411154:GFO RS00450
gene id: 411154:GFO_RS00450
uniprot id: A0LXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

411154:GFO RS07890
gene id: 411154:GFO_RS07890
uniprot id: A0M206
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

411154:GFO RS14370
gene id: 411154:GFO_RS14370
uniprot id: A0M5U7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

411154:GFO RS15415
gene id: 411154:GFO_RS15415
uniprot id: A0M6G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

411154:GFO RS13385
gene id: 411154:GFO_RS13385
uniprot id: A0M598
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

411154:GFO RS06970
gene id: 411154:GFO_RS06970
uniprot id: A0M1G5
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

411154:GFO RS11195
gene id: 411154:GFO_RS11195
uniprot id: A0M3Z3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

411154:GFO RS12865
gene id: 411154:GFO_RS12865
uniprot id: A0M4Z2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

411154:GFO RS00210
gene id: 411154:GFO_RS00210
uniprot id: A0LXD9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

411154:GFO RS16380
gene id: 411154:GFO_RS16380
uniprot id: A0M714
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS10215
gene id: 411154:GFO_RS10215
uniprot id: A0M3E2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

411154:GFO RS10055
gene id: 411154:GFO_RS10055
uniprot id: A0M3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS03595
gene id: 411154:GFO_RS03595
uniprot id: A0LZE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

411154:GFO RS13635
gene id: 411154:GFO_RS13635
uniprot id: A0M5E9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

411154:GFO RS01050
gene id: 411154:GFO_RS01050
uniprot id: A0LXW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

411154:GFO RS03815
gene id: 411154:GFO_RS03815
uniprot id: A0LZI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

411154:GFO RS13420
gene id: 411154:GFO_RS13420
uniprot id: A0M5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS01855
gene id: 411154:GFO_RS01855
uniprot id: A0LYC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

411154:GFO RS11885
gene id: 411154:GFO_RS11885
uniprot id: A0M4D4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

411154:GFO RS07710
gene id: 411154:GFO_RS07710
uniprot id: A0M1X0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

411154:GFO RS15535
gene id: 411154:GFO_RS15535
uniprot id: A0M6J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

411154:GFO RS05900
gene id: 411154:GFO_RS05900
uniprot id: A0M0U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

411154:GFO RS12920
gene id: 411154:GFO_RS12920
uniprot id: A0M502
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

411154:GFO RS12730
gene id: 411154:GFO_RS12730
uniprot id: A0M4W4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

411154:GFO RS15600
gene id: 411154:GFO_RS15600
uniprot id: A0M6K5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

411154:GFO RS12770
gene id: 411154:GFO_RS12770
uniprot id: A0M4X2
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

411154:GFO RS14940
gene id: 411154:GFO_RS14940
uniprot id: A0M672
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

411154:GFO RS16060
gene id: 411154:GFO_RS16060
uniprot id: A0M6U9
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

411154:GFO RS00465
gene id: 411154:GFO_RS00465
uniprot id: A0LXI8
names: Similarity
messages: Belongs to the sigma-54 factor family.

411154:GFO RS04610
gene id: 411154:GFO_RS04610
uniprot id: A0M014
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS16405
gene id: 411154:GFO_RS16405
uniprot id: A0M719
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

411154:GFO RS15805
gene id: 411154:GFO_RS15805
uniprot id: A0M6P6
names: Similarity
messages: Belongs to the peptidase S9A family.

411154:GFO RS00655
gene id: 411154:GFO_RS00655
uniprot id: A0LXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

411154:GFO RS14990
gene id: 411154:GFO_RS14990
uniprot id: A0M682
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

411154:GFO RS13685
gene id: 411154:GFO_RS13685
uniprot id: A0M5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

411154:GFO RS09850
gene id: 411154:GFO_RS09850
uniprot id: A0M365
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

411154:GFO RS15335
gene id: 411154:GFO_RS15335
uniprot id: A0M6F2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

411154:GFO RS11875
gene id: 411154:GFO_RS11875
uniprot id: A0M4D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

411154:GFO RS16565
gene id: 411154:GFO_RS16565
uniprot id: A0M755
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

411154:GFO RS00230
gene id: 411154:GFO_RS00230
uniprot id: A0LXE3
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

411154:GFO RS07135
gene id: 411154:GFO_RS07135
uniprot id: A0M1J9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

411154:GFO RS03400
gene id: 411154:GFO_RS03400
uniprot id: A0LZ97
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS00995
gene id: 411154:GFO_RS00995
uniprot id: A0LXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

411154:GFO RS09745
gene id: 411154:GFO_RS09745
uniprot id: A0M343
names: Similarity
messages: Belongs to the CvfB family.

411154:GFO RS00960
gene id: 411154:GFO_RS00960
uniprot id: A0LXU1
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13145
gene id: 411154:GFO_RS13145
uniprot id: A0M547
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS06610
gene id: 411154:GFO_RS06610
uniprot id: A0M195
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

411154:GFO RS03320
gene id: 411154:GFO_RS03320
uniprot id: A0LZ81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

411154:GFO RS00145
gene id: 411154:GFO_RS00145
uniprot id: A0LXC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

411154:GFO RS05225
gene id: 411154:GFO_RS05225
uniprot id: A0M0D9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

411154:GFO RS05080
gene id: 411154:GFO_RS05080
uniprot id: A0M0B0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

411154:GFO RS07640
gene id: 411154:GFO_RS07640
uniprot id: A0M1V5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

411154:GFO RS00765
gene id: 411154:GFO_RS00765
uniprot id: A0LXP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

411154:GFO RS15170
gene id: 411154:GFO_RS15170
uniprot id: A0M6B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

411154:GFO RS07705
gene id: 411154:GFO_RS07705
uniprot id: A0M1W9
names: Similarity
messages: Belongs to the RutC family.

411154:GFO RS09870
gene id: 411154:GFO_RS09870
uniprot id: A0M369
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

411154:GFO RS16810
gene id: 411154:GFO_RS16810
uniprot id: A0M7A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS00445
gene id: 411154:GFO_RS00445
uniprot id: A0LXI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

411154:GFO RS09120
gene id: 411154:GFO_RS09120
uniprot id: A0M2R1
names: Similarity
messages: Belongs to the peptidase U62 family.

411154:GFO RS13305
gene id: 411154:GFO_RS13305
uniprot id: A0M582
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

411154:GFO RS13280
gene id: 411154:GFO_RS13280
uniprot id: A0M577
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

411154:GFO RS15090
gene id: 411154:GFO_RS15090
uniprot id: A0M6A2
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS14430
gene id: 411154:GFO_RS14430
uniprot id: A0M5W4
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

411154:GFO RS09790
gene id: 411154:GFO_RS09790
uniprot id: A0M353
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

411154:GFO RS01085
gene id: 411154:GFO_RS01085
uniprot id: A0LXW7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS10985
gene id: 411154:GFO_RS10985
uniprot id: A0M3V1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

411154:GFO RS09175
gene id: 411154:GFO_RS09175
uniprot id: A0M2S3
names: Similarity
messages: Belongs to the WrbA family.

411154:GFO RS07450
gene id: 411154:GFO_RS07450
uniprot id: A0M039
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

411154:GFO RS15650
gene id: 411154:GFO_RS15650
uniprot id: A0M6L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

411154:GFO RS02960
gene id: 411154:GFO_RS02960
uniprot id: A0LZ05
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

411154:GFO RS08620
gene id: 411154:GFO_RS08620
uniprot id: A0M2G0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

411154:GFO RS01525
gene id: 411154:GFO_RS01525
uniprot id: A0LY57
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

411154:GFO RS14600
gene id: 411154:GFO_RS14600
uniprot id: A0M600
names: Similarity
messages: Belongs to the histone deacetylase family.

411154:GFO RS11785
gene id: 411154:GFO_RS11785
uniprot id: A0M4B2
names: Similarity
messages: Belongs to the sterol desaturase family.

411154:GFO RS13165
gene id: 411154:GFO_RS13165
uniprot id: A0M553
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS04525
gene id: 411154:GFO_RS04525
uniprot id: A0LZZ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

411154:GFO RS04905
gene id: 411154:GFO_RS04905
uniprot id: A0M074
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

411154:GFO RS15145
gene id: 411154:GFO_RS15145
uniprot id: A0M6B3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

411154:GFO RS11915
gene id: 411154:GFO_RS11915
uniprot id: A0M4E0
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS10750
gene id: 411154:GFO_RS10750
uniprot id: A0M3Q3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

411154:GFO RS10285
gene id: 411154:GFO_RS10285
uniprot id: A0M3F6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

411154:GFO RS16800
gene id: 411154:GFO_RS16800
uniprot id: A0M7A4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

411154:GFO RS00660
gene id: 411154:GFO_RS00660
uniprot id: A0LXM8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

411154:GFO RS13345
gene id: 411154:GFO_RS13345
uniprot id: A0M590
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

411154:GFO RS02980
gene id: 411154:GFO_RS02980
uniprot id: A0LZ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

411154:GFO RS16190
gene id: 411154:GFO_RS16190
uniprot id: A0M6X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

411154:GFO RS08960
gene id: 411154:GFO_RS08960
uniprot id: A0M2M8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

411154:GFO RS10505
gene id: 411154:GFO_RS10505
uniprot id: A0M3K1
names: Similarity
messages: Belongs to the group II decarboxylase family.

411154:GFO RS15320
gene id: 411154:GFO_RS15320
uniprot id: A0M6E9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

411154:GFO RS01680
gene id: 411154:GFO_RS01680
uniprot id: A0LY92
names: Similarity
messages: Belongs to the EPSP synthase family.

411154:GFO RS00040
gene id: 411154:GFO_RS00040
uniprot id: A0LXA5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

411154:GFO RS14735
gene id: 411154:GFO_RS14735
uniprot id: A0M630
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

411154:GFO RS02020
gene id: 411154:GFO_RS02020
uniprot id: A0LYG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS06840
gene id: 411154:GFO_RS06840
uniprot id: A0M1D9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

411154:GFO RS07365
gene id: 411154:GFO_RS07365
uniprot id: A0M1P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

411154:GFO RS09905
gene id: 411154:GFO_RS09905
uniprot id: A0M376
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

411154:GFO RS04710
gene id: 411154:GFO_RS04710
uniprot id: A0M035
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

411154:GFO RS10235
gene id: 411154:GFO_RS10235
uniprot id: A0M3E6
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS09935
gene id: 411154:GFO_RS09935
uniprot id: A0M382
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

411154:GFO RS16475
gene id: 411154:GFO_RS16475
uniprot id: A0M732
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

411154:GFO RS05455
gene id: 411154:GFO_RS05455
uniprot id: A0M0J2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

411154:GFO RS07060
gene id: 411154:GFO_RS07060
uniprot id: A0M1I4
names: Similarity
messages: Belongs to the peptidase C40 family.

411154:GFO RS01395
gene id: 411154:GFO_RS01395
uniprot id: A0LY29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS00470
gene id: 411154:GFO_RS00470
uniprot id: A0LXI9
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

411154:GFO RS03795
gene id: 411154:GFO_RS03795
uniprot id: A0LZI0
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS06200
gene id: 411154:GFO_RS06200
uniprot id: A0M108
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

411154:GFO RS07595
gene id: 411154:GFO_RS07595
uniprot id: A0M1U6
names: Similarity
messages: Belongs to the SUI1 family.

411154:GFO RS05485
gene id: 411154:GFO_RS05485
uniprot id: A0M0J9
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS00975
gene id: 411154:GFO_RS00975
uniprot id: A0LXU4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

411154:GFO RS13560
gene id: 411154:GFO_RS13560
uniprot id: A0M5D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

411154:GFO RS11910
gene id: 411154:GFO_RS11910
uniprot id: A0M4D9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

411154:GFO RS13720
gene id: 411154:GFO_RS13720
uniprot id: A0M5G5
names: Similarity
messages: Belongs to the glutamate synthase family.

411154:GFO RS14050
gene id: 411154:GFO_RS14050
uniprot id: A0M5M8
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS15865
gene id: 411154:GFO_RS15865
uniprot id: A0M6Q9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

411154:GFO RS03270
gene id: 411154:GFO_RS03270
uniprot id: A0LZ71
names: Similarity
messages: Belongs to the SusD family.

411154:GFO RS11880
gene id: 411154:GFO_RS11880
uniprot id: A0M4D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS15395
gene id: 411154:GFO_RS15395
uniprot id: A0M6G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

411154:GFO RS14420
gene id: 411154:GFO_RS14420
uniprot id: A0M5V9
names: Similarity
messages: Belongs to the UPF0045 family.

411154:GFO RS06170
gene id: 411154:GFO_RS06170
uniprot id: A0M102
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

411154:GFO RS08225
gene id: 411154:GFO_RS08225
uniprot id: A0M280
names: Similarity
messages: Belongs to the pirin family.

411154:GFO RS03145
gene id: 411154:GFO_RS03145
uniprot id: A0LZ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

411154:GFO RS08235
gene id: 411154:GFO_RS08235
uniprot id: A0M282
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

411154:GFO RS15400
gene id: 411154:GFO_RS15400
uniprot id: A0M6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

411154:GFO RS07155
gene id: 411154:GFO_RS07155
uniprot id: A0M1K3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

411154:GFO RS17035
gene id: 411154:GFO_RS17035
uniprot id: A0M7F3
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

411154:GFO RS03590
gene id: 411154:GFO_RS03590
uniprot id: A0LZD9
names: Similarity
messages: Belongs to the arginase family.

411154:GFO RS05350
gene id: 411154:GFO_RS05350
uniprot id: A0M0G8
names: Similarity
messages: Belongs to the pirin family.

411154:GFO RS01730
gene id: 411154:GFO_RS01730
uniprot id: A0LYA2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

411154:GFO RS03940
gene id: 411154:GFO_RS03940
uniprot id: A0LZK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

411154:GFO RS08490
gene id: 411154:GFO_RS08490
uniprot id: A0M2D4
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS10070
gene id: 411154:GFO_RS10070
uniprot id: A0M3B1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

411154:GFO RS14560
gene id: 411154:GFO_RS14560
uniprot id: A0M5Z2
names: Subcellular Location Annotation
messages: Cytoplasm

411154:GFO RS03165
gene id: 411154:GFO_RS03165
uniprot id: A0LZ47
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

411154:GFO RS03790
gene id: 411154:GFO_RS03790
uniprot id: A0LZH9
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS03310
gene id: 411154:GFO_RS03310
uniprot id: A0LZ79
names: Similarity
messages: Belongs to the ribulokinase family.

411154:GFO RS11930
gene id: 411154:GFO_RS11930
uniprot id: A0M4E3
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS03785
gene id: 411154:GFO_RS03785
uniprot id: A0LZH8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

411154:GFO RS00385
gene id: 411154:GFO_RS00385
uniprot id: A0LXH3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

411154:GFO RS08800
gene id: 411154:GFO_RS08800
uniprot id: A0M2K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

411154:GFO RS08460
gene id: 411154:GFO_RS08460
uniprot id: A0M2C8
names: Similarity
messages: Belongs to the ArsC family.

411154:GFO RS05715
gene id: 411154:GFO_RS05715
uniprot id: A0M0Q2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

411154:GFO RS10130
gene id: 411154:GFO_RS10130
uniprot id: A0M3C3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

411154:GFO RS02635
gene id: 411154:GFO_RS02635
uniprot id: A0LYU4
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

411154:GFO RS15280
gene id: 411154:GFO_RS15280
uniprot id: A0M6E0
names: Miscellaneous
names: Subcellular Location Annotation
messages: According to PubMed:17107561, motility has not been observed in Gramella forsetii although it possesses genes known to be required for gliding motility.
messages: Cell membrane

411154:GFO RS03395
gene id: 411154:GFO_RS03395
uniprot id: A0LZ96
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS11155
gene id: 411154:GFO_RS11155
uniprot id: A0M3Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

411154:GFO RS13055
gene id: 411154:GFO_RS13055
uniprot id: A0M529
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

411154:GFO RS11335
gene id: 411154:GFO_RS11335
uniprot id: A0M418
names: Similarity
messages: Belongs to the HSP15 family.

411154:GFO RS16130
gene id: 411154:GFO_RS16130
uniprot id: A0M6W4
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS08185
gene id: 411154:GFO_RS08185
uniprot id: A0M272
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

411154:GFO RS16665
gene id: 411154:GFO_RS16665
uniprot id: A0M777
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS00860
gene id: 411154:GFO_RS00860
uniprot id: A0LXS0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS10020
gene id: 411154:GFO_RS10020
uniprot id: A0M3A1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS14100
gene id: 411154:GFO_RS14100
uniprot id: A0M5P3
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS04505
gene id: 411154:GFO_RS04505
uniprot id: A0LZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

411154:GFO RS16350
gene id: 411154:GFO_RS16350
uniprot id: A0M708
names: Similarity
messages: Belongs to the SusD family.

411154:GFO RS08705
gene id: 411154:GFO_RS08705
uniprot id: A0M2I0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS03455
gene id: 411154:GFO_RS03455
uniprot id: A0LZA8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

411154:GFO RS06880
gene id: 411154:GFO_RS06880
uniprot id: A0M1E7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

411154:GFO RS16705
gene id: 411154:GFO_RS16705
uniprot id: A0M785
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS09675
gene id: 411154:GFO_RS09675
uniprot id: A0M329
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS10890
gene id: 411154:GFO_RS10890
uniprot id: A0M3T2
names: Similarity
messages: Belongs to the UPF0173 family.

411154:GFO RS15220
gene id: 411154:GFO_RS15220
uniprot id: A0M6C8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

411154:GFO RS03765
gene id: 411154:GFO_RS03765
uniprot id: A0LZH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

411154:GFO RS00885
gene id: 411154:GFO_RS00885
uniprot id: A0LXS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

411154:GFO RS01630
gene id: 411154:GFO_RS01630
uniprot id: A0LY82
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

411154:GFO RS15495
gene id: 411154:GFO_RS15495
uniprot id: A0M6I4
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

411154:GFO RS16840
gene id: 411154:GFO_RS16840
uniprot id: A0M7B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

411154:GFO RS01030
gene id: 411154:GFO_RS01030
uniprot id: A0LXV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

411154:GFO RS08935
gene id: 411154:GFO_RS08935
uniprot id: A0M2M3
names: Similarity
messages: Belongs to the type IB topoisomerase family.

411154:GFO RS05600
gene id: 411154:GFO_RS05600
uniprot id: A0M0M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

411154:GFO RS11150
gene id: 411154:GFO_RS11150
uniprot id: A0M3Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

411154:GFO RS02515
gene id: 411154:GFO_RS02515
uniprot id: A0LYR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

411154:GFO RS13150
gene id: 411154:GFO_RS13150
uniprot id: A0M549
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

411154:GFO RS06235
gene id: 411154:GFO_RS06235
uniprot id: A0M116
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

411154:GFO RS11960
gene id: 411154:GFO_RS11960
uniprot id: A0M4E9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

411154:GFO RS16135
gene id: 411154:GFO_RS16135
uniprot id: A0M6W5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

411154:GFO RS10790
gene id: 411154:GFO_RS10790
uniprot id: A0M3R2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

411154:GFO RS03695
gene id: 411154:GFO_RS03695
uniprot id: A0LZG0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

411154:GFO RS15685
gene id: 411154:GFO_RS15685
uniprot id: A0M6M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

411154:GFO RS16270
gene id: 411154:GFO_RS16270
uniprot id: A0M6Z3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

411154:GFO RS03365
gene id: 411154:GFO_RS03365
uniprot id: A0LZ90
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

411154:GFO RS01490
gene id: 411154:GFO_RS01490
uniprot id: A0LY48
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

411154:GFO RS15530
gene id: 411154:GFO_RS15530
uniprot id: A0M6J1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

411154:GFO RS12495
gene id: 411154:GFO_RS12495
uniprot id: A0M4R4
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

411154:GFO RS03095
gene id: 411154:GFO_RS03095
uniprot id: A0LZ33
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS04730
gene id: 411154:GFO_RS04730
uniprot id: A0M039
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

411154:GFO RS13690
gene id: 411154:GFO_RS13690
uniprot id: A0M5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

411154:GFO RS14900
gene id: 411154:GFO_RS14900
uniprot id: A0M664
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

411154:GFO RS13845
gene id: 411154:GFO_RS13845
uniprot id: A0M5I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

411154:GFO RS11295
gene id: 411154:GFO_RS11295
uniprot id: A0M410
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

411154:GFO RS01650
gene id: 411154:GFO_RS01650
uniprot id: A0LY86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

411154:GFO RS14930
gene id: 411154:GFO_RS14930
uniprot id: A0M670
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

411154:GFO RS14585
gene id: 411154:GFO_RS14585
uniprot id: A0M5Z7
names: Similarity
messages: Belongs to the UPF0102 family.

411154:GFO RS08660
gene id: 411154:GFO_RS08660
uniprot id: A0M2G8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

411154:GFO RS02230
gene id: 411154:GFO_RS02230
uniprot id: A0LYK9
names: Similarity
messages: Belongs to the glutamine synthetase family.

411154:GFO RS08035
gene id: 411154:GFO_RS08035
uniprot id: A0M237
names: Similarity
messages: Belongs to the SusD family.

411154:GFO RS06205
gene id: 411154:GFO_RS06205
uniprot id: A0M109
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

411154:GFO RS17255
gene id: 411154:GFO_RS17255
uniprot id: A0M240
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

411154:GFO RS03835
gene id: 411154:GFO_RS03835
uniprot id: A0LZI8
names: Similarity
messages: Belongs to the peptidase M16 family.

411154:GFO RS11190
gene id: 411154:GFO_RS11190
uniprot id: A0M3Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

411154:GFO RS15960
gene id: 411154:GFO_RS15960
uniprot id: A0M6S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

411154:GFO RS02160
gene id: 411154:GFO_RS02160
uniprot id: A0LYJ3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

411154:GFO RS04620
gene id: 411154:GFO_RS04620
uniprot id: A0M016
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

411154:GFO RS08010
gene id: 411154:GFO_RS08010
uniprot id: A0M232
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

411154:GFO RS12910
gene id: 411154:GFO_RS12910
uniprot id: A0M4Z9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

411154:GFO RS08555
gene id: 411154:GFO_RS08555
uniprot id: A0M2E7
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

411154:GFO RS04495
gene id: 411154:GFO_RS04495
uniprot id: A0LZY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

411154:GFO RS13400
gene id: 411154:GFO_RS13400
uniprot id: A0M5A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

411154:GFO RS11950
gene id: 411154:GFO_RS11950
uniprot id: A0M4E7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

411154:GFO RS12750
gene id: 411154:GFO_RS12750
uniprot id: A0M4W8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

411154:GFO RS09010
gene id: 411154:GFO_RS09010
uniprot id: A0M2N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

411154:GFO RS13315
gene id: 411154:GFO_RS13315
uniprot id: A0M584
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

411154:GFO RS01930
gene id: 411154:GFO_RS01930
uniprot id: A0LYE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

411154:GFO RS10625
gene id: 411154:GFO_RS10625
uniprot id: A0M3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

411154:GFO RS15550
gene id: 411154:GFO_RS15550
uniprot id: A0M6J5
names: Similarity
messages: Belongs to the Skp family.

411154:GFO RS07540
gene id: 411154:GFO_RS07540
uniprot id: A0M1T5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

411154:GFO RS06920
gene id: 411154:GFO_RS06920
uniprot id: A0M1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS14090
gene id: 411154:GFO_RS14090
uniprot id: A0M5P1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

411154:GFO RS05280
gene id: 411154:GFO_RS05280
uniprot id: A0M0F1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

411154:GFO RS02845
gene id: 411154:GFO_RS02845
uniprot id: A0LYY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

411154:GFO RS11205
gene id: 411154:GFO_RS11205
uniprot id: A0M3Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

411154:GFO RS16045
gene id: 411154:GFO_RS16045
uniprot id: A0M6U6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

411154:GFO RS13705
gene id: 411154:GFO_RS13705
uniprot id: A0M5G2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

411154:GFO RS13050
gene id: 411154:GFO_RS13050
uniprot id: A0M528
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS01605
gene id: 411154:GFO_RS01605
uniprot id: A0LY75
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

411154:GFO RS11350
gene id: 411154:GFO_RS11350
uniprot id: A0M421
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

411154:GFO RS11245
gene id: 411154:GFO_RS11245
uniprot id: A0M400
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

411154:GFO RS12195
gene id: 411154:GFO_RS12195
uniprot id: A0M4J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

411154:GFO RS03275
gene id: 411154:GFO_RS03275
uniprot id: A0LZ72
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

411154:GFO RS08265
gene id: 411154:GFO_RS08265
uniprot id: A0M288
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

411154:GFO RS05150
gene id: 411154:GFO_RS05150
uniprot id: A0M0C4
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

411154:GFO RS12700
gene id: 411154:GFO_RS12700
uniprot id: A0M4V8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

411154:GFO RS02930
gene id: 411154:GFO_RS02930
uniprot id: A0LYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

411154:GFO RS14125
gene id: 411154:GFO_RS14125
uniprot id: A0M5P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

411154:GFO RS07610
gene id: 411154:GFO_RS07610
uniprot id: A0M1U9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

411154:GFO RS08725
gene id: 411154:GFO_RS08725
uniprot id: A0M2I4
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS05300
gene id: 411154:GFO_RS05300
uniprot id: A0M0F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

411154:GFO RS08440
gene id: 411154:GFO_RS08440
uniprot id: A0M2C4
names: Similarity
messages: Belongs to the threonine aldolase family.

411154:GFO RS12855
gene id: 411154:GFO_RS12855
uniprot id: A0M4Z0
names: Similarity
messages: Belongs to the peptidase S51 family.

411154:GFO RS05100
gene id: 411154:GFO_RS05100
uniprot id: A0M0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS12940
gene id: 411154:GFO_RS12940
uniprot id: A0M506
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

411154:GFO RS04740
gene id: 411154:GFO_RS04740
uniprot id: A0M041
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS15405
gene id: 411154:GFO_RS15405
uniprot id: A0M6G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

411154:GFO RS05090
gene id: 411154:GFO_RS05090
uniprot id: A0M0B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

411154:GFO RS12590
gene id: 411154:GFO_RS12590
uniprot id: A0M4T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

411154:GFO RS06855
gene id: 411154:GFO_RS06855
uniprot id: A0M1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS13335
gene id: 411154:GFO_RS13335
uniprot id: A0M588
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

411154:GFO RS12610
gene id: 411154:GFO_RS12610
uniprot id: A0M4U0
names: Similarity
messages: Belongs to the UPF0246 family.

411154:GFO RS06615
gene id: 411154:GFO_RS06615
uniprot id: A0M196
names: Similarity
messages: Belongs to the universal stress protein A family.

411154:GFO RS13395
gene id: 411154:GFO_RS13395
uniprot id: A0M5A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

411154:GFO RS00870
gene id: 411154:GFO_RS00870
uniprot id: A0LXS2
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

411154:GFO RS00625
gene id: 411154:GFO_RS00625
uniprot id: A0LXM0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

411154:GFO RS00910
gene id: 411154:GFO_RS00910
uniprot id: A0LXT1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

411154:GFO RS07065
gene id: 411154:GFO_RS07065
uniprot id: A0M1I5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

411154:GFO RS02380
gene id: 411154:GFO_RS02380
uniprot id: A0LYP0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

411154:GFO RS01830
gene id: 411154:GFO_RS01830
uniprot id: A0LYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

411154:GFO RS06985
gene id: 411154:GFO_RS06985
uniprot id: A0M1G8
names: Similarity
messages: Belongs to the peptidase C56 family.

411154:GFO RS03485
gene id: 411154:GFO_RS03485
uniprot id: A0LZB6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

411154:GFO RS16450
gene id: 411154:GFO_RS16450
uniprot id: A0M728
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

411154:GFO RS14870
gene id: 411154:GFO_RS14870
uniprot id: A0M658
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

411154:GFO RS00495
gene id: 411154:GFO_RS00495
uniprot id: A0LXJ4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

411154:GFO RS10895
gene id: 411154:GFO_RS10895
uniprot id: A0M3T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

411154:GFO RS11140
gene id: 411154:GFO_RS11140
uniprot id: A0M3Y2
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

411154:GFO RS10290
gene id: 411154:GFO_RS10290
uniprot id: A0M3F7
names: Similarity
messages: Belongs to the nitroreductase family.

411154:GFO RS15520
gene id: 411154:GFO_RS15520
uniprot id: A0M6I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

411154:GFO RS05620
gene id: 411154:GFO_RS05620
uniprot id: A0M0N1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

411154:GFO RS05950
gene id: 411154:GFO_RS05950
uniprot id: A0M0V5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

411154:GFO RS06695
gene id: 411154:GFO_RS06695
uniprot id: A0M1B2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

411154:GFO RS14505
gene id: 411154:GFO_RS14505
uniprot id: A0M5Y1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

411154:GFO RS14465
gene id: 411154:GFO_RS14465
uniprot id: A0M5X1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

411154:GFO RS16960
gene id: 411154:GFO_RS16960
uniprot id: A0M7D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

411154:GFO RS16245
gene id: 411154:GFO_RS16245
uniprot id: A0M6Y8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

411154:GFO RS13695
gene id: 411154:GFO_RS13695
uniprot id: A0M5G0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

411154:GFO RS16695
gene id: 411154:GFO_RS16695
uniprot id: A0M783
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

411154:GFO RS01075
gene id: 411154:GFO_RS01075
uniprot id: A0LXW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

411154:GFO RS16775
gene id: 411154:GFO_RS16775
uniprot id: A0M799
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13800
gene id: 411154:GFO_RS13800
uniprot id: A0M5H7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

411154:GFO RS15710
gene id: 411154:GFO_RS15710
uniprot id: A0M6M7
names: Similarity
messages: Belongs to the peptidase C40 family.

411154:GFO RS04975
gene id: 411154:GFO_RS04975
uniprot id: A0M089
names: Similarity
messages: Belongs to the phosphohexose mutase family.

411154:GFO RS01220
gene id: 411154:GFO_RS01220
uniprot id: A0LXZ6
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS15995
gene id: 411154:GFO_RS15995
uniprot id: A0M6T6
names: Similarity
messages: Belongs to the YciI family.

411154:GFO RS06095
gene id: 411154:GFO_RS06095
uniprot id: A0M0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

411154:GFO RS01835
gene id: 411154:GFO_RS01835
uniprot id: A0LYC4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

411154:GFO RS01515
gene id: 411154:GFO_RS01515
uniprot id: A0LY54
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

411154:GFO RS00255
gene id: 411154:GFO_RS00255
uniprot id: A0LXE7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

411154:GFO RS14115
gene id: 411154:GFO_RS14115
uniprot id: A0M5P6
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

411154:GFO RS13030
gene id: 411154:GFO_RS13030
uniprot id: A0M524
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

411154:GFO RS00060
gene id: 411154:GFO_RS00060
uniprot id: A0LXA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

411154:GFO RS09570
gene id: 411154:GFO_RS09570
uniprot id: A0M306
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

411154:GFO RS01860
gene id: 411154:GFO_RS01860
uniprot id: A0LYC9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

411154:GFO RS00110
gene id: 411154:GFO_RS00110
uniprot id: A0LXC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

411154:GFO RS06745
gene id: 411154:GFO_RS06745
uniprot id: A0M1C1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

411154:GFO RS14005
gene id: 411154:GFO_RS14005
uniprot id: A0M5L9
names: Similarity
messages: Belongs to the peptidase C40 family.

411154:GFO RS07620
gene id: 411154:GFO_RS07620
uniprot id: A0M1V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

411154:GFO RS10815
gene id: 411154:GFO_RS10815
uniprot id: A0M3R7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

411154:GFO RS12880
gene id: 411154:GFO_RS12880
uniprot id: A0M4Z3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS13065
gene id: 411154:GFO_RS13065
uniprot id: A0M531
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS15720
gene id: 411154:GFO_RS15720
uniprot id: A0M6M9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

411154:GFO RS00665
gene id: 411154:GFO_RS00665
uniprot id: A0LXM9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

411154:GFO RS12465
gene id: 411154:GFO_RS12465
uniprot id: A0M4Q7
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS02565
gene id: 411154:GFO_RS02565
uniprot id: A0LYT0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

411154:GFO RS12810
gene id: 411154:GFO_RS12810
uniprot id: A0M4Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

411154:GFO RS00690
gene id: 411154:GFO_RS00690
uniprot id: A0LXN4
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

411154:GFO RS07110
gene id: 411154:GFO_RS07110
uniprot id: A0M1J4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

411154:GFO RS15625
gene id: 411154:GFO_RS15625
uniprot id: A0M6K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

411154:GFO RS16155
gene id: 411154:GFO_RS16155
uniprot id: A0M6W9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

411154:GFO RS15630
gene id: 411154:GFO_RS15630
uniprot id: A0M6L1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

411154:GFO RS11920
gene id: 411154:GFO_RS11920
uniprot id: A0M4E1
names: Subcellular Location Annotation
messages: Nucleus

411154:GFO RS05045
gene id: 411154:GFO_RS05045
uniprot id: A0M0A3
names: Similarity
messages: Belongs to the CarB family.

411154:GFO RS05610
gene id: 411154:GFO_RS05610
uniprot id: A0M0M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

411154:GFO RS02185
gene id: 411154:GFO_RS02185
uniprot id: A0LYK0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

411154:GFO RS14415
gene id: 411154:GFO_RS14415
uniprot id: A0M5V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

411154:GFO RS13180
gene id: 411154:GFO_RS13180
uniprot id: A0M556
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

411154:GFO RS00875
gene id: 411154:GFO_RS00875
uniprot id: A0LXS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

411154:GFO RS06845
gene id: 411154:GFO_RS06845
uniprot id: A0M1E0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

411154:GFO RS11270
gene id: 411154:GFO_RS11270
uniprot id: A0M405
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

411154:GFO RS02765
gene id: 411154:GFO_RS02765
uniprot id: A0LYX0
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS14295
gene id: 411154:GFO_RS14295
uniprot id: A0M5T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

411154:GFO RS04485
gene id: 411154:GFO_RS04485
uniprot id: A0LZY7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

411154:GFO RS10540
gene id: 411154:GFO_RS10540
uniprot id: A0M3K8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

411154:GFO RS16965
gene id: 411154:GFO_RS16965
uniprot id: A0M7D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

411154:GFO RS15970
gene id: 411154:GFO_RS15970
uniprot id: A0M6T1
names: Similarity
messages: Belongs to the pyruvate kinase family.

411154:GFO RS15295
gene id: 411154:GFO_RS15295
uniprot id: A0M6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

411154:GFO RS11850
gene id: 411154:GFO_RS11850
uniprot id: A0M4C4
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS05190
gene id: 411154:GFO_RS05190
uniprot id: A0M0D2
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS15565
gene id: 411154:GFO_RS15565
uniprot id: A0M6J8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

411154:GFO RS02525
gene id: 411154:GFO_RS02525
uniprot id: A0LYS1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

411154:GFO RS11305
gene id: 411154:GFO_RS11305
uniprot id: A0M412
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS17905
gene id: 411154:GFO_RS17905
uniprot id: A0LY20
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

411154:GFO RS12745
gene id: 411154:GFO_RS12745
uniprot id: A0M4W7
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

411154:GFO RS00520
gene id: 411154:GFO_RS00520
uniprot id: A0LXJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

411154:GFO RS13960
gene id: 411154:GFO_RS13960
uniprot id: A0M5L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS05685
gene id: 411154:GFO_RS05685
uniprot id: A0M0P6
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS00250
gene id: 411154:GFO_RS00250
uniprot id: A0LXE6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

411154:GFO RS06605
gene id: 411154:GFO_RS06605
uniprot id: A0M194
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

411154:GFO RS05250
gene id: 411154:GFO_RS05250
uniprot id: A0M0E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

411154:GFO RS16935
gene id: 411154:GFO_RS16935
uniprot id: A0M7D3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

411154:GFO RS00185
gene id: 411154:GFO_RS00185
uniprot id: A0LXD4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

411154:GFO RS15855
gene id: 411154:GFO_RS15855
uniprot id: A0M6Q7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

411154:GFO RS03330
gene id: 411154:GFO_RS03330
uniprot id: A0LZ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

411154:GFO RS16730
gene id: 411154:GFO_RS16730
uniprot id: A0M790
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS04575
gene id: 411154:GFO_RS04575
uniprot id: A0M007
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

411154:GFO RS15780
gene id: 411154:GFO_RS15780
uniprot id: A0M6P1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

411154:GFO RS16675
gene id: 411154:GFO_RS16675
uniprot id: A0M779
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

411154:GFO RS13255
gene id: 411154:GFO_RS13255
uniprot id: A0M572
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

411154:GFO RS08485
gene id: 411154:GFO_RS08485
uniprot id: A0M2D3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

411154:GFO RS06285
gene id: 411154:GFO_RS06285
uniprot id: A0M128
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS03050
gene id: 411154:GFO_RS03050
uniprot id: A0LZ23
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

411154:GFO RS12595
gene id: 411154:GFO_RS12595
uniprot id: A0M4T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

411154:GFO RS11775
gene id: 411154:GFO_RS11775
uniprot id: A0M4B0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

411154:GFO RS10490
gene id: 411154:GFO_RS10490
uniprot id: A0M3J8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

411154:GFO RS13260
gene id: 411154:GFO_RS13260
uniprot id: A0M573
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

411154:GFO RS08700
gene id: 411154:GFO_RS08700
uniprot id: A0M2H8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

411154:GFO RS05170
gene id: 411154:GFO_RS05170
uniprot id: A0M0C8
names: Similarity
messages: Belongs to the DEAD box helicase family.

411154:GFO RS09245
gene id: 411154:GFO_RS09245
uniprot id: A0M2T8
names: Similarity
messages: Belongs to the threonine synthase family.

411154:GFO RS03125
gene id: 411154:GFO_RS03125
uniprot id: A0LZ39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

411154:GFO RS16200
gene id: 411154:GFO_RS16200
uniprot id: A0M6X9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

411154:GFO RS12665
gene id: 411154:GFO_RS12665
uniprot id: A0M4V1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS06185
gene id: 411154:GFO_RS06185
uniprot id: A0M105
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

411154:GFO RS02585
gene id: 411154:GFO_RS02585
uniprot id: A0LYT4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

411154:GFO RS15095
gene id: 411154:GFO_RS15095
uniprot id: A0M6A3
names: Similarity
messages: Belongs to the DtxR/MntR family.

411154:GFO RS02805
gene id: 411154:GFO_RS02805
uniprot id: A0LYX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

411154:GFO RS14225
gene id: 411154:GFO_RS14225
uniprot id: A0M5R6
names: Similarity
messages: Belongs to the arginase family.

411154:GFO RS06090
gene id: 411154:GFO_RS06090
uniprot id: A0M0Y4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

411154:GFO RS16040
gene id: 411154:GFO_RS16040
uniprot id: A0M6U5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

411154:GFO RS02340
gene id: 411154:GFO_RS02340
uniprot id: A0LYN2
names: Similarity
messages: Belongs to the P(II) protein family.

411154:GFO RS14550
gene id: 411154:GFO_RS14550
uniprot id: A0M5Z0
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13085
gene id: 411154:GFO_RS13085
uniprot id: A0M535
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

411154:GFO RS16770
gene id: 411154:GFO_RS16770
uniprot id: A0M798
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS10600
gene id: 411154:GFO_RS10600
uniprot id: A0M3M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

411154:GFO RS15410
gene id: 411154:GFO_RS15410
uniprot id: A0M6G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

411154:GFO RS10800
gene id: 411154:GFO_RS10800
uniprot id: A0M3R4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

411154:GFO RS01865
gene id: 411154:GFO_RS01865
uniprot id: A0LYD0
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS14175
gene id: 411154:GFO_RS14175
uniprot id: A0M5Q7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

411154:GFO RS12645
gene id: 411154:GFO_RS12645
uniprot id: A0M4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS11175
gene id: 411154:GFO_RS11175
uniprot id: A0M3Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

411154:GFO RS00135
gene id: 411154:GFO_RS00135
uniprot id: A0LXC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

411154:GFO RS05180
gene id: 411154:GFO_RS05180
uniprot id: A0M0D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

411154:GFO RS00595
gene id: 411154:GFO_RS00595
uniprot id: A0LXL4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

411154:GFO RS08285
gene id: 411154:GFO_RS08285
uniprot id: A0M292
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

411154:GFO RS16785
gene id: 411154:GFO_RS16785
uniprot id: A0M7A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

411154:GFO RS14240
gene id: 411154:GFO_RS14240
uniprot id: A0M5R9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

411154:GFO RS10240
gene id: 411154:GFO_RS10240
uniprot id: A0M3E7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

411154:GFO RS13840
gene id: 411154:GFO_RS13840
uniprot id: A0M5I5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

411154:GFO RS02235
gene id: 411154:GFO_RS02235
uniprot id: A0LYL0
names: Similarity
messages: Belongs to the AIR synthase family.

411154:GFO RS10960
gene id: 411154:GFO_RS10960
uniprot id: A0M3U6
names: Similarity
messages: Belongs to the glutamate synthase family.

411154:GFO RS04940
gene id: 411154:GFO_RS04940
uniprot id: A0M081
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS01295
gene id: 411154:GFO_RS01295
uniprot id: A0LY09
names: Cofactor
messages: Binds 1 zinc ion per subunit.

411154:GFO RS16715
gene id: 411154:GFO_RS16715
uniprot id: A0M787
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

411154:GFO RS03025
gene id: 411154:GFO_RS03025
uniprot id: A0LZ18
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

411154:GFO RS10570
gene id: 411154:GFO_RS10570
uniprot id: A0M3L5
names: Similarity
messages: Belongs to the CinA family.

411154:GFO RS10845
gene id: 411154:GFO_RS10845
uniprot id: A0M3S3
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS03775
gene id: 411154:GFO_RS03775
uniprot id: A0LZH6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

411154:GFO RS13435
gene id: 411154:GFO_RS13435
uniprot id: A0M5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS07400
gene id: 411154:GFO_RS07400
uniprot id: A0M1Q5
names: Subcellular Location Annotation
messages: Cytoplasm

411154:GFO RS13630
gene id: 411154:GFO_RS13630
uniprot id: A0M5E8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

411154:GFO RS10665
gene id: 411154:GFO_RS10665
uniprot id: A0M3N6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

411154:GFO RS08300
gene id: 411154:GFO_RS08300
uniprot id: A0M295
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

411154:GFO RS13450
gene id: 411154:GFO_RS13450
uniprot id: A0M5B2
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS15050
gene id: 411154:GFO_RS15050
uniprot id: A0M693
names: Similarity
messages: Belongs to the NodU/CmcH family.

411154:GFO RS01505
gene id: 411154:GFO_RS01505
uniprot id: A0LY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

411154:GFO RS16185
gene id: 411154:GFO_RS16185
uniprot id: A0M6X6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

411154:GFO RS02455
gene id: 411154:GFO_RS02455
uniprot id: A0LYQ5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

411154:GFO RS11165
gene id: 411154:GFO_RS11165
uniprot id: A0M3Y7
names: Similarity
messages: Belongs to the DinB family.

411154:GFO RS13045
gene id: 411154:GFO_RS13045
uniprot id: A0M527
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

411154:GFO RS05215
gene id: 411154:GFO_RS05215
uniprot id: A0M0D7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

411154:GFO RS05535
gene id: 411154:GFO_RS05535
uniprot id: A0M0L2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

411154:GFO RS13455
gene id: 411154:GFO_RS13455
uniprot id: A0M5B3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

411154:GFO RS09115
gene id: 411154:GFO_RS09115
uniprot id: A0M2R0
names: Similarity
messages: Belongs to the peptidase U62 family.

411154:GFO RS08510
gene id: 411154:GFO_RS08510
uniprot id: A0M2D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

411154:GFO RS00760
gene id: 411154:GFO_RS00760
uniprot id: A0LXP8
names: Similarity
messages: Belongs to the universal stress protein A family.

411154:GFO RS00970
gene id: 411154:GFO_RS00970
uniprot id: A0LXU3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

411154:GFO RS01870
gene id: 411154:GFO_RS01870
uniprot id: A0LYD1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

411154:GFO RS02605
gene id: 411154:GFO_RS02605
uniprot id: A0LYT8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

411154:GFO RS08470
gene id: 411154:GFO_RS08470
uniprot id: A0M2D0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

411154:GFO RS14380
gene id: 411154:GFO_RS14380
uniprot id: A0M5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS01325
gene id: 411154:GFO_RS01325
uniprot id: A0LY15
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

411154:GFO RS10260
gene id: 411154:GFO_RS10260
uniprot id: A0M3F1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

411154:GFO RS10705
gene id: 411154:GFO_RS10705
uniprot id: A0M3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

411154:GFO RS14440
gene id: 411154:GFO_RS14440
uniprot id: A0M5W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

411154:GFO RS09835
gene id: 411154:GFO_RS09835
uniprot id: A0M362
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS10100
gene id: 411154:GFO_RS10100
uniprot id: A0M3B7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

411154:GFO RS12030
gene id: 411154:GFO_RS12030
uniprot id: A0M4G3
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS02970
gene id: 411154:GFO_RS02970
uniprot id: A0LZ07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS15200
gene id: 411154:GFO_RS15200
uniprot id: A0M6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS14095
gene id: 411154:GFO_RS14095
uniprot id: A0M5P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

411154:GFO RS16530
gene id: 411154:GFO_RS16530
uniprot id: A0M747
names: Similarity
messages: Belongs to the ribF family.

411154:GFO RS05660
gene id: 411154:GFO_RS05660
uniprot id: A0M0P0
names: Similarity
messages: Belongs to the universal stress protein A family.

411154:GFO RS09585
gene id: 411154:GFO_RS09585
uniprot id: A0M309
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

411154:GFO RS11135
gene id: 411154:GFO_RS11135
uniprot id: A0M3Y1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

411154:GFO RS00350
gene id: 411154:GFO_RS00350
uniprot id: A0LXG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

411154:GFO RS09865
gene id: 411154:GFO_RS09865
uniprot id: A0M368
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS03810
gene id: 411154:GFO_RS03810
uniprot id: A0LZI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

411154:GFO RS12860
gene id: 411154:GFO_RS12860
uniprot id: A0M4Z1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

411154:GFO RS07970
gene id: 411154:GFO_RS07970
uniprot id: A0M223
names: Similarity
messages: Belongs to the sulfatase family.

411154:GFO RS03335
gene id: 411154:GFO_RS03335
uniprot id: A0LZ84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

411154:GFO RS00425
gene id: 411154:GFO_RS00425
uniprot id: A0LXI1
names: Similarity
messages: Belongs to the asparaginase 1 family.

411154:GFO RS00515
gene id: 411154:GFO_RS00515
uniprot id: A0LXJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

411154:GFO RS17200
gene id: 411154:GFO_RS17200
uniprot id: A0LY74
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

411154:GFO RS15080
gene id: 411154:GFO_RS15080
uniprot id: A0M6A0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

411154:GFO RS16370
gene id: 411154:GFO_RS16370
uniprot id: A0M712
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

411154:GFO RS14290
gene id: 411154:GFO_RS14290
uniprot id: A0M5T0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

411154:GFO RS05450
gene id: 411154:GFO_RS05450
uniprot id: A0M0J1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

411154:GFO RS07160
gene id: 411154:GFO_RS07160
uniprot id: A0M1K4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

411154:GFO RS15690
gene id: 411154:GFO_RS15690
uniprot id: A0M6M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

411154:GFO RS06480
gene id: 411154:GFO_RS06480
uniprot id: A0M169
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

411154:GFO RS15885
gene id: 411154:GFO_RS15885
uniprot id: A0M6R5
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS01925
gene id: 411154:GFO_RS01925
uniprot id: A0LYE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

411154:GFO RS13160
gene id: 411154:GFO_RS13160
uniprot id: A0M552
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

411154:GFO RS02120
gene id: 411154:GFO_RS02120
uniprot id: A0LYI5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

411154:GFO RS13530
gene id: 411154:GFO_RS13530
uniprot id: A0M5C8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS00130
gene id: 411154:GFO_RS00130
uniprot id: A0LXC4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

411154:GFO RS06535
gene id: 411154:GFO_RS06535
uniprot id: A0M180
names: Subcellular Location Annotation
messages: Cytoplasm

411154:GFO RS13360
gene id: 411154:GFO_RS13360
uniprot id: A0M593
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

411154:GFO RS09650
gene id: 411154:GFO_RS09650
uniprot id: A0M324
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS01825
gene id: 411154:GFO_RS01825
uniprot id: A0LYC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

411154:GFO RS02165
gene id: 411154:GFO_RS02165
uniprot id: A0LYJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

411154:GFO RS02870
gene id: 411154:GFO_RS02870
uniprot id: A0LYZ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

411154:GFO RS09200
gene id: 411154:GFO_RS09200
uniprot id: A0M2S9
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

411154:GFO RS12935
gene id: 411154:GFO_RS12935
uniprot id: A0M505
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

411154:GFO RS13275
gene id: 411154:GFO_RS13275
uniprot id: A0M576
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

411154:GFO RS09795
gene id: 411154:GFO_RS09795
uniprot id: A0M354
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

411154:GFO RS13040
gene id: 411154:GFO_RS13040
uniprot id: A0M526
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

411154:GFO RS03825
gene id: 411154:GFO_RS03825
uniprot id: A0LZI6
names: Similarity
messages: Belongs to the ParB family.

411154:GFO RS07410
gene id: 411154:GFO_RS07410
uniprot id: A0M1Q7
names: Subcellular Location Annotation
messages: Cytoplasm

411154:GFO RS17105
gene id: 411154:GFO_RS17105
uniprot id: A0M7G7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

411154:GFO RS15575
gene id: 411154:GFO_RS15575
uniprot id: A0M6K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

411154:GFO RS16740
gene id: 411154:GFO_RS16740
uniprot id: A0M792
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

411154:GFO RS09180
gene id: 411154:GFO_RS09180
uniprot id: A0M2S4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

411154:GFO RS11105
gene id: 411154:GFO_RS11105
uniprot id: A0M3X6
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS03860
gene id: 411154:GFO_RS03860
uniprot id: A0LZJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

411154:GFO RS03555
gene id: 411154:GFO_RS03555
uniprot id: A0LZD2
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS06885
gene id: 411154:GFO_RS06885
uniprot id: A0M1E8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS08590
gene id: 411154:GFO_RS08590
uniprot id: A0M2F4
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

411154:GFO RS03735
gene id: 411154:GFO_RS03735
uniprot id: A0LZG8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

411154:GFO RS00200
gene id: 411154:GFO_RS00200
uniprot id: A0LXD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

411154:GFO RS04500
gene id: 411154:GFO_RS04500
uniprot id: A0LZZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

411154:GFO RS16050
gene id: 411154:GFO_RS16050
uniprot id: A0M6U7
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS01805
gene id: 411154:GFO_RS01805
uniprot id: A0LYB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

411154:GFO RS05825
gene id: 411154:GFO_RS05825
uniprot id: A0M0S7
names: Similarity
messages: Belongs to the glutamate synthase family.

411154:GFO RS05220
gene id: 411154:GFO_RS05220
uniprot id: A0M0D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

411154:GFO RS16535
gene id: 411154:GFO_RS16535
uniprot id: A0M748
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS07030
gene id: 411154:GFO_RS07030
uniprot id: A0M1H7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS05640
gene id: 411154:GFO_RS05640
uniprot id: A0M0N5
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS14715
gene id: 411154:GFO_RS14715
uniprot id: A0M626
names: Similarity
messages: Belongs to the SufE family.

411154:GFO RS01935
gene id: 411154:GFO_RS01935
uniprot id: A0LYE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

411154:GFO RS03280
gene id: 411154:GFO_RS03280
uniprot id: A0LZ73
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

411154:GFO RS05145
gene id: 411154:GFO_RS05145
uniprot id: A0M0C3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

411154:GFO RS16445
gene id: 411154:GFO_RS16445
uniprot id: A0M727
names: Similarity
messages: Belongs to the peptidase S41A family.

411154:GFO RS13290
gene id: 411154:GFO_RS13290
uniprot id: A0M579
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

411154:GFO RS15155
gene id: 411154:GFO_RS15155
uniprot id: A0M6B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

411154:GFO RS00610
gene id: 411154:GFO_RS00610
uniprot id: A0LXL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

411154:GFO RS16955
gene id: 411154:GFO_RS16955
uniprot id: A0M7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

411154:GFO RS00165
gene id: 411154:GFO_RS00165
uniprot id: A0LXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS09230
gene id: 411154:GFO_RS09230
uniprot id: A0M2T5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

411154:GFO RS16820
gene id: 411154:GFO_RS16820
uniprot id: A0M7A8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

411154:GFO RS13780
gene id: 411154:GFO_RS13780
uniprot id: A0M5H3
names: Similarity
messages: Belongs to the SusD family.

411154:GFO RS08355
gene id: 411154:GFO_RS08355
uniprot id: A0M2A6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

411154:GFO RS10560
gene id: 411154:GFO_RS10560
uniprot id: A0M3L3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

411154:GFO RS03680
gene id: 411154:GFO_RS03680
uniprot id: A0LZF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

411154:GFO RS05870
gene id: 411154:GFO_RS05870
uniprot id: A0M0T9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS14765
gene id: 411154:GFO_RS14765
uniprot id: A0M637
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

411154:GFO RS03385
gene id: 411154:GFO_RS03385
uniprot id: A0LZ94
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS04705
gene id: 411154:GFO_RS04705
uniprot id: A0M034
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13375
gene id: 411154:GFO_RS13375
uniprot id: A0M596
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

411154:GFO RS13295
gene id: 411154:GFO_RS13295
uniprot id: A0M580
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

411154:GFO RS00965
gene id: 411154:GFO_RS00965
uniprot id: A0LXU2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

411154:GFO RS10350
gene id: 411154:GFO_RS10350
uniprot id: A0M3G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

411154:GFO RS01735
gene id: 411154:GFO_RS01735
uniprot id: A0LYA3
names: Similarity
messages: Belongs to the SusD family.

411154:GFO RS07555
gene id: 411154:GFO_RS07555
uniprot id: A0M1T8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

411154:GFO RS17145
gene id: 411154:GFO_RS17145
uniprot id: A0M7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

411154:GFO RS03035
gene id: 411154:GFO_RS03035
uniprot id: A0LZ20
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

411154:GFO RS15070
gene id: 411154:GFO_RS15070
uniprot id: A0M698
names: Similarity
messages: Belongs to the SCO1/2 family.

411154:GFO RS10595
gene id: 411154:GFO_RS10595
uniprot id: A0M3M1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

411154:GFO RS02720
gene id: 411154:GFO_RS02720
uniprot id: A0LYW1
names: Similarity
messages: Belongs to the asparagine synthetase family.

411154:GFO RS10755
gene id: 411154:GFO_RS10755
uniprot id: A0M3Q4
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS06045
gene id: 411154:GFO_RS06045
uniprot id: A0M0X5
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS03560
gene id: 411154:GFO_RS03560
uniprot id: A0LZD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

411154:GFO RS02395
gene id: 411154:GFO_RS02395
uniprot id: A0LYP3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

411154:GFO RS13405
gene id: 411154:GFO_RS13405
uniprot id: A0M5A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

411154:GFO RS07140
gene id: 411154:GFO_RS07140
uniprot id: A0M1K0
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

411154:GFO RS14140
gene id: 411154:GFO_RS14140
uniprot id: A0M5Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

411154:GFO RS11215
gene id: 411154:GFO_RS11215
uniprot id: A0M3Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

411154:GFO RS10710
gene id: 411154:GFO_RS10710
uniprot id: A0M3P5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

411154:GFO RS16710
gene id: 411154:GFO_RS16710
uniprot id: A0M786
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

411154:GFO RS16920
gene id: 411154:GFO_RS16920
uniprot id: A0M7D0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

411154:GFO RS06925
gene id: 411154:GFO_RS06925
uniprot id: A0M1F6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

411154:GFO RS15375
gene id: 411154:GFO_RS15375
uniprot id: A0M6G0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

411154:GFO RS08270
gene id: 411154:GFO_RS08270
uniprot id: A0M289
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

411154:GFO RS03300
gene id: 411154:GFO_RS03300
uniprot id: A0LZ77
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

411154:GFO RS13265
gene id: 411154:GFO_RS13265
uniprot id: A0M574
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

411154:GFO RS04930
gene id: 411154:GFO_RS04930
uniprot id: A0M079
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

411154:GFO RS12015
gene id: 411154:GFO_RS12015
uniprot id: A0M4G0
names: Similarity
messages: Belongs to the DinB family.

411154:GFO RS15475
gene id: 411154:GFO_RS15475
uniprot id: A0M6I0
names: Similarity
messages: Belongs to the GARS family.

411154:GFO RS07500
gene id: 411154:GFO_RS07500
uniprot id: A0M1S7
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13955
gene id: 411154:GFO_RS13955
uniprot id: A0M5K9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

411154:GFO RS03185
gene id: 411154:GFO_RS03185
uniprot id: A0LZ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

411154:GFO RS06980
gene id: 411154:GFO_RS06980
uniprot id: A0M1G7
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13545
gene id: 411154:GFO_RS13545
uniprot id: A0M5D1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS15240
gene id: 411154:GFO_RS15240
uniprot id: A0M6D2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

411154:GFO RS08180
gene id: 411154:GFO_RS08180
uniprot id: A0M270
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

411154:GFO RS10465
gene id: 411154:GFO_RS10465
uniprot id: A0M3J3
names: Similarity
messages: Belongs to the peptidase S8 family.

411154:GFO RS12575
gene id: 411154:GFO_RS12575
uniprot id: A0M4T1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

411154:GFO RS08755
gene id: 411154:GFO_RS08755
uniprot id: A0M2J0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

411154:GFO RS10035
gene id: 411154:GFO_RS10035
uniprot id: A0M3A4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

411154:GFO RS13990
gene id: 411154:GFO_RS13990
uniprot id: A0M5L6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

411154:GFO RS16520
gene id: 411154:GFO_RS16520
uniprot id: A0M745
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

411154:GFO RS08210
gene id: 411154:GFO_RS08210
uniprot id: A0M277
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS16765
gene id: 411154:GFO_RS16765
uniprot id: A0M797
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

411154:GFO RS09325
gene id: 411154:GFO_RS09325
uniprot id: A0M2V5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

411154:GFO RS03055
gene id: 411154:GFO_RS03055
uniprot id: A0LZ24
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

411154:GFO RS08325
gene id: 411154:GFO_RS08325
uniprot id: A0M2A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

411154:GFO RS15490
gene id: 411154:GFO_RS15490
uniprot id: A0M6I3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

411154:GFO RS14285
gene id: 411154:GFO_RS14285
uniprot id: A0M5S9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

411154:GFO RS07045
gene id: 411154:GFO_RS07045
uniprot id: A0M1I0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

411154:GFO RS10440
gene id: 411154:GFO_RS10440
uniprot id: A0M3I8
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

411154:GFO RS12965
gene id: 411154:GFO_RS12965
uniprot id: A0M511
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS05050
gene id: 411154:GFO_RS05050
uniprot id: A0M0A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

411154:GFO RS07715
gene id: 411154:GFO_RS07715
uniprot id: A0M1X1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS10270
gene id: 411154:GFO_RS10270
uniprot id: A0M3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

411154:GFO RS04885
gene id: 411154:GFO_RS04885
uniprot id: A0M070
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.

411154:GFO RS15820
gene id: 411154:GFO_RS15820
uniprot id: A0M6P9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

411154:GFO RS01920
gene id: 411154:GFO_RS01920
uniprot id: A0LYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

411154:GFO RS04665
gene id: 411154:GFO_RS04665
uniprot id: A0M026
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

411154:GFO RS05940
gene id: 411154:GFO_RS05940
uniprot id: A0M0V3
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS16330
gene id: 411154:GFO_RS16330
uniprot id: A0M704
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

411154:GFO RS13250
gene id: 411154:GFO_RS13250
uniprot id: A0M571
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

411154:GFO RS01520
gene id: 411154:GFO_RS01520
uniprot id: A0LY55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

411154:GFO RS03375
gene id: 411154:GFO_RS03375
uniprot id: A0LZ92
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS08500
gene id: 411154:GFO_RS08500
uniprot id: A0M2D6
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

411154:GFO RS08290
gene id: 411154:GFO_RS08290
uniprot id: A0M293
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

411154:GFO RS08375
gene id: 411154:GFO_RS08375
uniprot id: A0M2B1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS16760
gene id: 411154:GFO_RS16760
uniprot id: A0M796
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

411154:GFO RS00555
gene id: 411154:GFO_RS00555
uniprot id: A0LXK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS10390
gene id: 411154:GFO_RS10390
uniprot id: A0M3H7
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS16175
gene id: 411154:GFO_RS16175
uniprot id: A0M6X4
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

411154:GFO RS16780
gene id: 411154:GFO_RS16780
uniprot id: A0M7A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

411154:GFO RS05565
gene id: 411154:GFO_RS05565
uniprot id: A0M0L8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

411154:GFO RS09330
gene id: 411154:GFO_RS09330
uniprot id: A0M2V6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

411154:GFO RS15765
gene id: 411154:GFO_RS15765
uniprot id: A0M6N7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

411154:GFO RS03750
gene id: 411154:GFO_RS03750
uniprot id: A0LZH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

411154:GFO RS07185
gene id: 411154:GFO_RS07185
uniprot id: A0M1L0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

411154:GFO RS01965
gene id: 411154:GFO_RS01965
uniprot id: A0LYF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

411154:GFO RS16735
gene id: 411154:GFO_RS16735
uniprot id: A0M791
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

411154:GFO RS01060
gene id: 411154:GFO_RS01060
uniprot id: A0LXW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS10530
gene id: 411154:GFO_RS10530
uniprot id: A0M3K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

411154:GFO RS05240
gene id: 411154:GFO_RS05240
uniprot id: A0M0E2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS04635
gene id: 411154:GFO_RS04635
uniprot id: A0M020
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13485
gene id: 411154:GFO_RS13485
uniprot id: A0M5B9
names: Similarity
messages: Belongs to the UPF0758 family.

411154:GFO RS02505
gene id: 411154:GFO_RS02505
uniprot id: A0LYR6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS11025
gene id: 411154:GFO_RS11025
uniprot id: A0M3V9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

411154:GFO RS05880
gene id: 411154:GFO_RS05880
uniprot id: A0M0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS08160
gene id: 411154:GFO_RS08160
uniprot id: A0M266
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

411154:GFO RS07105
gene id: 411154:GFO_RS07105
uniprot id: A0M1J3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

411154:GFO RS09755
gene id: 411154:GFO_RS09755
uniprot id: A0M345
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

411154:GFO RS15210
gene id: 411154:GFO_RS15210
uniprot id: A0M6C6
names: Subunit
messages: Homodimer.

411154:GFO RS09555
gene id: 411154:GFO_RS09555
uniprot id: A0M303
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

411154:GFO RS01115
gene id: 411154:GFO_RS01115
uniprot id: A0LXX3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

411154:GFO RS03550
gene id: 411154:GFO_RS03550
uniprot id: A0LZD1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

411154:GFO RS04805
gene id: 411154:GFO_RS04805
uniprot id: A0M054
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS17100
gene id: 411154:GFO_RS17100
uniprot id: A0M7G6
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

411154:GFO RS13415
gene id: 411154:GFO_RS13415
uniprot id: A0M5A4
names: Similarity
messages: Belongs to the SusD family.

411154:GFO RS01405
gene id: 411154:GFO_RS01405
uniprot id: A0LY31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

411154:GFO RS02365
gene id: 411154:GFO_RS02365
uniprot id: A0LYN7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

411154:GFO RS08240
gene id: 411154:GFO_RS08240
uniprot id: A0M283
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

411154:GFO RS06750
gene id: 411154:GFO_RS06750
uniprot id: A0M1C2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

411154:GFO RS03060
gene id: 411154:GFO_RS03060
uniprot id: A0LZ26
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

411154:GFO RS03390
gene id: 411154:GFO_RS03390
uniprot id: A0LZ95
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS01160
gene id: 411154:GFO_RS01160
uniprot id: A0LXY3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS16485
gene id: 411154:GFO_RS16485
uniprot id: A0M734
names: Similarity
messages: Belongs to the AHA1 family.

411154:GFO RS02780
gene id: 411154:GFO_RS02780
uniprot id: A0LYX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

411154:GFO RS14865
gene id: 411154:GFO_RS14865
uniprot id: A0M657
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS07935
gene id: 411154:GFO_RS07935
uniprot id: A0M217
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

411154:GFO RS00775
gene id: 411154:GFO_RS00775
uniprot id: A0LXQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

411154:GFO RS15190
gene id: 411154:GFO_RS15190
uniprot id: A0M6C2
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

411154:GFO RS02210
gene id: 411154:GFO_RS02210
uniprot id: A0LYK5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

411154:GFO RS13060
gene id: 411154:GFO_RS13060
uniprot id: A0M530
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

411154:GFO RS08025
gene id: 411154:GFO_RS08025
uniprot id: A0M235
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

411154:GFO RS04960
gene id: 411154:GFO_RS04960
uniprot id: A0M085
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS02790
gene id: 411154:GFO_RS02790
uniprot id: A0LYX5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

411154:GFO RS11170
gene id: 411154:GFO_RS11170
uniprot id: A0M3Y8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

411154:GFO RS00045
gene id: 411154:GFO_RS00045
uniprot id: A0LXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS04045
gene id: 411154:GFO_RS04045
uniprot id: A0LZM9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

411154:GFO RS02335
gene id: 411154:GFO_RS02335
uniprot id: A0LYN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

411154:GFO RS03080
gene id: 411154:GFO_RS03080
uniprot id: A0LZ30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

411154:GFO RS04900
gene id: 411154:GFO_RS04900
uniprot id: A0M073
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

411154:GFO RS13350
gene id: 411154:GFO_RS13350
uniprot id: A0M591
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

411154:GFO RS13025
gene id: 411154:GFO_RS13025
uniprot id: A0M523
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

411154:GFO RS15315
gene id: 411154:GFO_RS15315
uniprot id: A0M6E8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

411154:GFO RS11115
gene id: 411154:GFO_RS11115
uniprot id: A0M3X8
names: Similarity
messages: Belongs to the RelE toxin family.

411154:GFO RS15605
gene id: 411154:GFO_RS15605
uniprot id: A0M6K6
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS06650
gene id: 411154:GFO_RS06650
uniprot id: A0M1A3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

411154:GFO RS13790
gene id: 411154:GFO_RS13790
uniprot id: A0M5H5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

411154:GFO RS04825
gene id: 411154:GFO_RS04825
uniprot id: A0M058
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS07820
gene id: 411154:GFO_RS07820
uniprot id: A0M1Z2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

411154:GFO RS10645
gene id: 411154:GFO_RS10645
uniprot id: A0M3N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS06445
gene id: 411154:GFO_RS06445
uniprot id: A0M160
names: Similarity
messages: Belongs to the SusD family.

411154:GFO RS05920
gene id: 411154:GFO_RS05920
uniprot id: A0M0U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

411154:GFO RS15135
gene id: 411154:GFO_RS15135
uniprot id: A0M6B1
names: Similarity
messages: Belongs to the FPG family.

411154:GFO RS08790
gene id: 411154:GFO_RS08790
uniprot id: A0M2J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

411154:GFO RS06450
gene id: 411154:GFO_RS06450
uniprot id: A0M161
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS05410
gene id: 411154:GFO_RS05410
uniprot id: A0M0I3
names: Similarity
messages: Belongs to the SusD family.

411154:GFO RS15775
gene id: 411154:GFO_RS15775
uniprot id: A0M6P0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

411154:GFO RS14730
gene id: 411154:GFO_RS14730
uniprot id: A0M629
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

411154:GFO RS06175
gene id: 411154:GFO_RS06175
uniprot id: A0M103
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

411154:GFO RS08650
gene id: 411154:GFO_RS08650
uniprot id: A0M2G6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

411154:GFO RS05175
gene id: 411154:GFO_RS05175
uniprot id: A0M0C9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

411154:GFO RS11830
gene id: 411154:GFO_RS11830
uniprot id: A0M4C0
names: Similarity
messages: Belongs to the Skp family.

411154:GFO RS00475
gene id: 411154:GFO_RS00475
uniprot id: A0LXJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS02075
gene id: 411154:GFO_RS02075
uniprot id: A0LYH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

411154:GFO RS10060
gene id: 411154:GFO_RS10060
uniprot id: A0M3A9
names: Similarity
messages: Belongs to the SusD family.

411154:GFO RS15835
gene id: 411154:GFO_RS15835
uniprot id: A0M6Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

411154:GFO RS05015
gene id: 411154:GFO_RS05015
uniprot id: A0M097
names: Similarity
messages: Belongs to the pirin family.

411154:GFO RS01765
gene id: 411154:GFO_RS01765
uniprot id: A0LYA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

411154:GFO RS08030
gene id: 411154:GFO_RS08030
uniprot id: A0M236
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS03175
gene id: 411154:GFO_RS03175
uniprot id: A0LZ49
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

411154:GFO RS03235
gene id: 411154:GFO_RS03235
uniprot id: A0LZ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

411154:GFO RS14525
gene id: 411154:GFO_RS14525
uniprot id: A0M5Y5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

411154:GFO RS10510
gene id: 411154:GFO_RS10510
uniprot id: A0M3K2
names: Similarity
messages: Belongs to the BshC family.

411154:GFO RS14595
gene id: 411154:GFO_RS14595
uniprot id: A0M5Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

411154:GFO RS10855
gene id: 411154:GFO_RS10855
uniprot id: A0M3S5
names: Similarity
messages: Belongs to the CIA30 family.

411154:GFO RS15610
gene id: 411154:GFO_RS15610
uniprot id: A0M6K7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

411154:GFO RS04875
gene id: 411154:GFO_RS04875
uniprot id: A0M068
names: Subcellular Location Annotation
messages: Secreted

411154:GFO RS15810
gene id: 411154:GFO_RS15810
uniprot id: A0M6P7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS09670
gene id: 411154:GFO_RS09670
uniprot id: A0M328
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS12555
gene id: 411154:GFO_RS12555
uniprot id: A0M4S7
names: Similarity
messages: Belongs to the nitroreductase family.

411154:GFO RS02065
gene id: 411154:GFO_RS02065
uniprot id: A0LYH0
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS05540
gene id: 411154:GFO_RS05540
uniprot id: A0M0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

411154:GFO RS10445
gene id: 411154:GFO_RS10445
uniprot id: A0M3I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

411154:GFO RS07725
gene id: 411154:GFO_RS07725
uniprot id: A0M1X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

411154:GFO RS16860
gene id: 411154:GFO_RS16860
uniprot id: A0M7B8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

411154:GFO RS13625
gene id: 411154:GFO_RS13625
uniprot id: A0M5E7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

411154:GFO RS07420
gene id: 411154:GFO_RS07420
uniprot id: A0M1Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

411154:GFO RS00540
gene id: 411154:GFO_RS00540
uniprot id: A0LXK3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

411154:GFO RS07115
gene id: 411154:GFO_RS07115
uniprot id: A0M1J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

411154:GFO RS17165
gene id: 411154:GFO_RS17165
uniprot id: A0M7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

411154:GFO RS05185
gene id: 411154:GFO_RS05185
uniprot id: A0M0D1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

411154:GFO RS01080
gene id: 411154:GFO_RS01080
uniprot id: A0LXW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

411154:GFO RS02835
gene id: 411154:GFO_RS02835
uniprot id: A0LYY4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS02785
gene id: 411154:GFO_RS02785
uniprot id: A0LYX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

411154:GFO RS03325
gene id: 411154:GFO_RS03325
uniprot id: A0LZ82
names: Similarity
messages: Belongs to the aldose epimerase family.

411154:GFO RS09215
gene id: 411154:GFO_RS09215
uniprot id: A0M2T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS15560
gene id: 411154:GFO_RS15560
uniprot id: A0M6J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

411154:GFO RS01560
gene id: 411154:GFO_RS01560
uniprot id: A0LY65
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

411154:GFO RS12580
gene id: 411154:GFO_RS12580
uniprot id: A0M4T2
names: Similarity
messages: Belongs to the TrpC family.

411154:GFO RS14995
gene id: 411154:GFO_RS14995
uniprot id: A0M683
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS15500
gene id: 411154:GFO_RS15500
uniprot id: A0M6I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

411154:GFO RS00575
gene id: 411154:GFO_RS00575
uniprot id: A0LXL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS08110
gene id: 411154:GFO_RS08110
uniprot id: A0M256
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

411154:GFO RS00670
gene id: 411154:GFO_RS00670
uniprot id: A0LXN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

411154:GFO RS02405
gene id: 411154:GFO_RS02405
uniprot id: A0LYP5
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS16865
gene id: 411154:GFO_RS16865
uniprot id: A0M7B9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

411154:GFO RS08390
gene id: 411154:GFO_RS08390
uniprot id: A0M2B4
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS16345
gene id: 411154:GFO_RS16345
uniprot id: A0M707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS09805
gene id: 411154:GFO_RS09805
uniprot id: A0M356
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

411154:GFO RS13785
gene id: 411154:GFO_RS13785
uniprot id: A0M5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS08595
gene id: 411154:GFO_RS08595
uniprot id: A0M2F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

411154:GFO RS01585
gene id: 411154:GFO_RS01585
uniprot id: A0LY71
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

411154:GFO RS03515
gene id: 411154:GFO_RS03515
uniprot id: A0LZC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

411154:GFO RS02285
gene id: 411154:GFO_RS02285
uniprot id: A0LYM0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

411154:GFO RS15165
gene id: 411154:GFO_RS15165
uniprot id: A0M6B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

411154:GFO RS13270
gene id: 411154:GFO_RS13270
uniprot id: A0M575
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

411154:GFO RS07215
gene id: 411154:GFO_RS07215
uniprot id: A0M1L6
names: Similarity
messages: Belongs to the YjiK family.

411154:GFO RS12625
gene id: 411154:GFO_RS12625
uniprot id: A0M4U3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

411154:GFO RS16140
gene id: 411154:GFO_RS16140
uniprot id: A0M6W6
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS12480
gene id: 411154:GFO_RS12480
uniprot id: A0M4R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

411154:GFO RS01040
gene id: 411154:GFO_RS01040
uniprot id: A0LXV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

411154:GFO RS14135
gene id: 411154:GFO_RS14135
uniprot id: A0M5Q0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS07635
gene id: 411154:GFO_RS07635
uniprot id: A0M1V4
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS14020
gene id: 411154:GFO_RS14020
uniprot id: A0M5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

411154:GFO RS15790
gene id: 411154:GFO_RS15790
uniprot id: A0M6P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

411154:GFO RS11180
gene id: 411154:GFO_RS11180
uniprot id: A0M3Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

411154:GFO RS08190
gene id: 411154:GFO_RS08190
uniprot id: A0M273
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS08330
gene id: 411154:GFO_RS08330
uniprot id: A0M2A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

411154:GFO RS16410
gene id: 411154:GFO_RS16410
uniprot id: A0M720
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

411154:GFO RS14975
gene id: 411154:GFO_RS14975
uniprot id: A0M679
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

411154:GFO RS12765
gene id: 411154:GFO_RS12765
uniprot id: A0M4X1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

411154:GFO RS15645
gene id: 411154:GFO_RS15645
uniprot id: A0M6L4
names: Similarity
messages: Belongs to the peptidase S41A family.

411154:GFO RS09890
gene id: 411154:GFO_RS09890
uniprot id: A0M373
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

411154:GFO RS10765
gene id: 411154:GFO_RS10765
uniprot id: A0M3Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

411154:GFO RS15660
gene id: 411154:GFO_RS15660
uniprot id: A0M6L7
names: Similarity
messages: Belongs to the peptidase S8 family.

411154:GFO RS15000
gene id: 411154:GFO_RS15000
uniprot id: A0M684
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

411154:GFO RS11275
gene id: 411154:GFO_RS11275
uniprot id: A0M406
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

411154:GFO RS04560
gene id: 411154:GFO_RS04560
uniprot id: A0M004
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

411154:GFO RS09055
gene id: 411154:GFO_RS09055
uniprot id: A0M2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

411154:GFO RS12735
gene id: 411154:GFO_RS12735
uniprot id: A0M4W5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

411154:GFO RS08060
gene id: 411154:GFO_RS08060
uniprot id: A0M242
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

411154:GFO RS10565
gene id: 411154:GFO_RS10565
uniprot id: A0M3L4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

411154:GFO RS00150
gene id: 411154:GFO_RS00150
uniprot id: A0LXC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

411154:GFO RS16560
gene id: 411154:GFO_RS16560
uniprot id: A0M754
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

411154:GFO RS10365
gene id: 411154:GFO_RS10365
uniprot id: A0M3H2
names: Similarity
messages: Belongs to the AHA1 family.

411154:GFO RS04060
gene id: 411154:GFO_RS04060
uniprot id: A0LZN2
names: Similarity
messages: Belongs to the peptidase S33 family.

411154:GFO RS13125
gene id: 411154:GFO_RS13125
uniprot id: A0M543
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS09920
gene id: 411154:GFO_RS09920
uniprot id: A0M379
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

411154:GFO RS07945
gene id: 411154:GFO_RS07945
uniprot id: A0M219
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS10000
gene id: 411154:GFO_RS10000
uniprot id: A0M397
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

411154:GFO RS07405
gene id: 411154:GFO_RS07405
uniprot id: A0M1Q5
names: Subcellular Location Annotation
messages: Cytoplasm

411154:GFO RS13320
gene id: 411154:GFO_RS13320
uniprot id: A0M585
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

411154:GFO RS02265
gene id: 411154:GFO_RS02265
uniprot id: A0LYL6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

411154:GFO RS12990
gene id: 411154:GFO_RS12990
uniprot id: A0M516
names: Similarity
messages: Belongs to the peptidase S13 family.

411154:GFO RS10110
gene id: 411154:GFO_RS10110
uniprot id: A0M3B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

411154:GFO RS15005
gene id: 411154:GFO_RS15005
uniprot id: A0M685
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

411154:GFO RS11185
gene id: 411154:GFO_RS11185
uniprot id: A0M3Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

411154:GFO RS14905
gene id: 411154:GFO_RS14905
uniprot id: A0M665
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

411154:GFO RS02950
gene id: 411154:GFO_RS02950
uniprot id: A0LZ03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

411154:GFO RS03040
gene id: 411154:GFO_RS03040
uniprot id: A0LZ21
names: Similarity
messages: Belongs to the LOG family.

411154:GFO RS03535
gene id: 411154:GFO_RS03535
uniprot id: A0LZC8
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

411154:GFO RS06945
gene id: 411154:GFO_RS06945
uniprot id: A0M1G0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

411154:GFO RS07035
gene id: 411154:GFO_RS07035
uniprot id: A0M1H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

411154:GFO RS09575
gene id: 411154:GFO_RS09575
uniprot id: A0M307
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

411154:GFO RS02850
gene id: 411154:GFO_RS02850
uniprot id: A0LYY7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

411154:GFO RS01320
gene id: 411154:GFO_RS01320
uniprot id: A0LY14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

411154:GFO RS01440
gene id: 411154:GFO_RS01440
uniprot id: A0LY38
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

411154:GFO RS01820
gene id: 411154:GFO_RS01820
uniprot id: A0LYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

411154:GFO RS01015
gene id: 411154:GFO_RS01015
uniprot id: A0LXV3
names: Similarity
messages: Belongs to the Skp family.

411154:GFO RS05290
gene id: 411154:GFO_RS05290
uniprot id: A0M0F3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

411154:GFO RS00650
gene id: 411154:GFO_RS00650
uniprot id: A0LXM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

411154:GFO RS06775
gene id: 411154:GFO_RS06775
uniprot id: A0M1C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS13915
gene id: 411154:GFO_RS13915
uniprot id: A0M5K1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

411154:GFO RS08860
gene id: 411154:GFO_RS08860
uniprot id: A0M2L2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

411154:GFO RS00480
gene id: 411154:GFO_RS00480
uniprot id: A0LXJ1
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS09250
gene id: 411154:GFO_RS09250
uniprot id: A0M2T9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS01165
gene id: 411154:GFO_RS01165
uniprot id: A0LXY4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

411154:GFO RS00935
gene id: 411154:GFO_RS00935
uniprot id: A0LXT6
names: Similarity
messages: Belongs to the SCO1/2 family.

411154:GFO RS02050
gene id: 411154:GFO_RS02050
uniprot id: A0LYG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

411154:GFO RS09170
gene id: 411154:GFO_RS09170
uniprot id: A0M2S2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

411154:GFO RS11800
gene id: 411154:GFO_RS11800
uniprot id: A0M4B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

411154:GFO RS03605
gene id: 411154:GFO_RS03605
uniprot id: A0LZE2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

411154:GFO RS08255
gene id: 411154:GFO_RS08255
uniprot id: A0M286
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS01485
gene id: 411154:GFO_RS01485
uniprot id: A0LY47
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS16605
gene id: 411154:GFO_RS16605
uniprot id: A0M764
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

411154:GFO RS06120
gene id: 411154:GFO_RS06120
uniprot id: A0M0Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS14130
gene id: 411154:GFO_RS14130
uniprot id: A0M5P9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

411154:GFO RS15030
gene id: 411154:GFO_RS15030
uniprot id: A0M690
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

411154:GFO RS14750
gene id: 411154:GFO_RS14750
uniprot id: A0M633
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

411154:GFO RS10075
gene id: 411154:GFO_RS10075
uniprot id: A0M3B2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

411154:GFO RS12685
gene id: 411154:GFO_RS12685
uniprot id: A0M4V5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

411154:GFO RS02435
gene id: 411154:GFO_RS02435
uniprot id: A0LYQ1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

411154:GFO RS01130
gene id: 411154:GFO_RS01130
uniprot id: A0LXX6
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

411154:GFO RS14070
gene id: 411154:GFO_RS14070
uniprot id: A0M5N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS08980
gene id: 411154:GFO_RS08980
uniprot id: A0M2N2
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS09525
gene id: 411154:GFO_RS09525
uniprot id: A0M2Z7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

411154:GFO RS05435
gene id: 411154:GFO_RS05435
uniprot id: A0M0I8
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13340
gene id: 411154:GFO_RS13340
uniprot id: A0M589
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

411154:GFO RS00855
gene id: 411154:GFO_RS00855
uniprot id: A0LXR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

411154:GFO RS08855
gene id: 411154:GFO_RS08855
uniprot id: A0M2L1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

411154:GFO RS06255
gene id: 411154:GFO_RS06255
uniprot id: A0M121
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

411154:GFO RS02030
gene id: 411154:GFO_RS02030
uniprot id: A0LYG3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

411154:GFO RS10230
gene id: 411154:GFO_RS10230
uniprot id: A0M3E5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

411154:GFO RS01450
gene id: 411154:GFO_RS01450
uniprot id: A0LY40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

411154:GFO RS12605
gene id: 411154:GFO_RS12605
uniprot id: A0M4T9
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

411154:GFO RS13615
gene id: 411154:GFO_RS13615
uniprot id: A0M5E5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

411154:GFO RS15390
gene id: 411154:GFO_RS15390
uniprot id: A0M6G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

411154:GFO RS13235
gene id: 411154:GFO_RS13235
uniprot id: A0M568
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

411154:GFO RS15065
gene id: 411154:GFO_RS15065
uniprot id: A0M697
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

411154:GFO RS10015
gene id: 411154:GFO_RS10015
uniprot id: A0M3A0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

411154:GFO RS16235
gene id: 411154:GFO_RS16235
uniprot id: A0M6Y6
names: Similarity
messages: Belongs to the ArsC family.

411154:GFO RS12950
gene id: 411154:GFO_RS12950
uniprot id: A0M508
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

411154:GFO RS09340
gene id: 411154:GFO_RS09340
uniprot id: A0M2V8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

411154:GFO RS05135
gene id: 411154:GFO_RS05135
uniprot id: A0M0C1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

411154:GFO RS11045
gene id: 411154:GFO_RS11045
uniprot id: A0M3W3
names: Similarity
messages: Belongs to the heat shock protein 90 family.

411154:GFO RS01915
gene id: 411154:GFO_RS01915
uniprot id: A0LYE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

411154:GFO RS07270
gene id: 411154:GFO_RS07270
uniprot id: A0M1M8
names: Similarity
messages: Belongs to the aspartokinase family.

411154:GFO RS07730
gene id: 411154:GFO_RS07730
uniprot id: A0M1X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

411154:GFO RS05615
gene id: 411154:GFO_RS05615
uniprot id: A0M0N0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

411154:GFO RS09710
gene id: 411154:GFO_RS09710
uniprot id: A0M336
names: Similarity
messages: Belongs to the LOG family.

411154:GFO RS15695
gene id: 411154:GFO_RS15695
uniprot id: A0M6M4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

411154:GFO RS00435
gene id: 411154:GFO_RS00435
uniprot id: A0LXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

411154:GFO RS07245
gene id: 411154:GFO_RS07245
uniprot id: A0M1M2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

411154:GFO RS01720
gene id: 411154:GFO_RS01720
uniprot id: A0LYA0
names: Similarity
messages: Belongs to the sulfatase family.

411154:GFO RS10590
gene id: 411154:GFO_RS10590
uniprot id: A0M3M0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

411154:GFO RS10115
gene id: 411154:GFO_RS10115
uniprot id: A0M3C0
names: Similarity
messages: Belongs to the aldose epimerase family.

411154:GFO RS12640
gene id: 411154:GFO_RS12640
uniprot id: A0M4U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

411154:GFO RS01940
gene id: 411154:GFO_RS01940
uniprot id: A0LYE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

411154:GFO RS08120
gene id: 411154:GFO_RS08120
uniprot id: A0M258
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS12530
gene id: 411154:GFO_RS12530
uniprot id: A0M4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

411154:GFO RS06740
gene id: 411154:GFO_RS06740
uniprot id: A0M1C0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

411154:GFO RS06675
gene id: 411154:GFO_RS06675
uniprot id: A0M1A8
names: Similarity
messages: Belongs to the universal stress protein A family.

411154:GFO RS10310
gene id: 411154:GFO_RS10310
uniprot id: A0M3G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS03690
gene id: 411154:GFO_RS03690
uniprot id: A0LZF9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

411154:GFO RS00035
gene id: 411154:GFO_RS00035
uniprot id: A0LXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

411154:GFO RS14025
gene id: 411154:GFO_RS14025
uniprot id: A0M5M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

411154:GFO RS16970
gene id: 411154:GFO_RS16970
uniprot id: A0M7E0
names: Similarity
messages: Belongs to the AHA1 family.

411154:GFO RS14035
gene id: 411154:GFO_RS14035
uniprot id: A0M5M5
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

411154:GFO RS03265
gene id: 411154:GFO_RS03265
uniprot id: A0LZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS09900
gene id: 411154:GFO_RS09900
uniprot id: A0M375
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

411154:GFO RS17250
gene id: 411154:GFO_RS17250
uniprot id: A0M239
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

411154:GFO RS15735
gene id: 411154:GFO_RS15735
uniprot id: A0M6N2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

411154:GFO RS02040
gene id: 411154:GFO_RS02040
uniprot id: A0LYG5
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS15100
gene id: 411154:GFO_RS15100
uniprot id: A0M6A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS00835
gene id: 411154:GFO_RS00835
uniprot id: A0LXR4
names: Similarity
messages: Belongs to the cytochrome P450 family.

411154:GFO RS09255
gene id: 411154:GFO_RS09255
uniprot id: A0M2U0
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

411154:GFO RS15940
gene id: 411154:GFO_RS15940
uniprot id: A0M6S5
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

411154:GFO RS13120
gene id: 411154:GFO_RS13120
uniprot id: A0M542
names: Similarity
messages: Belongs to the NAD synthetase family.

411154:GFO RS07385
gene id: 411154:GFO_RS07385
uniprot id: A0M1Q2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

411154:GFO RS08560
gene id: 411154:GFO_RS08560
uniprot id: A0M2E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

411154:GFO RS12955
gene id: 411154:GFO_RS12955
uniprot id: A0M509
names: Similarity
messages: Belongs to the asparagine synthetase family.

411154:GFO RS02290
gene id: 411154:GFO_RS02290
uniprot id: A0LYM1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS09860
gene id: 411154:GFO_RS09860
uniprot id: A0M367
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

411154:GFO RS15825
gene id: 411154:GFO_RS15825
uniprot id: A0M6Q0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS08990
gene id: 411154:GFO_RS08990
uniprot id: A0M2N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

411154:GFO RS13410
gene id: 411154:GFO_RS13410
uniprot id: A0M5A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS10700
gene id: 411154:GFO_RS10700
uniprot id: A0M3P3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

411154:GFO RS16795
gene id: 411154:GFO_RS16795
uniprot id: A0M7A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

411154:GFO RS08345
gene id: 411154:GFO_RS08345
uniprot id: A0M2A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

411154:GFO RS02225
gene id: 411154:GFO_RS02225
uniprot id: A0LYK8
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS00770
gene id: 411154:GFO_RS00770
uniprot id: A0LXQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

411154:GFO RS09580
gene id: 411154:GFO_RS09580
uniprot id: A0M308
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

411154:GFO RS09530
gene id: 411154:GFO_RS09530
uniprot id: A0M2Z8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

411154:GFO RS08250
gene id: 411154:GFO_RS08250
uniprot id: A0M285
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

411154:GFO RS15955
gene id: 411154:GFO_RS15955
uniprot id: A0M6S8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

411154:GFO RS16195
gene id: 411154:GFO_RS16195
uniprot id: A0M6X8
names: Similarity
messages: Belongs to the YicC/YloC family.

411154:GFO RS10995
gene id: 411154:GFO_RS10995
uniprot id: A0M3V3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

411154:GFO RS13380
gene id: 411154:GFO_RS13380
uniprot id: A0M597
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

411154:GFO RS14695
gene id: 411154:GFO_RS14695
uniprot id: A0M622
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

411154:GFO RS13365
gene id: 411154:GFO_RS13365
uniprot id: A0M594
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

411154:GFO RS13300
gene id: 411154:GFO_RS13300
uniprot id: A0M581
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

411154:GFO RS12825
gene id: 411154:GFO_RS12825
uniprot id: A0M4Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

411154:GFO RS08610
gene id: 411154:GFO_RS08610
uniprot id: A0M2F8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

411154:GFO RS05065
gene id: 411154:GFO_RS05065
uniprot id: A0M0A7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

411154:GFO RS15915
gene id: 411154:GFO_RS15915
uniprot id: A0M6S0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS00925
gene id: 411154:GFO_RS00925
uniprot id: A0LXT4
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS08690
gene id: 411154:GFO_RS08690
uniprot id: A0M2H6
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS15725
gene id: 411154:GFO_RS15725
uniprot id: A0M6N0
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS07260
gene id: 411154:GFO_RS07260
uniprot id: A0M1M5
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS01010
gene id: 411154:GFO_RS01010
uniprot id: A0LXV2
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

411154:GFO RS10190
gene id: 411154:GFO_RS10190
uniprot id: A0M3D7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

411154:GFO RS08130
gene id: 411154:GFO_RS08130
uniprot id: A0M260
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS13540
gene id: 411154:GFO_RS13540
uniprot id: A0M5D0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

411154:GFO RS01415
gene id: 411154:GFO_RS01415
uniprot id: A0LY33
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

411154:GFO RS09930
gene id: 411154:GFO_RS09930
uniprot id: A0M381
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

411154:GFO RS04725
gene id: 411154:GFO_RS04725
uniprot id: A0M038
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

411154:GFO RS12440
gene id: 411154:GFO_RS12440
uniprot id: A0M4Q1
names: Similarity
messages: Belongs to the PspA/IM30 family.

411154:GFO RS06035
gene id: 411154:GFO_RS06035
uniprot id: A0M0X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

411154:GFO RS05405
gene id: 411154:GFO_RS05405
uniprot id: A0M0I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS01760
gene id: 411154:GFO_RS01760
uniprot id: A0LYA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

411154:GFO RS12915
gene id: 411154:GFO_RS12915
uniprot id: A0M500
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

411154:GFO RS07815
gene id: 411154:GFO_RS07815
uniprot id: A0M1Z1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

411154:GFO RS09925
gene id: 411154:GFO_RS09925
uniprot id: A0M380
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

411154:GFO RS13830
gene id: 411154:GFO_RS13830
uniprot id: A0M5I3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

411154:GFO RS05965
gene id: 411154:GFO_RS05965
uniprot id: A0M0V8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

411154:GFO RS03900
gene id: 411154:GFO_RS03900
uniprot id: A0LZK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

411154:GFO RS16915
gene id: 411154:GFO_RS16915
uniprot id: A0M7C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

411154:GFO RS08315
gene id: 411154:GFO_RS08315
uniprot id: A0M298
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

411154:GFO RS15260
gene id: 411154:GFO_RS15260
uniprot id: A0M6D6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

411154:GFO RS08095
gene id: 411154:GFO_RS08095
uniprot id: A0M252
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

411154:GFO RS00620
gene id: 411154:GFO_RS00620
uniprot id: A0LXL9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

411154:GFO RS02945
gene id: 411154:GFO_RS02945
uniprot id: A0LZ02
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

411154:GFO RS15185
gene id: 411154:GFO_RS15185
uniprot id: A0M6C1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

411154:GFO RS15730
gene id: 411154:GFO_RS15730
uniprot id: A0M6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

411154:GFO RS15945
gene id: 411154:GFO_RS15945
uniprot id: A0M6S6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS01140
gene id: 411154:GFO_RS01140
uniprot id: A0LXX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS13940
gene id: 411154:GFO_RS13940
uniprot id: A0M5K6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

411154:GFO RS07415
gene id: 411154:GFO_RS07415
uniprot id: A0M1Q8
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13170
gene id: 411154:GFO_RS13170
uniprot id: A0M554
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

411154:GFO RS06115
gene id: 411154:GFO_RS06115
uniprot id: A0M0Y9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS16015
gene id: 411154:GFO_RS16015
uniprot id: A0M6U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

411154:GFO RS07330
gene id: 411154:GFO_RS07330
uniprot id: A0M1P1
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS14300
gene id: 411154:GFO_RS14300
uniprot id: A0M5T2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

411154:GFO RS07770
gene id: 411154:GFO_RS07770
uniprot id: A0M1Y2
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS11865
gene id: 411154:GFO_RS11865
uniprot id: A0M4C8
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

411154:GFO RS15910
gene id: 411154:GFO_RS15910
uniprot id: A0M6R9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

411154:GFO RS15770
gene id: 411154:GFO_RS15770
uniprot id: A0M6N9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

411154:GFO RS06320
gene id: 411154:GFO_RS06320
uniprot id: A0M135
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

411154:GFO RS02470
gene id: 411154:GFO_RS02470
uniprot id: A0LYQ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS12985
gene id: 411154:GFO_RS12985
uniprot id: A0M515
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS10555
gene id: 411154:GFO_RS10555
uniprot id: A0M3L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

411154:GFO RS09825
gene id: 411154:GFO_RS09825
uniprot id: A0M360
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

411154:GFO RS12415
gene id: 411154:GFO_RS12415
uniprot id: A0M4P5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

411154:GFO RS08245
gene id: 411154:GFO_RS08245
uniprot id: A0M284
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

411154:GFO RS13130
gene id: 411154:GFO_RS13130
uniprot id: A0M544
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

411154:GFO RS03685
gene id: 411154:GFO_RS03685
uniprot id: A0LZF8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

411154:GFO RS10660
gene id: 411154:GFO_RS10660
uniprot id: A0M3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

411154:GFO RS01335
gene id: 411154:GFO_RS01335
uniprot id: A0LY17
names: Similarity
messages: Belongs to the fabD family.

411154:GFO RS14315
gene id: 411154:GFO_RS14315
uniprot id: A0M5T6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

411154:GFO RS01435
gene id: 411154:GFO_RS01435
uniprot id: A0LY37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

411154:GFO RS09615
gene id: 411154:GFO_RS09615
uniprot id: A0M317
names: Similarity
messages: Belongs to the Dps family.

411154:GFO RS03105
gene id: 411154:GFO_RS03105
uniprot id: A0LZ35
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

411154:GFO RS15235
gene id: 411154:GFO_RS15235
uniprot id: A0M6D1
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS05040
gene id: 411154:GFO_RS05040
uniprot id: A0M0A2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

411154:GFO RS08430
gene id: 411154:GFO_RS08430
uniprot id: A0M2C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

411154:GFO RS09660
gene id: 411154:GFO_RS09660
uniprot id: A0M326
names: Similarity
messages: Belongs to the phosphohexose mutase family.

411154:GFO RS11680
gene id: 411154:GFO_RS11680
uniprot id: A0M491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

411154:GFO RS05305
gene id: 411154:GFO_RS05305
uniprot id: A0M0F6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

411154:GFO RS08970
gene id: 411154:GFO_RS08970
uniprot id: A0M2N0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

411154:GFO RS00920
gene id: 411154:GFO_RS00920
uniprot id: A0LXT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

411154:GFO RS15655
gene id: 411154:GFO_RS15655
uniprot id: A0M6L6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

411154:GFO RS00985
gene id: 411154:GFO_RS00985
uniprot id: A0LXU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

411154:GFO RS08370
gene id: 411154:GFO_RS08370
uniprot id: A0M2A9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS14960
gene id: 411154:GFO_RS14960
uniprot id: A0M676
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

411154:GFO RS09220
gene id: 411154:GFO_RS09220
uniprot id: A0M2T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

411154:GFO RS10255
gene id: 411154:GFO_RS10255
uniprot id: A0M3F0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

411154:GFO RS00490
gene id: 411154:GFO_RS00490
uniprot id: A0LXJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

411154:GFO RS15850
gene id: 411154:GFO_RS15850
uniprot id: A0M6Q5
names: Similarity
messages: Belongs to the RecJ family.

411154:GFO RS01100
gene id: 411154:GFO_RS01100
uniprot id: A0LXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

411154:GFO RS13370
gene id: 411154:GFO_RS13370
uniprot id: A0M595
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

411154:GFO RS05235
gene id: 411154:GFO_RS05235
uniprot id: A0M0E1
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13965
gene id: 411154:GFO_RS13965
uniprot id: A0M5L1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

411154:GFO RS05550
gene id: 411154:GFO_RS05550
uniprot id: A0M0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

411154:GFO RS12680
gene id: 411154:GFO_RS12680
uniprot id: A0M4V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

411154:GFO RS03000
gene id: 411154:GFO_RS03000
uniprot id: A0LZ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

411154:GFO RS05115
gene id: 411154:GFO_RS05115
uniprot id: A0M0B7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS13825
gene id: 411154:GFO_RS13825
uniprot id: A0M5I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

411154:GFO RS16870
gene id: 411154:GFO_RS16870
uniprot id: A0M7C0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

411154:GFO RS03990
gene id: 411154:GFO_RS03990
uniprot id: A0LZL9
names: Similarity
messages: Belongs to the peptidase S33 family.

411154:GFO RS14925
gene id: 411154:GFO_RS14925
uniprot id: A0M669
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

411154:GFO RS10840
gene id: 411154:GFO_RS10840
uniprot id: A0M3S2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

411154:GFO RS02865
gene id: 411154:GFO_RS02865
uniprot id: A0LYZ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

411154:GFO RS13325
gene id: 411154:GFO_RS13325
uniprot id: A0M586
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

411154:GFO RS13355
gene id: 411154:GFO_RS13355
uniprot id: A0M592
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

411154:GFO RS14000
gene id: 411154:GFO_RS14000
uniprot id: A0M5L8
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

411154:GFO RS02940
gene id: 411154:GFO_RS02940
uniprot id: A0LZ01
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

411154:GFO RS00815
gene id: 411154:GFO_RS00815
uniprot id: A0LXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

411154:GFO RS17220
gene id: 411154:GFO_RS17220
uniprot id: A0LZY1
names: Similarity
messages: Belongs to the barstar family.

411154:GFO RS05365
gene id: 411154:GFO_RS05365
uniprot id: A0M0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

411154:GFO RS02810
gene id: 411154:GFO_RS02810
uniprot id: A0LYX9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

411154:GFO RS00645
gene id: 411154:GFO_RS00645
uniprot id: A0LXM5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

411154:GFO RS07975
gene id: 411154:GFO_RS07975
uniprot id: A0M224
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

411154:GFO RS14825
gene id: 411154:GFO_RS14825
uniprot id: A0M649
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

411154:GFO RS12520
gene id: 411154:GFO_RS12520
uniprot id: A0M4S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

411154:GFO RS14305
gene id: 411154:GFO_RS14305
uniprot id: A0M5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

411154:GFO RS13310
gene id: 411154:GFO_RS13310
uniprot id: A0M583
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

411154:GFO RS01020
gene id: 411154:GFO_RS01020
uniprot id: A0LXV4
names: Similarity
messages: Belongs to the Skp family.

411154:GFO RS13095
gene id: 411154:GFO_RS13095
uniprot id: A0M537
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

411154:GFO RS06600
gene id: 411154:GFO_RS06600
uniprot id: A0M193
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

411154:GFO RS08115
gene id: 411154:GFO_RS08115
uniprot id: A0M257
names: Similarity
messages: Belongs to the SusD family.

411154:GFO RS04775
gene id: 411154:GFO_RS04775
uniprot id: A0M048
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS09210
gene id: 411154:GFO_RS09210
uniprot id: A0M2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

411154:GFO RS07095
gene id: 411154:GFO_RS07095
uniprot id: A0M1J1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

411154:GFO RS14010
gene id: 411154:GFO_RS14010
uniprot id: A0M5M0
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS16825
gene id: 411154:GFO_RS16825
uniprot id: A0M7A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

411154:GFO RS04570
gene id: 411154:GFO_RS04570
uniprot id: A0M006
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

411154:GFO RS16875
gene id: 411154:GFO_RS16875
uniprot id: A0M7C1
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS03005
gene id: 411154:GFO_RS03005
uniprot id: A0LZ14
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

411154:GFO RS12900
gene id: 411154:GFO_RS12900
uniprot id: A0M4Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS05310
gene id: 411154:GFO_RS05310
uniprot id: A0M0F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

411154:GFO RS03660
gene id: 411154:GFO_RS03660
uniprot id: A0LZF2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

411154:GFO RS01300
gene id: 411154:GFO_RS01300
uniprot id: A0LY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

411154:GFO RS17005
gene id: 411154:GFO_RS17005
uniprot id: A0M7E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS11845
gene id: 411154:GFO_RS11845
uniprot id: A0M4C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

411154:GFO RS09185
gene id: 411154:GFO_RS09185
uniprot id: A0M2S5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

411154:GFO RS12005
gene id: 411154:GFO_RS12005
uniprot id: A0M4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

411154:GFO RS06040
gene id: 411154:GFO_RS06040
uniprot id: A0M0X4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

411154:GFO RS13330
gene id: 411154:GFO_RS13330
uniprot id: A0M587
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

411154:GFO RS14580
gene id: 411154:GFO_RS14580
uniprot id: A0M5Z6
names: Similarity
messages: Belongs to the peptidase M13 family.

411154:GFO RS11260
gene id: 411154:GFO_RS11260
uniprot id: A0M403
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

411154:GFO RS11970
gene id: 411154:GFO_RS11970
uniprot id: A0M4F1
names: Similarity
messages: Belongs to the MEMO1 family.

411154:GFO RS15705
gene id: 411154:GFO_RS15705
uniprot id: A0M6M6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

411154:GFO RS07280
gene id: 411154:GFO_RS07280
uniprot id: A0M1N0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

411154:GFO RS06080
gene id: 411154:GFO_RS06080
uniprot id: A0M0Y2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

411154:GFO RS01540
gene id: 411154:GFO_RS01540
uniprot id: A0LY60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

411154:GFO RS03610
gene id: 411154:GFO_RS03610
uniprot id: A0LZE3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

411154:GFO RS15020
gene id: 411154:GFO_RS15020
uniprot id: A0M688
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

411154:GFO RS16975
gene id: 411154:GFO_RS16975
uniprot id: A0M7E1
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS10640
gene id: 411154:GFO_RS10640
uniprot id: A0M3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

411154:GFO RS13980
gene id: 411154:GFO_RS13980
uniprot id: A0M5L4
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS15950
gene id: 411154:GFO_RS15950
uniprot id: A0M6S7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

411154:GFO RS01345
gene id: 411154:GFO_RS01345
uniprot id: A0LY19
names: Similarity
messages: Belongs to the fructosamine kinase family.

411154:GFO RS00915
gene id: 411154:GFO_RS00915
uniprot id: A0LXT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

411154:GFO RS09880
gene id: 411154:GFO_RS09880
uniprot id: A0M371
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

411154:GFO RS08100
gene id: 411154:GFO_RS08100
uniprot id: A0M253
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

411154:GFO RS07050
gene id: 411154:GFO_RS07050
uniprot id: A0M1I2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

411154:GFO RS10220
gene id: 411154:GFO_RS10220
uniprot id: A0M3E3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

411154:GFO RS16805
gene id: 411154:GFO_RS16805
uniprot id: A0M7A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS15305
gene id: 411154:GFO_RS15305
uniprot id: A0M6E6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

411154:GFO RS13195
gene id: 411154:GFO_RS13195
uniprot id: A0M560
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

411154:GFO RS00820
gene id: 411154:GFO_RS00820
uniprot id: A0LXR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

411154:GFO RS15815
gene id: 411154:GFO_RS15815
uniprot id: A0M6P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

411154:GFO RS09385
gene id: 411154:GFO_RS09385
uniprot id: A0M2W8
names: Similarity
messages: Belongs to the asparagine synthetase family.

411154:GFO RS02260
gene id: 411154:GFO_RS02260
uniprot id: A0LYL5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

411154:GFO RS00955
gene id: 411154:GFO_RS00955
uniprot id: A0LXU0
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13520
gene id: 411154:GFO_RS13520
uniprot id: A0M5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

411154:GFO RS08695
gene id: 411154:GFO_RS08695
uniprot id: A0M2H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

411154:GFO RS04970
gene id: 411154:GFO_RS04970
uniprot id: A0M088
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS00845
gene id: 411154:GFO_RS00845
uniprot id: A0LXR6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

411154:GFO RS05525
gene id: 411154:GFO_RS05525
uniprot id: A0M0L0
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

411154:GFO RS03880
gene id: 411154:GFO_RS03880
uniprot id: A0LZJ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

411154:GFO RS05650
gene id: 411154:GFO_RS05650
uniprot id: A0M0N7
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS03010
gene id: 411154:GFO_RS03010
uniprot id: A0LZ15
names: Similarity
messages: Belongs to the IMPACT family.

411154:GFO RS08530
gene id: 411154:GFO_RS08530
uniprot id: A0M2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

411154:GFO RS01150
gene id: 411154:GFO_RS01150
uniprot id: A0LXY1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

411154:GFO RS12095
gene id: 411154:GFO_RS12095
uniprot id: A0M4H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

411154:GFO RS13390
gene id: 411154:GFO_RS13390
uniprot id: A0M599
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

411154:GFO RS05205
gene id: 411154:GFO_RS05205
uniprot id: A0M0D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

411154:GFO RS03530
gene id: 411154:GFO_RS03530
uniprot id: A0LZC7
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

411154:GFO RS09895
gene id: 411154:GFO_RS09895
uniprot id: A0M374
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

411154:GFO RS15290
gene id: 411154:GFO_RS15290
uniprot id: A0M6E3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

411154:GFO RS13535
gene id: 411154:GFO_RS13535
uniprot id: A0M5C9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

411154:GFO RS16020
gene id: 411154:GFO_RS16020
uniprot id: A0M6U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

411154:GFO RS16375
gene id: 411154:GFO_RS16375
uniprot id: A0M713
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

411154:GFO RS13225
gene id: 411154:GFO_RS13225
uniprot id: A0M566
names: Similarity
messages: Belongs to the citrate synthase family.

411154:GFO RS10780
gene id: 411154:GFO_RS10780
uniprot id: A0M3R0
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS02410
gene id: 411154:GFO_RS02410
uniprot id: A0LYP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

411154:GFO RS16075
gene id: 411154:GFO_RS16075
uniprot id: A0M6V3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

411154:GFO RS14515
gene id: 411154:GFO_RS14515
uniprot id: A0M5Y3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

411154:GFO RS13285
gene id: 411154:GFO_RS13285
uniprot id: A0M578
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

411154:GFO RS01755
gene id: 411154:GFO_RS01755
uniprot id: A0LYA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

411154:GFO RS01695
gene id: 411154:GFO_RS01695
uniprot id: A0LY95
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

411154:GFO RS05155
gene id: 411154:GFO_RS05155
uniprot id: A0M0C5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

411154:GFO RS12635
gene id: 411154:GFO_RS12635
uniprot id: A0M4U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

411154:GFO RS09620
gene id: 411154:GFO_RS09620
uniprot id: A0M318
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

411154:GFO RS04745
gene id: 411154:GFO_RS04745
uniprot id: A0M042
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

411154:GFO RS07940
gene id: 411154:GFO_RS07940
uniprot id: A0M218
names: Cofactor
messages: Binds 1 zinc ion per subunit.

411154:GFO RS03110
gene id: 411154:GFO_RS03110
uniprot id: A0LZ36
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

411154:GFO RS09945
gene id: 411154:GFO_RS09945
uniprot id: A0M386
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

411154:GFO RS07895
gene id: 411154:GFO_RS07895
uniprot id: A0M207
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

411154:GFO RS11895
gene id: 411154:GFO_RS11895
uniprot id: A0M4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

411154:GFO RS14230
gene id: 411154:GFO_RS14230
uniprot id: A0M5R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

411154:GFO RS16025
gene id: 411154:GFO_RS16025
uniprot id: A0M6U2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

411154:GFO RS00640
gene id: 411154:GFO_RS00640
uniprot id: A0LXM3
names: Similarity
messages: Belongs to the AHA1 family.

411154:GFO RS15925
gene id: 411154:GFO_RS15925
uniprot id: A0M6S2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

411154:GFO RS16525
gene id: 411154:GFO_RS16525
uniprot id: A0M746
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

411154:GFO RS08260
gene id: 411154:GFO_RS08260
uniprot id: A0M287
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

411154:GFO RS04530
gene id: 411154:GFO_RS04530
uniprot id: A0LZZ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

411154:GFO RS08765
gene id: 411154:GFO_RS08765
uniprot id: A0M2J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

411154:GFO RS14340
gene id: 411154:GFO_RS14340
uniprot id: A0M5U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

411154:GFO RS07885
gene id: 411154:GFO_RS07885
uniprot id: A0M205
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

411154:GFO RS09025
gene id: 411154:GFO_RS09025
uniprot id: A0M2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

411154:GFO RS00115
gene id: 411154:GFO_RS00115
uniprot id: A0LXC1
names: Subcellular Location Annotation
messages: Membrane

411154:GFO RS13850
gene id: 411154:GFO_RS13850
uniprot id: A0M5I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

411154:GFO RS02195
gene id: 411154:GFO_RS02195
uniprot id: A0LYK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

411154:GFO RS14740
gene id: 411154:GFO_RS14740
uniprot id: A0M631
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

411154:GFO RS15675
gene id: 411154:GFO_RS15675
uniprot id: A0M6M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

411154:GFO RS10180
gene id: 411154:GFO_RS10180
uniprot id: A0M3D5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

411154:GFO RS09000
gene id: 411154:GFO_RS09000
uniprot id: A0M2N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

411154:GFO RS13650
gene id: 411154:GFO_RS13650
uniprot id: A0M5F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

411154:GFO RS15325
gene id: 411154:GFO_RS15325
uniprot id: A0M6F0
names: Similarity
messages: Belongs to the DprA/Smf family.

411154:GFO RS02815
gene id: 411154:GFO_RS02815
uniprot id: A0LYY0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

411154:GFO RS12995
gene id: 411154:GFO_RS12995
uniprot id: A0M517
names: Similarity
messages: Belongs to the peptidase S66 family.

411154:GFO RS05625
gene id: 411154:GFO_RS05625
uniprot id: A0M0N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

411154:GFO RS01655
gene id: 411154:GFO_RS01655
uniprot id: A0LY87
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.