396588:TGR7 RS09315
gene id: 396588:TGR7_RS09315
uniprot id: B8GSN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS00435
gene id: 396588:TGR7_RS00435
uniprot id: B8GTD2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

396588:TGR7 RS09915
gene id: 396588:TGR7_RS09915
uniprot id: B8GT45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

396588:TGR7 RS08810
gene id: 396588:TGR7_RS08810
uniprot id: B8GSD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

396588:TGR7 RS11730
gene id: 396588:TGR7_RS11730
uniprot id: B8GV73
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

396588:TGR7 RS10110
gene id: 396588:TGR7_RS10110
uniprot id: B8GT84
names: Similarity
messages: Belongs to the YciI family.

396588:TGR7 RS06175
gene id: 396588:TGR7_RS06175
uniprot id: B8GQC5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

396588:TGR7 RS07705
gene id: 396588:TGR7_RS07705
uniprot id: B8GRR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS16385
gene id: 396588:TGR7_RS16385
uniprot id: B8GR80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS11135
gene id: 396588:TGR7_RS11135
uniprot id: B8GUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS15300
gene id: 396588:TGR7_RS15300
uniprot id: B8GPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS14495
gene id: 396588:TGR7_RS14495
uniprot id: B8GP42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

396588:TGR7 RS04580
gene id: 396588:TGR7_RS04580
uniprot id: B8GNS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

396588:TGR7 RS06060
gene id: 396588:TGR7_RS06060
uniprot id: B8GQA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

396588:TGR7 RS04840
gene id: 396588:TGR7_RS04840
uniprot id: B8GNW9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

396588:TGR7 RS09560
gene id: 396588:TGR7_RS09560
uniprot id: B8GSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

396588:TGR7 RS11690
gene id: 396588:TGR7_RS11690
uniprot id: B8GV69
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

396588:TGR7 RS06115
gene id: 396588:TGR7_RS06115
uniprot id: B8GQB3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

396588:TGR7 RS03215
gene id: 396588:TGR7_RS03215
uniprot id: B8GLZ0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

396588:TGR7 RS04850
gene id: 396588:TGR7_RS04850
uniprot id: B8GNX1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

396588:TGR7 RS03610
gene id: 396588:TGR7_RS03610
uniprot id: B8GMJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

396588:TGR7 RS11140
gene id: 396588:TGR7_RS11140
uniprot id: B8GUI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

396588:TGR7 RS10045
gene id: 396588:TGR7_RS10045
uniprot id: B8GT71
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

396588:TGR7 RS10065
gene id: 396588:TGR7_RS10065
uniprot id: B8GT75
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

396588:TGR7 RS09865
gene id: 396588:TGR7_RS09865
uniprot id: B8GT33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

396588:TGR7 RS11695
gene id: 396588:TGR7_RS11695
uniprot id: B8GV70
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

396588:TGR7 RS16635
gene id: 396588:TGR7_RS16635
uniprot id: B8GRD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS04760
gene id: 396588:TGR7_RS04760
uniprot id: B8GNV2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

396588:TGR7 RS16245
gene id: 396588:TGR7_RS16245
uniprot id: B8GQT1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS05950
gene id: 396588:TGR7_RS05950
uniprot id: B8GQ80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

396588:TGR7 RS06440
gene id: 396588:TGR7_RS06440
uniprot id: B8GQV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

396588:TGR7 RS04190
gene id: 396588:TGR7_RS04190
uniprot id: B8GN78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

396588:TGR7 RS03880
gene id: 396588:TGR7_RS03880
uniprot id: B8GMP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

396588:TGR7 RS09855
gene id: 396588:TGR7_RS09855
uniprot id: B8GT31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS00870
gene id: 396588:TGR7_RS00870
uniprot id: B8GTZ1
names: Similarity
messages: Belongs to the UPF0229 family.

396588:TGR7 RS00955
gene id: 396588:TGR7_RS00955
uniprot id: B8GU09
names: Similarity
messages: Belongs to the DprA/Smf family.

396588:TGR7 RS09705
gene id: 396588:TGR7_RS09705
uniprot id: B8GT01
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

396588:TGR7 RS08480
gene id: 396588:TGR7_RS08480
uniprot id: B8GS70
names: Similarity
messages: Belongs to the CapA family.

396588:TGR7 RS03570
gene id: 396588:TGR7_RS03570
uniprot id: B8GMI2
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

396588:TGR7 RS15205
gene id: 396588:TGR7_RS15205
uniprot id: B8GPV6
names: Similarity
messages: Belongs to the glutamate synthase family.

396588:TGR7 RS05985
gene id: 396588:TGR7_RS05985
uniprot id: B8GQ87
names: Similarity
messages: Belongs to the UPF0234 family.

396588:TGR7 RS10570
gene id: 396588:TGR7_RS10570
uniprot id: B8GTU8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

396588:TGR7 RS06335
gene id: 396588:TGR7_RS06335
uniprot id: B8GQF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

396588:TGR7 RS04505
gene id: 396588:TGR7_RS04505
uniprot id: B8GL16
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

396588:TGR7 RS04005
gene id: 396588:TGR7_RS04005
uniprot id: B8GN41
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS09985
gene id: 396588:TGR7_RS09985
uniprot id: B8GT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

396588:TGR7 RS10220
gene id: 396588:TGR7_RS10220
uniprot id: B8GTM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

396588:TGR7 RS13430
gene id: 396588:TGR7_RS13430
uniprot id: B8GMT1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

396588:TGR7 RS14780
gene id: 396588:TGR7_RS14780
uniprot id: B8GP97
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

396588:TGR7 RS10140
gene id: 396588:TGR7_RS10140
uniprot id: B8GTL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

396588:TGR7 RS07715
gene id: 396588:TGR7_RS07715
uniprot id: B8GRR8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

396588:TGR7 RS02790
gene id: 396588:TGR7_RS02790
uniprot id: B8GLQ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

396588:TGR7 RS13320
gene id: 396588:TGR7_RS13320
uniprot id: B8GMQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

396588:TGR7 RS00480
gene id: 396588:TGR7_RS00480
uniprot id: B8GTE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

396588:TGR7 RS14530
gene id: 396588:TGR7_RS14530
uniprot id: B8GP49
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

396588:TGR7 RS03615
gene id: 396588:TGR7_RS03615
uniprot id: B8GMJ1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

396588:TGR7 RS09925
gene id: 396588:TGR7_RS09925
uniprot id: B8GT47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

396588:TGR7 RS00310
gene id: 396588:TGR7_RS00310
uniprot id: B8GTA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS10330
gene id: 396588:TGR7_RS10330
uniprot id: B8GTP9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

396588:TGR7 RS12115
gene id: 396588:TGR7_RS12115
uniprot id: B8GLD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

396588:TGR7 RS04860
gene id: 396588:TGR7_RS04860
uniprot id: B8GNX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

396588:TGR7 RS03320
gene id: 396588:TGR7_RS03320
uniprot id: B8GMD2
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

396588:TGR7 RS07560
gene id: 396588:TGR7_RS07560
uniprot id: B8GRN7
names: Similarity
messages: Belongs to the PrpD family.

396588:TGR7 RS14615
gene id: 396588:TGR7_RS14615
uniprot id: B8GP66
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

396588:TGR7 RS12980
gene id: 396588:TGR7_RS12980
uniprot id: B8GM72
names: Similarity
messages: Belongs to the UPF0178 family.

396588:TGR7 RS02505
gene id: 396588:TGR7_RS02505
uniprot id: B8GL86
names: Subcellular Location Annotation
messages: Cytoplasm

396588:TGR7 RS08180
gene id: 396588:TGR7_RS08180
uniprot id: B8GS09
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

396588:TGR7 RS14100
gene id: 396588:TGR7_RS14100
uniprot id: B8GNJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

396588:TGR7 RS15480
gene id: 396588:TGR7_RS15480
uniprot id: B8GQ07
names: Similarity
messages: Belongs to the glutamine synthetase family.

396588:TGR7 RS16455
gene id: 396588:TGR7_RS16455
uniprot id: B8GR93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

396588:TGR7 RS12895
gene id: 396588:TGR7_RS12895
uniprot id: B8GM56
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS01410
gene id: 396588:TGR7_RS01410
uniprot id: B8GUA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

396588:TGR7 RS02445
gene id: 396588:TGR7_RS02445
uniprot id: B8GL74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

396588:TGR7 RS15965
gene id: 396588:TGR7_RS15965
uniprot id: B8GQM8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

396588:TGR7 RS06010
gene id: 396588:TGR7_RS06010
uniprot id: B8GQ92
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

396588:TGR7 RS14540
gene id: 396588:TGR7_RS14540
uniprot id: B8GP51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

396588:TGR7 RS02870
gene id: 396588:TGR7_RS02870
uniprot id: B8GLS2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS04420
gene id: 396588:TGR7_RS04420
uniprot id: B8GNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

396588:TGR7 RS07220
gene id: 396588:TGR7_RS07220
uniprot id: B8GRH1
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

396588:TGR7 RS03230
gene id: 396588:TGR7_RS03230
uniprot id: B8GLZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

396588:TGR7 RS13840
gene id: 396588:TGR7_RS13840
uniprot id: B8GN16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

396588:TGR7 RS01785
gene id: 396588:TGR7_RS01785
uniprot id: B8GUV0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

396588:TGR7 RS03860
gene id: 396588:TGR7_RS03860
uniprot id: B8GMP0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

396588:TGR7 RS14975
gene id: 396588:TGR7_RS14975
uniprot id: B8GPD5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

396588:TGR7 RS04325
gene id: 396588:TGR7_RS04325
uniprot id: B8GNA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

396588:TGR7 RS14485
gene id: 396588:TGR7_RS14485
uniprot id: B8GP40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS03080
gene id: 396588:TGR7_RS03080
uniprot id: B8GLW3
names: Similarity
messages: Belongs to the HsdR family.

396588:TGR7 RS06165
gene id: 396588:TGR7_RS06165
uniprot id: B8GQC3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

396588:TGR7 RS05380
gene id: 396588:TGR7_RS05380
uniprot id: B8GPJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

396588:TGR7 RS05910
gene id: 396588:TGR7_RS05910
uniprot id: B8GQ72
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

396588:TGR7 RS04680
gene id: 396588:TGR7_RS04680
uniprot id: B8GNT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

396588:TGR7 RS07565
gene id: 396588:TGR7_RS07565
uniprot id: B8GRN8
names: Similarity
messages: Belongs to the citrate synthase family.

396588:TGR7 RS07910
gene id: 396588:TGR7_RS07910
uniprot id: B8GRV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

396588:TGR7 RS10660
gene id: 396588:TGR7_RS10660
uniprot id: B8GTW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

396588:TGR7 RS12850
gene id: 396588:TGR7_RS12850
uniprot id: B8GM47
names: Similarity
messages: Belongs to the peptidase U62 family.

396588:TGR7 RS04280
gene id: 396588:TGR7_RS04280
uniprot id: B8GN96
names: Similarity
messages: Belongs to the universal stress protein A family.

396588:TGR7 RS06230
gene id: 396588:TGR7_RS06230
uniprot id: B8GQD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

396588:TGR7 RS05800
gene id: 396588:TGR7_RS05800
uniprot id: B8GPS8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

396588:TGR7 RS06620
gene id: 396588:TGR7_RS06620
uniprot id: B8GQY6
names: Similarity
messages: Belongs to the MotB family.

396588:TGR7 RS11635
gene id: 396588:TGR7_RS11635
uniprot id: B8GV58
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

396588:TGR7 RS11200
gene id: 396588:TGR7_RS11200
uniprot id: B8GUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

396588:TGR7 RS15420
gene id: 396588:TGR7_RS15420
uniprot id: B8GPZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

396588:TGR7 RS16365
gene id: 396588:TGR7_RS16365
uniprot id: B8GR76
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

396588:TGR7 RS08385
gene id: 396588:TGR7_RS08385
uniprot id: B8GS51
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

396588:TGR7 RS00495
gene id: 396588:TGR7_RS00495
uniprot id: B8GTE3
names: Similarity
messages: Belongs to the UPF0758 family.

396588:TGR7 RS09090
gene id: 396588:TGR7_RS09090
uniprot id: B8GSJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

396588:TGR7 RS10605
gene id: 396588:TGR7_RS10605
uniprot id: B8GTV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

396588:TGR7 RS06185
gene id: 396588:TGR7_RS06185
uniprot id: B8GQC7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

396588:TGR7 RS13215
gene id: 396588:TGR7_RS13215
uniprot id: B8GMB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

396588:TGR7 RS11375
gene id: 396588:TGR7_RS11375
uniprot id: B8GV06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

396588:TGR7 RS03650
gene id: 396588:TGR7_RS03650
uniprot id: B8GMJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

396588:TGR7 RS10995
gene id: 396588:TGR7_RS10995
uniprot id: B8GUF7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

396588:TGR7 RS04830
gene id: 396588:TGR7_RS04830
uniprot id: B8GNW7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

396588:TGR7 RS02270
gene id: 396588:TGR7_RS02270
uniprot id: B8GL40
names: Similarity
messages: Belongs to the GSP E family.

396588:TGR7 RS07920
gene id: 396588:TGR7_RS07920
uniprot id: B8GRV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

396588:TGR7 RS09870
gene id: 396588:TGR7_RS09870
uniprot id: B8GT34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

396588:TGR7 RS15930
gene id: 396588:TGR7_RS15930
uniprot id: B8GQM1
names: Similarity
messages: Belongs to the FPG family.

396588:TGR7 RS06120
gene id: 396588:TGR7_RS06120
uniprot id: B8GQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

396588:TGR7 RS14775
gene id: 396588:TGR7_RS14775
uniprot id: B8GP96
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

396588:TGR7 RS01620
gene id: 396588:TGR7_RS01620
uniprot id: B8GUR6
names: Subcellular Location Annotation
messages: Mitochondrion

396588:TGR7 RS03185
gene id: 396588:TGR7_RS03185
uniprot id: B8GLY3
names: Similarity
messages: Belongs to the UPF0047 family.

396588:TGR7 RS03670
gene id: 396588:TGR7_RS03670
uniprot id: B8GMK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

396588:TGR7 RS16000
gene id: 396588:TGR7_RS16000
uniprot id: B8GQN5
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

396588:TGR7 RS16405
gene id: 396588:TGR7_RS16405
uniprot id: B8GR84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

396588:TGR7 RS03125
gene id: 396588:TGR7_RS03125
uniprot id: B8GLX2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

396588:TGR7 RS02325
gene id: 396588:TGR7_RS02325
uniprot id: B8GL51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

396588:TGR7 RS06795
gene id: 396588:TGR7_RS06795
uniprot id: B8GR21
names: Similarity
messages: Belongs to the peptidase S49 family.

396588:TGR7 RS01795
gene id: 396588:TGR7_RS01795
uniprot id: B8GUV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

396588:TGR7 RS07775
gene id: 396588:TGR7_RS07775
uniprot id: B8GRT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

396588:TGR7 RS10485
gene id: 396588:TGR7_RS10485
uniprot id: B8GTS8
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

396588:TGR7 RS03430
gene id: 396588:TGR7_RS03430
uniprot id: B8GMF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

396588:TGR7 RS15190
gene id: 396588:TGR7_RS15190
uniprot id: B8GPV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

396588:TGR7 RS03885
gene id: 396588:TGR7_RS03885
uniprot id: B8GMP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

396588:TGR7 RS11940
gene id: 396588:TGR7_RS11940
uniprot id: B8GVB4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS14635
gene id: 396588:TGR7_RS14635
uniprot id: B8GP70
names: Similarity
messages: Belongs to the GSP E family.

396588:TGR7 RS07330
gene id: 396588:TGR7_RS07330
uniprot id: B8GRJ0
names: Similarity
messages: Belongs to the RecJ family.

396588:TGR7 RS03425
gene id: 396588:TGR7_RS03425
uniprot id: B8GMF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS12575
gene id: 396588:TGR7_RS12575
uniprot id: B8GLM4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

396588:TGR7 RS12320
gene id: 396588:TGR7_RS12320
uniprot id: B8GLH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

396588:TGR7 RS06130
gene id: 396588:TGR7_RS06130
uniprot id: B8GQB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

396588:TGR7 RS04375
gene id: 396588:TGR7_RS04375
uniprot id: B8GNB4
names: Similarity
messages: Belongs to the HSP15 family.

396588:TGR7 RS11505
gene id: 396588:TGR7_RS11505
uniprot id: B8GV31
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

396588:TGR7 RS09260
gene id: 396588:TGR7_RS09260
uniprot id: B8GSM6
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

396588:TGR7 RS04565
gene id: 396588:TGR7_RS04565
uniprot id: B8GNS0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

396588:TGR7 RS16450
gene id: 396588:TGR7_RS16450
uniprot id: B8GR92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

396588:TGR7 RS05340
gene id: 396588:TGR7_RS05340
uniprot id: B8GPI7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

396588:TGR7 RS01625
gene id: 396588:TGR7_RS01625
uniprot id: B8GUR7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

396588:TGR7 RS05005
gene id: 396588:TGR7_RS05005
uniprot id: B8GP00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

396588:TGR7 RS09190
gene id: 396588:TGR7_RS09190
uniprot id: B8GSL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

396588:TGR7 RS15970
gene id: 396588:TGR7_RS15970
uniprot id: B8GQM9
names: Similarity
messages: Belongs to the RutC family.

396588:TGR7 RS04080
gene id: 396588:TGR7_RS04080
uniprot id: B8GN56
names: Subcellular Location Annotation
messages: Cytoplasm

396588:TGR7 RS05915
gene id: 396588:TGR7_RS05915
uniprot id: B8GQ73
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

396588:TGR7 RS12695
gene id: 396588:TGR7_RS12695
uniprot id: B8GM18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

396588:TGR7 RS12445
gene id: 396588:TGR7_RS12445
uniprot id: B8GLJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

396588:TGR7 RS01805
gene id: 396588:TGR7_RS01805
uniprot id: B8GUV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

396588:TGR7 RS01360
gene id: 396588:TGR7_RS01360
uniprot id: B8GU91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

396588:TGR7 RS13610
gene id: 396588:TGR7_RS13610
uniprot id: B8GMX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

396588:TGR7 RS13580
gene id: 396588:TGR7_RS13580
uniprot id: B8GMW4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

396588:TGR7 RS05290
gene id: 396588:TGR7_RS05290
uniprot id: B8GPH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

396588:TGR7 RS05690
gene id: 396588:TGR7_RS05690
uniprot id: B8GPQ5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

396588:TGR7 RS16585
gene id: 396588:TGR7_RS16585
uniprot id: B8GRC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

396588:TGR7 RS10425
gene id: 396588:TGR7_RS10425
uniprot id: B8GTR6
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS16145
gene id: 396588:TGR7_RS16145
uniprot id: B8GQR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

396588:TGR7 RS01815
gene id: 396588:TGR7_RS01815
uniprot id: B8GUV6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

396588:TGR7 RS16460
gene id: 396588:TGR7_RS16460
uniprot id: B8GR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

396588:TGR7 RS12990
gene id: 396588:TGR7_RS12990
uniprot id: B8GM74
names: Similarity
messages: Belongs to the MipA/OmpV family.

396588:TGR7 RS02815
gene id: 396588:TGR7_RS02815
uniprot id: B8GLR1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

396588:TGR7 RS02165
gene id: 396588:TGR7_RS02165
uniprot id: B8GL18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

396588:TGR7 RS14525
gene id: 396588:TGR7_RS14525
uniprot id: B8GP48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

396588:TGR7 RS06955
gene id: 396588:TGR7_RS06955
uniprot id: B8GR52
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

396588:TGR7 RS09170
gene id: 396588:TGR7_RS09170
uniprot id: B8GSK8
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

396588:TGR7 RS02405
gene id: 396588:TGR7_RS02405
uniprot id: B8GL66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

396588:TGR7 RS13180
gene id: 396588:TGR7_RS13180
uniprot id: B8GMB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

396588:TGR7 RS12180
gene id: 396588:TGR7_RS12180
uniprot id: B8GLE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS02155
gene id: 396588:TGR7_RS02155
uniprot id: B8GL16
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

396588:TGR7 RS03465
gene id: 396588:TGR7_RS03465
uniprot id: B8GMG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

396588:TGR7 RS06605
gene id: 396588:TGR7_RS06605
uniprot id: B8GQY4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

396588:TGR7 RS00275
gene id: 396588:TGR7_RS00275
uniprot id: B8GTA0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

396588:TGR7 RS08770
gene id: 396588:TGR7_RS08770
uniprot id: B8GSC9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS01810
gene id: 396588:TGR7_RS01810
uniprot id: B8GUV5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

396588:TGR7 RS06540
gene id: 396588:TGR7_RS06540
uniprot id: B8GQX1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

396588:TGR7 RS06090
gene id: 396588:TGR7_RS06090
uniprot id: B8GQA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

396588:TGR7 RS16590
gene id: 396588:TGR7_RS16590
uniprot id: B8GRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

396588:TGR7 RS01175
gene id: 396588:TGR7_RS01175
uniprot id: B8GU53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

396588:TGR7 RS11485
gene id: 396588:TGR7_RS11485
uniprot id: B8GV28
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS01165
gene id: 396588:TGR7_RS01165
uniprot id: B8GU51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS11965
gene id: 396588:TGR7_RS11965
uniprot id: B8GVB9
names: Similarity
messages: Belongs to the asparagine synthetase family.

396588:TGR7 RS01145
gene id: 396588:TGR7_RS01145
uniprot id: B8GU47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS13585
gene id: 396588:TGR7_RS13585
uniprot id: B8GMW5
names: Similarity
messages: Belongs to the UPF0250 family.

396588:TGR7 RS09280
gene id: 396588:TGR7_RS09280
uniprot id: B8GSN0
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

396588:TGR7 RS04410
gene id: 396588:TGR7_RS04410
uniprot id: B8GNC1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

396588:TGR7 RS05700
gene id: 396588:TGR7_RS05700
uniprot id: B8GPQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

396588:TGR7 RS09725
gene id: 396588:TGR7_RS09725
uniprot id: B8GT05
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

396588:TGR7 RS13380
gene id: 396588:TGR7_RS13380
uniprot id: B8GMS1
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS13660
gene id: 396588:TGR7_RS13660
uniprot id: B8GMY0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

396588:TGR7 RS13640
gene id: 396588:TGR7_RS13640
uniprot id: B8GMX6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

396588:TGR7 RS16140
gene id: 396588:TGR7_RS16140
uniprot id: B8GQR3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

396588:TGR7 RS00280
gene id: 396588:TGR7_RS00280
uniprot id: B8GTA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

396588:TGR7 RS11160
gene id: 396588:TGR7_RS11160
uniprot id: B8GUI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

396588:TGR7 RS11555
gene id: 396588:TGR7_RS11555
uniprot id: B8GV42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

396588:TGR7 RS09590
gene id: 396588:TGR7_RS09590
uniprot id: B8GSX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

396588:TGR7 RS00540
gene id: 396588:TGR7_RS00540
uniprot id: B8GTF2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

396588:TGR7 RS16050
gene id: 396588:TGR7_RS16050
uniprot id: B8GQP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family. CsoSCA subfamily.
messages: Carboxysome

396588:TGR7 RS11470
gene id: 396588:TGR7_RS11470
uniprot id: B8GV25
names: Similarity
messages: Belongs to the PhoH family.

396588:TGR7 RS01505
gene id: 396588:TGR7_RS01505
uniprot id: B8GUP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS04990
gene id: 396588:TGR7_RS04990
uniprot id: B8GNZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

396588:TGR7 RS10965
gene id: 396588:TGR7_RS10965
uniprot id: B8GUF1
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS13600
gene id: 396588:TGR7_RS13600
uniprot id: B8GMW8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

396588:TGR7 RS14905
gene id: 396588:TGR7_RS14905
uniprot id: B8GPC3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

396588:TGR7 RS10020
gene id: 396588:TGR7_RS10020
uniprot id: B8GT66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

396588:TGR7 RS01820
gene id: 396588:TGR7_RS01820
uniprot id: B8GUV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

396588:TGR7 RS05400
gene id: 396588:TGR7_RS05400
uniprot id: B8GPJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

396588:TGR7 RS09475
gene id: 396588:TGR7_RS09475
uniprot id: B8GSR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS11700
gene id: 396588:TGR7_RS11700
uniprot id: B8GV71
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS10770
gene id: 396588:TGR7_RS10770
uniprot id: B8GUB2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

396588:TGR7 RS03160
gene id: 396588:TGR7_RS03160
uniprot id: B8GLX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS07180
gene id: 396588:TGR7_RS07180
uniprot id: B8GRG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

396588:TGR7 RS07215
gene id: 396588:TGR7_RS07215
uniprot id: B8GRH0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

396588:TGR7 RS02540
gene id: 396588:TGR7_RS02540
uniprot id: B8GL93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

396588:TGR7 RS13385
gene id: 396588:TGR7_RS13385
uniprot id: B8GMS2
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS04940
gene id: 396588:TGR7_RS04940
uniprot id: B8GNY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

396588:TGR7 RS01765
gene id: 396588:TGR7_RS01765
uniprot id: B8GUU6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

396588:TGR7 RS16600
gene id: 396588:TGR7_RS16600
uniprot id: B8GRC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

396588:TGR7 RS12395
gene id: 396588:TGR7_RS12395
uniprot id: B8GLJ0
names: Similarity
messages: Belongs to the GppA/Ppx family.

396588:TGR7 RS11465
gene id: 396588:TGR7_RS11465
uniprot id: B8GV24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

396588:TGR7 RS14045
gene id: 396588:TGR7_RS14045
uniprot id: B8GNI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

396588:TGR7 RS03595
gene id: 396588:TGR7_RS03595
uniprot id: B8GMI7
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

396588:TGR7 RS01065
gene id: 396588:TGR7_RS01065
uniprot id: B8GU31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

396588:TGR7 RS08490
gene id: 396588:TGR7_RS08490
uniprot id: B8GS72
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

396588:TGR7 RS02575
gene id: 396588:TGR7_RS02575
uniprot id: B8GLA0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

396588:TGR7 RS00425
gene id: 396588:TGR7_RS00425
uniprot id: B8GTD0
names: Similarity
messages: Belongs to the LOG family.

396588:TGR7 RS05025
gene id: 396588:TGR7_RS05025
uniprot id: B8GP04
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

396588:TGR7 RS03475
gene id: 396588:TGR7_RS03475
uniprot id: B8GMG3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

396588:TGR7 RS15520
gene id: 396588:TGR7_RS15520
uniprot id: B8GQ15
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS05030
gene id: 396588:TGR7_RS05030
uniprot id: B8GP05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

396588:TGR7 RS06680
gene id: 396588:TGR7_RS06680
uniprot id: B8GQZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

396588:TGR7 RS04415
gene id: 396588:TGR7_RS04415
uniprot id: B8GNC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS09200
gene id: 396588:TGR7_RS09200
uniprot id: B8GSL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

396588:TGR7 RS06715
gene id: 396588:TGR7_RS06715
uniprot id: B8GR05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

396588:TGR7 RS14595
gene id: 396588:TGR7_RS14595
uniprot id: B8GP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

396588:TGR7 RS05285
gene id: 396588:TGR7_RS05285
uniprot id: B8GPH6
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS01390
gene id: 396588:TGR7_RS01390
uniprot id: B8GU97
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS11660
gene id: 396588:TGR7_RS11660
uniprot id: B8GV63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

396588:TGR7 RS13485
gene id: 396588:TGR7_RS13485
uniprot id: B8GMU3
names: Similarity
messages: Belongs to the MEMO1 family.

396588:TGR7 RS11590
gene id: 396588:TGR7_RS11590
uniprot id: B8GV49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

396588:TGR7 RS11280
gene id: 396588:TGR7_RS11280
uniprot id: B8GUL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

396588:TGR7 RS16090
gene id: 396588:TGR7_RS16090
uniprot id: B8GQQ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

396588:TGR7 RS01640
gene id: 396588:TGR7_RS01640
uniprot id: B8GUS0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

396588:TGR7 RS12215
gene id: 396588:TGR7_RS12215
uniprot id: B8GLF4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

396588:TGR7 RS15095
gene id: 396588:TGR7_RS15095
uniprot id: B8GPT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

396588:TGR7 RS11145
gene id: 396588:TGR7_RS11145
uniprot id: B8GUI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS16070
gene id: 396588:TGR7_RS16070
uniprot id: B8GQP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS06665
gene id: 396588:TGR7_RS06665
uniprot id: B8GQZ5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

396588:TGR7 RS11710
gene id: 396588:TGR7_RS11710
uniprot id: B8GV60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

396588:TGR7 RS01465
gene id: 396588:TGR7_RS01465
uniprot id: B8GUN5
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS10675
gene id: 396588:TGR7_RS10675
uniprot id: B8GTW9
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

396588:TGR7 RS10780
gene id: 396588:TGR7_RS10780
uniprot id: B8GUB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

396588:TGR7 RS14670
gene id: 396588:TGR7_RS14670
uniprot id: B8GP77
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

396588:TGR7 RS06670
gene id: 396588:TGR7_RS06670
uniprot id: B8GQZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

396588:TGR7 RS00200
gene id: 396588:TGR7_RS00200
uniprot id: B8GT85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

396588:TGR7 RS00945
gene id: 396588:TGR7_RS00945
uniprot id: B8GU07
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

396588:TGR7 RS01470
gene id: 396588:TGR7_RS01470
uniprot id: B8GUN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

396588:TGR7 RS13175
gene id: 396588:TGR7_RS13175
uniprot id: B8GMA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

396588:TGR7 RS10775
gene id: 396588:TGR7_RS10775
uniprot id: B8GUB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

396588:TGR7 RS11150
gene id: 396588:TGR7_RS11150
uniprot id: B8GUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

396588:TGR7 RS10040
gene id: 396588:TGR7_RS10040
uniprot id: B8GT70
names: Similarity
messages: Belongs to the AlaDH/PNT family.

396588:TGR7 RS10390
gene id: 396588:TGR7_RS10390
uniprot id: B8GTR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

396588:TGR7 RS05345
gene id: 396588:TGR7_RS05345
uniprot id: B8GPI8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS12330
gene id: 396588:TGR7_RS12330
uniprot id: B8GLH7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

396588:TGR7 RS04510
gene id: 396588:TGR7_RS04510
uniprot id: B8GND8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS03010
gene id: 396588:TGR7_RS03010
uniprot id: B8GLV0
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS15195
gene id: 396588:TGR7_RS15195
uniprot id: B8GPV4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

396588:TGR7 RS00005
gene id: 396588:TGR7_RS00005
uniprot id: B8GSS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

396588:TGR7 RS07850
gene id: 396588:TGR7_RS07850
uniprot id: B8GRU5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

396588:TGR7 RS05315
gene id: 396588:TGR7_RS05315
uniprot id: B8GPI2
names: Similarity
messages: Belongs to the UPF0225 family.

396588:TGR7 RS13210
gene id: 396588:TGR7_RS13210
uniprot id: B8GMB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

396588:TGR7 RS11615
gene id: 396588:TGR7_RS11615
uniprot id: B8GV54
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

396588:TGR7 RS00290
gene id: 396588:TGR7_RS00290
uniprot id: B8GTA3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

396588:TGR7 RS04980
gene id: 396588:TGR7_RS04980
uniprot id: B8GNZ6
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS09195
gene id: 396588:TGR7_RS09195
uniprot id: B8GSL3
names: Similarity
messages: Belongs to the fabD family.

396588:TGR7 RS07200
gene id: 396588:TGR7_RS07200
uniprot id: B8GRG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

396588:TGR7 RS06785
gene id: 396588:TGR7_RS06785
uniprot id: B8GR19
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

396588:TGR7 RS05040
gene id: 396588:TGR7_RS05040
uniprot id: B8GP07
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

396588:TGR7 RS13195
gene id: 396588:TGR7_RS13195
uniprot id: B8GMB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

396588:TGR7 RS15975
gene id: 396588:TGR7_RS15975
uniprot id: B8GQN0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

396588:TGR7 RS02880
gene id: 396588:TGR7_RS02880
uniprot id: B8GLS4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

396588:TGR7 RS00385
gene id: 396588:TGR7_RS00385
uniprot id: B8GTC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

396588:TGR7 RS06040
gene id: 396588:TGR7_RS06040
uniprot id: B8GQ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Membrane

396588:TGR7 RS06275
gene id: 396588:TGR7_RS06275
uniprot id: B8GQE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

396588:TGR7 RS07690
gene id: 396588:TGR7_RS07690
uniprot id: B8GRR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

396588:TGR7 RS11675
gene id: 396588:TGR7_RS11675
uniprot id: B8GV66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

396588:TGR7 RS16780
gene id: 396588:TGR7_RS16780
uniprot id: B8GSF6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

396588:TGR7 RS03945
gene id: 396588:TGR7_RS03945
uniprot id: B8GN29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS10375
gene id: 396588:TGR7_RS10375
uniprot id: B8GTQ7
names: Similarity
messages: Belongs to the disproportionating enzyme family.

396588:TGR7 RS16095
gene id: 396588:TGR7_RS16095
uniprot id: B8GQQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

396588:TGR7 RS06210
gene id: 396588:TGR7_RS06210
uniprot id: B8GQD2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

396588:TGR7 RS08000
gene id: 396588:TGR7_RS08000
uniprot id: B8GRX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

396588:TGR7 RS05410
gene id: 396588:TGR7_RS05410
uniprot id: B8GPK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

396588:TGR7 RS12815
gene id: 396588:TGR7_RS12815
uniprot id: B8GM40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
messages: Divalent metal cation.
messages: Homotrimer.

396588:TGR7 RS06860
gene id: 396588:TGR7_RS06860
uniprot id: B8GR34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

396588:TGR7 RS08600
gene id: 396588:TGR7_RS08600
uniprot id: B8GS94
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

396588:TGR7 RS06015
gene id: 396588:TGR7_RS06015
uniprot id: B8GQ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

396588:TGR7 RS06005
gene id: 396588:TGR7_RS06005
uniprot id: B8GQ91
names: Similarity
messages: Belongs to the SlyX family.

396588:TGR7 RS10275
gene id: 396588:TGR7_RS10275
uniprot id: B8GTN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

396588:TGR7 RS08505
gene id: 396588:TGR7_RS08505
uniprot id: B8GS75
names: Similarity
messages: Belongs to the GcvT family.

396588:TGR7 RS09775
gene id: 396588:TGR7_RS09775
uniprot id: B8GT15
names: Similarity
messages: Belongs to the archease family.

396588:TGR7 RS06675
gene id: 396588:TGR7_RS06675
uniprot id: B8GQZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

396588:TGR7 RS16335
gene id: 396588:TGR7_RS16335
uniprot id: B8GR70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

396588:TGR7 RS08050
gene id: 396588:TGR7_RS08050
uniprot id: B8GRY4
names: Similarity
messages: Belongs to the peptidase S49 family.

396588:TGR7 RS15045
gene id: 396588:TGR7_RS15045
uniprot id: B8GPF0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

396588:TGR7 RS09535
gene id: 396588:TGR7_RS09535
uniprot id: B8GSW9
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

396588:TGR7 RS03360
gene id: 396588:TGR7_RS03360
uniprot id: B8GME0
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

396588:TGR7 RS14810
gene id: 396588:TGR7_RS14810
uniprot id: B8GPA3
names: Similarity
messages: Belongs to the MoaD family.

396588:TGR7 RS10150
gene id: 396588:TGR7_RS10150
uniprot id: B8GTL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

396588:TGR7 RS06390
gene id: 396588:TGR7_RS06390
uniprot id: B8GQG8
names: Similarity
messages: Belongs to the HypE family.

396588:TGR7 RS01655
gene id: 396588:TGR7_RS01655
uniprot id: B8GUS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

396588:TGR7 RS13850
gene id: 396588:TGR7_RS13850
uniprot id: B8GNE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

396588:TGR7 RS05755
gene id: 396588:TGR7_RS05755
uniprot id: B8GPR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

396588:TGR7 RS15340
gene id: 396588:TGR7_RS15340
uniprot id: B8GPY0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

396588:TGR7 RS04915
gene id: 396588:TGR7_RS04915
uniprot id: B8GNY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

396588:TGR7 RS05280
gene id: 396588:TGR7_RS05280
uniprot id: B8GPH5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

396588:TGR7 RS01600
gene id: 396588:TGR7_RS01600
uniprot id: B8GUR2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

396588:TGR7 RS12640
gene id: 396588:TGR7_RS12640
uniprot id: B8GM07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

396588:TGR7 RS16330
gene id: 396588:TGR7_RS16330
uniprot id: B8GR69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

396588:TGR7 RS09455
gene id: 396588:TGR7_RS09455
uniprot id: B8GSR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

396588:TGR7 RS00630
gene id: 396588:TGR7_RS00630
uniprot id: B8GTH0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

396588:TGR7 RS03520
gene id: 396588:TGR7_RS03520
uniprot id: B8GMH2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

396588:TGR7 RS06460
gene id: 396588:TGR7_RS06460
uniprot id: B8GQV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

396588:TGR7 RS06310
gene id: 396588:TGR7_RS06310
uniprot id: B8GQF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

396588:TGR7 RS04845
gene id: 396588:TGR7_RS04845
uniprot id: B8GNX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

396588:TGR7 RS04640
gene id: 396588:TGR7_RS04640
uniprot id: B8GNT5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

396588:TGR7 RS03560
gene id: 396588:TGR7_RS03560
uniprot id: B8GMI0
names: Subcellular Location Annotation
messages: Cytoplasm

396588:TGR7 RS11525
gene id: 396588:TGR7_RS11525
uniprot id: B8GV35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

396588:TGR7 RS03600
gene id: 396588:TGR7_RS03600
uniprot id: B8GMI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

396588:TGR7 RS00450
gene id: 396588:TGR7_RS00450
uniprot id: B8GTD5
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS15115
gene id: 396588:TGR7_RS15115
uniprot id: B8GPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

396588:TGR7 RS16350
gene id: 396588:TGR7_RS16350
uniprot id: B8GR73
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

396588:TGR7 RS07745
gene id: 396588:TGR7_RS07745
uniprot id: B8GRS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

396588:TGR7 RS04865
gene id: 396588:TGR7_RS04865
uniprot id: B8GNX4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

396588:TGR7 RS13635
gene id: 396588:TGR7_RS13635
uniprot id: B8GMX5
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

396588:TGR7 RS10450
gene id: 396588:TGR7_RS10450
uniprot id: B8GTS1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

396588:TGR7 RS05555
gene id: 396588:TGR7_RS05555
uniprot id: B8GPM8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

396588:TGR7 RS04810
gene id: 396588:TGR7_RS04810
uniprot id: B8GNW3
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

396588:TGR7 RS03855
gene id: 396588:TGR7_RS03855
uniprot id: B8GMN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

396588:TGR7 RS10880
gene id: 396588:TGR7_RS10880
uniprot id: B8GUD4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

396588:TGR7 RS01180
gene id: 396588:TGR7_RS01180
uniprot id: B8GU54
names: Similarity
messages: Belongs to the GSP N family.

396588:TGR7 RS16390
gene id: 396588:TGR7_RS16390
uniprot id: B8GR81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS06415
gene id: 396588:TGR7_RS06415
uniprot id: B8GQH3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

396588:TGR7 RS06560
gene id: 396588:TGR7_RS06560
uniprot id: B8GQX4
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

396588:TGR7 RS15535
gene id: 396588:TGR7_RS15535
uniprot id: B8GQ18
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS09530
gene id: 396588:TGR7_RS09530
uniprot id: B8GSW8
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS03990
gene id: 396588:TGR7_RS03990
uniprot id: B8GN38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

396588:TGR7 RS10820
gene id: 396588:TGR7_RS10820
uniprot id: B8GUC2
names: Similarity
messages: Belongs to the histone deacetylase family.

396588:TGR7 RS02840
gene id: 396588:TGR7_RS02840
uniprot id: B8GLR6
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

396588:TGR7 RS07385
gene id: 396588:TGR7_RS07385
uniprot id: B8GRK2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

396588:TGR7 RS04465
gene id: 396588:TGR7_RS04465
uniprot id: B8GND2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

396588:TGR7 RS11125
gene id: 396588:TGR7_RS11125
uniprot id: B8GUI3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

396588:TGR7 RS09845
gene id: 396588:TGR7_RS09845
uniprot id: B8GT29
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

396588:TGR7 RS01595
gene id: 396588:TGR7_RS01595
uniprot id: B8GUR1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

396588:TGR7 RS04065
gene id: 396588:TGR7_RS04065
uniprot id: B8GN53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

396588:TGR7 RS00895
gene id: 396588:TGR7_RS00895
uniprot id: B8GTZ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

396588:TGR7 RS08445
gene id: 396588:TGR7_RS08445
uniprot id: B8GS63
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

396588:TGR7 RS02415
gene id: 396588:TGR7_RS02415
uniprot id: B8GL68
names: Similarity
messages: Belongs to the glutamate synthase family.

396588:TGR7 RS16580
gene id: 396588:TGR7_RS16580
uniprot id: B8GRB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

396588:TGR7 RS14575
gene id: 396588:TGR7_RS14575
uniprot id: B8GP58
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

396588:TGR7 RS14720
gene id: 396588:TGR7_RS14720
uniprot id: B8GP87
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

396588:TGR7 RS03060
gene id: 396588:TGR7_RS03060
uniprot id: B8GLV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

396588:TGR7 RS05840
gene id: 396588:TGR7_RS05840
uniprot id: B8GQ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

396588:TGR7 RS00455
gene id: 396588:TGR7_RS00455
uniprot id: B8GTD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

396588:TGR7 RS08815
gene id: 396588:TGR7_RS08815
uniprot id: B8GSD8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

396588:TGR7 RS01630
gene id: 396588:TGR7_RS01630
uniprot id: B8GUR8
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

396588:TGR7 RS04675
gene id: 396588:TGR7_RS04675
uniprot id: B8GNT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

396588:TGR7 RS03365
gene id: 396588:TGR7_RS03365
uniprot id: B8GME1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

396588:TGR7 RS08435
gene id: 396588:TGR7_RS08435
uniprot id: B8GS61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS05295
gene id: 396588:TGR7_RS05295
uniprot id: B8GPH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS01120
gene id: 396588:TGR7_RS01120
uniprot id: B8GU42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

396588:TGR7 RS03685
gene id: 396588:TGR7_RS03685
uniprot id: B8GMK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

396588:TGR7 RS06900
gene id: 396588:TGR7_RS06900
uniprot id: B8GR42
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

396588:TGR7 RS13925
gene id: 396588:TGR7_RS13925
uniprot id: B8GNF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

396588:TGR7 RS08530
gene id: 396588:TGR7_RS08530
uniprot id: B8GS80
names: Similarity
messages: Belongs to the glutamate synthase family.

396588:TGR7 RS12805
gene id: 396588:TGR7_RS12805
uniprot id: B8GM38
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS12185
gene id: 396588:TGR7_RS12185
uniprot id: B8GLE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS14815
gene id: 396588:TGR7_RS14815
uniprot id: B8GPA4
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

396588:TGR7 RS03530
gene id: 396588:TGR7_RS03530
uniprot id: B8GMH4
names: Similarity
messages: Belongs to the peptidase M1 family.

396588:TGR7 RS01835
gene id: 396588:TGR7_RS01835
uniprot id: B8GUW0
names: Similarity
messages: Belongs to the CutA family.

396588:TGR7 RS11400
gene id: 396588:TGR7_RS11400
uniprot id: B8GV11
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

396588:TGR7 RS11945
gene id: 396588:TGR7_RS11945
uniprot id: B8GVB5
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

396588:TGR7 RS07815
gene id: 396588:TGR7_RS07815
uniprot id: B8GRT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

396588:TGR7 RS03690
gene id: 396588:TGR7_RS03690
uniprot id: B8GMK6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

396588:TGR7 RS06320
gene id: 396588:TGR7_RS06320
uniprot id: B8GQF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

396588:TGR7 RS04975
gene id: 396588:TGR7_RS04975
uniprot id: B8GNZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

396588:TGR7 RS10130
gene id: 396588:TGR7_RS10130
uniprot id: B8GTK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

396588:TGR7 RS10395
gene id: 396588:TGR7_RS10395
uniprot id: B8GTR1
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

396588:TGR7 RS08805
gene id: 396588:TGR7_RS08805
uniprot id: B8GSD6
names: Similarity
messages: Belongs to the YkuD family.

396588:TGR7 RS06645
gene id: 396588:TGR7_RS06645
uniprot id: B8GQZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

396588:TGR7 RS11600
gene id: 396588:TGR7_RS11600
uniprot id: B8GV51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

396588:TGR7 RS03820
gene id: 396588:TGR7_RS03820
uniprot id: B8GMN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

396588:TGR7 RS11755
gene id: 396588:TGR7_RS11755
uniprot id: B8GV77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

396588:TGR7 RS13655
gene id: 396588:TGR7_RS13655
uniprot id: B8GMX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

396588:TGR7 RS11285
gene id: 396588:TGR7_RS11285
uniprot id: B8GUL4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

396588:TGR7 RS01395
gene id: 396588:TGR7_RS01395
uniprot id: B8GU98
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

396588:TGR7 RS16495
gene id: 396588:TGR7_RS16495
uniprot id: B8GRA1
names: Similarity
messages: Belongs to the peptidase S41A family.

396588:TGR7 RS02395
gene id: 396588:TGR7_RS02395
uniprot id: B8GL64
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

396588:TGR7 RS13755
gene id: 396588:TGR7_RS13755
uniprot id: B8GMZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

396588:TGR7 RS01060
gene id: 396588:TGR7_RS01060
uniprot id: B8GU30
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

396588:TGR7 RS11550
gene id: 396588:TGR7_RS11550
uniprot id: B8GV41
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

396588:TGR7 RS04450
gene id: 396588:TGR7_RS04450
uniprot id: B8GNC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

396588:TGR7 RS11845
gene id: 396588:TGR7_RS11845
uniprot id: B8GV95
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS06725
gene id: 396588:TGR7_RS06725
uniprot id: B8GR07
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

396588:TGR7 RS11390
gene id: 396588:TGR7_RS11390
uniprot id: B8GV09
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

396588:TGR7 RS02465
gene id: 396588:TGR7_RS02465
uniprot id: B8GL78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

396588:TGR7 RS05810
gene id: 396588:TGR7_RS05810
uniprot id: B8GQ52
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS05155
gene id: 396588:TGR7_RS05155
uniprot id: B8GP29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

396588:TGR7 RS00500
gene id: 396588:TGR7_RS00500
uniprot id: B8GTE4
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS13650
gene id: 396588:TGR7_RS13650
uniprot id: B8GMX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

396588:TGR7 RS10305
gene id: 396588:TGR7_RS10305
uniprot id: B8GTP4
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

396588:TGR7 RS06355
gene id: 396588:TGR7_RS06355
uniprot id: B8GQG1
names: Similarity
messages: Belongs to the HupH/HyaF family.

396588:TGR7 RS03705
gene id: 396588:TGR7_RS03705
uniprot id: B8GMK9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

396588:TGR7 RS16015
gene id: 396588:TGR7_RS16015
uniprot id: B8GQN8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

396588:TGR7 RS09540
gene id: 396588:TGR7_RS09540
uniprot id: B8GSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

396588:TGR7 RS10095
gene id: 396588:TGR7_RS10095
uniprot id: B8GT81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS06695
gene id: 396588:TGR7_RS06695
uniprot id: B8GR01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

396588:TGR7 RS00975
gene id: 396588:TGR7_RS00975
uniprot id: B8GU13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

396588:TGR7 RS08360
gene id: 396588:TGR7_RS08360
uniprot id: B8GS47
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

396588:TGR7 RS15220
gene id: 396588:TGR7_RS15220
uniprot id: B8GPV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

396588:TGR7 RS16060
gene id: 396588:TGR7_RS16060
uniprot id: B8GQP7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

396588:TGR7 RS06765
gene id: 396588:TGR7_RS06765
uniprot id: B8GR15
names: Similarity
messages: Belongs to the type III secretion exporter family.

396588:TGR7 RS09650
gene id: 396588:TGR7_RS09650
uniprot id: B8GSZ0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

396588:TGR7 RS02385
gene id: 396588:TGR7_RS02385
uniprot id: B8GL62
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

396588:TGR7 RS13490
gene id: 396588:TGR7_RS13490
uniprot id: B8GMU4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

396588:TGR7 RS15590
gene id: 396588:TGR7_RS15590
uniprot id: B8GQ29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

396588:TGR7 RS00970
gene id: 396588:TGR7_RS00970
uniprot id: B8GU12
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

396588:TGR7 RS00590
gene id: 396588:TGR7_RS00590
uniprot id: B8GTG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

396588:TGR7 RS09615
gene id: 396588:TGR7_RS09615
uniprot id: B8GSY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

396588:TGR7 RS05480
gene id: 396588:TGR7_RS05480
uniprot id: B8GPL3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

396588:TGR7 RS08660
gene id: 396588:TGR7_RS08660
uniprot id: B8GSA7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

396588:TGR7 RS07950
gene id: 396588:TGR7_RS07950
uniprot id: B8GRW3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

396588:TGR7 RS12495
gene id: 396588:TGR7_RS12495
uniprot id: B8GLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

396588:TGR7 RS05825
gene id: 396588:TGR7_RS05825
uniprot id: B8GQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

396588:TGR7 RS05890
gene id: 396588:TGR7_RS05890
uniprot id: B8GQ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

396588:TGR7 RS04210
gene id: 396588:TGR7_RS04210
uniprot id: B8GN82
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

396588:TGR7 RS15085
gene id: 396588:TGR7_RS15085
uniprot id: B8GPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

396588:TGR7 RS11610
gene id: 396588:TGR7_RS11610
uniprot id: B8GV53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

396588:TGR7 RS05010
gene id: 396588:TGR7_RS05010
uniprot id: B8GP01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

396588:TGR7 RS15525
gene id: 396588:TGR7_RS15525
uniprot id: B8GQ16
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS10310
gene id: 396588:TGR7_RS10310
uniprot id: B8GTP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

396588:TGR7 RS02835
gene id: 396588:TGR7_RS02835
uniprot id: B8GLR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

396588:TGR7 RS12615
gene id: 396588:TGR7_RS12615
uniprot id: B8GLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane

396588:TGR7 RS10325
gene id: 396588:TGR7_RS10325
uniprot id: B8GTP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS01000
gene id: 396588:TGR7_RS01000
uniprot id: B8GU18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

396588:TGR7 RS12520
gene id: 396588:TGR7_RS12520
uniprot id: B8GLL3
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS07675
gene id: 396588:TGR7_RS07675
uniprot id: B8GRR0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

396588:TGR7 RS05965
gene id: 396588:TGR7_RS05965
uniprot id: B8GQ83
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

396588:TGR7 RS02600
gene id: 396588:TGR7_RS02600
uniprot id: B8GLA5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

396588:TGR7 RS12880
gene id: 396588:TGR7_RS12880
uniprot id: B8GM53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

396588:TGR7 RS16615
gene id: 396588:TGR7_RS16615
uniprot id: B8GRC6
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

396588:TGR7 RS00410
gene id: 396588:TGR7_RS00410
uniprot id: B8GTC7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

396588:TGR7 RS01170
gene id: 396588:TGR7_RS01170
uniprot id: B8GU52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

396588:TGR7 RS10650
gene id: 396588:TGR7_RS10650
uniprot id: B8GTW4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

396588:TGR7 RS07665
gene id: 396588:TGR7_RS07665
uniprot id: B8GRQ8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

396588:TGR7 RS00515
gene id: 396588:TGR7_RS00515
uniprot id: B8GTE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

396588:TGR7 RS11565
gene id: 396588:TGR7_RS11565
uniprot id: B8GV44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

396588:TGR7 RS04000
gene id: 396588:TGR7_RS04000
uniprot id: B8GN40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

396588:TGR7 RS09825
gene id: 396588:TGR7_RS09825
uniprot id: B8GT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS04355
gene id: 396588:TGR7_RS04355
uniprot id: B8GNB1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

396588:TGR7 RS01415
gene id: 396588:TGR7_RS01415
uniprot id: B8GUA2
names: Similarity
messages: Belongs to the pirin family.

396588:TGR7 RS05835
gene id: 396588:TGR7_RS05835
uniprot id: B8GQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

396588:TGR7 RS11540
gene id: 396588:TGR7_RS11540
uniprot id: B8GV39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

396588:TGR7 RS04440
gene id: 396588:TGR7_RS04440
uniprot id: B8GNC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

396588:TGR7 RS07485
gene id: 396588:TGR7_RS07485
uniprot id: B8GRM2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

396588:TGR7 RS14510
gene id: 396588:TGR7_RS14510
uniprot id: B8GP45
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

396588:TGR7 RS16410
gene id: 396588:TGR7_RS16410
uniprot id: B8GR85
names: Similarity
messages: Belongs to the GSP E family.

396588:TGR7 RS10730
gene id: 396588:TGR7_RS10730
uniprot id: B8GTY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

396588:TGR7 RS00010
gene id: 396588:TGR7_RS00010
uniprot id: B8GSS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

396588:TGR7 RS09730
gene id: 396588:TGR7_RS09730
uniprot id: B8GT06
names: Similarity
messages: Belongs to the YoeB family.

396588:TGR7 RS15050
gene id: 396588:TGR7_RS15050
uniprot id: B8GPF1
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS06545
gene id: 396588:TGR7_RS06545
uniprot id: B8GQX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS13415
gene id: 396588:TGR7_RS13415
uniprot id: B8GMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS08785
gene id: 396588:TGR7_RS08785
uniprot id: B8GSD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

396588:TGR7 RS15790
gene id: 396588:TGR7_RS15790
uniprot id: B8GQJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

396588:TGR7 RS04120
gene id: 396588:TGR7_RS04120
uniprot id: B8GN64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

396588:TGR7 RS13305
gene id: 396588:TGR7_RS13305
uniprot id: B8GMQ7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

396588:TGR7 RS00545
gene id: 396588:TGR7_RS00545
uniprot id: B8GTF3
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS13695
gene id: 396588:TGR7_RS13695
uniprot id: B8GMY8
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

396588:TGR7 RS05610
gene id: 396588:TGR7_RS05610
uniprot id: B8GPN9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

396588:TGR7 RS11475
gene id: 396588:TGR7_RS11475
uniprot id: B8GV26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

396588:TGR7 RS06890
gene id: 396588:TGR7_RS06890
uniprot id: B8GR40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

396588:TGR7 RS03760
gene id: 396588:TGR7_RS03760
uniprot id: B8GMM0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

396588:TGR7 RS12340
gene id: 396588:TGR7_RS12340
uniprot id: B8GLH9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

396588:TGR7 RS11750
gene id: 396588:TGR7_RS11750
uniprot id: B8GV76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

396588:TGR7 RS13990
gene id: 396588:TGR7_RS13990
uniprot id: B8GNH0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

396588:TGR7 RS00855
gene id: 396588:TGR7_RS00855
uniprot id: B8GTY8
names: Subcellular Location Annotation
messages: Cytoplasm

396588:TGR7 RS13520
gene id: 396588:TGR7_RS13520
uniprot id: B8GMV0
names: Similarity
messages: Belongs to the BolA/IbaG family.

396588:TGR7 RS12385
gene id: 396588:TGR7_RS12385
uniprot id: B8GLI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

396588:TGR7 RS04105
gene id: 396588:TGR7_RS04105
uniprot id: B8GN61
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

396588:TGR7 RS09880
gene id: 396588:TGR7_RS09880
uniprot id: B8GT36
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

396588:TGR7 RS11620
gene id: 396588:TGR7_RS11620
uniprot id: B8GV55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

396588:TGR7 RS16510
gene id: 396588:TGR7_RS16510
uniprot id: B8GRA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

396588:TGR7 RS14450
gene id: 396588:TGR7_RS14450
uniprot id: B8GNR2
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS08515
gene id: 396588:TGR7_RS08515
uniprot id: B8GS77
names: Similarity
messages: Belongs to the glutamine synthetase family.

396588:TGR7 RS03055
gene id: 396588:TGR7_RS03055
uniprot id: B8GLV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS15985
gene id: 396588:TGR7_RS15985
uniprot id: B8GQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

396588:TGR7 RS13995
gene id: 396588:TGR7_RS13995
uniprot id: B8GNH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

396588:TGR7 RS11230
gene id: 396588:TGR7_RS11230
uniprot id: B8GUK3
names: Similarity
messages: Belongs to the acylphosphatase family.

396588:TGR7 RS01070
gene id: 396588:TGR7_RS01070
uniprot id: B8GU32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

396588:TGR7 RS06520
gene id: 396588:TGR7_RS06520
uniprot id: B8GQW7
names: Similarity
messages: Belongs to the citrate synthase family.

396588:TGR7 RS12820
gene id: 396588:TGR7_RS12820
uniprot id: B8GM41
names: Cofactor
messages: Can also use Mn(2+) ion.

396588:TGR7 RS03780
gene id: 396588:TGR7_RS03780
uniprot id: B8GMM4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS10355
gene id: 396588:TGR7_RS10355
uniprot id: B8GTQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

396588:TGR7 RS15165
gene id: 396588:TGR7_RS15165
uniprot id: B8GL16
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

396588:TGR7 RS01495
gene id: 396588:TGR7_RS01495
uniprot id: B8GUP1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

396588:TGR7 RS00880
gene id: 396588:TGR7_RS00880
uniprot id: B8GTZ3
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

396588:TGR7 RS12165
gene id: 396588:TGR7_RS12165
uniprot id: B8GLE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS05765
gene id: 396588:TGR7_RS05765
uniprot id: B8GPS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

396588:TGR7 RS15090
gene id: 396588:TGR7_RS15090
uniprot id: B8GPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

396588:TGR7 RS02560
gene id: 396588:TGR7_RS02560
uniprot id: B8GL97
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

396588:TGR7 RS11410
gene id: 396588:TGR7_RS11410
uniprot id: B8GV13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

396588:TGR7 RS10640
gene id: 396588:TGR7_RS10640
uniprot id: B8GTW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

396588:TGR7 RS01760
gene id: 396588:TGR7_RS01760
uniprot id: B8GUU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

396588:TGR7 RS10250
gene id: 396588:TGR7_RS10250
uniprot id: B8GTN3
names: Similarity
messages: Belongs to the YfgM family.

396588:TGR7 RS03720
gene id: 396588:TGR7_RS03720
uniprot id: B8GML2
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

396588:TGR7 RS03240
gene id: 396588:TGR7_RS03240
uniprot id: B8GLZ6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

396588:TGR7 RS05385
gene id: 396588:TGR7_RS05385
uniprot id: B8GPJ5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

396588:TGR7 RS11685
gene id: 396588:TGR7_RS11685
uniprot id: B8GV68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

396588:TGR7 RS09485
gene id: 396588:TGR7_RS09485
uniprot id: B8GSS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

396588:TGR7 RS12350
gene id: 396588:TGR7_RS12350
uniprot id: B8GLI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

396588:TGR7 RS10795
gene id: 396588:TGR7_RS10795
uniprot id: B8GUB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

396588:TGR7 RS12670
gene id: 396588:TGR7_RS12670
uniprot id: B8GM13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS16475
gene id: 396588:TGR7_RS16475
uniprot id: B8GR97
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

396588:TGR7 RS13785
gene id: 396588:TGR7_RS13785
uniprot id: B8GN05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

396588:TGR7 RS06100
gene id: 396588:TGR7_RS06100
uniprot id: B8GQB0
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

396588:TGR7 RS14990
gene id: 396588:TGR7_RS14990
uniprot id: B8GPD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

396588:TGR7 RS03890
gene id: 396588:TGR7_RS03890
uniprot id: B8GN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS04970
gene id: 396588:TGR7_RS04970
uniprot id: B8GNZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

396588:TGR7 RS05100
gene id: 396588:TGR7_RS05100
uniprot id: B8GP17
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS09605
gene id: 396588:TGR7_RS09605
uniprot id: B8GSY1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

396588:TGR7 RS07720
gene id: 396588:TGR7_RS07720
uniprot id: B8GRR9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

396588:TGR7 RS11190
gene id: 396588:TGR7_RS11190
uniprot id: B8GUJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

396588:TGR7 RS03210
gene id: 396588:TGR7_RS03210
uniprot id: B8GLY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

396588:TGR7 RS11560
gene id: 396588:TGR7_RS11560
uniprot id: B8GV43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

396588:TGR7 RS13375
gene id: 396588:TGR7_RS13375
uniprot id: B8GMS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS10290
gene id: 396588:TGR7_RS10290
uniprot id: B8GTP1
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

396588:TGR7 RS09185
gene id: 396588:TGR7_RS09185
uniprot id: B8GSL1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

396588:TGR7 RS11025
gene id: 396588:TGR7_RS11025
uniprot id: B8GUG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

396588:TGR7 RS03810
gene id: 396588:TGR7_RS03810
uniprot id: B8GMN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

396588:TGR7 RS05705
gene id: 396588:TGR7_RS05705
uniprot id: B8GPQ8
names: Similarity
messages: Belongs to the peptidase A31 family.

396588:TGR7 RS07540
gene id: 396588:TGR7_RS07540
uniprot id: B8GRN3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

396588:TGR7 RS05885
gene id: 396588:TGR7_RS05885
uniprot id: B8GQ67
names: Subcellular Location Annotation
messages: Cytoplasm

396588:TGR7 RS06730
gene id: 396588:TGR7_RS06730
uniprot id: B8GR08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

396588:TGR7 RS05425
gene id: 396588:TGR7_RS05425
uniprot id: B8GPK2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

396588:TGR7 RS13225
gene id: 396588:TGR7_RS13225
uniprot id: B8GMB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

396588:TGR7 RS11270
gene id: 396588:TGR7_RS11270
uniprot id: B8GUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

396588:TGR7 RS11250
gene id: 396588:TGR7_RS11250
uniprot id: B8GUK7
names: Similarity
messages: Belongs to the WrbA family.

396588:TGR7 RS04100
gene id: 396588:TGR7_RS04100
uniprot id: B8GN60
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

396588:TGR7 RS15345
gene id: 396588:TGR7_RS15345
uniprot id: B8GPY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

396588:TGR7 RS11245
gene id: 396588:TGR7_RS11245
uniprot id: B8GUK6
names: Similarity
messages: Belongs to the ArsC family.

396588:TGR7 RS04695
gene id: 396588:TGR7_RS04695
uniprot id: B8GNU1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

396588:TGR7 RS10230
gene id: 396588:TGR7_RS10230
uniprot id: B8GTM9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

396588:TGR7 RS04050
gene id: 396588:TGR7_RS04050
uniprot id: B8GN50
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS12970
gene id: 396588:TGR7_RS12970
uniprot id: B8GM70
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

396588:TGR7 RS07570
gene id: 396588:TGR7_RS07570
uniprot id: B8GRN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

396588:TGR7 RS08680
gene id: 396588:TGR7_RS08680
uniprot id: B8GSB1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

396588:TGR7 RS13400
gene id: 396588:TGR7_RS13400
uniprot id: B8GMS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

396588:TGR7 RS03865
gene id: 396588:TGR7_RS03865
uniprot id: B8GMP1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

396588:TGR7 RS07340
gene id: 396588:TGR7_RS07340
uniprot id: B8GRJ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS11585
gene id: 396588:TGR7_RS11585
uniprot id: B8GV48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

396588:TGR7 RS05860
gene id: 396588:TGR7_RS05860
uniprot id: B8GQ62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

396588:TGR7 RS04855
gene id: 396588:TGR7_RS04855
uniprot id: B8GNX2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

396588:TGR7 RS02830
gene id: 396588:TGR7_RS02830
uniprot id: B8GLR4
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

396588:TGR7 RS10320
gene id: 396588:TGR7_RS10320
uniprot id: B8GTP7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

396588:TGR7 RS07425
gene id: 396588:TGR7_RS07425
uniprot id: B8GRL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS16255
gene id: 396588:TGR7_RS16255
uniprot id: B8GQT3
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS03805
gene id: 396588:TGR7_RS03805
uniprot id: B8GMM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

396588:TGR7 RS14050
gene id: 396588:TGR7_RS14050
uniprot id: B8GNI2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

396588:TGR7 RS02970
gene id: 396588:TGR7_RS02970
uniprot id: B8GLU2
names: Similarity
messages: Belongs to the HsdR family.

396588:TGR7 RS11595
gene id: 396588:TGR7_RS11595
uniprot id: B8GV50
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

396588:TGR7 RS06265
gene id: 396588:TGR7_RS06265
uniprot id: B8GQE3
names: Similarity
messages: Belongs to the TrpF family.

396588:TGR7 RS08075
gene id: 396588:TGR7_RS08075
uniprot id: B8GRY9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

396588:TGR7 RS10600
gene id: 396588:TGR7_RS10600
uniprot id: B8GTV4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

396588:TGR7 RS14460
gene id: 396588:TGR7_RS14460
uniprot id: B8GP35
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS15385
gene id: 396588:TGR7_RS15385
uniprot id: B8GPY9
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

396588:TGR7 RS00055
gene id: 396588:TGR7_RS00055
uniprot id: B8GST1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

396588:TGR7 RS11385
gene id: 396588:TGR7_RS11385
uniprot id: B8GV08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

396588:TGR7 RS11575
gene id: 396588:TGR7_RS11575
uniprot id: B8GV46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

396588:TGR7 RS11195
gene id: 396588:TGR7_RS11195
uniprot id: B8GUJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

396588:TGR7 RS12190
gene id: 396588:TGR7_RS12190
uniprot id: B8GLE9
names: Similarity
messages: Belongs to the thioredoxin family.

396588:TGR7 RS03590
gene id: 396588:TGR7_RS03590
uniprot id: B8GMI6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

396588:TGR7 RS15000
gene id: 396588:TGR7_RS15000
uniprot id: B8GPE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

396588:TGR7 RS00140
gene id: 396588:TGR7_RS00140
uniprot id: B8GSU7
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

396588:TGR7 RS07080
gene id: 396588:TGR7_RS07080
uniprot id: B8GRE3
names: Subcellular Location Annotation
messages: Cytoplasm

396588:TGR7 RS06150
gene id: 396588:TGR7_RS06150
uniprot id: B8GQC0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS06660
gene id: 396588:TGR7_RS06660
uniprot id: B8GQZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

396588:TGR7 RS12310
gene id: 396588:TGR7_RS12310
uniprot id: B8GLH3
names: Similarity
messages: Belongs to the MlaA family.

396588:TGR7 RS10710
gene id: 396588:TGR7_RS10710
uniprot id: B8GTX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

396588:TGR7 RS03710
gene id: 396588:TGR7_RS03710
uniprot id: B8GML0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

396588:TGR7 RS05160
gene id: 396588:TGR7_RS05160
uniprot id: B8GP30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

396588:TGR7 RS14630
gene id: 396588:TGR7_RS14630
uniprot id: B8GP69
names: Similarity
messages: Belongs to the GSP E family.

396588:TGR7 RS04400
gene id: 396588:TGR7_RS04400
uniprot id: B8GNB9
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS06650
gene id: 396588:TGR7_RS06650
uniprot id: B8GQZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

396588:TGR7 RS14655
gene id: 396588:TGR7_RS14655
uniprot id: B8GP74
names: Similarity
messages: Belongs to the YggT family.

396588:TGR7 RS00780
gene id: 396588:TGR7_RS00780
uniprot id: B8GTJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

396588:TGR7 RS04205
gene id: 396588:TGR7_RS04205
uniprot id: B8GN81
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

396588:TGR7 RS04310
gene id: 396588:TGR7_RS04310
uniprot id: B8GNA2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS06225
gene id: 396588:TGR7_RS06225
uniprot id: B8GQD5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS12160
gene id: 396588:TGR7_RS12160
uniprot id: B8GLE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

396588:TGR7 RS06685
gene id: 396588:TGR7_RS06685
uniprot id: B8GQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

396588:TGR7 RS14165
gene id: 396588:TGR7_RS14165
uniprot id: B8GNK5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

396588:TGR7 RS09525
gene id: 396588:TGR7_RS09525
uniprot id: B8GSW7
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS01125
gene id: 396588:TGR7_RS01125
uniprot id: B8GU43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

396588:TGR7 RS16065
gene id: 396588:TGR7_RS16065
uniprot id: B8GQP8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

396588:TGR7 RS04825
gene id: 396588:TGR7_RS04825
uniprot id: B8GNW6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS05795
gene id: 396588:TGR7_RS05795
uniprot id: B8GPS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

396588:TGR7 RS06780
gene id: 396588:TGR7_RS06780
uniprot id: B8GR18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

396588:TGR7 RS09600
gene id: 396588:TGR7_RS09600
uniprot id: B8GSY0
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

396588:TGR7 RS04275
gene id: 396588:TGR7_RS04275
uniprot id: B8GN95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

396588:TGR7 RS16610
gene id: 396588:TGR7_RS16610
uniprot id: B8GRC5
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS11480
gene id: 396588:TGR7_RS11480
uniprot id: B8GV27
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

396588:TGR7 RS08570
gene id: 396588:TGR7_RS08570
uniprot id: B8GS88
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

396588:TGR7 RS01035
gene id: 396588:TGR7_RS01035
uniprot id: B8GU25
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS06110
gene id: 396588:TGR7_RS06110
uniprot id: B8GQB2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

396588:TGR7 RS04930
gene id: 396588:TGR7_RS04930
uniprot id: B8GNY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

396588:TGR7 RS04315
gene id: 396588:TGR7_RS04315
uniprot id: B8GNA3
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

396588:TGR7 RS04880
gene id: 396588:TGR7_RS04880
uniprot id: B8GNX7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

396588:TGR7 RS06450
gene id: 396588:TGR7_RS06450
uniprot id: B8GQV5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

396588:TGR7 RS10520
gene id: 396588:TGR7_RS10520
uniprot id: B8GL16
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

396588:TGR7 RS05455
gene id: 396588:TGR7_RS05455
uniprot id: B8GPK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

396588:TGR7 RS09495
gene id: 396588:TGR7_RS09495
uniprot id: B8GSW1
names: Similarity
messages: Belongs to the GSP E family.

396588:TGR7 RS13420
gene id: 396588:TGR7_RS13420
uniprot id: B8GMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS11805
gene id: 396588:TGR7_RS11805
uniprot id: B8GV89
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS16630
gene id: 396588:TGR7_RS16630
uniprot id: B8GRC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

396588:TGR7 RS13920
gene id: 396588:TGR7_RS13920
uniprot id: B8GNF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

396588:TGR7 RS04735
gene id: 396588:TGR7_RS04735
uniprot id: B8GNU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS07710
gene id: 396588:TGR7_RS07710
uniprot id: B8GRR7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

396588:TGR7 RS12700
gene id: 396588:TGR7_RS12700
uniprot id: B8GM19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

396588:TGR7 RS02320
gene id: 396588:TGR7_RS02320
uniprot id: B8GL50
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS09840
gene id: 396588:TGR7_RS09840
uniprot id: B8GT28
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS10490
gene id: 396588:TGR7_RS10490
uniprot id: B8GTS9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS07830
gene id: 396588:TGR7_RS07830
uniprot id: B8GRU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

396588:TGR7 RS02650
gene id: 396588:TGR7_RS02650
uniprot id: B8GLB3
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

396588:TGR7 RS14470
gene id: 396588:TGR7_RS14470
uniprot id: B8GP37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

396588:TGR7 RS07360
gene id: 396588:TGR7_RS07360
uniprot id: B8GRJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS14940
gene id: 396588:TGR7_RS14940
uniprot id: B8GPC8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

396588:TGR7 RS06735
gene id: 396588:TGR7_RS06735
uniprot id: B8GR09
names: Similarity
messages: Belongs to the MotB family.

396588:TGR7 RS16105
gene id: 396588:TGR7_RS16105
uniprot id: B8GQQ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

396588:TGR7 RS03345
gene id: 396588:TGR7_RS03345
uniprot id: B8GMD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

396588:TGR7 RS14550
gene id: 396588:TGR7_RS14550
uniprot id: B8GP53
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

396588:TGR7 RS02510
gene id: 396588:TGR7_RS02510
uniprot id: B8GL87
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

396588:TGR7 RS09910
gene id: 396588:TGR7_RS09910
uniprot id: B8GT44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

396588:TGR7 RS16465
gene id: 396588:TGR7_RS16465
uniprot id: B8GR95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

396588:TGR7 RS09300
gene id: 396588:TGR7_RS09300
uniprot id: B8GSN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

396588:TGR7 RS09020
gene id: 396588:TGR7_RS09020
uniprot id: B8GSH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

396588:TGR7 RS11580
gene id: 396588:TGR7_RS11580
uniprot id: B8GV47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

396588:TGR7 RS04875
gene id: 396588:TGR7_RS04875
uniprot id: B8GNX6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS09780
gene id: 396588:TGR7_RS09780
uniprot id: B8GT16
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

396588:TGR7 RS00920
gene id: 396588:TGR7_RS00920
uniprot id: B8GU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

396588:TGR7 RS11645
gene id: 396588:TGR7_RS11645
uniprot id: B8GV60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

396588:TGR7 RS11185
gene id: 396588:TGR7_RS11185
uniprot id: B8GUJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

396588:TGR7 RS04180
gene id: 396588:TGR7_RS04180
uniprot id: B8GN76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

396588:TGR7 RS15625
gene id: 396588:TGR7_RS15625
uniprot id: B8GQ36
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS02745
gene id: 396588:TGR7_RS02745
uniprot id: B8GLP6
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

396588:TGR7 RS02455
gene id: 396588:TGR7_RS02455
uniprot id: B8GL76
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

396588:TGR7 RS14900
gene id: 396588:TGR7_RS14900
uniprot id: B8GPC2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

396588:TGR7 RS00075
gene id: 396588:TGR7_RS00075
uniprot id: B8GST4
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

396588:TGR7 RS14435
gene id: 396588:TGR7_RS14435
uniprot id: B8GNQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

396588:TGR7 RS01110
gene id: 396588:TGR7_RS01110
uniprot id: B8GU40
names: Similarity
messages: Belongs to the GSP C family.

396588:TGR7 RS14445
gene id: 396588:TGR7_RS14445
uniprot id: B8GNR1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

396588:TGR7 RS04625
gene id: 396588:TGR7_RS04625
uniprot id: B8GNT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS06635
gene id: 396588:TGR7_RS06635
uniprot id: B8GQY9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

396588:TGR7 RS02220
gene id: 396588:TGR7_RS02220
uniprot id: B8GL29
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

396588:TGR7 RS16655
gene id: 396588:TGR7_RS16655
uniprot id: B8GRD4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

396588:TGR7 RS06370
gene id: 396588:TGR7_RS06370
uniprot id: B8GQG4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

396588:TGR7 RS07260
gene id: 396588:TGR7_RS07260
uniprot id: B8GRH9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

396588:TGR7 RS06960
gene id: 396588:TGR7_RS06960
uniprot id: B8GR53
names: Similarity
messages: Belongs to the CFA/CMAS family.

396588:TGR7 RS01400
gene id: 396588:TGR7_RS01400
uniprot id: B8GU99
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

396588:TGR7 RS06295
gene id: 396588:TGR7_RS06295
uniprot id: B8GQE9
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS13895
gene id: 396588:TGR7_RS13895
uniprot id: B8GNF2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

396588:TGR7 RS06435
gene id: 396588:TGR7_RS06435
uniprot id: B8GQV2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

396588:TGR7 RS04595
gene id: 396588:TGR7_RS04595
uniprot id: B8GNS6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

396588:TGR7 RS00430
gene id: 396588:TGR7_RS00430
uniprot id: B8GTD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

396588:TGR7 RS09165
gene id: 396588:TGR7_RS09165
uniprot id: B8GSK7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

396588:TGR7 RS13810
gene id: 396588:TGR7_RS13810
uniprot id: B8GN10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Periplasm

396588:TGR7 RS15370
gene id: 396588:TGR7_RS15370
uniprot id: B8GPY6
names: Similarity
messages: Belongs to the histone deacetylase family.

396588:TGR7 RS13830
gene id: 396588:TGR7_RS13830
uniprot id: B8GN14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

396588:TGR7 RS12095
gene id: 396588:TGR7_RS12095
uniprot id: B8GLD0
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

396588:TGR7 RS13795
gene id: 396588:TGR7_RS13795
uniprot id: B8GN07
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

396588:TGR7 RS06845
gene id: 396588:TGR7_RS06845
uniprot id: B8GR31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

396588:TGR7 RS05420
gene id: 396588:TGR7_RS05420
uniprot id: B8GPK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

396588:TGR7 RS02620
gene id: 396588:TGR7_RS02620
uniprot id: B8GLA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

396588:TGR7 RS03485
gene id: 396588:TGR7_RS03485
uniprot id: B8GMG5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

396588:TGR7 RS04340
gene id: 396588:TGR7_RS04340
uniprot id: B8GNA8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

396588:TGR7 RS10285
gene id: 396588:TGR7_RS10285
uniprot id: B8GTP0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

396588:TGR7 RS06880
gene id: 396588:TGR7_RS06880
uniprot id: B8GR38
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

396588:TGR7 RS00020
gene id: 396588:TGR7_RS00020
uniprot id: B8GSS4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

396588:TGR7 RS03700
gene id: 396588:TGR7_RS03700
uniprot id: B8GMK8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

396588:TGR7 RS00730
gene id: 396588:TGR7_RS00730
uniprot id: B8GTI8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS07435
gene id: 396588:TGR7_RS07435
uniprot id: B8GRL2
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

396588:TGR7 RS12125
gene id: 396588:TGR7_RS12125
uniprot id: B8GLD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

396588:TGR7 RS04925
gene id: 396588:TGR7_RS04925
uniprot id: B8GNY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

396588:TGR7 RS10210
gene id: 396588:TGR7_RS10210
uniprot id: B8GTM5
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

396588:TGR7 RS15700
gene id: 396588:TGR7_RS15700
uniprot id: B8GQH4
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS00950
gene id: 396588:TGR7_RS00950
uniprot id: B8GU08
names: Similarity
messages: Belongs to the Smg family.

396588:TGR7 RS06350
gene id: 396588:TGR7_RS06350
uniprot id: B8GQG0
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

396588:TGR7 RS11265
gene id: 396588:TGR7_RS11265
uniprot id: B8GUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

396588:TGR7 RS03070
gene id: 396588:TGR7_RS03070
uniprot id: B8GLW0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

396588:TGR7 RS09585
gene id: 396588:TGR7_RS09585
uniprot id: B8GSX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

396588:TGR7 RS12465
gene id: 396588:TGR7_RS12465
uniprot id: B8GLK3
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

396588:TGR7 RS11640
gene id: 396588:TGR7_RS11640
uniprot id: B8GV59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

396588:TGR7 RS10340
gene id: 396588:TGR7_RS10340
uniprot id: B8GTQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

396588:TGR7 RS00040
gene id: 396588:TGR7_RS00040
uniprot id: B8GSS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

396588:TGR7 RS10350
gene id: 396588:TGR7_RS10350
uniprot id: B8GTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS07955
gene id: 396588:TGR7_RS07955
uniprot id: B8GRW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

396588:TGR7 RS07780
gene id: 396588:TGR7_RS07780
uniprot id: B8GRT1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

396588:TGR7 RS09885
gene id: 396588:TGR7_RS09885
uniprot id: B8GT38
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS13860
gene id: 396588:TGR7_RS13860
uniprot id: B8GNE5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

396588:TGR7 RS04470
gene id: 396588:TGR7_RS04470
uniprot id: B8GND3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

396588:TGR7 RS10385
gene id: 396588:TGR7_RS10385
uniprot id: B8GTQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

396588:TGR7 RS15785
gene id: 396588:TGR7_RS15785
uniprot id: B8GQJ2
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

396588:TGR7 RS14515
gene id: 396588:TGR7_RS14515
uniprot id: B8GP46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

396588:TGR7 RS10270
gene id: 396588:TGR7_RS10270
uniprot id: B8GTN7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

396588:TGR7 RS14625
gene id: 396588:TGR7_RS14625
uniprot id: B8GP68
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

396588:TGR7 RS09215
gene id: 396588:TGR7_RS09215
uniprot id: B8GSL7
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

396588:TGR7 RS10860
gene id: 396588:TGR7_RS10860
uniprot id: B8GUD0
names: Subcellular Location Annotation
messages: Cell inner membrane

396588:TGR7 RS03350
gene id: 396588:TGR7_RS03350
uniprot id: B8GMD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS08925
gene id: 396588:TGR7_RS08925
uniprot id: B8GSF7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

396588:TGR7 RS07840
gene id: 396588:TGR7_RS07840
uniprot id: B8GRU3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

396588:TGR7 RS12045
gene id: 396588:TGR7_RS12045
uniprot id: B8GLC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS00130
gene id: 396588:TGR7_RS00130
uniprot id: B8GSU5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

396588:TGR7 RS14650
gene id: 396588:TGR7_RS14650
uniprot id: B8GP73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

396588:TGR7 RS11095
gene id: 396588:TGR7_RS11095
uniprot id: B8GUH7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

396588:TGR7 RS12085
gene id: 396588:TGR7_RS12085
uniprot id: B8GLC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS04955
gene id: 396588:TGR7_RS04955
uniprot id: B8GNZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

396588:TGR7 RS10635
gene id: 396588:TGR7_RS10635
uniprot id: B8GTW1
names: Similarity
messages: Belongs to the thioredoxin family.

396588:TGR7 RS04835
gene id: 396588:TGR7_RS04835
uniprot id: B8GNW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS13190
gene id: 396588:TGR7_RS13190
uniprot id: B8GMB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

396588:TGR7 RS04890
gene id: 396588:TGR7_RS04890
uniprot id: B8GNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

396588:TGR7 RS11605
gene id: 396588:TGR7_RS11605
uniprot id: B8GV52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

396588:TGR7 RS16035
gene id: 396588:TGR7_RS16035
uniprot id: B8GQP2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

396588:TGR7 RS05325
gene id: 396588:TGR7_RS05325
uniprot id: B8GPI4
names: Similarity
messages: Belongs to the pirin family.

396588:TGR7 RS16125
gene id: 396588:TGR7_RS16125
uniprot id: B8GQR0
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

396588:TGR7 RS04525
gene id: 396588:TGR7_RS04525
uniprot id: B8GNR3
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

396588:TGR7 RS14015
gene id: 396588:TGR7_RS14015
uniprot id: B8GNH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

396588:TGR7 RS04690
gene id: 396588:TGR7_RS04690
uniprot id: B8GNU0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

396588:TGR7 RS11625
gene id: 396588:TGR7_RS11625
uniprot id: B8GV56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

396588:TGR7 RS13800
gene id: 396588:TGR7_RS13800
uniprot id: B8GN08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS13770
gene id: 396588:TGR7_RS13770
uniprot id: B8GN02
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

396588:TGR7 RS12420
gene id: 396588:TGR7_RS12420
uniprot id: B8GLJ4
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

396588:TGR7 RS02190
gene id: 396588:TGR7_RS02190
uniprot id: B8GL23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

396588:TGR7 RS11520
gene id: 396588:TGR7_RS11520
uniprot id: B8GV34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

396588:TGR7 RS08625
gene id: 396588:TGR7_RS08625
uniprot id: B8GSA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS15415
gene id: 396588:TGR7_RS15415
uniprot id: B8GPZ5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

396588:TGR7 RS13845
gene id: 396588:TGR7_RS13845
uniprot id: B8GNE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

396588:TGR7 RS01780
gene id: 396588:TGR7_RS01780
uniprot id: B8GUU9
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

396588:TGR7 RS14885
gene id: 396588:TGR7_RS14885
uniprot id: B8GPB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

396588:TGR7 RS12810
gene id: 396588:TGR7_RS12810
uniprot id: B8GM39
names: Similarity
messages: Belongs to the malate synthase family.

396588:TGR7 RS05495
gene id: 396588:TGR7_RS05495
uniprot id: B8GPL6
names: Subcellular Location Annotation
messages: Cell inner membrane

396588:TGR7 RS08045
gene id: 396588:TGR7_RS08045
uniprot id: B8GRY2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

396588:TGR7 RS06190
gene id: 396588:TGR7_RS06190
uniprot id: B8GQC8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

396588:TGR7 RS04600
gene id: 396588:TGR7_RS04600
uniprot id: B8GNS7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

396588:TGR7 RS10360
gene id: 396588:TGR7_RS10360
uniprot id: B8GTQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

396588:TGR7 RS04515
gene id: 396588:TGR7_RS04515
uniprot id: B8GND9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

396588:TGR7 RS10670
gene id: 396588:TGR7_RS10670
uniprot id: B8GTW8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

396588:TGR7 RS10990
gene id: 396588:TGR7_RS10990
uniprot id: B8GUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

396588:TGR7 RS13405
gene id: 396588:TGR7_RS13405
uniprot id: B8GMS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

396588:TGR7 RS02430
gene id: 396588:TGR7_RS02430
uniprot id: B8GL71
names: Subcellular Location Annotation
messages: Cytoplasm

396588:TGR7 RS14960
gene id: 396588:TGR7_RS14960
uniprot id: B8GPD2
names: Similarity
messages: Belongs to the fructosamine kinase family.

396588:TGR7 RS02625
gene id: 396588:TGR7_RS02625
uniprot id: B8GLA9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

396588:TGR7 RS11355
gene id: 396588:TGR7_RS11355
uniprot id: B8GUM8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

396588:TGR7 RS12135
gene id: 396588:TGR7_RS12135
uniprot id: B8GLD8
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

396588:TGR7 RS00660
gene id: 396588:TGR7_RS00660
uniprot id: B8GTH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

396588:TGR7 RS11735
gene id: 396588:TGR7_RS11735
uniprot id: B8GV74
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

396588:TGR7 RS02280
gene id: 396588:TGR7_RS02280
uniprot id: B8GL42
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

396588:TGR7 RS06065
gene id: 396588:TGR7_RS06065
uniprot id: B8GQA3
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

396588:TGR7 RS14865
gene id: 396588:TGR7_RS14865
uniprot id: B8GPB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

396588:TGR7 RS11665
gene id: 396588:TGR7_RS11665
uniprot id: B8GV64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

396588:TGR7 RS00635
gene id: 396588:TGR7_RS00635
uniprot id: B8GTH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

396588:TGR7 RS03785
gene id: 396588:TGR7_RS03785
uniprot id: B8GMM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

396588:TGR7 RS06805
gene id: 396588:TGR7_RS06805
uniprot id: B8GR23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

396588:TGR7 RS04195
gene id: 396588:TGR7_RS04195
uniprot id: B8GN79
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

396588:TGR7 RS15900
gene id: 396588:TGR7_RS15900
uniprot id: B8GQL5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

396588:TGR7 RS05015
gene id: 396588:TGR7_RS05015
uniprot id: B8GP02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

396588:TGR7 RS14855
gene id: 396588:TGR7_RS14855
uniprot id: B8GPB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

396588:TGR7 RS06270
gene id: 396588:TGR7_RS06270
uniprot id: B8GQE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

396588:TGR7 RS03825
gene id: 396588:TGR7_RS03825
uniprot id: B8GMN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

396588:TGR7 RS13365
gene id: 396588:TGR7_RS13365
uniprot id: B8GMR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

396588:TGR7 RS11745
gene id: 396588:TGR7_RS11745
uniprot id: B8GV75
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

396588:TGR7 RS07290
gene id: 396588:TGR7_RS07290
uniprot id: B8GRI3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

396588:TGR7 RS04725
gene id: 396588:TGR7_RS04725
uniprot id: B8GNU5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

396588:TGR7 RS07700
gene id: 396588:TGR7_RS07700
uniprot id: B8GRR5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

396588:TGR7 RS03015
gene id: 396588:TGR7_RS03015
uniprot id: B8GLV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

396588:TGR7 RS07755
gene id: 396588:TGR7_RS07755
uniprot id: B8GRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

396588:TGR7 RS02555
gene id: 396588:TGR7_RS02555
uniprot id: B8GL96
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

396588:TGR7 RS10740
gene id: 396588:TGR7_RS10740
uniprot id: B8GTY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

396588:TGR7 RS05435
gene id: 396588:TGR7_RS05435
uniprot id: B8GPK4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RseB family.
messages: Monomer.
messages: Periplasm

396588:TGR7 RS03940
gene id: 396588:TGR7_RS03940
uniprot id: B8GN28
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

396588:TGR7 RS14075
gene id: 396588:TGR7_RS14075
uniprot id: B8GNI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

396588:TGR7 RS03245
gene id: 396588:TGR7_RS03245
uniprot id: B8GLZ7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

396588:TGR7 RS09785
gene id: 396588:TGR7_RS09785
uniprot id: B8GT17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

396588:TGR7 RS07285
gene id: 396588:TGR7_RS07285
uniprot id: B8GRI2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

396588:TGR7 RS12345
gene id: 396588:TGR7_RS12345
uniprot id: B8GLI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

396588:TGR7 RS01140
gene id: 396588:TGR7_RS01140
uniprot id: B8GU46
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS07460
gene id: 396588:TGR7_RS07460
uniprot id: B8GRL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

396588:TGR7 RS15980
gene id: 396588:TGR7_RS15980
uniprot id: B8GQN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

396588:TGR7 RS09320
gene id: 396588:TGR7_RS09320
uniprot id: B8GSN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

396588:TGR7 RS06000
gene id: 396588:TGR7_RS06000
uniprot id: B8GQ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

396588:TGR7 RS07300
gene id: 396588:TGR7_RS07300
uniprot id: B8GRI5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

396588:TGR7 RS10180
gene id: 396588:TGR7_RS10180
uniprot id: B8GTL9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

396588:TGR7 RS04770
gene id: 396588:TGR7_RS04770
uniprot id: B8GNV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

396588:TGR7 RS04685
gene id: 396588:TGR7_RS04685
uniprot id: B8GNT9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

396588:TGR7 RS10830
gene id: 396588:TGR7_RS10830
uniprot id: B8GUC4
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

396588:TGR7 RS05470
gene id: 396588:TGR7_RS05470
uniprot id: B8GPL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

396588:TGR7 RS16270
gene id: 396588:TGR7_RS16270
uniprot id: B8GQT6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

396588:TGR7 RS10055
gene id: 396588:TGR7_RS10055
uniprot id: B8GT73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

396588:TGR7 RS04285
gene id: 396588:TGR7_RS04285
uniprot id: B8GN97
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS01740
gene id: 396588:TGR7_RS01740
uniprot id: B8GUU1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

396588:TGR7 RS07890
gene id: 396588:TGR7_RS07890
uniprot id: B8GRV3
names: Similarity
messages: Belongs to the ModE family.

396588:TGR7 RS12945
gene id: 396588:TGR7_RS12945
uniprot id: B8GM65
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS08030
gene id: 396588:TGR7_RS08030
uniprot id: B8GRX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS15835
gene id: 396588:TGR7_RS15835
uniprot id: B8GQK2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

396588:TGR7 RS06315
gene id: 396588:TGR7_RS06315
uniprot id: B8GQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

396588:TGR7 RS01300
gene id: 396588:TGR7_RS01300
uniprot id: B8GU79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

396588:TGR7 RS05460
gene id: 396588:TGR7_RS05460
uniprot id: B8GPK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

396588:TGR7 RS06240
gene id: 396588:TGR7_RS06240
uniprot id: B8GQD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS04800
gene id: 396588:TGR7_RS04800
uniprot id: B8GNW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

396588:TGR7 RS14845
gene id: 396588:TGR7_RS14845
uniprot id: B8GPB1
names: Similarity
messages: Belongs to the YicC/YloC family.

396588:TGR7 RS16605
gene id: 396588:TGR7_RS16605
uniprot id: B8GRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

396588:TGR7 RS04575
gene id: 396588:TGR7_RS04575
uniprot id: B8GNS2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

396588:TGR7 RS04935
gene id: 396588:TGR7_RS04935
uniprot id: B8GNY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

396588:TGR7 RS03715
gene id: 396588:TGR7_RS03715
uniprot id: B8GML1
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

396588:TGR7 RS09445
gene id: 396588:TGR7_RS09445
uniprot id: B8GSR2
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS05335
gene id: 396588:TGR7_RS05335
uniprot id: B8GPI6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

396588:TGR7 RS05815
gene id: 396588:TGR7_RS05815
uniprot id: B8GQ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

396588:TGR7 RS10030
gene id: 396588:TGR7_RS10030
uniprot id: B8GT68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

396588:TGR7 RS07230
gene id: 396588:TGR7_RS07230
uniprot id: B8GRH3
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS05925
gene id: 396588:TGR7_RS05925
uniprot id: B8GQ75
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

396588:TGR7 RS06245
gene id: 396588:TGR7_RS06245
uniprot id: B8GQD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS04320
gene id: 396588:TGR7_RS04320
uniprot id: B8GNA4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

396588:TGR7 RS02490
gene id: 396588:TGR7_RS02490
uniprot id: B8GL83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

396588:TGR7 RS00230
gene id: 396588:TGR7_RS00230
uniprot id: B8GT91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

396588:TGR7 RS04155
gene id: 396588:TGR7_RS04155
uniprot id: B8GN71
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

396588:TGR7 RS00535
gene id: 396588:TGR7_RS00535
uniprot id: B8GTF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

396588:TGR7 RS10225
gene id: 396588:TGR7_RS10225
uniprot id: B8GTM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

396588:TGR7 RS04740
gene id: 396588:TGR7_RS04740
uniprot id: B8GNU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

396588:TGR7 RS05975
gene id: 396588:TGR7_RS05975
uniprot id: B8GQ85
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

396588:TGR7 RS05505
gene id: 396588:TGR7_RS05505
uniprot id: B8GPL8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

396588:TGR7 RS07595
gene id: 396588:TGR7_RS07595
uniprot id: B8GRP4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

396588:TGR7 RS04175
gene id: 396588:TGR7_RS04175
uniprot id: B8GN75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

396588:TGR7 RS00915
gene id: 396588:TGR7_RS00915
uniprot id: B8GU01
names: Similarity
messages: Belongs to the asparagine synthetase family.

396588:TGR7 RS05635
gene id: 396588:TGR7_RS05635
uniprot id: B8GPP4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS13270
gene id: 396588:TGR7_RS13270
uniprot id: B8GMQ0
names: Similarity
messages: Belongs to the universal stress protein A family.

396588:TGR7 RS06380
gene id: 396588:TGR7_RS06380
uniprot id: B8GQG6
names: Similarity
messages: Belongs to the HypD family.

396588:TGR7 RS11515
gene id: 396588:TGR7_RS11515
uniprot id: B8GV33
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

396588:TGR7 RS03740
gene id: 396588:TGR7_RS03740
uniprot id: B8GML6
names: Similarity
messages: Belongs to the UPF0102 family.

396588:TGR7 RS11770
gene id: 396588:TGR7_RS11770
uniprot id: B8GV80
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

396588:TGR7 RS04815
gene id: 396588:TGR7_RS04815
uniprot id: B8GNW4
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

396588:TGR7 RS15125
gene id: 396588:TGR7_RS15125
uniprot id: B8GPU0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

396588:TGR7 RS15570
gene id: 396588:TGR7_RS15570
uniprot id: B8GQ25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

396588:TGR7 RS12720
gene id: 396588:TGR7_RS12720
uniprot id: B8GM21
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS02615
gene id: 396588:TGR7_RS02615
uniprot id: B8GLA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

396588:TGR7 RS04010
gene id: 396588:TGR7_RS04010
uniprot id: B8GN42
names: Similarity
messages: Belongs to the P(II) protein family.

396588:TGR7 RS06280
gene id: 396588:TGR7_RS06280
uniprot id: B8GQE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

396588:TGR7 RS10945
gene id: 396588:TGR7_RS10945
uniprot id: B8GUE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

396588:TGR7 RS14640
gene id: 396588:TGR7_RS14640
uniprot id: B8GP71
names: Similarity
messages: Belongs to the GSP E family.

396588:TGR7 RS05935
gene id: 396588:TGR7_RS05935
uniprot id: B8GQ77
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

396588:TGR7 RS07735
gene id: 396588:TGR7_RS07735
uniprot id: B8GRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

396588:TGR7 RS09875
gene id: 396588:TGR7_RS09875
uniprot id: B8GT35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

396588:TGR7 RS13390
gene id: 396588:TGR7_RS13390
uniprot id: B8GMS3
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS16640
gene id: 396588:TGR7_RS16640
uniprot id: B8GRD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

396588:TGR7 RS15120
gene id: 396588:TGR7_RS15120
uniprot id: B8GPT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

396588:TGR7 RS04960
gene id: 396588:TGR7_RS04960
uniprot id: B8GNZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

396588:TGR7 RS04590
gene id: 396588:TGR7_RS04590
uniprot id: B8GNS5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

396588:TGR7 RS02285
gene id: 396588:TGR7_RS02285
uniprot id: B8GL43
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

396588:TGR7 RS02580
gene id: 396588:TGR7_RS02580
uniprot id: B8GLA1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

396588:TGR7 RS14475
gene id: 396588:TGR7_RS14475
uniprot id: B8GP38
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

396588:TGR7 RS05790
gene id: 396588:TGR7_RS05790
uniprot id: B8GPS6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

396588:TGR7 RS03575
gene id: 396588:TGR7_RS03575
uniprot id: B8GMI3
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

396588:TGR7 RS05520
gene id: 396588:TGR7_RS05520
uniprot id: B8GPM1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

396588:TGR7 RS13185
gene id: 396588:TGR7_RS13185
uniprot id: B8GMB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

396588:TGR7 RS14520
gene id: 396588:TGR7_RS14520
uniprot id: B8GP47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

396588:TGR7 RS13900
gene id: 396588:TGR7_RS13900
uniprot id: B8GNF3
names: Subcellular Location Annotation
messages: Nucleus

396588:TGR7 RS04085
gene id: 396588:TGR7_RS04085
uniprot id: B8GN57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

396588:TGR7 RS01095
gene id: 396588:TGR7_RS01095
uniprot id: B8GU37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

396588:TGR7 RS01420
gene id: 396588:TGR7_RS01420
uniprot id: B8GUA3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS01245
gene id: 396588:TGR7_RS01245
uniprot id: B8GU67
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

396588:TGR7 RS01775
gene id: 396588:TGR7_RS01775
uniprot id: B8GUU8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

396588:TGR7 RS15620
gene id: 396588:TGR7_RS15620
uniprot id: B8GQ35
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS08900
gene id: 396588:TGR7_RS08900
uniprot id: B8GSF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

396588:TGR7 RS13205
gene id: 396588:TGR7_RS13205
uniprot id: B8GMB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

396588:TGR7 RS01090
gene id: 396588:TGR7_RS01090
uniprot id: B8GU36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

396588:TGR7 RS01055
gene id: 396588:TGR7_RS01055
uniprot id: B8GU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

396588:TGR7 RS13140
gene id: 396588:TGR7_RS13140
uniprot id: B8GMA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

396588:TGR7 RS00475
gene id: 396588:TGR7_RS00475
uniprot id: B8GTE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

396588:TGR7 RS16240
gene id: 396588:TGR7_RS16240
uniprot id: B8GQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

396588:TGR7 RS13955
gene id: 396588:TGR7_RS13955
uniprot id: B8GNG4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

396588:TGR7 RS04985
gene id: 396588:TGR7_RS04985
uniprot id: B8GNZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

396588:TGR7 RS13815
gene id: 396588:TGR7_RS13815
uniprot id: B8GN11
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

396588:TGR7 RS12750
gene id: 396588:TGR7_RS12750
uniprot id: B8GM27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

396588:TGR7 RS05865
gene id: 396588:TGR7_RS05865
uniprot id: B8GQ63
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

396588:TGR7 RS07620
gene id: 396588:TGR7_RS07620
uniprot id: B8GRP9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

396588:TGR7 RS07985
gene id: 396588:TGR7_RS07985
uniprot id: B8GRX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

396588:TGR7 RS02670
gene id: 396588:TGR7_RS02670
uniprot id: B8GLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

396588:TGR7 RS09565
gene id: 396588:TGR7_RS09565
uniprot id: B8GSX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

396588:TGR7 RS06375
gene id: 396588:TGR7_RS06375
uniprot id: B8GQG5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

396588:TGR7 RS14480
gene id: 396588:TGR7_RS14480
uniprot id: B8GP39
names: Similarity
messages: Belongs to the SAICAR synthetase family.

396588:TGR7 RS15655
gene id: 396588:TGR7_RS15655
uniprot id: B8GQ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS13275
gene id: 396588:TGR7_RS13275
uniprot id: B8GMQ1
names: Similarity
messages: Belongs to the UPF0276 family.

396588:TGR7 RS05175
gene id: 396588:TGR7_RS05175
uniprot id: B8GP33
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

396588:TGR7 RS01755
gene id: 396588:TGR7_RS01755
uniprot id: B8GUU4
names: Similarity
messages: Belongs to the thioredoxin family.

396588:TGR7 RS16570
gene id: 396588:TGR7_RS16570
uniprot id: B8GRB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

396588:TGR7 RS05170
gene id: 396588:TGR7_RS05170
uniprot id: B8GP32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

396588:TGR7 RS04110
gene id: 396588:TGR7_RS04110
uniprot id: B8GN62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

396588:TGR7 RS10380
gene id: 396588:TGR7_RS10380
uniprot id: B8GTQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

396588:TGR7 RS03000
gene id: 396588:TGR7_RS03000
uniprot id: B8GLU7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

396588:TGR7 RS02180
gene id: 396588:TGR7_RS02180
uniprot id: B8GL21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

396588:TGR7 RS00440
gene id: 396588:TGR7_RS00440
uniprot id: B8GTD3
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

396588:TGR7 RS04645
gene id: 396588:TGR7_RS04645
uniprot id: B8GNT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

396588:TGR7 RS07835
gene id: 396588:TGR7_RS07835
uniprot id: B8GRU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

396588:TGR7 RS01330
gene id: 396588:TGR7_RS01330
uniprot id: B8GU85
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

396588:TGR7 RS02375
gene id: 396588:TGR7_RS02375
uniprot id: B8GL60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

396588:TGR7 RS07295
gene id: 396588:TGR7_RS07295
uniprot id: B8GRI4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

396588:TGR7 RS16345
gene id: 396588:TGR7_RS16345
uniprot id: B8GR72
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS01155
gene id: 396588:TGR7_RS01155
uniprot id: B8GU49
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

396588:TGR7 RS13620
gene id: 396588:TGR7_RS13620
uniprot id: B8GMX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

396588:TGR7 RS01080
gene id: 396588:TGR7_RS01080
uniprot id: B8GU34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

396588:TGR7 RS13340
gene id: 396588:TGR7_RS13340
uniprot id: B8GMR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

396588:TGR7 RS11170
gene id: 396588:TGR7_RS11170
uniprot id: B8GUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

396588:TGR7 RS16820
gene id: 396588:TGR7_RS16820
uniprot id: B8GVA2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

396588:TGR7 RS07430
gene id: 396588:TGR7_RS07430
uniprot id: B8GRL1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

396588:TGR7 RS04900
gene id: 396588:TGR7_RS04900
uniprot id: B8GNY1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

396588:TGR7 RS00585
gene id: 396588:TGR7_RS00585
uniprot id: B8GTG1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

396588:TGR7 RS16100
gene id: 396588:TGR7_RS16100
uniprot id: B8GQQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

396588:TGR7 RS11395
gene id: 396588:TGR7_RS11395
uniprot id: B8GV10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

396588:TGR7 RS10645
gene id: 396588:TGR7_RS10645
uniprot id: B8GTW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

396588:TGR7 RS01085
gene id: 396588:TGR7_RS01085
uniprot id: B8GU35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

396588:TGR7 RS10915
gene id: 396588:TGR7_RS10915
uniprot id: B8GUE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

396588:TGR7 RS12525
gene id: 396588:TGR7_RS12525
uniprot id: B8GLL4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

396588:TGR7 RS01325
gene id: 396588:TGR7_RS01325
uniprot id: B8GU84
names: Similarity
messages: Belongs to the AlaDH/PNT family.

396588:TGR7 RS09305
gene id: 396588:TGR7_RS09305
uniprot id: B8GSN5
names: Similarity
messages: Belongs to the peptidase M17 family.

396588:TGR7 RS03795
gene id: 396588:TGR7_RS03795
uniprot id: B8GMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

396588:TGR7 RS01735
gene id: 396588:TGR7_RS01735
uniprot id: B8GUU0
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

396588:TGR7 RS00015
gene id: 396588:TGR7_RS00015
uniprot id: B8GSS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

396588:TGR7 RS03100
gene id: 396588:TGR7_RS03100
uniprot id: B8GLW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

396588:TGR7 RS00415
gene id: 396588:TGR7_RS00415
uniprot id: B8GTC8
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

396588:TGR7 RS05510
gene id: 396588:TGR7_RS05510
uniprot id: B8GPL9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

396588:TGR7 RS06385
gene id: 396588:TGR7_RS06385
uniprot id: B8GQG7
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

396588:TGR7 RS01075
gene id: 396588:TGR7_RS01075
uniprot id: B8GU33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS12935
gene id: 396588:TGR7_RS12935
uniprot id: B8GM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

396588:TGR7 RS09635
gene id: 396588:TGR7_RS09635
uniprot id: B8GSY7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

396588:TGR7 RS04910
gene id: 396588:TGR7_RS04910
uniprot id: B8GNY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

396588:TGR7 RS13145
gene id: 396588:TGR7_RS13145
uniprot id: B8GMA3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

396588:TGR7 RS07760
gene id: 396588:TGR7_RS07760
uniprot id: B8GRS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

396588:TGR7 RS03510
gene id: 396588:TGR7_RS03510
uniprot id: B8GMH0
names: Similarity
messages: Belongs to the BolA/IbaG family.

396588:TGR7 RS07370
gene id: 396588:TGR7_RS07370
uniprot id: B8GRJ9
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS06870
gene id: 396588:TGR7_RS06870
uniprot id: B8GR36
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS15185
gene id: 396588:TGR7_RS15185
uniprot id: B8GPV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

396588:TGR7 RS11655
gene id: 396588:TGR7_RS11655
uniprot id: B8GV62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

396588:TGR7 RS09210
gene id: 396588:TGR7_RS09210
uniprot id: B8GSL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

396588:TGR7 RS13170
gene id: 396588:TGR7_RS13170
uniprot id: B8GMA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

396588:TGR7 RS07445
gene id: 396588:TGR7_RS07445
uniprot id: B8GRL4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

396588:TGR7 RS01150
gene id: 396588:TGR7_RS01150
uniprot id: B8GU48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS09145
gene id: 396588:TGR7_RS09145
uniprot id: B8GSK3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

396588:TGR7 RS16575
gene id: 396588:TGR7_RS16575
uniprot id: B8GRB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

396588:TGR7 RS04805
gene id: 396588:TGR7_RS04805
uniprot id: B8GNW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

396588:TGR7 RS01040
gene id: 396588:TGR7_RS01040
uniprot id: B8GU26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS07820
gene id: 396588:TGR7_RS07820
uniprot id: B8GRT9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

396588:TGR7 RS02530
gene id: 396588:TGR7_RS02530
uniprot id: B8GL91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

396588:TGR7 RS02545
gene id: 396588:TGR7_RS02545
uniprot id: B8GL94
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

396588:TGR7 RS10345
gene id: 396588:TGR7_RS10345
uniprot id: B8GTQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

396588:TGR7 RS10700
gene id: 396588:TGR7_RS10700
uniprot id: B8GTX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

396588:TGR7 RS10440
gene id: 396588:TGR7_RS10440
uniprot id: B8GTR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

396588:TGR7 RS01770
gene id: 396588:TGR7_RS01770
uniprot id: B8GUU7
names: Similarity
messages: Belongs to the GARS family.

396588:TGR7 RS13615
gene id: 396588:TGR7_RS13615
uniprot id: B8GMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

396588:TGR7 RS03140
gene id: 396588:TGR7_RS03140
uniprot id: B8GLX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

396588:TGR7 RS06655
gene id: 396588:TGR7_RS06655
uniprot id: B8GQZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

396588:TGR7 RS05375
gene id: 396588:TGR7_RS05375
uniprot id: B8GPJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

396588:TGR7 RS04945
gene id: 396588:TGR7_RS04945
uniprot id: B8GNY9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

396588:TGR7 RS07695
gene id: 396588:TGR7_RS07695
uniprot id: B8GRR4
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

396588:TGR7 RS07730
gene id: 396588:TGR7_RS07730
uniprot id: B8GRS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

396588:TGR7 RS00165
gene id: 396588:TGR7_RS00165
uniprot id: B8GSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

396588:TGR7 RS14645
gene id: 396588:TGR7_RS14645
uniprot id: B8GP72
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

396588:TGR7 RS07885
gene id: 396588:TGR7_RS07885
uniprot id: B8GRV2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

396588:TGR7 RS05485
gene id: 396588:TGR7_RS05485
uniprot id: B8GPL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

396588:TGR7 RS13890
gene id: 396588:TGR7_RS13890
uniprot id: B8GNF1
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

396588:TGR7 RS15475
gene id: 396588:TGR7_RS15475
uniprot id: B8GQ06
names: Similarity
messages: Belongs to the creatininase superfamily.

396588:TGR7 RS13335
gene id: 396588:TGR7_RS13335
uniprot id: B8GMR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

396588:TGR7 RS13395
gene id: 396588:TGR7_RS13395
uniprot id: B8GMS4
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS08440
gene id: 396588:TGR7_RS08440
uniprot id: B8GS62
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS10555
gene id: 396588:TGR7_RS10555
uniprot id: B8GTU5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

396588:TGR7 RS06865
gene id: 396588:TGR7_RS06865
uniprot id: B8GR35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

396588:TGR7 RS09975
gene id: 396588:TGR7_RS09975
uniprot id: B8GT58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

396588:TGR7 RS04455
gene id: 396588:TGR7_RS04455
uniprot id: B8GND0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

396588:TGR7 RS05880
gene id: 396588:TGR7_RS05880
uniprot id: B8GQ66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

396588:TGR7 RS10215
gene id: 396588:TGR7_RS10215
uniprot id: B8GTM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS04905
gene id: 396588:TGR7_RS04905
uniprot id: B8GNY2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

396588:TGR7 RS16020
gene id: 396588:TGR7_RS16020
uniprot id: B8GQN9
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

396588:TGR7 RS11180
gene id: 396588:TGR7_RS11180
uniprot id: B8GUJ3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

396588:TGR7 RS03800
gene id: 396588:TGR7_RS03800
uniprot id: B8GMM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that is essential for cell division.

396588:TGR7 RS12220
gene id: 396588:TGR7_RS12220
uniprot id: B8GLF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

396588:TGR7 RS15670
gene id: 396588:TGR7_RS15670
uniprot id: B8GQ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cytoplasm
messages: Homodimer or homotetramer.

396588:TGR7 RS08035
gene id: 396588:TGR7_RS08035
uniprot id: B8GRY0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

396588:TGR7 RS05545
gene id: 396588:TGR7_RS05545
uniprot id: B8GPM6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

396588:TGR7 RS12175
gene id: 396588:TGR7_RS12175
uniprot id: B8GLE6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

396588:TGR7 RS09205
gene id: 396588:TGR7_RS09205
uniprot id: B8GSL5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

396588:TGR7 RS01335
gene id: 396588:TGR7_RS01335
uniprot id: B8GU86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

396588:TGR7 RS11005
gene id: 396588:TGR7_RS11005
uniprot id: B8GUF9
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

396588:TGR7 RS11210
gene id: 396588:TGR7_RS11210
uniprot id: B8GUJ9
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

396588:TGR7 RS15650
gene id: 396588:TGR7_RS15650
uniprot id: B8GQ41
names: Similarity
messages: Belongs to the P(II) protein family.

396588:TGR7 RS04360
gene id: 396588:TGR7_RS04360
uniprot id: B8GNB2
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

396588:TGR7 RS04965
gene id: 396588:TGR7_RS04965
uniprot id: B8GNZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

396588:TGR7 RS09465
gene id: 396588:TGR7_RS09465
uniprot id: B8GSR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

396588:TGR7 RS07275
gene id: 396588:TGR7_RS07275
uniprot id: B8GRI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS00965
gene id: 396588:TGR7_RS00965
uniprot id: B8GU11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

396588:TGR7 RS00220
gene id: 396588:TGR7_RS00220
uniprot id: B8GT89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS12375
gene id: 396588:TGR7_RS12375
uniprot id: B8GLI6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

396588:TGR7 RS15905
gene id: 396588:TGR7_RS15905
uniprot id: B8GQL6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

396588:TGR7 RS07680
gene id: 396588:TGR7_RS07680
uniprot id: B8GRR1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS07350
gene id: 396588:TGR7_RS07350
uniprot id: B8GRJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

396588:TGR7 RS04520
gene id: 396588:TGR7_RS04520
uniprot id: B8GNE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

396588:TGR7 RS16025
gene id: 396588:TGR7_RS16025
uniprot id: B8GQP0
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

396588:TGR7 RS07415
gene id: 396588:TGR7_RS07415
uniprot id: B8GRK8
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS02680
gene id: 396588:TGR7_RS02680
uniprot id: B8GLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

396588:TGR7 RS15065
gene id: 396588:TGR7_RS15065
uniprot id: B8GPF4
names: Similarity
messages: Belongs to the SCO1/2 family.

396588:TGR7 RS09510
gene id: 396588:TGR7_RS09510
uniprot id: B8GSW4
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

396588:TGR7 RS01605
gene id: 396588:TGR7_RS01605
uniprot id: B8GUR3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

396588:TGR7 RS02200
gene id: 396588:TGR7_RS02200
uniprot id: B8GL25
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

396588:TGR7 RS15435
gene id: 396588:TGR7_RS15435
uniprot id: B8GPZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

396588:TGR7 RS00605
gene id: 396588:TGR7_RS00605
uniprot id: B8GTG5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

396588:TGR7 RS09220
gene id: 396588:TGR7_RS09220
uniprot id: B8GSL8
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

396588:TGR7 RS00905
gene id: 396588:TGR7_RS00905
uniprot id: B8GTZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

396588:TGR7 RS11295
gene id: 396588:TGR7_RS11295
uniprot id: B8GUL6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

396588:TGR7 RS00035
gene id: 396588:TGR7_RS00035
uniprot id: B8GSS7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

396588:TGR7 RS14080
gene id: 396588:TGR7_RS14080
uniprot id: B8GNI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

396588:TGR7 RS13330
gene id: 396588:TGR7_RS13330
uniprot id: B8GMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS06690
gene id: 396588:TGR7_RS06690
uniprot id: B8GR00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

396588:TGR7 RS10790
gene id: 396588:TGR7_RS10790
uniprot id: B8GUB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

396588:TGR7 RS04260
gene id: 396588:TGR7_RS04260
uniprot id: B8GN92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

396588:TGR7 RS16135
gene id: 396588:TGR7_RS16135
uniprot id: B8GQR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

396588:TGR7 RS14895
gene id: 396588:TGR7_RS14895
uniprot id: B8GPC1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

396588:TGR7 RS14880
gene id: 396588:TGR7_RS14880
uniprot id: B8GPB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

396588:TGR7 RS06705
gene id: 396588:TGR7_RS06705
uniprot id: B8GR03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

396588:TGR7 RS01290
gene id: 396588:TGR7_RS01290
uniprot id: B8GU77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

396588:TGR7 RS10765
gene id: 396588:TGR7_RS10765
uniprot id: B8GUB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS10165
gene id: 396588:TGR7_RS10165
uniprot id: B8GTL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

396588:TGR7 RS12365
gene id: 396588:TGR7_RS12365
uniprot id: B8GLI4
names: Similarity
messages: Belongs to the asparagine synthetase family.

396588:TGR7 RS00445
gene id: 396588:TGR7_RS00445
uniprot id: B8GTD4
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS06490
gene id: 396588:TGR7_RS06490
uniprot id: B8GQW2
names: PTM
messages: Binds 1 heme group per subunit.

396588:TGR7 RS10190
gene id: 396588:TGR7_RS10190
uniprot id: B8GTM1
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

396588:TGR7 RS06990
gene id: 396588:TGR7_RS06990
uniprot id: B8GR59
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

396588:TGR7 RS15565
gene id: 396588:TGR7_RS15565
uniprot id: B8GQ24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

396588:TGR7 RS06365
gene id: 396588:TGR7_RS06365
uniprot id: B8GQG3
names: Similarity
messages: Belongs to the HupF/HypC family.

396588:TGR7 RS03620
gene id: 396588:TGR7_RS03620
uniprot id: B8GMJ2
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS11545
gene id: 396588:TGR7_RS11545
uniprot id: B8GV40
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

396588:TGR7 RS05150
gene id: 396588:TGR7_RS05150
uniprot id: B8GP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

396588:TGR7 RS02215
gene id: 396588:TGR7_RS02215
uniprot id: B8GL28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

396588:TGR7 RS10960
gene id: 396588:TGR7_RS10960
uniprot id: B8GUF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

396588:TGR7 RS07845
gene id: 396588:TGR7_RS07845
uniprot id: B8GRU4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

396588:TGR7 RS08450
gene id: 396588:TGR7_RS08450
uniprot id: B8GS64
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS15485
gene id: 396588:TGR7_RS15485
uniprot id: B8GQ08
names: Caution
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcriptional regulator.

396588:TGR7 RS02290
gene id: 396588:TGR7_RS02290
uniprot id: B8GL44
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

396588:TGR7 RS03675
gene id: 396588:TGR7_RS03675
uniprot id: B8GMK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

396588:TGR7 RS02210
gene id: 396588:TGR7_RS02210
uniprot id: B8GL27
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS15560
gene id: 396588:TGR7_RS15560
uniprot id: B8GQ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

396588:TGR7 RS09570
gene id: 396588:TGR7_RS09570
uniprot id: B8GSX4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

396588:TGR7 RS10015
gene id: 396588:TGR7_RS10015
uniprot id: B8GT65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

396588:TGR7 RS09225
gene id: 396588:TGR7_RS09225
uniprot id: B8GSL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS15060
gene id: 396588:TGR7_RS15060
uniprot id: B8GPF3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

396588:TGR7 RS00700
gene id: 396588:TGR7_RS00700
uniprot id: B8GTI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

396588:TGR7 RS02170
gene id: 396588:TGR7_RS02170
uniprot id: B8GL19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

396588:TGR7 RS12335
gene id: 396588:TGR7_RS12335
uniprot id: B8GLH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

396588:TGR7 RS06160
gene id: 396588:TGR7_RS06160
uniprot id: B8GQC2
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

396588:TGR7 RS05760
gene id: 396588:TGR7_RS05760
uniprot id: B8GPS0
names: Similarity
messages: Belongs to the ArsC family.

396588:TGR7 RS15580
gene id: 396588:TGR7_RS15580
uniprot id: B8GQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

396588:TGR7 RS05870
gene id: 396588:TGR7_RS05870
uniprot id: B8GQ64
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

396588:TGR7 RS00575
gene id: 396588:TGR7_RS00575
uniprot id: B8GTF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

396588:TGR7 RS00390
gene id: 396588:TGR7_RS00390
uniprot id: B8GTC3
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

396588:TGR7 RS12390
gene id: 396588:TGR7_RS12390
uniprot id: B8GLI9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

396588:TGR7 RS08990
gene id: 396588:TGR7_RS08990
uniprot id: B8GSH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

396588:TGR7 RS04430
gene id: 396588:TGR7_RS04430
uniprot id: B8GNC5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

396588:TGR7 RS13590
gene id: 396588:TGR7_RS13590
uniprot id: B8GMW6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

396588:TGR7 RS07465
gene id: 396588:TGR7_RS07465
uniprot id: B8GRL8
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

396588:TGR7 RS06300
gene id: 396588:TGR7_RS06300
uniprot id: B8GQF0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS07880
gene id: 396588:TGR7_RS07880
uniprot id: B8GRV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

396588:TGR7 RS10255
gene id: 396588:TGR7_RS10255
uniprot id: B8GTN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS08765
gene id: 396588:TGR7_RS08765
uniprot id: B8GSC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS09720
gene id: 396588:TGR7_RS09720
uniprot id: B8GT04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

396588:TGR7 RS11155
gene id: 396588:TGR7_RS11155
uniprot id: B8GUI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

396588:TGR7 RS07305
gene id: 396588:TGR7_RS07305
uniprot id: B8GRI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

396588:TGR7 RS00940
gene id: 396588:TGR7_RS00940
uniprot id: B8GU06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

396588:TGR7 RS10135
gene id: 396588:TGR7_RS10135
uniprot id: B8GTL0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

396588:TGR7 RS16560
gene id: 396588:TGR7_RS16560
uniprot id: B8GRB5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS06885
gene id: 396588:TGR7_RS06885
uniprot id: B8GR39
names: Similarity
messages: Belongs to the UPF0434 family.

396588:TGR7 RS15640
gene id: 396588:TGR7_RS15640
uniprot id: B8GQ39
names: Function
names: Similarity
messages: Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
messages: Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia.

396588:TGR7 RS09710
gene id: 396588:TGR7_RS09710
uniprot id: B8GT02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

396588:TGR7 RS09700
gene id: 396588:TGR7_RS09700
uniprot id: B8GT00
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

396588:TGR7 RS01425
gene id: 396588:TGR7_RS01425
uniprot id: B8GUA4
names: Similarity
messages: Belongs to the pirin family.

396588:TGR7 RS04020
gene id: 396588:TGR7_RS04020
uniprot id: B8GN44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

396588:TGR7 RS11650
gene id: 396588:TGR7_RS11650
uniprot id: B8GV61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

396588:TGR7 RS10755
gene id: 396588:TGR7_RS10755
uniprot id: B8GUA9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

396588:TGR7 RS13370
gene id: 396588:TGR7_RS13370
uniprot id: B8GMR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

396588:TGR7 RS12100
gene id: 396588:TGR7_RS12100
uniprot id: B8GLD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

396588:TGR7 RS07075
gene id: 396588:TGR7_RS07075
uniprot id: B8GRE2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

396588:TGR7 RS15550
gene id: 396588:TGR7_RS15550
uniprot id: B8GQ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

396588:TGR7 RS11670
gene id: 396588:TGR7_RS11670
uniprot id: B8GV65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

396588:TGR7 RS11350
gene id: 396588:TGR7_RS11350
uniprot id: B8GUM7
names: Similarity
messages: Belongs to the peptidase U62 family.

396588:TGR7 RS03460
gene id: 396588:TGR7_RS03460
uniprot id: B8GMG0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS15945
gene id: 396588:TGR7_RS15945
uniprot id: B8GQM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

396588:TGR7 RS14085
gene id: 396588:TGR7_RS14085
uniprot id: B8GNI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS14935
gene id: 396588:TGR7_RS14935
uniprot id: B8GPC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

396588:TGR7 RS06455
gene id: 396588:TGR7_RS06455
uniprot id: B8GQV6
names: Similarity
messages: Belongs to the aspartokinase family.

396588:TGR7 RS06220
gene id: 396588:TGR7_RS06220
uniprot id: B8GQD4
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS11510
gene id: 396588:TGR7_RS11510
uniprot id: B8GV32
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

396588:TGR7 RS14040
gene id: 396588:TGR7_RS14040
uniprot id: B8GNI0
names: Similarity
messages: Belongs to the TrpC family.

396588:TGR7 RS14010
gene id: 396588:TGR7_RS14010
uniprot id: B8GNH4
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

396588:TGR7 RS05900
gene id: 396588:TGR7_RS05900
uniprot id: B8GQ70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

396588:TGR7 RS10875
gene id: 396588:TGR7_RS10875
uniprot id: B8GUD3
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

396588:TGR7 RS12380
gene id: 396588:TGR7_RS12380
uniprot id: B8GLI7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

396588:TGR7 RS03840
gene id: 396588:TGR7_RS03840
uniprot id: B8GMN6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

396588:TGR7 RS09255
gene id: 396588:TGR7_RS09255
uniprot id: B8GSM5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

396588:TGR7 RS09160
gene id: 396588:TGR7_RS09160
uniprot id: B8GSK6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

396588:TGR7 RS01480
gene id: 396588:TGR7_RS01480
uniprot id: B8GUN8
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

396588:TGR7 RS11495
gene id: 396588:TGR7_RS11495
uniprot id: B8GV29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

396588:TGR7 RS15320
gene id: 396588:TGR7_RS15320
uniprot id: B8GPX6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS06325
gene id: 396588:TGR7_RS06325
uniprot id: B8GQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

396588:TGR7 RS15105
gene id: 396588:TGR7_RS15105
uniprot id: B8GPT6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

396588:TGR7 RS04265
gene id: 396588:TGR7_RS04265
uniprot id: B8GN93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

396588:TGR7 RS11630
gene id: 396588:TGR7_RS11630
uniprot id: B8GV57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

396588:TGR7 RS01315
gene id: 396588:TGR7_RS01315
uniprot id: B8GU82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

396588:TGR7 RS07495
gene id: 396588:TGR7_RS07495
uniprot id: B8GRM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

396588:TGR7 RS08060
gene id: 396588:TGR7_RS08060
uniprot id: B8GRY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

396588:TGR7 RS11570
gene id: 396588:TGR7_RS11570
uniprot id: B8GV45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

396588:TGR7 RS05930
gene id: 396588:TGR7_RS05930
uniprot id: B8GQ76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

396588:TGR7 RS05920
gene id: 396588:TGR7_RS05920
uniprot id: B8GQ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

396588:TGR7 RS13665
gene id: 396588:TGR7_RS13665
uniprot id: B8GMY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

396588:TGR7 RS10800
gene id: 396588:TGR7_RS10800
uniprot id: B8GUB8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

396588:TGR7 RS04950
gene id: 396588:TGR7_RS04950
uniprot id: B8GNZ0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

396588:TGR7 RS15575
gene id: 396588:TGR7_RS15575
uniprot id: B8GQ26
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

396588:TGR7 RS02640
gene id: 396588:TGR7_RS02640
uniprot id: B8GLB1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

396588:TGR7 RS12130
gene id: 396588:TGR7_RS12130
uniprot id: B8GLD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

396588:TGR7 RS13235
gene id: 396588:TGR7_RS13235
uniprot id: B8GMC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

396588:TGR7 RS01570
gene id: 396588:TGR7_RS01570
uniprot id: B8GUQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

396588:TGR7 RS04345
gene id: 396588:TGR7_RS04345
uniprot id: B8GNA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

396588:TGR7 RS10950
gene id: 396588:TGR7_RS10950
uniprot id: B8GUE8
names: Similarity
messages: Belongs to the DsrF/TusC family.

396588:TGR7 RS01830
gene id: 396588:TGR7_RS01830
uniprot id: B8GUV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

396588:TGR7 RS03090
gene id: 396588:TGR7_RS03090
uniprot id: B8GLW5
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS16595
gene id: 396588:TGR7_RS16595
uniprot id: B8GRC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

396588:TGR7 RS13220
gene id: 396588:TGR7_RS13220
uniprot id: B8GMB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

396588:TGR7 RS05980
gene id: 396588:TGR7_RS05980
uniprot id: B8GQ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

396588:TGR7 RS14600
gene id: 396588:TGR7_RS14600
uniprot id: B8GP63
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

396588:TGR7 RS16200
gene id: 396588:TGR7_RS16200
uniprot id: B8GQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

396588:TGR7 RS12415
gene id: 396588:TGR7_RS12415
uniprot id: B8GLJ3
names: Similarity
messages: Belongs to the UPF0111 family.

396588:TGR7 RS01100
gene id: 396588:TGR7_RS01100
uniprot id: B8GU38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

396588:TGR7 RS16030
gene id: 396588:TGR7_RS16030
uniprot id: B8GQP1
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

396588:TGR7 RS13350
gene id: 396588:TGR7_RS13350
uniprot id: B8GMR5
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS02265
gene id: 396588:TGR7_RS02265
uniprot id: B8GL39
names: Similarity
messages: Belongs to the GSP E family.

396588:TGR7 RS15805
gene id: 396588:TGR7_RS15805
uniprot id: B8GQJ6
names: Similarity
messages: Belongs to the peptidase S24 family.

396588:TGR7 RS05845
gene id: 396588:TGR7_RS05845
uniprot id: B8GQ59
names: Similarity
messages: Belongs to the skp family.

396588:TGR7 RS06775
gene id: 396588:TGR7_RS06775
uniprot id: B8GR17
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

396588:TGR7 RS09180
gene id: 396588:TGR7_RS09180
uniprot id: B8GSL0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

396588:TGR7 RS16080
gene id: 396588:TGR7_RS16080
uniprot id: B8GQQ0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

396588:TGR7 RS10105
gene id: 396588:TGR7_RS10105
uniprot id: B8GT83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

396588:TGR7 RS06105
gene id: 396588:TGR7_RS06105
uniprot id: B8GQB1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

396588:TGR7 RS10695
gene id: 396588:TGR7_RS10695
uniprot id: B8GTX3
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS01115
gene id: 396588:TGR7_RS01115
uniprot id: B8GU41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

396588:TGR7 RS00505
gene id: 396588:TGR7_RS00505
uniprot id: B8GTE5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS15465
gene id: 396588:TGR7_RS15465
uniprot id: B8GQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

396588:TGR7 RS16260
gene id: 396588:TGR7_RS16260
uniprot id: B8GQT4
names: Similarity
messages: Belongs to the phosphoribulokinase family.

396588:TGR7 RS00395
gene id: 396588:TGR7_RS00395
uniprot id: B8GTC4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

396588:TGR7 RS14805
gene id: 396588:TGR7_RS14805
uniprot id: B8GPA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

396588:TGR7 RS12270
gene id: 396588:TGR7_RS12270
uniprot id: B8GLG5
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

396588:TGR7 RS03375
gene id: 396588:TGR7_RS03375
uniprot id: B8GME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

396588:TGR7 RS15140
gene id: 396588:TGR7_RS15140
uniprot id: B8GPU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS02550
gene id: 396588:TGR7_RS02550
uniprot id: B8GL95
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

396588:TGR7 RS14995
gene id: 396588:TGR7_RS14995
uniprot id: B8GPD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

396588:TGR7 RS14065
gene id: 396588:TGR7_RS14065
uniprot id: B8GNI5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

396588:TGR7 RS15430
gene id: 396588:TGR7_RS15430
uniprot id: B8GPZ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

396588:TGR7 RS09230
gene id: 396588:TGR7_RS09230
uniprot id: B8GSM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

396588:TGR7 RS06095
gene id: 396588:TGR7_RS06095
uniprot id: B8GQA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

396588:TGR7 RS16130
gene id: 396588:TGR7_RS16130
uniprot id: B8GQR1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

396588:TGR7 RS14440
gene id: 396588:TGR7_RS14440
uniprot id: B8GNR0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

396588:TGR7 RS13550
gene id: 396588:TGR7_RS13550
uniprot id: B8GMV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

396588:TGR7 RS06035
gene id: 396588:TGR7_RS06035
uniprot id: B8GQ96
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

396588:TGR7 RS01030
gene id: 396588:TGR7_RS01030
uniprot id: B8GU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

396588:TGR7 RS10540
gene id: 396588:TGR7_RS10540
uniprot id: B8GTU2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

396588:TGR7 RS10445
gene id: 396588:TGR7_RS10445
uniprot id: B8GTS0
names: Caution
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

396588:TGR7 RS11530
gene id: 396588:TGR7_RS11530
uniprot id: B8GV36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

396588:TGR7 RS13125
gene id: 396588:TGR7_RS13125
uniprot id: B8GM99
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

396588:TGR7 RS11215
gene id: 396588:TGR7_RS11215
uniprot id: B8GUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS01745
gene id: 396588:TGR7_RS01745
uniprot id: B8GUU2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

396588:TGR7 RS09025
gene id: 396588:TGR7_RS09025
uniprot id: B8GSH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

396588:TGR7 RS00270
gene id: 396588:TGR7_RS00270
uniprot id: B8GT99
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

396588:TGR7 RS12680
gene id: 396588:TGR7_RS12680
uniprot id: B8GM15
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS07740
gene id: 396588:TGR7_RS07740
uniprot id: B8GRS3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

396588:TGR7 RS06720
gene id: 396588:TGR7_RS06720
uniprot id: B8GR06
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

396588:TGR7 RS04250
gene id: 396588:TGR7_RS04250
uniprot id: B8GN90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

396588:TGR7 RS05035
gene id: 396588:TGR7_RS05035
uniprot id: B8GP06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

396588:TGR7 RS04490
gene id: 396588:TGR7_RS04490
uniprot id: B8GND5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

396588:TGR7 RS04335
gene id: 396588:TGR7_RS04335
uniprot id: B8GNA7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

396588:TGR7 RS10070
gene id: 396588:TGR7_RS10070
uniprot id: B8GT76
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

396588:TGR7 RS06835
gene id: 396588:TGR7_RS06835
uniprot id: B8GR29
names: Similarity
messages: Belongs to the SfsA family.

396588:TGR7 RS00145
gene id: 396588:TGR7_RS00145
uniprot id: B8GSU8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

396588:TGR7 RS05020
gene id: 396588:TGR7_RS05020
uniprot id: B8GP03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

396588:TGR7 RS13705
gene id: 396588:TGR7_RS13705
uniprot id: B8GMZ0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

396588:TGR7 RS16280
gene id: 396588:TGR7_RS16280
uniprot id: B8GQT8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

396588:TGR7 RS07545
gene id: 396588:TGR7_RS07545
uniprot id: B8GRN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

396588:TGR7 RS05490
gene id: 396588:TGR7_RS05490
uniprot id: B8GPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

396588:TGR7 RS16085
gene id: 396588:TGR7_RS16085
uniprot id: B8GQQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

396588:TGR7 RS00985
gene id: 396588:TGR7_RS00985
uniprot id: B8GU15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

396588:TGR7 RS13200
gene id: 396588:TGR7_RS13200
uniprot id: B8GMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

396588:TGR7 RS16565
gene id: 396588:TGR7_RS16565
uniprot id: B8GRB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

396588:TGR7 RS13790
gene id: 396588:TGR7_RS13790
uniprot id: B8GN06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

396588:TGR7 RS03830
gene id: 396588:TGR7_RS03830
uniprot id: B8GMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

396588:TGR7 RS04185
gene id: 396588:TGR7_RS04185
uniprot id: B8GN77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

396588:TGR7 RS15030
gene id: 396588:TGR7_RS15030
uniprot id: B8GPE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

396588:TGR7 RS12225
gene id: 396588:TGR7_RS12225
uniprot id: B8GLF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

396588:TGR7 RS01610
gene id: 396588:TGR7_RS01610
uniprot id: B8GUR4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

396588:TGR7 RS02845
gene id: 396588:TGR7_RS02845
uniprot id: B8GLR7
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

396588:TGR7 RS15665
gene id: 396588:TGR7_RS15665
uniprot id: B8GQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

396588:TGR7 RS10300
gene id: 396588:TGR7_RS10300
uniprot id: B8GTP3
names: Similarity
messages: Belongs to the HesB/IscA family.

396588:TGR7 RS04030
gene id: 396588:TGR7_RS04030
uniprot id: B8GN46
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

396588:TGR7 RS01680
gene id: 396588:TGR7_RS01680
uniprot id: B8GUS8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

396588:TGR7 RS04245
gene id: 396588:TGR7_RS04245
uniprot id: B8GN89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

396588:TGR7 RS05805
gene id: 396588:TGR7_RS05805
uniprot id: B8GQ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

396588:TGR7 RS13825
gene id: 396588:TGR7_RS13825
uniprot id: B8GN13
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

396588:TGR7 RS04160
gene id: 396588:TGR7_RS04160
uniprot id: B8GN72
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS12360
gene id: 396588:TGR7_RS12360
uniprot id: B8GLI3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

396588:TGR7 RS14505
gene id: 396588:TGR7_RS14505
uniprot id: B8GP44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

396588:TGR7 RS13690
gene id: 396588:TGR7_RS13690
uniprot id: B8GMY7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

396588:TGR7 RS04225
gene id: 396588:TGR7_RS04225
uniprot id: B8GN85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

396588:TGR7 RS11380
gene id: 396588:TGR7_RS11380
uniprot id: B8GV07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

396588:TGR7 RS00030
gene id: 396588:TGR7_RS00030
uniprot id: B8GSS6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

396588:TGR7 RS16645
gene id: 396588:TGR7_RS16645
uniprot id: B8GRD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

396588:TGR7 RS07530
gene id: 396588:TGR7_RS07530
uniprot id: B8GRN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

396588:TGR7 RS14850
gene id: 396588:TGR7_RS14850
uniprot id: B8GPB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

396588:TGR7 RS12645
gene id: 396588:TGR7_RS12645
uniprot id: B8GM08
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS16120
gene id: 396588:TGR7_RS16120
uniprot id: B8GQQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

396588:TGR7 RS12170
gene id: 396588:TGR7_RS12170
uniprot id: B8GLE5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

396588:TGR7 RS08415
gene id: 396588:TGR7_RS08415
uniprot id: B8GS57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

396588:TGR7 RS03775
gene id: 396588:TGR7_RS03775
uniprot id: B8GMM3
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

396588:TGR7 RS14500
gene id: 396588:TGR7_RS14500
uniprot id: B8GP43
names: Similarity
messages: Belongs to the pyruvate kinase family.

396588:TGR7 RS06410
gene id: 396588:TGR7_RS06410
uniprot id: B8GQH2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

396588:TGR7 RS14985
gene id: 396588:TGR7_RS14985
uniprot id: B8GPD7
names: Similarity
messages: Belongs to the peptidase M16 family.

396588:TGR7 RS09595
gene id: 396588:TGR7_RS09595
uniprot id: B8GSX9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

396588:TGR7 RS08670
gene id: 396588:TGR7_RS08670
uniprot id: B8GSA9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

396588:TGR7 RS13595
gene id: 396588:TGR7_RS13595
uniprot id: B8GMW7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

396588:TGR7 RS09625
gene id: 396588:TGR7_RS09625
uniprot id: B8GSY5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS03790
gene id: 396588:TGR7_RS03790
uniprot id: B8GMM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

396588:TGR7 RS14185
gene id: 396588:TGR7_RS14185
uniprot id: B8GNK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS16625
gene id: 396588:TGR7_RS16625
uniprot id: B8GRC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

396588:TGR7 RS02825
gene id: 396588:TGR7_RS02825
uniprot id: B8GLR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

396588:TGR7 RS03395
gene id: 396588:TGR7_RS03395
uniprot id: B8GME7
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

396588:TGR7 RS10240
gene id: 396588:TGR7_RS10240
uniprot id: B8GTN1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

396588:TGR7 RS04560
gene id: 396588:TGR7_RS04560
uniprot id: B8GNR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS06235
gene id: 396588:TGR7_RS06235
uniprot id: B8GQD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

396588:TGR7 RS02195
gene id: 396588:TGR7_RS02195
uniprot id: B8GL24
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

396588:TGR7 RS00910
gene id: 396588:TGR7_RS00910
uniprot id: B8GU00
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

396588:TGR7 RS06140
gene id: 396588:TGR7_RS06140
uniprot id: B8GQB8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

396588:TGR7 RS15920
gene id: 396588:TGR7_RS15920
uniprot id: B8GQL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

396588:TGR7 RS01380
gene id: 396588:TGR7_RS01380
uniprot id: B8GU95
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS03765
gene id: 396588:TGR7_RS03765
uniprot id: B8GMM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

396588:TGR7 RS07975
gene id: 396588:TGR7_RS07975
uniprot id: B8GRW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

396588:TGR7 RS06840
gene id: 396588:TGR7_RS06840
uniprot id: B8GR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

396588:TGR7 RS00315
gene id: 396588:TGR7_RS00315
uniprot id: B8GTA8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

396588:TGR7 RS12675
gene id: 396588:TGR7_RS12675
uniprot id: B8GM14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

396588:TGR7 RS00720
gene id: 396588:TGR7_RS00720
uniprot id: B8GTI6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

396588:TGR7 RS12685
gene id: 396588:TGR7_RS12685
uniprot id: B8GM16
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS06855
gene id: 396588:TGR7_RS06855
uniprot id: B8GR33
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS08085
gene id: 396588:TGR7_RS08085
uniprot id: B8GRZ1
names: Subcellular Location Annotation
messages: Membrane

396588:TGR7 RS07810
gene id: 396588:TGR7_RS07810
uniprot id: B8GRT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS15675
gene id: 396588:TGR7_RS15675
uniprot id: B8GQ46
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

396588:TGR7 RS14555
gene id: 396588:TGR7_RS14555
uniprot id: B8GP54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

396588:TGR7 RS10145
gene id: 396588:TGR7_RS10145
uniprot id: B8GTL2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.