBUT_RS07795
uniprot id: A2BMV0
names: Subcellular Location Annotation
messages: Cell membrane

415426:HBUT RS03215
gene id: 415426:HBUT_RS03215
uniprot id: A2BKG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

415426:HBUT RS08655
gene id: 415426:HBUT_RS08655
uniprot id: A2BNA8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

415426:HBUT RS08665
gene id: 415426:HBUT_RS08665
uniprot id: A2BNB0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

415426:HBUT RS05435
gene id: 415426:HBUT_RS05435
uniprot id: A2BLM3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

415426:HBUT RS04345
gene id: 415426:HBUT_RS04345
uniprot id: A2BL19
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

415426:HBUT RS06240
gene id: 415426:HBUT_RS06240
uniprot id: A2BM20
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

415426:HBUT RS05925
gene id: 415426:HBUT_RS05925
uniprot id: A2BLW2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

415426:HBUT RS02565
gene id: 415426:HBUT_RS02565
uniprot id: A2BK43
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

415426:HBUT RS02265
gene id: 415426:HBUT_RS02265
uniprot id: A2BJZ0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Part of the 30S ribosomal subunit.

415426:HBUT RS04460
gene id: 415426:HBUT_RS04460
uniprot id: A2BL40
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS04620
gene id: 415426:HBUT_RS04620
uniprot id: A2BL68
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.
messages: Belongs to the Cren7 family.
messages: Cytoplasm
messages: Methylated at multiple sites, to varying extents.
messages: Monomer.

415426:HBUT RS06900
gene id: 415426:HBUT_RS06900
uniprot id: A2BMD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

415426:HBUT RS04960
gene id: 415426:HBUT_RS04960
uniprot id: A2BLD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

415426:HBUT RS02395
gene id: 415426:HBUT_RS02395
uniprot id: A2BK15
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

415426:HBUT RS00980
gene id: 415426:HBUT_RS00980
uniprot id: A2BJA2
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS04390
gene id: 415426:HBUT_RS04390
uniprot id: A2BL26
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

415426:HBUT RS00815
gene id: 415426:HBUT_RS00815
uniprot id: A2BJ69
names: Similarity
messages: Belongs to the class-I fumarase family.

415426:HBUT RS02800
gene id: 415426:HBUT_RS02800
uniprot id: A2BK88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

415426:HBUT RS00795
gene id: 415426:HBUT_RS00795
uniprot id: A2BJ65
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

415426:HBUT RS06715
gene id: 415426:HBUT_RS06715
uniprot id: A2BMA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

415426:HBUT RS08260
gene id: 415426:HBUT_RS08260
uniprot id: A2BN38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

415426:HBUT RS07845
gene id: 415426:HBUT_RS07845
uniprot id: A2BMV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

415426:HBUT RS08585
gene id: 415426:HBUT_RS08585
uniprot id: A2BN95
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

415426:HBUT RS07665
gene id: 415426:HBUT_RS07665
uniprot id: A2BMS9
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS05320
gene id: 415426:HBUT_RS05320
uniprot id: A2BLK3
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS07905
gene id: 415426:HBUT_RS07905
uniprot id: A2BMX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

415426:HBUT RS02575
gene id: 415426:HBUT_RS02575
uniprot id: A2BK45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

415426:HBUT RS06890
gene id: 415426:HBUT_RS06890
uniprot id: A2BMD6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

415426:HBUT RS08330
gene id: 415426:HBUT_RS08330
uniprot id: A2BN50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

415426:HBUT RS03960
gene id: 415426:HBUT_RS03960
uniprot id: A2BKU6
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

415426:HBUT RS07980
gene id: 415426:HBUT_RS07980
uniprot id: A2BMY5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

415426:HBUT RS07805
gene id: 415426:HBUT_RS07805
uniprot id: A2BMV1
names: Similarity
messages: Belongs to the UPF0215 family.

415426:HBUT RS04700
gene id: 415426:HBUT_RS04700
uniprot id: A2BL82
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

415426:HBUT RS00330
gene id: 415426:HBUT_RS00330
uniprot id: A2BIY1
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS08435
gene id: 415426:HBUT_RS08435
uniprot id: A2BN71
names: Similarity
messages: Belongs to the peptidase C15 family.

415426:HBUT RS02775
gene id: 415426:HBUT_RS02775
uniprot id: A2BK83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

415426:HBUT RS07490
gene id: 415426:HBUT_RS07490
uniprot id: A2BMP6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

415426:HBUT RS03345
gene id: 415426:HBUT_RS03345
uniprot id: A2BKJ0
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

415426:HBUT RS05055
gene id: 415426:HBUT_RS05055
uniprot id: A2BLF2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

415426:HBUT RS04675
gene id: 415426:HBUT_RS04675
uniprot id: A2BL77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

415426:HBUT RS05275
gene id: 415426:HBUT_RS05275
uniprot id: A2BLJ5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

415426:HBUT RS00270
gene id: 415426:HBUT_RS00270
uniprot id: A2BIX0
names: Similarity
messages: Belongs to the SUI1 family.

415426:HBUT RS04815
gene id: 415426:HBUT_RS04815
uniprot id: A2BLA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

415426:HBUT RS08375
gene id: 415426:HBUT_RS08375
uniprot id: A2BN59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

415426:HBUT RS06775
gene id: 415426:HBUT_RS06775
uniprot id: A2BMB3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

415426:HBUT RS00230
gene id: 415426:HBUT_RS00230
uniprot id: A2BIW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homotetramer; although the tetramer contains four active sites, only two participate in the cleavage. Therefore, it should be considered as a dimer of dimers.

415426:HBUT RS07510
gene id: 415426:HBUT_RS07510
uniprot id: A2BMQ0
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS03820
gene id: 415426:HBUT_RS03820
uniprot id: A2BKS3
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

415426:HBUT RS08165
gene id: 415426:HBUT_RS08165
uniprot id: A2BN19
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

415426:HBUT RS02250
gene id: 415426:HBUT_RS02250
uniprot id: A2BJY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

415426:HBUT RS03110
gene id: 415426:HBUT_RS03110
uniprot id: A2BKE7
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS08230
gene id: 415426:HBUT_RS08230
uniprot id: A2BN32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

415426:HBUT RS06915
gene id: 415426:HBUT_RS06915
uniprot id: A2BME1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

415426:HBUT RS01630
gene id: 415426:HBUT_RS01630
uniprot id: A2BJM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

415426:HBUT RS07470
gene id: 415426:HBUT_RS07470
uniprot id: A2BMP3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

415426:HBUT RS04810
gene id: 415426:HBUT_RS04810
uniprot id: A2BLA3
names: Similarity
messages: Belongs to the type IA topoisomerase family.

415426:HBUT RS10000
gene id: 415426:HBUT_RS10000
uniprot id: A2BKT1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

415426:HBUT RS09105
gene id: 415426:HBUT_RS09105
uniprot id: A2BN17
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

415426:HBUT RS02970
gene id: 415426:HBUT_RS02970
uniprot id: A2BKC2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

415426:HBUT RS00820
gene id: 415426:HBUT_RS00820
uniprot id: A2BJ70
names: Similarity
messages: Belongs to the class-I fumarase family.

415426:HBUT RS08130
gene id: 415426:HBUT_RS08130
uniprot id: A2BN13
names: Similarity
messages: Belongs to the AOR/FOR family.

415426:HBUT RS04745
gene id: 415426:HBUT_RS04745
uniprot id: A2BL91
names: Similarity
messages: Belongs to the MCM family.

415426:HBUT RS00575
gene id: 415426:HBUT_RS00575
uniprot id: A2BJ25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

415426:HBUT RS08350
gene id: 415426:HBUT_RS08350
uniprot id: A2BN54
names: Similarity
messages: Belongs to the PDCD5 family.

415426:HBUT RS02675
gene id: 415426:HBUT_RS02675
uniprot id: A2BK65
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS05610
gene id: 415426:HBUT_RS05610
uniprot id: A2BLQ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

415426:HBUT RS07485
gene id: 415426:HBUT_RS07485
uniprot id: A2BMP5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

415426:HBUT RS07145
gene id: 415426:HBUT_RS07145
uniprot id: A2BMI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).

415426:HBUT RS04490
gene id: 415426:HBUT_RS04490
uniprot id: A2BL44
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

415426:HBUT RS07580
gene id: 415426:HBUT_RS07580
uniprot id: A2BMR3
names: Similarity
messages: Belongs to the UbiD family.

415426:HBUT RS02635
gene id: 415426:HBUT_RS02635
uniprot id: A2BK57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).

415426:HBUT RS02750
gene id: 415426:HBUT_RS02750
uniprot id: A2BK78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

415426:HBUT RS07855
gene id: 415426:HBUT_RS07855
uniprot id: A2BMW0
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

415426:HBUT RS01095
gene id: 415426:HBUT_RS01095
uniprot id: A2BJC2
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS08365
gene id: 415426:HBUT_RS08365
uniprot id: A2BN57
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

415426:HBUT RS04030
gene id: 415426:HBUT_RS04030
uniprot id: A2BKV9
names: Similarity
messages: Belongs to the UPF0252 family.

415426:HBUT RS00655
gene id: 415426:HBUT_RS00655
uniprot id: A2BJ42
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

415426:HBUT RS04990
gene id: 415426:HBUT_RS04990
uniprot id: A2BLE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

415426:HBUT RS05745
gene id: 415426:HBUT_RS05745
uniprot id: A2BLT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

415426:HBUT RS00560
gene id: 415426:HBUT_RS00560
uniprot id: A2BJ22
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

415426:HBUT RS02950
gene id: 415426:HBUT_RS02950
uniprot id: A2BKB8
names: Similarity
messages: Belongs to the SDO1/SBDS family.

415426:HBUT RS00550
gene id: 415426:HBUT_RS00550
uniprot id: A2BJ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

415426:HBUT RS02935
gene id: 415426:HBUT_RS02935
uniprot id: A2BKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

415426:HBUT RS08690
gene id: 415426:HBUT_RS08690
uniprot id: A2BNB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

415426:HBUT RS02955
gene id: 415426:HBUT_RS02955
uniprot id: A2BKB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

415426:HBUT RS04680
gene id: 415426:HBUT_RS04680
uniprot id: A2BL78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Binds two Mg(2+) per subunit.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.

415426:HBUT RS05545
gene id: 415426:HBUT_RS05545
uniprot id: A2BLP3
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

415426:HBUT RS02745
gene id: 415426:HBUT_RS02745
uniprot id: A2BK77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

415426:HBUT RS01050
gene id: 415426:HBUT_RS01050
uniprot id: A2BJB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

415426:HBUT RS02630
gene id: 415426:HBUT_RS02630
uniprot id: A2BK56
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

415426:HBUT RS00155
gene id: 415426:HBUT_RS00155
uniprot id: A2BIV2
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

415426:HBUT RS01070
gene id: 415426:HBUT_RS01070
uniprot id: A2BJB7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

415426:HBUT RS01660
gene id: 415426:HBUT_RS01660
uniprot id: A2BJM6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

415426:HBUT RS06545
gene id: 415426:HBUT_RS06545
uniprot id: A2BM73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

415426:HBUT RS06050
gene id: 415426:HBUT_RS06050
uniprot id: A2BLY6
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

415426:HBUT RS01260
gene id: 415426:HBUT_RS01260
uniprot id: A2BJF0
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

415426:HBUT RS01125
gene id: 415426:HBUT_RS01125
uniprot id: A2BJC8
names: Similarity
messages: Belongs to the RutC family.

415426:HBUT RS06850
gene id: 415426:HBUT_RS06850
uniprot id: A2BMC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

415426:HBUT RS04240
gene id: 415426:HBUT_RS04240
uniprot id: A2BL01
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS01685
gene id: 415426:HBUT_RS01685
uniprot id: A2BJN0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

415426:HBUT RS01120
gene id: 415426:HBUT_RS01120
uniprot id: A2BJC7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

415426:HBUT RS04790
gene id: 415426:HBUT_RS04790
uniprot id: A2BL99
names: Function
messages: Part of a potassium transport system.

415426:HBUT RS00175
gene id: 415426:HBUT_RS00175
uniprot id: A2BIS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

415426:HBUT RS06040
gene id: 415426:HBUT_RS06040
uniprot id: A2BLY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

415426:HBUT RS05845
gene id: 415426:HBUT_RS05845
uniprot id: A2BLV0
names: Similarity
messages: Belongs to the BtpA family.

415426:HBUT RS02215
gene id: 415426:HBUT_RS02215
uniprot id: A2BJY0
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS04560
gene id: 415426:HBUT_RS04560
uniprot id: A2BL57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

415426:HBUT RS07095
gene id: 415426:HBUT_RS07095
uniprot id: A2BMH3
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

415426:HBUT RS05620
gene id: 415426:HBUT_RS05620
uniprot id: A2BLQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

415426:HBUT RS07400
gene id: 415426:HBUT_RS07400
uniprot id: A2BMM9
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS05115
gene id: 415426:HBUT_RS05115
uniprot id: A2BLG5
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS03390
gene id: 415426:HBUT_RS03390
uniprot id: A2BKJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

415426:HBUT RS01870
gene id: 415426:HBUT_RS01870
uniprot id: A2BJR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

415426:HBUT RS08580
gene id: 415426:HBUT_RS08580
uniprot id: A2BN94
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

415426:HBUT RS05755
gene id: 415426:HBUT_RS05755
uniprot id: A2BLT6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

415426:HBUT RS06690
gene id: 415426:HBUT_RS06690
uniprot id: A2BM98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

415426:HBUT RS05840
gene id: 415426:HBUT_RS05840
uniprot id: A2BLU9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

415426:HBUT RS02295
gene id: 415426:HBUT_RS02295
uniprot id: A2BJZ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

415426:HBUT RS02765
gene id: 415426:HBUT_RS02765
uniprot id: A2BK81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

415426:HBUT RS04785
gene id: 415426:HBUT_RS04785
uniprot id: A2BL98
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

415426:HBUT RS06840
gene id: 415426:HBUT_RS06840
uniprot id: A2BMC6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

415426:HBUT RS08250
gene id: 415426:HBUT_RS08250
uniprot id: A2BN36
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

415426:HBUT RS08175
gene id: 415426:HBUT_RS08175
uniprot id: A2BN21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

415426:HBUT RS05030
gene id: 415426:HBUT_RS05030
uniprot id: A2BLE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

415426:HBUT RS08280
gene id: 415426:HBUT_RS08280
uniprot id: A2BN42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

415426:HBUT RS02960
gene id: 415426:HBUT_RS02960
uniprot id: A2BKC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteromeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

415426:HBUT RS08270
gene id: 415426:HBUT_RS08270
uniprot id: A2BN40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

415426:HBUT RS00570
gene id: 415426:HBUT_RS00570
uniprot id: A2BJ24
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

415426:HBUT RS08050
gene id: 415426:HBUT_RS08050
uniprot id: A2BMZ8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

415426:HBUT RS00205
gene id: 415426:HBUT_RS00205
uniprot id: A2BIV7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

415426:HBUT RS04670
gene id: 415426:HBUT_RS04670
uniprot id: A2BL76
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

415426:HBUT RS05670
gene id: 415426:HBUT_RS05670
uniprot id: A2BLR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

415426:HBUT RS03305
gene id: 415426:HBUT_RS03305
uniprot id: A2BKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

415426:HBUT RS03300
gene id: 415426:HBUT_RS03300
uniprot id: A2BKI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

415426:HBUT RS05065
gene id: 415426:HBUT_RS05065
uniprot id: A2BLF4
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

415426:HBUT RS05205
gene id: 415426:HBUT_RS05205
uniprot id: A2BLI2
names: Similarity
messages: Belongs to the peptidase C56 family.

415426:HBUT RS03275
gene id: 415426:HBUT_RS03275
uniprot id: A2BKH6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

415426:HBUT RS05415
gene id: 415426:HBUT_RS05415
uniprot id: A2BLM0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

415426:HBUT RS06700
gene id: 415426:HBUT_RS06700
uniprot id: A2BMA0
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

415426:HBUT RS05935
gene id: 415426:HBUT_RS05935
uniprot id: A2BLW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

415426:HBUT RS06855
gene id: 415426:HBUT_RS06855
uniprot id: A2BMC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

415426:HBUT RS01190
gene id: 415426:HBUT_RS01190
uniprot id: A2BJD9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

415426:HBUT RS02180
gene id: 415426:HBUT_RS02180
uniprot id: A2BJX3
names: Similarity
messages: Belongs to the UPF0273 family.

415426:HBUT RS04930
gene id: 415426:HBUT_RS04930
uniprot id: A2BLC7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

415426:HBUT RS04100
gene id: 415426:HBUT_RS04100
uniprot id: A2BKX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

415426:HBUT RS08255
gene id: 415426:HBUT_RS08255
uniprot id: A2BN37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

415426:HBUT RS01265
gene id: 415426:HBUT_RS01265
uniprot id: A2BJF1
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS03720
gene id: 415426:HBUT_RS03720
uniprot id: A2BKQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

415426:HBUT RS02585
gene id: 415426:HBUT_RS02585
uniprot id: A2BK47
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

415426:HBUT RS02235
gene id: 415426:HBUT_RS02235
uniprot id: A2BJY4
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

415426:HBUT RS07995
gene id: 415426:HBUT_RS07995
uniprot id: A2BMY8
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

415426:HBUT RS02300
gene id: 415426:HBUT_RS02300
uniprot id: A2BJZ7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

415426:HBUT RS03315
gene id: 415426:HBUT_RS03315
uniprot id: A2BKI4
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS08675
gene id: 415426:HBUT_RS08675
uniprot id: A2BNB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

415426:HBUT RS01170
gene id: 415426:HBUT_RS01170
uniprot id: A2BJD5
names: Similarity
messages: Belongs to the group II decarboxylase family.

415426:HBUT RS07155
gene id: 415426:HBUT_RS07155
uniprot id: A2BMI2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

415426:HBUT RS07180
gene id: 415426:HBUT_RS07180
uniprot id: A2BMI7
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

415426:HBUT RS04120
gene id: 415426:HBUT_RS04120
uniprot id: A2BKX7
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

415426:HBUT RS08245
gene id: 415426:HBUT_RS08245
uniprot id: A2BN35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

415426:HBUT RS08610
gene id: 415426:HBUT_RS08610
uniprot id: A2BN99
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

415426:HBUT RS05715
gene id: 415426:HBUT_RS05715
uniprot id: A2BLS8
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS00835
gene id: 415426:HBUT_RS00835
uniprot id: A2BJ73
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS08995
gene id: 415426:HBUT_RS08995
uniprot id: A2BM15
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

415426:HBUT RS05885
gene id: 415426:HBUT_RS05885
uniprot id: A2BLV6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.
messages: Belongs to the Cren7 family.
messages: Cytoplasm
messages: Methylated at multiple sites, to varying extents.
messages: Monomer.

415426:HBUT RS04775
gene id: 415426:HBUT_RS04775
uniprot id: A2BL96
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

415426:HBUT RS06360
gene id: 415426:HBUT_RS06360
uniprot id: A2BM41
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

415426:HBUT RS06995
gene id: 415426:HBUT_RS06995
uniprot id: A2BMF6
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS06860
gene id: 415426:HBUT_RS06860
uniprot id: A2BMD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

415426:HBUT RS04125
gene id: 415426:HBUT_RS04125
uniprot id: A2BKX8
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

415426:HBUT RS07685
gene id: 415426:HBUT_RS07685
uniprot id: A2BMT2
names: Similarity
messages: Belongs to the peptidase M20A family.

415426:HBUT RS06845
gene id: 415426:HBUT_RS06845
uniprot id: A2BMC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

415426:HBUT RS00590
gene id: 415426:HBUT_RS00590
uniprot id: A2BJ28
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

415426:HBUT RS00975
gene id: 415426:HBUT_RS00975
uniprot id: A2BJA1
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS01990
gene id: 415426:HBUT_RS01990
uniprot id: A2BJU0
names: Function
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.

415426:HBUT RS06835
gene id: 415426:HBUT_RS06835
uniprot id: A2BMC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

415426:HBUT RS03815
gene id: 415426:HBUT_RS03815
uniprot id: A2BKS2
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

415426:HBUT RS06290
gene id: 415426:HBUT_RS06290
uniprot id: A2BM28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

415426:HBUT RS04660
gene id: 415426:HBUT_RS04660
uniprot id: A2BL74
names: Similarity
messages: Belongs to the UPF0173 family.

415426:HBUT RS07655
gene id: 415426:HBUT_RS07655
uniprot id: A2BMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

415426:HBUT RS03765
gene id: 415426:HBUT_RS03765
uniprot id: A2BKR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

415426:HBUT RS05640
gene id: 415426:HBUT_RS05640
uniprot id: A2BLR3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

415426:HBUT RS03800
gene id: 415426:HBUT_RS03800
uniprot id: A2BKR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal MetE family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.

415426:HBUT RS08015
gene id: 415426:HBUT_RS08015
uniprot id: A2BMZ2
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

415426:HBUT RS08385
gene id: 415426:HBUT_RS08385
uniprot id: A2BN61
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS06095
gene id: 415426:HBUT_RS06095
uniprot id: A2BLZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

415426:HBUT RS05825
gene id: 415426:HBUT_RS05825
uniprot id: A2BLU7
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

415426:HBUT RS00335
gene id: 415426:HBUT_RS00335
uniprot id: A2BIY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

415426:HBUT RS02360
gene id: 415426:HBUT_RS02360
uniprot id: A2BK09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

415426:HBUT RS04370
gene id: 415426:HBUT_RS04370
uniprot id: A2BL23
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

415426:HBUT RS00860
gene id: 415426:HBUT_RS00860
uniprot id: A2BJ78
names: Similarity
messages: Belongs to the glutaredoxin family.

415426:HBUT RS06480
gene id: 415426:HBUT_RS06480
uniprot id: A2BM61
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

415426:HBUT RS04130
gene id: 415426:HBUT_RS04130
uniprot id: A2BKX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

415426:HBUT RS00095
gene id: 415426:HBUT_RS00095
uniprot id: A2BIU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

415426:HBUT RS07560
gene id: 415426:HBUT_RS07560
uniprot id: A2BMR0
names: Similarity
messages: Belongs to the PGI/PMI family.

415426:HBUT RS06920
gene id: 415426:HBUT_RS06920
uniprot id: A2BME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

415426:HBUT RS05740
gene id: 415426:HBUT_RS05740
uniprot id: A2BLT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

415426:HBUT RS04615
gene id: 415426:HBUT_RS04615
uniprot id: A2BL67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

415426:HBUT RS06825
gene id: 415426:HBUT_RS06825
uniprot id: A2BMC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

415426:HBUT RS01180
gene id: 415426:HBUT_RS01180
uniprot id: A2BJD7
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS02355
gene id: 415426:HBUT_RS02355
uniprot id: A2BK08
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

415426:HBUT RS02500
gene id: 415426:HBUT_RS02500
uniprot id: A2BK31
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

415426:HBUT RS06220
gene id: 415426:HBUT_RS06220
uniprot id: A2BM16
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

415426:HBUT RS08685
gene id: 415426:HBUT_RS08685
uniprot id: A2BNB4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

415426:HBUT RS03480
gene id: 415426:HBUT_RS03480
uniprot id: A2BKL5
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

415426:HBUT RS04715
gene id: 415426:HBUT_RS04715
uniprot id: A2BL85
names: Similarity
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.

415426:HBUT RS04025
gene id: 415426:HBUT_RS04025
uniprot id: A2BKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

415426:HBUT RS01405
gene id: 415426:HBUT_RS01405
uniprot id: A2BJH7
names: Similarity
messages: Belongs to the Nth/MutY family.

415426:HBUT RS06275
gene id: 415426:HBUT_RS06275
uniprot id: A2BM26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

415426:HBUT RS04410
gene id: 415426:HBUT_RS04410
uniprot id: A2BL30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

415426:HBUT RS05230
gene id: 415426:HBUT_RS05230
uniprot id: A2BLI7
names: Similarity
messages: Belongs to the AOR/FOR family.

415426:HBUT RS08620
gene id: 415426:HBUT_RS08620
uniprot id: A2BNA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

415426:HBUT RS02805
gene id: 415426:HBUT_RS02805
uniprot id: A2BK89
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

415426:HBUT RS02835
gene id: 415426:HBUT_RS02835
uniprot id: A2BK95
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

415426:HBUT RS00055
gene id: 415426:HBUT_RS00055
uniprot id: A2BIT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

415426:HBUT RS02985
gene id: 415426:HBUT_RS02985
uniprot id: A2BKC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

415426:HBUT RS02965
gene id: 415426:HBUT_RS02965
uniprot id: A2BKC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

415426:HBUT RS00645
gene id: 415426:HBUT_RS00645
uniprot id: A2BJ40
names: Similarity
messages: Belongs to the peptidase M20A family.

415426:HBUT RS05785
gene id: 415426:HBUT_RS05785
uniprot id: A2BLU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

415426:HBUT RS02535
gene id: 415426:HBUT_RS02535
uniprot id: A2BK38
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

415426:HBUT RS08275
gene id: 415426:HBUT_RS08275
uniprot id: A2BN41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

415426:HBUT RS00500
gene id: 415426:HBUT_RS00500
uniprot id: A2BJ10
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS07425
gene id: 415426:HBUT_RS07425
uniprot id: A2BMN4
names: Similarity
messages: Belongs to the MEMO1 family.

415426:HBUT RS04895
gene id: 415426:HBUT_RS04895
uniprot id: A2BLC0
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
messages: Binds 1 potassium ion per subunit.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

415426:HBUT RS03380
gene id: 415426:HBUT_RS03380
uniprot id: A2BKJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

415426:HBUT RS08105
gene id: 415426:HBUT_RS08105
uniprot id: A2BN08
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

415426:HBUT RS03905
gene id: 415426:HBUT_RS03905
uniprot id: A2BKT7
names: Similarity
messages: Belongs to the archaeal ATPase family.

415426:HBUT RS05560
gene id: 415426:HBUT_RS05560
uniprot id: A2BLP5
names: Similarity
messages: Belongs to the UPF0045 family.

415426:HBUT RS00855
gene id: 415426:HBUT_RS00855
uniprot id: A2BJ77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

415426:HBUT RS03180
gene id: 415426:HBUT_RS03180
uniprot id: A2BKG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

415426:HBUT RS01940
gene id: 415426:HBUT_RS01940
uniprot id: A2BJT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

415426:HBUT RS04265
gene id: 415426:HBUT_RS04265
uniprot id: A2BL06
names: Subcellular Location Annotation
messages: Membrane

415426:HBUT RS02680
gene id: 415426:HBUT_RS02680
uniprot id: A2BK66
names: Similarity
messages: Belongs to the peptidase S9C family.

415426:HBUT RS08600
gene id: 415426:HBUT_RS08600
uniprot id: A2BN98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

415426:HBUT RS07975
gene id: 415426:HBUT_RS07975
uniprot id: A2BMY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

415426:HBUT RS05395
gene id: 415426:HBUT_RS05395
uniprot id: A2BLL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

415426:HBUT RS01760
gene id: 415426:HBUT_RS01760
uniprot id: A2BJP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

415426:HBUT RS03155
gene id: 415426:HBUT_RS03155
uniprot id: A2BKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

415426:HBUT RS02195
gene id: 415426:HBUT_RS02195
uniprot id: A2BJX6
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Can use ATP, ADP and GTP, but not CTP, TTP or NAD(+).