388459:MI149 RS00745
gene id: 388459:MI149_RS00745
uniprot id: A0A9Q8PSJ8
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

388459:MI149 RS06800
gene id: 388459:MI149_RS06800
uniprot id: A0A9Q8PV27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

388459:MI149 RS11270
gene id: 388459:MI149_RS11270
uniprot id: A0A9Q8PX23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

388459:MI149 RS20300
gene id: 388459:MI149_RS20300
uniprot id: A0A9Q8UXU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

388459:MI149 RS14805
gene id: 388459:MI149_RS14805
uniprot id: A0A9Q8PN55
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

388459:MI149 RS22160
gene id: 388459:MI149_RS22160
uniprot id: A0A9Q8PQM2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

388459:MI149 RS13965
gene id: 388459:MI149_RS13965
uniprot id: A0A9Q8PY22
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

388459:MI149 RS11335
gene id: 388459:MI149_RS11335
uniprot id: A0A9Q8PZ03
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

388459:MI149 RS09300
gene id: 388459:MI149_RS09300
uniprot id: A0A9Q8V0X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388459:MI149 RS23420
gene id: 388459:MI149_RS23420
uniprot id: A0A9Q8UY95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

388459:MI149 RS00590
gene id: 388459:MI149_RS00590
uniprot id: A0A9Q8PT69
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

388459:MI149 RS26235
gene id: 388459:MI149_RS26235
uniprot id: A0A9Q8PRG3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

388459:MI149 RS16990
gene id: 388459:MI149_RS16990
uniprot id: A0A9Q8PP46
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

388459:MI149 RS24030
gene id: 388459:MI149_RS24030
uniprot id: A0A9Q8UYC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

388459:MI149 RS28565
gene id: 388459:MI149_RS28565
uniprot id: A0A9Q8PSG7
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

388459:MI149 RS10815
gene id: 388459:MI149_RS10815
uniprot id: A0A9Q8V216
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

388459:MI149 RS14235
gene id: 388459:MI149_RS14235
uniprot id: A0A9Q8PYL8
names: Similarity
messages: Belongs to the peptidase C40 family.

388459:MI149 RS20255
gene id: 388459:MI149_RS20255
uniprot id: A0A9Q8PPS9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

388459:MI149 RS27255
gene id: 388459:MI149_RS27255
uniprot id: A0A9Q8UYY2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

388459:MI149 RS22305
gene id: 388459:MI149_RS22305
uniprot id: A0A9Q8UY52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

388459:MI149 RS23140
gene id: 388459:MI149_RS23140
uniprot id: A0A9Q8UY99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

388459:MI149 RS17450
gene id: 388459:MI149_RS17450
uniprot id: A0A9Q8UXR5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388459:MI149 RS27375
gene id: 388459:MI149_RS27375
uniprot id: A0A9Q8PYA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

388459:MI149 RS26335
gene id: 388459:MI149_RS26335
uniprot id: A0A9Q8PS11
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388459:MI149 RS22985
gene id: 388459:MI149_RS22985
uniprot id: A0A9Q8UY70
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388459:MI149 RS09420
gene id: 388459:MI149_RS09420
uniprot id: A0A9Q8PWJ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388459:MI149 RS23425
gene id: 388459:MI149_RS23425
uniprot id: A0A9Q8UYS1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

388459:MI149 RS00570
gene id: 388459:MI149_RS00570
uniprot id: A0A9Q8PSY4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

388459:MI149 RS13205
gene id: 388459:MI149_RS13205
uniprot id: A0A9Q8V1N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

388459:MI149 RS10230
gene id: 388459:MI149_RS10230
uniprot id: A0A9Q8V0S6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

388459:MI149 RS07495
gene id: 388459:MI149_RS07495
uniprot id: A0A9Q8PVS8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388459:MI149 RS06590
gene id: 388459:MI149_RS06590
uniprot id: A0A9Q8PVH2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

388459:MI149 RS24650
gene id: 388459:MI149_RS24650
uniprot id: A0A9Q8PRB6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

388459:MI149 RS09475
gene id: 388459:MI149_RS09475
uniprot id: A0A9Q8PYZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

388459:MI149 RS29225
gene id: 388459:MI149_RS29225
uniprot id: A0A9Q8PSP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

388459:MI149 RS17215
gene id: 388459:MI149_RS17215
uniprot id: A0A9Q8PYB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

388459:MI149 RS11405
gene id: 388459:MI149_RS11405
uniprot id: A0A9Q8PWX7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

388459:MI149 RS14830
gene id: 388459:MI149_RS14830
uniprot id: A0A9Q8PNB4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

388459:MI149 RS03615
gene id: 388459:MI149_RS03615
uniprot id: A0A9Q8PU59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

388459:MI149 RS04315
gene id: 388459:MI149_RS04315
uniprot id: A0A9Q8UZV7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

388459:MI149 RS20855
gene id: 388459:MI149_RS20855
uniprot id: A0A9Q8PXE8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

388459:MI149 RS28995
gene id: 388459:MI149_RS28995
uniprot id: A0A9Q8PT35
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

388459:MI149 RS12250
gene id: 388459:MI149_RS12250
uniprot id: A0A9Q8V203
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

388459:MI149 RS11020
gene id: 388459:MI149_RS11020
uniprot id: A0A9Q8V1S2
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

388459:MI149 RS26565
gene id: 388459:MI149_RS26565
uniprot id: A0A9Q8UYS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388459:MI149 RS25435
gene id: 388459:MI149_RS25435
uniprot id: A0A9Q8PXK7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

388459:MI149 RS09760
gene id: 388459:MI149_RS09760
uniprot id: A0A9Q8PWI6
names: Similarity
messages: Belongs to the cytochrome P450 family.

388459:MI149 RS11980
gene id: 388459:MI149_RS11980
uniprot id: A0A9Q8V1F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

388459:MI149 RS00815
gene id: 388459:MI149_RS00815
uniprot id: A0A9Q8UZE0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

388459:MI149 RS17210
gene id: 388459:MI149_RS17210
uniprot id: A0A9Q8PNQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

388459:MI149 RS09250
gene id: 388459:MI149_RS09250
uniprot id: A0A9Q8V0Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388459:MI149 RS10630
gene id: 388459:MI149_RS10630
uniprot id: A0A9Q8V0M2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

388459:MI149 RS20660
gene id: 388459:MI149_RS20660
uniprot id: A0A9Q8PPR0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

388459:MI149 RS26890
gene id: 388459:MI149_RS26890
uniprot id: A0A9Q8PRZ7
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS13940
gene id: 388459:MI149_RS13940
uniprot id: A0A9Q8V1T0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

388459:MI149 RS07485
gene id: 388459:MI149_RS07485
uniprot id: A0A9Q8PVK6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

388459:MI149 RS29925
gene id: 388459:MI149_RS29925
uniprot id: A0A9Q8PZ35
names: Similarity
messages: Belongs to the peptidase C40 family.

388459:MI149 RS26330
gene id: 388459:MI149_RS26330
uniprot id: A0A9Q8PRV3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388459:MI149 RS23620
gene id: 388459:MI149_RS23620
uniprot id: A0A9Q8PQX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

388459:MI149 RS25415
gene id: 388459:MI149_RS25415
uniprot id: A0A9Q8PRJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

388459:MI149 RS13800
gene id: 388459:MI149_RS13800
uniprot id: A0A9Q8V2A0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

388459:MI149 RS30035
gene id: 388459:MI149_RS30035
uniprot id: A0A9Q8PXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

388459:MI149 RS11295
gene id: 388459:MI149_RS11295
uniprot id: A0A9Q8PWX5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

388459:MI149 RS03075
gene id: 388459:MI149_RS03075
uniprot id: A0A9Q8PUK6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

388459:MI149 RS24555
gene id: 388459:MI149_RS24555
uniprot id: A0A9Q8PR88
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

388459:MI149 RS05745
gene id: 388459:MI149_RS05745
uniprot id: A0A9Q8PV61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

388459:MI149 RS21790
gene id: 388459:MI149_RS21790
uniprot id: A0A9Q8UYH9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388459:MI149 RS24460
gene id: 388459:MI149_RS24460
uniprot id: A0A9Q8V1S5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

388459:MI149 RS17125
gene id: 388459:MI149_RS17125
uniprot id: A0A9Q8PNP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

388459:MI149 RS18785
gene id: 388459:MI149_RS18785
uniprot id: A0A9Q8PPC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

388459:MI149 RS18985
gene id: 388459:MI149_RS18985
uniprot id: A0A9Q8PPJ4
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

388459:MI149 RS06145
gene id: 388459:MI149_RS06145
uniprot id: A0A9Q8PV49
names: Subcellular Location Annotation
messages: Cytoplasm

388459:MI149 RS05190
gene id: 388459:MI149_RS05190
uniprot id: A0A9Q8PUU7
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS14785
gene id: 388459:MI149_RS14785
uniprot id: A0A9Q8PN52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

388459:MI149 RS05945
gene id: 388459:MI149_RS05945
uniprot id: A0A9Q8PV86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

388459:MI149 RS00210
gene id: 388459:MI149_RS00210
uniprot id: A0A9Q8PSE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

388459:MI149 RS23555
gene id: 388459:MI149_RS23555
uniprot id: A0A9Q8PQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

388459:MI149 RS10130
gene id: 388459:MI149_RS10130
uniprot id: A0A9Q8V113
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388459:MI149 RS15115
gene id: 388459:MI149_RS15115
uniprot id: A0A9Q8PN26
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS00515
gene id: 388459:MI149_RS00515
uniprot id: A0A9Q8PTC7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388459:MI149 RS29120
gene id: 388459:MI149_RS29120
uniprot id: A0A9Q8PSA3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

388459:MI149 RS23415
gene id: 388459:MI149_RS23415
uniprot id: A0A9Q8UYB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

388459:MI149 RS19950
gene id: 388459:MI149_RS19950
uniprot id: A0A9Q8UXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

388459:MI149 RS13770
gene id: 388459:MI149_RS13770
uniprot id: A0A9Q8PXA3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

388459:MI149 RS10470
gene id: 388459:MI149_RS10470
uniprot id: A0A9Q8V1H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

388459:MI149 RS16790
gene id: 388459:MI149_RS16790
uniprot id: A0A9Q8UX55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

388459:MI149 RS11635
gene id: 388459:MI149_RS11635
uniprot id: A0A9Q8PXM6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388459:MI149 RS07100
gene id: 388459:MI149_RS07100
uniprot id: A0A9Q8V0J5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

388459:MI149 RS09480
gene id: 388459:MI149_RS09480
uniprot id: A0A9Q8V167
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

388459:MI149 RS23180
gene id: 388459:MI149_RS23180
uniprot id: A0A9Q8PQS4
names: Similarity
messages: Belongs to the LOG family.

388459:MI149 RS06005
gene id: 388459:MI149_RS06005
uniprot id: A0A9Q8PVA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

388459:MI149 RS14660
gene id: 388459:MI149_RS14660
uniprot id: A0A9Q8PMY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

388459:MI149 RS09855
gene id: 388459:MI149_RS09855
uniprot id: A0A9Q8PWI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

388459:MI149 RS02245
gene id: 388459:MI149_RS02245
uniprot id: A0A9Q8PTR1
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

388459:MI149 RS23195
gene id: 388459:MI149_RS23195
uniprot id: A0A9Q8PQT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

388459:MI149 RS26810
gene id: 388459:MI149_RS26810
uniprot id: A0A9Q8UYW0
names: Subcellular Location Annotation
messages: Cytoplasm

388459:MI149 RS07005
gene id: 388459:MI149_RS07005
uniprot id: A0A9Q8V0L2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

388459:MI149 RS12355
gene id: 388459:MI149_RS12355
uniprot id: A0A9Q8PW92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

388459:MI149 RS21775
gene id: 388459:MI149_RS21775
uniprot id: A0A9Q8UXZ4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

388459:MI149 RS20050
gene id: 388459:MI149_RS20050
uniprot id: A0A9Q8UXR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

388459:MI149 RS13995
gene id: 388459:MI149_RS13995
uniprot id: A0A9Q8PYI3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

388459:MI149 RS10120
gene id: 388459:MI149_RS10120
uniprot id: A0A9Q8V1J8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

388459:MI149 RS29910
gene id: 388459:MI149_RS29910
uniprot id: A0A9Q8PYQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

388459:MI149 RS20825
gene id: 388459:MI149_RS20825
uniprot id: A0A9Q8UYC2
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

388459:MI149 RS01505
gene id: 388459:MI149_RS01505
uniprot id: A0A9Q8PU21
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388459:MI149 RS10540
gene id: 388459:MI149_RS10540
uniprot id: A0A9Q8PWF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388459:MI149 RS11060
gene id: 388459:MI149_RS11060
uniprot id: A0A9Q8PXF0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

388459:MI149 RS10530
gene id: 388459:MI149_RS10530
uniprot id: A0A9Q8PVA0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

388459:MI149 RS15695
gene id: 388459:MI149_RS15695
uniprot id: A0A9Q8PN75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

388459:MI149 RS20045
gene id: 388459:MI149_RS20045
uniprot id: A0A9Q8UXT2
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS18360
gene id: 388459:MI149_RS18360
uniprot id: A0A9Q8PP37
names: Similarity
messages: Belongs to the leucine-binding protein family.

388459:MI149 RS22180
gene id: 388459:MI149_RS22180
uniprot id: A0A9Q8PQL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

388459:MI149 RS04310
gene id: 388459:MI149_RS04310
uniprot id: A0A9Q8V013
names: Similarity
messages: Belongs to the UPF0336 family.

388459:MI149 RS24395
gene id: 388459:MI149_RS24395
uniprot id: A0A9Q8PRS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor.
messages: Belongs to the anti-sigma-K factor family.
messages: Cell membrane
messages: The cytosolic domain interacts with sigma factor SigK.

388459:MI149 RS06430
gene id: 388459:MI149_RS06430
uniprot id: A0A9Q8PVF1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

388459:MI149 RS29885
gene id: 388459:MI149_RS29885
uniprot id: A0A9Q8V227
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

388459:MI149 RS29000
gene id: 388459:MI149_RS29000
uniprot id: A0A9Q8UZB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

388459:MI149 RS26065
gene id: 388459:MI149_RS26065
uniprot id: A0A9Q8PRS3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

388459:MI149 RS22330
gene id: 388459:MI149_RS22330
uniprot id: A0A9Q8PQ89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

388459:MI149 RS23705
gene id: 388459:MI149_RS23705
uniprot id: A0A9Q8PQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

388459:MI149 RS21350
gene id: 388459:MI149_RS21350
uniprot id: A0A9Q8UXW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

388459:MI149 RS10805
gene id: 388459:MI149_RS10805
uniprot id: A0A9Q8PWQ5
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

388459:MI149 RS23600
gene id: 388459:MI149_RS23600
uniprot id: A0A9Q8UYT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

388459:MI149 RS03785
gene id: 388459:MI149_RS03785
uniprot id: A0A9Q8PUA4
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS23410
gene id: 388459:MI149_RS23410
uniprot id: A0A9Q8UY96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

388459:MI149 RS06010
gene id: 388459:MI149_RS06010
uniprot id: A0A9Q8V0F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

388459:MI149 RS23430
gene id: 388459:MI149_RS23430
uniprot id: A0A9Q8PR33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

388459:MI149 RS18845
gene id: 388459:MI149_RS18845
uniprot id: A0A9Q8UY06
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

388459:MI149 RS01705
gene id: 388459:MI149_RS01705
uniprot id: A0A9Q8UZH5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

388459:MI149 RS12400
gene id: 388459:MI149_RS12400
uniprot id: A0A9Q8V176
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

388459:MI149 RS10360
gene id: 388459:MI149_RS10360
uniprot id: A0A9Q8PVB8
names: Similarity
messages: Belongs to the YciI family.

388459:MI149 RS05920
gene id: 388459:MI149_RS05920
uniprot id: A0A9Q8V0E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

388459:MI149 RS17950
gene id: 388459:MI149_RS17950
uniprot id: A0A9Q8PNZ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388459:MI149 RS18130
gene id: 388459:MI149_RS18130
uniprot id: A0A9Q8PXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

388459:MI149 RS26455
gene id: 388459:MI149_RS26455
uniprot id: A0A9Q8PRT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388459:MI149 RS12365
gene id: 388459:MI149_RS12365
uniprot id: A0A9Q8PXB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

388459:MI149 RS18400
gene id: 388459:MI149_RS18400
uniprot id: A0A9Q8PPC8
names: Similarity
messages: Belongs to the Dps family.

388459:MI149 RS29005
gene id: 388459:MI149_RS29005
uniprot id: A0A9Q8UZ70
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388459:MI149 RS25495
gene id: 388459:MI149_RS25495
uniprot id: A0A9Q8PRK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

388459:MI149 RS27370
gene id: 388459:MI149_RS27370
uniprot id: A0A9Q8PS72
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

388459:MI149 RS23545
gene id: 388459:MI149_RS23545
uniprot id: A0A9Q8PRH5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

388459:MI149 RS10725
gene id: 388459:MI149_RS10725
uniprot id: A0A9Q8PXA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388459:MI149 RS29830
gene id: 388459:MI149_RS29830
uniprot id: A0A9Q8PYR8
names: Similarity
messages: Belongs to the peptidase S8 family.

388459:MI149 RS05925
gene id: 388459:MI149_RS05925
uniprot id: A0A9Q8V067
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

388459:MI149 RS09425
gene id: 388459:MI149_RS09425
uniprot id: A0A9Q8PWN5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388459:MI149 RS27095
gene id: 388459:MI149_RS27095
uniprot id: A0A9Q8PSE3
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS05955
gene id: 388459:MI149_RS05955
uniprot id: A0A9Q8PU96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

388459:MI149 RS26540
gene id: 388459:MI149_RS26540
uniprot id: A0A9Q8PRU7
names: Similarity
messages: Belongs to the UPF0145 family.

388459:MI149 RS26370
gene id: 388459:MI149_RS26370
uniprot id: A0A9Q8UYV7
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

388459:MI149 RS26670
gene id: 388459:MI149_RS26670
uniprot id: A0A9Q8PS62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

388459:MI149 RS28250
gene id: 388459:MI149_RS28250
uniprot id: A0A9Q8PSG2
names: Similarity
messages: Belongs to the MmpS family.

388459:MI149 RS29955
gene id: 388459:MI149_RS29955
uniprot id: A0A9Q8PZH1
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS11135
gene id: 388459:MI149_RS11135
uniprot id: A0A9Q8PWR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

388459:MI149 RS13855
gene id: 388459:MI149_RS13855
uniprot id: A0A9Q8V1S4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388459:MI149 RS05420
gene id: 388459:MI149_RS05420
uniprot id: A0A9Q8V0S9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

388459:MI149 RS12345
gene id: 388459:MI149_RS12345
uniprot id: A0A9Q8PXG0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388459:MI149 RS17140
gene id: 388459:MI149_RS17140
uniprot id: A0A9Q8PNX3
names: Similarity
messages: Belongs to the UPF0749 family.

388459:MI149 RS18595
gene id: 388459:MI149_RS18595
uniprot id: A0A9Q8UXZ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388459:MI149 RS12570
gene id: 388459:MI149_RS12570
uniprot id: A0A9Q8PWV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

388459:MI149 RS26250
gene id: 388459:MI149_RS26250
uniprot id: A0A9Q8V280
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

388459:MI149 RS27505
gene id: 388459:MI149_RS27505
uniprot id: A0A9Q8UZ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

388459:MI149 RS06020
gene id: 388459:MI149_RS06020
uniprot id: A0A9Q8V0D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

388459:MI149 RS19450
gene id: 388459:MI149_RS19450
uniprot id: A0A9Q8UXM7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

388459:MI149 RS10535
gene id: 388459:MI149_RS10535
uniprot id: A0A9Q8PV99
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

388459:MI149 RS27395
gene id: 388459:MI149_RS27395
uniprot id: A0A9Q8PSY2
names: Similarity
messages: Belongs to the CFA/CMAS family.

388459:MI149 RS11465
gene id: 388459:MI149_RS11465
uniprot id: A0A9Q8PWZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

388459:MI149 RS07290
gene id: 388459:MI149_RS07290
uniprot id: A0A9Q8PY68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

388459:MI149 RS06690
gene id: 388459:MI149_RS06690
uniprot id: A0A9Q8V086
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

388459:MI149 RS12280
gene id: 388459:MI149_RS12280
uniprot id: A0A9Q8PXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

388459:MI149 RS06085
gene id: 388459:MI149_RS06085
uniprot id: A0A9Q8V0F8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

388459:MI149 RS14450
gene id: 388459:MI149_RS14450
uniprot id: A0A9Q8V2F0
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS07895
gene id: 388459:MI149_RS07895
uniprot id: A0A9Q8PUU5
names: Similarity
messages: Belongs to the cytochrome b560 family.

388459:MI149 RS06650
gene id: 388459:MI149_RS06650
uniprot id: A0A9Q8PV87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

388459:MI149 RS05930
gene id: 388459:MI149_RS05930
uniprot id: A0A9Q8V0C0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

388459:MI149 RS21890
gene id: 388459:MI149_RS21890
uniprot id: A0A9Q8PYR3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388459:MI149 RS23405
gene id: 388459:MI149_RS23405
uniprot id: A0A9Q8UYC3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

388459:MI149 RS08605
gene id: 388459:MI149_RS08605
uniprot id: A0A9Q8V0H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

388459:MI149 RS00730
gene id: 388459:MI149_RS00730
uniprot id: A0A9Q8UZA1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

388459:MI149 RS10335
gene id: 388459:MI149_RS10335
uniprot id: A0A9Q8PWB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

388459:MI149 RS23835
gene id: 388459:MI149_RS23835
uniprot id: A0A9Q8PY90
names: Similarity
names: Subunit
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
messages: Homodimer.

388459:MI149 RS07155
gene id: 388459:MI149_RS07155
uniprot id: A0A9Q8PVG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

388459:MI149 RS11605
gene id: 388459:MI149_RS11605
uniprot id: A0A9Q8PX65
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

388459:MI149 RS08870
gene id: 388459:MI149_RS08870
uniprot id: A0A9Q8PVQ4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

388459:MI149 RS19010
gene id: 388459:MI149_RS19010
uniprot id: A0A9Q8UXN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

388459:MI149 RS15110
gene id: 388459:MI149_RS15110
uniprot id: A0A9Q8PXA0
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS10600
gene id: 388459:MI149_RS10600
uniprot id: A0A9Q8PW93
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

388459:MI149 RS29235
gene id: 388459:MI149_RS29235
uniprot id: A0A9Q8UZD2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

388459:MI149 RS13990
gene id: 388459:MI149_RS13990
uniprot id: A0A9Q8PXR3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

388459:MI149 RS17055
gene id: 388459:MI149_RS17055
uniprot id: A0A9Q8PNS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

388459:MI149 RS05235
gene id: 388459:MI149_RS05235
uniprot id: A0A9Q8V030
names: Subcellular Location Annotation
messages: Cytoplasm

388459:MI149 RS20025
gene id: 388459:MI149_RS20025
uniprot id: A0A9Q8PQ38
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

388459:MI149 RS05940
gene id: 388459:MI149_RS05940
uniprot id: A0A9Q8V0W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

388459:MI149 RS26175
gene id: 388459:MI149_RS26175
uniprot id: A0A9Q8PSG4
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

388459:MI149 RS18550
gene id: 388459:MI149_RS18550
uniprot id: A0A9Q8PPR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

388459:MI149 RS26600
gene id: 388459:MI149_RS26600
uniprot id: A0A9Q8PS04
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

388459:MI149 RS23265
gene id: 388459:MI149_RS23265
uniprot id: A0A9Q8PQI9
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

388459:MI149 RS19955
gene id: 388459:MI149_RS19955
uniprot id: A0A9Q8UXS8
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS11645
gene id: 388459:MI149_RS11645
uniprot id: A0A9Q8PX13
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS26650
gene id: 388459:MI149_RS26650
uniprot id: A0A9Q8PS89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

388459:MI149 RS00675
gene id: 388459:MI149_RS00675
uniprot id: A0A9Q8PYE2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

388459:MI149 RS05950
gene id: 388459:MI149_RS05950
uniprot id: A0A9Q8PU98
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

388459:MI149 RS15200
gene id: 388459:MI149_RS15200
uniprot id: A0A9Q8PN68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

388459:MI149 RS05995
gene id: 388459:MI149_RS05995
uniprot id: A0A9Q8PV25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

388459:MI149 RS19365
gene id: 388459:MI149_RS19365
uniprot id: A0A9Q8PPR2
names: Similarity
messages: Belongs to the cytochrome P450 family.

388459:MI149 RS21995
gene id: 388459:MI149_RS21995
uniprot id: A0A9Q8PQJ5
names: Function
names: Subunit
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

388459:MI149 RS19190
gene id: 388459:MI149_RS19190
uniprot id: A0A9Q8UXI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

388459:MI149 RS07275
gene id: 388459:MI149_RS07275
uniprot id: A0A9Q8V0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

388459:MI149 RS05385
gene id: 388459:MI149_RS05385
uniprot id: A0A9Q8PUH1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

388459:MI149 RS22235
gene id: 388459:MI149_RS22235
uniprot id: A0A9Q8PQ78
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

388459:MI149 RS06000
gene id: 388459:MI149_RS06000
uniprot id: A0A9Q8PUQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

388459:MI149 RS26300
gene id: 388459:MI149_RS26300
uniprot id: A0A9Q8UZB2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

388459:MI149 RS13765
gene id: 388459:MI149_RS13765
uniprot id: A0A9Q8PXU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

388459:MI149 RS07730
gene id: 388459:MI149_RS07730
uniprot id: A0A9Q8PVD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

388459:MI149 RS06035
gene id: 388459:MI149_RS06035
uniprot id: A0A9Q8PV95
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

388459:MI149 RS29010
gene id: 388459:MI149_RS29010
uniprot id: A0A9Q8UZ77
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

388459:MI149 RS27495
gene id: 388459:MI149_RS27495
uniprot id: A0A9Q8PS58
names: Similarity
messages: Belongs to the CsoR family.

388459:MI149 RS10135
gene id: 388459:MI149_RS10135
uniprot id: A0A9Q8V0T1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388459:MI149 RS11215
gene id: 388459:MI149_RS11215
uniprot id: A0A9Q8PWS9
names: Similarity
messages: Belongs to the P(II) protein family.

388459:MI149 RS00585
gene id: 388459:MI149_RS00585
uniprot id: A0A9Q8PTR5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

388459:MI149 RS25325
gene id: 388459:MI149_RS25325
uniprot id: A0A9Q8PR60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

388459:MI149 RS10745
gene id: 388459:MI149_RS10745
uniprot id: A0A9Q8V183
names: Similarity
messages: Belongs to the phosphoribulokinase family.

388459:MI149 RS17135
gene id: 388459:MI149_RS17135
uniprot id: A0A9Q8PNT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

388459:MI149 RS15035
gene id: 388459:MI149_RS15035
uniprot id: A0A9Q8PN18
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388459:MI149 RS03835
gene id: 388459:MI149_RS03835
uniprot id: A0A9Q8PTJ9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

388459:MI149 RS16960
gene id: 388459:MI149_RS16960
uniprot id: A0A9Q8PNW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

388459:MI149 RS09485
gene id: 388459:MI149_RS09485
uniprot id: A0A9Q8PWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

388459:MI149 RS08465
gene id: 388459:MI149_RS08465
uniprot id: A0A9Q8V0S8
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS06985
gene id: 388459:MI149_RS06985
uniprot id: A0A9Q8PVE9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388459:MI149 RS06040
gene id: 388459:MI149_RS06040
uniprot id: A0A9Q8PUA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

388459:MI149 RS03925
gene id: 388459:MI149_RS03925
uniprot id: A0A9Q8PUD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

388459:MI149 RS06015
gene id: 388459:MI149_RS06015
uniprot id: A0A9Q8V076
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

388459:MI149 RS17955
gene id: 388459:MI149_RS17955
uniprot id: A0A9Q8PPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

388459:MI149 RS24720
gene id: 388459:MI149_RS24720
uniprot id: A0A9Q8PQZ8
names: Similarity
messages: Belongs to the citrate synthase family.

388459:MI149 RS14055
gene id: 388459:MI149_RS14055
uniprot id: A0A9Q8PWT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

388459:MI149 RS29900
gene id: 388459:MI149_RS29900
uniprot id: A0A9Q8V2I7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

388459:MI149 RS10545
gene id: 388459:MI149_RS10545
uniprot id: A0A9Q8V1H2
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

388459:MI149 RS07645
gene id: 388459:MI149_RS07645
uniprot id: A0A9Q8V1M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388459:MI149 RS02310
gene id: 388459:MI149_RS02310
uniprot id: A0A9Q8PTT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

388459:MI149 RS05645
gene id: 388459:MI149_RS05645
uniprot id: A0A9Q8PUX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

388459:MI149 RS18125
gene id: 388459:MI149_RS18125
uniprot id: A0A9Q8PP28
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

388459:MI149 RS18355
gene id: 388459:MI149_RS18355
uniprot id: A0A9Q8PPD8
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS05650
gene id: 388459:MI149_RS05650
uniprot id: A0A9Q8PUK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

388459:MI149 RS10920
gene id: 388459:MI149_RS10920
uniprot id: A0A9Q8V1R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

388459:MI149 RS24695
gene id: 388459:MI149_RS24695
uniprot id: A0A9Q8UYG6
names: Similarity
messages: Belongs to the citrate synthase family.

388459:MI149 RS05905
gene id: 388459:MI149_RS05905
uniprot id: A0A9Q8PV04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

388459:MI149 RS28580
gene id: 388459:MI149_RS28580
uniprot id: A0A9Q8UZ95
names: Similarity
messages: Belongs to the Nudix hydrolase family.

388459:MI149 RS10595
gene id: 388459:MI149_RS10595
uniprot id: A0A9Q8PW59
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

388459:MI149 RS18600
gene id: 388459:MI149_RS18600
uniprot id: A0A9Q8PPG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

388459:MI149 RS13310
gene id: 388459:MI149_RS13310
uniprot id: A0A9Q8PXT0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

388459:MI149 RS24330
gene id: 388459:MI149_RS24330
uniprot id: A0A9Q8PRI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

388459:MI149 RS09725
gene id: 388459:MI149_RS09725
uniprot id: A0A9Q8V137
names: Similarity
messages: Belongs to the Nudix hydrolase family.

388459:MI149 RS08700
gene id: 388459:MI149_RS08700
uniprot id: A0A9Q8PV21
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

388459:MI149 RS17785
gene id: 388459:MI149_RS17785
uniprot id: A0A9Q8UXG0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

388459:MI149 RS09675
gene id: 388459:MI149_RS09675
uniprot id: A0A9Q8PX54
names: Subcellular Location Annotation
messages: Membrane

388459:MI149 RS27870
gene id: 388459:MI149_RS27870
uniprot id: A0A9Q8UYY9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

388459:MI149 RS26220
gene id: 388459:MI149_RS26220
uniprot id: A0A9Q8PS28
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388459:MI149 RS06090
gene id: 388459:MI149_RS06090
uniprot id: A0A9Q8V082
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

388459:MI149 RS18505
gene id: 388459:MI149_RS18505
uniprot id: A0A9Q8UXK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

388459:MI149 RS06095
gene id: 388459:MI149_RS06095
uniprot id: A0A9Q8V0D8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388459:MI149 RS10825
gene id: 388459:MI149_RS10825
uniprot id: A0A9Q8V188
names: Similarity
messages: Belongs to the HupF/HypC family.

388459:MI149 RS09785
gene id: 388459:MI149_RS09785
uniprot id: A0A9Q8PW60
names: Similarity
messages: Belongs to the thioesterase PaaI family.

388459:MI149 RS22150
gene id: 388459:MI149_RS22150
uniprot id: A0A9Q8PQ67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

388459:MI149 RS18815
gene id: 388459:MI149_RS18815
uniprot id: A0A9Q8PP92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

388459:MI149 RS10770
gene id: 388459:MI149_RS10770
uniprot id: A0A9Q8PWW3
names: Similarity
messages: Belongs to the HupF/HypC family.

388459:MI149 RS21510
gene id: 388459:MI149_RS21510
uniprot id: A0A9Q8UY11
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

388459:MI149 RS05670
gene id: 388459:MI149_RS05670
uniprot id: A0A9Q8V0A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

388459:MI149 RS13845
gene id: 388459:MI149_RS13845
uniprot id: A0A9Q8PXB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

388459:MI149 RS03595
gene id: 388459:MI149_RS03595
uniprot id: A0A9Q8PTH2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

388459:MI149 RS25150
gene id: 388459:MI149_RS25150
uniprot id: A0A9Q8PRM1
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

388459:MI149 RS06080
gene id: 388459:MI149_RS06080
uniprot id: A0A9Q8PVB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

388459:MI149 RS02255
gene id: 388459:MI149_RS02255
uniprot id: A0A9Q8PTX4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

388459:MI149 RS06025
gene id: 388459:MI149_RS06025
uniprot id: A0A9Q8V055
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

388459:MI149 RS18120
gene id: 388459:MI149_RS18120
uniprot id: A0A9Q8PP95
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.