408015:SXIM RS25760
gene id: 408015:SXIM_RS25760
uniprot id: A0A0F7G1E2
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS26780
gene id: 408015:SXIM_RS26780
uniprot id: A0A0F7G0S6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

408015:SXIM RS13495
gene id: 408015:SXIM_RS13495
uniprot id: A0A0F7FUP9
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

408015:SXIM RS19175
gene id: 408015:SXIM_RS19175
uniprot id: A0A0F7FX64
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

408015:SXIM RS07160
gene id: 408015:SXIM_RS07160
uniprot id: A0A0F7FRV2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

408015:SXIM RS07155
gene id: 408015:SXIM_RS07155
uniprot id: A0A0F7CNF8
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS00415
gene id: 408015:SXIM_RS00415
uniprot id: A0A0F7FNS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

408015:SXIM RS17585
gene id: 408015:SXIM_RS17585
uniprot id: A0A0F7FWJ6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

408015:SXIM RS09590
gene id: 408015:SXIM_RS09590
uniprot id: A0A0F7FSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

408015:SXIM RS20430
gene id: 408015:SXIM_RS20430
uniprot id: A0A0F7FZ51
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

408015:SXIM RS18305
gene id: 408015:SXIM_RS18305
uniprot id: A0A0F7FWX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS23855
gene id: 408015:SXIM_RS23855
uniprot id: A0A0F7G151
names: Similarity
messages: Belongs to the peptidase S66 family.

408015:SXIM RS01645
gene id: 408015:SXIM_RS01645
uniprot id: A0A0F7FQN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

408015:SXIM RS01610
gene id: 408015:SXIM_RS01610
uniprot id: A0A0F7FPI8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

408015:SXIM RS01485
gene id: 408015:SXIM_RS01485
uniprot id: A0A0F7FQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

408015:SXIM RS02240
gene id: 408015:SXIM_RS02240
uniprot id: A0A0F7FPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS26760
gene id: 408015:SXIM_RS26760
uniprot id: A0A0F7G0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS07665
gene id: 408015:SXIM_RS07665
uniprot id: A0A0F7FS54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

408015:SXIM RS05045
gene id: 408015:SXIM_RS05045
uniprot id: A0A0F7FQY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

408015:SXIM RS02385
gene id: 408015:SXIM_RS02385
uniprot id: A0A0F7FPC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

408015:SXIM RS04295
gene id: 408015:SXIM_RS04295
uniprot id: A0A0F7CN42
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

408015:SXIM RS03805
gene id: 408015:SXIM_RS03805
uniprot id: A0A0F7FRM3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

408015:SXIM RS18240
gene id: 408015:SXIM_RS18240
uniprot id: A0A0F7CPQ3
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS23165
gene id: 408015:SXIM_RS23165
uniprot id: A0A0F7G0W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

408015:SXIM RS15650
gene id: 408015:SXIM_RS15650
uniprot id: A0A0F7FWX3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

408015:SXIM RS04260
gene id: 408015:SXIM_RS04260
uniprot id: A0A0F7FQK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

408015:SXIM RS22255
gene id: 408015:SXIM_RS22255
uniprot id: A0A0F7CQ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

408015:SXIM RS21790
gene id: 408015:SXIM_RS21790
uniprot id: A0A0F7FYG1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

408015:SXIM RS17270
gene id: 408015:SXIM_RS17270
uniprot id: A0A0F7FW88
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10125
gene id: 408015:SXIM_RS10125
uniprot id: A0A0F7FT91
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

408015:SXIM RS21250
gene id: 408015:SXIM_RS21250
uniprot id: A0A0F7FYP5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

408015:SXIM RS22480
gene id: 408015:SXIM_RS22480
uniprot id: A0A0F7G0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS19200
gene id: 408015:SXIM_RS19200
uniprot id: A0A0F7FYU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

408015:SXIM RS15605
gene id: 408015:SXIM_RS15605
uniprot id: A0A0F7CPE7
names: Similarity
messages: Belongs to the peptidase C40 family.

408015:SXIM RS21835
gene id: 408015:SXIM_RS21835
uniprot id: A0A0F7CQ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

408015:SXIM RS09735
gene id: 408015:SXIM_RS09735
uniprot id: A0A0F7FSQ0
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS24310
gene id: 408015:SXIM_RS24310
uniprot id: A0A0F7G1C2
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS15725
gene id: 408015:SXIM_RS15725
uniprot id: A0A0F7FVR4
names: Subcellular Location Annotation
messages: Cytoplasm

408015:SXIM RS10765
gene id: 408015:SXIM_RS10765
uniprot id: A0A0F7FTI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS25395
gene id: 408015:SXIM_RS25395
uniprot id: A0A0F7CQJ4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS17850
gene id: 408015:SXIM_RS17850
uniprot id: A0A0F7FY57
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

408015:SXIM RS14815
gene id: 408015:SXIM_RS14815
uniprot id: A0A0F7CPB4
names: Similarity
messages: Belongs to the histone deacetylase family.

408015:SXIM RS06920
gene id: 408015:SXIM_RS06920
uniprot id: A0A0F7FRS2
names: Similarity
messages: Belongs to the FGGY kinase family.

408015:SXIM RS10965
gene id: 408015:SXIM_RS10965
uniprot id: A0A0F7FUT9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS14235
gene id: 408015:SXIM_RS14235
uniprot id: A0A0F7FVH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS11515
gene id: 408015:SXIM_RS11515
uniprot id: A0A0F7FTJ6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

408015:SXIM RS26065
gene id: 408015:SXIM_RS26065
uniprot id: A0A0F7G0V3
names: Similarity
messages: Belongs to the thioesterase family.

408015:SXIM RS07815
gene id: 408015:SXIM_RS07815
uniprot id: A0A0F7FSE8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

408015:SXIM RS02425
gene id: 408015:SXIM_RS02425
uniprot id: A0A0F7FPU1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS02835
gene id: 408015:SXIM_RS02835
uniprot id: A0A0F7FPX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS20710
gene id: 408015:SXIM_RS20710
uniprot id: A0A0F7FXY8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

408015:SXIM RS16900
gene id: 408015:SXIM_RS16900
uniprot id: A0A0F7FW70
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

408015:SXIM RS26440
gene id: 408015:SXIM_RS26440
uniprot id: A0A0F7G2C2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

408015:SXIM RS03130
gene id: 408015:SXIM_RS03130
uniprot id: A0A0F7FRC2
names: Similarity
messages: Belongs to the cytochrome P450 family.

408015:SXIM RS01820
gene id: 408015:SXIM_RS01820
uniprot id: A0A0F7FPL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

408015:SXIM RS20660
gene id: 408015:SXIM_RS20660
uniprot id: A0A0F7FZJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

408015:SXIM RS24930
gene id: 408015:SXIM_RS24930
uniprot id: A0A0F7CQH5
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS08925
gene id: 408015:SXIM_RS08925
uniprot id: A0A0F7CNN0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

408015:SXIM RS13980
gene id: 408015:SXIM_RS13980
uniprot id: A0A0F7FVD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

408015:SXIM RS01550
gene id: 408015:SXIM_RS01550
uniprot id: A0A0F7FQF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

408015:SXIM RS10280
gene id: 408015:SXIM_RS10280
uniprot id: A0A0F7FTS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

408015:SXIM RS03710
gene id: 408015:SXIM_RS03710
uniprot id: A0A0F7FRK7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

408015:SXIM RS21895
gene id: 408015:SXIM_RS21895
uniprot id: A0A0F7G080
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

408015:SXIM RS08965
gene id: 408015:SXIM_RS08965
uniprot id: A0A0F7FSU0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

408015:SXIM RS04455
gene id: 408015:SXIM_RS04455
uniprot id: A0A0F7FS06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

408015:SXIM RS05615
gene id: 408015:SXIM_RS05615
uniprot id: A0A0F7FQV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS15280
gene id: 408015:SXIM_RS15280
uniprot id: A0A0F7CPD3
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS07560
gene id: 408015:SXIM_RS07560
uniprot id: A0A0F7FRP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

408015:SXIM RS07395
gene id: 408015:SXIM_RS07395
uniprot id: A0A0F7CNG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

408015:SXIM RS26645
gene id: 408015:SXIM_RS26645
uniprot id: A0A0F7G1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS07365
gene id: 408015:SXIM_RS07365
uniprot id: A0A0F7FRY4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

408015:SXIM RS09085
gene id: 408015:SXIM_RS09085
uniprot id: A0A0F7FT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS05405
gene id: 408015:SXIM_RS05405
uniprot id: A0A0F7FR88
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

408015:SXIM RS22335
gene id: 408015:SXIM_RS22335
uniprot id: A0A0F7FYQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

408015:SXIM RS24905
gene id: 408015:SXIM_RS24905
uniprot id: A0A0F7CQH4
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

408015:SXIM RS25020
gene id: 408015:SXIM_RS25020
uniprot id: A0A0F7FZY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

408015:SXIM RS22810
gene id: 408015:SXIM_RS22810
uniprot id: A0A0F7CQ90
names: Cofactor
messages: Binds 1 zinc ion per subunit.

408015:SXIM RS15920
gene id: 408015:SXIM_RS15920
uniprot id: A0A0F7FVU7
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

408015:SXIM RS21755
gene id: 408015:SXIM_RS21755
uniprot id: A0A0F7FYF8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

408015:SXIM RS23360
gene id: 408015:SXIM_RS23360
uniprot id: A0A0F7FZ69
names: Similarity
messages: Belongs to the cytochrome P450 family.

408015:SXIM RS03315
gene id: 408015:SXIM_RS03315
uniprot id: A0A0F7FPT2
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

408015:SXIM RS12040
gene id: 408015:SXIM_RS12040
uniprot id: A0A0F7FTV7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

408015:SXIM RS21610
gene id: 408015:SXIM_RS21610
uniprot id: A0A0F7G035
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

408015:SXIM RS23310
gene id: 408015:SXIM_RS23310
uniprot id: A0A0F7FZK4
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

408015:SXIM RS03670
gene id: 408015:SXIM_RS03670
uniprot id: A0A0F7FQA8
names: Similarity
messages: Belongs to the peptidase S1 family.

408015:SXIM RS07230
gene id: 408015:SXIM_RS07230
uniprot id: A0A0F7CNG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

408015:SXIM RS16520
gene id: 408015:SXIM_RS16520
uniprot id: A0A0F7FXA1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

408015:SXIM RS15130
gene id: 408015:SXIM_RS15130
uniprot id: A0A0F7FVZ8
names: Similarity
messages: Belongs to the TPP enzyme family.

408015:SXIM RS09155
gene id: 408015:SXIM_RS09155
uniprot id: A0A0F7FT81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

408015:SXIM RS25125
gene id: 408015:SXIM_RS25125
uniprot id: A0A0F7G0F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

408015:SXIM RS06245
gene id: 408015:SXIM_RS06245
uniprot id: A0A0F7FRS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS10660
gene id: 408015:SXIM_RS10660
uniprot id: A0A0F7FUN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS04270
gene id: 408015:SXIM_RS04270
uniprot id: A0A0F7CN41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

408015:SXIM RS02670
gene id: 408015:SXIM_RS02670
uniprot id: A0A0F7CMX5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS27020
gene id: 408015:SXIM_RS27020
uniprot id: A0A0F7G0R0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

408015:SXIM RS09455
gene id: 408015:SXIM_RS09455
uniprot id: A0A0F7FTC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

408015:SXIM RS07775
gene id: 408015:SXIM_RS07775
uniprot id: A0A0F7FRT1
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

408015:SXIM RS03655
gene id: 408015:SXIM_RS03655
uniprot id: A0A0F7FPY8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS07600
gene id: 408015:SXIM_RS07600
uniprot id: A0A0F7FTA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

408015:SXIM RS21035
gene id: 408015:SXIM_RS21035
uniprot id: A0A0F7FZG1
names: Subcellular Location Annotation
messages: Cytoplasm

408015:SXIM RS14865
gene id: 408015:SXIM_RS14865
uniprot id: A0A0F7FWR1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

408015:SXIM RS04210
gene id: 408015:SXIM_RS04210
uniprot id: A0A0F7FRW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

408015:SXIM RS03770
gene id: 408015:SXIM_RS03770
uniprot id: A0A0F7FRL7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS03400
gene id: 408015:SXIM_RS03400
uniprot id: A0A0F7FPU6
names: Similarity
messages: Belongs to the oxoprolinase family.

408015:SXIM RS17225
gene id: 408015:SXIM_RS17225
uniprot id: A0A0F7FWS8
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

408015:SXIM RS03725
gene id: 408015:SXIM_RS03725
uniprot id: A0A0F7CN19
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

408015:SXIM RS21255
gene id: 408015:SXIM_RS21255
uniprot id: A0A0F7FY95
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

408015:SXIM RS12930
gene id: 408015:SXIM_RS12930
uniprot id: A0A0F7FU70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

408015:SXIM RS12815
gene id: 408015:SXIM_RS12815
uniprot id: A0A0F7CP35
names: Similarity
messages: Belongs to the peptidase S1C family.

408015:SXIM RS16505
gene id: 408015:SXIM_RS16505
uniprot id: A0A0F7FW32
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

408015:SXIM RS11115
gene id: 408015:SXIM_RS11115
uniprot id: A0A0F7FUW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

408015:SXIM RS00330
gene id: 408015:SXIM_RS00330
uniprot id: A0A0F7CMN1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

408015:SXIM RS15985
gene id: 408015:SXIM_RS15985
uniprot id: A0A0F7CPG2
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10255
gene id: 408015:SXIM_RS10255
uniprot id: A0A0F7FTB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

408015:SXIM RS07695
gene id: 408015:SXIM_RS07695
uniprot id: A0A0F7FS58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

408015:SXIM RS06995
gene id: 408015:SXIM_RS06995
uniprot id: A0A0F7FT02
names: Similarity
messages: Belongs to the CutA family.

408015:SXIM RS26910
gene id: 408015:SXIM_RS26910
uniprot id: A0A0F7CQQ5
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS11135
gene id: 408015:SXIM_RS11135
uniprot id: A0A0F7FUY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS28165
gene id: 408015:SXIM_RS28165
uniprot id: A0A0F7FVU6
names: Similarity
messages: Belongs to the peptidase S11 family.

408015:SXIM RS13130
gene id: 408015:SXIM_RS13130
uniprot id: A0A0F7CP48
names: Similarity
messages: Belongs to the thioredoxin family.

408015:SXIM RS18970
gene id: 408015:SXIM_RS18970
uniprot id: A0A0F7FXN0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

408015:SXIM RS25260
gene id: 408015:SXIM_RS25260
uniprot id: A0A0F7G022
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS23705
gene id: 408015:SXIM_RS23705
uniprot id: A0A0F7G0K4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

408015:SXIM RS14160
gene id: 408015:SXIM_RS14160
uniprot id: A0A0F7FUQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

408015:SXIM RS01670
gene id: 408015:SXIM_RS01670
uniprot id: A0A0F7FPC0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

408015:SXIM RS20495
gene id: 408015:SXIM_RS20495
uniprot id: A0A0F7FZ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

408015:SXIM RS20435
gene id: 408015:SXIM_RS20435
uniprot id: A0A0F7FY83
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

408015:SXIM RS00025
gene id: 408015:SXIM_RS00025
uniprot id: A0A0R8K4J4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS03845
gene id: 408015:SXIM_RS03845
uniprot id: A0A0F7FRL0
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

408015:SXIM RS07090
gene id: 408015:SXIM_RS07090
uniprot id: A0A0F7FS40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS16465
gene id: 408015:SXIM_RS16465
uniprot id: A0A0F7FX93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

408015:SXIM RS04865
gene id: 408015:SXIM_RS04865
uniprot id: A0A0F7FR16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

408015:SXIM RS12845
gene id: 408015:SXIM_RS12845
uniprot id: A0A0F7FVP5
names: Similarity
messages: Belongs to the peptidase M24B family.

408015:SXIM RS06850
gene id: 408015:SXIM_RS06850
uniprot id: A0A0F7FSY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

408015:SXIM RS21745
gene id: 408015:SXIM_RS21745
uniprot id: A0A0F7FZT0
names: Similarity
messages: Belongs to the acylphosphatase family.

408015:SXIM RS00725
gene id: 408015:SXIM_RS00725
uniprot id: A0A0F7FP61
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

408015:SXIM RS08545
gene id: 408015:SXIM_RS08545
uniprot id: A0A0F7FTS3
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

408015:SXIM RS12125
gene id: 408015:SXIM_RS12125
uniprot id: A0A0F7CP08
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS24290
gene id: 408015:SXIM_RS24290
uniprot id: A0A0F7CQE9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS07085
gene id: 408015:SXIM_RS07085
uniprot id: A0A0F7FT16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS04385
gene id: 408015:SXIM_RS04385
uniprot id: A0A0F7FQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

408015:SXIM RS22970
gene id: 408015:SXIM_RS22970
uniprot id: A0A0F7FYY9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS02975
gene id: 408015:SXIM_RS02975
uniprot id: A0A0F7FRA0
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS11420
gene id: 408015:SXIM_RS11420
uniprot id: A0A0F7CNY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

408015:SXIM RS06020
gene id: 408015:SXIM_RS06020
uniprot id: A0A0F7FSP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

408015:SXIM RS03885
gene id: 408015:SXIM_RS03885
uniprot id: A0A0F7FQ18
names: Similarity
messages: Belongs to the barstar family.

408015:SXIM RS19480
gene id: 408015:SXIM_RS19480
uniprot id: A0A0F7FXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS01935
gene id: 408015:SXIM_RS01935
uniprot id: A0A0F7CMU6
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

408015:SXIM RS22550
gene id: 408015:SXIM_RS22550
uniprot id: A0A0F7FZ91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

408015:SXIM RS05245
gene id: 408015:SXIM_RS05245
uniprot id: A0A0F7FQP1
names: Similarity
messages: Belongs to the arsA ATPase family.

408015:SXIM RS07615
gene id: 408015:SXIM_RS07615
uniprot id: A0A0F7FTB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

408015:SXIM RS15340
gene id: 408015:SXIM_RS15340
uniprot id: A0A0F7FWT1
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

408015:SXIM RS14975
gene id: 408015:SXIM_RS14975
uniprot id: A0A0F7CPC0
names: Similarity
messages: Belongs to the UbiD family.

408015:SXIM RS17100
gene id: 408015:SXIM_RS17100
uniprot id: A0A0F7FWA3
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

408015:SXIM RS25230
gene id: 408015:SXIM_RS25230
uniprot id: A0A0F7CQI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS04220
gene id: 408015:SXIM_RS04220
uniprot id: A0A0F7FRR9
names: Similarity
messages: Belongs to the IlvD/Edd family.

408015:SXIM RS16570
gene id: 408015:SXIM_RS16570
uniprot id: A0A0F7FVW9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10365
gene id: 408015:SXIM_RS10365
uniprot id: A0A0F7FUJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

408015:SXIM RS17130
gene id: 408015:SXIM_RS17130
uniprot id: A0A0F7CPK8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

408015:SXIM RS10835
gene id: 408015:SXIM_RS10835
uniprot id: A0A0F7FUT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS10235
gene id: 408015:SXIM_RS10235
uniprot id: A0A0F7FSW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

408015:SXIM RS22945
gene id: 408015:SXIM_RS22945
uniprot id: A0A0F7G0U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS14905
gene id: 408015:SXIM_RS14905
uniprot id: A0A0F7FV32
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS10770
gene id: 408015:SXIM_RS10770
uniprot id: A0A0F7FUS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

408015:SXIM RS13550
gene id: 408015:SXIM_RS13550
uniprot id: A0A0F7CP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

408015:SXIM RS03795
gene id: 408015:SXIM_RS03795
uniprot id: A0A0F7FQC5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

408015:SXIM RS02820
gene id: 408015:SXIM_RS02820
uniprot id: A0A0F7FPM6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

408015:SXIM RS13005
gene id: 408015:SXIM_RS13005
uniprot id: A0A0F7FV20
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04275
gene id: 408015:SXIM_RS04275
uniprot id: A0A0F7FQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS18135
gene id: 408015:SXIM_RS18135
uniprot id: A0A0F7FY30
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

408015:SXIM RS07345
gene id: 408015:SXIM_RS07345
uniprot id: A0A0F7CNG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

408015:SXIM RS01290
gene id: 408015:SXIM_RS01290
uniprot id: A0A0F7FQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS14605
gene id: 408015:SXIM_RS14605
uniprot id: A0A0F7FWG2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

408015:SXIM RS03205
gene id: 408015:SXIM_RS03205
uniprot id: A0A0F7FRB1
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

408015:SXIM RS21820
gene id: 408015:SXIM_RS21820
uniprot id: A0A0F7FYG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

408015:SXIM RS24340
gene id: 408015:SXIM_RS24340
uniprot id: A0A0F7CQF1
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS24835
gene id: 408015:SXIM_RS24835
uniprot id: A0A0F7CQH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS26495
gene id: 408015:SXIM_RS26495
uniprot id: A0A0F7G106
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

408015:SXIM RS10440
gene id: 408015:SXIM_RS10440
uniprot id: A0A0F7FTU3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

408015:SXIM RS12710
gene id: 408015:SXIM_RS12710
uniprot id: A0A0F7FVM6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

408015:SXIM RS08685
gene id: 408015:SXIM_RS08685
uniprot id: A0A0F7FTU1
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

408015:SXIM RS17605
gene id: 408015:SXIM_RS17605
uniprot id: A0A0F7FWF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS14490
gene id: 408015:SXIM_RS14490
uniprot id: A0A0F7CPA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

408015:SXIM RS07040
gene id: 408015:SXIM_RS07040
uniprot id: A0A0F7FRT8
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

408015:SXIM RS16770
gene id: 408015:SXIM_RS16770
uniprot id: A0A0F7FWN7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

408015:SXIM RS08605
gene id: 408015:SXIM_RS08605
uniprot id: A0A0F7CNL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

408015:SXIM RS07965
gene id: 408015:SXIM_RS07965
uniprot id: A0A0F7FS99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS06115
gene id: 408015:SXIM_RS06115
uniprot id: A0A0F7FSQ3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

408015:SXIM RS13225
gene id: 408015:SXIM_RS13225
uniprot id: A0A0F7CP52
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

408015:SXIM RS04595
gene id: 408015:SXIM_RS04595
uniprot id: A0A0F7CN54
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS02410
gene id: 408015:SXIM_RS02410
uniprot id: A0A0F7FPD0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

408015:SXIM RS13075
gene id: 408015:SXIM_RS13075
uniprot id: A0A0F7FVV5
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS26890
gene id: 408015:SXIM_RS26890
uniprot id: A0A0F7CQQ4
names: Similarity
messages: Belongs to the HypD family.

408015:SXIM RS11745
gene id: 408015:SXIM_RS11745
uniprot id: A0A0F7FTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS28035
gene id: 408015:SXIM_RS28035
uniprot id: A0A0F7FT54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

408015:SXIM RS15190
gene id: 408015:SXIM_RS15190
uniprot id: A0A0F7FW12
names: Similarity
messages: Belongs to the PstS family.

408015:SXIM RS09135
gene id: 408015:SXIM_RS09135
uniprot id: A0A0F7FU35
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

408015:SXIM RS24990
gene id: 408015:SXIM_RS24990
uniprot id: A0A0F7FZX9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

408015:SXIM RS25285
gene id: 408015:SXIM_RS25285
uniprot id: A0A0F7G0H7
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

408015:SXIM RS05260
gene id: 408015:SXIM_RS05260
uniprot id: A0A0F7FR03
names: Similarity
messages: Belongs to the peptidase C40 family.

408015:SXIM RS02325
gene id: 408015:SXIM_RS02325
uniprot id: A0A0F7FPB6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

408015:SXIM RS09790
gene id: 408015:SXIM_RS09790
uniprot id: A0A0F7FUD9
names: Similarity
messages: Belongs to the peptidase S33 family.

408015:SXIM RS19370
gene id: 408015:SXIM_RS19370
uniprot id: A0A0F7FXC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS25620
gene id: 408015:SXIM_RS25620
uniprot id: A0A0F7CQK3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

408015:SXIM RS10450
gene id: 408015:SXIM_RS10450
uniprot id: A0A0F7CNU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

408015:SXIM RS01575
gene id: 408015:SXIM_RS01575
uniprot id: A0A0F7FQG4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

408015:SXIM RS09280
gene id: 408015:SXIM_RS09280
uniprot id: A0A0F7FSX6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

408015:SXIM RS10900
gene id: 408015:SXIM_RS10900
uniprot id: A0A0F7CNW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

408015:SXIM RS01590
gene id: 408015:SXIM_RS01590
uniprot id: A0A0F7CMT2
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

408015:SXIM RS26500
gene id: 408015:SXIM_RS26500
uniprot id: A0A0F7CQN8
names: Similarity
messages: Belongs to the peptidase S51 family.

408015:SXIM RS21080
gene id: 408015:SXIM_RS21080
uniprot id: A0A0F7FY44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS03345
gene id: 408015:SXIM_RS03345
uniprot id: A0A0F7FPT7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

408015:SXIM RS21900
gene id: 408015:SXIM_RS21900
uniprot id: A0A0F7FYJ1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS12005
gene id: 408015:SXIM_RS12005
uniprot id: A0A0F7FVE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

408015:SXIM RS17290
gene id: 408015:SXIM_RS17290
uniprot id: A0A0F7FW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS21490
gene id: 408015:SXIM_RS21490
uniprot id: A0A0F7FYT8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

408015:SXIM RS11440
gene id: 408015:SXIM_RS11440
uniprot id: A0A0F7FV36
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

408015:SXIM RS12010
gene id: 408015:SXIM_RS12010
uniprot id: A0A0F7FTV4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04025
gene id: 408015:SXIM_RS04025
uniprot id: A0A0F7FRQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

408015:SXIM RS14125
gene id: 408015:SXIM_RS14125
uniprot id: A0A0F7FWB8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS15460
gene id: 408015:SXIM_RS15460
uniprot id: A0A0F7FWU8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

408015:SXIM RS03940
gene id: 408015:SXIM_RS03940
uniprot id: A0A0F7CN27
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS13275
gene id: 408015:SXIM_RS13275
uniprot id: A0A0F7FVV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

408015:SXIM RS07850
gene id: 408015:SXIM_RS07850
uniprot id: A0A0F7CNI7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

408015:SXIM RS06615
gene id: 408015:SXIM_RS06615
uniprot id: A0A0F7CND6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

408015:SXIM RS08785
gene id: 408015:SXIM_RS08785
uniprot id: A0A0F7FS83
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS11150
gene id: 408015:SXIM_RS11150
uniprot id: A0A0F7CNW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS18520
gene id: 408015:SXIM_RS18520
uniprot id: A0A0F7FX03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

408015:SXIM RS22770
gene id: 408015:SXIM_RS22770
uniprot id: A0A0F7FYV4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

408015:SXIM RS04405
gene id: 408015:SXIM_RS04405
uniprot id: A0A0F7FRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

408015:SXIM RS00685
gene id: 408015:SXIM_RS00685
uniprot id: A0A0F7FNK9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

408015:SXIM RS20050
gene id: 408015:SXIM_RS20050
uniprot id: A0A0F7CPX7
names: Similarity
messages: Belongs to the peptidase C40 family.

408015:SXIM RS22375
gene id: 408015:SXIM_RS22375
uniprot id: A0A0F7G010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS08770
gene id: 408015:SXIM_RS08770
uniprot id: A0A0F7FSS9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS11600
gene id: 408015:SXIM_RS11600
uniprot id: A0A0F7CNY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

408015:SXIM RS15915
gene id: 408015:SXIM_RS15915
uniprot id: A0A0F7FWD4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

408015:SXIM RS05180
gene id: 408015:SXIM_RS05180
uniprot id: A0A0F7FQN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

408015:SXIM RS06845
gene id: 408015:SXIM_RS06845
uniprot id: A0A0F7CNE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

408015:SXIM RS17395
gene id: 408015:SXIM_RS17395
uniprot id: A0A0F7FXP8
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS03970
gene id: 408015:SXIM_RS03970
uniprot id: A0A0F7FRP7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

408015:SXIM RS10075
gene id: 408015:SXIM_RS10075
uniprot id: A0A0F7FSU5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

408015:SXIM RS22840
gene id: 408015:SXIM_RS22840
uniprot id: A0A0F7G078
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

408015:SXIM RS09550
gene id: 408015:SXIM_RS09550
uniprot id: A0A0F7FUB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS15245
gene id: 408015:SXIM_RS15245
uniprot id: A0A0F7FW22
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

408015:SXIM RS14660
gene id: 408015:SXIM_RS14660
uniprot id: A0A0F7FV74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

408015:SXIM RS15965
gene id: 408015:SXIM_RS15965
uniprot id: A0A0F7FVL7
names: Subcellular Location Annotation
messages: Cell membrane

408015:SXIM RS16750
gene id: 408015:SXIM_RS16750
uniprot id: A0A0F7FXP2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

408015:SXIM RS24655
gene id: 408015:SXIM_RS24655
uniprot id: A0A0F7FZR9
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

408015:SXIM RS26955
gene id: 408015:SXIM_RS26955
uniprot id: A0A0F7G0P9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

408015:SXIM RS16345
gene id: 408015:SXIM_RS16345
uniprot id: A0A0F7FWH4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

408015:SXIM RS22700
gene id: 408015:SXIM_RS22700
uniprot id: A0A0F7G054
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

408015:SXIM RS01790
gene id: 408015:SXIM_RS01790
uniprot id: A0A0F7FPK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

408015:SXIM RS02190
gene id: 408015:SXIM_RS02190
uniprot id: A0A0F7FQW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

408015:SXIM RS16905
gene id: 408015:SXIM_RS16905
uniprot id: A0A0F7FXR4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

408015:SXIM RS03635
gene id: 408015:SXIM_RS03635
uniprot id: A0A0F7FRH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

408015:SXIM RS23590
gene id: 408015:SXIM_RS23590
uniprot id: A0A0F7FZN0
names: Similarity
messages: Belongs to the peptidase S33 family.

408015:SXIM RS09585
gene id: 408015:SXIM_RS09585
uniprot id: A0A0F7FUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

408015:SXIM RS00790
gene id: 408015:SXIM_RS00790
uniprot id: A0A0F7FNY7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

408015:SXIM RS17200
gene id: 408015:SXIM_RS17200
uniprot id: A0A0F7FWC0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

408015:SXIM RS20650
gene id: 408015:SXIM_RS20650
uniprot id: A0A0F7FYB0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

408015:SXIM RS05235
gene id: 408015:SXIM_RS05235
uniprot id: A0A0F7FSA9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

408015:SXIM RS00635
gene id: 408015:SXIM_RS00635
uniprot id: A0A0F7CMP4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS24970
gene id: 408015:SXIM_RS24970
uniprot id: A0A0F7G0D6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

408015:SXIM RS01210
gene id: 408015:SXIM_RS01210
uniprot id: A0A0F7FQA4
names: Similarity
messages: Belongs to the AHA1 family.

408015:SXIM RS01835
gene id: 408015:SXIM_RS01835
uniprot id: A0A0F7FQR2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

408015:SXIM RS26365
gene id: 408015:SXIM_RS26365
uniprot id: A0A0F7G0Z0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

408015:SXIM RS10150
gene id: 408015:SXIM_RS10150
uniprot id: A0A0F7FUG2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

408015:SXIM RS24695
gene id: 408015:SXIM_RS24695
uniprot id: A0A0F7FZU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS16775
gene id: 408015:SXIM_RS16775
uniprot id: A0A0F7FW52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

408015:SXIM RS07115
gene id: 408015:SXIM_RS07115
uniprot id: A0A0F7FT19
names: Subcellular Location Annotation
messages: Cytoplasm

408015:SXIM RS08185
gene id: 408015:SXIM_RS08185
uniprot id: A0A0F7CNK1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

408015:SXIM RS06885
gene id: 408015:SXIM_RS06885
uniprot id: A0A0F7FRR4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04185
gene id: 408015:SXIM_RS04185
uniprot id: A0A0F7FRW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

408015:SXIM RS04550
gene id: 408015:SXIM_RS04550
uniprot id: A0A0F7FS15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

408015:SXIM RS11525
gene id: 408015:SXIM_RS11525
uniprot id: A0A0F7CNY4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

408015:SXIM RS25990
gene id: 408015:SXIM_RS25990
uniprot id: A0A0F7G1G9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

408015:SXIM RS02330
gene id: 408015:SXIM_RS02330
uniprot id: A0A0F7FQT7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

408015:SXIM RS13720
gene id: 408015:SXIM_RS13720
uniprot id: A0A0F7FUT2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

408015:SXIM RS17565
gene id: 408015:SXIM_RS17565
uniprot id: A0A0F7CPM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

408015:SXIM RS00760
gene id: 408015:SXIM_RS00760
uniprot id: A0A0F7FNY2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS24200
gene id: 408015:SXIM_RS24200
uniprot id: A0A0F7G0R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS26280
gene id: 408015:SXIM_RS26280
uniprot id: A0A0F7G0K7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

408015:SXIM RS04530
gene id: 408015:SXIM_RS04530
uniprot id: A0A0F7FRW3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

408015:SXIM RS23125
gene id: 408015:SXIM_RS23125
uniprot id: A0A0F7FZH8
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

408015:SXIM RS20955
gene id: 408015:SXIM_RS20955
uniprot id: A0A0F7FYF6
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

408015:SXIM RS21435
gene id: 408015:SXIM_RS21435
uniprot id: A0A0F7FYS8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

408015:SXIM RS10165
gene id: 408015:SXIM_RS10165
uniprot id: A0A0F7FUJ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

408015:SXIM RS20510
gene id: 408015:SXIM_RS20510
uniprot id: A0A0F7FZG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

408015:SXIM RS17860
gene id: 408015:SXIM_RS17860
uniprot id: A0A0F7FXX9
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

408015:SXIM RS19275
gene id: 408015:SXIM_RS19275
uniprot id: A0A0F7FXB2
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS01660
gene id: 408015:SXIM_RS01660
uniprot id: A0A0F7FQH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

408015:SXIM RS05310
gene id: 408015:SXIM_RS05310
uniprot id: A0A0F7FSB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS10620
gene id: 408015:SXIM_RS10620
uniprot id: A0A0F7FT48
names: Similarity
messages: Belongs to the UPF0234 family.

408015:SXIM RS24015
gene id: 408015:SXIM_RS24015
uniprot id: A0A0F7G177
names: Similarity
messages: Belongs to the CFA/CMAS family.

408015:SXIM RS10825
gene id: 408015:SXIM_RS10825
uniprot id: A0A0F7FTJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS25555
gene id: 408015:SXIM_RS25555
uniprot id: A0A0F7G0K9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

408015:SXIM RS19335
gene id: 408015:SXIM_RS19335
uniprot id: A0A0F7CPU8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

408015:SXIM RS10785
gene id: 408015:SXIM_RS10785
uniprot id: A0A0F7FUQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS20425
gene id: 408015:SXIM_RS20425
uniprot id: A0A0F7FXS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

408015:SXIM RS15995
gene id: 408015:SXIM_RS15995
uniprot id: A0A0F7FVM4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

408015:SXIM RS01700
gene id: 408015:SXIM_RS01700
uniprot id: A0A0F7FPC4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

408015:SXIM RS15790
gene id: 408015:SXIM_RS15790
uniprot id: A0A0F7FX92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

408015:SXIM RS18015
gene id: 408015:SXIM_RS18015
uniprot id: A0A0F7FY09
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS07680
gene id: 408015:SXIM_RS07680
uniprot id: A0A0F7CNI0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

408015:SXIM RS11640
gene id: 408015:SXIM_RS11640
uniprot id: A0A0F7FTL7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

408015:SXIM RS17030
gene id: 408015:SXIM_RS17030
uniprot id: A0A0F7FW94
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

408015:SXIM RS06575
gene id: 408015:SXIM_RS06575
uniprot id: A0A0F7FRL8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

408015:SXIM RS15490
gene id: 408015:SXIM_RS15490
uniprot id: A0A0F7FWV1
names: Similarity
messages: Belongs to the HSP15 family.

408015:SXIM RS15090
gene id: 408015:SXIM_RS15090
uniprot id: A0A0F7CPC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

408015:SXIM RS07810
gene id: 408015:SXIM_RS07810
uniprot id: A0A0F7FTE0
names: Similarity
messages: Belongs to the FPG family.

408015:SXIM RS02440
gene id: 408015:SXIM_RS02440
uniprot id: A0A0F7FPD5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

408015:SXIM RS05305
gene id: 408015:SXIM_RS05305
uniprot id: A0A0F7FQQ3
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

408015:SXIM RS05040
gene id: 408015:SXIM_RS05040
uniprot id: A0A0F7CN73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

408015:SXIM RS20565
gene id: 408015:SXIM_RS20565
uniprot id: A0A0F7CPZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS13645
gene id: 408015:SXIM_RS13645
uniprot id: A0A0F7FW03
names: Similarity
messages: Belongs to the peptidase M18 family.

408015:SXIM RS05690
gene id: 408015:SXIM_RS05690
uniprot id: A0A0F7FRD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

408015:SXIM RS01980
gene id: 408015:SXIM_RS01980
uniprot id: A0A0F7CMU7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

408015:SXIM RS02715
gene id: 408015:SXIM_RS02715
uniprot id: A0A0F7FPU4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

408015:SXIM RS09850
gene id: 408015:SXIM_RS09850
uniprot id: A0A0F7FT50
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

408015:SXIM RS18815
gene id: 408015:SXIM_RS18815
uniprot id: A0A0F7FYD7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

408015:SXIM RS06775
gene id: 408015:SXIM_RS06775
uniprot id: A0A0F7FT20
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

408015:SXIM RS27090
gene id: 408015:SXIM_RS27090
uniprot id: A0A0F7CQR3
names: Similarity
messages: Belongs to the peptidase S33 family.

408015:SXIM RS05765
gene id: 408015:SXIM_RS05765
uniprot id: A0A0F7FR01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

408015:SXIM RS21760
gene id: 408015:SXIM_RS21760
uniprot id: A0A0F7CQ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

408015:SXIM RS14875
gene id: 408015:SXIM_RS14875
uniprot id: A0A0F7FV27
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

408015:SXIM RS00310
gene id: 408015:SXIM_RS00310
uniprot id: A0A0F7FPX1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

408015:SXIM RS10175
gene id: 408015:SXIM_RS10175
uniprot id: A0A0F7FSW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

408015:SXIM RS05630
gene id: 408015:SXIM_RS05630
uniprot id: A0A0F7FR49
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS18395
gene id: 408015:SXIM_RS18395
uniprot id: A0A0F7FWY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS15185
gene id: 408015:SXIM_RS15185
uniprot id: A0A0F7CPC9
names: Similarity
messages: Belongs to the CsoR family.

408015:SXIM RS03640
gene id: 408015:SXIM_RS03640
uniprot id: A0A0F7FQI8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

408015:SXIM RS12455
gene id: 408015:SXIM_RS12455
uniprot id: A0A0F7CP21
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10080
gene id: 408015:SXIM_RS10080
uniprot id: A0A0F7FUF2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

408015:SXIM RS16950
gene id: 408015:SXIM_RS16950
uniprot id: A0A0F7FW26
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS25250
gene id: 408015:SXIM_RS25250
uniprot id: A0A0F7G0H3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Secreted

408015:SXIM RS24025
gene id: 408015:SXIM_RS24025
uniprot id: A0A0F7G0P5
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS22075
gene id: 408015:SXIM_RS22075
uniprot id: A0A0F7G0A9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

408015:SXIM RS12400
gene id: 408015:SXIM_RS12400
uniprot id: A0A0F7FTZ9
names: Similarity
messages: Belongs to the YoeB family.

408015:SXIM RS16865
gene id: 408015:SXIM_RS16865
uniprot id: A0A0F7CPJ8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

408015:SXIM RS01680
gene id: 408015:SXIM_RS01680
uniprot id: A0A0F7CMT6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS18090
gene id: 408015:SXIM_RS18090
uniprot id: A0A0F7CPP7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

408015:SXIM RS05190
gene id: 408015:SXIM_RS05190
uniprot id: A0A0F7CN79
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

408015:SXIM RS21425
gene id: 408015:SXIM_RS21425
uniprot id: A0A0F7FZN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

408015:SXIM RS20905
gene id: 408015:SXIM_RS20905
uniprot id: A0A0F7FY10
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

408015:SXIM RS21735
gene id: 408015:SXIM_RS21735
uniprot id: A0A0F7CQ46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

408015:SXIM RS09755
gene id: 408015:SXIM_RS09755
uniprot id: A0A0F7FT42
names: Similarity
messages: Belongs to the transketolase family.

408015:SXIM RS20105
gene id: 408015:SXIM_RS20105
uniprot id: A0A0F7FXP1
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

408015:SXIM RS04470
gene id: 408015:SXIM_RS04470
uniprot id: A0A0F7CN49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

408015:SXIM RS10085
gene id: 408015:SXIM_RS10085
uniprot id: A0A0F7FTM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

408015:SXIM RS13240
gene id: 408015:SXIM_RS13240
uniprot id: A0A0F7FVV3
names: Similarity
messages: Belongs to the thioredoxin family.

408015:SXIM RS10265
gene id: 408015:SXIM_RS10265
uniprot id: A0A0F7FSY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

408015:SXIM RS24730
gene id: 408015:SXIM_RS24730
uniprot id: A0A0F7G118
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

408015:SXIM RS22135
gene id: 408015:SXIM_RS22135
uniprot id: A0A0F7CQ62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

408015:SXIM RS25155
gene id: 408015:SXIM_RS25155
uniprot id: A0A0F7CQI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

408015:SXIM RS23575
gene id: 408015:SXIM_RS23575
uniprot id: A0A0F7CQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS21075
gene id: 408015:SXIM_RS21075
uniprot id: A0A0F7FYI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS10830
gene id: 408015:SXIM_RS10830
uniprot id: A0A0F7CNV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS25120
gene id: 408015:SXIM_RS25120
uniprot id: A0A0F7G163
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

408015:SXIM RS21665
gene id: 408015:SXIM_RS21665
uniprot id: A0A0F7FYE4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

408015:SXIM RS08735
gene id: 408015:SXIM_RS08735
uniprot id: A0A0F7FSS4
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

408015:SXIM RS24030
gene id: 408015:SXIM_RS24030
uniprot id: A0A0F7CQD9
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

408015:SXIM RS12610
gene id: 408015:SXIM_RS12610
uniprot id: A0A0F7FU27
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

408015:SXIM RS09050
gene id: 408015:SXIM_RS09050
uniprot id: A0A0F7FTZ4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

408015:SXIM RS16080
gene id: 408015:SXIM_RS16080
uniprot id: A0A0F7FXD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS13575
gene id: 408015:SXIM_RS13575
uniprot id: A0A0F7CP65
names: Similarity
messages: Belongs to the pirin family.

408015:SXIM RS15730
gene id: 408015:SXIM_RS15730
uniprot id: A0A0F7FX85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

408015:SXIM RS19405
gene id: 408015:SXIM_RS19405
uniprot id: A0A0F7FYY0
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

408015:SXIM RS24790
gene id: 408015:SXIM_RS24790
uniprot id: A0A0F7G0B4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

408015:SXIM RS19180
gene id: 408015:SXIM_RS19180
uniprot id: A0A0F7FYJ0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

408015:SXIM RS20900
gene id: 408015:SXIM_RS20900
uniprot id: A0A0F7FZM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

408015:SXIM RS10820
gene id: 408015:SXIM_RS10820
uniprot id: A0A0F7FTY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS24425
gene id: 408015:SXIM_RS24425
uniprot id: A0A0F7CQF4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

408015:SXIM RS24915
gene id: 408015:SXIM_RS24915
uniprot id: A0A0F7FZV6
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04920
gene id: 408015:SXIM_RS04920
uniprot id: A0A0F7FR25
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS16820
gene id: 408015:SXIM_RS16820
uniprot id: A0A0F7FW04
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

408015:SXIM RS17105
gene id: 408015:SXIM_RS17105
uniprot id: A0A0F7CPK7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

408015:SXIM RS02555
gene id: 408015:SXIM_RS02555
uniprot id: A0A0F7FPP4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

408015:SXIM RS01690
gene id: 408015:SXIM_RS01690
uniprot id: A0A0F7FQI4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

408015:SXIM RS09415
gene id: 408015:SXIM_RS09415
uniprot id: A0A0F7CNQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

408015:SXIM RS08085
gene id: 408015:SXIM_RS08085
uniprot id: A0A0F7FSJ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

408015:SXIM RS03720
gene id: 408015:SXIM_RS03720
uniprot id: A0A0F7FRJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

408015:SXIM RS02100
gene id: 408015:SXIM_RS02100
uniprot id: A0A0F7CMV2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

408015:SXIM RS09045
gene id: 408015:SXIM_RS09045
uniprot id: A0A0F7CNN5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

408015:SXIM RS13245
gene id: 408015:SXIM_RS13245
uniprot id: A0A0F7FV57
names: Similarity
messages: Belongs to the ParB family.

408015:SXIM RS09610
gene id: 408015:SXIM_RS09610
uniprot id: A0A0F7FUC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

408015:SXIM RS22835
gene id: 408015:SXIM_RS22835
uniprot id: A0A0F7FYY6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS11190
gene id: 408015:SXIM_RS11190
uniprot id: A0A0F7FTP7
names: Similarity
messages: Belongs to the Nth/MutY family.

408015:SXIM RS21025
gene id: 408015:SXIM_RS21025
uniprot id: A0A0F7FY33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

408015:SXIM RS04435
gene id: 408015:SXIM_RS04435
uniprot id: A0A0F7FRV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

408015:SXIM RS22985
gene id: 408015:SXIM_RS22985
uniprot id: A0A0F7FZ12
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

408015:SXIM RS01145
gene id: 408015:SXIM_RS01145
uniprot id: A0A0F7FQ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS19190
gene id: 408015:SXIM_RS19190
uniprot id: A0A0F7FXA0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

408015:SXIM RS25355
gene id: 408015:SXIM_RS25355
uniprot id: A0A0F7G006
names: Similarity
messages: Belongs to the terpene synthase family.

408015:SXIM RS26215
gene id: 408015:SXIM_RS26215
uniprot id: A0A0F7G0X2
names: Similarity
messages: Belongs to the IMPACT family.

408015:SXIM RS22560
gene id: 408015:SXIM_RS22560
uniprot id: A0A0F7G0N7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

408015:SXIM RS09845
gene id: 408015:SXIM_RS09845
uniprot id: A0A0F7CNR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

408015:SXIM RS10455
gene id: 408015:SXIM_RS10455
uniprot id: A0A0F7FUM9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10205
gene id: 408015:SXIM_RS10205
uniprot id: A0A0F7FSW5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

408015:SXIM RS25500
gene id: 408015:SXIM_RS25500
uniprot id: A0A0F7G055
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

408015:SXIM RS01780
gene id: 408015:SXIM_RS01780
uniprot id: A0A0F7CMU0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

408015:SXIM RS25190
gene id: 408015:SXIM_RS25190
uniprot id: A0A0F7G0G4
names: Similarity
messages: Belongs to the peptidase S1 family.

408015:SXIM RS21625
gene id: 408015:SXIM_RS21625
uniprot id: A0A0F7FYV8
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.

408015:SXIM RS04225
gene id: 408015:SXIM_RS04225
uniprot id: A0A0F7CN39
names: Similarity
messages: Belongs to the DapA family.

408015:SXIM RS17210
gene id: 408015:SXIM_RS17210
uniprot id: A0A0F7CPL1
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS24670
gene id: 408015:SXIM_RS24670
uniprot id: A0A0F7G112
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

408015:SXIM RS19385
gene id: 408015:SXIM_RS19385
uniprot id: A0A0F7CPV0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

408015:SXIM RS07370
gene id: 408015:SXIM_RS07370
uniprot id: A0A0F7CNG7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

408015:SXIM RS08720
gene id: 408015:SXIM_RS08720
uniprot id: A0A0F7FTU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

408015:SXIM RS15550
gene id: 408015:SXIM_RS15550
uniprot id: A0A0F7FWV7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

408015:SXIM RS07195
gene id: 408015:SXIM_RS07195
uniprot id: A0A0F7FT53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS19025
gene id: 408015:SXIM_RS19025
uniprot id: A0A0F7FYG5
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS07105
gene id: 408015:SXIM_RS07105
uniprot id: A0A0F7CNF6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

408015:SXIM RS13315
gene id: 408015:SXIM_RS13315
uniprot id: A0A0F7FV64
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

408015:SXIM RS20965
gene id: 408015:SXIM_RS20965
uniprot id: A0A0F7FZM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

408015:SXIM RS03260
gene id: 408015:SXIM_RS03260
uniprot id: A0A0F7FRC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

408015:SXIM RS04440
gene id: 408015:SXIM_RS04440
uniprot id: A0A0F7FQW2
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

408015:SXIM RS18980
gene id: 408015:SXIM_RS18980
uniprot id: A0A0F7CPT3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

408015:SXIM RS07920
gene id: 408015:SXIM_RS07920
uniprot id: A0A0F7FRV1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

408015:SXIM RS23210
gene id: 408015:SXIM_RS23210
uniprot id: A0A0F7G0D4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

408015:SXIM RS08250
gene id: 408015:SXIM_RS08250
uniprot id: A0A0F7FS04
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS15705
gene id: 408015:SXIM_RS15705
uniprot id: A0A0F7CPF1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

408015:SXIM RS00885
gene id: 408015:SXIM_RS00885
uniprot id: A0A0F7FP87
names: Similarity
messages: Belongs to the MmpS family.

408015:SXIM RS17635
gene id: 408015:SXIM_RS17635
uniprot id: A0A0F7FWG0
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS02300
gene id: 408015:SXIM_RS02300
uniprot id: A0A0F7FQT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

408015:SXIM RS14060
gene id: 408015:SXIM_RS14060
uniprot id: A0A0F7FUN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

408015:SXIM RS10420
gene id: 408015:SXIM_RS10420
uniprot id: A0A0F7CNU1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

408015:SXIM RS23550
gene id: 408015:SXIM_RS23550
uniprot id: A0A0F7CQC0
names: Similarity
messages: Belongs to the DapA family.

408015:SXIM RS11210
gene id: 408015:SXIM_RS11210
uniprot id: A0A0F7FUX9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS22115
gene id: 408015:SXIM_RS22115
uniprot id: A0A0F7FYM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

408015:SXIM RS08985
gene id: 408015:SXIM_RS08985
uniprot id: A0A0F7FSF1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monovalent cation. The ion could be potassium.

408015:SXIM RS09570
gene id: 408015:SXIM_RS09570
uniprot id: A0A0F7FTE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

408015:SXIM RS12880
gene id: 408015:SXIM_RS12880
uniprot id: A0A0F7FV03
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

408015:SXIM RS21355
gene id: 408015:SXIM_RS21355
uniprot id: A0A0F7FZX5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

408015:SXIM RS01555
gene id: 408015:SXIM_RS01555
uniprot id: A0A0F7FPI0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

408015:SXIM RS18920
gene id: 408015:SXIM_RS18920
uniprot id: A0A0F7FYQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

408015:SXIM RS12475
gene id: 408015:SXIM_RS12475
uniprot id: A0A0F7FUC3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

408015:SXIM RS06640
gene id: 408015:SXIM_RS06640
uniprot id: A0A0F7CND7
names: Similarity
messages: Belongs to the aldose epimerase family.

408015:SXIM RS04085
gene id: 408015:SXIM_RS04085
uniprot id: A0A0F7FQH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

408015:SXIM RS18415
gene id: 408015:SXIM_RS18415
uniprot id: A0A0F7FY87
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

408015:SXIM RS19650
gene id: 408015:SXIM_RS19650
uniprot id: A0A0F7FXG9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

408015:SXIM RS25135
gene id: 408015:SXIM_RS25135
uniprot id: A0A0F7FZY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS19355
gene id: 408015:SXIM_RS19355
uniprot id: A0A0F7FYM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

408015:SXIM RS18205
gene id: 408015:SXIM_RS18205
uniprot id: A0A0F7FXA9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

408015:SXIM RS17490
gene id: 408015:SXIM_RS17490
uniprot id: A0A0F7FXR5
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS21795
gene id: 408015:SXIM_RS21795
uniprot id: A0A0F7G063
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

408015:SXIM RS18355
gene id: 408015:SXIM_RS18355
uniprot id: A0A0F7FY81
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

408015:SXIM RS10370
gene id: 408015:SXIM_RS10370
uniprot id: A0A0F7CNT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

408015:SXIM RS15500
gene id: 408015:SXIM_RS15500
uniprot id: A0A0F7FVM5
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

408015:SXIM RS20170
gene id: 408015:SXIM_RS20170
uniprot id: A0A0F7FXQ0
names: Similarity
messages: Belongs to the CsoR family.

408015:SXIM RS02225
gene id: 408015:SXIM_RS02225
uniprot id: A0A0F7FQX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

408015:SXIM RS12225
gene id: 408015:SXIM_RS12225
uniprot id: A0A0F7FVH4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

408015:SXIM RS25055
gene id: 408015:SXIM_RS25055
uniprot id: A0A0F7CQI0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

408015:SXIM RS05720
gene id: 408015:SXIM_RS05720
uniprot id: A0A0F7FR61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

408015:SXIM RS18290
gene id: 408015:SXIM_RS18290
uniprot id: A0A0F7CPQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

408015:SXIM RS08940
gene id: 408015:SXIM_RS08940
uniprot id: A0A0F7FSS7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

408015:SXIM RS20460
gene id: 408015:SXIM_RS20460
uniprot id: A0A0F7FZ57
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

408015:SXIM RS04315
gene id: 408015:SXIM_RS04315
uniprot id: A0A0F7FQU4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

408015:SXIM RS08930
gene id: 408015:SXIM_RS08930
uniprot id: A0A0F7FTX8
names: Similarity
messages: Belongs to the PGI/PMI family.

408015:SXIM RS14900
gene id: 408015:SXIM_RS14900
uniprot id: A0A0F7FWR5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

408015:SXIM RS12995
gene id: 408015:SXIM_RS12995
uniprot id: A0A0F7FU80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

408015:SXIM RS04120
gene id: 408015:SXIM_RS04120
uniprot id: A0A0F7FRS0
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

408015:SXIM RS14275
gene id: 408015:SXIM_RS14275
uniprot id: A0A0F7FWE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

408015:SXIM RS03645
gene id: 408015:SXIM_RS03645
uniprot id: A0A0F7FQA1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

408015:SXIM RS01840
gene id: 408015:SXIM_RS01840
uniprot id: A0A0F7FP42
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

408015:SXIM RS23145
gene id: 408015:SXIM_RS23145
uniprot id: A0A0F7FZ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS04780
gene id: 408015:SXIM_RS04780
uniprot id: A0A0F7FS28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

408015:SXIM RS10190
gene id: 408015:SXIM_RS10190
uniprot id: A0A0F7FTA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

408015:SXIM RS02350
gene id: 408015:SXIM_RS02350
uniprot id: A0A0F7FQZ1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

408015:SXIM RS04015
gene id: 408015:SXIM_RS04015
uniprot id: A0A0F7FQP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

408015:SXIM RS24840
gene id: 408015:SXIM_RS24840
uniprot id: A0A0F7FZW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

408015:SXIM RS06760
gene id: 408015:SXIM_RS06760
uniprot id: A0A0F7FSX8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

408015:SXIM RS05425
gene id: 408015:SXIM_RS05425
uniprot id: A0A0F7FQS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

408015:SXIM RS11855
gene id: 408015:SXIM_RS11855
uniprot id: A0A0F7CNZ8
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

408015:SXIM RS16730
gene id: 408015:SXIM_RS16730
uniprot id: A0A0F7FXD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS23015
gene id: 408015:SXIM_RS23015
uniprot id: A0A0F7FZ16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS18325
gene id: 408015:SXIM_RS18325
uniprot id: A0A0F7FY78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS24525
gene id: 408015:SXIM_RS24525
uniprot id: A0A0F7CQF8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

408015:SXIM RS10270
gene id: 408015:SXIM_RS10270
uniprot id: A0A0F7CNT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

408015:SXIM RS02970
gene id: 408015:SXIM_RS02970
uniprot id: A0A0F7CMY7
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS05800
gene id: 408015:SXIM_RS05800
uniprot id: A0A0F7FSL6
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10645
gene id: 408015:SXIM_RS10645
uniprot id: A0A0F7FUR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

408015:SXIM RS01990
gene id: 408015:SXIM_RS01990
uniprot id: A0A0F7FP64
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

408015:SXIM RS21915
gene id: 408015:SXIM_RS21915
uniprot id: A0A0F7CQ53
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

408015:SXIM RS02205
gene id: 408015:SXIM_RS02205
uniprot id: A0A0F7FQR4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

408015:SXIM RS20520
gene id: 408015:SXIM_RS20520
uniprot id: A0A0F7FXU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

408015:SXIM RS18190
gene id: 408015:SXIM_RS18190
uniprot id: A0A0F7CPQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

408015:SXIM RS10120
gene id: 408015:SXIM_RS10120
uniprot id: A0A0F7FTQ1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

408015:SXIM RS08465
gene id: 408015:SXIM_RS08465
uniprot id: A0A0F7FS26
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

408015:SXIM RS23105
gene id: 408015:SXIM_RS23105
uniprot id: A0A0F7CQA2
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

408015:SXIM RS19605
gene id: 408015:SXIM_RS19605
uniprot id: A0A0F7FXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS12530
gene id: 408015:SXIM_RS12530
uniprot id: A0A0F7FUV7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

408015:SXIM RS12340
gene id: 408015:SXIM_RS12340
uniprot id: A0A0F7FUT1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

408015:SXIM RS21060
gene id: 408015:SXIM_RS21060
uniprot id: A0A0F7FY38
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

408015:SXIM RS05700
gene id: 408015:SXIM_RS05700
uniprot id: A0A0F7FQW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS15330
gene id: 408015:SXIM_RS15330
uniprot id: A0A0F7FVC4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

408015:SXIM RS02665
gene id: 408015:SXIM_RS02665
uniprot id: A0A0F7FPH3
names: Similarity
messages: Belongs to the cytochrome P450 family.

408015:SXIM RS12000
gene id: 408015:SXIM_RS12000
uniprot id: A0A0F7FU41
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

408015:SXIM RS09800
gene id: 408015:SXIM_RS09800
uniprot id: A0A0F7FSQ8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

408015:SXIM RS17735
gene id: 408015:SXIM_RS17735
uniprot id: A0A0F7FXV7
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

408015:SXIM RS02005
gene id: 408015:SXIM_RS02005
uniprot id: A0A0F7CMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS12790
gene id: 408015:SXIM_RS12790
uniprot id: A0A0F7FUZ0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

408015:SXIM RS16605
gene id: 408015:SXIM_RS16605
uniprot id: A0A0F7FWL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

408015:SXIM RS25485
gene id: 408015:SXIM_RS25485
uniprot id: A0A0F7G1B6
names: Similarity
messages: Belongs to the NodU/CmcH family.

408015:SXIM RS08910
gene id: 408015:SXIM_RS08910
uniprot id: A0A0F7FSS6
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS02110
gene id: 408015:SXIM_RS02110
uniprot id: A0A0F7FP85
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

408015:SXIM RS26775
gene id: 408015:SXIM_RS26775
uniprot id: A0A0F7G135
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10395
gene id: 408015:SXIM_RS10395
uniprot id: A0A0F7CNU0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

408015:SXIM RS07470
gene id: 408015:SXIM_RS07470
uniprot id: A0A0F7CNH1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

408015:SXIM RS15200
gene id: 408015:SXIM_RS15200
uniprot id: A0A0F7FX01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

408015:SXIM RS03995
gene id: 408015:SXIM_RS03995
uniprot id: A0A0F7FQF7
names: Similarity
messages: Belongs to the peptidase U62 family.

408015:SXIM RS10390
gene id: 408015:SXIM_RS10390
uniprot id: A0A0F7FT03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

408015:SXIM RS26290
gene id: 408015:SXIM_RS26290
uniprot id: A0A0F7G0E4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS19240
gene id: 408015:SXIM_RS19240
uniprot id: A0A0F7FXS2
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04905
gene id: 408015:SXIM_RS04905
uniprot id: A0A0F7FS62
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

408015:SXIM RS05475
gene id: 408015:SXIM_RS05475
uniprot id: A0A0F7FR32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS22240
gene id: 408015:SXIM_RS22240
uniprot id: A0A0F7FYP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

408015:SXIM RS15120
gene id: 408015:SXIM_RS15120
uniprot id: A0A0F7FV71
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

408015:SXIM RS07310
gene id: 408015:SXIM_RS07310
uniprot id: A0A0F7FT73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

408015:SXIM RS03530
gene id: 408015:SXIM_RS03530
uniprot id: A0A0F7FQG8
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

408015:SXIM RS12920
gene id: 408015:SXIM_RS12920
uniprot id: A0A0F7FUH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

408015:SXIM RS05340
gene id: 408015:SXIM_RS05340
uniprot id: A0A0F7CN85
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

408015:SXIM RS10050
gene id: 408015:SXIM_RS10050
uniprot id: A0A0F7FUE7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

408015:SXIM RS21365
gene id: 408015:SXIM_RS21365
uniprot id: A0A0F7FYB3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

408015:SXIM RS05410
gene id: 408015:SXIM_RS05410
uniprot id: A0A0F7CN88
names: Similarity
messages: Belongs to the CobT family.

408015:SXIM RS20440
gene id: 408015:SXIM_RS20440
uniprot id: A0A0F7CPZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

408015:SXIM RS04720
gene id: 408015:SXIM_RS04720
uniprot id: A0A0F7CN59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

408015:SXIM RS05050
gene id: 408015:SXIM_RS05050
uniprot id: A0A0F7FS85
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS24595
gene id: 408015:SXIM_RS24595
uniprot id: A0A0F7G1H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

408015:SXIM RS17630
gene id: 408015:SXIM_RS17630
uniprot id: A0A0F7FY25
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

408015:SXIM RS08920
gene id: 408015:SXIM_RS08920
uniprot id: A0A0F7FSD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

408015:SXIM RS13945
gene id: 408015:SXIM_RS13945
uniprot id: A0A0F7FW54
names: Similarity
messages: Belongs to the ketopantoate reductase family.

408015:SXIM RS13060
gene id: 408015:SXIM_RS13060
uniprot id: A0A0F7FVS5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

408015:SXIM RS21180
gene id: 408015:SXIM_RS21180
uniprot id: A0A0F7FZI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS03145
gene id: 408015:SXIM_RS03145
uniprot id: A0A0F7CMZ4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

408015:SXIM RS13170
gene id: 408015:SXIM_RS13170
uniprot id: A0A0F7FVX0
names: Similarity
messages: Belongs to the FemABX family.

408015:SXIM RS19090
gene id: 408015:SXIM_RS19090
uniprot id: A0A0F7FXP9
names: Similarity
messages: Belongs to the AHA1 family.

408015:SXIM RS14610
gene id: 408015:SXIM_RS14610
uniprot id: A0A0F7FVN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

408015:SXIM RS25215
gene id: 408015:SXIM_RS25215
uniprot id: A0A0F7G175
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

408015:SXIM RS11180
gene id: 408015:SXIM_RS11180
uniprot id: A0A0F7FUX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

408015:SXIM RS25700
gene id: 408015:SXIM_RS25700
uniprot id: A0A0F7G1D8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

408015:SXIM RS12905
gene id: 408015:SXIM_RS12905
uniprot id: A0A0F7FVQ5
names: Similarity
messages: Belongs to the SCO1/2 family.

408015:SXIM RS21765
gene id: 408015:SXIM_RS21765
uniprot id: A0A0F7G058
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

408015:SXIM RS10915
gene id: 408015:SXIM_RS10915
uniprot id: A0A0F7FTL5
names: Subcellular Location Annotation
messages: Cytoplasm

408015:SXIM RS04975
gene id: 408015:SXIM_RS04975
uniprot id: A0A0F7FR31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

408015:SXIM RS07635
gene id: 408015:SXIM_RS07635
uniprot id: A0A0F7CNH8
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10800
gene id: 408015:SXIM_RS10800
uniprot id: A0A0F7FUT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS22955
gene id: 408015:SXIM_RS22955
uniprot id: A0A0F7FZ05
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

408015:SXIM RS05605
gene id: 408015:SXIM_RS05605
uniprot id: A0A0F7FSG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

408015:SXIM RS20130
gene id: 408015:SXIM_RS20130
uniprot id: A0A0F7FYZ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

408015:SXIM RS17710
gene id: 408015:SXIM_RS17710
uniprot id: A0A0F7FWZ1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

408015:SXIM RS25665
gene id: 408015:SXIM_RS25665
uniprot id: A0A0F7CQK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

408015:SXIM RS05635
gene id: 408015:SXIM_RS05635
uniprot id: A0A0F7CN97
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

408015:SXIM RS26575
gene id: 408015:SXIM_RS26575
uniprot id: A0A0F7CQP1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

408015:SXIM RS04355
gene id: 408015:SXIM_RS04355
uniprot id: A0A0F7FQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS26355
gene id: 408015:SXIM_RS26355
uniprot id: A0A0F7G0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

408015:SXIM RS12385
gene id: 408015:SXIM_RS12385
uniprot id: A0A0F7FVK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

408015:SXIM RS14430
gene id: 408015:SXIM_RS14430
uniprot id: A0A0F7CPA0
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS01655
gene id: 408015:SXIM_RS01655
uniprot id: A0A0F7CMT5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

408015:SXIM RS01740
gene id: 408015:SXIM_RS01740
uniprot id: A0A0F7FQP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

408015:SXIM RS10135
gene id: 408015:SXIM_RS10135
uniprot id: A0A0F7FUJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

408015:SXIM RS13745
gene id: 408015:SXIM_RS13745
uniprot id: A0A0F7FVB3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

408015:SXIM RS11280
gene id: 408015:SXIM_RS11280
uniprot id: A0A0F7FUZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS00745
gene id: 408015:SXIM_RS00745
uniprot id: A0A0F7FNL8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

408015:SXIM RS08975
gene id: 408015:SXIM_RS08975
uniprot id: A0A0F7CNN2
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

408015:SXIM RS04000
gene id: 408015:SXIM_RS04000
uniprot id: A0A0F7FQ35
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

408015:SXIM RS04965
gene id: 408015:SXIM_RS04965
uniprot id: A0A0F7CN70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

408015:SXIM RS16185
gene id: 408015:SXIM_RS16185
uniprot id: A0A0F7CPH0
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS20160
gene id: 408015:SXIM_RS20160
uniprot id: A0A0F7FYZ9
names: Similarity
messages: Belongs to the cytochrome P450 family.

408015:SXIM RS10655
gene id: 408015:SXIM_RS10655
uniprot id: A0A0F7CNV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS19915
gene id: 408015:SXIM_RS19915
uniprot id: A0A0F7FYV5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

408015:SXIM RS03510
gene id: 408015:SXIM_RS03510
uniprot id: A0A0F7FRH9
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

408015:SXIM RS23350
gene id: 408015:SXIM_RS23350
uniprot id: A0A0F7CQB2
names: Similarity
messages: Belongs to the allantoicase family.

408015:SXIM RS08520
gene id: 408015:SXIM_RS08520
uniprot id: A0A0F7FS37
names: Similarity
messages: Belongs to the TPP enzyme family.

408015:SXIM RS06445
gene id: 408015:SXIM_RS06445
uniprot id: A0A0F7FR79
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

408015:SXIM RS05885
gene id: 408015:SXIM_RS05885
uniprot id: A0A0F7FSN0
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

408015:SXIM RS09240
gene id: 408015:SXIM_RS09240
uniprot id: A0A0F7FU15
names: Similarity
messages: Belongs to the ABC transporter superfamily.

408015:SXIM RS22235
gene id: 408015:SXIM_RS22235
uniprot id: A0A0F7CQ66
names: Similarity
messages: Belongs to the EccD/Snm4 family.

408015:SXIM RS15430
gene id: 408015:SXIM_RS15430
uniprot id: A0A0F7FWU4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

408015:SXIM RS14770
gene id: 408015:SXIM_RS14770
uniprot id: A0A0F7CPB3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

408015:SXIM RS13510
gene id: 408015:SXIM_RS13510
uniprot id: A0A0F7FUG0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

408015:SXIM RS25450
gene id: 408015:SXIM_RS25450
uniprot id: A0A0F7G016
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

408015:SXIM RS16395
gene id: 408015:SXIM_RS16395
uniprot id: A0A0F7FVU2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

408015:SXIM RS02705
gene id: 408015:SXIM_RS02705
uniprot id: A0A0F7FR50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

408015:SXIM RS19680
gene id: 408015:SXIM_RS19680
uniprot id: A0A0F7FXH2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

408015:SXIM RS00325
gene id: 408015:SXIM_RS00325
uniprot id: A0A0F7FQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS10155
gene id: 408015:SXIM_RS10155
uniprot id: A0A0F7FTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

408015:SXIM RS01880
gene id: 408015:SXIM_RS01880
uniprot id: A0A0F7CMU4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

408015:SXIM RS24415
gene id: 408015:SXIM_RS24415
uniprot id: A0A0F7G0Y3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

408015:SXIM RS22380
gene id: 408015:SXIM_RS22380
uniprot id: A0A0F7FZ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS21825
gene id: 408015:SXIM_RS21825
uniprot id: A0A0F7G071
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

408015:SXIM RS21615
gene id: 408015:SXIM_RS21615
uniprot id: A0A0F7FYE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

408015:SXIM RS03625
gene id: 408015:SXIM_RS03625
uniprot id: A0A0F7FPY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

408015:SXIM RS18120
gene id: 408015:SXIM_RS18120
uniprot id: A0A0F7FWR8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

408015:SXIM RS24360
gene id: 408015:SXIM_RS24360
uniprot id: A0A0F7FZN2
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS17230
gene id: 408015:SXIM_RS17230
uniprot id: A0A0F7CPL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

408015:SXIM RS08030
gene id: 408015:SXIM_RS08030
uniprot id: A0A0F7FSA6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

408015:SXIM RS18860
gene id: 408015:SXIM_RS18860
uniprot id: A0A0F7FYP2
names: Similarity
messages: Belongs to the universal stress protein A family.

408015:SXIM RS13710
gene id: 408015:SXIM_RS13710
uniprot id: A0A0F7FW13
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

408015:SXIM RS07030
gene id: 408015:SXIM_RS07030
uniprot id: A0A0F7FS30
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

408015:SXIM RS10975
gene id: 408015:SXIM_RS10975
uniprot id: A0A0F7CNW3
names: Similarity
messages: Belongs to the FPG family.

408015:SXIM RS15420
gene id: 408015:SXIM_RS15420
uniprot id: A0A0F7FX34
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

408015:SXIM RS18220
gene id: 408015:SXIM_RS18220
uniprot id: A0A0F7FYD4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS18080
gene id: 408015:SXIM_RS18080
uniprot id: A0A0F7FX56
names: Similarity
messages: Belongs to the catalase family.

408015:SXIM RS04140
gene id: 408015:SXIM_RS04140
uniprot id: A0A0F7FQR5
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

408015:SXIM RS23920
gene id: 408015:SXIM_RS23920
uniprot id: A0A0F7FZG0
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS15540
gene id: 408015:SXIM_RS15540
uniprot id: A0A0F7FX54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS09460
gene id: 408015:SXIM_RS09460
uniprot id: A0A0F7FSY8
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS03210
gene id: 408015:SXIM_RS03210
uniprot id: A0A0F7FQB4
names: Similarity
messages: Belongs to the TPP enzyme family.

408015:SXIM RS04130
gene id: 408015:SXIM_RS04130
uniprot id: A0A0F7CN35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

408015:SXIM RS11585
gene id: 408015:SXIM_RS11585
uniprot id: A0A0F7FV44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

408015:SXIM RS08475
gene id: 408015:SXIM_RS08475
uniprot id: A0A0F7CNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS22845
gene id: 408015:SXIM_RS22845
uniprot id: A0A0F7FZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

408015:SXIM RS23960
gene id: 408015:SXIM_RS23960
uniprot id: A0A0F7G0N6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

408015:SXIM RS14855
gene id: 408015:SXIM_RS14855
uniprot id: A0A0F7FVS1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

408015:SXIM RS12235
gene id: 408015:SXIM_RS12235
uniprot id: A0A0F7FVF8
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS15510
gene id: 408015:SXIM_RS15510
uniprot id: A0A0F7FX49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

408015:SXIM RS01545
gene id: 408015:SXIM_RS01545
uniprot id: A0A0F7CMT0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

408015:SXIM RS25225
gene id: 408015:SXIM_RS25225
uniprot id: A0A0F7G018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS11925
gene id: 408015:SXIM_RS11925
uniprot id: A0A0F7FVA8
names: Similarity
messages: Belongs to the cytochrome P450 family.

408015:SXIM RS26595
gene id: 408015:SXIM_RS26595
uniprot id: A0A0F7G0Q1
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS11320
gene id: 408015:SXIM_RS11320
uniprot id: A0A0F7FTR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS16780
gene id: 408015:SXIM_RS16780
uniprot id: A0A0F7FXP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

408015:SXIM RS23990
gene id: 408015:SXIM_RS23990
uniprot id: A0A0F7FZH0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

408015:SXIM RS21100
gene id: 408015:SXIM_RS21100
uniprot id: A0A0F7FZH2
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS00575
gene id: 408015:SXIM_RS00575
uniprot id: A0A0F7FQ57
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS17750
gene id: 408015:SXIM_RS17750
uniprot id: A0A0F7FWM2
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

408015:SXIM RS01720
gene id: 408015:SXIM_RS01720
uniprot id: A0A0F7FQJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS24660
gene id: 408015:SXIM_RS24660
uniprot id: A0A0F7G1I2
names: Similarity
messages: Belongs to the PrpD family.

408015:SXIM RS16330
gene id: 408015:SXIM_RS16330
uniprot id: A0A0F7FXH1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

408015:SXIM RS06165
gene id: 408015:SXIM_RS06165
uniprot id: A0A0F7FSS0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

408015:SXIM RS25495
gene id: 408015:SXIM_RS25495
uniprot id: A0A0F7CQJ8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

408015:SXIM RS03060
gene id: 408015:SXIM_RS03060
uniprot id: A0A0F7FQ07
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

408015:SXIM RS19800
gene id: 408015:SXIM_RS19800
uniprot id: A0A0F7FXJ1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

408015:SXIM RS22030
gene id: 408015:SXIM_RS22030
uniprot id: A0A0F7FZW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS00950
gene id: 408015:SXIM_RS00950
uniprot id: A0A0F7FP12
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

408015:SXIM RS27950
gene id: 408015:SXIM_RS27950
uniprot id: A0A0F7FQA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

408015:SXIM RS17245
gene id: 408015:SXIM_RS17245
uniprot id: A0A0F7FXM0
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

408015:SXIM RS04790
gene id: 408015:SXIM_RS04790
uniprot id: A0A0F7FQT6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

408015:SXIM RS08935
gene id: 408015:SXIM_RS08935
uniprot id: A0A0F7FT17
names: Similarity
messages: Belongs to the UPF0434 family.

408015:SXIM RS13145
gene id: 408015:SXIM_RS13145
uniprot id: A0A0F7FUA3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

408015:SXIM RS02180
gene id: 408015:SXIM_RS02180
uniprot id: A0A0F7FPQ9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

408015:SXIM RS05065
gene id: 408015:SXIM_RS05065
uniprot id: A0A0F7CN74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

408015:SXIM RS11580
gene id: 408015:SXIM_RS11580
uniprot id: A0A0F7FTK7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

408015:SXIM RS14240
gene id: 408015:SXIM_RS14240
uniprot id: A0A0F7FV09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS18470
gene id: 408015:SXIM_RS18470
uniprot id: A0A0F7FWV8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

408015:SXIM RS23935
gene id: 408015:SXIM_RS23935
uniprot id: A0A0F7FZT1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

408015:SXIM RS07730
gene id: 408015:SXIM_RS07730
uniprot id: A0A0F7FS63
names: Similarity
messages: Belongs to the EccD/Snm4 family.

408015:SXIM RS02000
gene id: 408015:SXIM_RS02000
uniprot id: A0A0F7FPN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

408015:SXIM RS12670
gene id: 408015:SXIM_RS12670
uniprot id: A0A0F7FU33
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

408015:SXIM RS25305
gene id: 408015:SXIM_RS25305
uniprot id: A0A0F7G189
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS03675
gene id: 408015:SXIM_RS03675
uniprot id: A0A0F7CN17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

408015:SXIM RS00600
gene id: 408015:SXIM_RS00600
uniprot id: A0A0F7CMP2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

408015:SXIM RS22695
gene id: 408015:SXIM_RS22695
uniprot id: A0A0F7CQ85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS16140
gene id: 408015:SXIM_RS16140
uniprot id: A0A0F7CPG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

408015:SXIM RS23020
gene id: 408015:SXIM_RS23020
uniprot id: A0A0F7G0A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

408015:SXIM RS10815
gene id: 408015:SXIM_RS10815
uniprot id: A0A0F7FUR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS04060
gene id: 408015:SXIM_RS04060
uniprot id: A0A0F7FRQ8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

408015:SXIM RS10435
gene id: 408015:SXIM_RS10435
uniprot id: A0A0F7FUK3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

408015:SXIM RS18330
gene id: 408015:SXIM_RS18330
uniprot id: A0A0F7FXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS06235
gene id: 408015:SXIM_RS06235
uniprot id: A0A0F7FR55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

408015:SXIM RS25980
gene id: 408015:SXIM_RS25980
uniprot id: A0A0F7G259
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS24700
gene id: 408015:SXIM_RS24700
uniprot id: A0A0F7CQG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS21290
gene id: 408015:SXIM_RS21290
uniprot id: A0A0F7FY99
names: Similarity
messages: Belongs to the Dps family.

408015:SXIM RS13290
gene id: 408015:SXIM_RS13290
uniprot id: A0A0F7FUM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

408015:SXIM RS04875
gene id: 408015:SXIM_RS04875
uniprot id: A0A0F7FS57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

408015:SXIM RS00840
gene id: 408015:SXIM_RS00840
uniprot id: A0A0F7FQ51
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

408015:SXIM RS16840
gene id: 408015:SXIM_RS16840
uniprot id: A0A0F7CPJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

408015:SXIM RS21095
gene id: 408015:SXIM_RS21095
uniprot id: A0A0F7CQ20
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

408015:SXIM RS03935
gene id: 408015:SXIM_RS03935
uniprot id: A0A0F7FQE7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

408015:SXIM RS05660
gene id: 408015:SXIM_RS05660
uniprot id: A0A0F7CN98
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

408015:SXIM RS10470
gene id: 408015:SXIM_RS10470
uniprot id: A0A0F7FTU6
names: Similarity
messages: Belongs to the UPF0336 family.

408015:SXIM RS25850
gene id: 408015:SXIM_RS25850
uniprot id: A0A0F7G077
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS23915
gene id: 408015:SXIM_RS23915
uniprot id: A0A0F7G161
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

408015:SXIM RS10170
gene id: 408015:SXIM_RS10170
uniprot id: A0A0F7CNT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

408015:SXIM RS17125
gene id: 408015:SXIM_RS17125
uniprot id: A0A0F7FWR7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

408015:SXIM RS24685
gene id: 408015:SXIM_RS24685
uniprot id: A0A0F7FZS4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

408015:SXIM RS23910
gene id: 408015:SXIM_RS23910
uniprot id: A0A0F7FZD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS21995
gene id: 408015:SXIM_RS21995
uniprot id: A0A0F7FYK6
names: Similarity
messages: Belongs to the CdaR family.

408015:SXIM RS25310
gene id: 408015:SXIM_RS25310
uniprot id: A0A0F7G0I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS14860
gene id: 408015:SXIM_RS14860
uniprot id: A0A0F7FV95
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

408015:SXIM RS07660
gene id: 408015:SXIM_RS07660
uniprot id: A0A0F7FSC7
names: Similarity
messages: Belongs to the peptidase S26 family.

408015:SXIM RS07605
gene id: 408015:SXIM_RS07605
uniprot id: A0A0F7FSB8
names: Similarity
messages: Belongs to the MreC family.

408015:SXIM RS17315
gene id: 408015:SXIM_RS17315
uniprot id: A0A0F7FXY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

408015:SXIM RS18435
gene id: 408015:SXIM_RS18435
uniprot id: A0A0F7CPR1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

408015:SXIM RS24350
gene id: 408015:SXIM_RS24350
uniprot id: A0A0F7G0X0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

408015:SXIM RS01635
gene id: 408015:SXIM_RS01635
uniprot id: A0A0F7FPJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS25045
gene id: 408015:SXIM_RS25045
uniprot id: A0A0F7G1T5
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

408015:SXIM RS10720
gene id: 408015:SXIM_RS10720
uniprot id: A0A0F7FUP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

408015:SXIM RS02355
gene id: 408015:SXIM_RS02355
uniprot id: A0A0F7FPC1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

408015:SXIM RS10650
gene id: 408015:SXIM_RS10650
uniprot id: A0A0F7FT51
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04600
gene id: 408015:SXIM_RS04600
uniprot id: A0A0F7FQY3
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS20505
gene id: 408015:SXIM_RS20505
uniprot id: A0A0F7FXV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

408015:SXIM RS26635
gene id: 408015:SXIM_RS26635
uniprot id: A0A0F7G2E8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

408015:SXIM RS02275
gene id: 408015:SXIM_RS02275
uniprot id: A0A0F7FPS0
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10635
gene id: 408015:SXIM_RS10635
uniprot id: A0A0F7FTW3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

408015:SXIM RS26260
gene id: 408015:SXIM_RS26260
uniprot id: A0A0F7G0D9
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

408015:SXIM RS22110
gene id: 408015:SXIM_RS22110
uniprot id: A0A0F7CQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

408015:SXIM RS14620
gene id: 408015:SXIM_RS14620
uniprot id: A0A0F7CPA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

408015:SXIM RS21650
gene id: 408015:SXIM_RS21650
uniprot id: A0A0F7FZR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

408015:SXIM RS25325
gene id: 408015:SXIM_RS25325
uniprot id: A0A0F7CQJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

408015:SXIM RS01855
gene id: 408015:SXIM_RS01855
uniprot id: A0A0F7CMU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

408015:SXIM RS13155
gene id: 408015:SXIM_RS13155
uniprot id: A0A0F7CP49
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS03340
gene id: 408015:SXIM_RS03340
uniprot id: A0A0F7FRF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

408015:SXIM RS21670
gene id: 408015:SXIM_RS21670
uniprot id: A0A0F7G044
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

408015:SXIM RS01430
gene id: 408015:SXIM_RS01430
uniprot id: A0A0F7FP86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

408015:SXIM RS26770
gene id: 408015:SXIM_RS26770
uniprot id: A0A0F7CQP9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS08090
gene id: 408015:SXIM_RS08090
uniprot id: A0A0F7FSB5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

408015:SXIM RS00430
gene id: 408015:SXIM_RS00430
uniprot id: A0A0F7CMN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS09190
gene id: 408015:SXIM_RS09190
uniprot id: A0A0F7FSV5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

408015:SXIM RS16095
gene id: 408015:SXIM_RS16095
uniprot id: A0A0F7FX36
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

408015:SXIM RS21645
gene id: 408015:SXIM_RS21645
uniprot id: A0A0F7FYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

408015:SXIM RS02075
gene id: 408015:SXIM_RS02075
uniprot id: A0A0F7FQU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

408015:SXIM RS08380
gene id: 408015:SXIM_RS08380
uniprot id: A0A0F7CNK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

408015:SXIM RS16715
gene id: 408015:SXIM_RS16715
uniprot id: A0A0F7CPJ2
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

408015:SXIM RS00820
gene id: 408015:SXIM_RS00820
uniprot id: A0A0F7FNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS15055
gene id: 408015:SXIM_RS15055
uniprot id: A0A0F7FV62
names: Similarity
messages: Belongs to the peptidase S8 family.

408015:SXIM RS02210
gene id: 408015:SXIM_RS02210
uniprot id: A0A0F7FPR3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

408015:SXIM RS27040
gene id: 408015:SXIM_RS27040
uniprot id: A0A0F7G0W3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

408015:SXIM RS24020
gene id: 408015:SXIM_RS24020
uniprot id: A0A0F7FZH4
names: Similarity
messages: Belongs to the CFA/CMAS family.

408015:SXIM RS22435
gene id: 408015:SXIM_RS22435
uniprot id: A0A0F7CQ74
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

408015:SXIM RS00140
gene id: 408015:SXIM_RS00140
uniprot id: A0A0F7FNW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

408015:SXIM RS18940
gene id: 408015:SXIM_RS18940
uniprot id: A0A0F7FXM8
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS21265
gene id: 408015:SXIM_RS21265
uniprot id: A0A0F7FZV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

408015:SXIM RS04970
gene id: 408015:SXIM_RS04970
uniprot id: A0A0F7FS65
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

408015:SXIM RS07630
gene id: 408015:SXIM_RS07630
uniprot id: A0A0F7FSC1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

408015:SXIM RS22040
gene id: 408015:SXIM_RS22040
uniprot id: A0A0F7CQ58
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

408015:SXIM RS21810
gene id: 408015:SXIM_RS21810
uniprot id: A0A0F7CQ49
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

408015:SXIM RS03810
gene id: 408015:SXIM_RS03810
uniprot id: A0A0F7FQ10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS15170
gene id: 408015:SXIM_RS15170
uniprot id: A0A0F7FVG7
names: Similarity
messages: Belongs to the peptidase C40 family.

408015:SXIM RS26395
gene id: 408015:SXIM_RS26395
uniprot id: A0A0F7CQN4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS25830
gene id: 408015:SXIM_RS25830
uniprot id: A0A0F7G0P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

408015:SXIM RS17310
gene id: 408015:SXIM_RS17310
uniprot id: A0A0F7FWE9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS18855
gene id: 408015:SXIM_RS18855
uniprot id: A0A0F7FX57
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

408015:SXIM RS03650
gene id: 408015:SXIM_RS03650
uniprot id: A0A0F7CN16
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

408015:SXIM RS18960
gene id: 408015:SXIM_RS18960
uniprot id: A0A0F7FX26
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

408015:SXIM RS03240
gene id: 408015:SXIM_RS03240
uniprot id: A0A0F7CMZ8
names: Similarity
messages: Belongs to the pirin family.

408015:SXIM RS15210
gene id: 408015:SXIM_RS15210
uniprot id: A0A0F7CPD0
names: Similarity
messages: Belongs to the peptidase S8 family.

408015:SXIM RS16470
gene id: 408015:SXIM_RS16470
uniprot id: A0A0F7FWJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

408015:SXIM RS24950
gene id: 408015:SXIM_RS24950
uniprot id: A0A0F7G1S0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

408015:SXIM RS18670
gene id: 408015:SXIM_RS18670
uniprot id: A0A0F7FX28
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

408015:SXIM RS20095
gene id: 408015:SXIM_RS20095
uniprot id: A0A0F7CPX9
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

408015:SXIM RS08260
gene id: 408015:SXIM_RS08260
uniprot id: A0A0F7CNK4
names: Similarity
messages: Belongs to the GSP E family.

408015:SXIM RS25800
gene id: 408015:SXIM_RS25800
uniprot id: A0A0F7G0P3
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS12100
gene id: 408015:SXIM_RS12100
uniprot id: A0A0F7CP07
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

408015:SXIM RS11480
gene id: 408015:SXIM_RS11480
uniprot id: A0A0F7FV40
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS18300
gene id: 408015:SXIM_RS18300
uniprot id: A0A0F7FXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS25600
gene id: 408015:SXIM_RS25600
uniprot id: A0A0F7G211
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

408015:SXIM RS16525
gene id: 408015:SXIM_RS16525
uniprot id: A0A0F7CPI4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

408015:SXIM RS22360
gene id: 408015:SXIM_RS22360
uniprot id: A0A0F7G0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

408015:SXIM RS12045
gene id: 408015:SXIM_RS12045
uniprot id: A0A0F7CP05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

408015:SXIM RS11735
gene id: 408015:SXIM_RS11735
uniprot id: A0A0F7FUD8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

408015:SXIM RS04715
gene id: 408015:SXIM_RS04715
uniprot id: A0A0F7FRZ6
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS24825
gene id: 408015:SXIM_RS24825
uniprot id: A0A0F7FZU4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

408015:SXIM RS09350
gene id: 408015:SXIM_RS09350
uniprot id: A0A0F7FSJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

408015:SXIM RS13395
gene id: 408015:SXIM_RS13395
uniprot id: A0A0F7FUN4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04650
gene id: 408015:SXIM_RS04650
uniprot id: A0A0F7FQE2
names: Similarity
messages: Belongs to the group II decarboxylase family.

408015:SXIM RS05025
gene id: 408015:SXIM_RS05025
uniprot id: A0A0F7FQK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS07890
gene id: 408015:SXIM_RS07890
uniprot id: A0A0F7FRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

408015:SXIM RS01640
gene id: 408015:SXIM_RS01640
uniprot id: A0A0F7FPB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

408015:SXIM RS03850
gene id: 408015:SXIM_RS03850
uniprot id: A0A0F7CN24
names: Similarity
messages: Belongs to the IucA/IucC family.

408015:SXIM RS10745
gene id: 408015:SXIM_RS10745
uniprot id: A0A0F7FT63
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

408015:SXIM RS07350
gene id: 408015:SXIM_RS07350
uniprot id: A0A0F7FRK9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04990
gene id: 408015:SXIM_RS04990
uniprot id: A0A0F7CN71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

408015:SXIM RS10195
gene id: 408015:SXIM_RS10195
uniprot id: A0A0F7CNT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

408015:SXIM RS07095
gene id: 408015:SXIM_RS07095
uniprot id: A0A0F7FRU6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

408015:SXIM RS10945
gene id: 408015:SXIM_RS10945
uniprot id: A0A0F7FTL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

408015:SXIM RS08815
gene id: 408015:SXIM_RS08815
uniprot id: A0A0F7CNM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

408015:SXIM RS11970
gene id: 408015:SXIM_RS11970
uniprot id: A0A0F7FTV0
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

408015:SXIM RS10340
gene id: 408015:SXIM_RS10340
uniprot id: A0A0F7FTT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

408015:SXIM RS06355
gene id: 408015:SXIM_RS06355
uniprot id: A0A0F7CNC6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

408015:SXIM RS02390
gene id: 408015:SXIM_RS02390
uniprot id: A0A0F7FQU9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

408015:SXIM RS04745
gene id: 408015:SXIM_RS04745
uniprot id: A0A0F7CN60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

408015:SXIM RS21925
gene id: 408015:SXIM_RS21925
uniprot id: A0A0F7G086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS19035
gene id: 408015:SXIM_RS19035
uniprot id: A0A0F7FX82
names: Similarity
messages: Belongs to the Nudix hydrolase family.

408015:SXIM RS26560
gene id: 408015:SXIM_RS26560
uniprot id: A0A0F7G114
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

408015:SXIM RS02420
gene id: 408015:SXIM_RS02420
uniprot id: A0A0F7FQV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

408015:SXIM RS03680
gene id: 408015:SXIM_RS03680
uniprot id: A0A0F7FRK3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

408015:SXIM RS05510
gene id: 408015:SXIM_RS05510
uniprot id: A0A0F7CN92
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

408015:SXIM RS10240
gene id: 408015:SXIM_RS10240
uniprot id: A0A0F7FUH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

408015:SXIM RS06740
gene id: 408015:SXIM_RS06740
uniprot id: A0A0F7FRP1
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

408015:SXIM RS01140
gene id: 408015:SXIM_RS01140
uniprot id: A0A0F7FNS4
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

408015:SXIM RS25345
gene id: 408015:SXIM_RS25345
uniprot id: A0A0F7CQJ2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

408015:SXIM RS22035
gene id: 408015:SXIM_RS22035
uniprot id: A0A0F7FZ18
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

408015:SXIM RS20080
gene id: 408015:SXIM_RS20080
uniprot id: A0A0F7FZ96
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

408015:SXIM RS12495
gene id: 408015:SXIM_RS12495
uniprot id: A0A0F7FVJ3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

408015:SXIM RS18965
gene id: 408015:SXIM_RS18965
uniprot id: A0A0F7FYF7
names: Similarity
messages: Belongs to the catalase family.

408015:SXIM RS22245
gene id: 408015:SXIM_RS22245
uniprot id: A0A0F7FZ47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

408015:SXIM RS17620
gene id: 408015:SXIM_RS17620
uniprot id: A0A0F7CPM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

408015:SXIM RS26640
gene id: 408015:SXIM_RS26640
uniprot id: A0A0F7G0J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS19555
gene id: 408015:SXIM_RS19555
uniprot id: A0A0F7FXW9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS16975
gene id: 408015:SXIM_RS16975
uniprot id: A0A0F7FXS4
names: Similarity
messages: Belongs to the YciI family.

408015:SXIM RS08830
gene id: 408015:SXIM_RS08830
uniprot id: A0A0F7FSV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

408015:SXIM RS26420
gene id: 408015:SXIM_RS26420
uniprot id: A0A0F7CQN5
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS03610
gene id: 408015:SXIM_RS03610
uniprot id: A0A0F7CN14
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

408015:SXIM RS24935
gene id: 408015:SXIM_RS24935
uniprot id: A0A0F7G139
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

408015:SXIM RS00715
gene id: 408015:SXIM_RS00715
uniprot id: A0A0F7FNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

408015:SXIM RS10060
gene id: 408015:SXIM_RS10060
uniprot id: A0A0F7FT80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

408015:SXIM RS13390
gene id: 408015:SXIM_RS13390
uniprot id: A0A0F7CP58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

408015:SXIM RS19720
gene id: 408015:SXIM_RS19720
uniprot id: A0A0F7FZ32
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

408015:SXIM RS07235
gene id: 408015:SXIM_RS07235
uniprot id: A0A0F7FRJ0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

408015:SXIM RS17440
gene id: 408015:SXIM_RS17440
uniprot id: A0A0F7FXZ9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

408015:SXIM RS28085
gene id: 408015:SXIM_RS28085
uniprot id: A0A0F7FVD9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS05670
gene id: 408015:SXIM_RS05670
uniprot id: A0A0F7FSH4
names: Similarity
messages: Belongs to the terpene synthase family.

408015:SXIM RS00425
gene id: 408015:SXIM_RS00425
uniprot id: A0A0F7FNH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS02345
gene id: 408015:SXIM_RS02345
uniprot id: A0A0F7CMW2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

408015:SXIM RS04300
gene id: 408015:SXIM_RS04300
uniprot id: A0A0F7FRY2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

408015:SXIM RS05680
gene id: 408015:SXIM_RS05680
uniprot id: A0A0F7FSH7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

408015:SXIM RS04195
gene id: 408015:SXIM_RS04195
uniprot id: A0A0F7FRR7
names: Similarity
messages: Belongs to the DapA family.

408015:SXIM RS09665
gene id: 408015:SXIM_RS09665
uniprot id: A0A0F7FUC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS07970
gene id: 408015:SXIM_RS07970
uniprot id: A0A0F7CNJ2
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

408015:SXIM RS04740
gene id: 408015:SXIM_RS04740
uniprot id: A0A0F7FQF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

408015:SXIM RS13295
gene id: 408015:SXIM_RS13295
uniprot id: A0A0F7FVY4
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

408015:SXIM RS09920
gene id: 408015:SXIM_RS09920
uniprot id: A0A0F7FSS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

408015:SXIM RS04895
gene id: 408015:SXIM_RS04895
uniprot id: A0A0F7FQV6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

408015:SXIM RS10305
gene id: 408015:SXIM_RS10305
uniprot id: A0A0F7FUI9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

408015:SXIM RS23665
gene id: 408015:SXIM_RS23665
uniprot id: A0A0F7FZC1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

408015:SXIM RS07400
gene id: 408015:SXIM_RS07400
uniprot id: A0A0F7FRZ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

408015:SXIM RS20525
gene id: 408015:SXIM_RS20525
uniprot id: A0A0F7FZ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

408015:SXIM RS14970
gene id: 408015:SXIM_RS14970
uniprot id: A0A0F7FV45
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS02095
gene id: 408015:SXIM_RS02095
uniprot id: A0A0F7FPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

408015:SXIM RS12945
gene id: 408015:SXIM_RS12945
uniprot id: A0A0F7FV12
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS22280
gene id: 408015:SXIM_RS22280
uniprot id: A0A0F7FYN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

408015:SXIM RS17485
gene id: 408015:SXIM_RS17485
uniprot id: A0A0F7FWC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

408015:SXIM RS06680
gene id: 408015:SXIM_RS06680
uniprot id: A0A0F7FRA9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

408015:SXIM RS04810
gene id: 408015:SXIM_RS04810
uniprot id: A0A0F7FR09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS23185
gene id: 408015:SXIM_RS23185
uniprot id: A0A0F7FZI8
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

408015:SXIM RS13400
gene id: 408015:SXIM_RS13400
uniprot id: A0A0F7FVZ6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

408015:SXIM RS10210
gene id: 408015:SXIM_RS10210
uniprot id: A0A0F7FUH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

408015:SXIM RS01350
gene id: 408015:SXIM_RS01350
uniprot id: A0A0F7CMS2
names: Similarity
messages: Belongs to the aldose epimerase family.

408015:SXIM RS07990
gene id: 408015:SXIM_RS07990
uniprot id: A0A0F7FSI1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

408015:SXIM RS09245
gene id: 408015:SXIM_RS09245
uniprot id: A0A0F7FT94
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS20515
gene id: 408015:SXIM_RS20515
uniprot id: A0A0F7CPZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

408015:SXIM RS05935
gene id: 408015:SXIM_RS05935
uniprot id: A0A0F7FRM6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

408015:SXIM RS23415
gene id: 408015:SXIM_RS23415
uniprot id: A0A0F7G0Z7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

408015:SXIM RS07445
gene id: 408015:SXIM_RS07445
uniprot id: A0A0F7CNH0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS21040
gene id: 408015:SXIM_RS21040
uniprot id: A0A0F7FYH4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS11575
gene id: 408015:SXIM_RS11575
uniprot id: A0A0F7CNY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

408015:SXIM RS26390
gene id: 408015:SXIM_RS26390
uniprot id: A0A0F7G1N9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS24315
gene id: 408015:SXIM_RS24315
uniprot id: A0A0F7FZL4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS13180
gene id: 408015:SXIM_RS13180
uniprot id: A0A0F7CP50
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

408015:SXIM RS22975
gene id: 408015:SXIM_RS22975
uniprot id: A0A0F7CQ97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

408015:SXIM RS12630
gene id: 408015:SXIM_RS12630
uniprot id: A0A0F7FUD3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

408015:SXIM RS10215
gene id: 408015:SXIM_RS10215
uniprot id: A0A0F7FTR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

408015:SXIM RS01705
gene id: 408015:SXIM_RS01705
uniprot id: A0A0F7CMT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

408015:SXIM RS22405
gene id: 408015:SXIM_RS22405
uniprot id: A0A0F7G012
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

408015:SXIM RS24755
gene id: 408015:SXIM_RS24755
uniprot id: A0A0F7G121
names: Similarity
messages: Belongs to the peptidase S1 family.

408015:SXIM RS25605
gene id: 408015:SXIM_RS25605
uniprot id: A0A0F7G036
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

408015:SXIM RS20480
gene id: 408015:SXIM_RS20480
uniprot id: A0A0F7FZG2
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS18755
gene id: 408015:SXIM_RS18755
uniprot id: A0A0F7FXK0
names: Similarity
messages: Belongs to the peptidase S16 family.

408015:SXIM RS26875
gene id: 408015:SXIM_RS26875
uniprot id: A0A0F7G2H8
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

408015:SXIM RS16020
gene id: 408015:SXIM_RS16020
uniprot id: A0A0F7FXC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS20455
gene id: 408015:SXIM_RS20455
uniprot id: A0A0F7FXS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

408015:SXIM RS16895
gene id: 408015:SXIM_RS16895
uniprot id: A0A0F7FWP7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

408015:SXIM RS02655
gene id: 408015:SXIM_RS02655
uniprot id: A0A0F7FPQ8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

408015:SXIM RS10230
gene id: 408015:SXIM_RS10230
uniprot id: A0A0F7FUJ9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

408015:SXIM RS10640
gene id: 408015:SXIM_RS10640
uniprot id: A0A0F7FTH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS05170
gene id: 408015:SXIM_RS05170
uniprot id: A0A0F7FQZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

408015:SXIM RS08540
gene id: 408015:SXIM_RS08540
uniprot id: A0A0F7FSI5
names: Similarity
messages: Belongs to the citrate synthase family.

408015:SXIM RS20500
gene id: 408015:SXIM_RS20500
uniprot id: A0A0F7FY88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

408015:SXIM RS01470
gene id: 408015:SXIM_RS01470
uniprot id: A0A0F7CMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

408015:SXIM RS03615
gene id: 408015:SXIM_RS03615
uniprot id: A0A0F7FQI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

408015:SXIM RS07655
gene id: 408015:SXIM_RS07655
uniprot id: A0A0F7CNH9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS09535
gene id: 408015:SXIM_RS09535
uniprot id: A0A0F7CNQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

408015:SXIM RS25150
gene id: 408015:SXIM_RS25150
uniprot id: A0A0F7G166
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS21445
gene id: 408015:SXIM_RS21445
uniprot id: A0A0F7G015
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

408015:SXIM RS03175
gene id: 408015:SXIM_RS03175
uniprot id: A0A0F7FRA7
names: Similarity
messages: Belongs to the YciI family.

408015:SXIM RS15305
gene id: 408015:SXIM_RS15305
uniprot id: A0A0F7FWS6
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

408015:SXIM RS22595
gene id: 408015:SXIM_RS22595
uniprot id: A0A0F7CQ81
names: Similarity
messages: Belongs to the Nudix hydrolase family.

408015:SXIM RS02770
gene id: 408015:SXIM_RS02770
uniprot id: A0A0F7CMX9
names: Similarity
messages: Belongs to the asp23 family.

408015:SXIM RS18545
gene id: 408015:SXIM_RS18545
uniprot id: A0A0F7FXG8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

408015:SXIM RS03990
gene id: 408015:SXIM_RS03990
uniprot id: A0A0F7FQP3
names: Similarity
messages: Belongs to the peptidase U62 family.

408015:SXIM RS24650
gene id: 408015:SXIM_RS24650
uniprot id: A0A0F7CQG3
names: Similarity
messages: Belongs to the citrate synthase family.

408015:SXIM RS09655
gene id: 408015:SXIM_RS09655
uniprot id: A0A0F7FTF9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

408015:SXIM RS23525
gene id: 408015:SXIM_RS23525
uniprot id: A0A0F7CQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

408015:SXIM RS23260
gene id: 408015:SXIM_RS23260
uniprot id: A0A0F7G0X8
names: Similarity
messages: Belongs to the CdaR family.

408015:SXIM RS19260
gene id: 408015:SXIM_RS19260
uniprot id: A0A0F7FYK5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

408015:SXIM RS17155
gene id: 408015:SXIM_RS17155
uniprot id: A0A0F7CPK9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

408015:SXIM RS06685
gene id: 408015:SXIM_RS06685
uniprot id: A0A0F7FSX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

408015:SXIM RS00590
gene id: 408015:SXIM_RS00590
uniprot id: A0A0F7FQ09
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

408015:SXIM RS05770
gene id: 408015:SXIM_RS05770
uniprot id: A0A0F7FSL2
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

408015:SXIM RS07305
gene id: 408015:SXIM_RS07305
uniprot id: A0A0F7FRX5
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS09680
gene id: 408015:SXIM_RS09680
uniprot id: A0A0F7FU82
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

408015:SXIM RS05325
gene id: 408015:SXIM_RS05325
uniprot id: A0A0F7FR11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

408015:SXIM RS14285
gene id: 408015:SXIM_RS14285
uniprot id: A0A0F7FWA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS23195
gene id: 408015:SXIM_RS23195
uniprot id: A0A0F7G0X1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

408015:SXIM RS11390
gene id: 408015:SXIM_RS11390
uniprot id: A0A0F7FV26
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

408015:SXIM RS12200
gene id: 408015:SXIM_RS12200
uniprot id: A0A0F7CP11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS07795
gene id: 408015:SXIM_RS07795
uniprot id: A0A0F7FS73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS05775
gene id: 408015:SXIM_RS05775
uniprot id: A0A0F7FRJ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS19920
gene id: 408015:SXIM_RS19920
uniprot id: A0A0F7FY21
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

408015:SXIM RS07465
gene id: 408015:SXIM_RS07465
uniprot id: A0A0F7FT96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

408015:SXIM RS01750
gene id: 408015:SXIM_RS01750
uniprot id: A0A0F7FQJ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

408015:SXIM RS22140
gene id: 408015:SXIM_RS22140
uniprot id: A0A0F7G0B8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

408015:SXIM RS03055
gene id: 408015:SXIM_RS03055
uniprot id: A0A0F7FQ86
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

408015:SXIM RS20560
gene id: 408015:SXIM_RS20560
uniprot id: A0A0F7FY97
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

408015:SXIM RS15535
gene id: 408015:SXIM_RS15535
uniprot id: A0A0F7FVN0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

408015:SXIM RS02135
gene id: 408015:SXIM_RS02135
uniprot id: A0A0F7FP90
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

408015:SXIM RS12560
gene id: 408015:SXIM_RS12560
uniprot id: A0A0F7FUW1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

408015:SXIM RS23905
gene id: 408015:SXIM_RS23905
uniprot id: A0A0F7FZS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS13930
gene id: 408015:SXIM_RS13930
uniprot id: A0A0F7FW86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

408015:SXIM RS02925
gene id: 408015:SXIM_RS02925
uniprot id: A0A0F7FR76
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

408015:SXIM RS14400
gene id: 408015:SXIM_RS14400
uniprot id: A0A0F7FUU8
names: Similarity
messages: Belongs to the GARS family.

408015:SXIM RS03135
gene id: 408015:SXIM_RS03135
uniprot id: A0A0F7FPR4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

408015:SXIM RS04775
gene id: 408015:SXIM_RS04775
uniprot id: A0A0F7FQG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

408015:SXIM RS20690
gene id: 408015:SXIM_RS20690
uniprot id: A0A0F7FZJ6
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04575
gene id: 408015:SXIM_RS04575
uniprot id: A0A0F7FQQ1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

408015:SXIM RS13160
gene id: 408015:SXIM_RS13160
uniprot id: A0A0F7FV42
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

408015:SXIM RS08155
gene id: 408015:SXIM_RS08155
uniprot id: A0A0F7FTL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

408015:SXIM RS11860
gene id: 408015:SXIM_RS11860
uniprot id: A0A0F7FTY1
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS03685
gene id: 408015:SXIM_RS03685
uniprot id: A0A0F7FPZ2
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS14220
gene id: 408015:SXIM_RS14220
uniprot id: A0A0F7CP91
names: Similarity
messages: Belongs to the UPF0045 family.

408015:SXIM RS05830
gene id: 408015:SXIM_RS05830
uniprot id: A0A0F7FR08
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

408015:SXIM RS07060
gene id: 408015:SXIM_RS07060
uniprot id: A0A0F7CNF4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

408015:SXIM RS07360
gene id: 408015:SXIM_RS07360
uniprot id: A0A0F7FS86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

408015:SXIM RS25670
gene id: 408015:SXIM_RS25670
uniprot id: A0A0F7G1D6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

408015:SXIM RS01465
gene id: 408015:SXIM_RS01465
uniprot id: A0A0F7FP89
names: Similarity
messages: Belongs to the UPF0749 family.

408015:SXIM RS20155
gene id: 408015:SXIM_RS20155
uniprot id: A0A0F7FXM4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

408015:SXIM RS14480
gene id: 408015:SXIM_RS14480
uniprot id: A0A0F7FVL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

408015:SXIM RS10375
gene id: 408015:SXIM_RS10375
uniprot id: A0A0F7FTT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

408015:SXIM RS25745
gene id: 408015:SXIM_RS25745
uniprot id: A0A0F7G096
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

408015:SXIM RS12520
gene id: 408015:SXIM_RS12520
uniprot id: A0A0F7FVJ8
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10930
gene id: 408015:SXIM_RS10930
uniprot id: A0A0F7FT99
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10180
gene id: 408015:SXIM_RS10180
uniprot id: A0A0F7FUG8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

408015:SXIM RS04105
gene id: 408015:SXIM_RS04105
uniprot id: A0A0F7CN34
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

408015:SXIM RS20090
gene id: 408015:SXIM_RS20090
uniprot id: A0A0F7FYY8
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS06735
gene id: 408015:SXIM_RS06735
uniprot id: A0A0F7FRZ4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

408015:SXIM RS08095
gene id: 408015:SXIM_RS08095
uniprot id: A0A0F7CNJ7
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS22915
gene id: 408015:SXIM_RS22915
uniprot id: A0A0F7G0T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

408015:SXIM RS09300
gene id: 408015:SXIM_RS09300
uniprot id: A0A0F7FTA3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

408015:SXIM RS15735
gene id: 408015:SXIM_RS15735
uniprot id: A0A0F7FVI1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

408015:SXIM RS10260
gene id: 408015:SXIM_RS10260
uniprot id: A0A0F7FUK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

408015:SXIM RS21885
gene id: 408015:SXIM_RS21885
uniprot id: A0A0F7FYH5
names: Similarity
messages: Belongs to the UPF0102 family.

408015:SXIM RS11465
gene id: 408015:SXIM_RS11465
uniprot id: A0A0F7FU83
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS07100
gene id: 408015:SXIM_RS07100
uniprot id: A0A0F7FT43
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

408015:SXIM RS14210
gene id: 408015:SXIM_RS14210
uniprot id: A0A0F7FV05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

408015:SXIM RS17970
gene id: 408015:SXIM_RS17970
uniprot id: A0A0F7CPP2
names: Similarity
messages: Belongs to the DSD1 family.

408015:SXIM RS22065
gene id: 408015:SXIM_RS22065
uniprot id: A0A0F7FZ23
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS25400
gene id: 408015:SXIM_RS25400
uniprot id: A0A0F7G0J2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

408015:SXIM RS01665
gene id: 408015:SXIM_RS01665
uniprot id: A0A0F7FPJ6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS03630
gene id: 408015:SXIM_RS03630
uniprot id: A0A0F7CN15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

408015:SXIM RS23690
gene id: 408015:SXIM_RS23690
uniprot id: A0A0F7G131
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

408015:SXIM RS03070
gene id: 408015:SXIM_RS03070
uniprot id: A0A0F7CMZ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

408015:SXIM RS12690
gene id: 408015:SXIM_RS12690
uniprot id: A0A0F7FUE1
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS10025
gene id: 408015:SXIM_RS10025
uniprot id: A0A0F7FTL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

408015:SXIM RS06755
gene id: 408015:SXIM_RS06755
uniprot id: A0A0F7FRC0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

408015:SXIM RS20820
gene id: 408015:SXIM_RS20820
uniprot id: A0A0F7CQ09
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

408015:SXIM RS06820
gene id: 408015:SXIM_RS06820
uniprot id: A0A0F7FSY2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

408015:SXIM RS22670
gene id: 408015:SXIM_RS22670
uniprot id: A0A0F7FZA8
names: Similarity
messages: Belongs to the thymidine kinase family.

408015:SXIM RS10795
gene id: 408015:SXIM_RS10795
uniprot id: A0A0F7FTJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

408015:SXIM RS26425
gene id: 408015:SXIM_RS26425
uniprot id: A0A0F7G1P0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

408015:SXIM RS18255
gene id: 408015:SXIM_RS18255
uniprot id: A0A0F7FWT4
names: Similarity
messages: Belongs to the cytochrome P450 family.

408015:SXIM RS24570
gene id: 408015:SXIM_RS24570
uniprot id: A0A0F7FZS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

408015:SXIM RS09940
gene id: 408015:SXIM_RS09940
uniprot id: A0A0F7CNS2
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

408015:SXIM RS09970
gene id: 408015:SXIM_RS09970
uniprot id: A0A0F7FT66
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS17560
gene id: 408015:SXIM_RS17560
uniprot id: A0A0F7FY17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS08695
gene id: 408015:SXIM_RS08695
uniprot id: A0A0F7FS64
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

408015:SXIM RS19750
gene id: 408015:SXIM_RS19750
uniprot id: A0A0F7FZ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS12775
gene id: 408015:SXIM_RS12775
uniprot id: A0A0F7FU47
names: Similarity
messages: Belongs to the protease inhibitor I16 (SSI) family.

408015:SXIM RS09420
gene id: 408015:SXIM_RS09420
uniprot id: A0A0F7FU39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

408015:SXIM RS08020
gene id: 408015:SXIM_RS08020
uniprot id: A0A0F7CNJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

408015:SXIM RS28350
gene id: 408015:SXIM_RS28350
uniprot id: A0A0F7FZJ8
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

408015:SXIM RS23345
gene id: 408015:SXIM_RS23345
uniprot id: A0A0F7FZ49
names: Subunit
messages: Homotetramer.

408015:SXIM RS22270
gene id: 408015:SXIM_RS22270
uniprot id: A0A0F7FZ52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

408015:SXIM RS06440
gene id: 408015:SXIM_RS06440
uniprot id: A0A0F7FSW4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

408015:SXIM RS07550
gene id: 408015:SXIM_RS07550
uniprot id: A0A0F7FS34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

408015:SXIM RS12375
gene id: 408015:SXIM_RS12375
uniprot id: A0A0F7CP18
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

408015:SXIM RS10990
gene id: 408015:SXIM_RS10990
uniprot id: A0A0F7FTA9
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

408015:SXIM RS25200
gene id: 408015:SXIM_RS25200
uniprot id: A0A0F7G1V6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

408015:SXIM RS00740
gene id: 408015:SXIM_RS00740
uniprot id: A0A0F7FQ87
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

408015:SXIM RS25040
gene id: 408015:SXIM_RS25040
uniprot id: A0A0F7FZX1
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

408015:SXIM RS15785
gene id: 408015:SXIM_RS15785
uniprot id: A0A0F7FVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

408015:SXIM RS03445
gene id: 408015:SXIM_RS03445
uniprot id: A0A0F7CN07
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

408015:SXIM RS01245
gene id: 408015:SXIM_RS01245
uniprot id: A0A0F7FPD2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

408015:SXIM RS24995
gene id: 408015:SXIM_RS24995
uniprot id: A0A0F7G144
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

408015:SXIM RS20445
gene id: 408015:SXIM_RS20445
uniprot id: A0A0F7FXU4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS10345
gene id: 408015:SXIM_RS10345
uniprot id: A0A0F7CNT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

408015:SXIM RS15415
gene id: 408015:SXIM_RS15415
uniprot id: A0A0F7FVL0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

408015:SXIM RS22580
gene id: 408015:SXIM_RS22580
uniprot id: A0A0F7FZ95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

408015:SXIM RS11345
gene id: 408015:SXIM_RS11345
uniprot id: A0A0F7FU62
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

408015:SXIM RS08620
gene id: 408015:SXIM_RS08620
uniprot id: A0A0F7FS52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

408015:SXIM RS02320
gene id: 408015:SXIM_RS02320
uniprot id: A0A0F7CMW1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

408015:SXIM RS05445
gene id: 408015:SXIM_RS05445
uniprot id: A0A0F7FR27
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

408015:SXIM RS16485
gene id: 408015:SXIM_RS16485
uniprot id: A0A0F7FVV4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

408015:SXIM RS22935
gene id: 408015:SXIM_RS22935
uniprot id: A0A0F7FZF1
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

408015:SXIM RS03290
gene id: 408015:SXIM_RS03290
uniprot id: A0A0F7CN00
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

408015:SXIM RS26050
gene id: 408015:SXIM_RS26050
uniprot id: A0A0F7G0A7
names: Similarity
messages: Belongs to the thioesterase family.

408015:SXIM RS18170
gene id: 408015:SXIM_RS18170
uniprot id: A0A0F7FY35
names: Similarity
messages: Belongs to the FBPase class 2 family.

408015:SXIM RS21310
gene id: 408015:SXIM_RS21310
uniprot id: A0A0F7CQ29
names: Similarity
messages: Belongs to the AHA1 family.

408015:SXIM RS15495
gene id: 408015:SXIM_RS15495
uniprot id: A0A0F7FW72
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04380
gene id: 408015:SXIM_RS04380
uniprot id: A0A0F7FQV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

408015:SXIM RS13000
gene id: 408015:SXIM_RS13000
uniprot id: A0A0F7FVR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

408015:SXIM RS09365
gene id: 408015:SXIM_RS09365
uniprot id: A0A0F7FTB3
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

408015:SXIM RS10275
gene id: 408015:SXIM_RS10275
uniprot id: A0A0F7FUI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

408015:SXIM RS09880
gene id: 408015:SXIM_RS09880
uniprot id: A0A0F7FUF4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

408015:SXIM RS15125
gene id: 408015:SXIM_RS15125
uniprot id: A0A0F7FWQ5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

408015:SXIM RS08160
gene id: 408015:SXIM_RS08160
uniprot id: A0A0F7FRY8
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

408015:SXIM RS06425
gene id: 408015:SXIM_RS06425
uniprot id: A0A0F7CNC9
names: Similarity
messages: Belongs to the pirin family.

408015:SXIM RS02430
gene id: 408015:SXIM_RS02430
uniprot id: A0A0F7FPM5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

408015:SXIM RS10250
gene id: 408015:SXIM_RS10250
uniprot id: A0A0F7FTS1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

408015:SXIM RS26330
gene id: 408015:SXIM_RS26330
uniprot id: A0A0F7G0Y5
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS24715
gene id: 408015:SXIM_RS24715
uniprot id: A0A0F7FZS8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

408015:SXIM RS10380
gene id: 408015:SXIM_RS10380
uniprot id: A0A0F7FTD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

408015:SXIM RS08615
gene id: 408015:SXIM_RS08615
uniprot id: A0A0F7FTT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

408015:SXIM RS17370
gene id: 408015:SXIM_RS17370
uniprot id: A0A0F7FWU7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

408015:SXIM RS14775
gene id: 408015:SXIM_RS14775
uniprot id: A0A0F7FV89
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

408015:SXIM RS19935
gene id: 408015:SXIM_RS19935
uniprot id: A0A0F7FZ70
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

408015:SXIM RS20890
gene id: 408015:SXIM_RS20890
uniprot id: A0A0F7FY18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

408015:SXIM RS21485
gene id: 408015:SXIM_RS21485
uniprot id: A0A0F7FYC8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

408015:SXIM RS03045
gene id: 408015:SXIM_RS03045
uniprot id: A0A0F7CMZ0
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS02265
gene id: 408015:SXIM_RS02265
uniprot id: A0A0F7FQS6
names: Similarity
messages: Belongs to the glutamine synthetase family.

408015:SXIM RS09565
gene id: 408015:SXIM_RS09565
uniprot id: A0A0F7FU64
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

408015:SXIM RS01905
gene id: 408015:SXIM_RS01905
uniprot id: A0A0F7FP54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

408015:SXIM RS05125
gene id: 408015:SXIM_RS05125
uniprot id: A0A0F7FS92
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS10910
gene id: 408015:SXIM_RS10910
uniprot id: A0A0F7FTZ8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

408015:SXIM RS13215
gene id: 408015:SXIM_RS13215
uniprot id: A0A0F7FV52
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS22445
gene id: 408015:SXIM_RS22445
uniprot id: A0A0F7FYQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS07645
gene id: 408015:SXIM_RS07645
uniprot id: A0A0F7FRQ9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS01565
gene id: 408015:SXIM_RS01565
uniprot id: A0A0F7FQL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

408015:SXIM RS16285
gene id: 408015:SXIM_RS16285
uniprot id: A0A0F7CPH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

408015:SXIM RS07325
gene id: 408015:SXIM_RS07325
uniprot id: A0A0F7FT60
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

408015:SXIM RS21890
gene id: 408015:SXIM_RS21890
uniprot id: A0A0F7CQ52
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

408015:SXIM RS17575
gene id: 408015:SXIM_RS17575
uniprot id: A0A0F7FXT1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

408015:SXIM RS15220
gene id: 408015:SXIM_RS15220
uniprot id: A0A0F7FVH8
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS25160
gene id: 408015:SXIM_RS25160
uniprot id: A0A0F7G0G1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

408015:SXIM RS22995
gene id: 408015:SXIM_RS22995
uniprot id: A0A0F7FZF9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

408015:SXIM RS25350
gene id: 408015:SXIM_RS25350
uniprot id: A0A0F7G1X7
names: Cofactor
messages: Can also use Mn(2+) ion.

408015:SXIM RS14790
gene id: 408015:SXIM_RS14790
uniprot id: A0A0F7FV17
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

408015:SXIM RS04570
gene id: 408015:SXIM_RS04570
uniprot id: A0A0F7CN53
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

408015:SXIM RS02725
gene id: 408015:SXIM_RS02725
uniprot id: A0A0F7FR69
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS20810
gene id: 408015:SXIM_RS20810
uniprot id: A0A0F7FXZ3
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

408015:SXIM RS24605
gene id: 408015:SXIM_RS24605
uniprot id: A0A0F7FZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

408015:SXIM RS04155
gene id: 408015:SXIM_RS04155
uniprot id: A0A0F7CN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS24210
gene id: 408015:SXIM_RS24210
uniprot id: A0A0F7FZI5
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

408015:SXIM RS18185
gene id: 408015:SXIM_RS18185
uniprot id: A0A0F7FY98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

408015:SXIM RS20150
gene id: 408015:SXIM_RS20150
uniprot id: A0A0F7CPY1
names: Similarity
messages: Belongs to the XFP family.

408015:SXIM RS23505
gene id: 408015:SXIM_RS23505
uniprot id: A0A0F7FZ76
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

408015:SXIM RS01630
gene id: 408015:SXIM_RS01630
uniprot id: A0A0F7CMT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

408015:SXIM RS08535
gene id: 408015:SXIM_RS08535
uniprot id: A0A0F7FSP8
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS22740
gene id: 408015:SXIM_RS22740
uniprot id: A0A0F7CQ87
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS05525
gene id: 408015:SXIM_RS05525
uniprot id: A0A0F7FSF2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

408015:SXIM RS21065
gene id: 408015:SXIM_RS21065
uniprot id: A0A0F7FZG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

408015:SXIM RS08585
gene id: 408015:SXIM_RS08585
uniprot id: A0A0F7FTR3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

408015:SXIM RS09630
gene id: 408015:SXIM_RS09630
uniprot id: A0A0F7FT13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

408015:SXIM RS20065
gene id: 408015:SXIM_RS20065
uniprot id: A0A0F7FY43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

408015:SXIM RS14965
gene id: 408015:SXIM_RS14965
uniprot id: A0A0F7FWS4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS13300
gene id: 408015:SXIM_RS13300
uniprot id: A0A0F7FUB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

408015:SXIM RS17445
gene id: 408015:SXIM_RS17445
uniprot id: A0A0F7CPM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

408015:SXIM RS07870
gene id: 408015:SXIM_RS07870
uniprot id: A0A0F7FSF8
names: Similarity
messages: Belongs to the peptidase M1 family.

408015:SXIM RS18005
gene id: 408015:SXIM_RS18005
uniprot id: A0A0F7FY75
names: Similarity
messages: Belongs to the GSP E family.

408015:SXIM RS12020
gene id: 408015:SXIM_RS12020
uniprot id: A0A0F7CP04
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS19375
gene id: 408015:SXIM_RS19375
uniprot id: A0A0F7FYX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS14100
gene id: 408015:SXIM_RS14100
uniprot id: A0A0F7FW78
names: Subcellular Location Annotation
messages: Secreted

408015:SXIM RS20865
gene id: 408015:SXIM_RS20865
uniprot id: A0A0F7FZL6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

408015:SXIM RS07685
gene id: 408015:SXIM_RS07685
uniprot id: A0A0F7FTC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

408015:SXIM RS05010
gene id: 408015:SXIM_RS05010
uniprot id: A0A0F7FQX6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

408015:SXIM RS23175
gene id: 408015:SXIM_RS23175
uniprot id: A0A0F7CQA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

408015:SXIM RS11295
gene id: 408015:SXIM_RS11295
uniprot id: A0A0F7FV10
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

408015:SXIM RS02165
gene id: 408015:SXIM_RS02165
uniprot id: A0A0F7FP94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

408015:SXIM RS11500
gene id: 408015:SXIM_RS11500
uniprot id: A0A0F7CNY3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

408015:SXIM RS18640
gene id: 408015:SXIM_RS18640
uniprot id: A0A0F7FXI2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

408015:SXIM RS21950
gene id: 408015:SXIM_RS21950
uniprot id: A0A0F7FYI4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

408015:SXIM RS14085
gene id: 408015:SXIM_RS14085
uniprot id: A0A0F7CP86
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS07335
gene id: 408015:SXIM_RS07335
uniprot id: A0A0F7FRX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

408015:SXIM RS21260
gene id: 408015:SXIM_RS21260
uniprot id: A0A0F7CQ27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS11470
gene id: 408015:SXIM_RS11470
uniprot id: A0A0F7FTT5
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS21370
gene id: 408015:SXIM_RS21370
uniprot id: A0A0F7FZN1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

408015:SXIM RS22320
gene id: 408015:SXIM_RS22320
uniprot id: A0A0F7FZ56
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.

408015:SXIM RS01560
gene id: 408015:SXIM_RS01560
uniprot id: A0A0F7FPA1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

408015:SXIM RS05005
gene id: 408015:SXIM_RS05005
uniprot id: A0A0F7FR35
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

408015:SXIM RS15780
gene id: 408015:SXIM_RS15780
uniprot id: A0A0F7FWB4
names: Similarity
messages: Belongs to the PstS family.

408015:SXIM RS03900
gene id: 408015:SXIM_RS03900
uniprot id: A0A0F7FQM5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

408015:SXIM RS10810
gene id: 408015:SXIM_RS10810
uniprot id: A0A0F7FT77
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

408015:SXIM RS09150
gene id: 408015:SXIM_RS09150
uniprot id: A0A0F7CNN9
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS24675
gene id: 408015:SXIM_RS24675
uniprot id: A0A0F7CQG4
names: Similarity
messages: Belongs to the peptidase S8 family.

408015:SXIM RS01810
gene id: 408015:SXIM_RS01810
uniprot id: A0A0F7FP38
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

408015:SXIM RS20645
gene id: 408015:SXIM_RS20645
uniprot id: A0A0F7FZ88
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

408015:SXIM RS10200
gene id: 408015:SXIM_RS10200
uniprot id: A0A0F7FUJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

408015:SXIM RS05070
gene id: 408015:SXIM_RS05070
uniprot id: A0A0F7FR43
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

408015:SXIM RS19320
gene id: 408015:SXIM_RS19320
uniprot id: A0A0F7FX87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

408015:SXIM RS06225
gene id: 408015:SXIM_RS06225
uniprot id: A0A0F7FST2
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04890
gene id: 408015:SXIM_RS04890
uniprot id: A0A0F7FR20
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

408015:SXIM RS25025
gene id: 408015:SXIM_RS25025
uniprot id: A0A0F7G149
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

408015:SXIM RS08255
gene id: 408015:SXIM_RS08255
uniprot id: A0A0F7FTL4
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS21480
gene id: 408015:SXIM_RS21480
uniprot id: A0A0F7CQ36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

408015:SXIM RS01815
gene id: 408015:SXIM_RS01815
uniprot id: A0A0F7FQK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

408015:SXIM RS07330
gene id: 408015:SXIM_RS07330
uniprot id: A0A0F7FS82
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

408015:SXIM RS01180
gene id: 408015:SXIM_RS01180
uniprot id: A0A0F7FQ99
names: Similarity
messages: Belongs to the pirin family.

408015:SXIM RS06960
gene id: 408015:SXIM_RS06960
uniprot id: A0A0F7FRF3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

408015:SXIM RS07495
gene id: 408015:SXIM_RS07495
uniprot id: A0A0F7FTA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

408015:SXIM RS10225
gene id: 408015:SXIM_RS10225
uniprot id: A0A0F7FTA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

408015:SXIM RS09540
gene id: 408015:SXIM_RS09540
uniprot id: A0A0F7FU58
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

408015:SXIM RS22630
gene id: 408015:SXIM_RS22630
uniprot id: A0A0F7G046
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

408015:SXIM RS21050
gene id: 408015:SXIM_RS21050
uniprot id: A0A0F7FY40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

408015:SXIM RS09860
gene id: 408015:SXIM_RS09860
uniprot id: A0A0F7FSR7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

408015:SXIM RS10780
gene id: 408015:SXIM_RS10780
uniprot id: A0A0F7CNV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

408015:SXIM RS05015
gene id: 408015:SXIM_RS05015
uniprot id: A0A0F7CN72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

408015:SXIM RS19600
gene id: 408015:SXIM_RS19600
uniprot id: A0A0F7FZ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS01985
gene id: 408015:SXIM_RS01985
uniprot id: A0A0F7FQT3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

408015:SXIM RS03730
gene id: 408015:SXIM_RS03730
uniprot id: A0A0F7FQK3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

408015:SXIM RS05435
gene id: 408015:SXIM_RS05435
uniprot id: A0A0F7CN89
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

408015:SXIM RS13585
gene id: 408015:SXIM_RS13585
uniprot id: A0A0F7FV96
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

408015:SXIM RS10475
gene id: 408015:SXIM_RS10475
uniprot id: A0A0F7CNU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

408015:SXIM RS18870
gene id: 408015:SXIM_RS18870
uniprot id: A0A0F7FYE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

408015:SXIM RS10145
gene id: 408015:SXIM_RS10145
uniprot id: A0A0F7CNT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

408015:SXIM RS01830
gene id: 408015:SXIM_RS01830
uniprot id: A0A0F7CMU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

408015:SXIM RS18840
gene id: 408015:SXIM_RS18840
uniprot id: A0A0F7FYE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

408015:SXIM RS09775
gene id: 408015:SXIM_RS09775
uniprot id: A0A0F7FU97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

408015:SXIM RS05300
gene id: 408015:SXIM_RS05300
uniprot id: A0A0F7FSB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

408015:SXIM RS27015
gene id: 408015:SXIM_RS27015
uniprot id: A0A0F7G2J4
names: Similarity
messages: Belongs to the FemABX family.

408015:SXIM RS09055
gene id: 408015:SXIM_RS09055
uniprot id: A0A0F7FT68
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

408015:SXIM RS15775
gene id: 408015:SXIM_RS15775
uniprot id: A0A0F7CPF4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

408015:SXIM RS22050
gene id: 408015:SXIM_RS22050
uniprot id: A0A0F7FYL4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

408015:SXIM RS19860
gene id: 408015:SXIM_RS19860
uniprot id: A0A0F7FY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS21815
gene id: 408015:SXIM_RS21815
uniprot id: A0A0F7FYY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

408015:SXIM RS11590
gene id: 408015:SXIM_RS11590
uniprot id: A0A0F7FUA4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

408015:SXIM RS21945
gene id: 408015:SXIM_RS21945
uniprot id: A0A0F7FZ06
names: Similarity
messages: Belongs to the ABC transporter superfamily.

408015:SXIM RS21875
gene id: 408015:SXIM_RS21875
uniprot id: A0A0F7FZU3
names: Similarity
messages: Belongs to the DprA/Smf family.

408015:SXIM RS26665
gene id: 408015:SXIM_RS26665
uniprot id: A0A0F7G2F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS04645
gene id: 408015:SXIM_RS04645
uniprot id: A0A0F7CN56
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

408015:SXIM RS18510
gene id: 408015:SXIM_RS18510
uniprot id: A0A0F7CPR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

408015:SXIM RS21830
gene id: 408015:SXIM_RS21830
uniprot id: A0A0F7FYI3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

408015:SXIM RS10185
gene id: 408015:SXIM_RS10185
uniprot id: A0A0F7FTR2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

408015:SXIM RS04150
gene id: 408015:SXIM_RS04150
uniprot id: A0A0F7FRS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS13715
gene id: 408015:SXIM_RS13715
uniprot id: A0A0F7FVB0
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS21045
gene id: 408015:SXIM_RS21045
uniprot id: A0A0F7CQ18
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS04125
gene id: 408015:SXIM_RS04125
uniprot id: A0A0F7FQ55
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

408015:SXIM RS15225
gene id: 408015:SXIM_RS15225
uniprot id: A0A0F7FX06
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

408015:SXIM RS06050
gene id: 408015:SXIM_RS06050
uniprot id: A0A0F7FSP5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

408015:SXIM RS16580
gene id: 408015:SXIM_RS16580
uniprot id: A0A0F7FW38
names: Subcellular Location Annotation
messages: Membrane

408015:SXIM RS25735
gene id: 408015:SXIM_RS25735
uniprot id: A0A0F7G0N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

408015:SXIM RS02085
gene id: 408015:SXIM_RS02085
uniprot id: A0A0F7FQP6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

408015:SXIM RS24490
gene id: 408015:SXIM_RS24490
uniprot id: A0A0F7G064
names: Subcellular Location Annotation
messages: Secreted

408015:SXIM RS10220
gene id: 408015:SXIM_RS10220
uniprot id: A0A0F7CNT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

408015:SXIM RS19380
gene id: 408015:SXIM_RS19380
uniprot id: A0A0F7FX95
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

408015:SXIM RS07180
gene id: 408015:SXIM_RS07180
uniprot id: A0A0F7CNF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

408015:SXIM RS03815
gene id: 408015:SXIM_RS03815
uniprot id: A0A0F7FRK5
names: Similarity
messages: Belongs to the TlyA family.

408015:SXIM RS19775
gene id: 408015:SXIM_RS19775
uniprot id: A0A0F7FZ42
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

408015:SXIM RS21130
gene id: 408015:SXIM_RS21130
uniprot id: A0A0F7FYJ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

408015:SXIM RS08480
gene id: 408015:SXIM_RS08480
uniprot id: A0A0F7FSH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

408015:SXIM RS03960
gene id: 408015:SXIM_RS03960
uniprot id: A0A0F7CN28
names: Subcellular Location Annotation
messages: Membrane